NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|502969383|ref|WP_013204359|]
View 

MULTISPECIES: ABC transporter permease [Erwinia]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-306 5.27e-130

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 372.48  E-value: 5.27e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPARIYAGPDAPIEAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGVT 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  81 YRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVAMPFG 160
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 161 LFSVSGFNQPSD--------IILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVI 232
Cdd:COG0601  161 WLPVSGRVSPWEdfldalrhLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVV 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502969383 233 TMLGLQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAIRLR 306
Cdd:COG0601  241 TVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-306 5.27e-130

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 372.48  E-value: 5.27e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPARIYAGPDAPIEAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGVT 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  81 YRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVAMPFG 160
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 161 LFSVSGFNQPSD--------IILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVI 232
Cdd:COG0601  161 WLPVSGRVSPWEdfldalrhLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVV 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502969383 233 TMLGLQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAIRLR 306
Cdd:COG0601  241 TVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-306 4.73e-128

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 367.12  E-value: 4.73e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPARIYAGPDAPIEAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGVT 80
Cdd:PRK15081   1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  81 YRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVAMPFG 160
Cdd:PRK15081  81 MVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 161 LFSVSGFNQPSDIILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQFG 240
Cdd:PRK15081 161 WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFG 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502969383 241 FLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAIRLR 306
Cdd:PRK15081 241 FLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIRYK 306
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 113-304 2.20e-28

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 107.77  E-value: 2.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  113 GLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIqfvamPFGLFSVSGFNqpsdiILPAITLGSSVAAVMARFT 192
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLV-----VIAILSILGHG-----ILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  193 RSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQP 272
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|..
gi 502969383  273 VIQALVMLFVFEFIVINLLVDLLYAVVNPAIR 304
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 95-294 4.99e-19

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 83.10  E-value: 4.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  95 FMPTMWLALAGFAWSVLLGLIIGVISALKRGKWqDWTLMSLAVGGISMPPFWLGLLLIQFVAMPFGlfsvsgFNQPSDII 174
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG------WGILPGLG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 175 LPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQFGFLLGGSIVVESVFS 254
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 502969383 255 WPGLGWLLIESIKTQDQPVIQALVMLFVfefIVINLLVDL 294
Cdd:cd06261  154 GEAPGPGTGLLLIFAILFPGDLGVAAAV---ALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-306 5.27e-130

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 372.48  E-value: 5.27e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPARIYAGPDAPIEAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGVT 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  81 YRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVAMPFG 160
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 161 LFSVSGFNQPSD--------IILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVI 232
Cdd:COG0601  161 WLPVSGRVSPWEdfldalrhLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVV 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502969383 233 TMLGLQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAIRLR 306
Cdd:COG0601  241 TVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-306 4.73e-128

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 367.12  E-value: 4.73e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPARIYAGPDAPIEAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGVT 80
Cdd:PRK15081   1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  81 YRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVAMPFG 160
Cdd:PRK15081  81 MVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 161 LFSVSGFNQPSDIILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQFG 240
Cdd:PRK15081 161 WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFG 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502969383 241 FLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAIRLR 306
Cdd:PRK15081 241 FLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIRYK 306
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-304 3.18e-73

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 228.93  E-value: 3.18e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPARIYAGpDAPIEAVEAAR--QHLGLNDPLPQQYLHWLGGLVKGDLG 78
Cdd:PRK10914   1 MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAG-ERGISPERHAQllAELGLDKPMWQQYLHYIWGVMHGDLG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  79 VTYRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVAMP 158
Cdd:PRK10914  80 ISLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVH 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 159 FGLFSVSG------------------------FNQPSD-------IILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRT 207
Cdd:PRK10914 160 WNLTPVSGrvsdmvflddsnpltgfmlidtaiWGEDGNfidavahMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRT 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 208 ARAKGLRNRLVTWKHIMRNALIPVITMLGLQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIV 287
Cdd:PRK10914 240 ARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIIL 319

                        330
                 ....*....|....*..
gi 502969383 288 INLLVDLLYAVVNPAIR 304
Cdd:PRK10914 320 VNLLVDLLYGVVNPRIR 336
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-308 1.41e-70

