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Conserved domains on  [gi|504821067|ref|WP_015008169|]
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class I SAM-dependent methyltransferase [Sinorhizobium meliloti]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10789277)

class I SAM-dependent methyltransferase is an enzyme that uses S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyl transfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:1904047
PubMed:  12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 24-140 2.58e-31

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


:

Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 113.17  E-value: 2.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  24 LAPKFIDFAGVADGEKVLDVGCGTGSLTFALADAARlkEIAAIDYSPVFVEEATRRNT--NPRIKIREADACALPFEDRT 101
Cdd:COG2226   10 GREALLAALGLRPGARVLDLGCGTGRLALALAERGA--RVTGVDISPEMLELARERAAeaGLNVEFVVGDAEDLPFPDGS 87

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 504821067 102 FDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVAAAVWD 140
Cdd:COG2226   88 FDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFS 126
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 24-140 2.58e-31

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 113.17  E-value: 2.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  24 LAPKFIDFAGVADGEKVLDVGCGTGSLTFALADAARlkEIAAIDYSPVFVEEATRRNT--NPRIKIREADACALPFEDRT 101
Cdd:COG2226   10 GREALLAALGLRPGARVLDLGCGTGRLALALAERGA--RVTGVDISPEMLELARERAAeaGLNVEFVVGDAEDLPFPDGS 87

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 504821067 102 FDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVAAAVWD 140
Cdd:COG2226   88 FDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFS 126
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 40-132 5.34e-28

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 103.03  E-value: 5.34e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   40 VLDVGCGTGSLTFALADAARlKEIAAIDYSPVFVEEATRRNT--NPRIKIREADACALPFEDRTFDRAFALLVLHFV--P 115
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGG-ARVTGVDLSPEMLERARERAAeaGLNVEFVQGDAEDLPFPDGSFDLVVSSGVLHHLpdP 79

                          90
                  ....*....|....*..
gi 504821067  116 EAGQAVAEMRRVVRPGG 132
Cdd:pfam13649  80 DLEAALREIARVLKPGG 96
PRK08317 PRK08317
hypothetical protein; Provisional
 31-140 5.01e-21

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 88.84  E-value: 5.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  31 FAGVADGEKVLDVGCGTGSLTFALADA----ARLkeiAAIDYSPVFVEEATRR--NTNPRIKIREADACALPFEDRTFDR 104
Cdd:PRK08317  14 LLAVQPGDRVLDVGCGPGNDARELARRvgpeGRV---VGIDRSEAMLALAKERaaGLGPNVEFVRGDADGLPFPDGSFDA 90

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 504821067 105 AFALLVLHFVPEAGQAVAEMRRVVRPGG--VVAAAVWD 140
Cdd:PRK08317  91 VRSDRVLQHLEDPARALAEIARVLRPGGrvVVLDTDWD 128
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 27-135 3.37e-18

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 80.77  E-value: 3.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   27 KFIDFAGVADGEKVLDVGCGTGSLTFALAD-AARLKEIAAIDYSPVFVEEATRRNTNP-RIKIREADACALPFEDRTFDR 104
Cdd:TIGR01934  30 RAVKLIGVFKGQKVLDVACGTGDLAIELAKsAPDRGKVTGVDFSSEMLEVAKKKSELPlNIEFIQADAEALPFEDNSFDA 109

                          90       100       110
                  ....*....|....*....|....*....|.
gi 504821067  105 AFALLVLHFVPEAGQAVAEMRRVVRPGGVVA 135
Cdd:TIGR01934 110 VTIAFGLRNVTDIQKALREMYRVLKPGGRLV 140
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 39-139 2.66e-15

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 69.77  E-value: 2.66e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  39 KVLDVGCGTGSLTFALADAARlKEIAAIDYSPVFVEEATRRNTN---PRIKIREADACALPF-EDRTFDRAFALLVLHFV 114
Cdd:cd02440    1 RVLDLGCGTGALALALASGPG-ARVTGVDISPVALELARKAAAAllaDNVEVLKGDAEELPPeADESFDVIISDPPLHHL 79

                         90       100
                 ....*....|....*....|....*.
gi 504821067 115 PEAGQAV-AEMRRVVRPGGVVAAAVW 139
Cdd:cd02440   80 VEDLARFlEEARRLLKPGGVLVLTLV 105
rADc smart00650
Ribosomal RNA adenine dimethylases;
27-107 5.30e-08

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 51.36  E-value: 5.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067    27 KFIDFAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEATRR-NTNPRIKIREADACALPFEDRTFDRA 105
Cdd:smart00650   4 KIVRAANLRPGDTVLEIGPGKGALTEELLERA--KRVTAIEIDPRLAPRLREKfAAADNLTVIHGDALKFDLPKLQPYKV 81


                   ..
gi 504821067   106 FA 107
Cdd:smart00650  82 VG 83
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 24-140 2.58e-31

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 113.17  E-value: 2.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  24 LAPKFIDFAGVADGEKVLDVGCGTGSLTFALADAARlkEIAAIDYSPVFVEEATRRNT--NPRIKIREADACALPFEDRT 101
Cdd:COG2226   10 GREALLAALGLRPGARVLDLGCGTGRLALALAERGA--RVTGVDISPEMLELARERAAeaGLNVEFVVGDAEDLPFPDGS 87

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 504821067 102 FDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVAAAVWD 140
Cdd:COG2226   88 FDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFS 126
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 40-132 5.34e-28

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 103.03  E-value: 5.34e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   40 VLDVGCGTGSLTFALADAARlKEIAAIDYSPVFVEEATRRNT--NPRIKIREADACALPFEDRTFDRAFALLVLHFV--P 115
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGG-ARVTGVDLSPEMLERARERAAeaGLNVEFVQGDAEDLPFPDGSFDLVVSSGVLHHLpdP 79

                          90
                  ....*....|....*..
gi 504821067  116 EAGQAVAEMRRVVRPGG 132
Cdd:pfam13649  80 DLEAALREIARVLKPGG 96
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 41-135 6.91e-28

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 102.74  E-value: 6.91e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   41 LDVGCGTGSLTFALADAARlkEIAAIDYSPVFVEEATRRNTNPRIKIREADACALPFEDRTFDRAFALLVLHFVPEAGQA 120
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGA--RVTGVDISPEMLELAREKAPREGLTFVVGDAEDLPFPDNSFDLVLSSEVLHHVEDPERA 78

                          90
                  ....*....|....*
gi 504821067  121 VAEMRRVVRPGGVVA 135
Cdd:pfam08241  79 LREIARVLKPGGILI 93
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 19-138 1.63e-25

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 97.40  E-value: 1.63e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  19 RWSRKLApKFIDfAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEATRRNTNPRIKIREADACALPFE 98
Cdd:COG2227    9 FWDRRLA-ALLA-RLLPAGGRVLDVGCGTGRLALALARRG--ADVTGVDISPEALEIARERAAELNVDFVQGDLEDLPLE 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 504821067  99 DRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVAAAV 138
Cdd:COG2227   85 DGSFDLVICSEVLEHLPDPAALLRELARLLKPGGLLLLST 124
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
37-138 7.15e-22

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 87.19  E-value: 7.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  37 GEKVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEAtrRNTNPRIKIREADACALPFEdRTFDRAFALLVLHFVPE 116
Cdd:COG4106    2 PRRVLDLGCGTGRLTALLAERFPGARVTGVDLSPEMLARA--RARLPNVRFVVADLRDLDPP-EPFDLVVSNAALHWLPD 78

                         90       100
                 ....*....|....*....|..
gi 504821067 117 AGQAVAEMRRVVRPGGVVAAAV 138
Cdd:COG4106   79 HAALLARLAAALAPGGVLAVQV 100
PRK08317 PRK08317
hypothetical protein; Provisional
 31-140 5.01e-21

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 88.84  E-value: 5.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  31 FAGVADGEKVLDVGCGTGSLTFALADA----ARLkeiAAIDYSPVFVEEATRR--NTNPRIKIREADACALPFEDRTFDR 104
Cdd:PRK08317  14 LLAVQPGDRVLDVGCGPGNDARELARRvgpeGRV---VGIDRSEAMLALAKERaaGLGPNVEFVRGDADGLPFPDGSFDA 90

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 504821067 105 AFALLVLHFVPEAGQAVAEMRRVVRPGG--VVAAAVWD 140
Cdd:PRK08317  91 VRSDRVLQHLEDPARALAEIARVLRPGGrvVVLDTDWD 128
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 27-135 1.96e-20

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 87.13  E-value: 1.96e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  27 KFIDFAGVADGEKVLDVGCGTGSLTFALADAARLK-EIAAIDYSP----VFVEEATRRNTNPRIKIREADACALPFEDRT 101
Cdd:PRK00216  42 KTIKWLGVRPGDKVLDLACGTGDLAIALAKAVGKTgEVVGLDFSEgmlaVGREKLRDLGLSGNVEFVQGDAEALPFPDNS 121

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 504821067 102 FDR---AFAllvLHFVPEAGQAVAEMRRVVRPGGVVA 135
Cdd:PRK00216 122 FDAvtiAFG---LRNVPDIDKALREMYRVLKPGGRLV 155
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
9-141 7.18e-20

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 84.28  E-value: 7.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   9 DAAGYEQLMGRWSRKLAPKFIDFAGVADGEKVLDVGCGTGSLTFALADAARlkEIAAIDYSPVFVEEAtrRNTNPRIKIR 88
Cdd:COG4976   19 DAALVEDLGYEAPALLAEELLARLPPGPFGRVLDLGCGTGLLGEALRPRGY--RLTGVDLSEEMLAKA--REKGVYDRLL 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 504821067  89 EADACALPFEDRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVAAAVWDH 141
Cdd:COG4976   95 VADLADLAEPDGRFDLIVAADVLTYLGDLAAVFAGVARALKPGGLFIFSVEDA 147
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 27-135 3.37e-18

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 80.77  E-value: 3.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   27 KFIDFAGVADGEKVLDVGCGTGSLTFALAD-AARLKEIAAIDYSPVFVEEATRRNTNP-RIKIREADACALPFEDRTFDR 104
Cdd:TIGR01934  30 RAVKLIGVFKGQKVLDVACGTGDLAIELAKsAPDRGKVTGVDFSSEMLEVAKKKSELPlNIEFIQADAEALPFEDNSFDA 109

                          90       100       110
                  ....*....|....*....|....*....|.
gi 504821067  105 AFALLVLHFVPEAGQAVAEMRRVVRPGGVVA 135
Cdd:TIGR01934 110 VTIAFGLRNVTDIQKALREMYRVLKPGGRLV 140
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 19-172 3.56e-18

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 79.96  E-value: 3.56e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  19 RWSRKLAP----KFIDFAGVADGEKVLDVGCGTGSLTFALADAARLKEIaAIDYSPVFVEEATRRNTN---PRIKIREAD 91
Cdd:COG0500    5 YYSDELLPglaaLLALLERLPKGGRVLDLGCGTGRNLLALAARFGGRVI-GIDLSPEAIALARARAAKaglGNVEFLVAD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  92 ACAL-PFEDRTFDRAFALLVLHFVPEA--GQAVAEMRRVVRPGGVVAAAVWDHLGGMPGMRMMVDTVAALSEGGRRLRAR 168
Cdd:COG0500   84 LAELdPLPAESFDLVVAFGVLHHLPPEerEALLRELARALKPGGVLLLSASDAAAALSLARLLLLATASLLELLLLLRLL 163


                 ....
gi 504821067 169 YCFQ 172
Cdd:COG0500  164 ALEL 167
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 41-134 2.15e-16

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 72.40  E-value: 2.15e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   41 LDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEATRR------NTNPRIKIREADACALPFEdrTFDRAFALLVLHFV 114
Cdd:pfam08242   1 LEIGCGTGTLLRALLEALPGLEYTGLDISPAALEAARERlaalglLNAVRVELFQLDLGELDPG--SFDVVVASNVLHHL 78

                          90       100
                  ....*....|....*....|
gi 504821067  115 PEAGQAVAEMRRVVRPGGVV 134
Cdd:pfam08242  79 ADPRAVLRNIRRLLKPGGVL 98
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
4-134 7.93e-16

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 74.40  E-value: 7.93e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067    4 SFNVHDaagyeqlmgRWSRKLapkfIDFAGVADGEKVLDVGCGTGSLTFALADAARLK-EIAAIDYSPVFVEEATRRNTN 82
Cdd:pfam01209  23 SFGIHR---------LWKDFT----MKCMGVKRGNKFLDVAGGTGDWTFGLSDSAGSSgKVVGLDINENMLKEGEKKAKE 89

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 504821067   83 P---RIKIREADACALPFEDRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVV 134
Cdd:pfam01209  90 EgkyNIEFLQGNAEELPFEDDSFDIVTISFGLRNFPDYLKVLKEAFRVLKPGGRV 144
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 28-135 1.68e-15

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 71.88  E-value: 1.68e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  28 FIDFAGVADGEKVLDVGCGTGSLTFALADAARLKeIAAIDYSPVFVEEATRR----NTNPRIKIREADACALPFeDRTFD 103
Cdd:COG2230   43 ILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVR-VTGVTLSPEQLEYARERaaeaGLADRVEVRLADYRDLPA-DGQFD 120

                         90       100       110
                 ....*....|....*....|....*....|....
gi 504821067 104 RAFALLVLHFVPEA--GQAVAEMRRVVRPGGVVA 135
Cdd:COG2230  121 AIVSIGMFEHVGPEnyPAYFAKVARLLKPGGRLL 154
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 39-139 2.66e-15

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 69.77  E-value: 2.66e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  39 KVLDVGCGTGSLTFALADAARlKEIAAIDYSPVFVEEATRRNTN---PRIKIREADACALPF-EDRTFDRAFALLVLHFV 114
Cdd:cd02440    1 RVLDLGCGTGALALALASGPG-ARVTGVDISPVALELARKAAAAllaDNVEVLKGDAEELPPeADESFDVIISDPPLHHL 79

                         90       100
                 ....*....|....*....|....*.
gi 504821067 115 PEAGQAV-AEMRRVVRPGGVVAAAVW 139
Cdd:cd02440   80 VEDLARFlEEARRLLKPGGVLVLTLV 105
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 39-135 3.75e-15

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 72.70  E-value: 3.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   39 KVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEATRRNtNPRIKIREADACALPFEDRTFDRAFALLVLHFVPEAG 118
Cdd:TIGR02072  37 SVLDIGCGTGYLTRALLKRFPQAEFIALDISAGMLAQAKTKL-SENVQFICGDAEKLPLEDSSFDLIVSNLALQWCDDLS 115

                          90
                  ....*....|....*..
gi 504821067  119 QAVAEMRRVVRPGGVVA 135
Cdd:TIGR02072 116 QALSELARVLKPGGLLA 132
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 36-137 1.01e-14

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 69.37  E-value: 1.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   36 DGEKVLDVGCGTGSLTFALADAARLK-EIAAIDYSPVFVEEATRRNTN---PRIKIREADACALP--FEDRTFDRAFALL 109
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEELGPNaEVVGIDISEEAIEKARENAQKlgfDNVEFEQGDIEELPelLEDDKFDVVISNC 82

                          90       100
                  ....*....|....*....|....*...
gi 504821067  110 VLHFVPEAGQAVAEMRRVVRPGGVVAAA 137
Cdd:pfam13847  83 VLNHIPDPDKVLQEILRVLKPGGRLIIS 110
PRK10258 PRK10258
biotin biosynthesis protein BioC; Provisional
 10-135 2.88e-13

biotin biosynthesis protein BioC; Provisional


Pssm-ID: 182340 [Multi-domain]  Cd Length: 251  Bit Score: 67.48  E-value: 2.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  10 AAGYEQlMGRWSRKLAPKFIDFAGVADGEKVLDVGCGTGSLTfaLADAARLKEIAAIDYSPVFVEEATRRNTNPRIKIre 89
Cdd:PRK10258  17 AAHYEQ-HAELQRQSADALLAMLPQRKFTHVLDAGCGPGWMS--RYWRERGSQVTALDLSPPMLAQARQKDAADHYLA-- 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 504821067  90 ADACALPFEDRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVA 135
Cdd:PRK10258  92 GDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVA 137
PLN02490 PLN02490
MPBQ/MSBQ methyltransferase
 18-133 2.58e-09

MPBQ/MSBQ methyltransferase


Pssm-ID: 215270 [Multi-domain]  Cd Length: 340  Bit Score: 56.82  E-value: 2.58e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  18 GRWSRKLAPKFIDFAGVADGE-KVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEATRRNTNPRIKIREADACALP 96
Cdd:PLN02490  94 GHWTEDMRDDALEPADLSDRNlKVVDVGGGTGFTTLGIVKHVDAKNVTILDQSPHQLAKAKQKEPLKECKIIEGDAEDLP 173

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 504821067  97 FEDRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGV 133
Cdd:PLN02490 174 FPTDYADRYVSAGSIEYWPDPQRGIKEAYRVLKIGGK 210
PLN02244 PLN02244
tocopherol O-methyltransferase
 31-192 4.33e-09

tocopherol O-methyltransferase


Pssm-ID: 215135 [Multi-domain]  Cd Length: 340  Bit Score: 56.29  E-value: 4.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  31 FAGVADGE-----KVLDVGCGTGSLTFALAD--AARLKEIAaidYSPVfveEATRRNT-------NPRIKIREADACALP 96
Cdd:PLN02244 108 WAGVPDDDekrpkRIVDVGCGIGGSSRYLARkyGANVKGIT---LSPV---QAARANAlaaaqglSDKVSFQVADALNQP 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  97 FEDRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVAAAVWDHLGGMPGMRMMVDTVAALSEggrRLRARYCFQPMMQ 176
Cdd:PLN02244 182 FEDGQFDLVWSMESGEHMPDKRKFVQELARVAAPGGRIIIVTWCHRDLEPGETSLKPDEQKLLD---KICAAYYLPAWCS 258

