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Conserved domains on  [gi|503993432|ref|WP_014227426|]
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MULTISPECIES: 1,4-dihydroxy-2-naphthoate polyprenyltransferase [Klebsiella]

Protein Classification

prenyltransferase( domain architecture ID 10794674)

prenyltransferase transfers an isoprenyl group to an aromatic substrate acceptor; may be involved in the biosynthesis of menaquinone or phylloquinone

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
menA TIGR00751
1,4-dihydroxy-2-naphthoate octaprenyltransferase; This membrane-associated enzyme converts 1, ...
 17-300 1.55e-147

1,4-dihydroxy-2-naphthoate octaprenyltransferase; This membrane-associated enzyme converts 1,4-dihydroxy-2-naphthoic acid (DHNA) to demethylmenaquinone, a step in menaquinone biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


:

Pssm-ID: 129834  Cd Length: 284  Bit Score: 415.82  E-value: 1.55e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   17 RPKTLPLAFAAIIVGSALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGAITQAQMK 96
Cdd:TIGR00751   1 RPKTLPLAIAPIVAGTALAAWLHAFVWLVALLALATAVLLQILSNYANDYGDGIKGSDTDDRIGPLRGVQKGLITPREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   97 RALILTVALICLSGLALLFLAWQTMADFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVGSWYLQAH 176
Cdd:TIGR00751  81 TALITSVALGALSGLVLALLAAPNLSDLFWFIALGALCIAAAITYTVGSKPYGYAGLGDISVLVFFGPLAVLGTQYLQAH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  177 SVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLHNPWGWLF 256
Cdd:TIGR00751 161 RVDWVGILPAVATGLLACAVLNINNLRDIPTDARAGKNTLAVRLGDARTRMYHQGLLAVAGVCTFVFMLATPISWWCVLF 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 503993432  257 LLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIG 300
Cdd:TIGR00751 241 LLAAPLLLKAAGPVRSGRGPRELRPVLRDTGLAMLLWNLLFALG 284
 
Name Accession Description Interval E-value
menA TIGR00751
1,4-dihydroxy-2-naphthoate octaprenyltransferase; This membrane-associated enzyme converts 1, ...
 17-300 1.55e-147

1,4-dihydroxy-2-naphthoate octaprenyltransferase; This membrane-associated enzyme converts 1,4-dihydroxy-2-naphthoic acid (DHNA) to demethylmenaquinone, a step in menaquinone biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 129834  Cd Length: 284  Bit Score: 415.82  E-value: 1.55e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   17 RPKTLPLAFAAIIVGSALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGAITQAQMK 96
Cdd:TIGR00751   1 RPKTLPLAIAPIVAGTALAAWLHAFVWLVALLALATAVLLQILSNYANDYGDGIKGSDTDDRIGPLRGVQKGLITPREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   97 RALILTVALICLSGLALLFLAWQTMADFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVGSWYLQAH 176
Cdd:TIGR00751  81 TALITSVALGALSGLVLALLAAPNLSDLFWFIALGALCIAAAITYTVGSKPYGYAGLGDISVLVFFGPLAVLGTQYLQAH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  177 SVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLHNPWGWLF 256
Cdd:TIGR00751 161 RVDWVGILPAVATGLLACAVLNINNLRDIPTDARAGKNTLAVRLGDARTRMYHQGLLAVAGVCTFVFMLATPISWWCVLF 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 503993432  257 LLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIG 300
Cdd:TIGR00751 241 LLAAPLLLKAAGPVRSGRGPRELRPVLRDTGLAMLLWNLLFALG 284
PRK06080 PRK06080
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated
 8-302 4.11e-143

1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated


Pssm-ID: 235695  Cd Length: 293  Bit Score: 404.91  E-value: 4.11e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   8 RTQAWLESLRPKTLPLAFAAIIVGSALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQK 87
Cdd:PRK06080   2 TFKAWLELARPKTLPAAFAPVLVGTALAYWLGSFHPLLALLALLAALLLQIATNLANDYGDYVKGTDTEDRVGPLRAIGR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  88 GAITQAQMKRALILTVALICLSGLALLFLAwqtmadFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSV 167
Cdd:PRK06080  82 GGISPKQVKRAAIAFFGLAALLGLYLVAVS------GWWLLLLGLLCIAAAILYTGGPKPYGYTGLGELFVGVFFGLVIV 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 168 VGSWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLS 247
Cdd:PRK06080 156 LGTYYLQAGTVDSAVFLPALPCGLLIGAVLLANNIRDIETDRENGKNTLAVRLGDKNARRLHAALLALAYLCIVLLALLG 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 503993432 248 LHNPWGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIGII 302
Cdd:PRK06080 236 LASPWGLLFLLSLPLAVKAARPVLRKQKPETLIPALKATGKTNLLFGLLFAIGLL 290
MenA COG1575
1,4-dihydroxy-2-naphthoate polyprenyltransferase [Coenzyme transport and metabolism]; 1, ...
 11-305 3.07e-110

1,4-dihydroxy-2-naphthoate polyprenyltransferase [Coenzyme transport and metabolism]; 1,4-dihydroxy-2-naphthoate polyprenyltransferase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 441183  Cd Length: 290  Bit Score: 321.32  E-value: 3.07e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  11 AWLESLRPKTLPLAFAAIIVGSALAWHQ-GSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGA 89
Cdd:COG1575    1 AWLEAARPRTLPAAVAPVLLGTALAYYEtGSFNWLLFLLALLAALLLQIGVNLANDYFDYKKGTDTEERVGPSRVIVSGL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  90 ITQAQMKRALILTVALICLSGLALLFLAwqtmadFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVG 169
Cdd:COG1575   81 LSPKQVLRAALLLLALALLLGLYLVLLS------GWPLLLLGLLGILAAIFYTGGPFPLGYRGLGELFVFLFFGLVAVLG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 170 SWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLH 249
Cdd:COG1575  155 TYYVQTGTLSWAALLASLPVGLLSAAVLLANNLRDIETDRAAGKRTLAVRLGRKRARRLYAALLLLAYLLILLLVLLGLL 234

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 503993432 250 NPWGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIGIICSR 305
Cdd:COG1575  235 PPWALLALLSLPLALKLVRRVLRGAKPEALIPALKNTALLNLLFGLLLALGLLLGR 290
PT_UbiA_UBIAD1 cd13962
1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the ...
 13-300 2.62e-88

1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the synthesis of MK-4. Menaquinones (MKs, also called bacterial forms) are one of the two forms of natural vitamin K, the other being the plant form, phylloquinone (PK). All forms of vitamin K have a 2-methyl-1,4-naphthoquinone (menadione; K3) ring structure in common. At the 3-position of the ring, PK has a phytyl side chain while MKs have several repeating prenyl units. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260125  Cd Length: 283  Bit Score: 265.15  E-value: 2.62e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  13 LESLRPKTLPLAFAAIIVGSALAWHQG-SFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGAIT 91
Cdd:cd13962    1 LLAARPRTLPASLAPVLLGTALAYYLGgFFNWLLFLLALLAALLLQIGVNLANDYFDYKKGTDTEPRSGPSRVLVSGLLS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  92 QAQMKRALILTVALICLSGLALLFLAwqtmadFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVGSW 171
Cdd:cd13962   81 PRQVLRAALVLLLLAALLGLYLVALG------GWLLLLLGLLGILAGYFYTGGPFPLSYRGLGELFVFLFFGLLAVLGTY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 172 YLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLHNP 251
Cdd:cd13962  155 YVQTGSLSWEVLLAALPLGLLIAAILLANNIRDIEADRAAGKRTLAVRLGRKRARRLYAALLLLAYLLLLLLVLLGLLPL 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 503993432 252 WGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIG 300
Cdd:cd13962  235 WSLLALLSLPLAIKLLRRLLRKADKPLLLIALKLTALLTLLFGLLLALG 283
UbiA pfam01040
UbiA prenyltransferase family;
24-278 3.42e-26

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 103.85  E-value: 3.42e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   24 AFAAIIVGSALAWHqGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPdrIGPLRGMQKGAITQAQmkrALILTV 103
Cdd:pfam01040   1 LLIPALAGLALAAG-GVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMP--RTPNRPLPSGRISPRE---ALIFAL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  104 ALICLSGLALLFLAWQTMadfigfmVLGGLSIVAAITYTVGTRPYGYigLGDISVLVFFGWLSVVGsWYLQAHSVEAVIF 183
Cdd:pfam01040  75 VLLALGLLLLLLLNPLTA-------LLGLAALLLYVLYTLRLKRRTL--LGQLVGGLAFGLPPLLG-WAAVTGSLSPLAL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  184 LPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLHNPWGWLFLLATPLL 263
Cdd:pfam01040 145 LLALALFLWTWAIALANDLRDREDDRKAGIKTLPVVLGRKAARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALA 224

                         250
                  ....*....|....*
gi 503993432  264 VKQARYVMRERDPVA 278
Cdd:pfam01040 225 LLYAARLLRLRDPKK 239
 
Name Accession Description Interval E-value
menA TIGR00751
1,4-dihydroxy-2-naphthoate octaprenyltransferase; This membrane-associated enzyme converts 1, ...
 17-300 1.55e-147

1,4-dihydroxy-2-naphthoate octaprenyltransferase; This membrane-associated enzyme converts 1,4-dihydroxy-2-naphthoic acid (DHNA) to demethylmenaquinone, a step in menaquinone biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 129834  Cd Length: 284  Bit Score: 415.82  E-value: 1.55e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   17 RPKTLPLAFAAIIVGSALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGAITQAQMK 96
Cdd:TIGR00751   1 RPKTLPLAIAPIVAGTALAAWLHAFVWLVALLALATAVLLQILSNYANDYGDGIKGSDTDDRIGPLRGVQKGLITPREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   97 RALILTVALICLSGLALLFLAWQTMADFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVGSWYLQAH 176
Cdd:TIGR00751  81 TALITSVALGALSGLVLALLAAPNLSDLFWFIALGALCIAAAITYTVGSKPYGYAGLGDISVLVFFGPLAVLGTQYLQAH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  177 SVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLHNPWGWLF 256
Cdd:TIGR00751 161 RVDWVGILPAVATGLLACAVLNINNLRDIPTDARAGKNTLAVRLGDARTRMYHQGLLAVAGVCTFVFMLATPISWWCVLF 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 503993432  257 LLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIG 300
Cdd:TIGR00751 241 LLAAPLLLKAAGPVRSGRGPRELRPVLRDTGLAMLLWNLLFALG 284
PRK06080 PRK06080
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated
 8-302 4.11e-143

1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated


Pssm-ID: 235695  Cd Length: 293  Bit Score: 404.91  E-value: 4.11e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   8 RTQAWLESLRPKTLPLAFAAIIVGSALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQK 87
Cdd:PRK06080   2 TFKAWLELARPKTLPAAFAPVLVGTALAYWLGSFHPLLALLALLAALLLQIATNLANDYGDYVKGTDTEDRVGPLRAIGR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  88 GAITQAQMKRALILTVALICLSGLALLFLAwqtmadFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSV 167
Cdd:PRK06080  82 GGISPKQVKRAAIAFFGLAALLGLYLVAVS------GWWLLLLGLLCIAAAILYTGGPKPYGYTGLGELFVGVFFGLVIV 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 168 VGSWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLS 247
Cdd:PRK06080 156 LGTYYLQAGTVDSAVFLPALPCGLLIGAVLLANNIRDIETDRENGKNTLAVRLGDKNARRLHAALLALAYLCIVLLALLG 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 503993432 248 LHNPWGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIGII 302
Cdd:PRK06080 236 LASPWGLLFLLSLPLAVKAARPVLRKQKPETLIPALKATGKTNLLFGLLFAIGLL 290
MenA COG1575
1,4-dihydroxy-2-naphthoate polyprenyltransferase [Coenzyme transport and metabolism]; 1, ...
 11-305 3.07e-110

1,4-dihydroxy-2-naphthoate polyprenyltransferase [Coenzyme transport and metabolism]; 1,4-dihydroxy-2-naphthoate polyprenyltransferase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 441183  Cd Length: 290  Bit Score: 321.32  E-value: 3.07e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  11 AWLESLRPKTLPLAFAAIIVGSALAWHQ-GSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGA 89
Cdd:COG1575    1 AWLEAARPRTLPAAVAPVLLGTALAYYEtGSFNWLLFLLALLAALLLQIGVNLANDYFDYKKGTDTEERVGPSRVIVSGL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  90 ITQAQMKRALILTVALICLSGLALLFLAwqtmadFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVG 169
Cdd:COG1575   81 LSPKQVLRAALLLLALALLLGLYLVLLS------GWPLLLLGLLGILAAIFYTGGPFPLGYRGLGELFVFLFFGLVAVLG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 170 SWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLH 249
Cdd:COG1575  155 TYYVQTGTLSWAALLASLPVGLLSAAVLLANNLRDIETDRAAGKRTLAVRLGRKRARRLYAALLLLAYLLILLLVLLGLL 234

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 503993432 250 NPWGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIGIICSR 305
Cdd:COG1575  235 PPWALLALLSLPLALKLVRRVLRGAKPEALIPALKNTALLNLLFGLLLALGLLLGR 290
PT_UbiA_UBIAD1 cd13962
1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the ...
 13-300 2.62e-88

1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the synthesis of MK-4. Menaquinones (MKs, also called bacterial forms) are one of the two forms of natural vitamin K, the other being the plant form, phylloquinone (PK). All forms of vitamin K have a 2-methyl-1,4-naphthoquinone (menadione; K3) ring structure in common. At the 3-position of the ring, PK has a phytyl side chain while MKs have several repeating prenyl units. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260125  Cd Length: 283  Bit Score: 265.15  E-value: 2.62e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  13 LESLRPKTLPLAFAAIIVGSALAWHQG-SFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGAIT 91
Cdd:cd13962    1 LLAARPRTLPASLAPVLLGTALAYYLGgFFNWLLFLLALLAALLLQIGVNLANDYFDYKKGTDTEPRSGPSRVLVSGLLS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  92 QAQMKRALILTVALICLSGLALLFLAwqtmadFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVGSW 171
Cdd:cd13962   81 PRQVLRAALVLLLLAALLGLYLVALG------GWLLLLLGLLGILAGYFYTGGPFPLSYRGLGELFVFLFFGLLAVLGTY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 172 YLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLHNP 251
Cdd:cd13962  155 YVQTGSLSWEVLLAALPLGLLIAAILLANNIRDIEADRAAGKRTLAVRLGRKRARRLYAALLLLAYLLLLLLVLLGLLPL 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 503993432 252 WGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIG 300
Cdd:cd13962  235 WSLLALLSLPLAIKLLRRLLRKADKPLLLIALKLTALLTLLFGLLLALG 283
UbiA pfam01040
UbiA prenyltransferase family;
24-278 3.42e-26

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 103.85  E-value: 3.42e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   24 AFAAIIVGSALAWHqGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPdrIGPLRGMQKGAITQAQmkrALILTV 103
Cdd:pfam01040   1 LLIPALAGLALAAG-GVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMP--RTPNRPLPSGRISPRE---ALIFAL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  104 ALICLSGLALLFLAWQTMadfigfmVLGGLSIVAAITYTVGTRPYGYigLGDISVLVFFGWLSVVGsWYLQAHSVEAVIF 183
Cdd:pfam01040  75 VLLALGLLLLLLLNPLTA-------LLGLAALLLYVLYTLRLKRRTL--LGQLVGGLAFGLPPLLG-WAAVTGSLSPLAL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  184 LPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSLHNPWGWLFLLATPLL 263
Cdd:pfam01040 145 LLALALFLWTWAIALANDLRDREDDRKAGIKTLPVVLGRKAARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALA 224

                         250
                  ....*....|....*
gi 503993432  264 VKQARYVMRERDPVA 278
Cdd:pfam01040 225 LLYAARLLRLRDPKK 239
PRK07419 PRK07419
2-carboxy-1,4-naphthoquinone phytyltransferase;
1-270 2.56e-17

2-carboxy-1,4-naphthoquinone phytyltransferase;


Pssm-ID: 236015  Cd Length: 304  Bit Score: 80.34  E-value: 2.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   1 MTEHAITRTQAWLESLRPKTLPLAFAAIIVGSALAWHQ-GSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSD--KPD 77
Cdd:PRK07419   4 TTSMSPSRRKLWLAAIKPPMYSVAIMPILVGTAWALGEtGVFRLDQFITFLLAAILILAWENLSNDVFDADTGIDknKFH 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  78 RIGPLRGmqkgaitqaqmKRALILTVALICLS-GLALLF-LAWQTmadfiGFMVLGGLSIVAAITYTVGTRPY--GYIGL 153
Cdd:PRK07419  84 SVVNLTG-----------NKSLVFWLANLFLLlGLLGILaIALQS-----DWTVLGLVLLCCFLGYLYQGPPFrlGYQGL 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 154 GDISVLVFFGWLSVVGSWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLL 233
Cdd:PRK07419 148 GEPLCFLAFGPLAVAAALYSQTPSWSLIPLAASIILGLATSLILFCSHFHQVEDDLAAGKRSPIVRLGTKRGAQLLPWIV 227

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 503993432 234 FGAPLCLALFNLLSLHNPWGWLFLLATPLLVKQARYV 270
Cdd:PRK07419 228 GLIYALELLPVLLGFWPWTTLLSLLSLPFAIKLIRLV 264
PRK13387 PRK13387
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Provisional
 13-308 2.73e-14

1,4-dihydroxy-2-naphthoate octaprenyltransferase; Provisional


Pssm-ID: 237373  Cd Length: 317  Bit Score: 72.13  E-value: 2.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  13 LESLRPKTLPLAFAAIIVGSALAWHQ-GSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIGplrgmQKGAIT 91
Cdd:PRK13387   7 LKLVEIHTKIASFFPVILGTLFSLYVaKIFDWLLFLAFMVAMLAFDIATTAINNYMDFKKALDTADYVG-----IGNGIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  92 QAQMKRALILTVALICLSgLALLFLAWQTMADFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVGSW 171
Cdd:PRK13387  82 QHGLKPRNVLTVILLMYV-VAAILGVYLCMNTSWLLLVIGLICFAIGILYTGGPLPLSRMPLGEIFSGLTMGFGIFLLAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 172 YLQAHS--VEAVIFLPATA------------------CGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHAC 231
Cdd:PRK13387 161 YINTNTitIESLLFQGEMFtiqgnliaiiaigvislpIIFTIANIMLANNLRDLDEDIKNHRYTLVYYIGREKGVVLFAI 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 503993432 232 LLFGAPLCLALFNLLSLHNPWGWLFLLATPLLVKQARYVMRE-RDPVAMRPMLERTVkgalLTNLLFVIGIICSRLVG 308
Cdd:PRK13387 241 LFYASYLAIAVIVLMGYISPWALLSFLTLRKPISNLQSFQKEaKDPKYFVIAIRNTV----LTNTTFGFLLSASLLIQ 314
ubiA PRK05951
prenyltransferase; Reviewed
 17-307 3.48e-14

prenyltransferase; Reviewed


Pssm-ID: 180323  Cd Length: 296  Bit Score: 71.35  E-value: 3.48e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  17 RPKTLPLAFAAIIVGSALA-WHQGSFDPWVALLAIITAGLLQILSNLANDYGDAVKGSDKPDRIG-PLRGMQKGAITQAQ 94
Cdd:PRK05951  12 RPWSFVMTAIVAFFSIAYGyYLFRSFDPLLGALMLLGYFLLHASLNVFNDYKDYVLDCDHHETTGyRQHPIQAGIMTLGH 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  95 MKraliltVALICLSGLALLFLAWQTMADFIGFMVLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFGWLSVVGSWYLQ 174
Cdd:PRK05951  92 LR------VLGIALGAIALQLGWSLVLDRGIGAVTLALLGVFLWTCYMGPPFFLKYRWLGEHLVFYAWSHMLVMGLIYVW 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 175 AHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLfGAPLCLALFNLLSLHNPWGW 254
Cdd:PRK05951 166 LGNLSSPNLLAGVPLGLLMALVLLSNNLRDIEDDERKGIPTLAVIFGRRGAALYIFALL-SPYVILQILLIAILTPLISL 244

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 503993432 255 LFLLATPLLVKQARYVMRERDPVAMrpmlERTVKGALLTNLLFVIGIICSRLV 307
Cdd:PRK05951 245 WALLSLLVAYALCLWQLRKFPPDPD----EATVQLFMLFGYLYILATLLSALG 293
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 10-302 1.90e-13

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 69.10  E-value: 1.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  10 QAWLESLR---PKTLPLAFAAIIVGSALAwHQGSFDPWVALLAIITAGLLQILSNLANDYGDAvkgsdKPDRI---GPLR 83
Cdd:COG0382    1 RAYLRLLRldrPIGILLLLWPTLWALFLA-AGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDR-----EIDRInerKPNR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  84 GMQKGAITQAQmkrALILTVALICLSGLALLFLAWQTMAdfigfmvLGGLSIVAAITYTVGTRPYGYIGLGDISVLVFFG 163
Cdd:COG0382   75 PLASGRISLRE---ALLLAIVLLLLALALALLLNPLTFL-------LALAALALAWAYSLFLKRFTLLGNLVLGLLFGLG 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 164 WLsvvGSWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALF 243
Cdd:COG0382  145 IL---MGFAAVTGSLPLSAWLLALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALIIAGVLYALAVLLLLLL 221

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 503993432 244 NLLSLHNPWGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIGII 302
Cdd:COG0382  222 GLLAGLGLLYLLGLLAALLLLYLSQLWLLRPRKKDPARALKLFKLNMLLGLLLFLGIAL 280
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 13-292 2.01e-13

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 68.91  E-value: 2.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  13 LESLRPKTLPLAFAAIIVGSALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGD----AVKGSDKPDRIGPLRgmqkg 88
Cdd:cd13956    1 LRLMRPYTLLYVLAPALAGAALAGAFAGPLPALLLLALLAVFLGAGAGYALNDYTDreldAINKPDRPLPSGRLS----- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  89 aitqaqMKRALILTVALICLSGLALLFLAWQTMAdfigfmvLGGLSIVAAITYTVGTRPYGYIGLGDISVLvfFGWLSVV 168
Cdd:cd13956   76 ------PRQALAFAAALLLVGLALALALGPLALL-------LLLAGLLLGLAYSLGLKRLKLGGWGVLGYA--TGLALLP 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 169 GSWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSL 248
Cdd:cd13956  141 GLGAVAAGGLVPLALLLALVFLLLGLGINLYNDLPDVEGDRAAGIRTLPVRLGPRRARRLAAGLLLAALILVVLLAVAGL 220

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 503993432 249 HNPWGWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALL 292
Cdd:cd13956  221 LGPLALLALLAVALLALRARFARADRLPALPRGFLLLAVYRLLL 264
ubiA PRK12884
prenyltransferase; Reviewed
 7-302 1.06e-05

prenyltransferase; Reviewed


Pssm-ID: 183812  Cd Length: 279  Bit Score: 46.10  E-value: 1.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   7 TRTQAWLESLRPKTLPLAFAAIIVGSALAwhQGSFDPWVALLAIITAGLLQILSNLANDYGDAvkgsdKPDRIG-PLRGM 85
Cdd:PRK12884   2 TKMKAYLELLRPEHGLMAGIAVVLGAIIA--LGGLPLDEALLGFLTAFFASGSANALNDYFDY-----EVDRINrPDRPI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  86 QKGAITqaqMKRALILTVALICLSGLALLFLAWQTMADFIgfmvlggLSIVAAITYTVGTRPYGYIGLGDISVLVFFgwl 165
Cdd:PRK12884  75 PSGRIS---RREALLLAILLFILGLIAAYLISPLAFLVVI-------LVSVLGILYNWKLKEYGLIGNLYVAFLTGM--- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 166 SVVGSWYLQAHSVEAVIFLPATAcgLLATAVLNI-NNLRDIDSDRENGKNTLAVRLGPVNARRYH------ACLLFGAPL 238
Cdd:PRK12884 142 TFIFGGIAVGELNEAVILLAAMA--FLMTLGREImKDIEDVEGDRLRGARTLAILYGEKIAGRIAaalfilAVLLSPLPY 219

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 503993432 239 CLALFNLLSLhnpwgWLFLLATPLLVKQARYVMRERDPVAMRPMLERTVKGALLTNLLFVIGII 302
Cdd:PRK12884 220 LFGIFNILYL-----APVLVADLIFLYSAYSLLRSQDRETIRKVRKITLTAMLLALVAFALGAI 278
PLN02922 PLN02922
prenyltransferase
 2-221 5.64e-05

prenyltransferase


Pssm-ID: 215499  Cd Length: 315  Bit Score: 43.96  E-value: 5.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432   2 TEHAITRTQAWLESLRPKTLPLAFAAIIVGSALAWHQ-GSFDP--WVALLAiiTAGLLQILSNLANDYGDAVKGSD--KP 76
Cdd:PLN02922   8 DGEELSRATLWWRAIKLPMYSVALVPLTVGAAAAYLQtGLFDArrYGTLLL--SSVLVITWLNLSNDAYDADTGVDknKK 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  77 DRIGPLRGMQKGaitqaqmkralILTVALICL-SGLALLFLAWQTMADfIGFMVLGGLSIVAAITYTVGTRPYGYIGLGD 155
Cdd:PLN02922  86 ESVVNLVGSRRG-----------VLAAAIGCLaLGAAGLVWASLVAGN-IRVILLLAAAILCGYVYQCPPFRLSYKGLGE 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 503993432 156 ISVLVFFGWLSVVGSWYLQAHSV--EAVIFLPATA--------CGLLATAVLNINNLRDIDSDRENGKNTLAVRLG 221
Cdd:PLN02922 154 PLCFAAFGPLATTAFYLALASGAggSEMAILPLTPtvlsasvlVGLTTTLILFCSHFHQIDGDRAVGKMSPLVRLG 229
PT_UbiA_DGGGPS cd13961
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ...
 11-264 9.70e-05

Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260124  Cd Length: 270  Bit Score: 43.26  E-value: 9.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  11 AWLESLRPKTLPLAFAAIIVGS-ALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGDAvkgsdKPDRI-GPLRGMQKG 88
Cdd:cd13961    1 AYLELIRPPNLLMAALAQYLGAlFALGPLLSLNDLELLLLFLSVFLIAAAGYIINDYFDV-----EIDRInKPDRPIPSG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  89 AITQaqmKRALILTVALICLSGLALLFLAWQTMADFIgfmvlggLSIVAAITYTVGTRPYGYIGLGDISVLV----FFGW 164
Cdd:cd13961   76 RISR---REALILSILLNALGLILAFLLSPLALLIAL-------LNSLLLWLYSHKLKRTPLIGNLLVALLTglpfLFGG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 165 LSVVGSWYlqahsveaVIFLPAtACGLLATAVLNIN-NLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALF 243
Cdd:cd13961  146 LAAGNLLL--------IILLLA-LFAFLITLGREIVkDIEDVEGDRAEGARTLPIVYGIKKAKKIAALLLLLAILLSPLP 216

                        250       260
                 ....*....|....*....|.
gi 503993432 244 NLLSLHNPWGWLFLLATPLLV 264
Cdd:cd13961  217 YLLGGLGILYLILIIIADLLF 237
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 88-276 1.76e-04

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 42.45  E-value: 1.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  88 GAITqaqMKRALILTVALICLSGLALLFLAWQTMAdfigfmvLGGLSIVAAITYTVGTR----PYGYIGLGdisvlvfFG 163
Cdd:cd13959   75 GAIS---VKEALLFLAVQLLLGLALLLQLNPLTIL-------LSPIALLLVLIYPLMKRftywPQLVLGLA-------FG 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 164 WlSVVGSWYLQAHSVEAVIFLPATACGLLATAVLNINNLRDIDSDRENGKNTLAVRLGpVNARRYHACLLFGAPLCLALF 243
Cdd:cd13959  138 W-GPLMGWAAVTGSLPLPALLLYLAVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFG-DRTKLILALLLHLFVALLLLA 215

                        170       180       190
                 ....*....|....*....|....*....|...
gi 503993432 244 NLLSLHNPWGWLFLLATPLLVKQARYVMRERDP 276
Cdd:cd13959  216 GGLAGLGWPYYLGLGAAAHLLWQEHRLDLPDPL 248
PRK09573 PRK09573
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
 11-225 2.54e-03

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed


Pssm-ID: 181963  Cd Length: 279  Bit Score: 38.79  E-value: 2.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  11 AWLESLRPKTLPLAFAAIIVGsALAWHQGSFDPWVALLAIITAGLLQILSNLANDYGDAvkgsdKPDRIG-PLRGMQKGA 89
Cdd:PRK09573   5 AYFELIRPKNCIGASIGAIIG-YLIASNFKIDLKGIILAALVVFLVCAGGNVINDIYDI-----EIDKINkPERPIPSGR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  90 ITqaqMKRALILTVALICLsGLALLFlawqtmadFIGF--MVLGGLSIVAAITYTVGTRPYGYIGLGDISVLV----FFG 163
Cdd:PRK09573  79 IS---LKEAKIFSITLFIV-GLILSI--------FINIyaFLIALLNSILLYLYAKDLKKTGLIGNLIVAYLTglsfIFG 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 503993432 164 WLSVvgswylqaHSVEAVIFLpaTACGLLATAVLNI-NNLRDIDSDRENGKNTLAVRLGPVNA 225
Cdd:PRK09573 147 GLAV--------FNVLRIIIL--FLCAFFSTWSREIvKDIEDIEGDLKENVITLPIKYGIKKS 199
ubiA PRK12882
prenyltransferase; Reviewed
 11-259 3.51e-03

prenyltransferase; Reviewed


Pssm-ID: 183811  Cd Length: 276  Bit Score: 38.42  E-value: 3.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  11 AWLESLRPKTLPLAFAAIIVGSALAWHQGSFDPWVALLAIITAgLLQILSNLANDYGDAvkgsdKPDRIG-PLRGMQKGA 89
Cdd:PRK12882   6 GYLELTRPVNAVVAGVAAFIGAFIAGGILSSPSLTGLAFAAVF-LATGAGNAINDYFDR-----EIDRINrPDRPIPSGA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  90 ITqaqMKRALILTVALICLSGLALLFLAWQTMAdfigfmvLGGLSIVAAITYTvgTRPYGYIGLGDISVLVFFGWLSVVG 169
Cdd:PRK12882  80 VS---PRGALAFSILLFAAGVALAFLLPPLCLA-------IALFNSLLLVLYA--ETLKGTPGLGNASVAYLTGSTFLFG 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 170 SWYLQAHSVEAVIFLPA-TACGLLATAVlnINNLRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFNLLSL 248
Cdd:PRK12882 148 GAAVGTEGLLALLVLFAlAALATLAREI--IKDVEDIEGDRAEGARTLPILIGVRKALYVAAAFLLVAVAASPLPYLLST 225

                        250
                 ....*....|.
gi 503993432 249 hnpWGWLFLLA 259
Cdd:PRK12882 226 ---FGLWYLVL 233
PT_UbiA_5 cd13967
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 95-258 9.16e-03

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260130  Cd Length: 277  Bit Score: 37.20  E-value: 9.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432  95 MKRALILTVALICLSGLALLFLAWQTMadFIGFMVLGGLsiVAAITYTVGTRP--YGYIGLGDI----SVLVFFGW---L 165
Cdd:cd13967   72 EKYKKLLLALAIAAGLLALALAFILGL--LAFAILLLPL--LLGLLYSLPIKPgkLRLRRRKDIpgskNLVVALAWavvI 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 503993432 166 SVVGSWYLQAHSVE-AVIFLPATACGLLATAVLNInnlRDIDSDRENGKNTLAVRLGPVNARRYHACLLFGAPLCLALFN 244
Cdd:cd13967  148 ALLPALYGQPSTPSvLVVFLFFFLKVFVNTAIFDI---RDVEGDRIVGIETLPVLLGEERTRLLLLVLNILLALLLVAGV 224

                        170
                 ....*....|....
gi 503993432 245 LLSLHNPWGWLFLL 258
Cdd:cd13967  225 LLGLLASEFLVLLL 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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