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Conserved domains on  [gi|502826623|ref|WP_013061599|]
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cyclopropane-fatty-acyl-phospholipid synthase family protein [Salinibacter ruber]

Protein Classification

SAM-dependent methyltransferase( domain architecture ID 11454891)

SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  2.20.25.110
EC:  2.1.-.-
Gene Ontology:  GO:0032259|GO:0008757|GO:1904047|GO:0008168
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 61-165 1.53e-16

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


:

Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 73.43  E-value: 1.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  61 VDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEADISEA- 139
Cdd:COG2230   40 LDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDLPADGQf 119

                         90       100       110
                 ....*....|....*....|....*....|.
gi 502826623 140 -TVVTLYLLPSVNQKLRPILFEQ----LSPG 165
Cdd:COG2230  120 dAIVSIGMFEHVGPENYPAYFAKvarlLKPG 150
 
Name Accession Description Interval E-value
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 61-165 1.53e-16

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 73.43  E-value: 1.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  61 VDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEADISEA- 139
Cdd:COG2230   40 LDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDLPADGQf 119

                         90       100       110
                 ....*....|....*....|....*....|.
gi 502826623 140 -TVVTLYLLPSVNQKLRPILFEQ----LSPG 165
Cdd:COG2230  120 dAIVSIGMFEHVGPENYPAYFAKvarlLKPG 150
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 75-165 6.38e-13

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 62.20  E-value: 6.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623   75 VLyDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVAdlVEFRQGDLFEADISEAT---VVTLYLLPSVN 151
Cdd:pfam13649   1 VL-DLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLN--VEFVQGDAEDLPFPDGSfdlVVSSGVLHHLP 77

                          90
                  ....*....|....*...
gi 502826623  152 QKLRPILFEQ----LSPG 165
Cdd:pfam13649  78 DPDLEAALREiarvLKPG 95
arsM PRK11873
arsenite methyltransferase;
65-131 1.19e-10

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 59.19  E-value: 1.19e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502826623  65 LELADVDETDVLYDLGSGDGRIVIRAARTHGARG--VGIEIDPDLVKKARKNAKEAGVADlVEFRQGDL 131
Cdd:PRK11873  70 TALAELKPGETVLDLGSGGGFDCFLAARRVGPTGkvIGVDMTPEMLAKARANARKAGYTN-VEFRLGEI 137
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 76-138 3.72e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 55.13  E-value: 3.72e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502826623  76 LYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAkEAGVADLVEFRQGDLFEADISE 138
Cdd:cd02440    2 VLDLGCGTGALALALASGPGARVTGVDISPVALELARKAA-AALLADNVEVLKGDAEELPPEA 63
rumA TIGR00479
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ...
 58-131 8.63e-07

23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 129571 [Multi-domain]  Cd Length: 431  Bit Score: 48.28  E-value: 8.63e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502826623   58 KPVVDRMLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVADlVEFRQGDL 131
Cdd:TIGR00479 278 EKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAK-QAKSVVGVEGVPESVEKAQQNAELNGIAN-VTFYHGTL 349
rADc smart00650
Ribosomal RNA adenine dimethylases;
60-113 5.39e-05

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 42.11  E-value: 5.39e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 502826623    60 VVDRMLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARK 113
Cdd:smart00650   1 VIDKIVRAANLRPGDTVLEIGPGKGALTEELLE-RAKRVTAIEIDPRLAPRLRE 53
 
Name Accession Description Interval E-value
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 61-165 1.53e-16

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 73.43  E-value: 1.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  61 VDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEADISEA- 139
Cdd:COG2230   40 LDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDLPADGQf 119

                         90       100       110
                 ....*....|....*....|....*....|.
gi 502826623 140 -TVVTLYLLPSVNQKLRPILFEQ----LSPG 165
Cdd:COG2230  120 dAIVSIGMFEHVGPENYPAYFAKvarlLKPG 150
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
55-142 2.57e-13

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 65.70  E-value: 2.57e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  55 PTPKPVVDRMLELA----DVDETDVLyDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVAdlVEFRQGD 130
Cdd:COG2263   25 PTPAELAAELLHLAylrgDIEGKTVL-DLGCGTGMLAIGAALLGAKKVVGVDIDPEALEIARENAERLGVR--VDFIRAD 101

                         90
                 ....*....|....
gi 502826623 131 LFEADISE--ATVV 142
Cdd:COG2263  102 VTRIPLGGsvDTVV 115
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 53-165 6.00e-13

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 64.55  E-value: 6.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  53 YVPTPKPVVDRMLELADVDETDVLY-DLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADlVEFRQGDL 131
Cdd:COG0500    6 YSDELLPGLAALLALLERLPKGGRVlDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAAKAGLGN-VEFLVADL 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 502826623 132 FEADISEAT---VVTL-----YLLPSVNQKLRPILFEQLSPG 165
Cdd:COG0500   85 AELDPLPAEsfdLVVAfgvlhHLPPEEREALLRELARALKPG 126
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 75-165 6.38e-13

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 62.20  E-value: 6.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623   75 VLyDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVAdlVEFRQGDLFEADISEAT---VVTLYLLPSVN 151
Cdd:pfam13649   1 VL-DLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLN--VEFVQGDAEDLPFPDGSfdlVVSSGVLHHLP 77

                          90
                  ....*....|....*...
gi 502826623  152 QKLRPILFEQ----LSPG 165
Cdd:pfam13649  78 DPDLEAALREiarvLKPG 95
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 75-187 2.33e-12

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 62.05  E-value: 2.33e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623   75 VLYDLGSGDGRIVIRAARTHGARG--VGIEIDPDLVKKARKNAKEAGVADlVEFRQGDLFEADISEAT----VV----TL 144
Cdd:pfam13847   6 RVLDLGCGTGHLSFELAEELGPNAevVGIDISEEAIEKARENAQKLGFDN-VEFEQGDIEELPELLEDdkfdVVisncVL 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 502826623  145 YLLPSVNQKLRpILFEQLSPGTPVVSHDFDMGRWTPDRTVDLE 187
Cdd:pfam13847  85 NHIPDPDKVLQ-EILRVLKPGGRLIISDPDSLAELPAHVKEDS 126
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 61-134 4.70e-12

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 63.66  E-value: 4.70e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502826623  61 VDRMLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVADlVEFRQGDLFEA 134
Cdd:COG2265  222 YAAALEWLDLTGGERVLDLYCGVGTFALPLAR-RAKKVIGVEIVPEAVEDARENARLNGLKN-VEFVAGDLEEV 293
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 62-141 1.31e-11

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 59.62  E-value: 1.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  62 DRMLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVAdlVEFRQGDLFEADISEATV 141
Cdd:COG2226   12 EALLAALGLRPGARVLDLGCGTGRLALALAE-RGARVTGVDISPEMLELARERAAEAGLN--VEFVVGDAEDLPFPDGSF 88
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 61-165 8.92e-11

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 57.33  E-value: 8.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  61 VDRMLELADVDETDVLyDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGvadlVEFRQGDLFEADISEAT 140
Cdd:COG2227   14 LAALLARLLPAGGRVL-DVGCGTGRLALALAR-RGADVTGVDISPEALEIARERAAELN----VDFVQGDLEDLPLEDGS 87

                         90       100       110
                 ....*....|....*....|....*....|.
gi 502826623 141 --VVT----LYLLPSVNQKLRpILFEQLSPG 165
Cdd:COG2227   88 fdLVIcsevLEHLPDPAALLR-ELARLLKPG 117
UPF0020 pfam01170
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated ...
 64-143 1.10e-10

Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.


