|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08295 |
PRK08295 |
RNA polymerase sporulation sigma factor SigH; |
8-215 |
9.39e-133 |
|
RNA polymerase sporulation sigma factor SigH;
Pssm-ID: 181361 [Multi-domain] Cd Length: 208 Bit Score: 371.16 E-value: 9.39e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 8 KLHAHFEQQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAF 87
Cdd:PRK08295 1 LRMKDYDELEDEELVELARSGDKEALEYLIEKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDYDKDKLSSFKSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 88 AELCITRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLMDVISGTKVANPEELLINREKFDDIELKMAELLSDLE 167
Cdd:PRK08295 81 AELCITRQIITAIKTANRQKHIPLNSYVSLDKPIYDEESDRTLLDVISEAKVTDPEELIISKEELEDIEEKIEELLSELE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 502819934 168 RKVLVLYLDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLEIREIT 215
Cdd:PRK08295 161 KEVLELYLDGKSYQEIAEELNRHVKSIDNALQRVKRKLEKYLENREIT 208
|
|
| spore_sigH |
TIGR02859 |
RNA polymerase sigma-H factor; Members of this protein family are RNA polymerase sigma-H ... |
13-210 |
7.16e-123 |
|
RNA polymerase sigma-H factor; Members of this protein family are RNA polymerase sigma-H factor for sporulation in endospore-forming bacteria. This protein is also called Sigma-30 and SigH. Although rather close homologs in Listeria score well against this model, Listeria does not form spores and the role of the related sigma factor in that genus is in doubt. [Transcription, Transcription factors, Cellular processes, Sporulation and germination]
Pssm-ID: 131906 [Multi-domain] Cd Length: 198 Bit Score: 346.02 E-value: 7.16e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 13 FEQQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCI 92
Cdd:TIGR02859 1 FKQLEDEEIVELARQGNTHALEYLINKYKNFVRAKARSYFLIGADKEDIIQEGMIGLYKAIRDFRPDKLSSFKAFAELCV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 93 TRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLMDVISGTKVANPEELLINREKFDDIELKMAELLSDLERKVLV 172
Cdd:TIGR02859 81 TRQIITAIKTATRQKHIPLNSYVSLNKPIYDEESDRTLLDVISGAKVTDPEELIISQEEYGDIESKMNELLSDLEWKVLQ 160
|
170 180 190
....*....|....*....|....*....|....*...
gi 502819934 173 LYLDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLE 210
Cdd:TIGR02859 161 SYLDGKSYQEIACDLNRHVKSIDNALQRVKRKLEKYLE 198
|
|
| RpoE |
COG1595 |
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ... |
16-215 |
3.97e-24 |
|
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase
Pssm-ID: 441203 [Multi-domain] Cd Length: 181 Bit Score: 94.29 E-value: 3.97e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 16 QEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDklTSFKAFAELCITRQ 95
Cdd:COG1595 2 SSDEELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGR--GSFRAWLYRIARNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 96 IITAIKTATRQKHIplnsyvsLDKPIYDEESDrtlmdvisgtkVANPEELLINREKFDDIELKMAElLSDLERKVLVL-Y 174
Cdd:COG1595 80 AIDHLRKRRRRREL-------LDELAEELPDE-----------AADPEEALEAEELLEALLAALER-LPPRQREVLVLrY 140
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 502819934 175 LDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLEIREIT 215
Cdd:COG1595 141 LEGLSYAEIAEILGISEGTVKSRLSRARKKLREALEEEGAL 181
|
|
| Sigma70_r2 |
pfam04542 |
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ... |
36-105 |
5.95e-15 |
|
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.
Pssm-ID: 427998 [Multi-domain] Cd Length: 71 Bit Score: 66.84 E-value: 5.95e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 36 LIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCITRQIITAIKTATR 105
Cdd:pfam04542 1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
|
|
| HTH_LUXR |
smart00421 |
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon |
160-205 |
4.07e-06 |
|
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
Pssm-ID: 197715 [Multi-domain] Cd Length: 58 Bit Score: 42.90 E-value: 4.07e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 502819934 160 AELLSDLERKVLVLYLDGQSYQEISEELNRHVKSIDNALQRVKRKL 205
Cdd:smart00421 1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKL 46
|
|
| LuxR_C_like |
cd06170 |
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ... |
163-205 |
8.45e-05 |
|
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.
