NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|504435831|ref|WP_014622933|]
View 

leucine-rich repeat domain-containing protein [Streptococcus equi]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 12134568)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
SCOP:  4003523

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
446-572 8.16e-24

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


:

Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 97.62  E-value: 8.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   446 IADNAFRNVNfhdktlrkydLESVTLPSTIQKIGAFAF-QSNNLESFEASEDLVEIGQGAFMNNRIEILALNDKLKVIGD 524
Cdd:pfam13306    3 IGSYAFYNCS----------LTSITIPSSLTSIGEYAFsNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGE 72
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 504435831   525 AAF-HINRIYAIVIPESVEVIGISAFRQNGAKHVMFmGDKLISIGEMAF 572
Cdd:pfam13306   73 YAFsNCSNLKSITLPSNLTSIGSYAFSNCSLKSITI-PSSVTTIGSYAF 120
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
218-336 1.03e-23

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


:

Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 97.23  E-value: 1.03e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   218 GAYA-----IKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSLQSIGDQAFFDNRLAGT 292
Cdd:pfam13306    4 GSYAfyncsLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNCSNLKS 83
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 504435831   293 LVLPKALKQLGERAFKSNRLTGLVFeGEGLSVLKEAAFQDNAFI 336
Cdd:pfam13306   84 ITLPSNLTSIGSYAFSNCSLKSITI-PSSVTTIGSYAFSNCSNL 126
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
520-644 7.77e-19

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


:

Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 83.36  E-value: 7.77e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   520 KVIGDAAFHINRIYAIVIPESVEVIGISAFRQ-NGAKHVMFmGDKLISIGEMAFLSNTLEEVDLSSlaGLKTIAVQAFAD 598
Cdd:pfam13306    1 TSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNcTSLKSITL-PSSLTSIGSYAFYNCSLTSITIPS--SLTSIGEYAFSN 77
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 504435831   599 N-HLRELKLPDSLMRIEAEAFKINRLQRVTVPDTVISISFNAFDHNS 644
Cdd:pfam13306   78 CsNLKSITLPSNLTSIGSYAFSNCSLKSITIPSSVTTIGSYAFSNCS 124
 
Name Accession Description Interval E-value
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
446-572 8.16e-24

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 97.62  E-value: 8.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   446 IADNAFRNVNfhdktlrkydLESVTLPSTIQKIGAFAF-QSNNLESFEASEDLVEIGQGAFMNNRIEILALNDKLKVIGD 524
Cdd:pfam13306    3 IGSYAFYNCS----------LTSITIPSSLTSIGEYAFsNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGE 72
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 504435831   525 AAF-HINRIYAIVIPESVEVIGISAFRQNGAKHVMFmGDKLISIGEMAF 572
Cdd:pfam13306   73 YAFsNCSNLKSITLPSNLTSIGSYAFSNCSLKSITI-PSSVTTIGSYAF 120
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
218-336 1.03e-23

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 97.23  E-value: 1.03e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   218 GAYA-----IKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSLQSIGDQAFFDNRLAGT 292
Cdd:pfam13306    4 GSYAfyncsLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNCSNLKS 83
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 504435831   293 LVLPKALKQLGERAFKSNRLTGLVFeGEGLSVLKEAAFQDNAFI 336
Cdd:pfam13306   84 ITLPSNLTSIGSYAFSNCSLKSITI-PSSVTTIGSYAFSNCSNL 126
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
520-644 7.77e-19

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 83.36  E-value: 7.77e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   520 KVIGDAAFHINRIYAIVIPESVEVIGISAFRQ-NGAKHVMFmGDKLISIGEMAFLSNTLEEVDLSSlaGLKTIAVQAFAD 598
Cdd:pfam13306    1 TSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNcTSLKSITL-PSSLTSIGSYAFYNCSLTSITIPS--SLTSIGEYAFSN 77
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 504435831   599 N-HLRELKLPDSLMRIEAEAFKINRLQRVTVPDTVISISFNAFDHNS 644
Cdd:pfam13306   78 CsNLKSITLPSNLTSIGSYAFSNCSLKSITIPSSVTTIGSYAFSNCS 124
 
