|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1045 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1510.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 1 MLEKIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQ 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 81 YTRSISRYGLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTGLGEIFMYTVEAKPDArkadgtaYTP 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGK-------YSL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 161 EDLRTLQDWVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRV 240
Cdd:COG3696 154 MELRTLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 241 PGQANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGK-EVVVATVNMLIGENSRTVAKAVSEKLAAANKS 319
Cdd:COG3696 234 IGLIRSLEDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAELKPS 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 320 LPEGVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLG 399
Cdd:COG3696 314 LPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 400 --ALDFGLIVDGAVIIMENCLRRFAEAQHHHgrllTRDERFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMF 477
Cdd:COG3696 394 glAIDFGIIVDGAVVMVENILRRLEENRAAG----TPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLF 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 478 HPMAATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESFVMRGARKVYEPILKLAIKARYALVGIAIVLVVLSGFLATR 557
Cdd:COG3696 470 RPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPR 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 558 LGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVATDPMPPSVADTFVILKDRKKW 637
Cdd:COG3696 550 LGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEW 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 638 PNPnEPKNSLVERMQKAVEEIPGNNYEFTQPIQMRFNELISGVRSDVAVKIFGDDLDQLLKTGNDIQKVMKTIPGAEDVR 717
Cdd:COG3696 630 RSG-RTKEELIAEMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQ 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 718 VEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLRIPVSNdg 797
Cdd:COG3696 709 VERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPS-- 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 798 dsaegmtGAsFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVRGADLGTFVTTLQDKVGAQVKLPEGYWVNYGGTFEQ 877
Cdd:COG3696 787 -------GA-QVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFEN 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 878 MTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIALSGVAVLNGVVM 957
Cdd:COG3696 859 LQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVL 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 958 LTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLILPALY 1037
Cdd:COG3696 939 VSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALY 1018
|
....*...
gi 503246615 1038 RIVHGKEK 1045
Cdd:COG3696 1019 LLFGRRRL 1026
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1049 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1419.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 1 MLEKIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQ 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 81 YTRSISRYGLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTGLGEIFMYTVEAKPDARKADGTAYTP 160
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGARKKDGGAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 161 EDLRTLQDWVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRV 240
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 241 PGQANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSL 320
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 321 PEGVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGA 400
Cdd:TIGR00914 321 PEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 401 LDFGLIVDGAVIIMENCLRRFAEAQHHHGRLLTRDERFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMFHPM 480
Cdd:TIGR00914 401 LDFGLIVDGAVVIVENAHRRLAEAQHHHGRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPM 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 481 AATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESFVMRGARKVYEPILKLAIKARYALVGIAIVLVVLSGFLATRLGA 560
Cdd:TIGR00914 481 AFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 561 EFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVATDPMPPSVADTFVILKDRKKWPNP 640
Cdd:TIGR00914 561 EFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQWPEG 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 641 NEPKNSLVERMQKAVEEIPGNNYEFTQPIQMRFNELISGVRSDVAVKIFGDDLDQLLKTGNDIQKVMKTIPGAEDVRVEQ 720
Cdd:TIGR00914 641 KKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVEQ 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 721 VSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLRIPVSNDGDSA 800
Cdd:TIGR00914 721 TTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDAR 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 801 EgmtgaSFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVRGADLGTFVTTLQDKVGAQVKLPEGYWVNYGGTFEQMTS 880
Cdd:TIGR00914 801 K-----QFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQS 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 881 AAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIALSGVAVLNGVVMLTF 960
Cdd:TIGR00914 876 ATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 961 IKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLILPALYRIV 1040
Cdd:TIGR00914 956 IRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLV 1035
|
....*....
gi 503246615 1041 HGKEKTLEK 1049
Cdd:TIGR00914 1036 HRRRHKGRK 1044
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1041 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1028.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 5 IIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 85 ISRYGLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQ-LGPISTGLGEIFMYTVEAkpdarkaDGTAYTPEDL 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPgISVIKTSLGPIMVLAVTS-------PDGSYTQTDL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 164 RTLQDWVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRVPGQ 243
Cdd:pfam00873 154 RDYADTNIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 244 ANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPEG 323
Cdd:pfam00873 234 LQSAEDFEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 324 VSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGALDF 403
Cdd:pfam00873 314 VEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVL 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 404 --GLIVDGAVIIMENCLRRFAEAQHHHgrlltrderFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMFHPMA 481
Cdd:pfam00873 394 aiGLVVDDAIVVVENIERVLEENGLKP---------LEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 482 ATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKES-------FVMRGARKVYEPILKLAIKARYALVGIAIVLVVLSGFL 554
Cdd:pfam00873 465 ITIVLAILLSVLVALTLTPALCATLLKPRREPKHGgffrwfnRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWL 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 555 ATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEvATDPMPPSVADTFVILKDR 634
Cdd:pfam00873 545 FVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKPW 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 635 KKWPNPNEPKNSLVERMQKAVEEIPGNNYEFTQPIQMRFNELISGVRSDVAVKIFGDDLDQLLKTGNDIQKVMKTIPGAE 714
Cdd:pfam00873 624 KERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLS 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 715 DVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLRIPVS 794
Cdd:pfam00873 704 DVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNP 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 795 NDGdsaegmtgasFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVRGADLGTFVTTLQDKVGAQVKLPEGYWVNYGGT 874
Cdd:pfam00873 784 YGK----------MIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQ 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 875 FEQMTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIALSGVAVLNG 954
Cdd:pfam00873 854 FEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNA 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 955 VVMLTFIKSLRA-EGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLIL 1033
Cdd:pfam00873 934 ILMVEFANELREqEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVV 1013
|
....*...
