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Conserved domains on  [gi|503251550|ref|WP_013486211|]
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ABC transporter permease [Ethanoligenens harbinense]

Protein Classification

ABC transporter permease( domain architecture ID 10003065)

ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of substrates including gylcine betaine, choline, and carnitine

Gene Ontology:  GO:0140359|GO:0042626|GO:0055085|GO:0016020
PubMed:  25750732|24638992|31571164|27273632|26517919|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 3-193 4.79e-70

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 211.84  E-value: 4.79e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   3 DFINTILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSL 82
Cdd:COG1174   15 GILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAIIALVLYAL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  83 LPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQ 162
Cdd:COG1174   95 LPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGGLGDLIFDGLQ 174

                        170       180       190
                 ....*....|....*....|....*....|.
gi 503251550 163 ALDWGMIIEGTIPVVLLSLLAQYVFNKLQRL 193
Cdd:COG1174  175 LNNTALILAGAILVALLALLVDLLLALLERL 205
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 3-193 4.79e-70

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 211.84  E-value: 4.79e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   3 DFINTILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSL 82
Cdd:COG1174   15 GILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAIIALVLYAL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  83 LPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQ 162
Cdd:COG1174   95 LPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGGLGDLIFDGLQ 174

                        170       180       190
                 ....*....|....*....|....*....|.
gi 503251550 163 ALDWGMIIEGTIPVVLLSLLAQYVFNKLQRL 193
Cdd:COG1174  175 LNNTALILAGAILVALLALLVDLLLALLERL 205
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
12-182 4.78e-23

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 94.39  E-value: 4.78e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  12 LAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSLLPVIRNTYT 91
Cdd:PRK10952 150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTIL 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  92 GLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQALDWGMIIE 171
Cdd:PRK10952 230 GINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATV 309

                        170
                 ....*....|.
gi 503251550 172 GTIPVVLLSLL 182
Cdd:PRK10952 310 GGVGIVILAII 320
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 22-193 8.19e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.86  E-value: 8.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   22 AVLIGTLAGIWISRKTAFAgpVLYIADVIQTIPSLALLAIL-----MIVFGLGDLTVIIGLCLYSLLPVIRNTYTGLTAI 96
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRL--LRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   97 PPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSG-GLGYIIYRGIQALDWGMIIEGTIP 175
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLA 158

                         170
                  ....*....|....*...
gi 503251550  176 VVLLSLLAQYVFNKLQRL 193
Cdd:pfam00528 159 AALILLLLNLLVDILQRL 176
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 8-179 1.84e-10

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 58.32  E-value: 1.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550    8 ILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFA----GPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSLL 83
Cdd:TIGR01097  60 LLETLAMAILGTVLAAVLAVPLALLAARNITPSpwlyGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVG 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   84 PVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQA 163
Cdd:TIGR01097 140 FLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAGGIGLELDTAIGL 219

                         170
                  ....*....|....*....
gi 503251550  164 LDW---GMIIEGTIPVVLL 179
Cdd:TIGR01097 220 FDYdevSAIILVILVVVVI 238
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 8-182 1.83e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.98  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   8 ILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLY-IADVIQTIPSLALLAILMIVFGL---------GDLTVIIGL 77
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRrIIDLLLSLPSLVLGLLLVLLFGVllgwgilpgLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  78 CLYSLLPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYII 157
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....*
gi 503251550 158 YRGIQALDWGMIIEGTIPVVLLSLL 182
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALIL 185
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 3-193 4.79e-70

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 211.84  E-value: 4.79e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   3 DFINTILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSL 82
Cdd:COG1174   15 GILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAIIALVLYAL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  83 LPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQ 162
Cdd:COG1174   95 LPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGGLGDLIFDGLQ 174

                        170       180       190
                 ....*....|....*....|....*....|.
gi 503251550 163 ALDWGMIIEGTIPVVLLSLLAQYVFNKLQRL 193
Cdd:COG1174  175 LNNTALILAGAILVALLALLVDLLLALLERL 205
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 7-193 2.12e-28

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 106.77  E-value: 2.12e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   7 TILEHLAMT----AAGVAIAVLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSL 82
Cdd:COG0600   58 ELWEHLLASllrvLLGFALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAF 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  83 LPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSG-GLGYIIYRGI 161
Cdd:COG0600  138 FPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASsGLGYLILDAR 217

                        170       180       190
                 ....*....|....*....|....*....|..
gi 503251550 162 QALDWGMIIEGTIPVVLLSLLAQYVFNKLQRL 193
Cdd:COG0600  218 QLLDTDLVFAAILVIGLLGLLLDLLLRLLERR 249
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
12-182 4.78e-23

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 94.39  E-value: 4.78e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  12 LAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSLLPVIRNTYT 91
Cdd:PRK10952 150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTIL 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  92 GLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQALDWGMIIE 171
Cdd:PRK10952 230 GINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATV 309

                        170
                 ....*....|.
gi 503251550 172 GTIPVVLLSLL 182
Cdd:PRK10952 310 GGVGIVILAII 320
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 22-193 8.19e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.86  E-value: 8.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   22 AVLIGTLAGIWISRKTAFAgpVLYIADVIQTIPSLALLAIL-----MIVFGLGDLTVIIGLCLYSLLPVIRNTYTGLTAI 96
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRL--LRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   97 PPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSG-GLGYIIYRGIQALDWGMIIEGTIP 175
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLA 158

                         170
                  ....*....|....*...
gi 503251550  176 VVLLSLLAQYVFNKLQRL 193
Cdd:pfam00528 159 AALILLLLNLLVDILQRL 176
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 8-192 1.17e-11

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 61.64  E-value: 1.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   8 ILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLYIA----DVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSLL 83
Cdd:COG3639   53 LLETLAIALLGTLLGAVLALPLAFLAARNLAPNPWVRLLArrllNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIG 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  84 PVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQA 163
Cdd:COG3639  133 FLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIGLLLNEAIRL 212

                        170       180
                 ....*....|....*....|....*....
gi 503251550 164 LDWGMIIEGTIPVVLLSLLAQYVFNKLQR 192
Cdd:COG3639  213 FQYDEVAAILLVILVLVLLIDLLSARLRR 241
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 6-192 6.63e-11

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 59.66  E-value: 6.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   6 NTILEHLAMTAAGVAIAVLIGTLAGIWIS---RKTAFAGPVLYIADVIQTIPS----LALLAILMIVFGLGD--LTVIIG 76
Cdd:COG0581   41 PAIVGTLLLVLLATLIAVPLGVLAAIYLAeyaRGGRLARLIRFAIDVLAGVPSivygLFGYALFVLTLGLGFslLAGALA 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  77 LCLYSLLPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGI-----RIA------FVTALGTAVIG 145
Cdd:COG0581  121 LALLMLPVVIRTTEEALRLVPNSLREASYALGATKWQTIRKVVLPAALPGILTGVilaiaRAAgetaplLFTAGVSPFLP 200

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 503251550 146 VLIGSGG--LGYIIYRGI-------QALDWGMIIEGTIPVVLLSLLAQYVFNKLQR 192
Cdd:COG0581  201 LSLFDPFatLPVHIYNLAsspypaaQELAWAAALVLLLLVLLLNLLARLLRRRFRK 256
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 16-152 9.65e-11

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 59.35  E-value: 9.65e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  16 AAGVAIAVLIGTLAGIWISR-KTAFAGPVLYIADVIQTIPSLAL---LAILMIVFGLGD--LTVIIGLCLYSLLPVIRNT 89
Cdd:COG1177   71 LLSTLLATVLGTPAALALARyRFRGRRLLLALLLLPLVVPGIVLgvaLLLLFSALGLSGglWGLILAHVVFTLPFVVLVV 150

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503251550  90 YTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGG 152
Cdd:COG1177  151 LARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPG 213
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 8-179 1.84e-10

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 58.32  E-value: 1.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550    8 ILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFA----GPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSLL 83
Cdd:TIGR01097  60 LLETLAMAILGTVLAAVLAVPLALLAARNITPSpwlyGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVG 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   84 PVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIYRGIQA 163
Cdd:TIGR01097 140 FLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAGGIGLELDTAIGL 219

                         170
                  ....*....|....*....
gi 503251550  164 LDW---GMIIEGTIPVVLL 179
Cdd:TIGR01097 220 FDYdevSAIILVILVVVVI 238
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-192 1.90e-10

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 59.02  E-value: 1.90e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  12 LAMTAAGVAIAVLIGTLAGIWISR-KTAFAGPVLYIADVIQTIPS----LALLAILMIVFGL---GDLTVIIGLCLYSLL 83
Cdd:COG1178  344 LLLALLAALLAVLLALLLAYLVRRrRGRLARLLDRLAMLPYAVPGivlgLGLLLLFNRPLPLllyGTLAILVLAYVVRFL 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  84 PV-IRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGG---LGYIIYR 159
Cdd:COG1178  424 PFaLRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGfetLAVLIYQ 503

                        170       180       190
                 ....*....|....*....|....*....|...
gi 503251550 160 GIQALDWGMIIEGTIPVVLLSLLAQYVFNKLQR 192
Cdd:COG1178  504 LASSGRYGEAAALALLLVLVSLLPVLLLERLLG 536
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
10-196 4.83e-10

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 57.25  E-value: 4.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  10 EHLAMTAAGVAIAVLIGTLAGI---WISRKTAFAGPVLYIA-DVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSLLPV 85
Cdd:PRK11365  60 QHLAISSWRALIGFSIGGSLGLilgLISGLSRWGERLLDTSiQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPI 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  86 IRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLI-GSGGLGYIIYRGIQAL 164
Cdd:PRK11365 140 YINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETIsANSGIGYLAMNAREFL 219

                        170       180       190
                 ....*....|....*....|....*....|..
gi 503251550 165 DWGMIIEGTIPVVLLSLLAQYVFNKLQRLEKR 196
Cdd:PRK11365 220 QTDVVVVAIILYALLGKLADVSAQLLERLWLR 251
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 4-198 1.04e-09

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 56.31  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   4 FINTILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVF------------GLG-- 69
Cdd:COG1176   65 YLKVLLRTLWIALLTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLlgrngllnslllALGli 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  70 ---------DLTVIIGLClYSLLP-VIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTAL 139
Cdd:COG1176  145 deplrllytEFAVVIGLV-YVYLPfMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPAL 223

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503251550 140 GTAVIGVLIGSGG---LGYIIY-RGIQALDWGMIIEGTIPVVLLSLLAQYVFNKLQRLEKRRK 198
Cdd:COG1176  224 GAFVTPALLGGGKvlmIGNLIYqQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRLLG 286
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 8-182 1.83e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.98  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   8 ILEHLAMTAAGVAIAVLIGTLAGIWISRKTAFAGPVLY-IADVIQTIPSLALLAILMIVFGL---------GDLTVIIGL 77
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRrIIDLLLSLPSLVLGLLLVLLFGVllgwgilpgLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  78 CLYSLLPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSGGLGYII 157
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180
                 ....*....|....*....|....*
gi 503251550 158 YRGIQALDWGMIIEGTIPVVLLSLL 182
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALIL 185
PRK10160 PRK10160
taurine ABC transporter permease TauC;
7-192 3.24e-09

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 55.18  E-value: 3.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   7 TILEHLAMTAAGVAIA----VLIGTLAGIWISRKTAFAGPVLYIADVIQTIPSLALLAILMIVFGLGDLTVIIGLCLYSL 82
Cdd:PRK10160  75 TLWQHLAASLTRIVLAllaaVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIF 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  83 LPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSG-GLGYIIYRGI 161
Cdd:PRK10160 155 APVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATrGLGFMVQSAG 234

                        170       180       190
                 ....*....|....*....|....*....|.
gi 503251550 162 QALDWGMIIEGTIPVVLLSLLAQYVFNKLQR 192
Cdd:PRK10160 235 EFLATDVVLAGIAVIAIIAFLLELGLRALQR 265
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 12-128 1.82e-06

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 46.61  E-value: 1.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  12 LAMTAAGVAIAVLIGTLAGIW-ISRKTAFAGPVLYIADVIQTIPSLALLaiLMIVFGLGDL--------TVIIGLCLYS- 81
Cdd:COG0765   23 LLLTVLAIVLGLVLGLLLALArLSPNPVLRWLATAYVEFFRGTPLLVQL--FFIYFGLPLLgidlspfvAAVIALTLNSa 100

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 503251550  82 --LLPVIRntyTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMIL 128
Cdd:COG0765  101 ayLAEIVR---AGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIIL 146
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 4-184 2.58e-06

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 46.68  E-value: 2.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   4 FINTILehlaMTAAGVAIAVLIGTLAGIWISRKTaFAG--PVLYIADVIQTIPS-LALLAILMIVFGLGDLTVIIGL-CL 79
Cdd:COG3833   75 FLNSLI----VAVVTAIISVFLAALAAYAFSRFR-FKGrkAGLLALLLLQMFPAfLALVALYLLLSALGLLNTLLGLiLV 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  80 YSLLPVIRNTYTG---LTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVI-GVLIGSG---- 151
Cdd:COG3833  150 YLGGAIPFNTWLMkgyFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILaSVLLRSPenyt 229