Pssm-ID: 395932 [Multi-domain]  Cd Length: 184  Bit Score: 58.14  E-value: 1.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623   64 MLELADVDETDVLYDLGSGDGRIVIRAA-----RTHGARG-------VGIEIDPDLVKKARKNAKEAGVADLVEFRQGD- 130
Cdd:pfam01170  20 MVNLAGWKPGDPLLDPMCGSGTILIEAAlmganIAPGKFDarvraplYGSDIDRRMVQGARLNAENAGVGDLIEFVQADa 99

                          90
                  ....*....|....*
gi 502826623  131 --LFEADISEATVVT 143
Cdd:pfam01170 100 adLPLLEGSVDVIVT 114
arsM PRK11873
arsenite methyltransferase;
65-131 1.19e-10

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 59.19  E-value: 1.19e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502826623  65 LELADVDETDVLYDLGSGDGRIVIRAARTHGARG--VGIEIDPDLVKKARKNAKEAGVADlVEFRQGDL 131
Cdd:PRK11873  70 TALAELKPGETVLDLGSGGGFDCFLAARRVGPTGkvIGVDMTPEMLAKARANARKAGYTN-VEFRLGEI 137
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 76-138 3.72e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 55.13  E-value: 3.72e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502826623  76 LYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAkEAGVADLVEFRQGDLFEADISE 138
Cdd:cd02440    2 VLDLGCGTGALALALASGPGARVTGVDISPVALELARKAA-AALLADNVEVLKGDAEELPPEA 63
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 60-134 3.95e-10

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 57.85  E-value: 3.95e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502826623  60 VVDRMLELADVDETDVLYDLGSGDGRIVIRAARTH-GARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEA 134
Cdd:COG2890  100 LVELALALLPAGAPPRVLDLGTGSGAIALALAKERpDARVTAVDISPDALAVARRNAERLGLEDRVRFLQGDLFEP 175
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 67-133 4.32e-09

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 54.38  E-value: 4.32e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 502826623  67 LADVDETDVLYDLGSGDGRIVIR-AARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFE 133
Cdd:COG4123   32 FAPVKKGGRVLDLGTGTGVIALMlAQRSPGARITGVEIQPEAAELARRNVALNGLEDRITVIHGDLKE 99
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 60-131 1.19e-08

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 53.30  E-value: 1.19e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502826623  60 VVDRMLELADVDETDVLyDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDL 131
Cdd:PRK07580  52 VLSWLPADGDLTGLRIL-DAGCGVGSLSIPLAR-RGAKVVASDISPQMVEEARERAPEAGLAGNITFEVGDL 121
RlmL COG0116
23S rRNA G2445 N2-methylase RlmL [Translation, ribosomal structure and biogenesis]; 23S rRNA ...
 89-133 1.51e-08

23S rRNA G2445 N2-methylase RlmL [Translation, ribosomal structure and biogenesis]; 23S rRNA G2445 N2-methylase RlmL is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 439886 [Multi-domain]  Cd Length: 369  Bit Score: 53.57  E-value: 1.51e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 502826623  89 RAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFE 133
Cdd:COG0116  244 RIKRDPPLPIFGSDIDPRAIEAARENAERAGVADLIEFEQADFRD 288
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
70-138 4.91e-08

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 51.58  E-value: 4.91e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  70 VDETDVLYDLGSGDGRIVIRAARtHGARGV-GIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEADISE 138
Cdd:COG4076   33 VKPGDVVLDIGTGSGLLSMLAAR-AGAKKVyAVEVNPDIAAVARRIIAANGLSDRITVINADATDLDLPE 101
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
77-165 1.08e-07

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 48.28  E-value: 1.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  77 YDLGSGDGRIVIR-AARTHGARGVGIEIDPDLVKKARKNAKEagvadlVEFRQGDLFEADISE-ATVV----TLYLLPSV 150
Cdd:COG4106    6 LDLGCGTGRLTALlAERFPGARVTGVDLSPEMLARARARLPN------VRFVVADLRDLDPPEpFDLVvsnaALHWLPDH 79

