NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|504435586|ref|WP_014622688|]
View 

PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC [Streptococcus equi]

Protein Classification

PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC( domain architecture ID 10007905)

PTS mannose/fructose/sorbose/N-acetylgalactosamine-specific transporter subunit IIC is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system that catalyzes the phosphorylation of incoming sugar substrates (such as mannose, fructose, sorbose, and N-acetylgalactosamine) concomitantly with their translocation across the cell membrane

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 2-290 7.63e-76

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


:

Pssm-ID: 442929  Cd Length: 259  Bit Score: 231.93  E-value: 7.63e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586   2 IQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIAT 81
Cdd:COG3715    3 ISLIQAILIGLVAFLAGIDGLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVVNIGGAVPPDPALAGIIGT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  82 AFSVAQGIEPELAIsTIAVPVAALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVSL 161
Cdd:COG3715   83 ALAILSGQDPETAI-ALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFLLRAIPVFLALYF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 162 GGGAVDTVVKFIDhyEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLTAMLttiytnlqvaggalagvakd 241
Cdd:COG3715  162 GADAVQALLNAIP--AWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYL-------------------- 219

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 504435586 242 fnaapfkGLPMIGIAIIGLALATLHYKNGQQAPVAEqktGVSESGEIED 290
Cdd:COG3715  220 -------KLPLLAIAIIGVAIALIYYQLKKKKNAAA---AAASGDDDED 258
 
Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 2-290 7.63e-76

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 442929  Cd Length: 259  Bit Score: 231.93  E-value: 7.63e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586   2 IQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIAT 81
Cdd:COG3715    3 ISLIQAILIGLVAFLAGIDGLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVVNIGGAVPPDPALAGIIGT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  82 AFSVAQGIEPELAIsTIAVPVAALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVSL 161
Cdd:COG3715   83 ALAILSGQDPETAI-ALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFLLRAIPVFLALYF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 162 GGGAVDTVVKFIDhyEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLTAMLttiytnlqvaggalagvakd 241
Cdd:COG3715  162 GADAVQALLNAIP--AWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYL-------------------- 219

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 504435586 242 fnaapfkGLPMIGIAIIGLALATLHYKNGQQAPVAEqktGVSESGEIED 290
Cdd:COG3715  220 -------KLPLLAIAIIGVAIALIYYQLKKKKNAAA---AAASGDDDED 258
EII-Sor pfam03609
PTS system sorbose-specific iic component;
4-263 4.21e-69

PTS system sorbose-specific iic component;


Pssm-ID: 460987  Cd Length: 233  Bit Score: 213.81  E-value: 4.21e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586    4 WWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAF 83
Cdd:pfam03609   1 LIQAILIGLVAFLAGLDGLLGQFTLHRPLVAGTLVGLILGDVQTGLIIGATLQLMYLGVVTIGGAVPPDAALAGIIGTAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586   84 SVAQGIEPELAIsTIAVPVAALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIER-DYLMGAVPWALSRALPVFLAVSLG 162
Cdd:pfam03609  81 AILSGIGPEAAI-ALAVPVALLGQQLDNLVRTINSFFVHKADKYAEEGNYKGIERiHLLGPQLLGLLIRFIPVFLALYFG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  163 GGAVDTVVKFIdhYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLTAMLttiytnlqvaggalagvakdf 242
Cdd:pfam03609 160 ADAVQALLNAI--PEWLTNGLTVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYL--------------------- 216

                         250       260
                  ....*....|....*....|.
gi 504435586  243 naapfkGLPMIGIAIIGLALA 263
Cdd:pfam03609 217 ------KLPLIAIAIIGVAIA 231
PRK15065 PRK15065
mannose/fructose/sorbose family PTS transporter subunit IIC;
31-290 9.90e-19

mannose/fructose/sorbose family PTS transporter subunit IIC;


Pssm-ID: 237895  Cd Length: 262  Bit Score: 83.35  E-value: 9.90e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  31 PVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVA--QGIEPELAistIAVPVAAL-LV 107
Cdd:PRK15065  32 PLVACTLIGLVLGDLKTGIILGGTLEMIALGWMNIGAAVAPDAALASVISAILVIAghQGIGTGIA---IAIPLAAAgQV 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 108 YTdILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALP-VFLAVSLGGGAVDTVVKFIDhyEWLANGLTLA 186
Cdd:PRK15065 109 LT-IIVRTITVAFQHAADKAAEEGNFRAIEWLHVSALLLQALRIAIPaALVALAVGTSAVQSMLNAIP--EVLTGGLNIG 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 187 GKMLPGLGFAILLHYLPVKRNLHYLALGFGLtamlttiytnlqvaggalagvakdfnaAPFKGLPMIGIAIIGLALATLH 266
Cdd:PRK15065 186 GGMIVVVGYAMVINMMATRELMPFFYLGFVL---------------------------AAFTNLNLIALGVIGVVLALIY 238

                        250       260
                 ....*....|....*....|....
gi 504435586 267 YKNGQQAPVAEQKTGVSESGEIED 290
Cdd:PRK15065 239 LQLSPKYGRVAGGGAAGSGDPLDD 262
 
Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 2-290 7.63e-76

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 442929  Cd Length: 259  Bit Score: 231.93  E-value: 7.63e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586   2 IQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIAT 81
Cdd:COG3715    3 ISLIQAILIGLVAFLAGIDGLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVVNIGGAVPPDPALAGIIGT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  82 AFSVAQGIEPELAIsTIAVPVAALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVSL 161
Cdd:COG3715   83 ALAILSGQDPETAI-ALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFLLRAIPVFLALYF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 162 GGGAVDTVVKFIDhyEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLTAMLttiytnlqvaggalagvakd 241
Cdd:COG3715  162 GADAVQALLNAIP--AWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYL-------------------- 219

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 504435586 242 fnaapfkGLPMIGIAIIGLALATLHYKNGQQAPVAEqktGVSESGEIED 290
Cdd:COG3715  220 -------KLPLLAIAIIGVAIALIYYQLKKKKNAAA---AAASGDDDED 258
EII-Sor pfam03609
PTS system sorbose-specific iic component;
4-263 4.21e-69

PTS system sorbose-specific iic component;


Pssm-ID: 460987  Cd Length: 233  Bit Score: 213.81  E-value: 4.21e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586    4 WWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAF 83
Cdd:pfam03609   1 LIQAILIGLVAFLAGLDGLLGQFTLHRPLVAGTLVGLILGDVQTGLIIGATLQLMYLGVVTIGGAVPPDAALAGIIGTAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586   84 SVAQGIEPELAIsTIAVPVAALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIER-DYLMGAVPWALSRALPVFLAVSLG 162
Cdd:pfam03609  81 AILSGIGPEAAI-ALAVPVALLGQQLDNLVRTINSFFVHKADKYAEEGNYKGIERiHLLGPQLLGLLIRFIPVFLALYFG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  163 GGAVDTVVKFIdhYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLTAMLttiytnlqvaggalagvakdf 242
Cdd:pfam03609 160 ADAVQALLNAI--PEWLTNGLTVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYL--------------------- 216

                         250       260
                  ....*....|....*....|.
gi 504435586  243 naapfkGLPMIGIAIIGLALA 263
Cdd:pfam03609 217 ------KLPLIAIAIIGVAIA 231
PRK15065 PRK15065
mannose/fructose/sorbose family PTS transporter subunit IIC;
31-290 9.90e-19

mannose/fructose/sorbose family PTS transporter subunit IIC;


Pssm-ID: 237895  Cd Length: 262  Bit Score: 83.35  E-value: 9.90e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  31 PVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVA--QGIEPELAistIAVPVAAL-LV 107
Cdd:PRK15065  32 PLVACTLIGLVLGDLKTGIILGGTLEMIALGWMNIGAAVAPDAALASVISAILVIAghQGIGTGIA---IAIPLAAAgQV 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 108 YTdILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALP-VFLAVSLGGGAVDTVVKFIDhyEWLANGLTLA 186
Cdd:PRK15065 109 LT-IIVRTITVAFQHAADKAAEEGNFRAIEWLHVSALLLQALRIAIPaALVALAVGTSAVQSMLNAIP--EVLTGGLNIG 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 187 GKMLPGLGFAILLHYLPVKRNLHYLALGFGLtamlttiytnlqvaggalagvakdfnaAPFKGLPMIGIAIIGLALATLH 266
Cdd:PRK15065 186 GGMIVVVGYAMVINMMATRELMPFFYLGFVL---------------------------AAFTNLNLIALGVIGVVLALIY 238

                        250       260
                 ....*....|....*....|....
gi 504435586 267 YKNGQQAPVAEQKTGVSESGEIED 290
Cdd:PRK15065 239 LQLSPKYGRVAGGGAAGSGDPLDD 262
PRK09757 PRK09757
PTS N-acetylgalactosamine transporter subunit IIC;
31-215 2.74e-13

PTS N-acetylgalactosamine transporter subunit IIC;


Pssm-ID: 236621  Cd Length: 267  Bit Score: 68.33  E-value: 2.74e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586  31 PVFAGFISGIIMGDVQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAIStIAVPVAALLVYTD 110
Cdd:PRK09757  33 PIIVCTLTGAILGDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAKTAIG-LGLPFSLLMQYVI 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435586 111 ILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVSLGGGAVDTVVKFIDhyEWLANGLTLAGKML 190
Cdd:PRK09757 112 LFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAVIAFLCTYLAQGAMQALVKAMP--AWLTHGFEVAGGIL 189

                        170       180
                 ....*....|....*....|....*
gi 504435586 191 PGLGFAILLHYLPVKRNLHYLALGF 215
Cdd:PRK09757 190 PAVGFGLLLRVMFKAQYIPYLIAGF 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH