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Conserved domains on  [gi|503992698|ref|WP_014226692|]
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MULTISPECIES: amino acid permease [Klebsiella]

Protein Classification

amino acid permease( domain architecture ID 11435282)

amino acid permease similar to Schizosaccharomyces pombe vacuolar amino acid transporter 5 that is involved in the vacuolar uptake of histidine, glutamate, tyrosine, arginine, lysine, and serine, and required for sporulation

Gene Ontology:  GO:0006865

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
1-409 4.46e-87

Amino acid permease [Amino acid transport and metabolism];


:

Pssm-ID: 440576  Cd Length: 401  Bit Score: 270.09  E-value: 4.46e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698   1 MSKIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiaPGAGITGAVNHY 80
Cdd:COG0814    4 KAMKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSSP--PGADITTVVEEY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698  81 YGKKIGSLITGLYFLAFFVVVLIYAVAITNSLAEQLSRHVPITSQvRALLSLGVVLVLNLIFLMGRHVTIKVMGFLVFPL 160
Cdd:COG0814   82 LGKGGGILIGLLYFFLLYPLLLAYISGGGNILASFLVNQLGLTIP-RWLLSLIFILVLGAIVWLGTRLVDRVNRILVFPK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 161 IACFLFLSIYLMGSWQPAYLTSQMQltPHTFHQIWISIPVMVFAFSHTPIISTFAIDQQEKygeqaMGKCKKIMKVAYTL 240
Cdd:COG0814  161 IIAFLLLSLYLIPHWNLANLLNSAL--PSYLKYLWLALPVLLTSFGFHPIIPSLVKYYRKD-----AKKLRRAILIGSLI 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 241 ICASVLFFVFSCLLSIPAGYIETARHQGVTILSALSMMPGSPaWLAITGIIVAVVAMSKSFLGTYFGVIEGASEIVKtsl 320
Cdd:COG0814  234 PLVIYLFWVFSCLGSLPPEEFAEAKAQNISLLSALANVFNSP-LISYLGPLFAFFAIATSFLGVYLGLFDFLADLFK--- 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 321 aqagiRKSRAFNRAMSILLVSTLTFVVCFINPNAISMIYAVSGPLIAMILFIMPTLSTYLIPALKP--YRSVGS----FI 394
Cdd:COG0814  310 -----KKKSKKGRLKTALLTFLPPWIVALLNPSIFILALGYAGPIIAILLFILPALLVWKVRARFPlkYRVPGGklslIF 384

                        410
                 ....*....|....*
gi 503992698 395 TLVVGLLCVSVMFFS 409
Cdd:COG0814  385 VILFGLLAISAQILS 399
 
Name Accession Description Interval E-value
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
1-409 4.46e-87

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440576  Cd Length: 401  Bit Score: 270.09  E-value: 4.46e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698   1 MSKIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiaPGAGITGAVNHY 80
Cdd:COG0814    4 KAMKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSSP--PGADITTVVEEY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698  81 YGKKIGSLITGLYFLAFFVVVLIYAVAITNSLAEQLSRHVPITSQvRALLSLGVVLVLNLIFLMGRHVTIKVMGFLVFPL 160
Cdd:COG0814   82 LGKGGGILIGLLYFFLLYPLLLAYISGGGNILASFLVNQLGLTIP-RWLLSLIFILVLGAIVWLGTRLVDRVNRILVFPK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 161 IACFLFLSIYLMGSWQPAYLTSQMQltPHTFHQIWISIPVMVFAFSHTPIISTFAIDQQEKygeqaMGKCKKIMKVAYTL 240
Cdd:COG0814  161 IIAFLLLSLYLIPHWNLANLLNSAL--PSYLKYLWLALPVLLTSFGFHPIIPSLVKYYRKD-----AKKLRRAILIGSLI 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 241 ICASVLFFVFSCLLSIPAGYIETARHQGVTILSALSMMPGSPaWLAITGIIVAVVAMSKSFLGTYFGVIEGASEIVKtsl 320
Cdd:COG0814  234 PLVIYLFWVFSCLGSLPPEEFAEAKAQNISLLSALANVFNSP-LISYLGPLFAFFAIATSFLGVYLGLFDFLADLFK--- 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 321 aqagiRKSRAFNRAMSILLVSTLTFVVCFINPNAISMIYAVSGPLIAMILFIMPTLSTYLIPALKP--YRSVGS----FI 394
Cdd:COG0814  310 -----KKKSKKGRLKTALLTFLPPWIVALLNPSIFILALGYAGPIIAILLFILPALLVWKVRARFPlkYRVPGGklslIF 384

                        410
                 ....*....|....*
gi 503992698 395 TLVVGLLCVSVMFFS 409
Cdd:COG0814  385 VILFGLLAISAQILS 399
PRK13629 PRK13629
threonine/serine transporter TdcC; Provisional
 5-403 1.14e-59

threonine/serine transporter TdcC; Provisional


Pssm-ID: 184191  Cd Length: 443  Bit Score: 200.46  E-value: 1.14e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698   5 WSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiAPGAGITGAVNHYYGKK 84
Cdd:PRK13629  17 WRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGS-NPSGNITETVEEHFGKT 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698  85 IGSLITGLYFLAFFVVVLIYAVAITNSLAEQLSRHVPITSQVRALLSLGVVLVLNLIFLMGRHVTIKVMGFLVFPLIACF 164
Cdd:PRK13629  96 GGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASL 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 165 LFLSIYLMGSWQPAYLT----SQMQLTPH--TFHQIWISIPVMVFAFSHTPIISTFAIDQQEKYgEQAMG------KCKK 232
Cdd:PRK13629 176 VLISLSLIPYWNSAVIDqvdlGSLSLTGHdgILVTVWLGISIMVFSFNFSPIVSSFVVSKREEY-EKDFGrdfterKCSQ 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 233 IMKVAYTLICASVLFFVFSCLLSIPAGYIETARHQGVTILSAL----SMMPGSPAWLAIT----GIIVAVVAMSKSFLGT 304
Cdd:PRK13629 255 IISRASMLMVAVVMFFAFSCLFTLSPQNMAEAKAQNIPVLSYLanhfASMTGTKSTFAITleyaASIIALVAIFKSFFGH 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 305 YFGVIEGASEIVkTSLAQAGIRKSRAFNR--AMSILLVSTLTFVVCFINPNAISMIYAVSGPLIAMILFIMPTLSTYLIP 382
Cdd:PRK13629 335 YLGTLEGLNGLI-LKFGYKGDKTKVSLGKlnTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAP 413

                        410       420
                 ....*....|....*....|..
gi 503992698 383 ALKPYRS-VGSFITLVVGLLCV 403
Cdd:PRK13629 414 SLAKYRGrLDNVFVTVIGLLTI 435
 
Name Accession Description Interval E-value
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
1-409 4.46e-87

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440576  Cd Length: 401  Bit Score: 270.09  E-value: 4.46e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698   1 MSKIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiaPGAGITGAVNHY 80
Cdd:COG0814    4 KAMKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSSP--PGADITTVVEEY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698  81 YGKKIGSLITGLYFLAFFVVVLIYAVAITNSLAEQLSRHVPITSQvRALLSLGVVLVLNLIFLMGRHVTIKVMGFLVFPL 160
Cdd:COG0814   82 LGKGGGILIGLLYFFLLYPLLLAYISGGGNILASFLVNQLGLTIP-RWLLSLIFILVLGAIVWLGTRLVDRVNRILVFPK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 161 IACFLFLSIYLMGSWQPAYLTSQMQltPHTFHQIWISIPVMVFAFSHTPIISTFAIDQQEKygeqaMGKCKKIMKVAYTL 240
Cdd:COG0814  161 IIAFLLLSLYLIPHWNLANLLNSAL--PSYLKYLWLALPVLLTSFGFHPIIPSLVKYYRKD-----AKKLRRAILIGSLI 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 241 ICASVLFFVFSCLLSIPAGYIETARHQGVTILSALSMMPGSPaWLAITGIIVAVVAMSKSFLGTYFGVIEGASEIVKtsl 320
Cdd:COG0814  234 PLVIYLFWVFSCLGSLPPEEFAEAKAQNISLLSALANVFNSP-LISYLGPLFAFFAIATSFLGVYLGLFDFLADLFK--- 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 321 aqagiRKSRAFNRAMSILLVSTLTFVVCFINPNAISMIYAVSGPLIAMILFIMPTLSTYLIPALKP--YRSVGS----FI 394
Cdd:COG0814  310 -----KKKSKKGRLKTALLTFLPPWIVALLNPSIFILALGYAGPIIAILLFILPALLVWKVRARFPlkYRVPGGklslIF 384

                        410
                 ....*....|....*
gi 503992698 395 TLVVGLLCVSVMFFS 409
Cdd:COG0814  385 VILFGLLAISAQILS 399
PRK13629 PRK13629
threonine/serine transporter TdcC; Provisional
 5-403 1.14e-59

threonine/serine transporter TdcC; Provisional


Pssm-ID: 184191  Cd Length: 443  Bit Score: 200.46  E-value: 1.14e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698   5 WSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiAPGAGITGAVNHYYGKK 84
Cdd:PRK13629  17 WRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGS-NPSGNITETVEEHFGKT 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698  85 IGSLITGLYFLAFFVVVLIYAVAITNSLAEQLSRHVPITSQVRALLSLGVVLVLNLIFLMGRHVTIKVMGFLVFPLIACF 164
Cdd:PRK13629  96 GGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASL 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 165 LFLSIYLMGSWQPAYLT----SQMQLTPH--TFHQIWISIPVMVFAFSHTPIISTFAIDQQEKYgEQAMG------KCKK 232
Cdd:PRK13629 176 VLISLSLIPYWNSAVIDqvdlGSLSLTGHdgILVTVWLGISIMVFSFNFSPIVSSFVVSKREEY-EKDFGrdfterKCSQ 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 233 IMKVAYTLICASVLFFVFSCLLSIPAGYIETARHQGVTILSAL----SMMPGSPAWLAIT----GIIVAVVAMSKSFLGT 304
Cdd:PRK13629 255 IISRASMLMVAVVMFFAFSCLFTLSPQNMAEAKAQNIPVLSYLanhfASMTGTKSTFAITleyaASIIALVAIFKSFFGH 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503992698 305 YFGVIEGASEIVkTSLAQAGIRKSRAFNR--AMSILLVSTLTFVVCFINPNAISMIYAVSGPLIAMILFIMPTLSTYLIP 382
Cdd:PRK13629 335 YLGTLEGLNGLI-LKFGYKGDKTKVSLGKlnTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAP 413

                        410       420
                 ....*....|....*....|..
gi 503992698 383 ALKPYRS-VGSFITLVVGLLCV 403
Cdd:PRK13629 414 SLAKYRGrLDNVFVTVIGLLTI 435
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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