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Conserved domains on  [gi|504529747|ref|WP_014716849|]
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MULTISPECIES: NAD(P)/FAD-dependent oxidoreductase [Pseudomonas]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11465281)

NAD(P)/FAD-dependent oxidoreductase such as polyamine oxidase (PAO), flavin-containing monoamine oxidases (MAOs), D-amino acid dehydrogenase, and linoleic acid isomerase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
1-328 7.62e-136

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


:

Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 388.85  E-value: 7.62e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFTARDRRFVNEVQRWQSNGWAEQ 80
Cdd:COG3380    2 SMPDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGGRMATRRLDGGRFDHGAQYFTARDPRFQALVEEWLAAGLVAP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  81 WKPQLYNFKSGQL-TPSPDEQIRWVGTPRMSAITRALLDDLPVEFGCRITEVFQGTQHWNLLDADGGNHGPFSHVIIATP 159
Cdd:COG3380   82 WTFDFVVLDADGLvSPRDDGEPRYVGVPGMNALAKHLAAGLDVRLGTRVTALERDGDGWRLTDEDGEEYGPFDAVVLAIP 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 160 APQATA--LLAAAPKLASAAAGVKMDPTWAIALAFDKPLDTPMEGCFVQDSPLDWLARNRSKPGRDTTlDTWVLHATSAW 237
Cdd:COG3380  162 APQAAAllEPSLAPELAAALASVRYRPCWAVMLGFDQPLDPDWDAAFVDDGPLAWIARDSSKPGRPGE-EAWVLHASPEW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 238 SKAHLDLPKEAVIEHLHGAFAELLHSAMPAPSFSLAHRWLYARPSSSHEFGVLADADLGLFVCGDWCLSGRVEGAWLSGQ 317
Cdd:COG3380  241 SREHLDDDPEEVAAALLAAFAELLGLPLAEPDWAQAHRWRYALPEAPLGAPFLWDADLGLGLCGDWCAGGRVEGAWLSGL 320

                        330
                 ....*....|.
gi 504529747 318 EAARRLIEHLQ 328
Cdd:COG3380  321 ALARALLARLA 331
 
Name Accession Description Interval E-value
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
1-328 7.62e-136

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 388.85  E-value: 7.62e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFTARDRRFVNEVQRWQSNGWAEQ 80
Cdd:COG3380    2 SMPDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGGRMATRRLDGGRFDHGAQYFTARDPRFQALVEEWLAAGLVAP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  81 WKPQLYNFKSGQL-TPSPDEQIRWVGTPRMSAITRALLDDLPVEFGCRITEVFQGTQHWNLLDADGGNHGPFSHVIIATP 159
Cdd:COG3380   82 WTFDFVVLDADGLvSPRDDGEPRYVGVPGMNALAKHLAAGLDVRLGTRVTALERDGDGWRLTDEDGEEYGPFDAVVLAIP 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 160 APQATA--LLAAAPKLASAAAGVKMDPTWAIALAFDKPLDTPMEGCFVQDSPLDWLARNRSKPGRDTTlDTWVLHATSAW 237
Cdd:COG3380  162 APQAAAllEPSLAPELAAALASVRYRPCWAVMLGFDQPLDPDWDAAFVDDGPLAWIARDSSKPGRPGE-EAWVLHASPEW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 238 SKAHLDLPKEAVIEHLHGAFAELLHSAMPAPSFSLAHRWLYARPSSSHEFGVLADADLGLFVCGDWCLSGRVEGAWLSGQ 317
Cdd:COG3380  241 SREHLDDDPEEVAAALLAAFAELLGLPLAEPDWAQAHRWRYALPEAPLGAPFLWDADLGLGLCGDWCAGGRVEGAWLSGL 320

                        330
                 ....*....|.
gi 504529747 318 EAARRLIEHLQ 328
Cdd:COG3380  321 ALARALLARLA 331
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 12-324 2.27e-12

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 67.52  E-value: 2.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   12 IAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFT-------------------------------- 59
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHgaqppllallkelgledrlvlpdpapfytvlf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   60 ARDRRFVNEVQRWQSnGWA-----------------------------------------------------------EQ 80
Cdd:pfam01593  81 AGGRRYPGDFRRVPA-GWEgllefgrllsipeklrlglaalasdaldefdlddfslaesllflgrrgpgdvevwdrliDP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   81 WKPQLYNFKSGQLTPSPDEQIR-----------------WVGTPRMSAITRALLDDLP---VEFGCRITEVfqgtqHWN- 139
Cdd:pfam01593 160 ELFAALPFASGAFAGDPSELSAglalpllwallgeggslLLPRGGLGALPDALAAQLLggdVRLNTRVRSI-----DREg 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  140 ---LLDADGGNHGPFSHVIIATPAP---QATALLAAAPKLASAAAGVKMDPTWAIALAFDKPLdTPMEGCFVQDSPL--- 210
Cdd:pfam01593 235 dgvTVTLTDGEVIEADAVIVTVPLGvlkRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKF-WPDLGLLGLLSELltg 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  211 -----DWLA-RNRSKPGRDTTLDTWVLHATSAWskaHLD-LPKEAVIEHLHGAFAELLHSAMPAPSFSLAHRW------- 276
Cdd:pfam01593 314 lgtafSWLTfPNRAPPGKGLLLLVYVGPGDRAR---ELEgLSDEELLQAVLRDLRKLFGEEAPEPLRVLVSDWhtdpwpr 390

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 504529747  277 ----LYARPSSSHEFGVLA-DADLGLFVCGDWC---LSGRVEGAWLSGQEAARRLI 324
Cdd:pfam01593 391 gsysLPQYGPGHDDYRPLArTPDPGLFFAGEHTstgYPGTVEGAIESGRRAARAVL 446
PRK07233 PRK07233
hypothetical protein; Provisional
 5-43 1.11e-07

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 52.97  E-value: 1.11e-07
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSS 43
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAAS 40
 
Name Accession Description Interval E-value
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
1-328 7.62e-136

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 388.85  E-value: 7.62e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFTARDRRFVNEVQRWQSNGWAEQ 80
Cdd:COG3380    2 SMPDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGGRMATRRLDGGRFDHGAQYFTARDPRFQALVEEWLAAGLVAP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  81 WKPQLYNFKSGQL-TPSPDEQIRWVGTPRMSAITRALLDDLPVEFGCRITEVFQGTQHWNLLDADGGNHGPFSHVIIATP 159
Cdd:COG3380   82 WTFDFVVLDADGLvSPRDDGEPRYVGVPGMNALAKHLAAGLDVRLGTRVTALERDGDGWRLTDEDGEEYGPFDAVVLAIP 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 160 APQATA--LLAAAPKLASAAAGVKMDPTWAIALAFDKPLDTPMEGCFVQDSPLDWLARNRSKPGRDTTlDTWVLHATSAW 237
Cdd:COG3380  162 APQAAAllEPSLAPELAAALASVRYRPCWAVMLGFDQPLDPDWDAAFVDDGPLAWIARDSSKPGRPGE-EAWVLHASPEW 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 238 SKAHLDLPKEAVIEHLHGAFAELLHSAMPAPSFSLAHRWLYARPSSSHEFGVLADADLGLFVCGDWCLSGRVEGAWLSGQ 317
Cdd:COG3380  241 SREHLDDDPEEVAAALLAAFAELLGLPLAEPDWAQAHRWRYALPEAPLGAPFLWDADLGLGLCGDWCAGGRVEGAWLSGL 320

                        330
                 ....*....|.
gi 504529747 318 EAARRLIEHLQ 328
Cdd:COG3380  321 ALARALLARLA 331
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 12-324 2.27e-12

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 67.52  E-value: 2.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   12 IAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFT-------------------------------- 59
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHgaqppllallkelgledrlvlpdpapfytvlf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   60 ARDRRFVNEVQRWQSnGWA-----------------------------------------------------------EQ 80
Cdd:pfam01593  81 AGGRRYPGDFRRVPA-GWEgllefgrllsipeklrlglaalasdaldefdlddfslaesllflgrrgpgdvevwdrliDP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   81 WKPQLYNFKSGQLTPSPDEQIR-----------------WVGTPRMSAITRALLDDLP---VEFGCRITEVfqgtqHWN- 139
Cdd:pfam01593 160 ELFAALPFASGAFAGDPSELSAglalpllwallgeggslLLPRGGLGALPDALAAQLLggdVRLNTRVRSI-----DREg 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  140 ---LLDADGGNHGPFSHVIIATPAP---QATALLAAAPKLASAAAGVKMDPTWAIALAFDKPLdTPMEGCFVQDSPL--- 210
Cdd:pfam01593 235 dgvTVTLTDGEVIEADAVIVTVPLGvlkRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKF-WPDLGLLGLLSELltg 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  211 -----DWLA-RNRSKPGRDTTLDTWVLHATSAWskaHLD-LPKEAVIEHLHGAFAELLHSAMPAPSFSLAHRW------- 276
Cdd:pfam01593 314 lgtafSWLTfPNRAPPGKGLLLLVYVGPGDRAR---ELEgLSDEELLQAVLRDLRKLFGEEAPEPLRVLVSDWhtdpwpr 390

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 504529747  277 ----LYARPSSSHEFGVLA-DADLGLFVCGDWC---LSGRVEGAWLSGQEAARRLI 324
Cdd:pfam01593 391 gsysLPQYGPGHDDYRPLArTPDPGLFFAGEHTstgYPGTVEGAIESGRRAARAVL 446
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-69 2.64e-12

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 61.01  E-value: 2.64e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504529747    7 IIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFTARD----RRFVNEV 69
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPGYVFDYGAHIFHGSDepnvRDLLDEL 67
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
5-327 1.77e-10

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 61.48  E-value: 1.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAG--ALDMGAQYF------------------------ 58
Cdd:COG1231   10 VVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDglYAELGAMRIppshtnllalarelglplepfpne 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  59 -----------TAR------------------DRRFVNEVQRW----------------QSNGWAEQWKPQLYNFKSGQL 93
Cdd:COG1231   90 ngnallylggkRVRageiaadlrgvaellaklLRALAAALDPWahpaaeldreslaewlRRNGASPSARRLLGLLGAGEY 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747  94 TPSPDEQ--------IRWVGTPR--------MSAITRALLDDLP--VEFGCRITEVFQGTQHWNLLDADGGNHGpFSHVI 155
Cdd:COG1231  170 GADPDELslldllryAASAGGGAqqfrivggMDQLPRALAAELGdrIRLGAPVTRIRQDGDGVTVTTDDGGTVR-ADAVI 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 156 IATPAPQATA---LLAAAPKLASAAAGVKMDPTWAIALAFDKPL---DTPMEGCFVQDSPLD--WLARNRSKPGRDTtld 227
Cdd:COG1231  249 VTVPPSVLRRiefDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFweeDGLYGGISLTDLPIRqtWYPSNGPDGGAGV--- 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 228 tWVLHATSAWSKAHLDLPKEAVIEHLHGAFAELLHSAMPAPSFSLAHRWL----------YARPSSSHEFG-VLADADLG 296
Cdd:COG1231  326 -LLGYVGGDDARALAALSPEERVAAALEQLARIFGVYAAEPVDYVSTDWGrdpwsrgayaAAPPGQLTAAGpALAEPDGR 404

                        410       420       430
                 ....*....|....*....|....*....|....
gi 504529747 297 LFVCGDWC---LSGRVEGAWLSGQEAARRLIEHL 327
Cdd:COG1231  405 IHFAGEHTsdeWPGWVEGALESGERAAAEILARL 438
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-67 3.47e-08

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 54.45  E-value: 3.47e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504529747   3 VPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFTARDRRFVN 67
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEVDGFRIDRGPHSFLTRDPEVLE 66
PRK07233 PRK07233
hypothetical protein; Provisional
 5-43 1.11e-07

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 52.97  E-value: 1.11e-07
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSS 43
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAAS 40
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 122-327 1.92e-07

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 52.16  E-value: 1.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 122 VEFGCRITEVFQGTQHWNLLDADGGNHGPFSHVIIATPAPQATALLAAAPKLASAAAGVKMDPTW--AIALAFDKPLDTP 199
Cdd:COG3349  229 VRLGTRVRALEFDGGRVTGLVLADGETVPADAVVLAVPPEVAARLLPELARLPELGLLAPLEYSPivNVHLWLDRPVTLG 308

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 200 MEGCF-VQDSPLDWL-ARNRSKPGRDttldtWVLHATSAWSKAHLDLPKEAVIEHLHGAFAELL---HSAMPAPSFSLA- 273
Cdd:COG3349  309 PPPFAgLVGSTSQWVfDRGAGDGGQG-----GVLSVVISAADRLLDLSREELAAEVWAELAALLpaaREALPVWSRVVRe 383

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504529747 274 HRWLYA--------RPSsshefgvlADADL-GLFVCGDW-------CLsgrvEGAWLSGQEAARRLIEHL 327
Cdd:COG3349  384 KRATFAatpgsdrlRPG--------ARTPIpNLFLAGDWtatglpaTM----EGAVRSGRRAANAILARL 441
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 5-61 3.01e-07

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 51.77  E-value: 3.01e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 504529747   5 IAIIGTGIAGLSAARALQDAG--HAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFTAR 61
Cdd:PRK11883   3 VAIIGGGITGLSAAYRLHKKGpdADITLLEASDRLGGKIQTVRKDGFPIELGPESFLAR 61
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-69 6.02e-07

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 50.62  E-value: 6.02e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQYFTARD--RRFVNEV 69
Cdd:COG1233    2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFERPGFRFDVGPSVLTMPGvlERLFREL 72
PLN02268 PLN02268
probable polyamine oxidase
 7-57 9.63e-07

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 50.07  E-value: 9.63e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 504529747   7 IIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGALDMGAQY 57
Cdd:PLN02268   5 VIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFPVDMGASW 55
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
5-39 2.12e-06

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 48.96  E-value: 2.12e-06
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 504529747   5 IAIIGTGIAGLSAARALQDAgHAVQLFDKSRGSGG 39
Cdd:COG2907    6 IAVIGSGISGLTAAWLLSRR-HDVTLFEANDRLGG 39
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 2-39 3.30e-06

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 48.32  E-value: 3.30e-06
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 504529747   2 TVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGG 39
Cdd:COG2072    6 HVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGG 43
PLN02487 PLN02487
zeta-carotene desaturase
 5-58 5.23e-06

zeta-carotene desaturase


Pssm-ID: 215268 [Multi-domain]  Cd Length: 569  Bit Score: 47.87  E-value: 5.23e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSS-KRSDAGALDMGAQYF 58
Cdd:PLN02487  78 VAIIGAGLAGMSTAVELLDQGHEVDIYESRPFIGGKVGSfVDKNGNHIEMGLHVF 132
PRK06753 PRK06753
hypothetical protein; Provisional
 5-33 8.45e-06

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 46.99  E-value: 8.45e-06
                         10        20
                 ....*....|....*....|....*....
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDK 33
Cdd:PRK06753   3 IAIIGAGIGGLTAAALLQEQGHEVKVFEK 31
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-36 1.47e-05

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 46.08  E-value: 1.47e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRG 36
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPP 37
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-66 1.62e-05

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 46.05  E-value: 1.62e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDksRGSGGRMSSKRSdAGALdmGAQYFTARDRRFV 66
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLE--RGRPGSGASGRN-AGQL--RPGLAALADRALV 61
PLN03000 PLN03000
amine oxidase
 5-59 6.69e-05

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 44.63  E-value: 6.69e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAG----ALDMGAQYFT 59
Cdd:PLN03000 187 VVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGRVYTKKMEANrvgaAADLGGSVLT 245
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 5-41 6.84e-05

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 44.33  E-value: 6.84e-05
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRM 41
Cdd:PRK12814 196 VAIIGAGPAGLTAAYYLLRKGHDVTIFDANEQAGGMM 232
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 5-41 1.48e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 43.33  E-value: 1.48e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRM 41
Cdd:PRK12771 140 VAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLGGMM 176
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 5-71 1.50e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 43.16  E-value: 1.50e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504529747    5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRmSSKRSdAGALdmGAQYFTARDRRFVNEVQR 71
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSG-ASGRN-AGLI--HPGLRYLEPSELARLALE 64
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 5-39 1.56e-04

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 43.23  E-value: 1.56e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGG 39
Cdd:PRK12810 146 VAVVGSGPAGLAAADQLARAGHKVTVFERADRIGG 180
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 5-33 1.87e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 42.81  E-value: 1.87e-04
                         10        20
                 ....*....|....*....|....*....
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDK 33
Cdd:COG0493  124 VAVVGSGPAGLAAAYQLARAGHEVTVFEA 152
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
5-41 3.27e-04

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 42.15  E-value: 3.27e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRM 41
Cdd:COG1148  143 ALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGRA 179
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 5-59 7.51e-04

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 40.74  E-value: 7.51e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGG---------RMSSKRSDAGALDM---GAQYFT 59
Cdd:PRK12770  21 VAIIGAGPAGLAAAGYLACLGYEVHVYDKLPEPGGlmlfgipefRIPIERVREGVKELeeaGVVFHT 87
PLN02976 PLN02976
amine oxidase
 5-59 8.95e-04

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 41.01  E-value: 8.95e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 504529747    5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGGRMSSKRSDAGA-LDMGAQYFT 59
Cdd:PLN02976  696 IIVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYTDRSSLSVpVDLGASIIT 751
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 5-33 1.10e-03

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 40.55  E-value: 1.10e-03
                         10        20
                 ....*....|....*....|....*....
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDK 33
Cdd:PRK11749 143 VAVIGAGPAGLTAAHRLARKGYDVTIFEA 171
PRK07236 PRK07236
hypothetical protein; Provisional
 5-38 1.20e-03

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 40.29  E-value: 1.20e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKS------RGSG 38
Cdd:PRK07236   9 AVVIGGSLGGLFAALLLRRAGWDVDVFERSpteldgRGAG 48
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 5-35 2.19e-03

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 39.62  E-value: 2.19e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSR 35
Cdd:PRK12409   4 IAVIGAGITGVTTAYALAQRGYQVTVFDRHR 34
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 1-33 2.80e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 39.39  E-value: 2.80e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDK 33
Cdd:PRK06292   2 EKYDVIVIGAGPAGYVAARRAAKLGKKVALIEK 34
NAD_binding_2 pfam03446
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of ...
 5-35 2.83e-03

NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.


Pssm-ID: 427298 [Multi-domain]  Cd Length: 159  Bit Score: 37.83  E-value: 2.83e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 504529747    5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSR 35
Cdd:pfam03446   2 IGFIGLGVMGSPMALNLLKAGYTVTVYNRTP 32
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 5-32 3.19e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 38.84  E-value: 3.19e-03
                          10        20
                  ....*....|....*....|....*...
gi 504529747    5 IAIIGTGIAGLSAARALQDAGHAVQLFD 32
Cdd:pfam07992   3 VVVIGGGPAGLAAALTLAQLGGKVTLIE 30
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 5-39 3.30e-03

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 39.07  E-value: 3.30e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGG 39
Cdd:PLN02172  13 VAVIGAGAAGLVAARELRREGHTVVVFEREKQVGG 47
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
1-71 5.85e-03

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 38.09  E-value: 5.85e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGgrmsskrsDAGA-LDMGAQYFTARDRRFVNEVQR 71
Cdd:PRK08163   3 KVTPVLIVGGGIGGLAAALALARQGIKVKLLEQAAEIG--------EIGAgIQLGPNAFSALDALGVGEAAR 66
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
5-32 6.04e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 37.96  E-value: 6.04e-03
                         10        20
                 ....*....|....*....|....*...
gi 504529747   5 IAIIGTGIAGLSAARALQDAGHAVQLFD 32
Cdd:PRK07494  10 IAVIGGGPAGLAAAIALARAGASVALVA 37
PRK07538 PRK07538
hypothetical protein; Provisional
 4-35 6.30e-03

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 37.95  E-value: 6.30e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 504529747   4 PIAIIGTGIAGLSAARALQDAGHAVQLFDKSR 35
Cdd:PRK07538   2 KVLIAGGGIGGLTLALTLHQRGIEVVVFEAAP 33
PRK07208 PRK07208
hypothetical protein; Provisional
 1-39 7.27e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 37.95  E-value: 7.27e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 504529747   1 MTVPIAIIGTGIAGLSAARALQDAGHAVQLFDKSRGSGG 39
Cdd:PRK07208   3 NKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGG 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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