gi 503246615 1034 PALYRIVH 1041
Cdd:pfam00873 1014 PVFYVLFH 1021
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
9-1040 |
1.92e-126 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 410.56 E-value: 1.92e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 9 SIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRY 88
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 89 GLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTG-LGEIFMYTveakpdarkadGTAYTPEDLRTLQ 167
Cdd:NF033617 84 GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANsADTPIMYI-----------GLTSEEMPRGQLT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 168 DW---VIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRVPGQA 244
Cdd:NF033617 153 DYaerVLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 245 NTIEDLKQIVVQTRM-GVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPEG 323
Cdd:NF033617 233 KTAEDYEDLVIKYADnGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 324 VSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGA--L 401
Cdd:NF033617 313 IKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMAlvL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 402 DFGLIVDGAVIIMENCLRRFAEAqhhhgrlltrDERFALASKASTEVikpsLFGVLIITI----VYFPIFALSGVEGKMF 477
Cdd:NF033617 393 AIGLVVDDAIVVVENIHRHIEEG----------ESPLEAALKGAREI----GFTVIAMTLtlvaVYLPILFMGGLTGRLF 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 478 HPMAATVVMALAAALVLSLTFVPAAVAMFVtgKVQEKESFVMRGARKV-------YEPILKLAIKARYALVGIAIVLVVL 550
Cdd:NF033617 459 REFAVTLAGAVIISGIVALTLTPMMCSRLL--KANEKPGRFARAVDRFfdgltarYGRGLKWVLKHRPLTLVVALATLAL 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 551 SGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVATDpmppSVADTFVI 630
Cdd:NF033617 537 LPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGD----NTGFGIIN 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 631 LKDrkkWPNPNEPKNSLVERMQKAVEEIPGNNYeFTQPIQmrfnELISGVRSDVAVKIF---GDDLDQLLKTGNDIQKVM 707
Cdd:NF033617 613 LKP---WDERDVSAQEIIDRLRPKLAKVPGMDL-FLFPLQ----DLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKL 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 708 KTIPGAEDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIG 787
Cdd:NF033617 685 RKSPQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALN 764
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 788 RLRIPvSNDGDSaegmtgasfIPLQDVAHIEMINGPNQISREQGKRRVVVTANV-RGADLGTFVTTLQDKvgAQVKLPEG 866
Cdd:NF033617 765 QIYVR-SNDGKL---------VPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLaPGVSLGEAIEALDQA--AKELLPSG 832
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 867 YWVNYGGTFEQMTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIAL 946
Cdd:NF033617 833 ISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITL 912
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 947 SGVAVLNGVVMLTFIKSLRAEGKL-LDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSS 1025
Cdd:NF033617 913 IGLVKKNGILMVEFANELQRHQGLsRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVG 992
|
1050
....*....|....*
gi 503246615 1026 TILTLLILPALYRIV 1040
Cdd:NF033617 993 TLFTLFVLPVVYLLL 1007
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
15-1040 |
6.80e-70 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 253.62 E-value: 6.80e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 15 IVMIVVLAlsalGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRYGLSQVT 94
Cdd:PRK09577 15 ISLFIMLG----GIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 95 VVFKEGTDIYFARQLVNERVQSVRSQLPagsEP-QLGPIStglgeifmytVEAKPDARK------ADGTAYTPEDLRTLQ 167
Cdd:PRK09577 91 LTFKQGVNADLAAVEVQNRLKTVEARLP---EPvRRDGIQ----------VEKAADNIQlivsltSDDGRLTGVELGEYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 168 DWVIRPQLRNTPGVTEVNTIGGfERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGeqflvrVPGQA--- 244
Cdd:PRK09577 158 SANVLQALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSA------VPDSApia 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 245 ---------NTIEDLKQIVVQTRM-GVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLA 314
Cdd:PRK09577 231 atvfadaplKTPEDFGAIALRARAdGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMD 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 315 AANKSLPEGVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGN 394
Cdd:PRK09577 311 ELSRYFPPGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSIN 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 395 LMSL--GALDFGLIVDGAVIIMENCLRRFAEAqhhhgRLLTRDerfalASKASTEVIKPSLFGV-LIITIVYFPIFALSG 471
Cdd:PRK09577 391 VLTMfgMVLAIGILVDDAIVVVENVERLMVEE-----GLSPYD-----ATVKAMKQISGAIVGItVVLTSVFVPMAFFGG 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 472 VEGKMFHPMAATVVMALAAALVLSLTFVPAAVAMF---VTGKVQEKESF-----------VMRGARKVyEPILKLAIkaR 537
Cdd:PRK09577 461 AVGNIYRQFALSLAVSIGFSAFLALSLTPALCATLlkpVDGDHHEKRGFfgwfnrfvarsTQRYATRV-GAILKRPL--R 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 538 YALVGIAIVLVVlsGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVAT 617
Cdd:PRK09577 538 WLVVYGALTAAA--ALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGE 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 618 DpmpPSVADTFVILKDRKKWPNPNEPKNSLVERMQK-----------AVEEIPGNNYEFTQPIQMRFNElisgvRSDVAV 686
Cdd:PRK09577 616 G---PNGGMIFVTLKDWKERKAARDHVQAIVARINErfagtpnttvfAMNSPALPDLGSTSGFDFRLQD-----RGGLGY 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 687 KIFGDDLDQLLKTGndiqkvMKTiPGAEDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGD 766
Cdd:PRK09577 688 AAFVAAREQLLAEG------AKD-PALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGS 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 767 RRFNVIVRLPETQRANLAEIGRLRIpvsndgDSAEGmtgaSFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVR-GAD 845
Cdd:PRK09577 761 QVRRVIVQADGRHRLDPDDVKKLRV------RNAQG----EMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAApGHS 830
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 846 LGTFVTTLQDKVGaqvKLPEGYWVNYGG-TFEQMTSAAKrlqivVPIALILIIGLLFMLFGTM-EDALIVFS---GVPLA 920
Cdd:PRK09577 831 SGEAMAAIERIAA---TLPAGIGYAWSGqSFEERLSGAQ-----APMLFALSVLVVFLALAALyESWSIPFAvmlVVPLG 902
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 921 LTGGIVALAIRDIPLSISAGVGFIALSGVAVLNGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPM 1000
Cdd:PRK09577 903 VIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPL 982
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|
gi 503246615 1001 AFNVGAGSEVQRPLATVVIGGIVSSTILTLLILPALYRIV 1040
Cdd:PRK09577 983 AFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
3-271 |
1.28e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 43.08 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 3 EKIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYT 82
Cdd:NF033617 513 GRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSL 592
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 83 RSISRYGLSQ------VTVVFKEGTDIYFARQLVNERVQSVRSQLPaGSEP-----QLGPISTGLG-EIFMYTVeakpda 150
Cdd:NF033617 593 TSFNGVGGNPgdntgfGIINLKPWDERDVSAQEIIDRLRPKLAKVP-GMDLflfplQDLPGGAGSSlPQYQVTL------ 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 151 rkadgtayTPEDLRTLQDWV--IRPQLRNTPGVTEVNTIGGFER-QYHVTPFPERLSAYSLTMADVIKALETNNSNRGAG 227
Cdd:NF033617 666 --------TPSDYDSLFTWAekLKEKLRKSPQFADVDSDLQDKGpELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVN 737
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 503246615 228 YVEKSGEQFLV--RV-PGQANTIEDLKQIVVQTRMGVPIRIADVADV 271
Cdd:NF033617 738 TIYTDGNQYKVvlEVdRRYRLNPEALNQIYVRSNDGKLVPLSTLAKI 784
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1045 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1510.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 1 MLEKIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQ 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 81 YTRSISRYGLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTGLGEIFMYTVEAKPDArkadgtaYTP 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGK-------YSL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 161 EDLRTLQDWVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRV 240
Cdd:COG3696 154 MELRTLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 241 PGQANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGK-EVVVATVNMLIGENSRTVAKAVSEKLAAANKS 319
Cdd:COG3696 234 IGLIRSLEDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAELKPS 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 320 LPEGVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLG 399
Cdd:COG3696 314 LPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 400 --ALDFGLIVDGAVIIMENCLRRFAEAQHHHgrllTRDERFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMF 477
Cdd:COG3696 394 glAIDFGIIVDGAVVMVENILRRLEENRAAG----TPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLF 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 478 HPMAATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESFVMRGARKVYEPILKLAIKARYALVGIAIVLVVLSGFLATR 557
Cdd:COG3696 470 RPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPR 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 558 LGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVATDPMPPSVADTFVILKDRKKW 637
Cdd:COG3696 550 LGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEW 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 638 PNPnEPKNSLVERMQKAVEEIPGNNYEFTQPIQMRFNELISGVRSDVAVKIFGDDLDQLLKTGNDIQKVMKTIPGAEDVR 717
Cdd:COG3696 630 RSG-RTKEELIAEMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQ 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 718 VEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLRIPVSNdg 797
Cdd:COG3696 709 VERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPS-- 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 798 dsaegmtGAsFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVRGADLGTFVTTLQDKVGAQVKLPEGYWVNYGGTFEQ 877
Cdd:COG3696 787 -------GA-QVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFEN 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 878 MTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIALSGVAVLNGVVM 957
Cdd:COG3696 859 LQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVL 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 958 LTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLILPALY 1037
Cdd:COG3696 939 VSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALY 1018
|
....*...
gi 503246615 1038 RIVHGKEK 1045
Cdd:COG3696 1019 LLFGRRRL 1026
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1049 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1419.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 1 MLEKIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQ 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 81 YTRSISRYGLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTGLGEIFMYTVEAKPDARKADGTAYTP 160
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGARKKDGGAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 161 EDLRTLQDWVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRV 240
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 241 PGQANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSL 320
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 321 PEGVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGA 400
Cdd:TIGR00914 321 PEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 401 LDFGLIVDGAVIIMENCLRRFAEAQHHHGRLLTRDERFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMFHPM 480
Cdd:TIGR00914 401 LDFGLIVDGAVVIVENAHRRLAEAQHHHGRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPM 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 481 AATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESFVMRGARKVYEPILKLAIKARYALVGIAIVLVVLSGFLATRLGA 560
Cdd:TIGR00914 481 AFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 561 EFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVATDPMPPSVADTFVILKDRKKWPNP 640
Cdd:TIGR00914 561 EFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQWPEG 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 641 NEPKNSLVERMQKAVEEIPGNNYEFTQPIQMRFNELISGVRSDVAVKIFGDDLDQLLKTGNDIQKVMKTIPGAEDVRVEQ 720
Cdd:TIGR00914 641 KKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVEQ 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 721 VSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLRIPVSNDGDSA 800
Cdd:TIGR00914 721 TTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDAR 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 801 EgmtgaSFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVRGADLGTFVTTLQDKVGAQVKLPEGYWVNYGGTFEQMTS 880
Cdd:TIGR00914 801 K-----QFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQS 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 881 AAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIALSGVAVLNGVVMLTF 960
Cdd:TIGR00914 876 ATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 961 IKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLILPALYRIV 1040
Cdd:TIGR00914 956 IRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLV 1035
|
....*....
gi 503246615 1041 HGKEKTLEK 1049
Cdd:TIGR00914 1036 HRRRHKGRK 1044
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1041 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1028.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 5 IIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 85 ISRYGLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQ-LGPISTGLGEIFMYTVEAkpdarkaDGTAYTPEDL 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPgISVIKTSLGPIMVLAVTS-------PDGSYTQTDL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 164 RTLQDWVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRVPGQ 243
Cdd:pfam00873 154 RDYADTNIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 244 ANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPEG 323
Cdd:pfam00873 234 LQSAEDFEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 324 VSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGALDF 403
Cdd:pfam00873 314 VEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVL 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 404 --GLIVDGAVIIMENCLRRFAEAQHHHgrlltrderFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMFHPMA 481
Cdd:pfam00873 394 aiGLVVDDAIVVVENIERVLEENGLKP---------LEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 482 ATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKES-------FVMRGARKVYEPILKLAIKARYALVGIAIVLVVLSGFL 554
Cdd:pfam00873 465 ITIVLAILLSVLVALTLTPALCATLLKPRREPKHGgffrwfnRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWL 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 555 ATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEvATDPMPPSVADTFVILKDR 634
Cdd:pfam00873 545 FVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKPW 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 635 KKWPNPNEPKNSLVERMQKAVEEIPGNNYEFTQPIQMRFNELISGVRSDVAVKIFGDDLDQLLKTGNDIQKVMKTIPGAE 714
Cdd:pfam00873 624 KERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLS 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 715 DVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLRIPVS 794
Cdd:pfam00873 704 DVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNP 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 795 NDGdsaegmtgasFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVRGADLGTFVTTLQDKVGAQVKLPEGYWVNYGGT 874
Cdd:pfam00873 784 YGK----------MIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQ 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 875 FEQMTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIALSGVAVLNG 954
Cdd:pfam00873 854 FEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNA 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 955 VVMLTFIKSLRA-EGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLIL 1033
Cdd:pfam00873 934 ILMVEFANELREqEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVV 1013
|
....*...
gi 503246615 1034 PALYRIVH 1041
Cdd:pfam00873 1014 PVFYVLFH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
4-1047 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 692.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 4 KIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTR 83
Cdd:COG0841 2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 84 SISRYGLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAG-SEPQLGPISTGLGEIFMYTVEakpdarkadGTAYTPED 162
Cdd:COG0841 82 STSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDvEPPGVTKVNPSDFPVMVLALS---------SDDLDELE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 163 LRTLQDWVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRVPG 242
Cdd:COG0841 153 LSDYAERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 243 QANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPE 322
Cdd:COG0841 233 RLKTPEEFENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 323 GVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMvenKVSG---NLMSLG 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVM---YLLGfslNILTLF 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 400 ALDF--GLIVDGAVIIMENCLRRFAEAQhhhgrlltrdERFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMF 477
Cdd:COG0841 390 ALVLaiGIVVDDAIVVVENIERHMEEGL----------SPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLF 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 478 HPMAATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESFVMRGA-------RKVYEPILKLAIKARYALVGIAIVLVVL 550
Cdd:COG0841 460 RQFALTVAIALLISLFVALTLTPALCARLLKPHPKGKKGRFFRAFnrgfdrlTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 551 SGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVATDpmpPSVADTFVI 630
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSG---SNSGTIFVT 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 631 LKDrkkWPNPNEPKNSLVERMQKAVEEIPGNNYEFTQPIQMRFnelisGVRSDVAVKIFGDDLDQLLKTGNDIQKVMKTI 710
Cdd:COG0841 617 LKP---WDERDRSADEIIARLREKLAKIPGARVFVFQPPAGGL-----GSGAPIEVQLQGDDLEELAAAAEKLLAALRQI 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 711 PGAEDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLR 790
Cdd:COG0841 689 PGLVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLY 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 791 IPvSNDGDSaegmtgasfIPLQDVAHIEMINGPNQISREQGKRRVVVTANV-RGADLGTFVTTLQDKVgAQVKLPEGYWV 869
Cdd:COG0841 769 VR-TPDGEM---------VPLSSVATIEEGTGPSSINRYNGQRSVTVSANLaPGVSLGEALAAIEELA-AELKLPPGVSI 837
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 870 NYGGTFEQMTSAAKRLQ-------IVVpialiliigllFM----LFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSIS 938
Cdd:COG0841 838 EFTGQAEEEQESFSSLGlafllalLLV-----------YLvlaaQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIY 906
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 939 AGVGFIALSGVAVLNGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVV 1018
Cdd:COG0841 907 SQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAV 986
|
1050 1060
....*....|....*....|....*....