Pssm-ID: 99777 [Multi-domain] Cd Length: 57 Bit Score: 39.05 E-value: 8.45e-05
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 502819934 163 LSDLERKVLVLYLDGQSYQEISEELNRHVKSIDNALQRVKRKL 205
Cdd:cd06170 1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKL 43
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08295 |
PRK08295 |
RNA polymerase sporulation sigma factor SigH; |
8-215 |
9.39e-133 |
|
RNA polymerase sporulation sigma factor SigH;
Pssm-ID: 181361 [Multi-domain] Cd Length: 208 Bit Score: 371.16 E-value: 9.39e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 8 KLHAHFEQQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAF 87
Cdd:PRK08295 1 LRMKDYDELEDEELVELARSGDKEALEYLIEKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDYDKDKLSSFKSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 88 AELCITRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLMDVISGTKVANPEELLINREKFDDIELKMAELLSDLE 167
Cdd:PRK08295 81 AELCITRQIITAIKTANRQKHIPLNSYVSLDKPIYDEESDRTLLDVISEAKVTDPEELIISKEELEDIEEKIEELLSELE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 502819934 168 RKVLVLYLDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLEIREIT 215
Cdd:PRK08295 161 KEVLELYLDGKSYQEIAEELNRHVKSIDNALQRVKRKLEKYLENREIT 208
|
|
| spore_sigH |
TIGR02859 |
RNA polymerase sigma-H factor; Members of this protein family are RNA polymerase sigma-H ... |
13-210 |
7.16e-123 |
|
RNA polymerase sigma-H factor; Members of this protein family are RNA polymerase sigma-H factor for sporulation in endospore-forming bacteria. This protein is also called Sigma-30 and SigH. Although rather close homologs in Listeria score well against this model, Listeria does not form spores and the role of the related sigma factor in that genus is in doubt. [Transcription, Transcription factors, Cellular processes, Sporulation and germination]
Pssm-ID: 131906 [Multi-domain] Cd Length: 198 Bit Score: 346.02 E-value: 7.16e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 13 FEQQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCI 92
Cdd:TIGR02859 1 FKQLEDEEIVELARQGNTHALEYLINKYKNFVRAKARSYFLIGADKEDIIQEGMIGLYKAIRDFRPDKLSSFKAFAELCV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 93 TRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLMDVISGTKVANPEELLINREKFDDIELKMAELLSDLERKVLV 172
Cdd:TIGR02859 81 TRQIITAIKTATRQKHIPLNSYVSLNKPIYDEESDRTLLDVISGAKVTDPEELIISQEEYGDIESKMNELLSDLEWKVLQ 160
|
170 180 190
....*....|....*....|....*....|....*...
gi 502819934 173 LYLDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLE 210
Cdd:TIGR02859 161 SYLDGKSYQEIACDLNRHVKSIDNALQRVKRKLEKYLE 198
|
|
| RpoE |
COG1595 |
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ... |
16-215 |
3.97e-24 |
|
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase
Pssm-ID: 441203 [Multi-domain] Cd Length: 181 Bit Score: 94.29 E-value: 3.97e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 16 QEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDklTSFKAFAELCITRQ 95
Cdd:COG1595 2 SSDEELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGR--GSFRAWLYRIARNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 96 IITAIKTATRQKHIplnsyvsLDKPIYDEESDrtlmdvisgtkVANPEELLINREKFDDIELKMAElLSDLERKVLVL-Y 174
Cdd:COG1595 80 AIDHLRKRRRRREL-------LDELAEELPDE-----------AADPEEALEAEELLEALLAALER-LPPRQREVLVLrY 140
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 502819934 175 LDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLEIREIT 215
Cdd:COG1595 141 LEGLSYAEIAEILGISEGTVKSRLSRARKKLREALEEEGAL 181
|
|
| sigma70-ECF |
TIGR02937 |
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ... |
31-209 |
2.62e-23 |
|
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.
Pssm-ID: 274357 [Multi-domain] Cd Length: 158 Bit Score: 91.25 E-value: 2.62e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 31 DALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKltSFKAFAELCITRQIITAIKtatRQKHIP 110
Cdd:TIGR02937 1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEG--SFKAWLFRIARNLILDYLR---RKRRLR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 111 LNSYVSLDKPIYDEesdrtlmdvisgtkvaNPEELLINREKFDDIELKMAElLSDLERKVLVL-YLDGQSYQEISEELNR 189
Cdd:TIGR02937 76 RELDLLEELLDSDP----------------SPEEELEQEEEREALREALEK-LPEREREVLVLrYLEGLSYKEIAEILGI 138
|
170 180
....*....|....*....|
gi 502819934 190 HVKSIDNALQRVKRKLERYL 209
Cdd:TIGR02937 139 SVGTVKRRLKRARKKLRELL 158
|
|
| Sigma70_r2 |
pfam04542 |
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ... |
36-105 |
5.95e-15 |
|
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.
Pssm-ID: 427998 [Multi-domain] Cd Length: 71 Bit Score: 66.84 E-value: 5.95e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 36 LIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCITRQIITAIKTATR 105
Cdd:pfam04542 1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
|
|
| PRK09652 |
PRK09652 |
RNA polymerase sigma factor RpoE; Provisional |
22-210 |
4.32e-14 |
|
RNA polymerase sigma factor RpoE; Provisional
Pssm-ID: 236608 [Multi-domain] Cd Length: 182 Bit Score: 67.52 E-value: 4.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 22 VDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDklTSFKAFaelcITRqiI---T 98
Cdd:PRK09652 1 VERVQRGDRAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRGG--AAFYTW----LYR--IarnT 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 99 AIKTATRQKHIPLNSYVSLDKPIYDEESDRTlmdvisgTKVANPEELLINREKFDDIELKMAELLSDLeRKVLVL-YLDG 177
Cdd:PRK09652 73 AINYLRKQGRRPPASDVDAEEAEDFDLADAL-------RDISTPENELLSAELEQRVRAAIESLPEEL-RTAITLrEIEG 144
|
170 180 190
....*....|....*....|....*....|....*..
gi 502819934 178 QSYQEISEELN---RHVKS-IDNALQRVKRKLERYLE 210
Cdd:PRK09652 145 LSYEEIAEIMGcpiGTVRSrIFRAREALRAKLQPLLD 181
|
|
| FliA |
COG1191 |
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ... |
26-207 |
4.82e-12 |
|
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase
Pssm-ID: 440804 [Multi-domain] Cd Length: 236 Bit Score: 62.92 E-value: 4.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 26 HKGDIDALEYLIHKYKNFVRAKARSYFL-IGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCITRQII------- 97
Cdd:COG1191 10 QEGDEEAREELIEEYLPLVKKIASRLAGrLPAELDDLIQVGLIGLIEAIDRFDPSKGVSFETYAVPRIRGAILdylrded 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 98 ----------TAIKTATR---QKH--------------IPLNSY------------VSLDKPIYDEESdrtLMDVIsgtK 138
Cdd:COG1191 90 wvprsvrelaRKIEEAIEeleQELgreptdeeiaeelgISLEEVqealeaanayqlLSLDEPLEDGDD---LLDLL---E 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502819934 139 VANPEELLINREKFDDIElKMAELLSDLERKVLVL-YLDGQSYQEISEELNRHVKSI----DNALQRVKRKLER 207
Cdd:COG1191 164 SGDPEEELEHEELREALA-EAIEQLPERERLVLSLyYFEELTLKEIAEVLGVSESRVsrlhKKALARLREYLKE 236
|
|
| algU |
PRK11923 |
RNA polymerase sigma factor AlgU; Provisional |
15-210 |
2.28e-09 |
|
RNA polymerase sigma factor AlgU; Provisional
Pssm-ID: 171347 [Multi-domain] Cd Length: 193 Bit Score: 54.81 E-value: 2.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 15 QQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDkltsfKAFAELCITR 94
Cdd:PRK11923 4 QEEDQQLVERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDTAEAQDVAQEAFIKAYRALGNFRGD-----SAFYTWLYRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 95 QIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRtLMDvisgtkVANPEELLINREKFDDIELKMAELLSDLERKVLVLY 174
Cdd:PRK11923 79 AINTAKNHLVSRGRRPPDSDVSSEDAEFYDGDHA-LKD------IESPERALLRDEIEGTVHRTIQQLPEDLRTALTLRE 151
|
170 180 190
....*....|....*....|....*....|....*.
gi 502819934 175 LDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLE 210
Cdd:PRK11923 152 FDGLSYEDIASVMQCPVGTVRSRIFRAREAIDKALQ 187
|
|
| PRK08583 |
PRK08583 |
RNA polymerase sigma factor SigB; Validated |
28-110 |
2.12e-08 |
|
RNA polymerase sigma factor SigB; Validated
Pssm-ID: 236306 [Multi-domain] Cd Length: 257 Bit Score: 52.77 E-value: 2.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 28 GDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCITRQIITAIKTATRQK 107
Cdd:PRK08583 26 QDEEAQEKLVKHYKNLVESLAYKYSKGQSHHEDLVQVGMVGLLGAIRRYDPSFGRSFEAFAVPTIIGEIKRYLRDKTWSV 105
|
...
gi 502819934 108 HIP 110
Cdd:PRK08583 106 HVP 108
|
|
| PRK05803 |
PRK05803 |
RNA polymerase sporulation sigma factor SigK; |
16-173 |
5.11e-08 |
|
RNA polymerase sporulation sigma factor SigK;
Pssm-ID: 180266 [Multi-domain] Cd Length: 233 Bit Score: 51.48 E-value: 5.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 16 QEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCITRQ 95
Cdd:PRK05803 34 EEERKYLELMKEGDEEARNILIERNLRLVAHIVKKFENTGEDVDDLISIGTIGLIKAIESFDAGKGTKLATYAARCIENE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 96 IITAIKTATRQKhiplnSYVSLDKPI-YDEE-SDRTLMDVISgtkvANPEELLinrekfDDIELKMAE--------LLSD 165
Cdd:PRK05803 114 ILMHLRNLKKTK-----KEVSLQDPIgVDKEgNEISLIDILG----SEEDDVI------EQVELKMEVeklykkidILDE 178
|
....*...
gi 502819934 166 LERKVLVL 173
Cdd:PRK05803 179 REKEVIEM 186
|
|
| PRK13919 |
PRK13919 |
putative RNA polymerase sigma E protein; Provisional |
14-211 |
6.12e-08 |
|
putative RNA polymerase sigma E protein; Provisional
Pssm-ID: 184395 [Multi-domain] Cd Length: 186 Bit Score: 50.68 E-value: 6.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 14 EQQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFrEDKLTSFKAFAeLCIT 93
Cdd:PRK13919 6 ESLSDEALLALVARGEEEALRALFRRYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEF-DPRRGSARAWL-LALA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 94 RQiiTAIKTATRQKHIPLnsyvsldkPIYDEESDRTLMDVisgtkvanPEELLINREKFDDIELKMA-ELLSDLERKVL- 171
Cdd:PRK13919 84 HH--AAVDHVRRRAARPQ--------PLEPDEREPEAFDL--------PGPGLDEEGHLDRTRLGRAlKALSPEERRVIe 145
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 502819934 172 VLYLDGQSYQEISEELNRHVKSIDNalqRVKRKLERYLEI 211
Cdd:PRK13919 146 VLYYQGYTHREAAQLLGLPLGTLKT---RARRALSRLKEV 182
|
|
| PRK11924 |
PRK11924 |
RNA polymerase sigma factor; Provisional |
26-207 |
2.31e-07 |
|
RNA polymerase sigma factor; Provisional
Pssm-ID: 183384 [Multi-domain] Cd Length: 179 Bit Score: 49.20 E-value: 2.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 26 HKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKltSFKAFAeLCITRQIITAI--KTA 103
Cdd:PRK11924 8 ATGDKEAFSELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGKG--SARTWL-LTIARNVCYDLlrRRR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 104 TRQkhiplnsyvsldkpiYDEESDrtLMDVISGTKVANPEELLINREKFDDIElKMAELLSDLERKVLVL-YLDGQSYQE 182
Cdd:PRK11924 85 REK---------------AVLSDD--ALEPEFAETAETPEAALLAKDDLARID-RCLDALPVKQREVFLLrYVEGLSYRE 146
|
170 180
....*....|....*....|....*....
gi 502819934 183 ISEELN---RHVKS-IDNALQRVKRKLER 207
Cdd:PRK11924 147 IAEILGvpvGTVKSrLRRARQLLRECLEA 175
|
|
| Sigma70_r4_2 |
pfam08281 |
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ... |
157-205 |
3.85e-07 |
|
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.
Pssm-ID: 400535 [Multi-domain] Cd Length: 54 Bit Score: 45.52 E-value: 3.85e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 502819934 157 LKMAELLSDLERKVLVL-YLDGQSYQEISEELNRHVKSIDNALQRVKRKL 205
Cdd:pfam08281 5 LRALEELPPRQREVFLLrYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
|
|
| RpoD |
COG0568 |
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ... |
115-188 |
3.10e-06 |
|
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase
Pssm-ID: 440334 [Multi-domain] Cd Length: 268 Bit Score: 46.59 E-value: 3.10e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502819934 115 VSLDKPIyDEESDRTLMDVISGTKVANPEELLINREKFDDIELKMAElLSDLERKVLVLY---LDGQSY--QEISEELN 188
Cdd:COG0568 161 VSLDAPV-GDDEDSELGDLLEDEEAPSPEEALEEELLREELREALDT-LTEREREILRLRfglDDGEPHtlEEIGKEFG 237
|
|
| HTH_LUXR |
smart00421 |
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon |
160-205 |
4.07e-06 |
|
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
Pssm-ID: 197715 [Multi-domain] Cd Length: 58 Bit Score: 42.90 E-value: 4.07e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 502819934 160 AELLSDLERKVLVLYLDGQSYQEISEELNRHVKSIDNALQRVKRKL 205
Cdd:smart00421 1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKL 46
|
|
| CitB |
COG2197 |
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ... |
153-206 |
7.90e-06 |
|
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];
Pssm-ID: 441799 [Multi-domain] Cd Length: 131 Bit Score: 43.73 E-value: 7.90e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 502819934 153 DDIELkMAELLSDLERKVLVLYLDGQSYQEISEELNRHVKSIDNALQRVKRKLE 206
Cdd:COG2197 61 DGLEA-LRRLLTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLG 113
|
|
| PRK08311 |
PRK08311 |
RNA polymerase sigma factor SigI; |
14-156 |
1.11e-05 |
|
RNA polymerase sigma factor SigI;
Pssm-ID: 236233 [Multi-domain] Cd Length: 237 Bit Score: 44.86 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 14 EQQEDETVVDLVHKGDIDALEYLIHKYKNFVrAKARSYFL---IGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAEL 90
Cdd:PRK08311 1 RKKSLEDILEKIKNGDEELREELIEEYKPFI-AKVVSSVCgryIDWENDDELSIGLIAFNEAIDSYDEEKGKSFLSFAEL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502819934 91 CITRQIITAIKTATRQKHIPLNSyvsldkpiYDEESDRTLMDVISgtKVANPEELLINREKFDDIE 156
Cdd:PRK08311 80 VIKRRLIDYFRKESKHNLVLSNS--------DEEDEEENDIEIEL--SLEEYQEEEENEERREEIE 135
|
|
| CsgD |
COG2771 |
DNA-binding transcriptional regulator, CsgD family [Transcription]; |
43-205 |
1.93e-05 |
|
DNA-binding transcriptional regulator, CsgD family [Transcription];
Pssm-ID: 442052 [Multi-domain] Cd Length: 188 Bit Score: 43.59 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 43 FVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAELCITRQIITAIKTATRQKHIPLNSYVSLDKPIY 122
Cdd:COG2771 7 ALLLLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLLLLALLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 123 DEESDRTLMDVISGTKVANPEELLINREKFDDIELKMAEL-LSDLERKVLVLYLDGQSYQEISEELNRHVKSIDNALQRV 201
Cdd:COG2771 87 LLALLALLAALLARLAALLLALALAALLLAALARLLARAPgLTPREREVLRLLAEGLTLKEIARILGISERTVRTHLKRI 166
|
....