                        170
                 ....*....|....*.
gi 504821067 177 PGEMKRTFVEQGLANI 192
Cdd:PLN02244 259 TSDYVKLAESLGLQDI 274
PLN02233 PLN02233
ubiquinone biosynthesis methyltransferase
 29-135 1.09e-08

ubiquinone biosynthesis methyltransferase


Pssm-ID: 177877 [Multi-domain]  Cd Length: 261  Bit Score: 54.51  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  29 IDFAGVADGEKVLDVGCGTGSLTFALADAARLK-EIAAIDYSPVFVEEA-TRRNTNPR-----IKIREADACALPFEDRT 101
Cdd:PLN02233  66 VSWSGAKMGDRVLDLCCGSGDLAFLLSEKVGSDgKVMGLDFSSEQLAVAaSRQELKAKscyknIEWIEGDATDLPFDDCY 145

                         90       100       110
                 ....*....|....*....|....*....|....
gi 504821067 102 FDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVA 135
Cdd:PLN02233 146 FDAITMGYGLRNVVDRLKAMQEMYRVLKPGSRVS 179
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 30-103 1.48e-08

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 54.00  E-value: 1.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  30 DFAGVADGEKVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEAtRRNT--NP---RIKIREADACALP--FEDRTF 102
Cdd:COG4123   31 AFAPVKKGGRVLDLGTGTGVIALMLAQRSPGARITGVEIQPEAAELA-RRNValNGledRITVIHGDLKEFAaeLPPGSF 109


                 .
gi 504821067 103 D 103
Cdd:COG4123  110 D 110
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 18-135 4.97e-08

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 51.49  E-value: 4.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  18 GRWSRKLAPKFIDFAGVADGEKVLDVGCGTGSLtfaLADAARLK-EIAAIDYSPVFVeEATRRNT----NPRIKIREADA 92
Cdd:COG1041    8 GSLDPRLARALVNLAGAKEGDTVLDPFCGTGTI---LIEAGLLGrRVIGSDIDPKMV-EGARENLehygYEDADVIRGDA 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 504821067  93 CALPFEDRTFD---------RAFALLVLHFVPEAGQAVAEMRRVVRPGGVVA 135
Cdd:COG1041   84 RDLPLADESVDaivtdppygRSSKISGEELLELYEKALEEAARVLKPGGRVV 135
rADc smart00650
Ribosomal RNA adenine dimethylases;
27-107 5.30e-08

Ribosomal RNA adenine dimethylases;


Pssm-ID: 128898  Cd Length: 169  Bit Score: 51.36  E-value: 5.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067    27 KFIDFAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEATRR-NTNPRIKIREADACALPFEDRTFDRA 105
Cdd:smart00650   4 KIVRAANLRPGDTVLEIGPGKGALTEELLERA--KRVTAIEIDPRLAPRLREKfAAADNLTVIHGDALKFDLPKLQPYKV 81


                   ..
gi 504821067   106 FA 107
Cdd:smart00650  82 VG 83
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 37-124 1.84e-07

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 50.61  E-value: 1.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  37 GEKVLDVGCGTGSLTFALadAARLKEIAAIDYSPVFVEEATRRNT----NPRIKIREADACALpfeDRTFDRAFALLVL- 111
Cdd:PRK07580  64 GLRILDAGCGVGSLSIPL--ARRGAKVVASDISPQMVEEARERAPeaglAGNITFEVGDLESL---LGRFDTVVCLDVLi 138

                         90
                 ....*....|....
gi 504821067 112 HF-VPEAGQAVAEM 124
Cdd:PRK07580 139 HYpQEDAARMLAHL 152
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
37-135 2.08e-07

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 50.94  E-value: 2.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  37 GEKVLDVGCGTGSLTFAladAARL--KEIAAIDYSPVFVEEAT---RRN-TNPRIKIREADAcalpFEDRTFDRAFA--- 107
Cdd:COG2264  149 GKTVLDVGCGSGILAIA---AAKLgaKRVLAVDIDPVAVEAARenaELNgVEDRIEVVLGDL----LEDGPYDLVVAnil 221

                         90       100       110
                 ....*....|....*....|....*....|.
gi 504821067 108 ---LLVLhfvpeagqaVAEMRRVVRPGGVVA 135
Cdd:COG2264  222 anpLIEL---------APDLAALLKPGGYLI 243
ksgA PRK14896
16S ribosomal RNA methyltransferase A;
27-97 2.21e-07

16S ribosomal RNA methyltransferase A;


Pssm-ID: 237852 [Multi-domain]  Cd Length: 258  Bit Score: 50.67  E-value: 2.21e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504821067  27 KFIDFAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEATRR-NTNPRIKIREADACALPF 97
Cdd:PRK14896  20 RIVEYAEDTDGDPVLEIGPGKGALTDELAKRA--KKVYAIELDPRLAEFLRDDeIAAGNVEIIEGDALKVDL 89
PRK05785 PRK05785
hypothetical protein; Provisional
 19-129 3.37e-07

hypothetical protein; Provisional


Pssm-ID: 235607 [Multi-domain]  Cd Length: 226  Bit Score: 49.69  E-value: 3.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  19 RWSRKLAPKFIDFAGvaDGEKVLDVGCGTGSLTFALaDAARLKEIAAIDYSpvfvEEATRRNTNPRIKIrEADACALPFE 98
Cdd:PRK05785  36 RWRAELVKTILKYCG--RPKKVLDVAAGKGELSYHF-KKVFKYYVVALDYA----ENMLKMNLVADDKV-VGSFEALPFR 107