gi 503246615 1019 IGGIVSSTILTLLILPALYRIVHGKEKTL 1047
Cdd:COG0841 987 IGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
9-1040 |
1.92e-126 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 410.56 E-value: 1.92e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 9 SIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRY 88
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 89 GLSQVTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTG-LGEIFMYTveakpdarkadGTAYTPEDLRTLQ 167
Cdd:NF033617 84 GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANsADTPIMYI-----------GLTSEEMPRGQLT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 168 DW---VIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRVPGQA 244
Cdd:NF033617 153 DYaerVLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 245 NTIEDLKQIVVQTRM-GVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPEG 323
Cdd:NF033617 233 KTAEDYEDLVIKYADnGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 324 VSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGA--L 401
Cdd:NF033617 313 IKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMAlvL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 402 DFGLIVDGAVIIMENCLRRFAEAqhhhgrlltrDERFALASKASTEVikpsLFGVLIITI----VYFPIFALSGVEGKMF 477
Cdd:NF033617 393 AIGLVVDDAIVVVENIHRHIEEG----------ESPLEAALKGAREI----GFTVIAMTLtlvaVYLPILFMGGLTGRLF 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 478 HPMAATVVMALAAALVLSLTFVPAAVAMFVtgKVQEKESFVMRGARKV-------YEPILKLAIKARYALVGIAIVLVVL 550
Cdd:NF033617 459 REFAVTLAGAVIISGIVALTLTPMMCSRLL--KANEKPGRFARAVDRFfdgltarYGRGLKWVLKHRPLTLVVALATLAL 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 551 SGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVATDpmppSVADTFVI 630
Cdd:NF033617 537 LPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGD----NTGFGIIN 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 631 LKDrkkWPNPNEPKNSLVERMQKAVEEIPGNNYeFTQPIQmrfnELISGVRSDVAVKIF---GDDLDQLLKTGNDIQKVM 707
Cdd:NF033617 613 LKP---WDERDVSAQEIIDRLRPKLAKVPGMDL-FLFPLQ----DLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKL 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 708 KTIPGAEDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIG 787
Cdd:NF033617 685 RKSPQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALN 764
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 788 RLRIPvSNDGDSaegmtgasfIPLQDVAHIEMINGPNQISREQGKRRVVVTANV-RGADLGTFVTTLQDKvgAQVKLPEG 866
Cdd:NF033617 765 QIYVR-SNDGKL---------VPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLaPGVSLGEAIEALDQA--AKELLPSG 832
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 867 YWVNYGGTFEQMTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIAL 946
Cdd:NF033617 833 ISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITL 912
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 947 SGVAVLNGVVMLTFIKSLRAEGKL-LDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSS 1025
Cdd:NF033617 913 IGLVKKNGILMVEFANELQRHQGLsRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVG 992
|
1050
....*....|....*
gi 503246615 1026 TILTLLILPALYRIV 1040
Cdd:NF033617 993 TLFTLFVLPVVYLLL 1007
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
14-1057 |
1.76e-88 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 307.43 E-value: 1.76e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 14 WIVMIVVLALSALGVYnftRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRY-GLSQ 92
Cdd:TIGR00915 13 WVIAIIIMLAGTLSIL---SLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSDSdGSMT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 93 VTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTGLGEIFMYTVEAKPDArkadgtAYTPEDLRTLQDWVIR 172
Cdd:TIGR00915 90 ITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDG------SMTKEDLSDYAASNMV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 173 PQLRNTPGVTEVNTIGGferQYHVTPF--PERLSAYSLTMADVIKALETNNSNRGAGYV----EKSGEQFLVRVPGQA-- 244
Cdd:TIGR00915 164 DPLSRLEGVGDVQLFGS---QYAMRIWldPAKLNSYQLTPADVISAISAQNAQISAGQLgglpAVPGQQLNATIIAQTrl 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 245 NTIEDLKQIVVQTRM-GVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPEG 323
Cdd:TIGR00915 241 QTPEQFENILLKVNTdGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 324 VSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGA--L 401
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAmvL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 402 DFGLIVDGAVIIMENCLRRFAEAQhhhgrlLTRDErfalASKASTEVIKPSLFGV-LIITIVYFPIFALSGVEGKMFHPM 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEG------LPPKE----ATRKSMGQIQGALVGIaMVLSAVFVPMAFFGGSTGAIYRQF 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 481 AATVVMALAAALVLSLTFVPAAVA-MFVTGKVQEKESFVM-----------RGARKvYEPILKLAIKARYALVGIAIVLV 548
Cdd:TIGR00915 471 SITIVSAMALSVLVALILTPALCAtMLKPIEKGEHHEKKGgffgwfnrmfdSSTHG-YENGVGKILRRRGRYLLVYVLLV 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 549 VLSGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARL--KKFPEVERVFAKIGTAEVATDPmppSVAD 626
Cdd:TIGR00915 550 GGMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLlaKEKANVESVFTVNGFSFAGRGQ---NMGM 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 627 TFVILKDRKKWPNPNEPKNSLVERMQKAVEEIP-GNNYEFTQPIqmrfnelISGVRSDVAVKIF-----GDDLDQLLKTG 700
Cdd:TIGR00915 627 AFIRLKDWEERTGKENSVFAIAGRATGHFMQIKdAMVIAFVPPA-------ILELGNATGFDFFlqdraGLGHEALLQAR 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 701 NDIQKVMKTIPGAEDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQR 780
Cdd:TIGR00915 700 NQLLGLAAQNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDAR 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 781 ANLAEIGRLRIPvSNDGDsaegmtgasFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVR-GADLGTFVTTLQDKVGa 859
Cdd:TIGR00915 780 MSPEDINKWYVR-NASGE---------MVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAApGVSTGQAMAAMEAIAQ- 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 860 qvKLPEGYWVNYGG-TFEQMTSAAKrlqivVPIALILIIGLLFM----LFGTMEDALIVFSGVPLALTGGIVALAIRDIP 934
Cdd:TIGR00915 849 --KLPPGFGFSWTGmSYEERLSGSQ-----APALYALSLLVVFLclaaLYESWSIPVSVMLVVPLGIIGALLATTLRGLS 921
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 935 LSISAGVGFIALSGVAVLNGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPL 1014
Cdd:TIGR00915 922 NDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAI 1001
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|...
