|
Name |
Accession |
Description |
Interval |
E-value |
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
1-442 |
0e+00 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 756.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 1 MSNLSlDFSDNAFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVER 80
Cdd:COG2256 1 MDDAA-AEASAANAPLAERMRPRTLDEVVGQEHLLGPGKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANATDAEFVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 81 ISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTIFFIGATTENPSFELNSALLSRARVY 160
Cdd:COG2256 80 LSAVTSGVKDIREVIEEARERRAYGRRTILFVDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNSALLSRCRVF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 161 LLKSLTAEDIEKVLTQAMDDKARGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEvdDAGKRVLKPELLTEI 240
Cdd:COG2256 160 VLKPLSEEDLEQLLERALADDERGLGGYKLELDDEALEALARLADGDARRALNALELAVLSAP--PDGVIEITLELVEEA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 241 AGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVALSAWDC 320
Cdd:COG2256 238 LQRRALRYDKDGDEHYDLISAFIKSIRGSDPDAALYWLARMLEAGEDPRFIARRLVIMASEDIGLADPQALQIAVAAAQA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 321 FTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAAMSDARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEPNAYa 400
Cdd:COG2256 318 VERLGMPEGRIALAQAVIYLATAPKSNAAYLAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPGGY- 396
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 504696103 401 AGEEYFPQEMAQTRYYHPTNRGLEGKIGEKLTWLAGQDQNSP 442
Cdd:COG2256 397 VGQQYLPDELKGRRYYEPTERGFERKIKERLEKLRKLRRGAR 438
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
15-439 |
0e+00 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 746.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 15 PLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREA 94
Cdd:PRK13342 1 PLAERMRPKTLDEVVGQEHLLGPGKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGATDAPFEALSAVTSGVKDLREV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 95 IERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTIFFIGATTENPSFELNSALLSRARVYLLKSLTAEDIEKVL 174
Cdd:PRK13342 81 IEEARQRRSAGRRTILFIDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNPALLSRAQVFELKPLSEEDIEQLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 175 TQAMDDKARGYggqdIVLPDETRRAIAELVNGDARRALNTLEMMADMaevddagKRVLKPELLTEIAGERSARFDNKGDR 254
Cdd:PRK13342 161 KRALEDKERGL----VELDDEALDALARLANGDARRALNLLELAALG-------VDSITLELLEEALQKRAARYDKDGDE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 255 FYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVALSAWDCFTRVGPAEGERAIA 334
Cdd:PRK13342 230 HYDLISALHKSIRGSDPDAALYYLARMLEAGEDPLFIARRLVIIASEDIGLADPNALQVAVAAADAVERIGMPEGRIALA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 335 QAIVYLACAPKSNAVYTAFKAAMSDARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEPNAYaAGEEYFPQEMAQTR 414
Cdd:PRK13342 310 QAVIYLALAPKSNAAYTAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPNGY-VGQQYLPDELKGKR 388
|
410 420
....*....|....*....|....*
gi 504696103 415 YYHPTNRGLEGKIGEKLTWLAGQDQ 439
Cdd:PRK13342 389 YYEPTERGFEKKIKERLEKLKDKNR 413
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
15-431 |
8.60e-153 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 450.66 E-value: 8.60e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 15 PLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREA 94
Cdd:PRK13341 17 PLADRLRPRTLEEFVGQDHILGEGRLLRRAIKADRVGSLILYGPPGVGKTTLARIIANHTRAHFSSLNAVLAGVKDLRAE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 95 IERARQNRNA-GRRTILFVDEVHRFNKSQQDAFLPHIEDGTIFFIGATTENPSFELNSALLSRARVYLLKSLTAEDIEKV 173
Cdd:PRK13341 97 VDRAKERLERhGKRTILFIDEVHRFNKAQQDALLPWVENGTITLIGATTENPYFEVNKALVSRSRLFRLKSLSDEDLHQL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 174 LTQAMDDKARGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDAGKRVLKPELLTEIAGERSARFDNKGD 253
Cdd:PRK13341 177 LKRALQDKERGYGDRKVDLEPEAEKHLVDVANGDARSLLNALELAVESTPPDEDGLIDITLAIAEESIQQRAVLYDKEGD 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 254 RFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVALSAWDCFTRVGPAEGERAI 333
Cdd:PRK13341 257 AHFDTISAFIKSLRGSDPDAALYWLARMVEAGEDPRFIFRRMLIAASEDVGLADPQALVVVEACAAAFERVGLPEGLYPL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 334 AQAIVYLACAPKSNAVYTAFKaAMSDARERPDYDVPVHLRNaPTKLMKEMGYGQEYRYAHDEPNAYAAgEEYFPQEMAQT 413
Cdd:PRK13341 337 AQAALYLATAPKSNSVLGFFD-ALKKVREEQVQDVPNHLRD-ANRDGKAFGDGVGYRYPHAFRDHWVA-QQYLPEALQGE 413
|
410
....*....|....*...
gi 504696103 414 RYYHPTNRGLEGKIGEKL 431
Cdd:PRK13341 414 VFWQPSRQGWEGERRERL 431
|
|
| MgsA_C |
pfam12002 |
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA ... |
268-426 |
5.58e-91 |
|
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication. Additionally, MgsA may play a role in chromosomal segregation. This is consistent with a report that MgsA co-localizes with the replisome and affects chromosome segregation. This domain represents the C terminal region of MgsA.
Pssm-ID: 463426 [Multi-domain] Cd Length: 158 Bit Score: 272.68 E-value: 5.58e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 268 GSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVALSAWDCFTRVGPAEGERAIAQAIVYLACAPKSN 347
Cdd:pfam12002 1 GSDPDAALYWLARMLEAGEDPLFIARRLVIIASEDIGLADPQALVVAVAAAQAVERIGMPEARIPLAQAVIYLALAPKSN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 348 AVYTAFKAAMSDARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEPNAYaAGEEYFPQEMAQTRYYHPTNRGLEGK 426
Cdd:pfam12002 81 SAYLAIDAALADVREGGSLPVPLHLRNAPTKLMKKLGYGKGYKYPHDYPNGY-VKQQYLPDELKGRRYYEPTDNGYEKK 158
|
|
| PRK14700 |
PRK14700 |
recombination factor protein RarA; Provisional |
127-431 |
1.34e-73 |
|
recombination factor protein RarA; Provisional
Pssm-ID: 173163 [Multi-domain] Cd Length: 300 Bit Score: 233.37 E-value: 1.34e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 127 LPHIEDGTIFFIGATTENPSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDdKARGYGGQDIVLPDETRRAIAELVNG 206
Cdd:PRK14700 1 MPYVESGKIILIGATTENPTYYLNDALVSRLFILRLKRLSLVATQKLIEKALS-QDEVLAKHKFKIDDGLYNAMHNYNEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 207 DARRALNTLEMMAdmaEVDDAGKRV-LKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAG 285
Cdd:PRK14700 80 DCRKILNLLERMF---LISTRGDEIyLNKELFDQAVGETSRDFHREGKEFYEQLSAFHKSVRGTDPDAAIFWLSVMLDNG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 286 GDPLYVARRCLAIASEDVGNADPRAMQVALSAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAAMSDARERPD 365
Cdd:PRK14700 157 VDPLVIARRMLCIASEDIGNADPQALRVAMDAWNAYEKLGMPEGRLVLAQAAIYLAVAPKSNACYKALAQAQQLVKSLGN 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504696103 366 YDVPVHLRNAPTklmkemgygQEYRYAHDEPNAYAAgEEYFPQEMAQTrYYHPTNRGLEGKIGEKL 431
Cdd:PRK14700 237 IDVPQHLKNYKD---------SNYLYPHNYPNSYVI-QQYLPDNIIQN-FYQPTASGFEAKIKTKL 291
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
186-267 |
1.03e-29 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 110.64 E-value: 1.03e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 186 GGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDaGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKS 265
Cdd:pfam16193 1 GGLKIELDDEALEALAELADGDARRALNALELAVLSTPPDD-GGIHITLEILEEALQRKALRYDKDGDEHYDLISAFHKS 79
|
..
gi 504696103 266 VR 267
Cdd:pfam16193 80 IR 81
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
53-165 |
4.16e-22 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 91.50 E-value: 4.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNrnagRRTILFVDEVHRFNKSQ--- 122
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGselvskyVGESEKRLRELFEAAKKL----APCVIFIDEIDALAGSRgsg 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 504696103 123 --------QDAFLPHIEDGT-----IFFIGATTEnpSFELNSALLSRARVYLLKSL 165
Cdd:pfam00004 77 gdsesrrvVNQLLTELDGFTssnskVIVIAATNR--PDKLDPALLGRFDRIIEFPL 130
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
22-298 |
1.78e-20 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 92.18 E-value: 1.78e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 22 PENLAQYIGQQHLLaagKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYAN------------------------A 76
Cdd:COG2812 6 PQTFDDVVGQEHVV---RTLKNALASGRLaHAYLFTGPRGVGKTTLARILAKALNcengptgepcgecescraiaagshP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 DVERISAVTS--GVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFL-------PHiedgTIfFIGATTenpsf 147
Cdd:COG2812 83 DVIEIDAEASniGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLktleeppPH----VV-FILATT----- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 148 ELNSAL---LSRARVYLLKSLTAEDIEKVLTQAMDDKargyggqDIVLPDETRRAIAELVNGDARRALNTLemmadmaev 224
Cdd:COG2812 153 EPQKLLptiLSRCQRFDFRRLPPEEIAEHLAKIAERE-------GIEIEPEALALIARAADGSMRDALSLL--------- 216
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504696103 225 DDAgkrvlkpelltEIAGERSARfdnkgDRFYDLISALHKSVrgsaPDAALYWYARIITAGGDPLYVARRCLAI 298
Cdd:COG2812 217 DQA-----------IAFGLLDRR-----ELLLDLLEALLAGD----VAALLALAEELAKRGRDLKRFLDDLLSL 270
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
41-284 |
2.69e-18 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 84.64 E-value: 2.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 41 LPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARY-----------------------ANADVERISAV----TSGVKEIR 92
Cdd:COG0470 8 LLAAAESGRLpHALLLHGPPGIGKTTLALALARDllcenpeggkacgqchsrlmaagNHPDLLELNPEeksdQIGIDQIR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 93 EAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED---GTIFFIgaTTENPSFELNSaLLSRARVYLLKSLTAED 169
Cdd:COG0470 88 ELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEppkNTPFIL--IANDPSRLLPT-IRSRCQVIRFRPPSEEE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 170 IEKVLTQAmddkargyggqdiVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDA----GKRVLKPELLTEIAGERS 245
Cdd:COG0470 165 ALAWLREE-------------GVDEDALEAILRLAGGDPRAAINLLQALAGRKELLEDlaalLSRDRALELLDALLKAEA 231
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 504696103 246 ArfdnkgDRFYDLISALHKSVRGSAPDAALY-WYARIITA 284
Cdd:COG0470 232 L------ELLDWLLKWLLDNLPLEYAGEDLArAYEALSEA 265
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
12-185 |
3.80e-18 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 87.07 E-value: 3.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLH-SMILWGPPGTGKTTLAEVIARYANAD------------- 77
Cdd:PRK08691 2 AYQVLARKWRPKTFADLVGQEHVVKA---LQNALDEGRLHhAYLLTGTRGVGKTTIARILAKSLNCEnaqhgepcgvcqs 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 ------------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTE 143
Cdd:PRK08691 79 ctqidagryvdlLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEppEHVKFILATTD 158
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 504696103 144 npSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDKARGY 185
Cdd:PRK08691 159 --PHKVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAY 198
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
17-218 |
3.97e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 85.70 E-value: 3.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 17 AARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYAN-----ADVERIS-------- 82
Cdd:PRK14970 8 ARKYRPQTFDDVVGQSHITNT---LLNAIENNHLAQALLFcGPRGVGKTTCARILARKINqpgydDPNEDFSfnifelda 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 83 AVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTEnpSFELNSALLSRARVY 160
Cdd:PRK14970 85 ASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEppAHAIFILATTE--KHKIIPTILSRCQIF 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 161 LLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRALNTLEMM 218
Cdd:PRK14970 163 DFKRITIKDIKEHLAGIAVK-------EGIKFEDDALHIIAQKADGALRDALSIFDRV 213
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
165-242 |
7.50e-18 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 77.67 E-value: 7.50e-18
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 165 LTAEDIEKVLTQAMDDKARGyGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEvdDAGKRVLKPELLTEIAG 242
Cdd:cd18139 1 LSEEDLEKLLKRALEDKERG-GDRKVTIDDEALELLAEAADGDARSALNLLELAVLSAE--EDGGIVITLEDLEEVLQ 75
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
9-242 |
6.32e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 79.90 E-value: 6.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 9 SDNAFQPLAARMRPENLAQYIGQQHLLaagKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYAN------------ 75
Cdd:PRK06645 4 SSNQYIPFARKYRPSNFAELQGQEVLV---KVLSYTILNDRLaGGYLLTGIRGVGKTTSARIIAKAVNcsalitenttik 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 76 ----------------ADVERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIF 136
Cdd:PRK06645 81 tceqctncisfnnhnhPDIIEIDAASkTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEppPHII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 137 FIGATTENPsfELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRALNTLE 216
Cdd:PRK06645 161 FIFATTEVQ--KIPATIISRCQRYDLRRLSFEEIFKLLEYITKQ-------ENLKTDIEALRIIAYKSEGSARDAVSILD 231
|
250 260
....*....|....*....|....*.
gi 504696103 217 MMADMAEVDDagkRVLKPELLTEIAG 242
Cdd:PRK06645 232 QAASMSAKSD---NIISPQVINQMLG 254
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
21-219 |
7.69e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 79.86 E-value: 7.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 21 RPENLAQYIGQQHLLAAgkpLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA---------------------DV 78
Cdd:PRK07133 13 RPKTFDDIVGQDHIVQT---LKNIIKSNKIsHAYLFSGPRGTGKTSVAKIFANALNCshktdllepcqecienvnnslDI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 79 ERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTENPSFELnsALLS 155
Cdd:PRK07133 90 IEMDAASnNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEppKHVIFILATTEVHKIPL--TILS 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504696103 156 RARVYLLKSLTAEDIEKVLTQAMDDKArgyggqdIVLPDETRRAIAELVNGDARRALNTLEMMA 219
Cdd:PRK07133 168 RVQRFNFRRISEDEIVSRLEFILEKEN-------ISYEKNALKLIAKLSSGSLRDALSIAEQVS 224
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
29-156 |
1.01e-15 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 74.10 E-value: 1.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 29 IGQQHLLAAGKplpRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRT 108
Cdd:cd00009 1 VGQEEAIEALR---EALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLF 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504696103 109 ---------ILFVDEVHRFNKSQQDAFLPHIED--------GTIFFIGATTENPSFELNSALLSR 156
Cdd:cd00009 78 elaekakpgVLFIDEIDSLSRGAQNALLRVLETlndlridrENVRVIGATNRPLLGDLDRALYDR 142
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
20-132 |
1.48e-15 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 73.69 E-value: 1.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 20 MRPENLAQYIGQQHLLAAgkpLPRAIEAG-----HLHSMILWGPPGTGKTTLAEVIARYANADVErisaVTSGvkeirEA 94
Cdd:pfam05496 1 LRPRTLDEYIGQEKVKEN---LKIFIEAAkqrgeALDHVLLYGPPGLGKTTLANIIANEMGVNIR----ITSG-----PA 68
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 504696103 95 IERARQN----RNAGRRTILFVDEVHRFNKSQQDAFLPHIED 132
Cdd:pfam05496 69 IERPGDLaailTNLEPGDVLFIDEIHRLNRAVEEILYPAMED 110
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
14-225 |
7.38e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 76.34 E-value: 7.38e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 14 QPLAARMRPENLAQYIGQQHllaAGKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA---------------- 76
Cdd:PRK14962 2 EALYRKYRPKTFSEVVGQDH---VKKLIINALKKNSIsHAYIFAGPRGTGKTTVARILAKSLNCenrkgvepcnecracr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 --------DVERISAVTS-GVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTeNP 145
Cdd:PRK14962 79 sidegtfmDVIELDAASNrGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEppSHVVFVLATT-NL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 146 SfELNSALLSRARVYLLKSLTAEDIEKVLTQAMddKARGyggqdIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVD 225
Cdd:PRK14962 158 E-KVPPTIISRCQVIEFRNISDELIIKRLQEVA--EAEG-----IEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGK 229
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
13-267 |
4.53e-14 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 74.31 E-value: 4.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 13 FQPLAARMRPENLAQYIGQQHLlaaGKPLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYANADVERIS--------- 82
Cdd:PRK14960 2 YQVLARKYRPRNFNELVGQNHV---SRALSSALERGRLHHAYLFtGTRGVGKTTIARILAKCLNCETGVTStpcevcatc 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 83 -AVTSG---------------VKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGT--IFFIGATTEn 144
Cdd:PRK14960 79 kAVNEGrfidlieidaasrtkVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPehVKFLFATTD- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 145 PSfELNSALLSRARVYLLKSLTAEDIEKVLTqAMDDKARGYGGQDIVLpdetrrAIAELVNGDARRALNtlemMADMAEV 224
Cdd:PRK14960 158 PQ-KLPITVISRCLQFTLRPLAVDEITKHLG-AILEKEQIAADQDAIW------QIAESAQGSLRDALS----LTDQAIA 225
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 504696103 225 ddAGKRVLKPELLTEIAG--ERSArfdnkgdrFYDLISALHKSVR 267
Cdd:PRK14960 226 --YGQGAVHHQDVKEMLGliDRTI--------IYDLILAVHQNQR 260
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
21-225 |
8.35e-14 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 73.34 E-value: 8.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 21 RPENLAQYIGQQHLLaagKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA----------------------- 76
Cdd:PRK05896 11 RPHNFKQIIGQELIK---KILVNAILNNKLtHAYIFSGPRGIGKTSIAKIFAKAINClnpkdgdccnscsvcesintnqs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 -DVERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGT--IFFIGATTENPSFELnsA 152
Cdd:PRK05896 88 vDIVELDAASnNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPkhVVFIFATTEFQKIPL--T 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504696103 153 LLSRARVYLLKSLTAEDIEKVLtqamDDKARgygGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVD 225
Cdd:PRK05896 166 IISRCQRYNFKKLNNSELQELL----KSIAK---KEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSE 231
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
53-156 |
1.17e-13 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 72.25 E-value: 1.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERI--SAVTSG-----VKEIREAIERARQNRNAgrrtILFVDEV---------- 115
Cdd:COG0464 194 LLLYGPPGTGKTLLARALAGELGLPLIEVdlSDLVSKyvgetEKNLREVFDKARGLAPC----VLFIDEAdalagkrgev 269
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 504696103 116 -HRFNKSQQDAFLPHIEDGT--IFFIGATteNPSFELNSALLSR 156
Cdd:COG0464 270 gDGVGRRVVNTLLTEMEELRsdVVVIAAT--NRPDLLDPALLRR 311
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
17-175 |
1.72e-13 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 72.50 E-value: 1.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 17 AARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYAN-----ADVERISAVTS---- 86
Cdd:PRK14971 8 ARKYRPSTFESVVGQEALTTT---LKNAIATNKLaHAYLFCGPRGVGKTTCARIFAKTINcqnltADGEACNECEScvaf 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 87 -----------------GVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTEN--- 144
Cdd:PRK14971 85 neqrsyniheldaasnnSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEppSYAIFILATTEKhki 164
|
170 180 190
....*....|....*....|....*....|..
gi 504696103 145 -PSfelnsaLLSRARVYLLKSLTAEDIEKVLT 175
Cdd:PRK14971 165 lPT------ILSRCQIFDFNRIQVADIVNHLQ 190
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
20-229 |
1.80e-13 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 70.93 E-value: 1.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 20 MRPENLAQYIGQQHLL--------AA---GKPLPraieagHLhsmILWGPPGTGKTTLAEVIARYANADVeRIsavTSGv 88
Cdd:PRK00080 19 LRPKSLDEFIGQEKVKenlkifieAAkkrGEALD------HV---LLYGPPGLGKTTLANIIANEMGVNI-RI---TSG- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 89 keirEAIERARQ------NRNAGrrTILFVDEVHRFNKSQQDAFLPHIEDGTI-------------------F-FIGATT 142
Cdd:PRK00080 85 ----PALEKPGDlaailtNLEEG--DVLFIDEIHRLSPVVEEILYPAMEDFRLdimigkgpaarsirldlppFtLIGATT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 143 EnpsfelnSALLS---RAR---VYLLKSLTAEDIEKVLTQAmddkARGYGgqdIVLPDETRRAIAELVNGDARRALNTLE 216
Cdd:PRK00080 159 R-------AGLLTsplRDRfgiVQRLEFYTVEELEKIVKRS----ARILG---VEIDEEGALEIARRSRGTPRIANRLLR 224
|
250
....*....|...
gi 504696103 217 MMADMAEVDDAGK 229
Cdd:PRK00080 225 RVRDFAQVKGDGV 237
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
34-159 |
2.54e-13 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 67.31 E-value: 2.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 34 LLAAGKPLPRaieaghlhSMILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNRNAgr 106
Cdd:cd19481 18 LRRYGLGLPK--------GILLYGPPGTGKTLLAKALAGELGLPLIVVKLssllskyVGESEKNLRKIFERARRLAPC-- 87
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 107 rtILFVDEVHRFNKSQQD------------AFLPHIEDGT----IFFIGATteNPSFELNSALLSRARV 159
Cdd:cd19481 88 --ILFIDEIDAIGRKRDSsgesgelrrvlnQLLTELDGVNsrskVLVIAAT--NRPDLLDPALLRPGRF 152
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
12-219 |
2.54e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 71.76 E-value: 2.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA-------------- 76
Cdd:PRK14950 2 TVQVLYRKWRSQTFAELVGQEHVVQT---LRNAIAEGRVaHAYLFTGPRGVGKTSTARILAKAVNCttndpkgrpcgtce 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 -----------DVERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGT--IFFIGATT 142
Cdd:PRK14950 79 mcraiaegsavDVIEMDAAShTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPphAIFILATT 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 143 EnpSFELNSALLSRARVYllksltaeDIEKVLTQAMDDKARGYGGQD-IVLPDETRRAIAELVNGDARRALNTLEMMA 219
Cdd:PRK14950 159 E--VHKVPATILSRCQRF--------DFHRHSVADMAAHLRKIAAAEgINLEPGALEAIARAATGSMRDAENLLQQLA 226
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
12-216 |
4.33e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 71.27 E-value: 4.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYANAD------------- 77
Cdd:PRK14957 2 SYQALARKYRPQSFAEVAGQQHALNS---LVHALETQKVHHAYLFtGTRGVGKTTLGRLLAKCLNCKtgvtaepcnkcen 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 ------------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTIF--FIGATTE 143
Cdd:PRK14957 79 cvainnnsfidlIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYvkFILATTD 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504696103 144 npSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRALNTLE 216
Cdd:PRK14957 159 --YHKIPVTILSRCIQLHLKHISQADIKDQLKIILAK-------ENINSDEQSLEYIAYHAKGSLRDALSLLD 222
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
13-223 |
1.16e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 69.07 E-value: 1.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 13 FQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLH-SMILWGPPGTGKTTLAEVIARYANA--------------- 76
Cdd:PRK14961 3 YQILARKWRPQYFRDIIGQKHIVTA---ISNGLSLGRIHhAWLLSGTRGVGKTTIARLLAKSLNCqngitsnpcrkciic 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 ---------DVERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGT--IFFIGATTEN 144
Cdd:PRK14961 80 keiekglclDLIEIDAASrTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPqhIKFILATTDV 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 145 PsfELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAE 223
Cdd:PRK14961 160 E--KIPKTILSRCLQFKLKIISEEKIFNFLKYILIK-------ESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGK 229
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
24-224 |
2.58e-12 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 67.32 E-value: 2.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 24 NLAQYIGQQHLLaagKPLPRAIEA-----GHLHSMILWGPPGTGKTTLAEVIARYANADVErisaVTSGvkeirEAIERA 98
Cdd:TIGR00635 2 LLAEFIGQEKVK---EQLQLFIEAakmrqEALDHLLLYGPPGLGKTTLAHIIANEMGVNLK----ITSG-----PALEKP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 99 RQNRNA----GRRTILFVDEVHRFNKSQQDAFLPHIEDGTI-------------------F-FIGATTEnpSFELNSALL 154
Cdd:TIGR00635 70 GDLAAIltnlEEGDVLFIDEIHRLSPAVEELLYPAMEDFRLdivigkgpsarsvrldlppFtLVGATTR--AGMLTSPLR 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504696103 155 SRARVYL-LKSLTAEDIEKVLTQamddkargYGGQ-DIVLPDETRRAIAELVNGDARRALNTLEMMADMAEV 224
Cdd:TIGR00635 148 DRFGIILrLEFYTVEELAEIVSR--------SAGLlNVEIEPEAALEIARRSRGTPRIANRLLRRVRDFAQV 211
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
51-165 |
1.22e-11 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 62.39 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 51 HSMILWGPPGTGKTTLAEVIARYANADVERISAV------------------------TSGVKEIREAIERARQNrnagR 106
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIdgedileevldqllliivggkkasGSGELRLRLALALARKL----K 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 107 RTILFVDEVHRFNKSQQDAFL----------PHIEDGTIFFIGATT-ENPSFELNSALLSRARVYLLKSL 165
Cdd:smart00382 79 PDVLILDEITSLLDAEQEALLllleelrlllLLKSEKNLTVILTTNdEKDLGPALLRRRFDRRIVLLLIL 148
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
12-223 |
1.83e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 66.00 E-value: 1.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHllaAGKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA-------------- 76
Cdd:PRK14953 2 MYIPFARKYRPKFFKEVIGQEI---VVRILKNAVKLQRVsHAYIFAGPRGTGKTTIARILAKVLNClnpqegepcgkcen 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 ----------DVERISAVTS-GVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED---GTIfFIGATT 142
Cdd:PRK14953 79 cveidkgsfpDLIEIDAASNrGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEpppRTI-FILCTT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 143 EnpSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRALNTLEMMADMA 222
Cdd:PRK14953 158 E--YDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNE-------EKIEYEEKALDLLAQASEGGMRDAASLLDQASTYG 228
|
.
gi 504696103 223 E 223
Cdd:PRK14953 229 E 229
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
13-216 |
2.08e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 65.92 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 13 FQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYANAD-------------- 77
Cdd:PRK14969 3 YQVLARKWRPKSFSELVGQEHVVRA---LTNALEQQRLHHAYLFtGTRGVGKTTLARILAKSLNCEtgvtatpcgvcsac 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 -----------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTEn 144
Cdd:PRK14969 80 leidsgrfvdlIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEppEHVKFILATTD- 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504696103 145 PSfELNSALLSRARVYLLK----SLTAEDIEKVLTQamddkargyggQDIVLPDETRRAIAELVNGDARRALNTLE 216
Cdd:PRK14969 159 PQ-KIPVTVLSRCLQFNLKqmppPLIVSHLQHILEQ-----------ENIPFDATALQLLARAAAGSMRDALSLLD 222
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
19-170 |
2.44e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 65.63 E-value: 2.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 19 RMRPENLAQYIGQQHLLAagkPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA--------------------- 76
Cdd:PRK14963 7 RARPITFDEVVGQEHVKE---VLLAALRQGRLgHAYLFSGPRGVGKTTTARLIAMAVNCsgedpkpcgecesclavrrga 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 --DVERISAVTS-GVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTEnPSfELNS 151
Cdd:PRK14963 84 hpDVLEIDAASNnSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEppEHVIFILATTE-PE-KMPP 161
|
170
....*....|....*....
gi 504696103 152 ALLSRARVYLLKSLTAEDI 170
Cdd:PRK14963 162 TILSRTQHFRFRRLTEEEI 180
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
21-121 |
2.91e-11 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 64.33 E-value: 2.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 21 RPENLAQYIGQQHLL--------AA---GKPLPraieagHLhsmILWGPPGTGKTTLAEVIARYANADVErisaVTSGVk 89
Cdd:COG2255 23 RPKRLDEYIGQEKVKenlkifieAAkkrGEALD------HV---LLYGPPGLGKTTLAHIIANEMGVNIR----ITSGP- 88
|
90 100 110
....*....|....*....|....*....|....*.
gi 504696103 90 eireAIERARQN----RNAGRRTILFVDEVHRFNKS 121
Cdd:COG2255 89 ----AIEKPGDLaailTNLEEGDVLFIDEIHRLSRV 120
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
15-215 |
8.95e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 63.93 E-value: 8.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 15 PLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYANAD----------VERISA 83
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQETVKAI---LSRAAQENRVAPAYLFsGTRGVGKTTIARIFAKALNCEtaptgepcntCEQCRK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 84 VTSG----VKEIREA----IERARQNRNA-------GRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTENPS 146
Cdd:PRK14959 82 VTQGmhvdVVEIDGAsnrgIDDAKRLKEAigyapmeGRYKVFIIDEAHMLTREAFNALLKTLEEppARVTFVLATTEPHK 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 147 FELnsALLSRARVYLLKSLTAEDIEKVLTQAMddkarGYGGQDivLPDETRRAIAELVNGDARRALNTL 215
Cdd:PRK14959 162 FPV--TIVSRCQHFTFTRLSEAGLEAHLTKVL-----GREGVD--YDPAAVRLIARRAAGSVRDSMSLL 221
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
14-163 |
1.73e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 62.66 E-value: 1.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 14 QPLAARMRPENLAQYIGQQhlLAAGKpLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYAN----------------- 75
Cdd:PRK14956 6 EVLSRKYRPQFFRDVIHQD--LAIGA-LQNALKSGKIgHAYIFFGPRGVGKTTIARILAKRLNcenpignepcnectscl 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 76 -------ADVERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTEnp 145
Cdd:PRK14956 83 eitkgisSDVLEIDAASnRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEppAHIVFILATTE-- 160
|
170
....*....|....*...
gi 504696103 146 SFELNSALLSRARVYLLK 163
Cdd:PRK14956 161 FHKIPETILSRCQDFIFK 178
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
25-156 |
4.21e-10 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 59.90 E-value: 4.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 25 LAQYIGQQHLLAAGKPLPRaieaghlhSMILWGPPGTGKTTLAEVIAR-------YANADveriSAVTS----GVKEIRE 93
Cdd:COG1223 18 IKELRRRENLRKFGLWPPR--------KILFYGPPGTGKTMLAEALAGelklpllTVRLD----SLIGSylgeTARNLRK 85
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 504696103 94 AIERARQnrnagRRTILFVDEVHRFNKS---QQD---------AFLPHIED--GTIFFIGATteNPSFELNSALLSR 156
Cdd:COG1223 86 LFDFARR-----APCVIFFDEFDAIAKDrgdQNDvgevkrvvnALLQELDGlpSGSVVIAAT--NHPELLDSALWRR 155
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
12-211 |
6.39e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 61.32 E-value: 6.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA-------------- 76
Cdd:PRK06647 2 SYRGTATKRRPRDFNSLEGQDFVVET---LKHSIESNKIaNAYIFSGPRGVGKTSSARAFARCLNCvngptpmpcgecss 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 ----------DVERIS-AVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTE 143
Cdd:PRK06647 79 cksidndnslDVIEIDgASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEppPYIVFIFATTE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 144 npSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRA 211
Cdd:PRK06647 159 --VHKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLE-------DQIKYEDEALKWIAYKSTGSVRDA 217
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
21-242 |
1.51e-09 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 59.93 E-value: 1.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 21 RPENLAQYIGQQHLLAAGKPLPRAIEAGHLH-SMILWGPPGTGKTTLAEVIARYANADV-------ERisavTSGVkeIR 92
Cdd:PRK04195 9 RPKTLSDVVGNEKAKEQLREWIESWLKGKPKkALLLYGPPGVGKTSLAHALANDYGWEVielnasdQR----TADV--IE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 93 EAIERARQNRN--AGRRTILFVDEVhrfnksqqDAFLPHIEDG---TIFFIGATTENP---------SFELNSaLLSRAR 158
Cdd:PRK04195 83 RVAGEAATSGSlfGARRKLILLDEV--------DGIHGNEDRGgarAILELIKKAKQPiiltandpyDPSLRE-LRNACL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 159 VYLLKSLTAEDIEKVLTQAMddKARGyggqdIVLPDETRRAIAELVNGDARRALNTLEMMADmaevddaGKRVLKPELLT 238
Cdd:PRK04195 154 MIEFKRLSTRSIVPVLKRIC--RKEG-----IECDDEALKEIAERSGGDLRSAINDLQAIAE-------GYGKLTLEDVK 219
|
....
gi 504696103 239 EIAG 242
Cdd:PRK04195 220 TLGR 223
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
13-181 |
3.28e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 58.63 E-value: 3.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 13 FQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYAN-----ADVE------- 79
Cdd:PRK06305 4 YQVSSRKYRPQTFSEILGQDAVVAV---LKNALRFNRAaHAYLFSGIRGTGKTTLARIFAKALNcqnptEDQEpcnqcas 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 80 --RISAVTS------------GVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTE 143
Cdd:PRK06305 81 ckEISSGTSldvleidgashrGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEppQHVKFFLATTE 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 504696103 144 NpsFELNSALLSRARVYLLKSLTAEDI-EKVLTQAMDDK 181
Cdd:PRK06305 161 I--HKIPGTILSRCQKMHLKRIPEETIiDKLALIAKQEG 197
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
12-228 |
4.82e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 57.98 E-value: 4.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLaagKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA-----DVERISAVT 85
Cdd:PRK14955 2 SYQVIARKYRPKKFADITAQEHIT---RTIQNSLRMGRVgHGYIFSGLRGVGKTTAARVFAKAVNCqrmidDADYLQEVT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 86 ----------------------------SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGT--I 135
Cdd:PRK14955 79 epcgecescrdfdagtslnisefdaasnNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPphA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 136 FFIGATTEnpSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDdkargygGQDIVLPDETRRAIAELVNGDARRALNTL 215
Cdd:PRK14955 159 IFIFATTE--LHKIPATIASRCQRFNFKRIPLEEIQQQLQGICE-------AEGISVDADALQLIGRKAQGSMRDAQSIL 229
|
250
....*....|....
gi 504696103 216 -EMMADMAEVDDAG 228
Cdd:PRK14955 230 dQVIAFSVESEGEG 243
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
19-225 |
5.73e-09 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 57.31 E-value: 5.73e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 19 RMRPENLAQYIgqqhLLAAGKPLPRAI-EAGHLHSMILWGP-PGTGKTTLAEVIARYANADVERISAVTSGVKEIR-EAI 95
Cdd:PHA02544 14 KYRPSTIDECI----LPAADKETFKSIvKKGRIPNMLLHSPsPGTGKTTVAKALCNEVGAEVLFVNGSDCRIDFVRnRLT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 96 ERARQNRNAGRRTILFVDEVHRfnksqqdAFLPHIEDGTIFFIGATTENPSF--------ELNSALLSRARVYLLKSLTA 167
Cdd:PHA02544 90 RFASTVSLTGGGKVIIIDEFDR-------LGLADAQRHLRSFMEAYSKNCSFiitannknGIIEPLRSRCRVIDFGVPTK 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504696103 168 EDIEKVLTQaMDDKARGYGGQDIVLPDetRRAIAELVNG---DARRALNTLEMMADMAEVD 225
Cdd:PHA02544 163 EEQIEMMKQ-MIVRCKGILEAEGVEVD--MKVLAALVKKnfpDFRRTINELQRYASTGKID 220
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
16-216 |
6.75e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 57.83 E-value: 6.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 16 LAARMRPENLAQYIGQQHLlaaGKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYAN------------------- 75
Cdd:PRK14965 6 LARKYRPQTFSDLTGQEHV---SRTLQNAIDTGRVaHAFLFTGARGVGKTSTARILAKALNceqgltaepcnvcppcvei 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 76 -----ADVERI-SAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFL-------PHIEdgtifFIGATT 142
Cdd:PRK14965 83 tegrsVDVFEIdGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLktleeppPHVK-----FIFATT 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504696103 143 EnpSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDKArgyggqdIVLPDETRRAIAELVNGDARRALNTLE 216
Cdd:PRK14965 158 E--PHKVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEG-------ISISDAALALVARKGDGSMRDSLSTLD 222
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
14-143 |
1.26e-08 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 57.20 E-value: 1.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 14 QPLAARMRPENLAQYIGQQHLLAagkPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANAD--------------- 77
Cdd:PRK14952 1 MALYRKYRPATFAEVVGQEHVTE---PLSSALDAGRInHAYLFSGPRGCGKTSSARILARSLNCAqgptatpcgvcescv 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 ------------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTE 143
Cdd:PRK14952 78 alapngpgsidvVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEppEHLIFIFATTE 157
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
14-178 |
2.67e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 55.81 E-value: 2.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 14 QPLAARMRPENLAQYIGQQhllAAGKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANAD--------------- 77
Cdd:PRK08451 2 QALALKYRPKHFDELIGQE---SVSKTLSLALDNNRLaHAYLFSGLRGSGKTSSARIFARALVCEqgpsstpcdtciqcq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 ----------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTIF--FIGATTEnp 145
Cdd:PRK08451 79 salenrhidiIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYvkFILATTD-- 156
|
170 180 190
....*....|....*....|....*....|...
gi 504696103 146 SFELNSALLSRARVYLLKSLTAEDIEKVLTQAM 178
Cdd:PRK08451 157 PLKLPATILSRTQHFRFKQIPQNSIISHLKTIL 189
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
21-287 |
3.84e-08 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 54.88 E-value: 3.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 21 RPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILWGPPGTGKTTLAEVIAR--YA----------NADVER-ISAVTSG 87
Cdd:PRK00440 12 RPRTLDEIVGQEEIVER---LKSYVKEKNMPHLLFAGPPGTGKTTAALALARelYGedwrenflelNASDERgIDVIRNK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 88 VKEireaIERARQNRNAGRRtILFVDEVHRFNKSQQDAFLPHIEdgtIFfigatTENPSFELnSA---------LLSRAR 158
Cdd:PRK00440 89 IKE----FARTAPVGGAPFK-IIFLDEADNLTSDAQQALRRTME---MY-----SQNTRFIL-SCnysskiidpIQSRCA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 159 VYLLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDAGK--RVL---K 233
Cdd:PRK00440 155 VFRFSPLKKEAVAERLRYIAEN-------EGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKEVTEEAvyKITgtaR 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504696103 234 PELLTEIAGER-SARFDNKGDRFY-----------DLISALHKSVRGSAPDAALywYARIITAGGD 287
Cdd:PRK00440 228 PEEIREMIELAlNGDFTEAREKLRdlmidyglsgeDIIKQIHREVWSLDIPEEL--KVELIDAIGE 291
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
12-275 |
1.13e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 53.97 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYANA----------DVER 80
Cdd:PRK14958 2 AHQVLARKWRPRCFQEVIGQAPVVRA---LSNALDQQYLHHAYLFtGTRGVGKTTISRILAKCLNCekgvsanpcnDCEN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 81 ISAVTSG---------------VKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTE 143
Cdd:PRK14958 79 CREIDEGrfpdlfevdaasrtkVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEppSHVKFILATTD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 144 NpsFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDkargyggQDIVLPDETRRAIAELVNGDARRALNTLE------- 216
Cdd:PRK14958 159 H--HKLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKE-------ENVEFENAALDLLARAANGSVRDALSLLDqsiaygn 229
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 217 ---MMADMAEVDDagkrVLKPELLTEI-------AGER----SARFDNKGDRFY----DLISALHK-SVRGSAPDAAL 275
Cdd:PRK14958 230 gkvLIADVKTMLG----TIEPLLLFDIlealaakAGDRllgcVTRLVEQGVDFSnalaDLLSLLHQiAIIQTVPEALI 303
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
13-212 |
1.35e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 54.11 E-value: 1.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 13 FQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYAN---AD----------- 77
Cdd:PRK12323 3 YQVLARKWRPRDFTTLVGQEHVVRA---LTHALEQQRLHHAYLFtGTRGVGKTTLSRILAKSLNctgADgeggitaqpcg 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 ----------------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIG 139
Cdd:PRK12323 80 qcracteidagrfvdyIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEppEHVKFIL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 504696103 140 ATTEnPSfELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDKARGYGGQDIvlpdetrRAIAELVNGDARRAL 212
Cdd:PRK12323 160 ATTD-PQ-KIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNAL-------RLLAQAAQGSMRDAL 223
|
|
| PspF |
COG1221 |
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ... |
50-154 |
1.52e-07 |
|
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms];
Pssm-ID: 440834 [Multi-domain] Cd Length: 835 Bit Score: 53.96 E-value: 1.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 50 LHSMILwGPPGTGKTTLAEVIARYA------NADVERIS-----------------------AVTSGVKEIREAIERArq 100
Cdd:COG1221 131 LHTLIL-GPTGVGKSFFAELMYEYAieigvlPEDAPFVVfncadyannpqllmsqlfgyvkgAFTGADKDKEGLIEKA-- 207
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 101 nrNAGrrtILFVDEVHRFNKSQQDAFLPHIEDGT--------------IFFIGATTENPsfelNSALL 154
Cdd:COG1221 208 --DGG---ILFLDEVHRLPPEGQEMLFTFMDKGIyrrlgetektrkanVRIIFATTEDP----ESSLL 266
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
21-287 |
2.13e-07 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 52.68 E-value: 2.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 21 RPENLAQYIGQQHllaAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADV---------------------- 78
Cdd:PRK12402 10 RPALLEDILGQDE---VVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPwennftefnvadffdqgkkylv 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 79 --ERISAVTSGVKEIREAI---------ERAR-QNRNAGRRTILFvDEVHRFNKSQQDAFLPHIE--DGTIFFIGATTeN 144
Cdd:PRK12402 87 edPRFAHFLGTDKRIRSSKidnfkhvlkEYASyRPLSADYKTILL-DNAEALREDAQQALRRIMEqySRTCRFIIATR-Q 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 145 PSfELNSALLSRARVYLLKSLTAEDIEKVLTQAMDdkargygGQDIVLPDETRRAIAELVNGDARRALNTLEMMA----- 219
Cdd:PRK12402 165 PS-KLIPPIRSRCLPLFFRAPTDDELVDVLESIAE-------AEGVDYDDDGLELIAYYAGGDLRKAILTLQTAAlaage 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 220 -DMAEVDDAGKRVLKPELLTEI-----AGE-RSAR------FDNKGDRFYDLISALHKSVRGSAPDAALywyARIITAGG 286
Cdd:PRK12402 237 iTMEAAYEALGDVGTDEVIESLldaaeAGDfTDARktlddlLIDEGLSGGEVLEELLRVARSRYRGDNL---ARLHRLAA 313
|
.
gi 504696103 287 D 287
Cdd:PRK12402 314 D 314
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
13-170 |
3.69e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 52.54 E-value: 3.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 13 FQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYANAD-------------- 77
Cdd:PRK07003 3 YQVLARKWRPKDFASLVGQEHVVRA---LTHALDGGRLHHAYLFtGTRGVGKTTLSRIFAKALNCEtgvtsqpcgvcrac 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 -----------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFL-------PHIEdgtifFIG 139
Cdd:PRK07003 80 reidegrfvdyVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLktleeppPHVK-----FIL 154
|
170 180 190
....*....|....*....|....*....|.
gi 504696103 140 ATTEnPSfELNSALLSRARVYLLKSLTAEDI 170
Cdd:PRK07003 155 ATTD-PQ-KIPVTVLSRCLQFNLKQMPAGHI 183
|
|
| PRK09111 |
PRK09111 |
DNA polymerase III subunits gamma and tau; Validated |
12-143 |
4.76e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236382 [Multi-domain] Cd Length: 598 Bit Score: 52.21 E-value: 4.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQhllAAGKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIAR---YANADV--------- 78
Cdd:PRK09111 10 PYRVLARKYRPQTFDDLIGQE---AMVRTLTNAFETGRIaQAFMLTGVRGVGKTTTARILARalnYEGPDGdggptidlc 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 79 ------------------ERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFL-------PHIEdg 133
Cdd:PRK09111 87 gvgehcqaimegrhvdvlEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLktleeppPHVK-- 164
|
170
....*....|
gi 504696103 134 tifFIGATTE 143
Cdd:PRK09111 165 ---FIFATTE 171
|
|
| RecA-like_VPS4-like |
cd19509 |
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ... |
52-161 |
5.03e-07 |
|
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410917 [Multi-domain] Cd Length: 163 Bit Score: 49.27 E-value: 5.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 52 SMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRR---TILFVDEV-----------HR 117
Cdd:cd19509 34 GILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKIVRALFALARElqpSIIFIDEIdsllsergsgeHE 113
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 504696103 118 FNKSQQDAFL------PHIEDGTIFFIGATteNPSFELNSALLSR--ARVYL 161
Cdd:cd19509 114 ASRRVKTEFLvqmdgvLNKPEDRVLVLGAT--NRPWELDEAFLRRfeKRIYI 163
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
12-229 |
7.16e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 51.48 E-value: 7.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHlhSMILWGPPGTGKTTLAEVIARYANA-----DVERISAVT- 85
Cdd:PRK14954 2 SYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGH--GYIFSGLRGVGKTTAARVFAKAVNCqrmidDPVYLQEVTe 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 86 ---------------------------SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIF 136
Cdd:PRK14954 80 pcgecescrdfdagtslnisefdaasnNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEppPHAI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 137 FIGATTEnpSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDdkargygGQDIVLPDETRRAIAELVNGDARRALNTLE 216
Cdd:PRK14954 160 FIFATTE--LHKIPATIASRCQRFNFKRIPLDEIQSQLQMICR-------AEGIQIDADALQLIARKAQGSMRDAQSILD 230
|
250
....*....|...
gi 504696103 217 MMADMAEVDDAGK 229
Cdd:PRK14954 231 QVIAFSVGSEAEK 243
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
51-114 |
7.23e-07 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 50.78 E-value: 7.23e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504696103 51 HSMILWGPPGTGKTTLAEVIARYANAD--VERISAVTS-----GVKEIREAIERARQNrnagRRTILFVDE 114
Cdd:COG1222 113 KGVLLYGPPGTGKTLLAKAVAGELGAPfiRVRGSELVSkyigeGARNVREVFELAREK----APSIIFIDE 179
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
52-156 |
8.79e-07 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 48.06 E-value: 8.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 52 SMILWGPPGTGKTTLAEVIA-RYANADVERI--SAVTSgVKEIREAIERARQN---------RNAGRRTILFVDEVHRFN 119
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAaALSNRPVFYVqlTRDTT-EEDLFGRRNIDPGGaswvdgplvRAAREGEIAVLDEINRAN 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 504696103 120 KSQQDAFLP-------HIEDGT---------IFFIGATTENPS--FELNSALLSR 156
Cdd:pfam07728 80 PDVLNSLLSllderrlLLPDGGelvkaapdgFRLIATMNPLDRglNELSPALRSR 134
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
15-216 |
1.08e-06 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 50.11 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 15 PLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILWGPPGTGKTTLAEVIAR------YANADVERISAVTSGV 88
Cdd:PLN03025 2 PWVEKYRPTKLDDIVGNEDAVSR---LQVIARDGNMPNLILSGPPGTGKTTSILALAHellgpnYKEAVLELNASDDRGI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 89 KEIREAIERARQNR---NAGRRTILFVDEVHRFNKSQQDAFLPHIE--DGTIFFigATTENPSFELNSALLSRARVYLLK 163
Cdd:PLN03025 79 DVVRNKIKMFAQKKvtlPPGRHKIVILDEADSMTSGAQQALRRTMEiySNTTRF--ALACNTSSKIIEPIQSRCAIVRFS 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 504696103 164 SLTAEDIEKVLTQAMddkargyGGQDIVLPDETRRAIAELVNGDARRALNTLE 216
Cdd:PLN03025 157 RLSDQEILGRLMKVV-------EAEKVPYVPEGLEAIIFTADGDMRQALNNLQ 202
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
54-115 |
1.18e-06 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 48.44 E-value: 1.18e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVERISAVT-----SGVKE--IREAIERARQNrnagRRTILFVDEV 115
Cdd:cd19503 38 LLHGPPGTGKTLLARAVANEAGANFLSISGPSivskyLGESEknLREIFEEARSH----APSIIFIDEI 102
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
21-216 |
1.35e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 50.64 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 21 RPENLAQYIGQQHLLaagKPLPRAIEAGHL-HSMILWGPPGTGKTTLAEVIARYANA----------------------- 76
Cdd:PRK05563 11 RPQTFEDVVGQEHIT---KTLKNAIKQGKIsHAYLFSGPRGTGKTSAAKIFAKAVNClnppdgepcneceickaitngsl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 -DVERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHR-----FNksqqdAFLPHIEDGT--IFFIGATTEnPSf 147
Cdd:PRK05563 88 mDVIEIDAASnNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMlstgaFN-----ALLKTLEEPPahVIFILATTE-PH- 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 148 ELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDKARGYggqdivlPDETRRAIAELVNGDARRALNTLE 216
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEY-------EDEALRLIARAAEGGMRDALSILD 222
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
54-115 |
1.46e-06 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 48.00 E-value: 1.46e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNrnagRRTILFVDEV 115
Cdd:cd19501 41 LLVGPPGTGKTLLAKAVAGEAGVPFFSISGsdfvemfVGVGASRVRDLFEQAKKN----APCIVFIDEI 105
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
16-219 |
1.46e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 50.55 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 16 LAARMRPENLAQYIGQQHLLaagKPLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIA----------------------- 71
Cdd:PRK14964 3 LALKYRPSSFKDLVGQDVLV---RILRNAFTLNKIPQSILLvGASGVGKTTCARIISlclncsngptsdpcgtchncisi 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 72 -RYANADVERISAVT-SGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIED--GTIFFIGATTENPSF 147
Cdd:PRK14964 80 kNSNHPDVIEIDAASnTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEpaPHVKFILATTEVKKI 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504696103 148 ELnsALLSRARVYLLKSLTaedIEKVLTQAMDDKARgyggQDIVLPDETRRAIAELVNGDARRALNTLEMMA 219
Cdd:PRK14964 160 PV--TIISRCQRFDLQKIP---TDKLVEHLVDIAKK----ENIEHDEESLKLIAENSSGSMRNALFLLEQAA 222
|
|
| RecA-like_PAN_like |
cd19502 |
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ... |
54-115 |
1.89e-06 |
|
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410910 [Multi-domain] Cd Length: 171 Bit Score: 47.72 E-value: 1.89e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNRNAgrrtILFVDEV 115
Cdd:cd19502 41 LLYGPPGTGKTLLAKAVANHTDATFIRVVGselvqkyIGEGARLVRELFEMAREKAPS----IIFIDEI 105
|
|
| RecA-like_VCP_r2 |
cd19529 |
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ... |
53-115 |
4.98e-06 |
|
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410937 [Multi-domain] Cd Length: 159 Bit Score: 46.33 E-value: 4.98e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADV------ERISA-VTSGVKEIREAIERARQnrnaGRRTILFVDEV 115
Cdd:cd19529 30 ILLYGPPGTGKTLLAKAVATESNANFisvkgpELLSKwVGESEKAIREIFRKARQ----VAPCVIFFDEI 95
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
11-156 |
4.99e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 48.81 E-value: 4.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 11 NAFQPLAARMRPENLAQYIGQQ-------HLLAAGKplpraIEAGHLHSmilwGPPGTGKTTLAEVIARYANA------- 76
Cdd:PRK14948 1 MAYEPLHHKYRPQRFDELVGQEaiattlkNALISNR-----IAPAYLFT----GPRGTGKTSSARILAKSLNClnsdkpt 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 77 -------------------DVERISAVT-SGVKEIREAIERAR----QnrnaGRRTILFVDEVHR-----FNksqqdAFL 127
Cdd:PRK14948 72 pepcgkcelcraiaagnalDVIEIDAASnTGVDNIRELIERAQfapvQ----ARWKVYVIDECHMlstaaFN-----ALL 142
|
170 180 190
....*....|....*....|....*....|.
gi 504696103 128 PHIED--GTIFFIGATTeNPSFELNSaLLSR 156
Cdd:PRK14948 143 KTLEEppPRVVFVLATT-DPQRVLPT-IISR 171
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
53-115 |
1.25e-05 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 45.47 E-value: 1.25e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA--VTSGV-----KEIREAIERARQNRNAgrrtILFVDEV 115
Cdd:cd19518 37 VLLHGPPGCGKTMLANAIAGELKVPFLKISAteIVSGVsgeseEKIRELFDQAISNAPC----IVFIDEI 102
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
53-262 |
1.28e-05 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 47.15 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIAR----------------YANADVER----------------ISAVTSGV--KEIREAIERA 98
Cdd:COG1474 54 VLIYGPTGTGKTAVAKYVLEeleeeaeergvdvrvvYVNCRQAStryrvlsrileelgsgEDIPSTGLstDELFDRLYEA 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 99 RQNRnaGRRTILFVDEVHRFNKSQQDAFL-------PHIEDGTIFFIGATTeNPSF--ELNSALLSRAR-------VYll 162
Cdd:COG1474 134 LDER--DGVLVVVLDEIDYLVDDEGDDLLyqllranEELEGARVGVIGISN-DLEFleNLDPRVKSSLGeeeivfpPY-- 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 163 kslTAEDIEKVLtqamDDKARgYGGQDIVLPDETRRAIAELV---NGDARRALNTLEMMADMAEvdDAGKRVLKPELLTE 239
Cdd:COG1474 209 ---DADELRDIL----EDRAE-LAFYDGVLSDEVIPLIAALAaqeHGDARKAIDLLRVAGEIAE--REGSDRVTEEHVRE 278
|
250 260
....*....|....*....|...
gi 504696103 240 iAGERSARfdnkgDRFYDLISAL 262
Cdd:COG1474 279 -AREKIER-----DRLLEVLRGL 295
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
54-115 |
1.41e-05 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 44.97 E-value: 1.41e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNRNAgrrtILFVDEV 115
Cdd:cd19511 31 LLYGPPGCGKTLLAKALASEAGLNFISVKGpelfskyVGESERAVREIFQKARQAAPC----IIFFDEI 95
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
28-81 |
1.92e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 46.31 E-value: 1.92e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504696103 28 YIGQQHL-------LAAGKPLpraieaghlhsmILWGPPGTGKTTLAEVIARYANADVERI 81
Cdd:COG0714 14 YVGQEELielvliaLLAGGHL------------LLEGVPGVGKTTLAKALARALGLPFIRI 62
|
|
| RecA-like_VPS4 |
cd19521 |
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ... |
53-161 |
2.55e-05 |
|
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410929 [Multi-domain] Cd Length: 170 Bit Score: 44.47 E-value: 2.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA---VTSGVKE----IREAIERARQNRNagrrTILFVDEVHRFNKSQQDA 125
Cdd:cd19521 43 ILLYGPPGTGKSYLAKAVATEANSTFFSVSSsdlVSKWMGEseklVKQLFAMARENKP----SIIFIDEVDSLCGTRGEG 118
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 504696103 126 -----------FLPHI------EDGtIFFIGATteNPSFELNSALLSR--ARVYL 161
Cdd:cd19521 119 eseasrrikteLLVQMngvgndSQG-VLVLGAT--NIPWQLDSAIRRRfeKRIYI 170
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
54-203 |
4.28e-05 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 45.82 E-value: 4.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 54 ILWGPPGTGKTTLAEVIA-RYANADVER-----------ISAVTSGVKEIREAIER-------ARQNRNagrrTILFVDE 114
Cdd:CHL00095 204 ILIGEPGVGKTAIAEGLAqRIVNRDVPDiledklvitldIGLLLAGTKYRGEFEERlkrifdeIQENNN----IILVIDE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 115 VHR-FNKSQQD-----AFL--PHIEDGTIFFIGATTEN---PSFELNSALLSRARVYLLKSLTAEDIEKVLTQAMDDKAR 183
Cdd:CHL00095 280 VHTlIGAGAAEgaidaANIlkPALARGELQCIGATTLDeyrKHIEKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEK 359
|
170 180
....*....|....*....|
gi 504696103 184 GYGgqdIVLPDETRRAIAEL 203
Cdd:CHL00095 360 HHN---LSISDKALEAAAKL 376
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
53-190 |
4.49e-05 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 46.05 E-value: 4.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADV------ERISA-VTSGVKEIREAIERARQNRNAgrrtILFVDEV--------HR 117
Cdd:TIGR01243 490 VLLFGPPGTGKTLLAKAVATESGANFiavrgpEILSKwVGESEKAIREIFRKARQAAPA----IIFFDEIdaiapargAR 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 118 FNKSQQDAFLPHI--------EDGTIFFIGATteNPSFELNSALLSRARVYLLKSLTAED------IEKVLTQAM---DD 180
Cdd:TIGR01243 566 FDTSVTDRIVNQLltemdgiqELSNVVVIAAT--NRPDILDPALLRPGRFDRLILVPPPDeearkeIFKIHTRSMplaED 643
|
170
....*....|....*...
gi 504696103 181 --------KARGYGGQDI 190
Cdd:TIGR01243 644 vdleelaeMTEGYTGADI 661
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
55-115 |
7.64e-05 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 44.82 E-value: 7.64e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 55 LWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNRNAgrrtILFVDEV 115
Cdd:PRK03992 170 LYGPPGTGKTLLAKAVAHETNATFIRVVGselvqkfIGEGARLVRELFELAREKAPS----IIFIDEI 233
|
|
| PTZ00454 |
PTZ00454 |
26S protease regulatory subunit 6B-like protein; Provisional |
54-115 |
8.63e-05 |
|
26S protease regulatory subunit 6B-like protein; Provisional
Pssm-ID: 240423 [Multi-domain] Cd Length: 398 Bit Score: 44.75 E-value: 8.63e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVerISAVTS---------GVKEIREAIERARQNRNAgrrtILFVDEV 115
Cdd:PTZ00454 183 LLYGPPGTGKTMLAKAVAHHTTATF--IRVVGSefvqkylgeGPRMVRDVFRLARENAPS----IIFIDEV 247
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
52-139 |
1.24e-04 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 41.56 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 52 SMILWGPPGTGKTTLAE-VIARYANADVERIS---AVTSGVKEIREAIERA-------------------RQNRNAGRRT 108
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRrLLEQLPEVRDSVVFvdlPSGTSPKDLLRALLRAlglplsgrlskeellaalqQLLLALAVAV 86
|
90 100 110
....*....|....*....|....*....|....*.
gi 504696103 109 ILFVDEVHRFnKSQQDAFLPHIEDG-----TIFFIG 139
Cdd:pfam13401 87 VLIIDEAQHL-SLEALEELRDLLNLsskllQLILVG 121
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
13-143 |
1.33e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 44.32 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 13 FQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYAN---AD----------- 77
Cdd:PRK14951 3 YLVLARKYRPRSFSEMVGQEHVVQA---LTNALTQQRLHHAYLFtGTRGVGKTTVSRILAKSLNcqgPDgqggitatpcg 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 ----------------VERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGT--IFFIG 139
Cdd:PRK14951 80 vcqacrdidsgrfvdyTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPeyLKFVL 159
|
....
gi 504696103 140 ATTE 143
Cdd:PRK14951 160 ATTD 163
|
|
| RecA-like_spastin |
cd19524 |
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ... |
53-161 |
1.40e-04 |
|
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410932 [Multi-domain] Cd Length: 164 Bit Score: 42.14 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRR---TILFVDEV-----------HRF 118
Cdd:cd19524 36 LLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARElqpSIIFIDEVdsllsersegeHEA 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 504696103 119 NKSQQDAFLPHIE------DGTIFFIGATteNPSFELNSALLSR--ARVYL 161
Cdd:cd19524 116 SRRLKTEFLIEFDgvqsngDDRVLVMGAT--NRPQELDDAVLRRftKRVYV 164
|
|
| RecA-like_CDC48_r2-like |
cd19528 |
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
53-159 |
2.04e-04 |
|
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 41.73 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA---VTSGVKE----IREAIERARqnrnAGRRTILFVDEVHRFNKSQ--- 122
Cdd:cd19528 30 VLFYGPPGCGKTLLAKAIANECQANFISVKGpelLTMWFGEseanVRDIFDKAR----AAAPCVLFFDELDSIAKARggn 105
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 504696103 123 -------QDAFLPHI---EDG-----TIFFIGATteNPSFELNSALLSRARV 159
Cdd:cd19528 106 igdaggaADRVINQIlteMDGmntkkNVFIIGAT--NRPDIIDPAILRPGRL 155
|
|
| RecA-like_Figl-1 |
cd19525 |
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ... |
53-161 |
2.42e-04 |
|
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410933 [Multi-domain] Cd Length: 186 Bit Score: 41.90 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNRNAgrrtILFVDEV---------- 115
Cdd:cd19525 58 ILLFGPPGTGKTLIGKCIASQSGATFFSISAssltskwVGEGEKMVRALFSVARCKQPA----VIFIDEIdsllsqrgeg 133
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 504696103 116 -HRFNKSQQDAFLPHIE------DGTIFFIGATteNPSFELNSALLSR--ARVYL 161
Cdd:cd19525 134 eHESSRRIKTEFLVQLDgattssEDRILVVGAT--NRPQEIDEAARRRlvKRLYI 186
|
|
| RecA-like_CDC48_r1-like |
cd19519 |
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ... |
53-134 |
2.80e-04 |
|
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410927 [Multi-domain] Cd Length: 166 Bit Score: 41.27 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADV-----ERISAVTSGVKE--IREAIERARQNRNAgrrtILFVDEVhrfnksqqDA 125
Cdd:cd19519 37 ILLYGPPGTGKTLIARAVANETGAFFflingPEIMSKLAGESEsnLRKAFEEAEKNAPA----IIFIDEI--------DA 104
|
....*....
gi 504696103 126 FLPHIEDGT 134
Cdd:cd19519 105 IAPKREKTH 113
|
|
| ATP-synt_ab |
pfam00006 |
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP ... |
57-112 |
3.08e-04 |
|
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.
Pssm-ID: 425417 [Multi-domain] Cd Length: 212 Bit Score: 41.96 E-value: 3.08e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 504696103 57 GPPGTGKTTLAEVIARYANADVERISAVtsGVK--EIREAIERARQNrNAGRRTILFV 112
Cdd:pfam00006 21 GGSGVGKTVLAGMIARQASADVVVYALI--GERgrEVREFIEELLGS-GALKRTVVVV 75
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
53-71 |
3.71e-04 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 41.84 E-value: 3.71e-04
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
53-223 |
4.28e-04 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 41.86 E-value: 4.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARyANADVERISA-VTSGVKEIREAIERARQNRNAGRRTI----------------LFVDEV 115
Cdd:COG2842 53 GVVYGESGVGKTTAAREYAN-RNPNVIYVTAsPSWTSKELLEELAEELGIPAPPGTIAdlrdrilerlagtgrlLIIDEA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 116 HRFNKsQQDAFLPHIEDGT---IFFIGatteNPSFElnsALLSR-ARVY-------LLKSLTAEDIEKVLTQAmddkarg 184
Cdd:COG2842 132 DHLKP-KALEELRDIHDETgvgVVLIG----MERLP---AKLKRyEQLYsrigfwvEFKPLSLEDVRALAEAW------- 196
|
170 180 190
....*....|....*....|....*....|....*....
gi 504696103 185 yggQDIVLPDEtRRAIAELVNGDARRALNTLEMMADMAE 223
Cdd:COG2842 197 ---GELTDPDL-LELLHRITRGNLRRLDRTLRLAARAAK 231
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
14-135 |
4.60e-04 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 42.66 E-value: 4.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 14 QPLAARMRPENLAQYIGQQHllaaGKplpRAIE--AGHLHSMILWGPPGTGKTTLAE----VIARYANADVERISAVTSG 87
Cdd:PRK09862 179 TDAVSRALQHDLSDVIGQEQ----GK---RGLEitAAGGHNLLLIGPPGTGKTMLASringLLPDLSNEEALESAAILSL 251
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504696103 88 VKEirEAIERARQNR--------------------------NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTI 135
Cdd:PRK09862 252 VNA--ESVQKQWRQRpfrsphhsasltamvgggaipgpgeiSLAHNGVLFLDELPEFERRTLDALREPIESGQI 323
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
25-67 |
4.92e-04 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 41.37 E-value: 4.92e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 504696103 25 LAQYIGQQHllaaGKplpRAIE---AGHlHSMILWGPPGTGKTTLA 67
Cdd:pfam01078 2 LADVKGQEQ----AK---RALEiaaAGG-HNLLMIGPPGSGKTMLA 39
|
|
| RecA-like_ATAD3-like |
cd19512 |
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ... |
48-127 |
4.98e-04 |
|
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410920 [Multi-domain] Cd Length: 150 Bit Score: 40.59 E-value: 4.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 48 GHLHSMILWGPPGTGKTTLAEVIARYANADVERISA------VTSGVKEIREAIERARQNRnagRRTILFVDEVhrfnks 121
Cdd:cd19512 20 GLYRNILFYGPPGTGKTLFAKKLALHSGMDYAIMTGgdvapmGREGVTAIHKVFDWANTSR---RGLLLFVDEA------ 90
|
....*.
gi 504696103 122 qqDAFL 127
Cdd:cd19512 91 --DAFL 94
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
53-134 |
5.24e-04 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 42.59 E-value: 5.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNRNAgrrtILFVDEVhrfnksqqDA 125
Cdd:TIGR01243 215 VLLYGPPGTGKTLLAKAVANEAGAYFISINGpeimskyYGESEERLREIFKEAEENAPS----IIFIDEI--------DA 282
|
....*....
