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Conserved domains on  [gi|504697147|ref|WP_014884249|]
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MULTISPECIES: alpha,alpha-trehalase [Enterobacter]

Protein Classification

alpha,alpha-trehalase( domain architecture ID 10014167)

alpha,alpha-trehalase catalyzes the hydrolysis of alpha,alpha-trehalose to form alpha- and beta-D-glucose

CATH:  1.50.10.10
CAZY:  GH37
EC:  3.2.1.28
Gene Ontology:  GO:0005993|GO:0004555
PubMed:  4377836|31925485
SCOP:  4001563

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
treA PRK13271
alpha,alpha-trehalase TreA;
27-561 0e+00

alpha,alpha-trehalase TreA;


:

Pssm-ID: 237326  Cd Length: 569  Bit Score: 1076.87  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  27 SYADEQPAFQKNSPDILLGPLFNDVQSAKLFPDQKTFADAVPKSDPLMILADYRMQHTQSSFDLRHFVEMNFTLPAEGEK 106
Cdd:PRK13271  31 SVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEK 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 107 YVPPAGQSLREHIDDLWPVLTRTTDKASnKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKISDMVDNFA 186
Cdd:PRK13271 111 YVPPEGQSLREHIDGLWPVLTRSTENTE-KWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFA 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 187 WEIDTFGHIPNGNRSYYLSRSQPPFFSMMVELLATHDSD-ALKKYRPQMEKEYAYWMEGVDSLQPGQANQRVVKLDDGSV 265
Cdd:PRK13271 190 HEIDTWGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDaALKQYLPQMQKEYAYWMEGVENLQPGQQEKRVVKLQDGTL 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 266 LNRYWDDRDTPRPESWLDDVNTAKNNPNRPATEIYRDLRSAAASGWDFSSRWMDDPQKLGTIRTTSIVPVDLNALMFKME 345
Cdd:PRK13271 270 LNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTIRTTSIVPVDLNALMFKME 349

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 346 KLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQERADKVAAA 425
Cdd:PRK13271 350 KILARASKAAGDNAMANQYETLANARQKAIEKYLWNDKEGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRANKVAAA 429

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 426 TSARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEKYDVSTTGT 505
Cdd:PRK13271 430 TKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDVTWRFLTNVQHTYDREKKLVEKYDVSSTGT 509

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 504697147 506 GGGGGEYPLQDGFGWSNGVTLKMLDLVCPKEKPCDSVPENQPAANDEAAPVKAAAQ 561
Cdd:PRK13271 510 GGGGGEYPLQDGFGWTNGVTLKMLDLICPKEKPCDNVPATRPASKSATPPPKTKEA 565
 
Name Accession Description Interval E-value
treA PRK13271
alpha,alpha-trehalase TreA;
27-561 0e+00

alpha,alpha-trehalase TreA;


Pssm-ID: 237326  Cd Length: 569  Bit Score: 1076.87  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  27 SYADEQPAFQKNSPDILLGPLFNDVQSAKLFPDQKTFADAVPKSDPLMILADYRMQHTQSSFDLRHFVEMNFTLPAEGEK 106
Cdd:PRK13271  31 SVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEK 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 107 YVPPAGQSLREHIDDLWPVLTRTTDKASnKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKISDMVDNFA 186
Cdd:PRK13271 111 YVPPEGQSLREHIDGLWPVLTRSTENTE-KWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFA 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 187 WEIDTFGHIPNGNRSYYLSRSQPPFFSMMVELLATHDSD-ALKKYRPQMEKEYAYWMEGVDSLQPGQANQRVVKLDDGSV 265
Cdd:PRK13271 190 HEIDTWGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDaALKQYLPQMQKEYAYWMEGVENLQPGQQEKRVVKLQDGTL 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 266 LNRYWDDRDTPRPESWLDDVNTAKNNPNRPATEIYRDLRSAAASGWDFSSRWMDDPQKLGTIRTTSIVPVDLNALMFKME 345
Cdd:PRK13271 270 LNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTIRTTSIVPVDLNALMFKME 349

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 346 KLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQERADKVAAA 425
Cdd:PRK13271 350 KILARASKAAGDNAMANQYETLANARQKAIEKYLWNDKEGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRANKVAAA 429

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 426 TSARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEKYDVSTTGT 505
Cdd:PRK13271 430 TKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDVTWRFLTNVQHTYDREKKLVEKYDVSSTGT 509

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 504697147 506 GGGGGEYPLQDGFGWSNGVTLKMLDLVCPKEKPCDSVPENQPAANDEAAPVKAAAQ 561
Cdd:PRK13271 510 GGGGGEYPLQDGFGWTNGVTLKMLDLICPKEKPCDNVPATRPASKSATPPPKTKEA 565
TreA COG1626
Neutral trehalase [Carbohydrate transport and metabolism];
99-535 0e+00

Neutral trehalase [Carbohydrate transport and metabolism];


Pssm-ID: 441233  Cd Length: 438  Bit Score: 788.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  99 TLPAEGEKYVPPAGQSLREHIDDLWPVLTRTTDKAsNKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKI 178
Cdd:COG1626    2 ELPEPDESYVSDPGQTLREHIDALWPVLTRTPDEP-NEGSSLLPLPHPYVVPGGRFREIYYWDSYFTMLGLAESGRWDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 179 SDMVDNFAWEIDTFGHIPNGNRSYYLSRSQPPFFSMMVELLATHDSDA-LKKYRPQMEKEYAYWMEGVDSLQPGQANQRV 257
Cdd:COG1626   81 RDMVDNFAYLIDRYGHIPNGNRTYYLSRSQPPFFALMVELLAEHTGDEwLRRYLPQLEKEYAFWMDGADSLAPGQAYRRV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 258 VKLDDGSVLNRYWDDRDTPRPESWLDDVNTAKNNPNRPATEIYRDLRSAAASGWDFSSRWMDDPQKLGTIRTTSIVPVDL 337
Cdd:COG1626  161 VRLPDGTVLNRYWDDRDTPRPESYREDVETAKQSPERPAEEVYRDLRAGAESGWDFSSRWLADGKDLATIRTTDIVPVDL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 338 NALMFKMEKLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQE 417
Cdd:COG1626  241 NALLYHLETTLAKAYALAGDPAKAAEYRARAERRKEAINRYLWDEERGFYFDYDFVTGKQTAVLSAAAFYPLFAGIATPE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 418 RADKVAAATSARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEK 497
Cdd:COG1626  321 QAARVAETLEPQLLKPGGLVTTLVNSGQQWDAPNGWAPLQWMAVKGLRNYGYDDLAREIARRWLALVERVYERTGKLVEK 400

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 504697147 498 YDVSTTGTGGGGGEYPLQDGFGWSNGVTLKMLDLVCPK 535
Cdd:COG1626  401 YNVVDPSLEAGGGEYPLQDGFGWTNGVYLALLALLGEP 438
Trehalase pfam01204
Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a ...
 55-531 0e+00

Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.