gi 503246615 1015 ATVVIGGIVSSTILTLLILPALYRIVHGKEKTLEKNRPAPNRE 1057
Cdd:TIGR00915 1002 GTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEKEMSVEH 1044
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
15-1040 |
6.80e-70 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 253.62 E-value: 6.80e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 15 IVMIVVLAlsalGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRYGLSQVT 94
Cdd:PRK09577 15 ISLFIMLG----GIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 95 VVFKEGTDIYFARQLVNERVQSVRSQLPagsEP-QLGPIStglgeifmytVEAKPDARK------ADGTAYTPEDLRTLQ 167
Cdd:PRK09577 91 LTFKQGVNADLAAVEVQNRLKTVEARLP---EPvRRDGIQ----------VEKAADNIQlivsltSDDGRLTGVELGEYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 168 DWVIRPQLRNTPGVTEVNTIGGfERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGeqflvrVPGQA--- 244
Cdd:PRK09577 158 SANVLQALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSA------VPDSApia 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 245 ---------NTIEDLKQIVVQTRM-GVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLA 314
Cdd:PRK09577 231 atvfadaplKTPEDFGAIALRARAdGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMD 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 315 AANKSLPEGVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGN 394
Cdd:PRK09577 311 ELSRYFPPGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSIN 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 395 LMSL--GALDFGLIVDGAVIIMENCLRRFAEAqhhhgRLLTRDerfalASKASTEVIKPSLFGV-LIITIVYFPIFALSG 471
Cdd:PRK09577 391 VLTMfgMVLAIGILVDDAIVVVENVERLMVEE-----GLSPYD-----ATVKAMKQISGAIVGItVVLTSVFVPMAFFGG 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 472 VEGKMFHPMAATVVMALAAALVLSLTFVPAAVAMF---VTGKVQEKESF-----------VMRGARKVyEPILKLAIkaR 537
Cdd:PRK09577 461 AVGNIYRQFALSLAVSIGFSAFLALSLTPALCATLlkpVDGDHHEKRGFfgwfnrfvarsTQRYATRV-GAILKRPL--R 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 538 YALVGIAIVLVVlsGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVAT 617
Cdd:PRK09577 538 WLVVYGALTAAA--ALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGE 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 618 DpmpPSVADTFVILKDRKKWPNPNEPKNSLVERMQK-----------AVEEIPGNNYEFTQPIQMRFNElisgvRSDVAV 686
Cdd:PRK09577 616 G---PNGGMIFVTLKDWKERKAARDHVQAIVARINErfagtpnttvfAMNSPALPDLGSTSGFDFRLQD-----RGGLGY 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 687 KIFGDDLDQLLKTGndiqkvMKTiPGAEDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGD 766
Cdd:PRK09577 688 AAFVAAREQLLAEG------AKD-PALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGS 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 767 RRFNVIVRLPETQRANLAEIGRLRIpvsndgDSAEGmtgaSFIPLQDVAHIEMINGPNQISREQGKRRVVVTANVR-GAD 845
Cdd:PRK09577 761 QVRRVIVQADGRHRLDPDDVKKLRV------RNAQG----EMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAApGHS 830
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 846 LGTFVTTLQDKVGaqvKLPEGYWVNYGG-TFEQMTSAAKrlqivVPIALILIIGLLFMLFGTM-EDALIVFS---GVPLA 920
Cdd:PRK09577 831 SGEAMAAIERIAA---TLPAGIGYAWSGqSFEERLSGAQ-----APMLFALSVLVVFLALAALyESWSIPFAvmlVVPLG 902
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 921 LTGGIVALAIRDIPLSISAGVGFIALSGVAVLNGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPM 1000
Cdd:PRK09577 903 VIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPL 982
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|
gi 503246615 1001 AFNVGAGSEVQRPLATVVIGGIVSSTILTLLILPALYRIV 1040
Cdd:PRK09577 983 AFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
14-1040 |
8.50e-63 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 232.41 E-value: 8.50e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 14 WIVMIVvlaLSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRY-GLSQ 92
Cdd:PRK10555 13 WVLAIL---LCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGtGQAS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 93 VTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPIS-TGLGEIFMYTVEAkpdarkADGTAytpeDLRTLQDWV- 170
Cdd:PRK10555 90 VTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRkTGDTNILTIAFVS------TDGSM----DKQDIADYVa 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 171 --IRPQLRNTPGVTEVNTIGGferQYHVTPF--PERLSAYSLTMADVIKALETNNSNRGAGY------VEKSGEQFLVRV 240
Cdd:PRK10555 160 snIQDPLSRVNGVGDIDAYGS---QYSMRIWldPAKLNSFQMTTKDVTDAIESQNAQIAVGQlggtpsVDKQALNATINA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 241 PGQANTIEDLKQIVVQTRM-GVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKS 319
Cdd:PRK10555 237 QSLLQTPEQFRDITLRVNQdGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 320 LPEGVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLG 399
Cdd:PRK10555 317 FPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMF 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 400 A--LDFGLIVDGAVIIMENCLRRFAEAQhhhgrLLTRDerfalASKASTEVIKPSLFGV-LIITIVYFPIFALSGVEGKM 476
Cdd:PRK10555 397 AmvLAIGLLVDDAIVVVENVERIMSEEG-----LTPRE-----ATRKSMGQIQGALVGIaMVLSAVFVPMAFFGGTTGAI 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 477 FHPMAATVVMALAAALVLSLTFVPAAVAMFVT----GKVQEKESFV-------MRGARKVYEPILKLAIKA-RYALVGIA 544
Cdd:PRK10555 467 YRQFSITIVSAMVLSVLVAMILTPALCATLLKplkkGEHHGQKGFFgwfnrmfNRNAERYEKGVAKILHRSlRWILIYVL 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 545 IVLVVlsGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARL--KKFPEVERVFAKIGTAEVATDPmpp 622
Cdd:PRK10555 547 LLGGM--VFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYftHEKDNVMSVFATVGSGPGGNGQ--- 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 623 SVADTFVILKDRKKWPNPNEPKNSLVERMQKAVEEIPGNNYEFTQPiqmrfnELISGVRSDVAVKIFGDD-----LDQLL 697
Cdd:PRK10555 622 NVARMFIRLKDWDERDSKTGTSFAIIERATKAFNKIKEARVIASSP------PAISGLGSSAGFDMELQDhagagHDALM 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 698 KTGNDIQKVMKTIPGAEDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPE 777
Cdd:PRK10555 696 AARNQLLALAAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAA 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 778 TQRANLAEIGRLRIPvsndgDSAEGMtgasfIPLQDVAHIEMINGPNQISREQGKRRV-VVTANVRGADLGTFVTTLQDK 856
Cdd:PRK10555 776 PYRMLPDDINLWYVR-----NKDGGM-----VPFSAFATSRWETGSPRLERYNGYSAVeIVGEAAPGVSTGTAMDIMESL 845
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 857 VGaqvKLPEGYWVNY-GGTFEQMTSAAKrlqivVPIALILIIGLLFMLFGTM-EDALIVFSG---VPLALTGGIVALAIR 931
Cdd:PRK10555 846 VK---QLPNGFGLEWtAMSYQERLSGAQ-----APALYAISLLVVFLCLAALyESWSVPFSVmlvVPLGVIGALLATWMR 917
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 932 DIPLSISAGVGFIALSGVAVLNGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQ 1011
Cdd:PRK10555 918 GLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQ 997
|
1050 1060
....*....|....*....|....*....
