|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
4-244 |
1.27e-81 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 245.11 E-value: 1.27e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 4 ITSIQNPKIKNYNKLKKKKERDKQGLAILEGFHLIEEAVESQIKVTQLFmIEPSRVP--TELIEAAEE----VYEITQKV 77
Cdd:COG0566 1 MTSPSNPRVKDLRKLRDKKYREEEGLFLAEGRHAVEEALKAGREIEELL-VTEGALDrlAELLALAKAagipVYEVSREV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 78 AETLSGTVTPQGIFAIIEKPQV----DVTAAKQ----VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVL 149
Cdd:COG0566 80 LDKLSGTETHQGVLAVVRPPEYadleDLLAEAGepplLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 150 RASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTALQDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPI 226
Cdd:COG0566 160 RASAGALFHVPVARVTNLADALEELKEagfWVVGTDLDGEASLYEVDLPGPV-ALVLGNEGKGLSRLVLEACDELVRIPM 238
|
250
....*....|....*...
gi 504427111 227 YGQAESLNVAVAAGVLMF 244
Cdd:COG0566 239 AGGVESLNVAVAAAILLY 256
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
107-246 |
2.34e-62 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 191.87 E-value: 2.34e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTAL 183
Cdd:cd18095 2 VLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEagyKVVAADL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504427111 184 QDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYL 246
Cdd:cd18095 82 DGGSSLYDLDLPKPV-ALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
107-244 |
5.23e-44 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 144.98 E-value: 5.23e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTK-GTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTA 182
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEagyAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504427111 183 LqDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMF 244
Cdd:pfam00588 83 L-GGKSLYEIDFPKKV-ALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
29-247 |
3.03e-36 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 128.23 E-value: 3.03e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 29 LAILEGFHLIEEAVESQIKVtQLFMIEPSRVPTELIEAAEE----VYEITQKVAETLSGTVTPQGIFAIIEKPQ------ 98
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQRV-FILKGLESKRLKKLIQLAKKqginIQLVDRQKLDQLTKGGNHQGIAAKVKPILykdlnd 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 99 -VDVTAAKQ---VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSF 174
Cdd:TIGR00186 80 lYKTAKSKKqpfLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504427111 175 K---GPIYGTALQDATTYHQVASqQDTFALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYLK 247
Cdd:TIGR00186 160 KesgFWTVGTDLDAQDTLYQVKL-TKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIK 234
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
88-244 |
1.74e-13 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 67.68 E-value: 1.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 88 QGIFAiiekpqvDVTAAKQ-----------------VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLR 150
Cdd:PRK11181 68 QGIIA-------RVKPGRQlqendlpdllasleqpfLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKK 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 151 ASQGSVFHIPIQYVDDMSAWMSSFKGP---IYGTALQDATTYHQvASQQDTFALILGNEGEGvaMDLLAH-TTQNLI-IP 225
Cdd:PRK11181 141 VACGAAETVPLIRVTNLARTMRMLQEKniwIVGTAGEADHTLYQ-SKLTGPLALVMGAEGEG--MRRLTReHCDELIsIP 217
|
170
....*....|....*....
gi 504427111 226 IYGQAESLNVAVAAGVLMF 244
Cdd:PRK11181 218 MAGSVSSLNVSVATGICLF 236
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
32-96 |
4.50e-11 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 57.16 E-value: 4.50e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 32 LEGFHLIEEAVESQIKVTQLFMIE--PSRVPTELIEAAE---EVYEITQKVAETLSGTVTPQGIFAIIEK 96
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEgrAERLKELLKLAKErgiKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
4-244 |
1.27e-81 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 245.11 E-value: 1.27e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 4 ITSIQNPKIKNYNKLKKKKERDKQGLAILEGFHLIEEAVESQIKVTQLFmIEPSRVP--TELIEAAEE----VYEITQKV 77
Cdd:COG0566 1 MTSPSNPRVKDLRKLRDKKYREEEGLFLAEGRHAVEEALKAGREIEELL-VTEGALDrlAELLALAKAagipVYEVSREV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 78 AETLSGTVTPQGIFAIIEKPQV----DVTAAKQ----VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVL 149
Cdd:COG0566 80 LDKLSGTETHQGVLAVVRPPEYadleDLLAEAGepplLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 150 RASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTALQDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPI 226
Cdd:COG0566 160 RASAGALFHVPVARVTNLADALEELKEagfWVVGTDLDGEASLYEVDLPGPV-ALVLGNEGKGLSRLVLEACDELVRIPM 238
|
250
....*....|....*...
gi 504427111 227 YGQAESLNVAVAAGVLMF 244
Cdd:COG0566 239 AGGVESLNVAVAAAILLY 256
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
107-246 |
2.34e-62 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 191.87 E-value: 2.34e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTAL 183
Cdd:cd18095 2 VLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEagyKVVAADL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504427111 184 QDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYL 246
Cdd:cd18095 82 DGGSSLYDLDLPKPV-ALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
107-244 |
5.23e-44 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 144.98 E-value: 5.23e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTK-GTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTA 182
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEagyAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504427111 183 LqDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMF 244
Cdd:pfam00588 83 L-GGKSLYEIDFPKKV-ALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
107-243 |
1.30e-42 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 141.52 E-value: 1.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMS-SFKGPIYGTALqD 185
Cdd:cd18109 2 TLALDGIQDPGNLGTIIRTADWFGIRQIICSPDTVDPYNPKVVQASMGSIFRVQIHYTDLPALLAElKKAFPVYGADL-D 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 504427111 186 ATTYHQVASQQdTFALILGNEGEGVAMDLLAHTTQNLIIPIYGQ-AESLNVAVAAGVLM 243
Cdd:cd18109 81 GENLYEFTLPE-KGILVMGNEGHGISPEVLKLLTHRLTIPRYGKgAESLNVAVATAILL 138
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
107-246 |
8.85e-38 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 129.04 E-value: 8.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTK-GTADVyQDKVLRASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTA 182
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPKrRSAPL-TPTVAKASAGALEHLPIARVTNLARALEELKEagfWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504427111 183 LQDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYL 246
Cdd:cd18103 81 GEAEKSLYDVDLTGPL-ALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
29-247 |
3.03e-36 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 128.23 E-value: 3.03e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 29 LAILEGFHLIEEAVESQIKVtQLFMIEPSRVPTELIEAAEE----VYEITQKVAETLSGTVTPQGIFAIIEKPQ------ 98
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQRV-FILKGLESKRLKKLIQLAKKqginIQLVDRQKLDQLTKGGNHQGIAAKVKPILykdlnd 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 99 -VDVTAAKQ---VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSF 174
Cdd:TIGR00186 80 lYKTAKSKKqpfLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504427111 175 K---GPIYGTALQDATTYHQVASqQDTFALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYLK 247
Cdd:TIGR00186 160 KesgFWTVGTDLDAQDTLYQVKL-TKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIK 234
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
107-246 |
6.97e-36 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 124.26 E-value: 6.97e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSFK---GPIYGTAL 183
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKeegYPLIGLEL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504427111 184 QDA-TTYHQVASQQDT-FALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYL 246
Cdd:cd18082 81 TDGsIPLSEFKFKKPKkIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
107-244 |
2.64e-35 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 123.07 E-value: 2.64e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYV--DDMSAWMSSFKGPIYGTALQ 184
Cdd:cd18104 2 ILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEAssEETLAWLKENKIRILATTPK 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 185 DATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMF 244
Cdd:cd18104 82 AEKLYYEADLRGPI-AIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLY 140
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
108-244 |
5.32e-29 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 106.57 E-value: 5.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 108 LILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIqyVDDMSaW--MSSFKGPIYGTALQD 185
Cdd:cd18106 3 VICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPI--YGNLS-WddIPNYLPDDSKVFLAD 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504427111 186 ATT----YHQVASQQDTFALILGNEGEGVAMD--LLAHTT--QNLIIPIYGQAESLNVAVAAGVLMF 244
Cdd:cd18106 80 NNLpvqpYDSIDYCSGPIVLVIGGETHGVSPEayKLAHSTggSRVHIPLANGVDSLNSAVAASILLF 146
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
107-244 |
5.06e-26 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 99.00 E-value: 5.06e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVD---DMSAWMSSFK--GP---I 178
Cdd:cd18107 2 VVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRVPsnrELEDWVEARKarGTplqL 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504427111 179 YGTALQDATTYHQVASQQDTFaLILGNEGEGV------AMDLLAHttqnliIPIYGQAESLNVAVAAGVLMF 244
Cdd:cd18107 82 VGTDEHGDHQIADHDFTRPTL-LLIGNETAGLsaawreLCDETVS------IPMAGSASSLNAACAASIFLY 146
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
107-247 |
1.42e-22 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 90.22 E-value: 1.42e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGL-DL-IVMTKGTADVYQdkvlRASQGSVFHIPIQYVDDMSAWMSSFK--GP-IYGT 181
Cdd:cd18092 18 TVVLENVHDPHNASAVLRTCDAFGVqDVhVIEPKNKFKKNR----GVAMGADKWLDVHRHDSTEECLAALKeqGYrIVAT 93
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504427111 182 AL-QDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYLK 247
Cdd:cd18092 94 SLsPDAVPLDELDYTRPT-ALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQ 159
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
107-246 |
7.13e-21 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 85.31 E-value: 7.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLRASQGSVFHIPIQYVDDMSAWMSSFKGP---IYG--T 181
Cdd:cd18097 2 VVVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARgytIIAleT 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504427111 182 AlQDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMFYL 246
Cdd:cd18097 82 T-ENSVPLHEARLPRPL-ALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
107-246 |
2.69e-20 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 84.11 E-value: 2.69e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVM-TKGTAD---VyqdkVLRASQGSVFHIPIQYVDDMS---AWMSSFKGPIY 179
Cdd:cd18105 2 WLLLDEITDPQNLGAILRSAYFLGVDGVVVsSKNSAPlspV----VSKASAGALELMPIYSVDNLAsflKSSKENGWKVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 180 GTAL----------QDATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAE-----SLNVAVAAGVLMF 244
Cdd:cd18105 78 GTSAppsassdkktIPANELSELLLEKPT-ILVLGNEGRGLRTNIKNLCDYLVSIPGGRSAEnpgvdSLNVSVAAGILLH 156
|
..
gi 504427111 245 YL 246
Cdd:cd18105 157 SL 158
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
107-244 |
3.21e-16 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 73.28 E-value: 3.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTA---DAAGLdlIVMTKGTADVYQDKVLRASQGSVFHIPIQYVD--DMSAWMSSFKGPIYGT 181
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSlalGAAGI--VLVDSDLATVADRRLLRASRGYVFSLPVVLADreEAVAFLRDNDIPLMTL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504427111 182 ALQDATTYHQVASQQDTFALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMF 244
Cdd:cd18108 80 DADGDVPVKELGDRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALH 142
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
88-244 |
1.74e-13 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 67.68 E-value: 1.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 88 QGIFAiiekpqvDVTAAKQ-----------------VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKGTADVYQDKVLR 150
Cdd:PRK11181 68 QGIIA-------RVKPGRQlqendlpdllasleqpfLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKK 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 151 ASQGSVFHIPIQYVDDMSAWMSSFKGP---IYGTALQDATTYHQvASQQDTFALILGNEGEGvaMDLLAH-TTQNLI-IP 225
Cdd:PRK11181 141 VACGAAETVPLIRVTNLARTMRMLQEKniwIVGTAGEADHTLYQ-SKLTGPLALVMGAEGEG--MRRLTReHCDELIsIP 217
|
170
....*....|....*....
gi 504427111 226 IYGQAESLNVAVAAGVLMF 244
Cdd:PRK11181 218 MAGSVSSLNVSVATGICLF 236
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
31-98 |
8.63e-13 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 61.87 E-value: 8.63e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504427111 31 ILEGFHLIEEAVESQIKVTQLFMIEPSRVP--TELIEAAEE----VYEITQKVAETLSGTVTPQGIFAIIEKPQ 98
Cdd:pfam08032 1 LIYGRHAVLEALKSGPEIKKLYLTEGRRDPrlKELLKLAKErgikVEEVDRKKLDKLSGTANHQGVVAEVKPYE 74
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
107-244 |
2.20e-11 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 59.92 E-value: 2.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 107 VLILDRIQDPGNLGTMIRTADAAGLDLIVMtkgtadVYQDKV-LRASQGSVFHIPIQYVDDMSAWMSSFKG---PIYGTA 182
Cdd:cd18096 2 YLVLHNVAKRHNIGTIVRSANAFGVKEVHL------VGRRKFnPFGAMGTDRHVKFRHFDTLAEAKEYLKErgiRLVGVE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504427111 183 LQDATTY-HQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQA-ESLNVAVAAGVLMF 244
Cdd:cd18096 76 IVPGAEPiETHPFPGDT-AFVLGNEGTGLSDEQLAICDGFVYIPQYGSGtASLNVSVAASIVLH 138
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
113-244 |
3.06e-11 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 59.47 E-value: 3.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 113 IQDPGNLGTMIRTADAAGLDLIVMtkGTADVYQDKVLRA-SQGSVFHIPIQYV--DDMSAWMSSFKGPIYgTALQDATTY 189
Cdd:cd18091 8 IDKPPNLGGLCRTCEIFGVSKLVL--PNLAVVEDKQFKAlSVSAEKWLPIEEVkpEDLLPYLKEKKQEGY-TIVGLEQTA 84
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 504427111 190 HQVASQQDTF----ALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAAGVLMF 244
Cdd:cd18091 85 NSVSLHDFQFpkktVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIY 143
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
32-96 |
4.50e-11 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 57.16 E-value: 4.50e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 32 LEGFHLIEEAVESQIKVTQLFMIE--PSRVPTELIEAAE---EVYEITQKVAETLSGTVTPQGIFAIIEK 96
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEgrAERLKELLKLAKErgiKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
116-244 |
1.45e-10 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 57.85 E-value: 1.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 116 PGNLGTMIRTADA--AGLDLIvmtKGTADVYQDKVL-RASQGSVFHIPIQYVDDMSAWMSSFK-GPIYGTALQDATTYHQ 191
Cdd:cd18094 10 PQNTGNIARTCAAtgARLHLI---EPLGFSLDDKRLkRAGLDYWDHVDLTVHDSWEAFLEALPpGRLFLFTTKGTKPYTD 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 504427111 192 VASQQDTFaLILGNEGEGVAMDLLAHTTQNLI-IPIYGQAESLNVAVAAGVLMF 244
Cdd:cd18094 87 FDFKPGDY-LVFGRESTGLPEEILDAFPDRRLrIPMRPKVRSLNLSNSVAIVLY 139
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
88-244 |
1.68e-10 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 59.24 E-value: 1.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 88 QGIFAIIEKPQVDVTaakqvLILDRIQDPGNLGTMIRTADAAGLDLIvmtkgtADVYQDKVLR----ASQGSVFHIPIQY 163
Cdd:PRK11081 7 ARICEMLARRQPDLT-----VCMEQVHKPHNVSAIIRTADAVGVHEV------HAVWPGSRMRtmgsTAAGSNSWVQVKT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 164 VDDMSAWMSSFKG---PIYGTALQD-ATTYHQVASQQDTfALILGNEGEGVAMDLLAHTTQNLIIPIYGQAESLNVAVAA 239
Cdd:PRK11081 76 HRTIGDAVAHLKGqgmQILATHLSDtAVDFREIDYTRPT-CILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVAS 154
|
....*
gi 504427111 240 GVLMF 244
Cdd:PRK11081 155 ALILY 159
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
82-243 |
4.17e-09 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 55.94 E-value: 4.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 82 SGTVTPQGI-FAIIEKPQVDV-----TAAKQ--VLILDRIQDPGNLGTMIRTADAAGLDLIVMTKgTADVYQDKVLRASQ 153
Cdd:PRK10864 167 SGTEHHGGVcFLIKKRNGTDVqqwlaQAGAQdcVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQD-AALLESGAAIRTAE 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 154 GSVFHI-PIQyVDDMSAWMSSFKGPIY---------GTALQDATTYHQVAsqqdtfaLILGNEGEGVAMDLLAHTTQNLI 223
Cdd:PRK10864 246 GGAEHVqPIT-GDSFVDVLDDFRQAGYtivttsshkGTPLFKASLPAKMV-------LVLGQEYDGLSDAARQQGDLSVS 317
|
170 180
....*....|....*....|
gi 504427111 224 IPIYGQAESLNVAVAAGVLM 243
Cdd:PRK10864 318 IDGTGNVESLNVSVATGVLL 337
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
116-244 |
5.78e-09 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 53.50 E-value: 5.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 116 PGNLGTMIRTADAAG--LDLI-----VMTkgtadvyqDKVL-RASQGSVFHIPIQYVDDMSAWMSSFKGP-IYGTALQDA 186
Cdd:COG0219 12 PQNTGNIIRLCAATGarLHLIeplgfSLD--------DKKLkRAGLDYWELVDLTVHDSWEAFLEALPGGrLFLFTTKGT 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 504427111 187 TTYHQVASQQDTFaLILGNEGEGVAMDLLA-HTTQNLIIPIYGQAESLNVAVAAGVLMF 244
Cdd:COG0219 84 KPYTDVDYQPGDV-LLFGRETAGLPEEVLAaPADQRLRIPMRPGVRSLNLSNAVAIVLY 141
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
110-244 |
3.80e-05 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 42.25 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427111 110 LDRIQDPGNLGTMIRTADAAGLDLIVMT-------KGTADVyqdkvlrasQGSVFHIPIQYVDDMSawmSSFKGPIYGTA 182
Cdd:cd18098 5 IENPKTPKNVGTLWRAAGCLGASFVFTIgarykrrKQSTDT---------SKAWRHIPLFHYDDLE---DLAEPLPFGAV 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504427111 183 L------QDAT---TYHqvasQQDTFALILGNEGEGVAMDLLAHTTQNLIIPIYGqaeSLNVAVAAGVLMF 244
Cdd:cd18098 73 LvaveltEGATplpDFK----HPDRAVYLLGPEDGGLPQEVLARCHHVVYLPTRG---SLNVAVAGSIVLY 136
|
|
| |