                         90       100       110
                 ....*....|....*....|....*....|.
gi 504821067  99 DRTFDRAFALLVLHFVPEAGQAVAEMRRVVR 129
Cdd:PRK05785 108 DKSFDVVMSSFALHASDNIEKVIAEFTRVSR 138
RsmA COG0030
16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase ...
 27-108 5.62e-07

16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) [Translation, ribosomal structure and biogenesis]; 16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 439801 [Multi-domain]  Cd Length: 270  Bit Score: 49.35  E-value: 5.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  27 KFIDFAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEATRR-NTNPRIKIREADACALPFEDRTFDRA 105
Cdd:COG0030   28 RIVDAAGITPGDTVLEIGPGLGALTRALLERA--ARVTAVEIDRRLAAILRETfAAYPNLTVIEGDALKVDLPALAAGEP 105


                 ...
gi 504821067 106 FAL 108
Cdd:COG0030  106 LKV 108
CbiT TIGR02469
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes ...
 29-106 2.74e-06

precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes the CbiT methylase which is responsible, in part (along with CbiE), for methylating precorrin-6y (or cobalt-precorrin-6y) at both the 5 and 15 positions as well as the concomitant decarbozylation at C-12. In many organisms, this protein is fused to the CbiE subunit. The fused protein, when found in organisms catalyzing the oxidative version of the cobalamin biosynthesis pathway, is called CobL. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 274148 [Multi-domain]  Cd Length: 124  Bit Score: 45.40  E-value: 2.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   29 IDFAGVADGEKVLDVGCGTGSLTFALADAARLKEIAAIDYSPV---FVEEATRRNTNPRIKIREADAC-ALPFEDRTFDR 104
Cdd:TIGR02469  12 LAKLRLRPGDVLWDIGAGTGSVTIEAARLVPNGRVYAIERNPEaldLIERNLRRFGVSNIVIVEGDAPeAPEALLPDPDA 91


                  ..
gi 504821067  105 AF 106
Cdd:TIGR02469  92 VF 93
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 32-162 6.17e-06

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 46.31  E-value: 6.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  32 AGVADGEKVLDVGCGTGSLTFALADAarLKE---IAAIDYSPVFVEEAtRRNTN-----PRIKIREADAcALPFEDRTFD 103
Cdd:COG2519   87 LDIFPGARVLEAGTGSGALTLALARA--VGPegkVYSYERREDFAEIA-RKNLErfglpDNVELKLGDI-REGIDEGDVD 162

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 504821067 104 RAFAllvlhFVPEAGQAVAEMRRVVRPGGVVAAAVwdhlggmPGMRMMVDTVAALSEGG 162
Cdd:COG2519  163 AVFL-----DMPDPWEALEAVAKALKPGGVLVAYV-------PTVNQVSKLVEALRESG 209
PRK06202 PRK06202
hypothetical protein; Provisional
 40-129 7.64e-06

hypothetical protein; Provisional


Pssm-ID: 180466 [Multi-domain]  Cd Length: 232  Bit Score: 45.76  E-value: 7.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  40 VLDVGCGTGSLTFALADAARLK----EIAAIDYSPVFVEEATRRNTNPRIKIREADACALPFEDRTFDRAFALLVLHFV- 114
Cdd:PRK06202  64 LLDIGCGGGDLAIDLARWARRDglrlEVTAIDPDPRAVAFARANPRRPGVTFRQAVSDELVAEGERFDVVTSNHFLHHLd 143

                         90
                 ....*....|....*.
gi 504821067 115 -PEAGQAVAEMRRVVR 129
Cdd:PRK06202 144 dAEVVRLLADSAALAR 159
PRK14968 PRK14968
putative methyltransferase; Provisional
 29-103 1.49e-05

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 44.50  E-value: 1.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  29 IDFAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEA---TRRN--TNPRIKIREADacaL--PFEDRT 101
Cdd:PRK14968  16 AENAVDKKGDRVLEVGTGSGIVAIVAAKNG--KKVVGVDINPYAVECAkcnAKLNniRNNGVEVIRSD---LfePFRGDK 90


                 ..
gi 504821067 102 FD 103
Cdd:PRK14968  91 FD 92
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
37-135 1.53e-05

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 45.14  E-value: 1.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  37 GEKVLDVGCGTGSLtfALAdAARL--KEIAAIDYSPVFVeEATRRNtnprikiREADACALPFEDRTFDRAFALLV---- 110
Cdd:PRK00517 120 GKTVLDVGCGSGIL--AIA-AAKLgaKKVLAVDIDPQAV-EAAREN-------AELNGVELNVYLPQGDLKADVIVanil 188

                         90       100
                 ....*....|....*....|....*....
gi 504821067 111 ----LHFVPeagqavaEMRRVVRPGGVVA 135
Cdd:PRK00517 189 anplLELAP-------DLARLLKPGGRLI 210
arsM PRK11873
arsenite methyltransferase;
30-235 3.73e-05

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 44.17  E-value: 3.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  30 DFAGVADGEKVLDVGCGTGSLTFAladAARL-----KEIAaIDYSPVFVEEAtRRN------TNprIKIREADACALPFE 98
Cdd:PRK11873  71 ALAELKPGETVLDLGSGGGFDCFL---AARRvgptgKVIG-VDMTPEMLAKA-RANarkagyTN--VEFRLGEIEALPVA 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  99 DRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVaaAVWDhlggmpgmrmMVdTVAALSEGGRRLRARY--CFQPMMQ 176
Cdd:PRK11873 144 DNSVDVIISNCVINLSPDKERVFKEAFRVLKPGGRF--AISD----------VV-LRGELPEEIRNDAELYagCVAGALQ 210

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 504821067 177 PGEMKRTFVEQGLANIT-ESELMIRM-DYGNFDDYWApIGAGEGPLGKYV-ATLDAEERART 235
Cdd:PRK11873 211 EEEYLAMLAEAGFVDITiQPKREYRIpDAREFLEDWG-IAPGRQLDGYIVsATVEATKPAAT 271
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 37-80 4.18e-05

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 43.79  E-value: 4.18e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 504821067   37 GEKVLDVGCGTGSLTFAladAARL--KEIAAIDYSPVFVeEATRRN 80
Cdd:pfam06325 162 GESVLDVGCGSGILAIA---ALKLgaKKVVGVDIDPVAV-RAAKEN 203
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 17-193 5.27e-05

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 42.42  E-value: 5.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   17 MGRWSRKLAPKFIDFAG--VADGEKVLDVGCGTGslTFALADAARLKEIAAIDYSPVFVEEATRRNtnpriKIREADACA 94
Cdd:pfam13489   1 YAHQRERLLADLLLRLLpkLPSPGRVLDFGCGTG--IFLRLLRAQGFSVTGVDPSPIAIERALLNV-----RFDQFDEQE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   95 LPFEDRTFDRAFALLVLHFVPEAGQAVAEMRRVVRPGGVVAAAVWDhlgGMPGMRMMVDTVAALSEGGRRLrarycfqPM 174
Cdd:pfam13489  74 AAVPAGKFDVIVAREVLEHVPDPPALLRQIAALLKPGGLLLLSTPL---ASDEADRLLLEWPYLRPRNGHI-------SL 143

                         170
                  ....*....|....*....
gi 504821067  175 MQPGEMKRTFVEQGLANIT 193
Cdd:pfam13489 144 FSARSLKRLLEEAGFEVVS 162
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
38-137 5.45e-05

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 43.17  E-value: 5.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067    38 EKVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEATRR----NTNPRIKIREADACALPFEDrTFDRAFALLVLHF 113
Cdd:smart00828   1 KRVLDFGCGYGSDLIDLAERHPHLQLHGYTISPEQAEVGRERiralGLQGRIRIFYRDSAKDPFPD-TYDLVFGFEVIHH 79

                           90       100
                   ....*....|....*....|....
gi 504821067   114 VPEAGQAVAEMRRVVRPGGVVAAA 137
Cdd:smart00828  80 IKDKMDLFSNISRHLKDGGHLVLA 103
COG2521 COG2521
Predicted archaeal methyltransferase [General function prediction only];
32-134 9.48e-05

Predicted archaeal methyltransferase [General function prediction only];


Pssm-ID: 442011 [Multi-domain]  Cd Length: 285  Bit Score: 42.97  E-value: 9.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  32 AGVADGEKVLDVGCGTGslTFALADAAR-LKEIAAIDYSPVFVEEAT-----RRNTNPRIKIREADACAL--PFEDRTFD 103
Cdd:COG2521  128 VGVRRGDRVLDTCTGLG--YTAIEALKRgAREVITVEKDPNVLELAElnpwsRELANERIKIILGDASEVikTFPDESFD 205

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 504821067 104 RafallVLHFVPE---AGQAVA-----EMRRVVRPGGVV 134
Cdd:COG2521  206 A-----IIHDPPRfslAGELYSlefyrELYRVLKPGGRL 239
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 22-128 9.71e-05

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 43.24  E-value: 9.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  22 RKLAPKFIDFAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEAT---RRNTNPRIKIREADACALpFE 98
Cdd:COG2265  219 EALYAAALEWLDLTGGERVLDLYCGVGTFALPLARRA--KKVIGVEIVPEAVEDARenaRLNGLKNVEFVAGDLEEV-LP 295

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 504821067  99 DRTFDRAFALLVL-------HfvPEAGQAVAEM--RRVV 128
Cdd:COG2265  296 ELLWGGRPDVVVLdppragaG--PEVLEALAALgpRRIV 332
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 36-138 1.54e-04

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 41.71  E-value: 1.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  36 DGEKVLDVGCGTGSLTfalADAARL----KEIAAIDYSPVFVeEATRRNTNP-----RIKIREADACALPFE-DRTFDRA 105
Cdd:PRK00377  40 KGDMILDIGCGTGSVT---VEASLLvgetGKVYAVDKDEKAI-NLTRRNAEKfgvlnNIVLIKGEAPEILFTiNEKFDRI 115

                         90       100       110
                 ....*....|....*....|....*....|...
gi 504821067 106 FALLVLHFVPEAGQAVAEmrrVVRPGGVVAAAV 138
Cdd:PRK00377 116 FIGGGSEKLKEIISASWE---IIKKGGRIVIDA 145
Trm5 COG2520
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ...
 34-134 1.79e-04

tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442010 [Multi-domain]  Cd Length: 333  Bit Score: 42.16  E-value: 1.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  34 VADGEKVLDVGCGTG--SLTFALADAARlkeIAAIDYSPV---FVEEATRRN-TNPRIKIREADACALPFE-DRTFDRAF 106
Cdd:COG2520  178 VKPGERVLDMFAGVGpfSIPIAKRSGAK---VVAIDINPDaveYLKENIRLNkVEDRVTPILGDAREVAPElEGKADRII 254

                         90       100       110
                 ....*....|....*....|....*....|.
gi 504821067 107 ALLV---LHFVPEAgqavaemRRVVRPGGVV 134
Cdd:COG2520  255 MNLPhsaDEFLDAA-------LRALKPGGVI 278
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 39-103 2.05e-04

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 41.69  E-value: 2.05e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 504821067  39 KVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEATR---RNTNPRIKIREADACAlPFEDRTFD 103
Cdd:PRK09328 111 RVLDLGTGSGAIALALAKERPDAEVTAVDISPEALAVARRnakHGLGARVEFLQGDWFE-PLPGGRFD 177
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 28-135 2.29e-04

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 40.94  E-value: 2.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  28 FIDFAGVADGEKVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVeEATRRN--TN--PRIKIREADaCALPFEDRTFD 103
Cdd:COG2813   41 LLEHLPEPLGGRVLDLGCGYGVIGLALAKRNPEARVTLVDVNARAV-ELARANaaANglENVEVLWSD-GLSGVPDGSFD 118