Pssm-ID: 395961 [Multi-domain]  Cd Length: 509  Bit Score: 622.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147   55 KLFPDQKTFADAVPKSDPLMILADYRMQ------HTQSSFDLRHFVEMNFTLPA--------EGEKYVPP-----AGQSL 115
Cdd:pfam01204   1 KLFPDQKTFVDEARLNEPNRILRLIRAQfwraltRRIDGEDLRAFVEDYFDEPGdelprivpYDEKEQPEflqkiEDPDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  116 R---EHIDDLWPVLTRTTDKASNK---WDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKISDMVDNFAWEI 189
Cdd:pfam01204  81 RlwvEELNALWPALVRKINKKPGLlpeASSLLPLPNPFVVPGGRFRELYYWDSYFTILGLLESGMHDLAKGMVENFIYLI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  190 DTFGHIPNGNRSYYLSRSQPPFFSMMVELLATHDSD--ALKKYRPQMEKEYAYWMEgvdslqpGQANQRVVKLDDGSVLN 267
Cdd:pfam01204 161 ETYGHIPNGNRSYYLNRSQPPFLTDMVLLVYEKTEDdaLLRRYLAALKKEYAFWMA-------NPRLDPVTGLSDGYLLN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  268 RYWDDRDTPRPESWLDDVNTAKNNP-NRPATEIYRDLRSAAASGWDFSSRWMDDPQKLG---TIRTTSIVPVDLNALMFK 343
Cdd:pfam01204 234 RYGVPPETPRPESYLEDVEYAEKLPkERPKAYNYRDLKAGAESGWDFSSRWVREGHDTGylaEIRTTSLVPVDLNALLYK 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  344 MEKLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQERADKVA 423
Cdd:pfam01204 314 YEKDIAFFCDVLGDSETSAIWEERAEQRRLAIDKYLWNEEAGVWFDYDLKKRKQTNYFSATNFWPLWAGLASPDQAKMVA 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  424 AAT-----SARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEKY 498
Cdd:pfam01204 394 KVLpkleeSGLLVFPGGRPTSLLDSGQQWDYPNGWAPLQWLAVEGLQRYGYDELAERLAYRWLFTNTKAFVDEGKMVEKY 473

                         490       500       510
                  ....*....|....*....|....*....|....
gi 504697147  499 DVSTTGTG-GGGGEYPLQDGFGWSNGVTLKMLDL 531
Cdd:pfam01204 474 DVTRGGEYgGGGGEYVPQEGFGWTNGVYLYFLDL 507
 
Name Accession Description Interval E-value
treA PRK13271
alpha,alpha-trehalase TreA;
27-561 0e+00

alpha,alpha-trehalase TreA;


Pssm-ID: 237326  Cd Length: 569  Bit Score: 1076.87  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  27 SYADEQPAFQKNSPDILLGPLFNDVQSAKLFPDQKTFADAVPKSDPLMILADYRMQHTQSSFDLRHFVEMNFTLPAEGEK 106
Cdd:PRK13271  31 SVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEK 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 107 YVPPAGQSLREHIDDLWPVLTRTTDKASnKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKISDMVDNFA 186
Cdd:PRK13271 111 YVPPEGQSLREHIDGLWPVLTRSTENTE-KWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFA 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 187 WEIDTFGHIPNGNRSYYLSRSQPPFFSMMVELLATHDSD-ALKKYRPQMEKEYAYWMEGVDSLQPGQANQRVVKLDDGSV 265
Cdd:PRK13271 190 HEIDTWGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDaALKQYLPQMQKEYAYWMEGVENLQPGQQEKRVVKLQDGTL 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 266 LNRYWDDRDTPRPESWLDDVNTAKNNPNRPATEIYRDLRSAAASGWDFSSRWMDDPQKLGTIRTTSIVPVDLNALMFKME 345
Cdd:PRK13271 270 LNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTIRTTSIVPVDLNALMFKME 349

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 346 KLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQERADKVAAA 425
Cdd:PRK13271 350 KILARASKAAGDNAMANQYETLANARQKAIEKYLWNDKEGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRANKVAAA 429

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 426 TSARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEKYDVSTTGT 505
Cdd:PRK13271 430 TKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDVTWRFLTNVQHTYDREKKLVEKYDVSSTGT 509

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 504697147 506 GGGGGEYPLQDGFGWSNGVTLKMLDLVCPKEKPCDSVPENQPAANDEAAPVKAAAQ 561
Cdd:PRK13271 510 GGGGGEYPLQDGFGWTNGVTLKMLDLICPKEKPCDNVPATRPASKSATPPPKTKEA 565
TreA COG1626
Neutral trehalase [Carbohydrate transport and metabolism];
99-535 0e+00