gi 504696103 126 FLPHIEDGT 134
Cdd:TIGR01243 283 IAPKREEVT 291
|
|
| YifB |
COG0606 |
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ... |
24-68 |
7.83e-04 |
|
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440371 [Multi-domain] Cd Length: 502 Bit Score: 41.56 E-value: 7.83e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 504696103 24 NLAQYIGQQHllaaGKplpRAIE---AGHlHSMILWGPPGTGKTTLAE 68
Cdd:COG0606 190 DLADVKGQEQ----AK---RALEiaaAGG-HNLLMIGPPGSGKTMLAR 229
|
|
| PRK07940 |
PRK07940 |
DNA polymerase III subunit delta'; Validated |
29-176 |
9.13e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236134 [Multi-domain] Cd Length: 394 Bit Score: 41.44 E-value: 9.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 29 IGQQH----LLAAGKPLPRAIEAGHL---HSMILWGPPGTGKTTLA------------------------EVIARyANAD 77
Cdd:PRK07940 8 VGQEAvvaeLRAAARAARADVAAAGSgmtHAWLFTGPPGSGRSVAArafaaalqctdpdepgcgecracrTVLAG-THPD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 78 VERISA--VTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIE---DGTIFFIGAttenPSFE-LNS 151
Cdd:PRK07940 87 VRVVAPegLSIGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEeppPRTVWLLCA----PSPEdVLP 162
|
170 180
....*....|....*....|....*
gi 504696103 152 ALLSRARVYLLKSLTAEDIEKVLTQ 176
Cdd:PRK07940 163 TIRSRCRHVALRTPSVEAVAEVLVR 187
|
|
| PTZ00361 |
PTZ00361 |
26 proteosome regulatory subunit 4-like protein; Provisional |
54-115 |
9.15e-04 |
|
26 proteosome regulatory subunit 4-like protein; Provisional
Pssm-ID: 185575 [Multi-domain] Cd Length: 438 Bit Score: 41.30 E-value: 9.15e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVERIsaVTS---------GVKEIREAIERARQNRNAgrrtILFVDEV 115
Cdd:PTZ00361 221 ILYGPPGTGKTLLAKAVANETSATFLRV--VGSeliqkylgdGPKLVRELFRVAEENAPS----IVFIDEI 285
|
|
| RecA-like_ATAD1 |
cd19520 |
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ... |
53-156 |
9.60e-04 |
|
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410928 [Multi-domain] Cd Length: 166 Bit Score: 39.72 E-value: 9.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRR---TILFVDEVHRFNKSQQ------ 123
Cdd:cd19520 38 VLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGESQKLVAAVFSLASKlqpSIIFIDEIDSFLRQRSstdhea 117
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 504696103 124 ------------DAFLPHIEDgTIFFIGATteNPSFELNSALLSR 156
Cdd:cd19520 118 tammkaefmslwDGLSTDGNC-RVIVMGAT--NRPQDLDEAILRR 159
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
47-215 |
1.24e-03 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 40.98 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 47 AGHLHSMILWGPPGTGKTTLAEVIAR-YANADVERISAV--TSGVKEIREAIERARQNRNA------GRrtILFVDEVHR 117
Cdd:TIGR03922 309 AQTSNHMLFAGPPGTGKTTIARVVAKiYCGLGVLRKPLVreVSRADLIGQYIGESEAKTNEiidsalGG--VLFLDEAYT 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 118 -----------FNKSQQDAFLPHIED--GTIFFIGATTENPS---FELNSALLSR-ARVYLLKSLTAED---IEKVLTQA 177
Cdd:TIGR03922 387 lvetgygqkdpFGLEAIDTLLARMENdrDRLVVIGAGYRKDLdkfLEVNEGLRSRfTRVIEFPSYSPDElveIARRMATE 466
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 504696103 178 ----MDDKARgyggqDIVLPDETRRAIAEL--VNGDARRALNTL 215
Cdd:TIGR03922 467 rdsvLDDAAA-----DALLEAATTLAQDTTpdANGDLRRGLDIA 505
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
188-241 |
1.43e-03 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 36.74 E-value: 1.43e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 504696103 188 QDIVLPDETRRAIAELVNGDARRALNTLEMMAdmaevddAGKRVLKPELLTEIA 241
Cdd:cd18140 17 EGVKIDEEALEAIAEKSEGDMRKAINDLQAAA-------AGGGVITEEDVYEVA 63
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
54-74 |
1.49e-03 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 38.37 E-value: 1.49e-03
|
| RecA-like_NSF-SEC18_r1-like |
cd19504 |
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ... |
4-122 |
1.59e-03 |
|
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410912 [Multi-domain] Cd Length: 177 Bit Score: 39.40 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 4 LSLDFSDNAFQPLAARMRPENLAQYIGQQHLlaagkplpraieaghlHSMILWGPPGTGKTTLAEVIARYANADVERI-- 81
Cdd:cd19504 5 LDKEFSDIFRRAFASRVFPPEIVEQLGCKHV----------------KGILLYGPPGTGKTLMARQIGKMLNAREPKIvn 68
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 504696103 82 ------SAVTSGVKEIRE-----AIERARQNRNAGRRTILFvDEVHRFNKSQ 122
Cdd:cd19504 69 gpeilnKYVGESEANIRKlfadaEEEQRRLGANSGLHIIIF-DEIDAICKQR 119
|
|
| RecA-like_PEX1_r2 |
cd19526 |
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ... |
53-114 |
1.95e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410934 [Multi-domain] Cd Length: 158 Bit Score: 38.95 E-value: 1.95e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARqnrnAGRRTILFVDE 114
Cdd:cd19526 30 ILLYGPPGCGKTLLASAIASECGLNFISVKGpellnkyIGASEQNVRDLFSRAQ----SAKPCILFFDE 94
|
|
| ftsH |
CHL00176 |
cell division protein; Validated |
54-115 |
2.13e-03 |
|
cell division protein; Validated
Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 40.42 E-value: 2.13e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQNRNAgrrtILFVDEV 115
Cdd:CHL00176 220 LLVGPPGTGKTLLAKAIAGEAEVPFFSISGsefvemfVGVGAARVRDLFKKAKENSPC----IVFIDEI 284
|
|
| ExeA |
COG3267 |
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ... |
57-116 |
2.42e-03 |
|
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442498 [Multi-domain] Cd Length: 261 Bit Score: 39.39 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 57 GPPGTGKTTLAEVIARYANADVE----------------------RISAVTSGVKEIREAIERA-RQNRNAGRRTILFVD 113
Cdd:COG3267 50 GEVGTGKTTLLRRLLERLPDDVKvayipnpqlspaellraiadelGLEPKGASKADLLRQLQEFlLELAAAGRRVVLIID 129
|
...
gi 504696103 114 EVH 116
Cdd:COG3267 130 EAQ 132
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
12-176 |
2.96e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 39.85 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 12 AFQPLAARMRPENLAQYIGQQHLLAAgkpLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIARYANADvERISAVTSGV-- 88
Cdd:PRK07994 2 SYQVLARKWRPQTFAEVVGQEHVLTA---LANALDLGRLHHAYLFsGTRGVGKTTIARLLAKGLNCE-TGITATPCGEcd 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 89 --KEI----------------------REAIERARQNRNAGRRTILFVDEVH-----RFNksqqdAFL-------PHIEd 132
Cdd:PRK07994 78 ncREIeqgrfvdlieidaasrtkvedtRELLDNVQYAPARGRFKVYLIDEVHmlsrhSFN-----ALLktleeppEHVK- 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 504696103 133 gtifFIGATTEnPSfELNSALLSRARVYLLKSLTAEDI----EKVLTQ 176
Cdd:PRK07994 152 ----FLLATTD-PQ-KLPVTILSRCLQFHLKALDVEQIrqqlEHILQA 193
|
|
| hflB |
PRK10733 |
ATP-dependent zinc metalloprotease FtsH; |
53-115 |
3.16e-03 |
|
ATP-dependent zinc metalloprotease FtsH;
Pssm-ID: 182683 [Multi-domain] Cd Length: 644 Bit Score: 40.02 E-value: 3.16e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQnrnaGRRTILFVDEV 115
Cdd:PRK10733 188 VLMVGPPGTGKTLLAKAIAGEAKVPFFTISGsdfvemfVGVGASRVRDMFEQAKK----AAPCIIFIDEI 253
|
|
| fliI |
PRK07721 |
flagellar protein export ATPase FliI; |
34-97 |
4.35e-03 |
|
flagellar protein export ATPase FliI;
Pssm-ID: 181092 [Multi-domain] Cd Length: 438 Bit Score: 39.32 E-value: 4.35e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504696103 34 LLAAGKPLPRAIEAGhlhsmilwgpPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIER 97
Cdd:PRK07721 152 LLTVGKGQRVGIFAG----------SGVGKSTLMGMIARNTSADLNVIALIGERGREVREFIER 205
|
|
| RecA-like_PEX6_r2 |
cd19527 |
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ... |
53-158 |
4.48e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410935 [Multi-domain] Cd Length: 160 Bit Score: 37.88 E-value: 4.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARQnrnaGRRTILFVDEV-----HRFNK 120
Cdd:cd19527 29 ILLYGPPGTGKTLLAKAIATECSLNFLSVKGpelinmyIGESEANVREVFQKARD----AKPCVIFFDELdslapSRGNS 104
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 504696103 121 -----------SQQDAFLPHIEDGT--IFFIGATTEnPSFeLNSALLSRAR 158
Cdd:cd19527 105 gdsggvmdrvvSQLLAELDGMSSSGqdVFVIGATNR-PDL-LDPALLRPGR 153
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
19-72 |
5.23e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 39.20 E-value: 5.23e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 504696103 19 RMRPENLAQYIGQQHLLAagkPLPRAIEAGHLHSMILW-GPPGTGKTTLAEVIAR 72
Cdd:PRK07764 8 RYRPATFAEVIGQEHVTE---PLSTALDSGRINHAYLFsGPRGCGKTSSARILAR 59
|
|
| RecA-like_NVL_r2-like |
cd19530 |
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
53-133 |
6.29e-03 |
|
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410938 [Multi-domain] Cd Length: 161 Bit Score: 37.47 E-value: 6.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 53 MILWGPPGTGKTTLAEVIARYANADVERISA-------VTSGVKEIREAIERARqnrnAGRRTILFVDEVhrfnksqqDA 125
Cdd:cd19530 33 VLLYGPPGCGKTLLAKAVANESGANFISVKGpellnkyVGESERAVRQVFQRAR----ASAPCVIFFDEV--------DA 100
|
....*...
gi 504696103 126 FLPHIEDG 133
Cdd:cd19530 101 LVPKRGDG 108
|
|
| RecA-like_BCS1 |
cd19510 |
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ... |
54-159 |
6.69e-03 |
|
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410918 [Multi-domain] Cd Length: 153 Bit Score: 36.95 E-value: 6.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 54 ILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIReaieRARQNRNAGRRTILFVDEV------HRFNKSQQDAFL 127
Cdd:cd19510 27 LLYGPPGTGKSSFIAALAGELDYDICDLNLSEVVLTDDR----LNHLLNTAPKQSIILLEDIdaafesREHNKKNPSAYG 102
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 504696103 128 PHIE----------------DGTIFFIgaTTENPSfELNSALLSRARV 159
Cdd:cd19510 103 GLSRvtfsgllnaldgvassEERIVFM--TTNHIE-RLDPALIRPGRV 147
|
|
| SpoIIIAA |
COG3854 |
Stage III sporulation protein SpoIIIAA [Cell cycle control, cell division, chromosome ... |
29-88 |
7.27e-03 |
|
Stage III sporulation protein SpoIIIAA [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443063 Cd Length: 309 Bit Score: 38.21 E-value: 7.27e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 29 IGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGV 88
Cdd:COG3854 119 IAREVKGTADPILPYIISGGRIYNTLIISPPGCGKTTLLRDIARVLSDGLLGFPGKRVGV 178
|
|
| COG0645 |
COG0645 |
Predicted kinase, contains AAA domain [General function prediction only]; |
57-117 |
9.02e-03 |
|
Predicted kinase, contains AAA domain [General function prediction only];
Pssm-ID: 440410 [Multi-domain] Cd Length: 164 Bit Score: 36.81 E-value: 9.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504696103 57 GPPGTGKTTLAEVIARYANA-----DVER-------ISAVTSGV----KEIREAIERARQNRNAGRRTIL---FVDEVHR 117
Cdd:COG0645 6 GLPGSGKSTLARALAERLGAvrlrsDVVRkrlfgagLAPLERSPeataRTYARLLALARELLAAGRSVILdatFLRRAQR 85
|
|
| |