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 504821067 104 rafalLVL---------HFVPEAGQA-VAEMRRVVRPGG---VVA 135
Cdd:COG2813  119 -----LILsnppfhagrAVDKEVAHAlIADAARHLRPGGelwLVA 158
rrmA PRK11088
23S rRNA methyltransferase A; Provisional
 36-134 2.99e-04

23S rRNA methyltransferase A; Provisional


Pssm-ID: 236841 [Multi-domain]  Cd Length: 272  Bit Score: 41.44  E-value: 2.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  36 DGEKVLDVGCGTGSLTFALADAARLKEIAAI---DYSPVFVEEATRRntNPRIKIREADACALPFEDRTFDraFALLVLh 112
Cdd:PRK11088  85 KATALLDIGCGEGYYTHALADALPEITTMQLfglDISKVAIKYAAKR--YPQVTFCVASSHRLPFADQSLD--AIIRIY- 159

                         90       100
                 ....*....|....*....|..
gi 504821067 113 fvpeAGQAVAEMRRVVRPGGVV 134
Cdd:PRK11088 160 ----APCKAEELARVVKPGGIV 177
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
32-134 3.73e-04

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 40.79  E-value: 3.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  32 AGVADGEKVLDVGCGTGSLTFaLADAARLKEIAAIDYSPVFVEEATR---RNTNP-RIKIREADACALPFEDRtFDRAFA 107
Cdd:COG4076   31 RVVKPGDVVLDIGTGSGLLSM-LAARAGAKKVYAVEVNPDIAAVARRiiaANGLSdRITVINADATDLDLPEK-ADVIIS 108

                         90       100       110
                 ....*....|....*....|....*....|
gi 504821067 108 LLVLHFVPEAGQ-AVAE--MRRVVRPGGVV 134
Cdd:COG4076  109 EMLDTALLDEGQvPILNhaRKRLLKPGGRI 138
Methyltransf_32 pfam13679
Methyltransferase domain; This family appears to be a methyltransferase domain.
 40-80 6.64e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 379330 [Multi-domain]  Cd Length: 138  Bit Score: 39.09  E-value: 6.64e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 504821067   40 VLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEATRRN 80
Cdd:pfam13679  29 IVDHGAGKGYLGFILYYLKYGVRVYGIDTRAELVEKANALA 69
MetW pfam07021
Methionine biosynthesis protein MetW; This family consists of several bacterial and one ...
 30-129 1.12e-03

Methionine biosynthesis protein MetW; This family consists of several bacterial and one archaeal methionine biosynthesis MetW proteins. Biosynthesis of methionine from homoserine in Pseudomonas putida takes place in three steps. The first step is the acylation of homoserine to yield an acyl-L-homoserine. This reaction is catalyzed by the products of the metXW genes and is equivalent to the first step in enterobacteria, gram-positive bacteria and fungi, except that in these microorganizms the reaction is catalyzed by a single polypeptide (the product of the metA gene in Escherichia coli and the met5 gene product in Neurospora crassa). In Pseudomonas putida, as in gram-positive bacteria and certain fungi, the second and third steps are a direct sulfhydrylation that converts the O-acyl-L-homoserine into homocysteine and further methylation to yield methionine. The latter reaction can be mediated by either of the two methionine synthetases present in the cells.


Pssm-ID: 399779  Cd Length: 193  Bit Score: 38.98  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   30 DFAGVA----DGEKVLDVGCGTGSLTFALADAarlKEIAA--IDYSPVFVEEATRRNTNprIKIREADACALPFEDRTFD 103
Cdd:pfam07021   3 DFRYILewipPGSRVLDLGCGDGTLLYLLKEE---KGVDGygIELDAAGVAECVAKGLY--VIQGDLDEGLEHFPDKSFD 77

                          90       100
                  ....*....|....*....|....*.
gi 504821067  104 RAFALLVLHFVPEAGQAVAEMRRVVR 129
Cdd:pfam07021  78 YVILSQTLQATRNPREVLDEMLRIGR 103
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 29-103 1.13e-03

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 39.75  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  29 IDFAGVADGEKVLDVGCGTGSLTFALADAARLKEIAAIDYSPvfveEA---TRRN-----TNPRIKIREADACALPFEDR 100
Cdd:COG2890  105 LALLPAGAPPRVLDLGTGSGAIALALAKERPDARVTAVDISP----DAlavARRNaerlgLEDRVRFLQGDLFEPLPGDG 180


                 ...
gi 504821067 101 TFD 103
Cdd:COG2890  181 RFD 183
PTZ00338 PTZ00338
dimethyladenosine transferase-like protein; Provisional
 27-99 1.20e-03

dimethyladenosine transferase-like protein; Provisional


Pssm-ID: 240367 [Multi-domain]  Cd Length: 294  Bit Score: 39.60  E-value: 1.20e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504821067  27 KFIDFAGVADGEKVLDVGCGTGSLTFALADAArlKEIAAIDYSPVFVEEATRRNTN----PRIKIREADA--CALPFED 99
Cdd:PTZ00338  27 KIVEKAAIKPTDTVLEIGPGTGNLTEKLLQLA--KKVIAIEIDPRMVAELKKRFQNsplaSKLEVIEGDAlkTEFPYFD 103
SpeE COG0421
Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];
38-157 1.34e-03

Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];


Pssm-ID: 440190 [Multi-domain]  Cd Length: 195  Bit Score: 38.66  E-value: 1.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  38 EKVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVE-------EATRRNTNPRIKIREADACA-LPFEDRTFDrafalL 109
Cdd:COG0421   39 KRVLIIGGGDGGLARELLKHPPVERVDVVEIDPEVVElareyfpLLAPAFDDPRLRVVIGDGRAfLREAEESYD-----V 113

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 504821067 110 VLH--FVPEAGQAV-------AEMRRVVRPGGVVAAAVWDHLGGMPGMRMMVDTVAA 157
Cdd:COG0421  114 IIVdlTDPVGPAEGlftrefyEDCRRALKPGGVLVVNLGSPFYGLDLLRRVLATLRE 170
PLN02585 PLN02585
magnesium protoporphyrin IX methyltransferase
 27-79 1.49e-03

magnesium protoporphyrin IX methyltransferase


Pssm-ID: 215319 [Multi-domain]  Cd Length: 315  Bit Score: 39.46  E-value: 1.49e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 504821067  27 KFIDFAGVADGEKVLDVGCGTGSLTFALadAARLKEIAAIDYSPVFVEEATRR 79
Cdd:PLN02585 135 LWLAEDGSLAGVTVCDAGCGTGSLAIPL--ALEGAIVSASDISAAMVAEAERR 185
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 31-157 2.35e-03

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 37.86  E-value: 2.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  31 FAGVADGEKVLDVGCGTGSLTFALADAARLK-EIAAIDYSPVFVEEAtRRNTN-----PRIKIREADAC-ALP-FEDRTF 102
Cdd:COG4122   11 LARLLGAKRILEIGTGTGYSTLWLARALPDDgRLTTIEIDPERAAIA-RENFAraglaDRIRLILGDALeVLPrLADGPF 89

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504821067 103 DraFALL------VLHFVPEAgqavaemRRVVRPGGVVAA--AVWDHLGGMP--------GMRMMVDTVAA 157
Cdd:COG4122   90 D--LVFIdadksnYPDYLELA-------LPLLRPGGLIVAdnVLWHGRVADParrdpstrAIREFNEYLRE 151
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 39-163 3.38e-03

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 37.18  E-value: 3.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067   39 KVLDVGCGTGSLTFALADAARLKEIAAIDYSPVFVEEATR---RNTNPRIKIREADACAlPFEDRTFDrafaLLV----- 110
Cdd:pfam05175  34 KVLDLGCGAGVLGAALAKESPDAELTMVDINARALESAREnlaANGLENGEVVASDVYS-GVEDGKFD----LIIsnppf 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  111 ---LHFVPEAGQA-VAEMRRVVRPGG---VVAAAvwdHLGGMPGMRMMVDTVAALSEGGR 163
Cdd:pfam05175 109 hagLATTYNVAQRfIADAKRHLRPGGelwIVANR---FLGYPPLLEELFGNVEVVAKTNG 165
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
36-100 3.43e-03

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 37.58  E-value: 3.43e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 504821067  36 DGEKVLDVGCGTGSLTF--ALADAARLkeiAAIDYSPVFVEEATR--RNTNPRIKIREADACALPFEDR 100
Cdd:COG2263   45 EGKTVLDLGCGTGMLAIgaALLGAKKV---VGVDIDPEALEIAREnaERLGVRVDFIRADVTRIPLGGS 110
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
27-79 4.30e-03

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 37.35  E-value: 4.30e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 504821067   27 KFIDFAGVADGEKVLDVGCGTGSLTFALADAARLK-EIAAIDYSPVFVEEATRR 79
Cdd:pfam01135  64 MMLELLELKPGMRVLEIGSGSGYLTACFARMVGEVgRVVSIEHIPELVEIARRN 117
Nnt1 COG3897
Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, ...
 37-134 4.76e-03

Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443104 [Multi-domain]  Cd Length: 216  Bit Score: 37.17  E-value: 4.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  37 GEKVLDVGCGTG--SLTFALADAARlkeIAAIDYSPvFVEEATRRNT---NPRIKIREADACALPFEDRT---------F 102
Cdd:COG3897   71 GKRVLELGCGLGlvGIAAAKAGAAD---VTATDYDP-EALAALRLNAalnGVAITTRLGDWRDPPAAGGFdlilggdvlY 146

                         90       100       110
                 ....*....|....*....|....*....|..
gi 504821067 103 DRAFALLVLHFVpeagqavaemRRVVRPGGVV 134
Cdd:COG3897  147 ERDLAEPLLPFL----------DRLAAPGGEV 168
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 32-152 5.09e-03

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 36.99  E-value: 5.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  32 AGVADGEKVLDVGCGTGSLTfALAdAARLKEIAAIDYSPVFVEEATRRNTN---PRIKIREADACALPFEDRTFDRAfal 108
Cdd:COG2518   62 LDLKPGDRVLEIGTGSGYQA-AVL-ARLAGRVYSVERDPELAERARERLAAlgyDNVTVRVGDGALGWPEHAPFDRI--- 136

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 504821067 109 LV---LHFVPEA--GQavaemrrvVRPGGVVAAAVwdhlGGMPGMRMMV 152
Cdd:COG2518  137 IVtaaAPEVPEAllEQ--------LAPGGRLVAPV----GEGGVQRLVL 173
RrnaAD pfam00398
Ribosomal RNA adenine dimethylase;
20-92 6.52e-03

Ribosomal RNA adenine dimethylase;


Pssm-ID: 395321 [Multi-domain]  Cd Length: 263  Bit Score: 37.34  E-value: 6.52e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504821067   20 WSRKLAPKFIDFAGVADGEKVLDVGCGTGSLTFALADaaRLKEIAAIDYSPVFVEEATRR-NTNPRIKIREADA 92
Cdd:pfam00398  14 KDPKVINEIVDKANLRESDTVLEIGPGKGALTVILAK--RAKQVVAIEIDPRLAKLLQKKlSLDENLTVIHQDF 85
Rsm22 COG5459
Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal ...
 24-120 6.97e-03

Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal structure and biogenesis]; Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 444210 [Multi-domain]  Cd Length: 306  Bit Score: 37.24  E-value: 6.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504821067  24 LAPKFIDFAGvadgEKVLDVGCGTGSLTFALADAA-RLKEIAAIDYSP---VFVEEATRRNTNPRIKIREADACAL--PF 97
Cdd:COG5459   72 LAEAGPDFAP----LTVLDVGAGPGTAAWAAADAWpSLLDATLLERSAaalALGRRLARAAANPALETAEWRLADLaaAL 147

                         90       100
                 ....*....|....*....|...
gi 504821067  98 EDRTFDRAFALLVLHFVPEAGQA 120
Cdd:COG5459  148 PAPPADLVVASYVLNELADAARA 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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