gi 502819934 202 KRKL 205
Cdd:COG2771 167 YRKL 170
|
|
| PRK12524 |
PRK12524 |
RNA polymerase sigma factor; Provisional |
18-210 |
2.46e-05 |
|
RNA polymerase sigma factor; Provisional
Pssm-ID: 183573 [Multi-domain] Cd Length: 196 Bit Score: 43.34 E-value: 2.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 18 DETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFR--EDKLTS--FKAFAELCIT 93
Cdd:PRK12524 13 DEALLVLYANGDPAAARALTLRLAPRALAVATRVLGDRAEAEDVTQEAMLRLWRIAPDWRqgEARVSTwlYRVVCNLCTD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 94 RqiitaiKTATRQKHIplnsyvsldkpiyDEESDRTLMDVISGTkvanpEELLINREKFDDIELKMAElLSDLERKVLVL 173
Cdd:PRK12524 93 R------LRRRRRASV-------------DLDDAPEPADAAPGA-----EEALIEGDRMRALDAALAA-LPERQRQAVVL 147
|
170 180 190
....*....|....*....|....*....|....*...
gi 502819934 174 -YLDGQSYQEISEELNRHVKSIDNALQRVKRKLERYLE 210
Cdd:PRK12524 148 rHIEGLSNPEIAEVMEIGVEAVESLTARGKRALAALLA 185
|
|
| PRK09641 |
PRK09641 |
RNA polymerase sigma factor SigW; Provisional |
22-210 |
8.27e-05 |
|
RNA polymerase sigma factor SigW; Provisional
Pssm-ID: 182012 [Multi-domain] Cd Length: 187 Bit Score: 41.99 E-value: 8.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 22 VDLVHKGDIDALEYLIHKYKNFVRAKArsYFLIG--ADREDIVQEGMIGLYKAIRDFREDKLTS---FKAFAELCITRqi 96
Cdd:PRK09641 9 IKQVKKGDQNAFAELVDLYKDKIYQLC--YRMLGnrHEAEDAAQEAFIRAYVNIDSYDINRKFStwlYRIATNLTIDR-- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 97 itaiktaTRQKhiplNSYVSLDKPIYDEEsDRTLMDVISgTKVANPEELLINREKFDDIELKMAELlSDLERKVLVL-YL 175
Cdd:PRK09641 85 -------LRKR----KPDYYLDAEVAGTE-GLTMYSQLA-ADDALPEEQVVSLELQETIQEAILQL-PEKYRTVIVLkYI 150
|
170 180 190
....*....|....*....|....*....|....*
gi 502819934 176 DGQSYQEISEELNRHVKSIDNALQRVKRKLERYLE 210
Cdd:PRK09641 151 EDLSLKEISEILDLPVGTVKTRIHRGREALRKQLR 185
|
|
| LuxR_C_like |
cd06170 |
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ... |
163-205 |
8.45e-05 |
|
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.
Pssm-ID: 99777 [Multi-domain] Cd Length: 57 Bit Score: 39.05 E-value: 8.45e-05
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 502819934 163 LSDLERKVLVLYLDGQSYQEISEELNRHVKSIDNALQRVKRKL 205
Cdd:cd06170 1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKL 43
|
|
| PRK06811 |
PRK06811 |
RNA polymerase factor sigma-70; Validated |
27-205 |
1.40e-04 |
|
RNA polymerase factor sigma-70; Validated
Pssm-ID: 180707 [Multi-domain] Cd Length: 189 Bit Score: 41.08 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 27 KGDIDALEYLIHKYKNFVRAKARSYFLIGADREDI---VQEGMIGLYKAIRDFREDKlTSFKAFAeLCITR-QIITAIKT 102
Cdd:PRK06811 14 KKNEKALEFIVDTYGNLVKKIVHKVLGTVNYSQLIeecVNDIFLSIWNNIDKFDEEK-GSFKKWI-AAISKyKAIDYKRK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 103 ATRQKHIplnsyVSLDKpIYDEESDRTlmdvisgtkvanpEELLINREKFDDIeLKMAELLSDLERKVLVL-YLDGQSYQ 181
Cdd:PRK06811 92 LTKNNEI-----DSIDE-FILISEESI-------------ENEIILKENKEEI-LKLINDLEKLDREIFIRrYLLGEKIE 151
|
170 180
....*....|....*....|....
gi 502819934 182 EISEELNRHVKSIDNALQRVKRKL 205
Cdd:PRK06811 152 EIAKKLGLTRSAIDNRLSRGRKKL 175
|
|
| Sig70_bacteroi1 |
TIGR02985 |
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ... |
31-205 |
2.04e-04 |
|
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.
Pssm-ID: 274376 [Multi-domain] Cd Length: 161 Bit Score: 40.24 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 31 DALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKaIRDFREDkLTSFKAFaelcitrqIITAIKTAT----RQ 106
Cdd:TIGR02985 1 EAFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWE-NRETLEI-SESIKAY--------LFTIVKNRClnylRH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 107 KHIPLNSYVSLDKPIYDEESDrtlmdvisgtkvANPEELLINREKFDDIELKMAElLSDLERKVLVL-YLDGQSYQEISE 185
Cdd:TIGR02985 71 KQVEEKYQEELAEIEERELSE------------ADPEEELEAKELEEIIEEAIEK-LPEQCREIFILsRFEGLSNKEIAE 137
|
170 180
....*....|....*....|
gi 502819934 186 ELNRHVKSIDNALQRVKRKL 205
Cdd:TIGR02985 138 ELGISVKTVEYHITKALKFL 157
|
|
| PRK06288 |
PRK06288 |
RNA polymerase sigma factor WhiG; Reviewed |
14-187 |
2.67e-04 |
|
RNA polymerase sigma factor WhiG; Reviewed
Pssm-ID: 235770 [Multi-domain] Cd Length: 268 Bit Score: 40.83 E-value: 2.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 14 EQQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKArSYFLIG----ADREDIVQEGMIGLYKAIRDFREDKLTSFKAFAE 89
Cdd:PRK06288 14 QQDETELWREYKKTGDPKIREYLILKYSPLVKYVA-GRIAVGmpqnVEFDDLVSYGVFGLIDAIEKFDPEREIKFKTYAV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 90 LCI---------------------TRQIITAI--------KTATRQ-----------------KHIPLNSYVSLDKPIY- 122
Cdd:PRK06288 93 TRIrgaifdelrsidwiprsvrqkARQIERAIamlearlgRTPSDEeiadelgisleeynsllSKLSGTSVVSLNDLWFg 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502819934 123 DEESDR-TLMDVISGTKVANPEElLINREkfdDIELKMAELLSDL---ERKVLVL-YLDGQSYQEISEEL 187
Cdd:PRK06288 173 GDEGDEvSLMDTLESPAALNPDE-IAERE---EIKRVIVEAIKTLperEKKVLILyYYEDLTLKEIGKVL 238
|
|
| PRK11922 |
PRK11922 |
RNA polymerase sigma factor; Provisional |
16-80 |
3.05e-03 |
|
RNA polymerase sigma factor; Provisional
Pssm-ID: 237024 [Multi-domain] Cd Length: 231 Bit Score: 37.64 E-value: 3.05e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 502819934 16 QEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDK 80
Cdd:PRK11922 15 ASDRELVARVLAGDEAAFEALMRRHNRRLYRTARAILRNDAEAEDVVQEAYLRAFRALGTFRGDA 79
|
|
| PRK06596 |
PRK06596 |
RNA polymerase factor sigma-32; Reviewed |
15-84 |
4.30e-03 |
|
RNA polymerase factor sigma-32; Reviewed
Pssm-ID: 235838 [Multi-domain] Cd Length: 284 Bit Score: 37.08 E-value: 4.30e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502819934 15 QQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDFREDK---LTSF 84
Cdd:PRK06596 32 EEEYMLAKRLREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLIQEGNIGLMKAVKRFDPEVgvrLVSF 104
|
|
| PRK05572 |
PRK05572 |
RNA polymerase sporulation sigma factor, SigF/SigG family; |
11-76 |
7.45e-03 |
|
RNA polymerase sporulation sigma factor, SigF/SigG family;
Pssm-ID: 180137 [Multi-domain] Cd Length: 252 Bit Score: 36.49 E-value: 7.45e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502819934 11 AHFEQQEDETVVDLVHKGDIDALEYLIHKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDF 76
Cdd:PRK05572 12 PQLKDEENKELIKKSQDGDQEARDTLVEKNLRLVWSVVQRFLNRGYEPDDLFQIGCIGLLKAVDKF 77
|
|
|