                         90
                 ....*....|....*
gi 502826623 151 nQKLRPILFEQLSPG 165
Cdd:COG4106   80 -AALLARLAAALAPG 93
PRK14968 PRK14968
putative methyltransferase; Provisional
 64-133 3.28e-07

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 48.36  E-value: 3.28e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 502826623  64 MLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVADL-VEFRQGDLFE 133
Cdd:PRK14968  15 LAENAVDKKGDRVLEVGTGSGIVAIVAAK-NGKKVVGVDINPYAVECAKCNAKLNNIRNNgVEVIRSDLFE 84
rlmL PRK11783
bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2)) ...
 100-131 3.66e-07

bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL;


Pssm-ID: 236981 [Multi-domain]  Cd Length: 702  Bit Score: 49.80  E-value: 3.66e-07
                         10        20        30
                 ....*....|....*....|....*....|..
gi 502826623 100 GIEIDPDLVKKARKNAKEAGVADLVEFRQGDL 131
Cdd:PRK11783 261 GSDIDPRVIQAARKNARRAGVAELITFEVKDV 292
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 64-141 6.35e-07

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 47.64  E-value: 6.35e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 502826623  64 MLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVADlVEFRQGDLFEADISEATV 141
Cdd:COG1041   18 LVNLAGAKEGDTVLDPFCGTGTILIEAGL-LGRRVIGSDIDPKMVEGARENLEHYGYED-ADVIRGDARDLPLADESV 93
rumA TIGR00479
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ...
 58-131 8.63e-07

23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 129571 [Multi-domain]  Cd Length: 431  Bit Score: 48.28  E-value: 8.63e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502826623   58 KPVVDRMLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVADlVEFRQGDL 131
Cdd:TIGR00479 278 EKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAK-QAKSVVGVEGVPESVEKAQQNAELNGIAN-VTFYHGTL 349
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
63-136 4.79e-06

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 45.93  E-value: 4.79e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502826623  63 RMLELADVDETDVLyDLGSGDGriV--IRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFE---ADI 136
Cdd:COG2264  140 EALEKLLKPGKTVL-DVGCGSG--IlaIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLLEdgpYDL 215
rumA PRK13168
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
61-139 6.92e-06

23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;


Pssm-ID: 237291 [Multi-domain]  Cd Length: 443  Bit Score: 45.92  E-value: 6.92e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  61 VDRMLELADVDETD-VLyDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGVADlVEFRQGDLFEaDISEA 139
Cdd:PRK13168 286 VARALEWLDPQPGDrVL-DLFCGLGNFTLPLAR-QAAEVVGVEGVEAMVERARENARRNGLDN-VTFYHANLEE-DFTDQ 361
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 99-130 8.42e-06

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 44.40  E-value: 8.42e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 502826623  99 VGIEIDPDLVKKARKNAKEAGVADLVEFRQGD 130
Cdd:COG4122   45 TTIEIDPERAAIARENFARAGLADRIRLILGD 76
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 78-141 3.42e-05

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 41.11  E-value: 3.42e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502826623   78 DLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARKNAKEAGvadlVEFRQGDLFEADISEATV 141
Cdd:pfam08241   2 DVGCGTGLLTELLAR-LGARVTGVDISPEMLELAREKAPREG----LTFVVGDAEDLPFPDNSF 60
rADc smart00650
Ribosomal RNA adenine dimethylases;
60-113 5.39e-05

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 42.11  E-value: 5.39e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 502826623    60 VVDRMLELADVDETDVLYDLGSGDGRIVIRAARtHGARGVGIEIDPDLVKKARK 113
Cdd:smart00650   1 VIDKIVRAANLRPGDTVLEIGPGKGALTEELLE-RAKRVTAIEIDPRLAPRLRE 53
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
29-130 5.47e-05

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 42.36  E-value: 5.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623   29 QTDTTAET--TIPGLKMPPEQESDVPYVPTPKPV-----------VDRMLELADVDETDVLYDLGSGDGRIVIRAARTHG 95
Cdd:pfam01135  17 KSDKVAEAmlAVDREEFVPESFKSYAYEDIPLSIgygqtisaphmHAMMLELLELKPGMRVLEIGSGSGYLTACFARMVG 96

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 502826623   96 ARG--VGIEIDPDLVKKARKNAKEAGvADLVEFRQGD 130
Cdd:pfam01135  97 EVGrvVSIEHIPELVEIARRNLEKLG-LENVIVVVGD 132
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 78-144 8.30e-05

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 40.04  E-value: 8.30e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623   78 DLGSGDGRIVIR-AARTHGARGVGIEIDPDLVKKARK--NAKEAGVADLVEFRQGDLFEADISEATVVTL 144
Cdd:pfam08242   2 EIGCGTGTLLRAlLEALPGLEYTGLDISPAALEAARErlAALGLLNAVRVELFQLDLGELDPGSFDVVVA 71
PRK14966 PRK14966
unknown domain/N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase fusion protein; ...
 52-136 8.94e-05

unknown domain/N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase fusion protein; Provisional


Pssm-ID: 184930 [Multi-domain]  Cd Length: 423  Bit Score: 42.38  E-value: 8.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  52 PYVPTPKPVVDRMLE--LADVDETDVLYDLGSGDGRIVIRAARTHGARGV-GIEIDPDLVKKARKNAKEAGVAdlVEFRQ 128
Cdd:PRK14966 229 PNVLIPRPETEHLVEavLARLPENGRVWDLGTGSGAVAVTVALERPDAFVrASDISPPALETARKNAADLGAR--VEFAH 306


                 ....*...
gi 502826623 129 GDLFEADI 136
Cdd:PRK14966 307 GSWFDTDM 314
CMAS pfam02353
Mycolic acid cyclopropane synthetase; This family consist of ...
 61-127 9.57e-05

Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.


Pssm-ID: 396777 [Multi-domain]  Cd Length: 272  Bit Score: 41.93  E-value: 9.57e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 502826623   61 VDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFR 127
Cdd:pfam02353  50 LDLILDKLGLKPGMTLLDIGCGWGGLMRRAAERYDVNVVGLTLSKNQYKLARKRVAAEGLARKVEVL 116
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 64-134 9.78e-05

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 41.33  E-value: 9.78e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502826623  64 MLELADVDETDVLYDLGSGDGRIVIRAARTH-GARGVGIEIDPDLVKKARKNAKEAGVADlVEFRQGDLFEA 134
Cdd:COG2813   41 LLEHLPEPLGGRVLDLGCGYGVIGLALAKRNpEARVTLVDVNARAVELARANAAANGLEN-VEVLWSDGLSG 111
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 38-134 1.40e-04

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 41.32  E-value: 1.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  38 IPGLkmPPEQESDVPYVPTPKPVVdRMLEL--ADVDETDVLYDLGSGDGRIVIRAARTHGARG--VGIEIDPDLVKKARK 113
Cdd:PRK00377   7 IPGI--PDEEFERDEEIPMTKEEI-RALALskLRLRKGDMILDIGCGTGSVTVEASLLVGETGkvYAVDKDEKAINLTRR 83

                         90       100
                 ....*....|....*....|.
gi 502826623 114 NAKEAGVADLVEFRQGDLFEA 134
Cdd:PRK00377  84 NAEKFGVLNNIVLIKGEAPEI 104
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
63-136 1.48e-04

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 41.29  E-value: 1.48e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 502826623  63 RMLELADVDETDVLyDLGSGDGRIVIrAARTHGARGV-GIEIDPDLVKKARKNAKEAGVADLVEFRQGDLfEADI 136
Cdd:PRK00517 111 EALEKLVLPGKTVL-DVGCGSGILAI-AAAKLGAKKVlAVDIDPQAVEAARENAELNGVELNVYLPQGDL-KADV 182
ksgA PRK14896
16S ribosomal RNA methyltransferase A;
60-142 3.35e-04

16S ribosomal RNA methyltransferase A;


Pssm-ID: 237852 [Multi-domain]  Cd Length: 258  Bit Score: 40.27  E-value: 3.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  60 VVDRMLELADVDETDVLYDLGSGDGRIVIRAARThGARGVGIEIDPDLVKKARKNAKEAGVADLVEfrqGDLFEADISEA 139
Cdd:PRK14896  17 VVDRIVEYAEDTDGDPVLEIGPGKGALTDELAKR-AKKVYAIELDPRLAEFLRDDEIAAGNVEIIE---GDALKVDLPEF 92


                 ...
gi 502826623 140 TVV 142
Cdd:PRK14896  93 NKV 95
RsmA COG0030
16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase ...
 60-138 4.37e-04

16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) [Translation, ribosomal structure and biogenesis]; 16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 439801 [Multi-domain]  Cd Length: 270  Bit Score: 40.11  E-value: 4.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  60 VVDRMLELADVDETDVLYDLGSGDG----RIVIRAARThgargVGIEIDPDLVKKARKNAKEAGVADLVEfrqGDLFEAD 135
Cdd:COG0030   25 IIRRIVDAAGITPGDTVLEIGPGLGaltrALLERAARV-----TAVEIDRRLAAILRETFAAYPNLTVIE---GDALKVD 96


                 ...
gi 502826623 136 ISE 138
Cdd:COG0030   97 LPA 99
DOT1 pfam08123
Histone methylation protein DOT1; The DOT1 domain regulates gene expression by methylating ...
 64-170 4.48e-04

Histone methylation protein DOT1; The DOT1 domain regulates gene expression by methylating histone H3. H3 methylation by DOT1 has been shown to be required for the DNA damage checkpoint in yeast.


Pssm-ID: 149273  Cd Length: 205  Bit Score: 39.59  E-value: 4.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623   64 MLELADVDETDVLYDLGSGDGRIVIRAARTHGAR-GVGIEIDPDLVKKARKNAKEA-------GVADL-VEFRQGDLFEA 134
Cdd:pfam08123  34 VLDKCNLGPQDVFVDLGSGVGNCVLQAALEFGCKlSFGCEIMDNASNLAELQDEEFkkrcklfGKKLGkIEFIRGSFLDN 113

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 502826623  135 D-----ISEATVVTL--YLL-PSVNQKLRPIlFEQLSPGTPVVS 170
Cdd:pfam08123 114 ErveeiIPEADVILVnnFAFdPELNLQLKEM-LQDLKDGCKIIS 156
CobL COG2242
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ...
 74-123 5.85e-04

Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 441843 [Multi-domain]  Cd Length: 403  Bit Score: 39.76  E-value: 5.85e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 502826623  74 DVLYDLGSGDGRIVIRAARTH-GARGVGIEIDPDLVKKARKNAKEAGVADL 123
Cdd:COG2242  249 DVLWDIGAGSGSVSIEAARLApGGRVYAIERDPERAALIRANARRFGVPNV 299
PTZ00338 PTZ00338
dimethyladenosine transferase-like protein; Provisional
 60-136 6.76e-04

dimethyladenosine transferase-like protein; Provisional


Pssm-ID: 240367 [Multi-domain]  Cd Length: 294  Bit Score: 39.60  E-value: 6.76e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 502826623  60 VVDRMLELADVDETDVLYDLGSGDGRIVIRAARThgARGV-GIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEADI 136
Cdd:PTZ00338  24 VLDKIVEKAAIKPTDTVLEIGPGTGNLTEKLLQL--AKKViAIEIDPRMVAELKKRFQNSPLASKLEVIEGDALKTEF 99
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
50-130 1.01e-03

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 38.44  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  50 DVPYVpTPKPVVDRMLE-LADVDETDVLyDLGSGDGRIvIRAARTHGARGVGIEIDPDLVKKARKNAKEA--GVADLVEF 126
Cdd:COG4976   25 DLGYE-APALLAEELLArLPPGPFGRVL-DLGCGTGLL-GEALRPRGYRLTGVDLSEEMLAKAREKGVYDrlLVADLADL 101


                 ....
gi 502826623 127 RQGD 130
Cdd:COG4976  102 AEPD 105
Methyltransf_15 pfam09445
RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as ...
 78-134 1.03e-03

RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as Schizosaccharomyces pombe Tgs1 and Giardia lamblia Tgs2 catalyze methylation of the exocyclic N2 amine of 7-methylguanosine.


Pssm-ID: 370496  Cd Length: 165  Bit Score: 38.08  E-value: 1.03e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 502826623   78 DLGSGDGRIVIRAARThGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEA 134
Cdd:pfam09445   6 DVFCGGGGNTIQFANV-FDSVISIDINLEHLACAQHNAEVYGVSDRIWLIHGDWFEL 61
hemK_fam TIGR00536
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme ...
 78-134 1.25e-03

HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme biosynthesis and originally suggested to be protoporphyrinogen oxidase. Functional analysis of the nearest homolog in Saccharomyces cerevisiae, YNL063w, finds it is not protoporphyrinogen oxidase and sequence analysis suggests that HemK homologs have S-adenosyl-methionine-dependent methyltransferase activity (Medline 99237242). Homologs are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both E. coli and H. influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain. [Protein fate, Protein modification and repair]


Pssm-ID: 273125 [Multi-domain]  Cd Length: 284  Bit Score: 38.87  E-value: 1.25e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 502826623   78 DLGSGDGRIVIRAARTHGARGV-GIEIDPDLVKKARKNAKEAGVADLVEFRQGDLFEA 134
Cdd:TIGR00536 120 DLGTGSGCIALALAYEFPNAEViAVDISPDALAVAEENAEKNQLEHRVEFIQSNLFEP 177
YhdJ COG0863
DNA modification methylase [Replication, recombination and repair];
55-113 1.45e-03

DNA modification methylase [Replication, recombination and repair];


Pssm-ID: 440623  Cd Length: 236  Bit Score: 38.37  E-value: 1.45e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502826623  55 PTPKPV--VDRMLELAdVDETDVLYD--LGSGDgriVIRAARTHGARGVGIEIDPDLVKKARK 113
Cdd:COG0863  164 PTQKPVelLERLILAS-SNPGDIVLDpfAGSGT---TLVAAERLGRRFIGIEIDPEYVEVARR 222
Trm5 COG2520
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ...
 63-130 1.81e-03

tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442010 [Multi-domain]  Cd Length: 333  Bit Score: 38.30  E-value: 1.81e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 502826623  63 RMLELADVDETdVLyDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVADLVEFRQGD 130
Cdd:COG2520  173 RIAELVKPGER-VL-DMFAGVGPFSIPIAKRSGAKVVAIDINPDAVEYLKENIRLNKVEDRVTPILGD 238
HsdM COG0286
Type I restriction-modification system, DNA methylase subunit [Defense mechanisms];
56-138 1.97e-03

Type I restriction-modification system, DNA methylase subunit [Defense mechanisms];


Pssm-ID: 440055 [Multi-domain]  Cd Length: 243  Bit Score: 37.86  E-value: 1.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502826623  56 TPKPVVDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARG---------VGIEIDPDLVKKARKNAKEAGVADlVEF 126
Cdd:COG0286   27 TPREVVRLMVELLDPKPGETVYDPACGSGGFLVEAAEYLKEHGgderkklslYGQEINPTTYRLAKMNLLLHGIGD-PNI 105

                         90
                 ....*....|..
gi 502826623 127 RQGDLFEADISE 138
Cdd:COG0286  106 ELGDTLSNDGDE 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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