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Conserved domains on  [gi|503708030|ref|WP_013942106|]
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tetratricopeptide repeat protein [Corallococcus macrosporus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 708416)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 7-152 1.01e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.78  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030   7 RAARWVAWGLVATLALPSPVWAAGPLERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVA 86
Cdd:COG3914   50 ALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLE 129

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503708030  87 DAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG3914  130 EALAALRRALALNPDFAE--AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDL 193
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 7-152 1.01e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.78  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030   7 RAARWVAWGLVATLALPSPVWAAGPLERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVA 86
Cdd:COG3914   50 ALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLE 129

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503708030  87 DAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG3914  130 EALAALRRALALNPDFAE--AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDL 193
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 106-138 1.15e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 47.44  E-value: 1.15e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 503708030   106 KAWYNLGNLHATTGDRQEALKAYRRALTLDPQD 138
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
106-138 1.31e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 47.03  E-value: 1.31e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 503708030  106 KAWYNLGNLHATTGDRQEALKAYRRALTLDPQD 138
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 109-149 3.05e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 38.11  E-value: 3.05e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 503708030 109 YNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVL 149
Cdd:PRK02603  76 YNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIY 116
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 74-136 8.18e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 37.61  E-value: 8.18e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503708030  74 NRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDP 136
Cdd:cd24142    5 EKAEELLDQGNFELALKFLQRALELEPNNVE--ALELLGEILLELGDVEEAREVLLRAIELDP 65
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 7-152 1.01e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.78  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030   7 RAARWVAWGLVATLALPSPVWAAGPLERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVA 86
Cdd:COG3914   50 ALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLE 129

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503708030  87 DAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG3914  130 EALAALRRALALNPDFAE--AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDL 193
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 65-145 1.34e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.32  E-value: 1.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  65 RPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLrqKAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHN 144
Cdd:COG3914  142 NPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNA--EALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSN 219


                 .
gi 503708030 145 Y 145
Cdd:COG3914  220 L 220
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 38-152 1.56e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.32  E-value: 1.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  38 LVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLrqKAWYNLGNLHAT 117
Cdd:COG3914   47 LLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNA--EALFNLGNLLLA 124

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 503708030 118 TGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG3914  125 LGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-152 2.01e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.41  E-value: 2.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  66 PNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNY 145
Cdd:COG0457   39 PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE--ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116


                 ....*..
gi 503708030 146 EVVLRNL 152
Cdd:COG0457  117 GLALLEL 123
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-152 5.99e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.86  E-value: 5.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  66 PNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNY 145
Cdd:COG0457   73 PDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE--ALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNL 150


                 ....*..
gi 503708030 146 EVVLRNL 152
Cdd:COG0457  151 GIALEKL 157
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-152 9.31e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.09  E-value: 9.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  66 PNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLrqKAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNY 145
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDA--EALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82


                 ....*..
gi 503708030 146 EVVLRNL 152
Cdd:COG0457   83 GLALQAL 89
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 106-138 1.15e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 47.44  E-value: 1.15e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 503708030   106 KAWYNLGNLHATTGDRQEALKAYRRALTLDPQD 138
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
106-138 1.31e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 47.03  E-value: 1.31e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 503708030  106 KAWYNLGNLHATTGDRQEALKAYRRALTLDPQD 138
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 73-152 7.60e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 7.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  73 FNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG4783    8 YALAQALLLAGDYDEAEALLEKALELDPDNPE--AFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 38-152 7.97e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 7.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  38 LVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHAT 117
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE--ARLNLGLALLK 84

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 503708030 118 TGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRAL 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 63-145 9.11e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 9.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  63 KERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQAR 142
Cdd:COG4235   11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNAD--ALLDLAEALLAAGDTEEAEELLERALALDPDNPEAL 88


                 ...
gi 503708030 143 HNY 145
Cdd:COG4235   89 YLL 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 16-152 2.34e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 2.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  16 LVATLALPSPVWAAGPLERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSV 95
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 503708030  96 TESNRADlrQKAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG5010   81 LQLDPNN--PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSL 135
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
65-144 3.32e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.60  E-value: 3.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  65 RPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHN 144
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAE--AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 63-152 5.52e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.03  E-value: 5.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  63 KERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQAR 142
Cdd:COG2956  138 KLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR--ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPAL 215

                         90
                 ....*....|
gi 503708030 143 HNYEVVLRNL 152
Cdd:COG2956  216 PRLAELYEKL 225
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 106-137 6.80e-06

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 42.12  E-value: 6.80e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 503708030  106 KAWYNLGNLHATTGDRQEALKAYRRALTLDPQ 137
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_8 pfam13181
Tetratricopeptide repeat;
106-137 9.39e-06

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 42.00  E-value: 9.39e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 503708030  106 KAWYNLGNLHATTGDRQEALKAYRRALTLDPQ 137
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 73-138 1.30e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 42.32  E-value: 1.30e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 503708030   73 FNRADALAKLGRVADAKALFQSVTESNRAD-LRQKAWYNLGNLHATTGDRQEALKAYRRALTLDPQD 138
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESpDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 33-150 4.10e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 4.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  33 ERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLG 112
Cdd:COG2956  142 ENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLP--ALPRLA 219

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 503708030 113 NLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVLR 150
Cdd:COG2956  220 ELYEKLGDPEEALELLRKALELDPSDDLLLALADLLER 257
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 42-138 6.14e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 6.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  42 GREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDR 121
Cdd:COG4783   45 GEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE--AYLRLARAYRALGRP 122

                         90
                 ....*....|....*..
gi 503708030 122 QEALKAYRRALTLDPQD 138
Cdd:COG4783  123 DEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 42-142 6.85e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.92  E-value: 6.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  42 GREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDR 121
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPE--ALYLLGLAAFQQGDY 101

                         90       100
                 ....*....|....*....|.
gi 503708030 122 QEALKAYRRALTLDPQDVQAR 142
Cdd:COG4235  102 AEAIAAWQKLLALLPADAPAR 122
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 63-144 8.93e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.56  E-value: 8.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  63 KERPNDVVLDFNRADALAKLGRVADAKALFQSVTEsnRADLRQKAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQAR 142
Cdd:COG2956   36 ELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLE--RDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEAL 113


                 ..
gi 503708030 143 HN 144
Cdd:COG2956  114 RL 115
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
78-152 9.68e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 9.68e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 503708030  78 ALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALkAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNAD--ALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLEL 72
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 77-141 1.07e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 1.07e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503708030  77 DALAKLGRVADAKALFQSVTESN-RADLRQKAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQA 141
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRYpNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKA 66
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 66-145 1.08e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.18  E-value: 1.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  66 PNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNY 145
Cdd:COG2956   73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE--ALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCEL 150
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 33-142 4.33e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 4.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  33 ERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLG 112
Cdd:COG2956   74 DRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH--AYCELA 151

                         90       100       110
                 ....*....|....*....|....*....|
gi 503708030 113 NLHATTGDRQEALKAYRRALTLDPQDVQAR 142
Cdd:COG2956  152 ELYLEQGDYDEAIEALEKALKLDPDCARAL 181
TPR_12 pfam13424
Tetratricopeptide repeat;
74-137 4.39e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.52  E-value: 4.39e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030   74 NRADALAKLGRVADAKALFQSVTESNRA----DLRQKAW--YNLGNLHATTGDRQEALKAYRRALTLDPQ 137
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALEIARRllgpDHPLTATtlLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 3-136 1.30e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030   3 AAKTRAARWVAWGLVATLALPSPVWAAGPLERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKL 82
Cdd:COG5010   22 TLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS 101

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 503708030  83 GRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDP 136
Cdd:COG5010  102 GDKDEAKEYYEKALALSPDNPN--AYSNLAALLLSLGQDDEAKAALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 28-152 1.37e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 40.36  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  28 AAGPLERDHPLVEQGREAYTAGRFEEALEAFEAAKKERPNDVVLDFNRADALAKLGRVADAKALFQSVTEsnRADLRQKA 107
Cdd:COG3914    3 AAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAA--ALLLLAAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 503708030 108 WYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVLRNL 152
Cdd:COG3914   81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLAL 125
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 73-142 1.52e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 1.52e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 503708030  73 FNRADALAKLGRVADAKALFQSVTESN-RADLRQKAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQAR 142
Cdd:COG1729   34 YWLGEAYYALGDYDEAAEAFEKLLKRYpDSPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPDSEAAK 104
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
63-156 2.39e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.74  E-value: 2.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  63 KERPNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQAR 142
Cdd:COG4785  101 ELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAY--AYLNRGIALYYLGRYELAIADLEKALELDPNDPERA 178

                         90
                 ....*....|....
gi 503708030 143 HNYEVVLRNLPPPQ 156
Cdd:COG4785  179 LWLYLAERKLDPEK 192
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 109-149 3.05e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 38.11  E-value: 3.05e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 503708030 109 YNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVVL 149
Cdd:PRK02603  76 YNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIY 116
ycf3 CHL00033
photosystem I assembly protein Ycf3
 108-148 3.06e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 38.06  E-value: 3.06e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 503708030 108 WYNLGNLHATTGDRQEALKAYRRALTLDPQDVQARHNYEVV 148
Cdd:CHL00033  75 LYNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVI 115
RPN7 pfam10602
26S proteasome subunit RPN7; RPN7 (known as the non ATPase regulatory subunit 6 in higher ...
 97-132 4.92e-03

26S proteasome subunit RPN7; RPN7 (known as the non ATPase regulatory subunit 6 in higher eukaryotes) is one of the lid subunits of the 26S proteasome and has been shown in Saccharomyces cerevisiae to be required for structural integrity. The 26S proteasome is is involved in the ATP-dependent degradation of ubiquitinated proteins.


Pssm-ID: 431387  Cd Length: 174  Bit Score: 37.17  E-value: 4.92e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 503708030   97 ESNRADL-RQKAWYNLGNLHATTGDRQEALKAYRRAL 132
Cdd:pfam10602  27 KENLGKEeIRMANLDLAEHYAKIGDLENALKAYERAR 63
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
66-144 4.95e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.97  E-value: 4.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503708030  66 PNDVVLDFNRADALAKLGRVADAKALFQSVTESNRADLRQ----KAWYNLGNLHATTGDRQEALKAYRRALTLDPQDVQA 141
Cdd:COG4785   30 LFAAVLALAIALADLALALAAAALAAAALAAERIDRALALpdlaQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEA 109


                 ...
gi 503708030 142 RHN 144
Cdd:COG4785  110 YNN 112
TPR_7 pfam13176
Tetratricopeptide repeat;
107-138 8.08e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 33.67  E-value: 8.08e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 503708030  107 AWYNLGNLHATTGDRQEALKAYRRALTLDPQD 138
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDP 32
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 74-136 8.18e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 37.61  E-value: 8.18e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503708030  74 NRADALAKLGRVADAKALFQSVTESNRADLRqkAWYNLGNLHATTGDRQEALKAYRRALTLDP 136
Cdd:cd24142    5 EKAEELLDQGNFELALKFLQRALELEPNNVE--ALELLGEILLELGDVEEAREVLLRAIELDP 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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