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 503251550 152 ---GLGYIIYRGIQALdWGMIIEG----TIPVVLLSLLAQ 184
Cdd:COG3833  230 lavGLYSFVSDQRNTN-WGVFAAGavlvAIPIVILFLFLQ 268
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
1-159 4.22e-06

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 45.49  E-value: 4.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   1 MLDFINTILEHLAMTAAGVAIAVLIGTLAGI--WISRK-TAFAGPVLY-----IADVIQTIPSLALLaILMIVF------ 66
Cdd:PRK10782   6 MWLLVRGVWETLAMTFVSGFFGFVIGLPVGVllYVTRPgQIIANAKLYrtlsaLVNIFRSIPFIILL-VWMIPFtrvivg 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  67 -GLGDLTVIIGLCLYSLLPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIG 145
Cdd:PRK10782  85 tSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMG 164

                        170
                 ....*....|....
gi 503251550 146 VLIGSGGLGYIIYR 159
Cdd:PRK10782 165 GAVGAGGLGQIGYQ 178
pstA PRK11268
phosphate ABC transporter permease PstA;
6-138 4.38e-05

phosphate ABC transporter permease PstA;


Pssm-ID: 183065 [Multi-domain]  Cd Length: 295  Bit Score: 43.13  E-value: 4.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   6 NTILEHLAMTAAGVAIAVLIGTLAGIWIS---RKTAFAGPVLYIADVIQTIPSlallailmIVFGLGDLTV--------- 73
Cdd:PRK11268  81 NAIAGSGLLILWATVVGTPLGIMAGIYLAeygRKSWLAEVIRFINDILLSAPS--------IVVGLFVYTIvvaqmehfs 152

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503251550  74 ----IIGLCLYSLLPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGI-----RIAFVTA 138
Cdd:PRK11268 153 gwagVIALALLQIPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGVllaiaRIAGETA 226
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 85-140 1.03e-04

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 41.66  E-value: 1.03e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 503251550  85 VIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALG 140
Cdd:COG0555  151 VVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALG 206
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-140 3.14e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 40.91  E-value: 3.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  12 LAMTAAGVAIAVLIGTLAGIWISRK---------------------------TAFAGPVLYIADVIQTIPSLALLAIlmi 64
Cdd:COG1178   60 LLLALLVTLLSLLLGVPLAWLLARTdfpgrrllrwllllplalppyvvalawIALFGPNGLLNTLLRALFGLEPPDI--- 136

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503251550  65 vFGLGDLTVIIGLCLYSLlpVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALG 140
Cdd:COG1178  137 -YGLGGIILVLVLFNYPY--VYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLA 209
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 12-144 6.53e-04

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 39.58  E-value: 6.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  12 LAMTAAGVAIAVLIGTLAGIWISR-----KTAFAGPVLYIADVIQTIPSLALLAILMIV-FGLGDLTVIIGLCLYSLLPV 85
Cdd:PRK09500  63 LTMAVFSATFATLIGSLTAVALYRyrfrgKKFVSGMLFVVMMSPDIVMAISLLVLFMLLgIQLGFWSLLFAHITFCLPFV 142

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 503251550  86 IRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVI 144
Cdd:PRK09500 143 VVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSFTLSLDDVVV 201
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 73-151 1.04e-03

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 38.90  E-value: 1.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550  73 VIIGLcLYSLLP-VIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALGTAVIGVLIGSG 151
Cdd:PRK09497 153 VIIGL-VYILLPfMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGA 231
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 45-158 1.48e-03

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 38.40  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503251550   45 YIADVIQTIpsLALLAILMIVFGLGDLTVIIGLCLYSLLPVIRNTYTGLTAIPPSIREAARGMGMSSIQSLIKVELPLAV 124
Cdd:TIGR02138 128 FLKPHFQPF--LGSNLGLIPLFGGPILTAGIVLAIMILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAAR 205

                          90       100       110
                  ....*....|....*....|....*....|....
gi 503251550  125 PMILSGIRIAFVTALGTAVIGVLIGSGGLGYIIY 158
Cdd:TIGR02138 206 SGIVGAVVLGLGRALGETMAVTMVIGNVFPISPL 239
modB PRK09421
molybdate ABC transporter permease subunit;
93-140 6.35e-03

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 36.44  E-value: 6.35e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 503251550  93 LTAIPPSIREAARGMGMSSIQSLIKVELPLAVPMILSGIRIAFVTALG 140
Cdd:PRK09421 115 LEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLG 162
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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