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Conserved domains on  [gi|503565308|ref|WP_013799384|]
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type III-A CRISPR-associated protein Csm2 [Methanotorris igneus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Csm2 COG1421
CRISPR-Cas system type III CSM-effector complex small subunit Csm2 [Defense mechanisms]; ...
 34-149 2.09e-22

CRISPR-Cas system type III CSM-effector complex small subunit Csm2 [Defense mechanisms]; CRISPR-Cas system type III CSM-effector complex small subunit Csm2 is part of the Pathway/BioSystem: CRISPR-Cas system


:

Pssm-ID: 441031  Cd Length: 128  Bit Score: 85.80  E-value: 2.09e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308  34 NDKNIKKFLNYAEEFANK-NLKYISFTKIRKFYDYLNEISPE------DEDWIIKFAHLKPMVAYHYGkekRNQGLFELK 106
Cdd:COG1421   14 KDLDAKLLIDKAEEIGKElKNKKLTTSQIRKFYDEVKRIKNKvkqeelFEELLPELALLKPKLAYAAG---REKEVKEFV 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 503565308 107 KLIDAVFDKIynendeNKRKEMFKHFKKFFEAIIAYKRFYEGK 149
Cdd:COG1421   91 EVLDKAIDKV------KDSEDFFERFVDFFEAIVAYHKFYGGK 127
 
Name Accession Description Interval E-value
Csm2 COG1421
CRISPR-Cas system type III CSM-effector complex small subunit Csm2 [Defense mechanisms]; ...
 34-149 2.09e-22

CRISPR-Cas system type III CSM-effector complex small subunit Csm2 [Defense mechanisms]; CRISPR-Cas system type III CSM-effector complex small subunit Csm2 is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 441031  Cd Length: 128  Bit Score: 85.80  E-value: 2.09e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308  34 NDKNIKKFLNYAEEFANK-NLKYISFTKIRKFYDYLNEISPE------DEDWIIKFAHLKPMVAYHYGkekRNQGLFELK 106
Cdd:COG1421   14 KDLDAKLLIDKAEEIGKElKNKKLTTSQIRKFYDEVKRIKNKvkqeelFEELLPELALLKPKLAYAAG---REKEVKEFV 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 503565308 107 KLIDAVFDKIynendeNKRKEMFKHFKKFFEAIIAYKRFYEGK 149
Cdd:COG1421   91 EVLDKAIDKV------KDSEDFFERFVDFFEAIVAYHKFYGGK 127
Csm2_III-A pfam03750
Csm2 Type III-A; Clusters of short DNA repeats with non-homologous spacers, which are found at ...
 37-146 5.61e-12

Csm2 Type III-A; Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.


Pssm-ID: 461039  Cd Length: 111  Bit Score: 58.42  E-value: 5.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308   37 NIKKFLNYAEEFA-NKNLKYISFTKIRKFYDYLNEI--------SPEDEDWIIKFAHLKPMVAYHYGkekRNQGLFELKK 107
Cdd:pfam03750   1 DIELLVEIAEKIGkELKKKKLTTSQIRKFYDYVRRIeakikqgkEDESEEIQAELNLLKPKLAYAAG---RDEAVKELVE 77

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 503565308  108 LIDAVFDKIYNENDEnkrkemFKHFKKFFEAIIAYKRFY 146
Cdd:pfam03750  78 VLLKAIDKIKDSKED------FKRFVQFFEAIVAYHKYY 110
cas_TM1810_Csm2 TIGR01870
CRISPR type III-A/MTUBE-associated protein Csm2; These proteins are found adjacent to a ...
 59-148 9.36e-11

CRISPR type III-A/MTUBE-associated protein Csm2; These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.


Pssm-ID: 273844  Cd Length: 97  Bit Score: 55.08  E-value: 9.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308   59 TKIRKFYDYLNEISPED-------EDWIIKFAHLKPMVAYHYGKEKR--NQGLFELKKLIDAVFDKIynendENKRKEMF 129
Cdd:TIGR01870   4 TQLRRFYDELRRIEEKIrrseqknEDITAELHMLKPKLAYAVGREGIreFEGFVELLEDLLDKIDKI-----DNDDRRAF 78

                          90
                  ....*....|....*....
gi 503565308  130 KHFKKFFEAIIAYKRFYEG 148
Cdd:TIGR01870  79 ERFVKFFEAIVAYHKFYGG 97
Csm2_III-A cd09647
CRISPR/Cas system-associated protein Csm2; CRISPR (Clustered Regularly Interspaced Short ...
 59-146 4.75e-10

CRISPR/Cas system-associated protein Csm2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-A