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 221.11  E-value: 1.41e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPA----RIYAGPDAPiEAVEAARQHLGLNDPLPQQYLHWLGGLVKGD 76
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPAldylRLSNLPPTP-EMLASTRTMLGLDQPLYVQYGTWLWKALHLD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  77 LGVTYRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVA 156
Cdd:PRK10352  80 FGISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 157 MPFGLFSVSGFNQPSDIILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLG 236
Cdd:PRK10352 160 VYLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVG 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502969383 237 LQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAIRLRQE 308
Cdd:PRK10352 240 MHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEG 311
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-304 6.43e-58

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 188.35  E-value: 6.43e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPariYAGPDA-PIEAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGV 79
Cdd:PRK09471   1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSP---FTGERTlPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  80 TYRTQ-QPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVAMP 158
Cdd:PRK09471  78 SFKYKdYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAIT 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 159 FGLFSVSGFN--QPSDIILPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLG 236
Cdd:PRK09471 158 LHWLPGGGWNggALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMG 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 502969383 237 LQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAIR 304
Cdd:PRK09471 238 PAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
PRK15110 PRK15110
peptide ABC transporter permease SapB;
61-301 6.05e-42

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 147.53  E-value: 6.05e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  61 LPQQYLHWLGGLVKGDLGVTYRTQQPVTEVIAQGFMPTMWLALAGFAWSVLLGLIIGVISALKRGKWQDWTLMSLAVGGI 140
Cdd:PRK15110  40 LWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGF 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 141 SMPPFWLGLLLIQFVAMPFGLFSVSG-------------------------------FNQPSDIILPAITLGSSVAAVMA 189
Cdd:PRK15110 120 SIPVFWLALLLTLFFSLTLGWLPVSGrfdllyevkpvtgfalidawlsdspwrdemiMSAIRHMILPVITLAVAPTTEVI 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 190 RFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQ 269
Cdd:PRK15110 200 RLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQ 279

                        250       260       270
                 ....*....|....*....|....*....|..
gi 502969383 270 DQPVIQALVMLFVFEFIVINLLVDLLYAVVNP 301
Cdd:PRK15110 280 DYAAISAGVMVVGSLVIIVNVLSDILGAMANP 311
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 1-303 8.08e-33

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 124.14  E-value: 8.08e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDP----------------ARIYAGPDAPI------------------- 45
Cdd:COG4174    1 MGAYILRRLLLMIPTLLGIMLINFVIVQFAPGGPveqviaqlqgtgggatGRISGGGGDAGggaaagggskyrgargldp 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  46 EAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGVTYRTQQPVTEVIAQGfMP-TMWLALagfaWSVLLGLII----GVIS 120
Cdd:COG4174   81 EFIAELEKQYGFDKPAHERFLLMLKNYLRFDFGESYFRDISVIDLILEK-LPvSISLGL----WSTLLTYLIsiplGIRK 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 121 ALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVA-------MPF-GLFSvSGFNQPS----------DIILPAITLGS 182
Cdd:COG4174  156 AVRDGSRFDVWTSTVIIVGYAIPGFLFAILLIVLFAggsyfdwFPLrGLTS-DNWDQLSwwgkildylwHLTLPVTAMVI 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 183 SVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQF-GFLLGGSIVVESVFSWPGLGWL 261
Cdd:COG4174  235 GGFATLTLLTKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIAGFPAAFiGAFFTGSLLIETIFSLDGLGLL 314

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 502969383 262 LIESIKTQDQPVIQAlvMLFVFEFI--VINLLVDLLYAVVNPAI 303
Cdd:COG4174  315 GFEAVVNRDYPVVFG--TLYIFTLIglVLKLISDLTYVLVDPRI 356
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 113-304 2.20e-28

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 107.77  E-value: 2.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  113 GLIIGVISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIqfvamPFGLFSVSGFNqpsdiILPAITLGSSVAAVMARFT 192
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLV-----VIAILSILGHG-----ILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  193 RSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQFGFLLGGSIVVESVFSWPGLGWLLIESIKTQDQP 272
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|..
gi 502969383  273 VIQALVMLFVFEFIVINLLVDLLYAVVNPAIR 304
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 1-303 3.38e-21

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 92.50  E-value: 3.38e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383   1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDP-----ARIYAGPDAPI------------------------------ 45
Cdd:PRK15133   1 MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPvdqaiAAIEFGQAGGLpgaggegvrashaqtgvgnisdsnyrggrg 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  46 ---EAVEAARQHLGLNDPLPQQYLHWLGGLVKGDLGVTYRTQQPVTEVIAQGFMPTMWLALagfaWSVLLGLII----GV 118
Cdd:PRK15133  81 ldpEVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGL----WSTLIIYLVsiplGI 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 119 ISALKRGKWQDWTLMSLAVGGISMPPFWLGLLLIQFVA--MPFGLFSVSGFNQPS---------------DIILPAITLG 181
Cdd:PRK15133 157 RKAVRNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAggSYFDLFPLRGLVSANfdslpwyqkitdylwHITLPVLATV 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 182 SSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQF-GFLLGGSIVVESVFSWPGLGW 260
Cdd:PRK15133 237 IGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFiSMFFTGSLLIEVMFSLNGLGL 316

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 502969383 261 LLIESIKTQDQPVIQALVMLFVFEFIVINLLVDLLYAVVNPAI 303
Cdd:PRK15133 317 LGYEATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 95-294 4.99e-19

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 83.10  E-value: 4.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  95 FMPTMWLALAGFAWSVLLGLIIGVISALKRGKWqDWTLMSLAVGGISMPPFWLGLLLIQFVAMPFGlfsvsgFNQPSDII 174
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG------WGILPGLG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 175 LPAITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLGLQFGFLLGGSIVVESVFS 254
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 502969383 255 WPGLGWLLIESIKTQDQPVIQALVMLFVfefIVINLLVDL 294
Cdd:cd06261  154 GEAPGPGTGLLLIFAILFPGDLGVAAAV---ALILLLLSL 190
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-102 1.16e-15

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 71.87  E-value: 1.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383    1 MFAYLVRRLLEMIPVLLVVSLLVFAFIKLLPGDPARIYAGPDAPIEAVEAARQHLGLNDPLPQQYLHWLGGLVKGD---- 76
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDPARLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRdfga 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 502969383   77 --------LGVTYRTQQPVTEVIAQGFMPTMWLA 102
Cdd:pfam19300  81 vghcpapcLGYSFANNEPVWDTIMDRFPTTLSLA 114
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 98-259 3.10e-14

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 3.10e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383  98 TMWLALAGFAWSVLLGLIIGVISALKRGKWqDWTLMSLAVGGISMPPFWLGLLLIqfVAMPFGLFSVsgfnqpsdiilpA 177
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAGYFGGWV-DAVLMRLVDVLLAFPSLLLAIALV--AVLGPGLLNV------------I 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 178 ITLGSSVAAVMARFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITmlglQFGFLLGGSIVVESVFSWPG 257
Cdd:COG1173  146 LALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIV----QATLGIASAILAEAGLSFLG 221


                 ..
gi 502969383 258 LG 259
Cdd:COG1173  222 LG 223
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 105-248 3.49e-08

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 54.00  E-value: 3.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 105 GFAWSVLLGLIIGVISalkrgkwqdwTLMSLAVGGIsMPPF--WLGLLLIQFV----AMP--FGLFSVSGFNQPSDIILP 176
Cdd:COG4239  139 GFRISVLFGLALTVIS----------SVIGVAAGAV-QGYFggRVDLLFQRFIeiwsSMPelYLLIILSSIFQPSFWLLL 207

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 502969383 177 AITLGSS---VAAVMarftRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLglqfGFLLGGSIV 248
Cdd:COG4239  208 GILLLFGwmgLVGVV----RAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTFL----PFILSGAIT 274
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 109-259 1.26e-04

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 43.05  E-value: 1.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502969383 109 SVLLGLIIGVISALKRGKWQDWTLMSLAVGGiSMPPFWLGLLLIQFVampfglfsvsgfnQPSDIILPAITLGSSVAAVM 188
Cdd:PRK15021 154 SSVMGVLAGALQGYYGGKVDLWGQRFIEVWS-GMPTLFLIILLSSVV-------------QPNFWWLLAITVLFGWMSLV 219

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 502969383 189 ArFTRSAFLEVAQEDYVRTARAKGLRNRLVTWKHIMRNALIPVITMLglqfGFLLGGSIVVESVFSWPGLG 259
Cdd:PRK15021 220 G-VVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFL----PFILCSSITTLTSLDFLGFG 285
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH