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Conserved domains on  [gi|504427423|ref|WP_014614525|]
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DMT family transporter [Staphylococcus pseudintermedius]

Protein Classification

DMT family transporter( domain architecture ID 11430850)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others

Gene Ontology:  GO:0016020|GO:0055085|GO:0022857
PubMed:  11432728
TCDB:  2.A.7

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
4-281 4.97e-34

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


:

Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 125.34  E-value: 4.97e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423   4 KVKGILAILISAIGFSFMAVFFRL-SGDLPVFQKSLARNFVAMFIPLFFILKYKQPFFGKLSSQPL-LVTRSVLGL-MGV 80
Cdd:COG0697    1 RLRGILLLLLAALLWGSSFVAIKLaLAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLlLLLRGLLGLaLAF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423  81 LLNIYAIDHMVLSDADILMKLNPFWTILLSLIFLKEFIQKYQITSMVIAIIGMLFVVKPEF---SSDVIPAIVGLLSGVF 157
Cdd:COG0697   81 LLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGgggGGSLLGDLLALLAALS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423 158 AASAYTAVRALSTREAPYTIVFYFSFFSVIVLIPFVAFTFE--PMSLIQIVYLILAGL-SAAVGQIGITVAYSYAPAKDI 234
Cdd:COG0697  161 WALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTGLplPLSAAAWLALLYLGLfGTALAYLLWFRALRRLGASRA 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 504427423 235 SIFTYASIIFTAIIGFILFNESPDFYAIIGYIIILSASYYMFEKARR 281
Cdd:COG0697  241 APLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRERR 287
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
4-281 4.97e-34

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 125.34  E-value: 4.97e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423   4 KVKGILAILISAIGFSFMAVFFRL-SGDLPVFQKSLARNFVAMFIPLFFILKYKQPFFGKLSSQPL-LVTRSVLGL-MGV 80
Cdd:COG0697    1 RLRGILLLLLAALLWGSSFVAIKLaLAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLlLLLRGLLGLaLAF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423  81 LLNIYAIDHMVLSDADILMKLNPFWTILLSLIFLKEFIQKYQITSMVIAIIGMLFVVKPEF---SSDVIPAIVGLLSGVF 157
Cdd:COG0697   81 LLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGgggGGSLLGDLLALLAALS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423 158 AASAYTAVRALSTREAPYTIVFYFSFFSVIVLIPFVAFTFE--PMSLIQIVYLILAGL-SAAVGQIGITVAYSYAPAKDI 234
Cdd:COG0697  161 WALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTGLplPLSAAAWLALLYLGLfGTALAYLLWFRALRRLGASRA 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 504427423 235 SIFTYASIIFTAIIGFILFNESPDFYAIIGYIIILSASYYMFEKARR 281
Cdd:COG0697  241 APLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRERR 287
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
146-276 8.19e-07

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 47.57  E-value: 8.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423  146 IPAIVGLLSGVFAASAYTAVRALSTREAPYTIVFYFSFFSVIVLIPFVAFTFEPMSLIQ---IVYLILAGLSAAVGQIGI 222
Cdd:pfam00892   2 KGILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIAGILLLPFALFTGGKLVIPLkswLALLYLGVLGTFLGFLLY 81
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 504427423  223 TVAYSYAPAKDISIFTYASIIFTAIIGFILFNESPDFYAIIGYIIILSASYYMF 276
Cdd:pfam00892  82 FYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLIL 135
 
Name Accession Description Interval E-value
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
4-281 4.97e-34

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 125.34  E-value: 4.97e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423   4 KVKGILAILISAIGFSFMAVFFRL-SGDLPVFQKSLARNFVAMFIPLFFILKYKQPFFGKLSSQPL-LVTRSVLGL-MGV 80
Cdd:COG0697    1 RLRGILLLLLAALLWGSSFVAIKLaLAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLlLLLRGLLGLaLAF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423  81 LLNIYAIDHMVLSDADILMKLNPFWTILLSLIFLKEFIQKYQITSMVIAIIGMLFVVKPEF---SSDVIPAIVGLLSGVF 157
Cdd:COG0697   81 LLFFLALQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGgggGGSLLGDLLALLAALS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423 158 AASAYTAVRALSTREAPYTIVFYFSFFSVIVLIPFVAFTFE--PMSLIQIVYLILAGL-SAAVGQIGITVAYSYAPAKDI 234
Cdd:COG0697  161 WALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTGLplPLSAAAWLALLYLGLfGTALAYLLWFRALRRLGASRA 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 504427423 235 SIFTYASIIFTAIIGFILFNESPDFYAIIGYIIILSASYYMFEKARR 281
Cdd:COG0697  241 APLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRERR 287
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
146-276 8.19e-07

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 47.57  E-value: 8.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423  146 IPAIVGLLSGVFAASAYTAVRALSTREAPYTIVFYFSFFSVIVLIPFVAFTFEPMSLIQ---IVYLILAGLSAAVGQIGI 222
Cdd:pfam00892   2 KGILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIAGILLLPFALFTGGKLVIPLkswLALLYLGVLGTFLGFLLY 81
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 504427423  223 TVAYSYAPAKDISIFTYASIIFTAIIGFILFNESPDFYAIIGYIIILSASYYMF 276
Cdd:pfam00892  82 FYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLIL 135
RibN COG2510
Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];
149-275 1.61e-06

Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];


Pssm-ID: 442000  Cd Length: 138  Bit Score: 46.72  E-value: 1.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423 149 IVGLLSGVFAASAYTAVRALSTREAPYTIVFYFSFFSVIVLIPFVAFTFEPMSLIQI-----VYLILAGLSAAVGQIGIT 223
Cdd:COG2510    4 LLALLSAFFAGLTAIFAKIGLKGIDPNLATFIRTLVALIFLLLILLVTGKLGELPELspkswLFLLLSGLATGLSWLFYF 83
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 504427423 224 VAYSYAPAKDISIFTYASIIFTAIIGFILFNESPDFYAIIGYIIILSASYYM 275
Cdd:COG2510   84 RALKLGPASIVAPIDKLSPVFTVLLSVLFLGERLTLKQIIGILLIVAGVILL 135
RibN COG2510
Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];
6-137 3.06e-05

Riboflavin transporter RibN, EamA domain [Coenzyme transport and metabolism];


Pssm-ID: 442000  Cd Length: 138  Bit Score: 42.86  E-value: 3.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423   6 KGILAILISAIGFSFMAVFFRL-SGDLPVFQKSLARNFVAM-FIPLFFILKYKQPFFGKLSSQ--PLLVTRSVLGLMGVL 81
Cdd:COG2510    1 SWLLLALLSAFFAGLTAIFAKIgLKGIDPNLATFIRTLVALiFLLLILLVTGKLGELPELSPKswLFLLLSGLATGLSWL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 504427423  82 LNIYAIDHMVLSDADILMKLNPFWTILLSLIFLKEFIQKYQITSMVIAIIGMLFVV 137
Cdd:COG2510   81 FYFRALKLGPASIVAPIDKLSPVFTVLLSVLFLGERLTLKQIIGILLIVAGVILLS 136
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
6-137 3.83e-03

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 36.79  E-value: 3.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504427423    6 KGILAILISAIGFSFMAVFFR-LSGDLPVFQKSLARNFVAMFIPLFFILKYKQPFFGKLSSQPLLVTRSVLG-LMGVLLN 83
Cdd:pfam00892   2 KGILLALLAALIWAIYFVFSKiLLRRISPLTLTFWRFLIAGILLLPFALFTGGKLVIPLKSWLALLYLGVLGtFLGFLLY 81
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 504427423   84 IYAIDHMVLSDADILMKLNPFWTILLSLIFLKEFIQKYQITSMVIAIIGMLFVV 137
Cdd:pfam00892  82 FYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLILLGVLLIL 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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