Pssm-ID: 187778  Cd Length: 95  Bit Score: 53.14  E-value: 4.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308  59 TKIRKFYDYLNEISPED-------EDWIIKFAHLKPMVAYHYGKEKR--NQGLFELKKLIDAVFDKIynENDENKrkemF 129
Cdd:cd09647    4 TQLRRFYDELRRIEEKIgteekknEDITAELEMLKPKLAYAVGREGVreFEGFVELLEDLLDKIDKI--DNDRNA----F 77

                         90
                 ....*....|....*..
gi 503565308 130 KHFKKFFEAIIAYKRFY 146
Cdd:cd09647   78 ERFVKFFEAIVAYHKFY 94
 
Name Accession Description Interval E-value
Csm2 COG1421
CRISPR-Cas system type III CSM-effector complex small subunit Csm2 [Defense mechanisms]; ...
 34-149 2.09e-22

CRISPR-Cas system type III CSM-effector complex small subunit Csm2 [Defense mechanisms]; CRISPR-Cas system type III CSM-effector complex small subunit Csm2 is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 441031  Cd Length: 128  Bit Score: 85.80  E-value: 2.09e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308  34 NDKNIKKFLNYAEEFANK-NLKYISFTKIRKFYDYLNEISPE------DEDWIIKFAHLKPMVAYHYGkekRNQGLFELK 106
Cdd:COG1421   14 KDLDAKLLIDKAEEIGKElKNKKLTTSQIRKFYDEVKRIKNKvkqeelFEELLPELALLKPKLAYAAG---REKEVKEFV 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 503565308 107 KLIDAVFDKIynendeNKRKEMFKHFKKFFEAIIAYKRFYEGK 149
Cdd:COG1421   91 EVLDKAIDKV------KDSEDFFERFVDFFEAIVAYHKFYGGK 127
Csm2_III-A pfam03750
Csm2 Type III-A; Clusters of short DNA repeats with non-homologous spacers, which are found at ...
 37-146 5.61e-12

Csm2 Type III-A; Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.


Pssm-ID: 461039  Cd Length: 111  Bit Score: 58.42  E-value: 5.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308   37 NIKKFLNYAEEFA-NKNLKYISFTKIRKFYDYLNEI--------SPEDEDWIIKFAHLKPMVAYHYGkekRNQGLFELKK 107
Cdd:pfam03750   1 DIELLVEIAEKIGkELKKKKLTTSQIRKFYDYVRRIeakikqgkEDESEEIQAELNLLKPKLAYAAG---RDEAVKELVE 77

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 503565308  108 LIDAVFDKIYNENDEnkrkemFKHFKKFFEAIIAYKRFY 146
Cdd:pfam03750  78 VLLKAIDKIKDSKED------FKRFVQFFEAIVAYHKYY 110
cas_TM1810_Csm2 TIGR01870
CRISPR type III-A/MTUBE-associated protein Csm2; These proteins are found adjacent to a ...
 59-148 9.36e-11

CRISPR type III-A/MTUBE-associated protein Csm2; These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.


Pssm-ID: 273844  Cd Length: 97  Bit Score: 55.08  E-value: 9.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308   59 TKIRKFYDYLNEISPED-------EDWIIKFAHLKPMVAYHYGKEKR--NQGLFELKKLIDAVFDKIynendENKRKEMF 129
Cdd:TIGR01870   4 TQLRRFYDELRRIEEKIrrseqknEDITAELHMLKPKLAYAVGREGIreFEGFVELLEDLLDKIDKI-----DNDDRRAF 78

                          90
                  ....*....|....*....
gi 503565308  130 KHFKKFFEAIIAYKRFYEG 148
Cdd:TIGR01870  79 ERFVKFFEAIVAYHKFYGG 97
Csm2_III-A cd09647
CRISPR/Cas system-associated protein Csm2; CRISPR (Clustered Regularly Interspaced Short ...
 59-146 4.75e-10

CRISPR/Cas system-associated protein Csm2; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-A


Pssm-ID: 187778  Cd Length: 95  Bit Score: 53.14  E-value: 4.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503565308  59 TKIRKFYDYLNEISPED-------EDWIIKFAHLKPMVAYHYGKEKR--NQGLFELKKLIDAVFDKIynENDENKrkemF 129
Cdd:cd09647    4 TQLRRFYDELRRIEEKIgteekknEDITAELEMLKPKLAYAVGREGVreFEGFVELLEDLLDKIDKI--DNDRNA----F 77

                         90
                 ....*....|....*..
gi 503565308 130 KHFKKFFEAIIAYKRFY 146
Cdd:cd09647   78 ERFVKFFEAIVAYHKFY 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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