gi 503246615 1012 RPLATVVIGGIVSSTILTLLILPALYRIV 1040
Cdd:PRK10555 998 HAVGTGVMGGMISATILAIFFVPLFFVLV 1026
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
10-1045 |
5.72e-57 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 214.31 E-value: 5.72e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 10 IRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRYG 89
Cdd:PRK09579 8 IRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 90 LSQVTVVFKEGTDiyfARQLVNE---RVQSVRSQLPAGSEPQLGPISTGLGEIFMYTVEAKPDARKADGTAYTPEdlrtl 166
Cdd:PRK09579 88 FSIISIYARIGAD---SDRLFTEllaKANEVKNQLPQDAEDPVLSKEAADASALMYISFYSEEMSNPQITDYLSR----- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 167 qdwVIRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEksGEQFLVRVpgQANT 246
Cdd:PRK09579 160 ---VIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK--GEYVVTSI--NAST 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 247 ----IEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPE 322
Cdd:PRK09579 233 elksAEAFAAIPVKTSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 323 GVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGA-- 400
Cdd:PRK09579 313 NLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAmv 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 401 LDFGLIVDGAVIIMENCLRRFAEAQhhhgrlltrdERFALASKASTEVIKPSLFGVLIITIVYFPIFALSGVEGKMFHPM 480
Cdd:PRK09579 393 LAIGLVVDDAIVVVENIHRHIEEGK----------SPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEF 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 481 AATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESF-----VMRGARKVYEPILKLAIKARYALVGIAIVLVVLSGFLA 555
Cdd:PRK09579 463 ALTLAGAVIISGIVALTLSPMMCALLLRHEENPSGLAhrldrLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLL 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 556 TRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVFAKIGTAEVAtdpmppSVADTFVIlkdrK 635
Cdd:PRK09579 543 KFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQ------SGIGGFLL----K 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 636 KWPNPNEPKNSLVERMQKAVEEIPGnnyeftqpiqmrfnelisgvrsdvaVKIFGDDLDQLLKTGNDI--QKVMKTIPGA 713
Cdd:PRK09579 613 PWNERERTQMELLPLVQAKLEEIPG-------------------------LQIFGFNLPSLPGTGEGLpfQFVINTANDY 667
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 714 EDV-----RVEQ---VSG------------LPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIV 773
Cdd:PRK09579 668 ESLlqvaqRVKQraqESGkfafldidlafdKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIA 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 774 RLPETQRANLAEIGRLRIpvsnDGDSAEGMTGASFIPLQDVAHiemingPNQISREQGKRRVVVTAnVRGADLGTFVTTL 853
Cdd:PRK09579 748 QVERPYRDNPGWLNNYYV----KNEQGQLLPLSTLITLSDRAR------PRQLNQFQQLNSAIISG-FPIVSMGEAIETV 816
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 854 QDKvgAQVKLPEGYWVNYGGTFEQMTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDI 933
Cdd:PRK09579 817 QQI--AREEAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVS 894
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 934 PLSISAGVGFIALSGVAVLNGVVMLTFIKSLRAEGKL-LDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQR 1012
Cdd:PRK09579 895 SMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLsRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRF 974
|
1050 1060 1070
....*....|....*....|....*....|...
gi 503246615 1013 PLATVVIGGIVSSTILTLLILPALYRIVHGKEK 1045
Cdd:PRK09579 975 DIGLVIATGMSIGTLFTLFVLPCIYTLLAKPDA 1007
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
21-1037 |
1.01e-52 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 201.11 E-value: 1.01e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 21 LALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRYGLSQVTVVFKEG 100
Cdd:PRK10614 19 LAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILQFDFD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 101 TDIYFARQLVNERVQSVRSQLPAG--SEPQLGPISTGLGEIFMYTVEAkpdarkadgTAYTPEDLRTLQDWVIRPQLRNT 178
Cdd:PRK10614 99 RDINGAARDVQAAINAAQSLLPSGmpSRPTYRKANPSDAPIMILTLTS---------DTYSQGQLYDFASTQLAQTISQI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 179 PGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRVPGQANTIEDLKQIVVQTR 258
Cdd:PRK10614 170 DGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLIIHYN 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 259 MGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPEGVSAVSVYDRTTLVER 338
Cdd:PRK10614 250 NGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPTIRA 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 339 TIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGALDF--GLIVDGAVIIMEN 416
Cdd:PRK10614 330 SLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIatGFVVDDAIVVLEN 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 417 cLRRFAEAQHhhgrlltrdERFALASKASTEVikpsLFGVLIITI----VYFPIFALSGVEGKMFHPMAATVVMALAAAL 492
Cdd:PRK10614 410 -ISRHLEAGM---------KPLQAALQGVREV----GFTVLSMSLslvaVFLPLLLMGGLPGRLFREFAVTLSVAIGISL 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 493 VLSLTFVPAAVAMFVTGKVQEKESFVmRGARKV-------YEPILKLAIK-ARYALVgIAIVLVVLSGFLATRLGAEFIP 564
Cdd:PRK10614 476 LVSLTLTPMMCAWLLKSSKPREQKRL-RGFGRMlvalqqgYGRSLKWVLNhTRWVGV-VLLGTIALNVWLYISIPKTFFP 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 565 QLDEGDValhamrIPGTSLTQSIHMQaAVEARLKKF-------PEVERVFAKIGTAEVATDPMppsvadtFVILKDRKKw 637
Cdd:PRK10614 554 EQDTGRL------MGFIQADQSISFQ-AMRGKLQDFmkiirddPAVDNVTGFTGGSRVNSGMM-------FITLKPLSE- 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 638 pnPNEPKNSLVERMQKAVEEIPGNNYeFTQPIQmrfnELISGVRSDVA---VKIFGDDLDQLLKTGNDIQKVMKTIPGAE 714
Cdd:PRK10614 619 --RSETAQQVIDRLRVKLAKEPGANL-FLMAVQ----DIRVGGRQSNAsyqYTLLSDDLAALREWEPKIRKALAALPELA 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 715 DVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRANLAEIGRLRIpVS 794
Cdd:PRK10614 692 DVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFV-IN 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 795 NDGDSaegmtgasfIPLQDVAHIEMINGPNQISREQGKRRVVVTANV-RGADLGTFVTTLqDKVGAQVKLPEGYWVNYGG 873
Cdd:PRK10614 771 NEGKA---------IPLSYFAKWQPANAPLSVNHQGLSAASTISFNLpTGKSLSDASAAI-ERAMTQLGVPSTVRGSFAG 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 874 TFEQMTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVFSGVPLALTGGIVALAIRDIPLSISAGVGFIALSGVAVLN 953
Cdd:PRK10614 841 TAQVFQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKN 920
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 954 GVVMLTFIKSLRAEGKL-LDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLI 1032
Cdd:PRK10614 921 AIMMVDFALEAQRNGNLtAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYT 1000
|
....*
gi 503246615 1033 LPALY 1037
Cdd:PRK10614 1001 TPVVY 1005
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
14-1055 |
3.51e-52 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 199.74 E-value: 3.51e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 14 WIVMIVVLALSALGVynfTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSIS-RYGLSQ 92
Cdd:PRK15127 13 WVIAIIIMLAGGLAI---LKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 93 VTVVFKEGTDIYFARQLVNERVQSVRSQLPAGSEPQLGPISTGLGEIFMYTveakpDARKADGTAyTPEDLRTLQDWVIR 172
Cdd:PRK15127 90 ITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVV-----GVINTDGTM-TQEDISDYVAANMK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 173 PQLRNTPGVTEVNTIGGferQYHVTPF--PERLSAYSLTMADVIKALETNNSNRGAGYVEKS----GEQFLVRVPGQA-- 244
Cdd:PRK15127 164 DPISRTSGVGDVQLFGS---QYAMRIWmnPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTppvkGQQLNASIIAQTrl 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 245 NTIEDLKQIVVQTRM-GVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPEG 323
Cdd:PRK15127 241 TSTEEFGKILLKVNQdGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 324 VSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSL--GAL 401
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMfgMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 402 DFGLIVDGAVIIMENCLRRFAEAQhhhgrlLTRDErfalASKASTEVIKPSLFGV-LIITIVYFPIFALSGVEGKMFHPM 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEG------LPPKE----ATRKSMGQIQGALVGIaMVLSAVFVPMAFFGGSTGAIYRQF 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 481 AATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESFVMRGARKVYEPILK-------------LAIKARYALvgIAIVL 547
Cdd:PRK15127 471 SITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEksthhytdsvgniLRSTGRYLV--LYLII 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 548 VVLSGFLATRLGAEFIPQLDEGdVALHAMRIPGTSL---TQSIHMQAAVEARLKKFPEVERVFAKIGTAeVATDPMPPSV 624
Cdd:PRK15127 549 VVGMAYLFVRLPSSFLPDEDQG-VFLTMVQLPAGATqerTQKVLNEVTDYYLTKEKNNVESVFAVNGFG-FAGRGQNTGI 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 625 AdtFVILKDRKKWPNPNEPKNSLVERMQKAVEEIP-GNNYEFTQPIQMrfnELISGVRSDVA-VKIFGDDLDQLLKTGND 702
Cdd:PRK15127 627 A--FVSLKDWADRPGEENKVEAITMRATRAFSQIKdAMVFAFNLPAIV---ELGTATGFDFElIDQAGLGHEKLTQARNQ 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 703 IQKVMKTIPGA-EDVRVEQVSGLPMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQRA 781
Cdd:PRK15127 702 LLGEAAKHPDMlVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRM 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 782 NLAEIGRLRIPVSNdgdsaegmtgASFIPLQDVAHIEMINGPNQISREQGKRRV-VVTANVRGADLGTFVTTLQDKVGaq 860
Cdd:PRK15127 782 LPDDIGDWYVRAAD----------GQMVPFSAFSSSRWEYGSPRLERYNGLPSMeILGQAAPGKSTGEAMELMEELAS-- 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 861 vKLPEGYWVNYGG-TFEQMTSAAKrlqivVPIALILIIGLLFMLFGTM-EDALIVFS---GVPLALTGGIVALAIRDIPL 935
Cdd:PRK15127 850 -KLPTGVGYDWTGmSYQERLSGNQ-----APALYAISLIVVFLCLAALyESWSIPFSvmlVVPLGVIGALLAATFRGLTN 923
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 936 SISAGVGFIALSGVAVLNGVVMLTFIKSL-RAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQRPL 1014
Cdd:PRK15127 924 DVYFQVGLLTTIGLSAKNAILIVEFAKDLmDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAV 1003
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*
gi 503246615 1015 ATVVIGGIVSSTILTLLILPALYRIVH----GKEKTLEKNRPAPN 1055
Cdd:PRK15127 1004 GTGVMGGMVTATVLAIFFVPVFFVVVRrrfsRKNEDIEHSHTVDH 1048
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
15-1037 |
6.61e-48 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 186.09 E-value: 6.61e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 15 IVMIVVLALSALGvYNFtrLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYTRSISRYGLSQVT 94
Cdd:PRK10503 25 LLMVAILLAGIIG-YRA--LPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVIT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 95 VVFKEGTDIYFARQLVNERVQSVRSQLP---------AGSEPQLGPISTglgeiFMYTVEAKPdarkadgtaytpedLRT 165
Cdd:PRK10503 102 LQFQLTLPLDVAEQEVQAAINAATNLLPsdlpnppvySKVNPADPPIMT-----LAVTSTAMP--------------MTQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 166 LQDWV---IRPQLRNTPGVTEVNTIGGFERQYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGYVEKSGEQFLVRVPG 242
Cdd:PRK10503 163 VEDMVetrVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSAND 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 243 QANTIEDLKQIVVQTRMGVPIRIADVADVLLGEELRTGAATQNGKEVVVATVNMLIGENSRTVAKAVSEKLAAANKSLPE 322
Cdd:PRK10503 243 QMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 323 GVSAVSVYDRTTLVERTIQTIEKNLAEGALLVIVILFLLLGNIRAAIITAMVIPVAMLMTITGMVENKVSGNLMSLGALD 402
Cdd:PRK10503 323 SVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALT 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 403 F--GLIVDGAVIIMENClrrfaeaqhhhGRLLTRDER-FALASKASTEV------IKPSLFGVLIitivyfPIFALSGVE 473
Cdd:PRK10503 403 IatGFVVDDAIVVIENI-----------SRYIEKGEKpLAAALKGAGEIgftiisLTFSLIAVLI------PLLFMGDIV 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 474 GKMFHPMAATVVMALAAALVLSLTFVPAAVAMFVTGKVQEKESFVMRGARKVYEPI-------LKLAIKARYALVGIAIV 546
Cdd:PRK10503 466 GRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASERMFDRViaaygrgLAKVLNHPWLTLSVALS 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 547 LVVLSGFLATRLGAEFIPQLDEGDVALHAMRIPGTSLTQSIHMQAAVEARLKKFPEVERVfakigTAEVATDPMPPSVAD 626
Cdd:PRK10503 546 TLLLTVLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSL-----TSFVGVDGTNPSLNS 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 627 -----TFVILKDRkkwpnpNEPKNSLVERMQKAVEEIPGNNYeFTQPIQ-MRFNELISgvRSDVAVKIFGDDLDQLLKTG 700
Cdd:PRK10503 621 arlqiNLKPLDER------DDRVQKVIARLQTAVAKVPGVDL-YLQPTQdLTIDTQVS--RTQYQFTLQATSLDALSTWV 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 701 NDIQKVMKTIPGAEDVRVE-QVSGLpMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVRLPETQ 779
Cdd:PRK10503 692 PKLMEKLQQLPQLSDVSSDwQDKGL-VAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTEN 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 780 RANLAEIGRLRIpVSNDGDSaegmtgasfIPLQDVAHIEMINGPNQISREQGKRRVVVTANVR-GADLGTFVTTLQDkVG 858
Cdd:PRK10503 771 TPGLAALDTIRL-TSSDGGV---------VPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPdGYSLGDAVQAIMD-TE 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 859 AQVKLPEGYWVNYGGTFEQMTSA-AKRLQIVVpialiLIIGLLFMLFGTMEDALI----VFSGVPLALTGGIVALAIRDI 933
Cdd:PRK10503 840 KTLNLPADITTQFQGSTLAFQSAlGSTVWLIV-----AAVVAMYIVLGVLYESFIhpitILSTLPTAGVGALLALMIAGS 914
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 934 PLSISAGVGFIALSGVAVLNGVVMLTF-IKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASLGFVPMAFNVGAGSEVQR 1012
Cdd:PRK10503 915 ELDVIAIIGIILLIGIVKKNAIMMIDFaLAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRR 994
|
1050 1060
....*....|....*....|....*
gi 503246615 1013 PLATVVIGGIVSSTILTLLILPALY 1037
Cdd:PRK10503 995 PLGICMVGGLIVSQVLTLFTTPVIY 1019
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-325 |
5.28e-21 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 99.41 E-value: 5.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 3 EKIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYT 82
Cdd:COG0841 516 GRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESV 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 83 RSISRYGLS-------QVTVVFKEGTDIYFARQLVNERVQSVRSQLPAG----SEPQLGPISTGLGeiFMYTVEAkpdar 151
Cdd:COG0841 596 FSVVGFSGGgsgsnsgTIFVTLKPWDERDRSADEIIARLREKLAKIPGArvfvFQPPAGGLGSGAP--IEVQLQG----- 668
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 152 kadgtaytpEDLRTLQDWV--IRPQLRNTPGVTEVNTIGGFER-QYHVTPFPERLSAYSLTMADVIKALETNNSNRGAGY 228
Cdd:COG0841 669 ---------DDLEELAAAAekLLAALRQIPGLVDVRSDLQLGKpELQLDIDREKAAALGVTVADVASTLRAALGGRYVND 739
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 229 VEKSGEQFLVRV---PGQANTIEDLKQIVVQTRMGVPIRIADVADVllgeELRTGAAT---QNGKEVVVATVNMLIGENS 302
Cdd:COG0841 740 FNRGGREYDVRVqapEEDRNSPEDLENLYVRTPDGEMVPLSSVATI----EEGTGPSSinrYNGQRSVTVSANLAPGVSL 815
|
330 340
....*....|....*....|...
gi 503246615 303 RTVAKAVSEklAAANKSLPEGVS 325
Cdd:COG0841 816 GEALAAIEE--LAAELKLPPGVS 836
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
701-1051 |
3.17e-12 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 70.90 E-value: 3.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 701 NDIQKVMKTIPGAEDVrveQVSGL--PMLQITPDRTAMARLGLSIGDVQDVVSTALGGTEAGQIFEGDRRFNVIVrlpET 778
Cdd:COG0841 159 RNIKDRLERVPGVGQV---QIFGGreREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRT---NG 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 779 QRANLAEIGRLRIPVSNDgdsaegmtgaSFIPLQDVAHIEM-INGPNQISREQGKRrvVVTANVR---GADlgtfVTTLQ 854
Cdd:COG0841 233 RLKTPEEFENIVIRTNDG----------SVVRLGDVARVEDgAEDYRSIARLNGKP--AVGLAIQkqpGAN----ALEVA 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 855 DKVGAQVK-----LPEGywVNYGGTFEQMTSAAKRLQIVVpialiliigllFMLFgtmEDALIVFSGVPLALTGG----I 925
Cdd:COG0841 297 DAVRAKLEelqasLPEG--VELTIVYDQSEFIRASIEEVV-----------KTLL---EAILLVVLVVFLFLRSWratlI 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 926 VALAIrdiPLSISAGVGFIALSGVA---------VL-------NGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMT 989
Cdd:COG0841 361 PAVAI---PVSLIGTFAVMYLLGFSlniltlfalVLaigivvdDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIAS 437
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 503246615 990 ALVASLGFVPMAFNVGAGSEVQRPLATVVIGGIVSSTILTLLILPALYRIVHGKEKTLEKNR 1051
Cdd:COG0841 438 TLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTPALCARLLKPHPKGKKGR 499
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
917-1045 |
5.22e-06 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 50.63 E-value: 5.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 917 VPLALTGGIVALAirDIPLSIS-AGVGFIALsGVAVLNGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTALVASL 995
Cdd:COG1033 641 LPILLTFGLMGLL--GIPLNIAtAVVASIAL-GIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAA 717
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 503246615 996 GFVPMAFnvgAGSEVQRPLATVVIGGIVSSTILTLLILPALYRIVHGKEK 1045
Cdd:COG1033 718 GFGVLLF---SSFPPLADFGLLLALGLLVALLAALLLLPALLLLLDPRIA 764
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
876-1055 |
8.86e-06 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 49.86 E-value: 8.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 876 EQMTSAAKRLQIVVPIALILIIGLLFMLFGTMEDALIVF--SGVPLALTGGIVALAirDIPLSISAGVGFIALSGVAVLN 953
Cdd:COG1033 211 DIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLlvVLLAVIWTLGLMGLL--GIPLSPLTILVPPLLLAIGIDY 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 954 GVVMLTFIKSLRAEGKLLDDAIIEgALTRL-RPVMMTALVASLGFVPMAFnvgAGSEVQRPLATVVIGGIVSSTILTLLI 1032
Cdd:COG1033 289 GIHLLNRYREERRKGLDKREALRE-ALRKLgPPVLLTSLTTAIGFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTL 364
|
170 180
....*....|....*....|...
gi 503246615 1033 LPALYRIVHGKEKTLEKNRPAPN 1055
Cdd:COG1033 365 LPALLSLLPRPKPKTRRLKKPPE 387
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
912-1050 |
2.99e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 48.29 E-value: 2.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 912 IVFSGVplALTGGIvaLAIRDIPLSISAGVGFIALSGVAVLNGVVMLTFIKSLRAEGKLLDDAIIEGALTRLRPVMMTAL 991
Cdd:TIGR00921 226 IILFGV--AWVLGI--MGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALL 301
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 992 VASLGFVPMAFNVgaGSEVQRpLATVVIGGIVSSTILTLLILPA-LYRIVHGKEKTLEKN 1050
Cdd:TIGR00921 302 TTSAGFAALALSE--FPMVSE-FGLGLVAGLITAYLLTLLVLPAlLQSIDIGREKVKKEI 358
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
3-271 |
1.28e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 43.08 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 3 EKIIAQSIRHRWIVMIVVLALSALGVYNFTRLPIDAVPDITNVQVQINTEAPGYSPLEAEQRITFPVETAIAGLPGLQYT 82
Cdd:NF033617 513 GRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSL 592
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 83 RSISRYGLSQ------VTVVFKEGTDIYFARQLVNERVQSVRSQLPaGSEP-----QLGPISTGLG-EIFMYTVeakpda 150
Cdd:NF033617 593 TSFNGVGGNPgdntgfGIINLKPWDERDVSAQEIIDRLRPKLAKVP-GMDLflfplQDLPGGAGSSlPQYQVTL------ 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503246615 151 rkadgtayTPEDLRTLQDWV--IRPQLRNTPGVTEVNTIGGFER-QYHVTPFPERLSAYSLTMADVIKALETNNSNRGAG 227
Cdd:NF033617 666 --------TPSDYDSLFTWAekLKEKLRKSPQFADVDSDLQDKGpELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVN 737
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 503246615 228 YVEKSGEQFLV--RV-PGQANTIEDLKQIVVQTRMGVPIRIADVADV 271
Cdd:NF033617 738 TIYTDGNQYKVvlEVdRRYRLNPEALNQIYVRSNDGKLVPLSTLAKI 784
|
|
| |