Neutral trehalase [Carbohydrate transport and metabolism];


Pssm-ID: 441233  Cd Length: 438  Bit Score: 788.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  99 TLPAEGEKYVPPAGQSLREHIDDLWPVLTRTTDKAsNKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKI 178
Cdd:COG1626    2 ELPEPDESYVSDPGQTLREHIDALWPVLTRTPDEP-NEGSSLLPLPHPYVVPGGRFREIYYWDSYFTMLGLAESGRWDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 179 SDMVDNFAWEIDTFGHIPNGNRSYYLSRSQPPFFSMMVELLATHDSDA-LKKYRPQMEKEYAYWMEGVDSLQPGQANQRV 257
Cdd:COG1626   81 RDMVDNFAYLIDRYGHIPNGNRTYYLSRSQPPFFALMVELLAEHTGDEwLRRYLPQLEKEYAFWMDGADSLAPGQAYRRV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 258 VKLDDGSVLNRYWDDRDTPRPESWLDDVNTAKNNPNRPATEIYRDLRSAAASGWDFSSRWMDDPQKLGTIRTTSIVPVDL 337
Cdd:COG1626  161 VRLPDGTVLNRYWDDRDTPRPESYREDVETAKQSPERPAEEVYRDLRAGAESGWDFSSRWLADGKDLATIRTTDIVPVDL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 338 NALMFKMEKLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQE 417
Cdd:COG1626  241 NALLYHLETTLAKAYALAGDPAKAAEYRARAERRKEAINRYLWDEERGFYFDYDFVTGKQTAVLSAAAFYPLFAGIATPE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 418 RADKVAAATSARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEK 497
Cdd:COG1626  321 QAARVAETLEPQLLKPGGLVTTLVNSGQQWDAPNGWAPLQWMAVKGLRNYGYDDLAREIARRWLALVERVYERTGKLVEK 400

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 504697147 498 YDVSTTGTGGGGGEYPLQDGFGWSNGVTLKMLDLVCPK 535
Cdd:COG1626  401 YNVVDPSLEAGGGEYPLQDGFGWTNGVYLALLALLGEP 438
treA PRK13272
alpha,alpha-trehalase TreA;
33-535 0e+00

alpha,alpha-trehalase TreA;


Pssm-ID: 183936  Cd Length: 542  Bit Score: 674.32  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  33 PAFQKNSPDILLGPLFNDVQSAKLFPDQKTFADAVPKSDPLMILADYRMQHTQSSFDLRHFVEMNFTLPAEGEKYVPPAG 112
Cdd:PRK13272  38 PAPTPPTPDLAYPELFQAVQEGELFDDQKHFVDALPLRDPALINADYLAQHEHPGFDLRKFVDANFEESPPVQTDAIRQD 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 113 QSLREHIDDLWPVLTRTTDKASnKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKISDMVDNFAWEIDTF 192
Cdd:PRK13272 118 TALREHIDALWPKLVRSQEQVP-AHSSLLALPHPYVVPGGRFREVYYWDSYFTMLGLVKSGQTTLSRQMLDNFAYLIDTY 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 193 GHIPNGNRSYYLSRSQPPFFSMMVELLATHDSDAL-KKYRPQMEKEYAYWMEGVDSLQPGQANQRVVKLDDGSVLNRYWD 271
Cdd:PRK13272 197 GHIPNGNRTYYLSRSQPPFFSYMVELQAGVEGDAAyQRYLPQLQKEYAYWMQGSDDLQPGQAARHVVRLADGSLLNRYWD 276

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 272 DRDTPRPESWLDDVNTAKNNPNRPATEIYRDLRSAAASGWDFSSRWMDDPQKLGTIRTTSIVPVDLNALMFKMEKLLARA 351
Cdd:PRK13272 277 ERDTPRPEAWLHDTRTAAEAKDRPAAEVYRDLRAGAESGWDYSSRWLADGKTLASIRTTAIVPVDLNSLLYHLERTLAQA 356

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 352 SQDSGDSAAASQYEALATARQKAIENHLWNDkEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQERADKVAAATSARLL 431
Cdd:PRK13272 357 CASSGLAACSQDYAALAQQRKQAIDAHLWNP-AGYYADYDWQTRTLSEQVTAAALYPLFAGLASDDRAKRTADSVRAQLL 435

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 432 KPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEKYDVSTTGTGGGGGE 511
Cdd:PRK13272 436 RPGGLATTALKTGQQWDEPNGWAPLQWVAVDGLRRYGEDALARTIGERFLAQVQALFAREHKLVEKYGLDGNAAGGGGGE 515

                        490       500
                 ....*....|....*....|....
gi 504697147 512 YPLQDGFGWSNGVTLKMLDLVCPK 535
Cdd:PRK13272 516 YALQDGFGWTNGVTLMLLNLYPPG 539
treF PRK13270
alpha,alpha-trehalase TreF;
47-531 0e+00

alpha,alpha-trehalase TreF;


Pssm-ID: 183934  Cd Length: 549  Bit Score: 626.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  47 LFNDVQSAKLFPDQKTFADAVPKSDPLMILADYRMQHTQSSFDLRHFVEMNFTLPAEGE-KYVPPAGQSLREHIDDLWPV 125
Cdd:PRK13270  62 LFEHVQSSKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSsEYVSDPQNSLKEHIDQLWPV 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 126 LTRTTDKASnKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKISDMVDNFAWEIDTFGHIPNGNRSYYLS 205
Cdd:PRK13270 142 LTREPQDHI-PWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLS 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 206 RSQPPFFSMMVELLATHDSDALKKYRPQMEKEYAYWMEGVDSLQPGQANQRVVKLDDGSVLNRYWDDRDTPRPESWLDDV 285
Cdd:PRK13270 221 RSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDV 300

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 286 NTAKNNpNRPATEIYRDLRSAAASGWDFSSRWMDDPQKLGTIRTTSIVPVDLNALMFKMEKLLARASQDSGDSAAASQYE 365
Cdd:PRK13270 301 ETAKHS-GRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGEKETEALFR 379

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 366 ALATARQKAIENHLWNDKEGWYADYDLKskkvRNQL---TAAALFPLYVKAASQERADKVAAATSARLLKPGGITTTTIN 442
Cdd:PRK13270 380 QKASARRDAVNRYLWDDENGIYRDYDWR----REQLalfSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYE 455

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 443 SGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEKYDVSTTGTGGG-GGEYPLQDGFGWS 521
Cdd:PRK13270 456 TGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYQEHHKLIEKYHIAGGVPREGgGGEYPLQDGFGWT 535

                        490
                 ....*....|
gi 504697147 522 NGVTLKMLDL 531
Cdd:PRK13270 536 NGVVRRLIGL 545
Trehalase pfam01204
Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a ...
 55-531 0e+00

Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.


Pssm-ID: 395961 [Multi-domain]  Cd Length: 509  Bit Score: 622.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147   55 KLFPDQKTFADAVPKSDPLMILADYRMQ------HTQSSFDLRHFVEMNFTLPA--------EGEKYVPP-----AGQSL 115
Cdd:pfam01204   1 KLFPDQKTFVDEARLNEPNRILRLIRAQfwraltRRIDGEDLRAFVEDYFDEPGdelprivpYDEKEQPEflqkiEDPDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  116 R---EHIDDLWPVLTRTTDKASNK---WDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKISDMVDNFAWEI 189
Cdd:pfam01204  81 RlwvEELNALWPALVRKINKKPGLlpeASSLLPLPNPFVVPGGRFRELYYWDSYFTILGLLESGMHDLAKGMVENFIYLI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  190 DTFGHIPNGNRSYYLSRSQPPFFSMMVELLATHDSD--ALKKYRPQMEKEYAYWMEgvdslqpGQANQRVVKLDDGSVLN 267
Cdd:pfam01204 161 ETYGHIPNGNRSYYLNRSQPPFLTDMVLLVYEKTEDdaLLRRYLAALKKEYAFWMA-------NPRLDPVTGLSDGYLLN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  268 RYWDDRDTPRPESWLDDVNTAKNNP-NRPATEIYRDLRSAAASGWDFSSRWMDDPQKLG---TIRTTSIVPVDLNALMFK 343
Cdd:pfam01204 234 RYGVPPETPRPESYLEDVEYAEKLPkERPKAYNYRDLKAGAESGWDFSSRWVREGHDTGylaEIRTTSLVPVDLNALLYK 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  344 MEKLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALFPLYVKAASQERADKVA 423
Cdd:pfam01204 314 YEKDIAFFCDVLGDSETSAIWEERAEQRRLAIDKYLWNEEAGVWFDYDLKKRKQTNYFSATNFWPLWAGLASPDQAKMVA 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  424 AAT-----SARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEGLQNYGQNKVAMDVTWRFLKNVQHTYDREKKLVEKY 498
Cdd:pfam01204 394 KVLpkleeSGLLVFPGGRPTSLLDSGQQWDYPNGWAPLQWLAVEGLQRYGYDELAERLAYRWLFTNTKAFVDEGKMVEKY 473

                         490       500       510
                  ....*....|....*....|....*....|....
gi 504697147  499 DVSTTGTG-GGGGEYPLQDGFGWSNGVTLKMLDL 531
Cdd:pfam01204 474 DVTRGGEYgGGGGEYVPQEGFGWTNGVYLYFLDL 507
PLN02567 PLN02567
alpha,alpha-trehalase
 40-530 4.14e-129

alpha,alpha-trehalase


Pssm-ID: 215307  Cd Length: 554  Bit Score: 388.62  E-value: 4.14e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147  40 PDILLGPLFNDVQSAKL-------FPDQKTFAD---AVPKSDPLMILADY-RMQHTQSSF--DLRHFVEMNFTLPAEG-E 105
Cdd:PLN02567   3 PTTPLLTFLVRVQSTALasfggedTFDPKLYVDlplKFSLSETEKAFDALpRSNINGSVPveELEEFVAEYFDVAGSDlL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 106 KYVPP-------------AGQSLRE---HIDDLWPVLTR--TTDKASNKW-DSLLPLPKPYVVPGGRFREVYYWDSYFTM 166
Cdd:PLN02567  83 PYTPPdfvpeppgflpkvENPEAREwalKVHSLWKNLARkvSDSVEERPDrHTLLPLPNPVVVPGSRFREVYYWDSYWVI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 167 LGLAESGHWDKISDMVDNFAWEIDTFGHIPNGNRSYYLSRSQPPFFSMMVELL--ATHDSDALKKYRPQMEKEYAYWMEG 244
Cdd:PLN02567 163 RGLLASKMYETAKGVVENLLYLVDTYGFVPNGARAYYTNRSQPPLLSAMVLAVyaATKDVELVRRALPALLKEHAFWTSG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 245 VdslqpgqanqRVVKLDDGS----VLNRYWDDRDTPRPESWLDDVNTAKN-NPNRPATEIYRDLRSAAASGWDFSSRWMD 319
Cdd:PLN02567 243 R----------HTVTIRDANgvvhVLSRYYAMWDKPRPESSRIDKEVASKfSSSSEKQQLYRDIASAAESGWDFSSRWMR 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 320 DPQKLGTIRTTSIVPVDLNALMFKMEKLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWYADY--------D 391
Cdd:PLN02567 313 DGSNLTTLRTTSILPVDLNAFLLKMELDIAFFAKLLGDKATAERFLKAAKARKRAINAVLWNEEMGQWLDYwlppngatC 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 392 LKSKKVR----NQLTAAALF-PLYVKAAS--QERADKVAAA-TSARLLKPGGITTTTINSGQQWDAPNGWAPLQWVATEG 463
Cdd:PLN02567 393 QESYTWDaenqNTNVYASNFvPLWCGVVPpgDAKVEKVVESlKSSGLVLPAGIATSLRNTGQQWDFPNAWAPLQHMIVEG 472

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 464 LQNYG---QNKVAMDVTWRFLKNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWSNGVTLKMLD 530
Cdd:PLN02567 473 LAASGskeGKALAEDIARRWLRSNYVAYKKTGAMHEKYDARYCGEVGGGGEYIPQTGFGWSNGVVLSLLE 542
GDB1 COG3408
Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism];
154-481 7.15e-15

Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism];


Pssm-ID: 442634 [Multi-domain]  Cd Length: 353  Bit Score: 76.07  E-value: 7.15e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 154 FREVYYWDSYFTMLGLAeSGHWDKISDMVDNFAWEIDTFGHIPN----GNRSYYLSRSQPPFFSMMVE--LLATHDSDAL 227
Cdd:COG3408   29 FSTDWGRDTLIALPGLL-LLDPELARGILRTLARYQEEPGKIPHevrdGEEPYYGTVDATPWFIIALGeyYRWTGDLAFL 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 228 KKYRPQMEKEYAYWMEGvdslqpgqanqrvvklddgsvlnrywdDRDTprpeswlddvntaknnpnrpateiyRDLRSAA 307
Cdd:COG3408  108 RELLPALEAALDWILRG---------------------------DRDG-------------------------DGLLEYG 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 308 ASGWDfSSRWMDDPQKLGTIRttSIVPVDLNALMFKMEKLLARASQDSGDSAAASQYEALATARQKAIENHLWNDKEGWY 387
Cdd:COG3408  136 RSGLD-NQTWMDSKVDSVTPR--SGALVEVQALWYNALRALAELARALGDPELAARWRELAERLKESFNERFWNEELGYL 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 388 ADYDLKSKKVRNQLTAAALF--PLYVKAASQERADKVAAAT-SARLLKPGGITTTTINSGqQWDAP---NG--WAPLQWV 459
Cdd:COG3408  213 ADALDGDGRPDDSIRPNQLFahALPTGILDPERARAVLRRLvSPELLTPWGLRTLSPGDP-AYNPMayhNGsvWPWLNGL 291

                        330       340
                 ....*....|....*....|..
gi 504697147 460 ATEGLQNYGQNKVAMDVTWRFL 481
Cdd:COG3408  292 YAEGLLRYGFREEARRLLEGLL 313
PRK10137 PRK10137
alpha-glucosidase; Provisional
 299-485 4.42e-03

alpha-glucosidase; Provisional


Pssm-ID: 236653  Cd Length: 786  Bit Score: 40.14  E-value: 4.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 299 IYRD-LRSAAASGW---DFSSRWMDDPQKLGTIRTTSIV--PVDLNALMFKMEKLLARASQDSGDSAAASQYEALATARQ 372
Cdd:PRK10137 536 IDKEqLDKYVANGGkrsDWTVKFAENRSQDGTLLGYSLLqeSVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLA 615

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504697147 373 KAIENHLWNDKEGWYADYDLKSKKVRNQLTAAALF----------PLYVKAASQERADKVAAAtsarLLKPGGITT---- 438
Cdd:PRK10137 616 DYINTCMFDETTGFYYDVRIEDKPLANGCAGKPIVergkgpegwsPLFNGAATQANADAVVKV----MLDPKEFNTfvpl 691

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 504697147 439 -TTINSGQQWDAPNGWAPLQWV-----ATEGLQNYGQNKVAMDVTWRFLKNVQ 485
Cdd:PRK10137 692 gTAALTNPAFGADIYWRGRVWVdqfyfGLKGMERYGYRDDALKLADTFFRHAK 744
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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