Name Accession Description Interval E-value
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
446-572 8.16e-24

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 97.62  E-value: 8.16e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   446 IADNAFRNVNfhdktlrkydLESVTLPSTIQKIGAFAF-QSNNLESFEASEDLVEIGQGAFMNNRIEILALNDKLKVIGD 524
Cdd:pfam13306    3 IGSYAFYNCS----------LTSITIPSSLTSIGEYAFsNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGE 72
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 504435831   525 AAF-HINRIYAIVIPESVEVIGISAFRQNGAKHVMFmGDKLISIGEMAF 572
Cdd:pfam13306   73 YAFsNCSNLKSITLPSNLTSIGSYAFSNCSLKSITI-PSSVTTIGSYAF 120
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
218-336 1.03e-23

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 97.23  E-value: 1.03e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   218 GAYA-----IKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSLQSIGDQAFFDNRLAGT 292
Cdd:pfam13306    4 GSYAfyncsLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNCSNLKS 83
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 504435831   293 LVLPKALKQLGERAFKSNRLTGLVFeGEGLSVLKEAAFQDNAFI 336
Cdd:pfam13306   84 ITLPSNLTSIGSYAFSNCSLKSITI-PSSVTTIGSYAFSNCSNL 126
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
430-549 2.60e-19

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 84.90  E-value: 2.60e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   430 KHLVLPKNyqgqpLIAIADNAFRNVNfhdktlrkyDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN- 508
Cdd:pfam13306   14 TSITIPSS-----LTSIGEYAFSNCT---------SLKSITLPSSLTSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNCs 79
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 504435831   509 RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAF 549
Cdd:pfam13306   80 NLKSITLPSNLTSIGSYAFSNCSLKSITIPSSVTTIGSYAF 120
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
520-644 7.77e-19

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 83.36  E-value: 7.77e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   520 KVIGDAAFHINRIYAIVIPESVEVIGISAFRQ-NGAKHVMFmGDKLISIGEMAFLSNTLEEVDLSSlaGLKTIAVQAFAD 598
Cdd:pfam13306    1 TSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNcTSLKSITL-PSSLTSIGSYAFYNCSLTSITIPS--SLTSIGEYAFSN 77
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 504435831   599 N-HLRELKLPDSLMRIEAEAFKINRLQRVTVPDTVISISFNAFDHNS 644
Cdd:pfam13306   78 CsNLKSITLPSNLTSIGSYAFSNCSLKSITIPSSVTTIGSYAFSNCS 124
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
476-619 2.15e-18

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 82.21  E-value: 2.15e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   476 QKIGAFAFQSNNLESFEASEDLVEIGQGAFMNNRieilalndKLKvigdaafhinriyAIVIPESVEVIGISAFRQNGAK 555
Cdd:pfam13306    1 TSIGSYAFYNCSLTSITIPSSLTSIGEYAFSNCT--------SLK-------------SITLPSSLTSIGSYAFYNCSLT 59
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504435831   556 HVMFmGDKLISIGEMAFLSNT-LEEVDLSSlaGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFK 619
Cdd:pfam13306   60 SITI-PSSLTSIGEYAFSNCSnLKSITLPS--NLTSIGSYAFSNCSLKSITIPSSVTTIGSYAFS 121
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
256-352 1.85e-14

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 71.04  E-value: 1.85e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504435831   256 SISDYAFAHMSLSKLKLPKSLQSIGDQAFFDNRLAGTLVLPKALKQLGERAFKSNRLTGLVFEgEGLSVLKEAAFQDNAF 335
Cdd:pfam13306    2 SIGSYAFYNCSLTSITIPSSLTSIGEYAFSNCTSLKSITLPSSLTSIGSYAFYNCSLTSITIP-SSLTSIGEYAFSNCSN 80
                           90
                   ....*....|....*...
gi 504435831   336 I-SLVIPDSIQALEEDVF 352
Cdd:pfam13306   81 LkSITLPSNLTSIGSYAF 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH