|
Name |
Accession |
Description |
Interval |
E-value |
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
1-918 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 1365.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 1 MLKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRR 80
Cdd:COG0653 4 LLKKIFGSRNDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANG-------ETLDDLLPEAFAVVREASKR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 81 VLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLI 160
Cdd:COG0653 77 VLGMRHFDVQLIGGIVLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVGVI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 161 QSGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYL 240
Cdd:COG0653 157 VHGMDPEERRAAYAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 241 KAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNGEVVI 319
Cdd:COG0653 237 RINKLVPRLKRDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENiELVHHLNQALRAHALFKRDVDYIVKDGEVVI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 320 VDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTN 399
Cdd:COG0653 317 VDEFTGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTN 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 400 RPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQ 479
Cdd:COG0653 397 RPMIRKDEPDLVYKTEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAK--QHEREAEIVAQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 480 AGRKGAVTIATNMAGRGTDIILGGNSDYMARLKLREyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkas 559
Cdd:COG0653 475 AGRPGAVTIATNMAGRGTDIVLGGNPEFLAAAELAD-------------------------------------------- 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 560 pqifptelsketeqllkdavnfavkrygerslPELEADEKIAvaaekaptddpvieklrevykAIRKEYEhltsREHDEV 639
Cdd:COG0653 511 --------------------------------RGLEWEEAIA---------------------KIKAEWQ----AEHEEV 533
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 640 VKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESKMLTRSLE 719
Cdd:COG0653 534 LEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRIFGSDRIKGMMDKLGMEEGEPIEHKMVSKAIE 613
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 720 GAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQLDQLVS 799
Cdd:COG0653 614 NAQKKVEGRNFDIRKNLLEYDDVMNDQRKVIYEQRREILEGEDLSETILDMREDVIEDLVDEYIPEGSYPEQWDLEGLEE 693
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 800 KVKEFVYLLQDL-EPQHLEDMSVAEIKTFMHEEVRKAYDIKESQVDqiqPGLMRQAERFFILQQIDTLWREHLQSMDALR 878
Cdd:COG0653 694 ALKELFGLDLPIeEWLDEEGLDEEELRERLLEAADEAYEEKEEELG---PEVMRELERVVLLQVLDRKWREHLDAMDHLR 770
|
890 900 910 920
....*....|....*....|....*....|....*....|
gi 504995345 879 ESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVVYSL 918
Cdd:COG0653 771 QGIGLRGYAQKDPLVEYKREAFELFEEMLDSIKEEVVRYL 810
|
|
| PRK12904 |
PRK12904 |
preprotein translocase subunit SecA; Reviewed |
1-915 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237259 [Multi-domain] Cd Length: 830 Bit Score: 1342.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 1 MLKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKARSdreraevLDELLPEAFAVVREAGRR 80
Cdd:PRK12904 4 LLKKIFGSRNDRELKRLRKIVDKINALEPEMEKLSDEELKAKTAEFKERLAKGET-------LDDLLPEAFAVVREASKR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 81 VLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLI 160
Cdd:PRK12904 77 VLGMRHFDVQLIGGMVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLSVGVI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 161 QSGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYL 240
Cdd:PRK12904 157 LSGMSPEERREAYAADITYGTNNEFGFDYLRDNMVFSLEERVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSSELYK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 241 KAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNGEVVI 319
Cdd:PRK12904 237 RANKIVPTLEKEGDYTVDEKSRTVGLTEEGIEKAEKLLGIENLYDPENiALVHHLNQALRAHELFKRDVDYIVKDGEVVI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 320 VDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTN 399
Cdd:PRK12904 317 VDEFTGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYNLDVVVIPTN 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 400 RPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQ 479
Cdd:PRK12904 397 RPMIRIDHPDLIYKTEKEKFDAVVEDIKERHKKGQPVLVGTVSIEKSELLSKLLKKAGIPHNVLNAK--NHEREAEIIAQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 480 AGRKGAVTIATNMAGRGTDIILGGNSDYMARLKLREYFmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkas 559
Cdd:PRK12904 475 AGRPGAVTIATNMAGRGTDIKLGGNPEMLAAALLEEET------------------------------------------ 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 560 pqifptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklREVYKAIRKEYEhltsREHDEV 639
Cdd:PRK12904 513 ----------------------------------------------------------EEQIAKIKAEWQ----EEHEEV 530
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 640 VKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESKMLTRSLE 719
Cdd:PRK12904 531 LEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRIFGSDRVKGMMDRLGMKEGEAIEHKMVTRAIE 610
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 720 GAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQLDQLVS 799
Cdd:PRK12904 611 NAQKKVEGRNFDIRKQLLEYDDVMNDQRKVIYAQRNEILEGEDLSETILDMREDVIEDLVDAYIPPGSYEEDWDLEGLEE 690
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 800 KVKEFvyLLQDLEPQHL--EDMSVAEIKTFMHEEVRKAYDIKESQVDqiqPGLMRQAERFFILQQIDTLWREHLQSMDAL 877
Cdd:PRK12904 691 ALKTD--FGLELPIEEWleEGLDEEELRERILEAAEEAYEEKEEELG---EEQMREFERVVMLQVLDTKWREHLAAMDHL 765
|
890 900 910
....*....|....*....|....*....|....*...
gi 504995345 878 RESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVV 915
Cdd:PRK12904 766 RQGIGLRGYAQKDPLQEYKREGFELFEEMLDSIKEEVV 803
|
|
| secA |
TIGR00963 |
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are ... |
24-910 |
0e+00 |
|
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are necessary, comprise the standard prokaryotic protein translocation apparatus. Other, specialized translocation systems also exist but are not as broadly distributed. This model describes SecA, an essential member of the apparatus. This model excludes SecA2 of the accessory secretory system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273366 [Multi-domain] Cd Length: 742 Bit Score: 1282.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 24 VNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdrerAEVLDELLPEAFAVVREAGRRVLGMRHFDVQLLGGIVLHKGQIA 103
Cdd:TIGR00963 1 INALEEDYEKLSDEELRNKTNEFKDRLAKQ------GETLDDLLPEAFAVVREASKRVLGMRPFDVQLIGGIALHKGKIA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 104 EMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGMGPAERQRNYACDITYATNS 183
Cdd:TIGR00963 75 EMKTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAEWMGQVYRFLGLSVGLILSGMSPEERREAYACDITYGTNN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 184 ELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLKAAQIARALQKEEHYEVDEKARN 263
Cdd:TIGR00963 155 ELGFDYLRDNMAHSKEEKVQRPFHFAIIDEVDSILIDEARTPLIISGPAEKSTELYVQANKFAKALEKEVDYEVDEKNRA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 264 VLLTDEGFAEAEKLLEVEDLYNPE-DPWAHYIFNAIKAKELFLADVNYIVRNGEVVIVDEFTGRVLSGRRWSDGLHQAIE 342
Cdd:TIGR00963 235 VLLTEQGMKKAEDLLGVDNLYDLEnSPLIHYINNALKAKELFQKDVDYIVRDGEVVIVDEFTGRIMEGRRWSDGLHQAIE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 343 AKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTNRPSGRHDLSDVVYKTEPAKWQAI 422
Cdd:TIGR00963 315 AKEGVEIQNENQTLATITYQNFFRLYEKLSGMTGTAKTEEEEFRKIYNLEVVVVPTNRPVIRKDRPDLVYKTEEEKWKAV 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 423 AEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQAGRKGAVTIATNMAGRGTDIILg 502
Cdd:TIGR00963 395 VEEIKERHAKGQPVLVGTTSVEKSELLSNLLKERGIPHNVLNAK--NHEREAEIIAQAGRKGAVTIATNMAGRGTDIKL- 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 503 gnsdymarlklreyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkaspqifptelsketeqllkdavnfa 582
Cdd:TIGR00963 --------------------------------------------------------------------------------
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 583 vkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsrehDEVVKLGGLHVIGTERHESRRIDNQL 662
Cdd:TIGR00963 472 ------------------------------------------------------EEVKELGGLYVIGTERHESRRIDNQL 497
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 663 RGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESKMLTRSLEGAQKKVETFYYDTRKQVFEYDEV 742
Cdd:TIGR00963 498 RGRSGRQGDPGSSRFFLSLEDNLMRIFGGDRLEGLMRRLGMDDDEPIESKMVSRALESAQKRVEGRNFDIRKQLLEYDDV 577
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 743 MNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQLDQLVSKVKEFVYLLQDLEPQHLEDMSVA 822
Cdd:TIGR00963 578 LNKQREVIYAERRRVLESEDLSELILQMLESTLDRIVDAYINEEKLSEEWDLEGLIEKLKTLFLLDGDLTPEDLENLTSE 657
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 823 EIKTFMHEEVRKAYDIKESQVDQIQpglMRQAERFFILQQIDTLWREHLQSMDALRESVGLRGYGQKDPLIEYKQEGYET 902
Cdd:TIGR00963 658 DLKELLLEKIRAAYDEKEEQLESER---MREFERYVLLQSIDRKWKEHLDAMDLLREGIGLRSYGQKDPLIEYKNEGFNL 734
|
....*...
gi 504995345 903 FLEMMIDI 910
Cdd:TIGR00963 735 FEEMLEDI 742
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
2-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 726.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 2 LKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRRV 81
Cdd:smart00957 1 LKKLFGSKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEG-------ESLDDLLPEAFAVVREAAKRV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 82 LGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQ 161
Cdd:smart00957 74 LGMRHFDVQLIGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 162 SGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERP-TEKYL 240
Cdd:smart00957 154 SGMSPEERRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDEsSDLYH 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 241 KAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPE-DPWAHYIFNAIKAKELFLADVNYIVRNGEVVI 319
Cdd:smart00957 234 RADKFVPRLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPEnIELLHHVNQALRAHYLFKRDVDYIVRDGEVVI 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504995345 320 VDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEF 385
Cdd:smart00957 314 VDEFTGRVMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEF 379
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
2-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 697.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 2 LKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAkarsdreRAEVLDELLPEAFAVVREAGRRV 81
Cdd:pfam07517 1 LKKIFGSPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLR-------EGESLDDILPEAFALVREAAKRV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 82 LGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQ 161
Cdd:pfam07517 74 LGMRHYDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIT 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 162 SGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLK 241
Cdd:pfam07517 154 SDMDPEERRAAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYRE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 242 AAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNGEVVIV 320
Cdd:pfam07517 234 ADRLVKSLEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENvELLHHINQALKAHHLFKRDVDYIVRDGEVVIV 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504995345 321 DEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEF 385
Cdd:pfam07517 314 DEFTGRVMPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
1.34e-137 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 410.00 E-value: 1.34e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 38 QLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRRVLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTL 117
Cdd:cd17928 1 ELRAKTDELRERLAKG-------ETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 118 PAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGMGPAERQRNYACDITYATNSELGFDYLRDNMATV 197
Cdd:cd17928 74 PAYLNALTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSDMSPDERREAYAADITYGTNNELGFDYLRDNMVTS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 198 MSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGqverptekylkaaqiaralqkeehyevdekarnvlltdegfaeaekl 277
Cdd:cd17928 154 KEDLVQRGLNFAIVDEVDSILIDEARTPLIISG----------------------------------------------- 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 278 levedlynpedpwahyifnaikakelfladvnyivrngevvivdeftgrvlsgrrwsdglhqaieakenvdiqnetqTLA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 504995345 358 TITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
1-918 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 1365.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 1 MLKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRR 80
Cdd:COG0653 4 LLKKIFGSRNDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANG-------ETLDDLLPEAFAVVREASKR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 81 VLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLI 160
Cdd:COG0653 77 VLGMRHFDVQLIGGIVLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVGVI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 161 QSGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYL 240
Cdd:COG0653 157 VHGMDPEERRAAYAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 241 KAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNGEVVI 319
Cdd:COG0653 237 RINKLVPRLKRDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENiELVHHLNQALRAHALFKRDVDYIVKDGEVVI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 320 VDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTN 399
Cdd:COG0653 317 VDEFTGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTN 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 400 RPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQ 479
Cdd:COG0653 397 RPMIRKDEPDLVYKTEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAK--QHEREAEIVAQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 480 AGRKGAVTIATNMAGRGTDIILGGNSDYMARLKLREyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkas 559
Cdd:COG0653 475 AGRPGAVTIATNMAGRGTDIVLGGNPEFLAAAELAD-------------------------------------------- 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 560 pqifptelsketeqllkdavnfavkrygerslPELEADEKIAvaaekaptddpvieklrevykAIRKEYEhltsREHDEV 639
Cdd:COG0653 511 --------------------------------RGLEWEEAIA---------------------KIKAEWQ----AEHEEV 533
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 640 VKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESKMLTRSLE 719
Cdd:COG0653 534 LEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRIFGSDRIKGMMDKLGMEEGEPIEHKMVSKAIE 613
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 720 GAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQLDQLVS 799
Cdd:COG0653 614 NAQKKVEGRNFDIRKNLLEYDDVMNDQRKVIYEQRREILEGEDLSETILDMREDVIEDLVDEYIPEGSYPEQWDLEGLEE 693
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 800 KVKEFVYLLQDL-EPQHLEDMSVAEIKTFMHEEVRKAYDIKESQVDqiqPGLMRQAERFFILQQIDTLWREHLQSMDALR 878
Cdd:COG0653 694 ALKELFGLDLPIeEWLDEEGLDEEELRERLLEAADEAYEEKEEELG---PEVMRELERVVLLQVLDRKWREHLDAMDHLR 770
|
890 900 910 920
....*....|....*....|....*....|....*....|
gi 504995345 879 ESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVVYSL 918
Cdd:COG0653 771 QGIGLRGYAQKDPLVEYKREAFELFEEMLDSIKEEVVRYL 810
|
|
| PRK12904 |
PRK12904 |
preprotein translocase subunit SecA; Reviewed |
1-915 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237259 [Multi-domain] Cd Length: 830 Bit Score: 1342.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 1 MLKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKARSdreraevLDELLPEAFAVVREAGRR 80
Cdd:PRK12904 4 LLKKIFGSRNDRELKRLRKIVDKINALEPEMEKLSDEELKAKTAEFKERLAKGET-------LDDLLPEAFAVVREASKR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 81 VLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLI 160
Cdd:PRK12904 77 VLGMRHFDVQLIGGMVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLSVGVI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 161 QSGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYL 240
Cdd:PRK12904 157 LSGMSPEERREAYAADITYGTNNEFGFDYLRDNMVFSLEERVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSSELYK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 241 KAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNGEVVI 319
Cdd:PRK12904 237 RANKIVPTLEKEGDYTVDEKSRTVGLTEEGIEKAEKLLGIENLYDPENiALVHHLNQALRAHELFKRDVDYIVKDGEVVI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 320 VDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTN 399
Cdd:PRK12904 317 VDEFTGRLMPGRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYNLDVVVIPTN 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 400 RPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQ 479
Cdd:PRK12904 397 RPMIRIDHPDLIYKTEKEKFDAVVEDIKERHKKGQPVLVGTVSIEKSELLSKLLKKAGIPHNVLNAK--NHEREAEIIAQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 480 AGRKGAVTIATNMAGRGTDIILGGNSDYMARLKLREYFmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkas 559
Cdd:PRK12904 475 AGRPGAVTIATNMAGRGTDIKLGGNPEMLAAALLEEET------------------------------------------ 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 560 pqifptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklREVYKAIRKEYEhltsREHDEV 639
Cdd:PRK12904 513 ----------------------------------------------------------EEQIAKIKAEWQ----EEHEEV 530
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 640 VKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESKMLTRSLE 719
Cdd:PRK12904 531 LEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRIFGSDRVKGMMDRLGMKEGEAIEHKMVTRAIE 610
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 720 GAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQLDQLVS 799
Cdd:PRK12904 611 NAQKKVEGRNFDIRKQLLEYDDVMNDQRKVIYAQRNEILEGEDLSETILDMREDVIEDLVDAYIPPGSYEEDWDLEGLEE 690
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 800 KVKEFvyLLQDLEPQHL--EDMSVAEIKTFMHEEVRKAYDIKESQVDqiqPGLMRQAERFFILQQIDTLWREHLQSMDAL 877
Cdd:PRK12904 691 ALKTD--FGLELPIEEWleEGLDEEELRERILEAAEEAYEEKEEELG---EEQMREFERVVMLQVLDTKWREHLAAMDHL 765
|
890 900 910
....*....|....*....|....*....|....*...
gi 504995345 878 RESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVV 915
Cdd:PRK12904 766 RQGIGLRGYAQKDPLQEYKREGFELFEEMLDSIKEEVV 803
|
|
| secA |
CHL00122 |
preprotein translocase subunit SecA; Validated |
1-918 |
0e+00 |
|
preprotein translocase subunit SecA; Validated
Pssm-ID: 214371 [Multi-domain] Cd Length: 870 Bit Score: 1314.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 1 MLKTVLGdpNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKARSdreraevLDELLPEAFAVVREAGRR 80
Cdd:CHL00122 1 MFNNLFN--NKSKLNKYQTLVNQINLLEEELKNLTDTELRSKTNKLKKRLSNGQN-------LNKIIPESFALTREASFR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 81 VLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLI 160
Cdd:CHL00122 72 TLGLRHFDVQLIGGLVLNDGKIAEMKTGEGKTLVATLPAYLNALTGKGVHIVTVNDYLAKRDQEWMGQIYRFLGLTVGLI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 161 QSGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYL 240
Cdd:CHL00122 152 QEGMSSEERKKNYLKDITYVTNSELGFDYLRDNMALSLSDVVQRPFNYCIIDEVDSILIDEARTPLIISGQSKTNIDKYI 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 241 KAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPEDPWAHYIFNAIKAKELFLADVNYIVRNGEVVIV 320
Cdd:CHL00122 232 VADELAKYLEKNVHYEVDEKNKNVILTEQGILFIEKILKIEDLYSANDPWIPYILNALKAKELFFKNVHYIVRNNEIIIV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 321 DEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTNR 400
Cdd:CHL00122 312 DEFTGRIMPGRRWSDGLHQAIEAKENLPIRQETETLASITYQNFFLLYPKLSGMTGTAKTEELEFEKIYNLEVVCIPTHR 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 401 PSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARPENVERESEIVAQA 480
Cdd:CHL00122 392 PMLRKDLPDLIYKDELSKWRAIADECLQMHQTGRPILIGTTTIEKSELLSQLLKEYRLPHQLLNAKPENVRRESEIVAQA 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 481 GRKGAVTIATNMAGRGTDIILGGNSDYMARLKLREYFMPKIvmpeqedaltpvsvpgaserarpqgfapgkkvktwkasp 560
Cdd:CHL00122 472 GRKGSITIATNMAGRGTDIILGGNPEFKLKKELYDLLLSYK--------------------------------------- 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 561 qifPTELSKETEQLLKDAVNFAVKRYGERSLPELEADEKIAVAAEKAPTDDPVIEKLREVYKAIRKEYEHLTSREHDEVV 640
Cdd:CHL00122 513 ---SNEKISTISQNFLNILNSLKNDLKFLSLSDFENLKILNEASEISIPKNSYQLSLRFLYNELLEKYKKLQEKEKKIVK 589
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 641 KLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVeEDMPIESKMLTRSLEG 720
Cdd:CHL00122 590 KLGGLYVIGTERHESRRIDNQLRGRAGRQGDPGSSRFFLSLEDNLLRIFGGDKIQNLMQTLNL-DDEPLESKLLSKSLDS 668
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 721 AQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEwqLDQLVSK 800
Cdd:CHL00122 669 AQKKVEEYYYDQRKQLFEYDQVLNKQRKAIYSERRKILESQSLRDWILAYGEQVIDDIITFLKSRKNPNNK--FINLINK 746
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 801 VKEFVYLLQDLEPQHLEDMSVAEIKTFMHEEVRKAYDIKESQVDQIQPGLMRQAERFFILQQIDTLWREHLQSMDALRES 880
Cdd:CHL00122 747 FKELLKLPLCFNKSDLNTLNSGELKKFLYQQFWISYDLKELYLEQIGTGLMRELERSLLLQQIDKSWKEHLQKMSLLREA 826
|
890 900 910
....*....|....*....|....*....|....*...
gi 504995345 881 VGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVVYSL 918
Cdd:CHL00122 827 IGWRSYGQKDPLIEYKNEAFNLFINMINHIRHLVIYDL 864
|
|
| secA |
TIGR00963 |
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are ... |
24-910 |
0e+00 |
|
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are necessary, comprise the standard prokaryotic protein translocation apparatus. Other, specialized translocation systems also exist but are not as broadly distributed. This model describes SecA, an essential member of the apparatus. This model excludes SecA2 of the accessory secretory system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273366 [Multi-domain] Cd Length: 742 Bit Score: 1282.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 24 VNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdrerAEVLDELLPEAFAVVREAGRRVLGMRHFDVQLLGGIVLHKGQIA 103
Cdd:TIGR00963 1 INALEEDYEKLSDEELRNKTNEFKDRLAKQ------GETLDDLLPEAFAVVREASKRVLGMRPFDVQLIGGIALHKGKIA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 104 EMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGMGPAERQRNYACDITYATNS 183
Cdd:TIGR00963 75 EMKTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAEWMGQVYRFLGLSVGLILSGMSPEERREAYACDITYGTNN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 184 ELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLKAAQIARALQKEEHYEVDEKARN 263
Cdd:TIGR00963 155 ELGFDYLRDNMAHSKEEKVQRPFHFAIIDEVDSILIDEARTPLIISGPAEKSTELYVQANKFAKALEKEVDYEVDEKNRA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 264 VLLTDEGFAEAEKLLEVEDLYNPE-DPWAHYIFNAIKAKELFLADVNYIVRNGEVVIVDEFTGRVLSGRRWSDGLHQAIE 342
Cdd:TIGR00963 235 VLLTEQGMKKAEDLLGVDNLYDLEnSPLIHYINNALKAKELFQKDVDYIVRDGEVVIVDEFTGRIMEGRRWSDGLHQAIE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 343 AKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTNRPSGRHDLSDVVYKTEPAKWQAI 422
Cdd:TIGR00963 315 AKEGVEIQNENQTLATITYQNFFRLYEKLSGMTGTAKTEEEEFRKIYNLEVVVVPTNRPVIRKDRPDLVYKTEEEKWKAV 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 423 AEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQAGRKGAVTIATNMAGRGTDIILg 502
Cdd:TIGR00963 395 VEEIKERHAKGQPVLVGTTSVEKSELLSNLLKERGIPHNVLNAK--NHEREAEIIAQAGRKGAVTIATNMAGRGTDIKL- 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 503 gnsdymarlklreyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkaspqifptelsketeqllkdavnfa 582
Cdd:TIGR00963 --------------------------------------------------------------------------------
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 583 vkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsrehDEVVKLGGLHVIGTERHESRRIDNQL 662
Cdd:TIGR00963 472 ------------------------------------------------------EEVKELGGLYVIGTERHESRRIDNQL 497
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 663 RGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESKMLTRSLEGAQKKVETFYYDTRKQVFEYDEV 742
Cdd:TIGR00963 498 RGRSGRQGDPGSSRFFLSLEDNLMRIFGGDRLEGLMRRLGMDDDEPIESKMVSRALESAQKRVEGRNFDIRKQLLEYDDV 577
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 743 MNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQLDQLVSKVKEFVYLLQDLEPQHLEDMSVA 822
Cdd:TIGR00963 578 LNKQREVIYAERRRVLESEDLSELILQMLESTLDRIVDAYINEEKLSEEWDLEGLIEKLKTLFLLDGDLTPEDLENLTSE 657
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 823 EIKTFMHEEVRKAYDIKESQVDQIQpglMRQAERFFILQQIDTLWREHLQSMDALRESVGLRGYGQKDPLIEYKQEGYET 902
Cdd:TIGR00963 658 DLKELLLEKIRAAYDEKEEQLESER---MREFERYVLLQSIDRKWKEHLDAMDLLREGIGLRSYGQKDPLIEYKNEGFNL 734
|
....*...
gi 504995345 903 FLEMMIDI 910
Cdd:TIGR00963 735 FEEMLEDI 742
|
|
| secA |
PRK12906 |
preprotein translocase subunit SecA; Reviewed |
8-914 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237260 [Multi-domain] Cd Length: 796 Bit Score: 1028.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 8 DPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRRVLGMRHF 87
Cdd:PRK12906 10 DNDKRELKRLEKIADKVNALEDEYEKLSDEQLQAKTPEFRDRIKDG-------ESLDDLLPEAFAVAREGAKRVLGLRPF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 88 DVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGMGPA 167
Cdd:PRK12906 83 DVQIIGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALTGKGVHVVTVNEYLSSRDATEMGELYRWLGLTVGLNLNSMSPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 168 ERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLKAAQIAR 247
Cdd:PRK12906 163 EKRAAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKATDLYIRADRFVK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 248 ALQKEE-----------HYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNG 315
Cdd:PRK12906 243 TLIKDEaedgdddedtgDYKIDEKTKTISLTEQGIRKAEKLFGLDNLYDSENtALAHHIDQALRANYIMLKDIDYVVQDG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 316 EVVIVDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTI 395
Cdd:PRK12906 323 EVLIVDEFTGRVMEGRRYSDGLHQAIEAKEGVKIQEENQTLATITYQNFFRMYKKLSGMTGTAKTEEEEFREIYNMEVIT 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 396 IPTNRPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESE 475
Cdd:PRK12906 403 IPTNRPVIRKDSPDLLYPTLDSKFNAVVKEIKERHAKGQPVLVGTVAIESSERLSHLLDEAGIPHAVLNAK--NHAKEAE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 476 IVAQAGRKGAVTIATNMAGRGTDIILGGNsdymarlklreyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvkt 555
Cdd:PRK12906 481 IIMNAGQRGAVTIATNMAGRGTDIKLGPG--------------------------------------------------- 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 556 wkaspqifptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsre 635
Cdd:PRK12906 --------------------------------------------------------------------------------
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 636 hdeVVKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEED-MPIESKML 714
Cdd:PRK12906 510 ---VKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRRFGSDRVKAFLDRLGMNDDdQVIESRMI 586
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 715 TRSLEGAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEG-LDLKEQVIQYAERTMDDIVEAYVNPDlpQEEWQ 793
Cdd:PRK12906 587 TRQVESAQKRVEGNNYDTRKQLLQYDDVMREQREVIYKQRMQVINEdKDLKEVLMPMIKRTVDRQVQMYTQGD--KKDWD 664
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 794 LDQLVSKVKEFVYLLQDLEPQHLEDMSVAEIKTFMHEEVRKAYDIKESQVDqiQPGLMRQAERFFILQQIDTLWREHLQS 873
Cdd:PRK12906 665 LDALRDFIVSAMPDEETFDFEDLKGKSPEELKKRLLDIVEDNYAEKEKQLG--DPTQMLEFEKVVILRVVDSHWTDHIDA 742
|
890 900 910 920
....*....|....*....|....*....|....*....|.
gi 504995345 874 MDALRESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNV 914
Cdd:PRK12906 743 MDQLRQSIGLRGYGQLNPLVEYQEEGYRMFEEMISNIDYDV 783
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
1-915 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 878.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 1 MLKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKARSdreraevLDELLPEAFAVVREAGRR 80
Cdd:PRK09200 1 MKKKLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLASGKT-------LDDILPEAFAVVREAAKR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 81 VLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLI 160
Cdd:PRK09200 74 VLGMRPYDVQLIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLN 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 161 QSGM-GPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKY 239
Cdd:PRK09200 154 FSDIdDASEKKAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 240 LKAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNGEVV 318
Cdd:PRK09200 234 HIAAKFVKTLEEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHqVLYRHIILALRAHVLFKRDVDYIVYDGEIV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 319 IVDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPT 398
Cdd:PRK09200 314 LVDRFTGRVLPGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMFPKLSGMTGTAKTEEKEFFEVYNMEVVQIPT 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 399 NRPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVA 478
Cdd:PRK09200 394 NRPIIRIDYPDKVFVTLDEKYKAVIEEVKERHETGRPVLIGTGSIEQSETFSKLLDEAGIPHNLLNAK--NAAKEAQIIA 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 479 QAGRKGAVTIATNMAGRGTDIILGgnsdymarlklreyfmpkivmpeqedaltpvsvPGASErarpqgfapgkkvktwka 558
Cdd:PRK09200 472 EAGQKGAVTVATNMAGRGTDIKLG---------------------------------EGVHE------------------ 500
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 559 spqifptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsrehde 638
Cdd:PRK09200 --------------------------------------------------------------------------------
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 639 vvkLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDM---PIESKMLT 715
Cdd:PRK09200 501 ---LGGLAVIGTERMESRRVDLQLRGRSGRQGDPGSSQFFISLEDDLLKRFAPEELEKLKKKLKTDAQRltgLLFNRKVH 577
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 716 RSLEGAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEG--LDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQ 793
Cdd:PRK09200 578 KIVVKAQRISEGAGYSAREYALELDDVINIQRDVVYKERNRLLEEddRDLIDIVILMIDVYLEAVAEEYLLEKSLLEEWI 657
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 794 LDQLVSKVKEFVYllqDLEPQHLEdmsvaEIKTFMHEEVRKAYdiKESQVDQIQPGLMRQAERFFILQQIDTLWREHLQS 873
Cdd:PRK09200 658 YENLSFQLNEILS---NTNFPDKK-----EVVQFLLEEAEKQL--KEKRNKLPSATLYNQFLRKVALKAIDQNWVEQVDA 727
|
890 900 910 920
....*....|....*....|....*....|....*....|..
gi 504995345 874 MDALRESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVV 915
Cdd:PRK09200 728 LQQLKEGIGLRQYGQRNPIREYQKEALESFEYMYENIKKDMV 769
|
|
| secA |
PRK12903 |
preprotein translocase subunit SecA; Reviewed |
9-918 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237258 [Multi-domain] Cd Length: 925 Bit Score: 843.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 9 PNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRRVLGMRHFD 88
Cdd:PRK12903 9 FKSTEMRIAEKILKQINDLEPYYRNLTDEELANKTNEFKDRLKNG-------ETLEDIRVEAFAVAREATKRVLGKRPYD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 89 VQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGMGPAE 168
Cdd:PRK12903 82 VQIIGGIILDLGSVAEMKTGEGKTITSIAPVYLNALTGKGVIVSTVNEYLAERDAEEMGKVFNFLGLSVGINKANMDPNL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 169 RQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLKAAQIARA 248
Cdd:PRK12903 162 KREAYACDITYSVHSELGFDYLRDNMVSSKEEKVQRGLNFCLIDEVDSILIDEAKTPLIISGGQSNDSNLYLAADQFVRT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 249 LqKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPEDP-WAHYIFNAIKAKELFLADVNYIVRNGEVVIVDEFTGRV 327
Cdd:PRK12903 242 L-KEDDYKIDEETKAISLTEKGIKKANKFFKLKNLYDIENSeLVHRIQNALRAHKVMKEDVEYIVRDGKIELVDQFTGRI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 328 LSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTNRPSGRHDL 407
Cdd:PRK12903 321 MEGRSYSEGLQQAIQAKEMVEIEPETKTLATITYQNFFRLFKKLSGMTGTAKTEEQEFIDIYNMRVNVVPTNKPVIRKDE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 408 SDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQAGRKGAVT 487
Cdd:PRK12903 401 PDSIFGTKHAKWKAVVKEVKRVHKKGQPILIGTAQVEDSETLHELLLEANIPHTVLNAK--QNAREAEIIAKAGQKGAIT 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 488 IATNMAGRGTDIILGgnsdymarlklreyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkaspqifptel 567
Cdd:PRK12903 479 IATNMAGRGTDIKLS----------------------------------------------------------------- 493
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 568 sketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsrehDEVVKLGGLHV 647
Cdd:PRK12903 494 ---------------------------------------------------------------------KEVLELGGLYV 504
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 648 IGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIF-GGDRvagLMNAFRVEEDMPIESKMLTRSLEGAQKKVE 726
Cdd:PRK12903 505 LGTDKAESRRIDNQLRGRSGRQGDVGESRFFISLDDQLFRRFsNFDK---IKEAFKKLGDDEIKSKFFSKALLNAQKKIE 581
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 727 TFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPdLPQEEWQLDQLVSKV-KEFV 805
Cdd:PRK12903 582 GFNFDTRKNVLDYDDVIRQQRDLIYAQRDLILIADDLSHVIEKMISRAVEQILKNSFII-LKNNTINYKELVEFLnDNLL 660
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 806 YLLQ-DLEPQHLEDMSVAEIKTFMHEEVRKAYDIK-ESQVDQIQPGLMRQAERFFILQQIDTLWREHLQSMDALRESVGL 883
Cdd:PRK12903 661 RITHfKFSEKDFENYHKEELAQYLIEALNEIYFKKrQVILDKIALNTFFESERYIILSALDKYWQNHIDTMDKLRSGVNL 740
|
890 900 910
....*....|....*....|....*....|....*
gi 504995345 884 RGYGQKDPLIEYKQEGYETFLEMMIDIRRNVVYSL 918
Cdd:PRK12903 741 VQYSQKNPYQVYTEEGTKKFNILLQEIAYDVIVSL 775
|
|
| SecA2_Bac_anthr |
TIGR04397 |
accessory Sec system translocase SecA2, Bacillus type; Members of this family always occur in ... |
2-914 |
0e+00 |
|
accessory Sec system translocase SecA2, Bacillus type; Members of this family always occur in genomes with the preprotein translocase SecA (TIGR00963) and closely resemble it, hence the designation SecA2. However, this appears to mark a different type of accessory Sec system SecA2 (TIGR03714) from the serine-rich glycoprotein type found in Staphylococcus and Streptococcus, and the actinobacterial SecA2 (TIGR04221). This type occurs in species including Bacillus anthracis, Geobacillus thermoglucosidasius, Solibacillus silvestris, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 275190 [Multi-domain] Cd Length: 774 Bit Score: 842.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 2 LKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLakarsdrERAEVLDELLPEAFAVVREAGRRV 81
Cdd:TIGR04397 1 VKKLKGDSSARELKRYEKLVAQINELEPKMEKLSDEELRQKTITFKERL-------EDGKTVDDIKVEAFAVVREASKRV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 82 LGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQ 161
Cdd:TIGR04397 74 LGMRHYDVQLIGGLVLLEGNIAEMPTGEGKTLVASLPSYLRALEGKGVHVITVNDYLARRDRELIGQIHEFLGLTVGLNV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 162 SGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLK 241
Cdd:TIGR04397 154 PMMEASEKKEAYQADITYGVGTEFGFDYLRDNMVYSLSDKVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKTGSSSELHYI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 242 AAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPE-DPWAHYIFNAIKAKELFLADVNYIVRNGEVVIV 320
Cdd:TIGR04397 234 CARIIKSFEETEDYEYDPETKAASLTEEGITKIERAFGIDNLYDLEhQTLYHYLIQALRAHVLFKRDVDYIVKDGKIELV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 321 DEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTNR 400
Cdd:TIGR04397 314 DMFTGRIMEGRSLSDGLHQAIEAKEGLEITEENKTQASITIQNYFRMYPKLSGMTGTAKTEEKEFRETYGMDVVQIPTNR 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 401 PSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQA 480
Cdd:TIGR04397 394 PRIRVDWPDRVFMTYEAKYKAVAKEVKKRHETGQPILIGTTSILQSETVAKYLDKEKIPYQLLNAK--TVEQEADLIALA 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 481 GRKGAVTIATNMAGRGTDIILGgnsdymarlklreyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkasp 560
Cdd:TIGR04397 472 GQKGQVTIATNMAGRGTDILLG---------------------------------------------------------- 493
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 561 qifptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsrehDEVV 640
Cdd:TIGR04397 494 ----------------------------------------------------------------------------EGVH 497
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 641 KLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEEDMPIESKMLTRSLEG 720
Cdd:TIGR04397 498 ELGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSQFIISLEDDMFRRYAAEELEKWKKKLKTDETGEILNKDVHEFVDK 577
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 721 AQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDLPQEEWQLDQLVSK 800
Cdd:TIGR04397 578 VQRIIEGSHYSAREYNLKLDDVINEQRNVIYQLRDKLLEEEDAISEVLKMIRSAVEQIIDQYCPEEVLPEEWDLERLTEE 657
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 801 VKEFVY---LLQDLEPQHLEdmsvaEIKTFMHEEVRKAYDIKESQVDQIQpglMRQAERFFILQQIDTLWREHLQSMDAL 877
Cdd:TIGR04397 658 LNRIFPvtfVTFDKRIADKE-----ELKDLVKDTYEQYIAALEKLPENEE---IQMRLKHVMLSVIDAHWTRHLDAMNLL 729
|
890 900 910
....*....|....*....|....*....|....*..
gi 504995345 878 RESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNV 914
Cdd:TIGR04397 730 KEGIGLRSYQQEDPMRLYQKEGLELFEAMYQNIEREI 766
|
|
| secA |
PRK12901 |
preprotein translocase subunit SecA; Reviewed |
2-915 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237256 [Multi-domain] Cd Length: 1112 Bit Score: 777.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 2 LKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKARSD--------RERAE------------ 61
Cdd:PRK12901 5 LKKLFGDKSERDLKEIQPIVEKIKAEYPELEALSNDELRAKTDEFKQYIKEAVADidakieelKAEAIesldiderediy 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 62 ----------------VLDELLPEAFAVVREAGRRVLG------------------------------------------ 83
Cdd:PRK12901 85 aqidklekeayeilekVLDEILPEAFAIVKETARRFAEneeievtatdfdrelaatkdfvtiegdkaiwknhwdaggnei 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 84 ---MRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLI 160
Cdd:PRK12901 165 twdMVHYDVQLIGGVVLHQGKIAEMATGEGKTLVATLPVYLNALTGNGVHVVTVNDYLAKRDSEWMGPLYEFHGLSVDCI 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 161 QSGM-GPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVE------ 233
Cdd:PRK12901 245 DKHQpNSEARRKAYNADITYGTNNEFGFDYLRDNMAHSPEDLVQRKHNYAIVDEVDSVLIDDARTPLIISGPVPkgddqe 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 234 ----------------------------------------------------RPTEKYLKAAQIARALQK-EEHY----- 255
Cdd:PRK12901 325 feelkprverlveaqrklatqflaeakkliaegdkkegglallrayrglpknKALIKFLSEEGIKALLQKtENFYmqdnn 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 256 ------------EVDEKARNVLLTDEGFAE----------------AEKLLEVEDLYN-PEDPWA--------------- 291
Cdd:PRK12901 405 rempevdeelyfVIDEKNNSVELTDKGIDYitgndedpdffvlpdiGTELAEIENEGGlDEEEEAekkeelfqdysvkse 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 292 --HYIFNAIKAKELFLADVNYIVRNGEVVIVDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYP 369
Cdd:PRK12901 485 rvHTLNQLLKAYTLFEKDDEYVVMDGKVKIVDEQTGRIMEGRRYSDGLHQAIEAKENVKIEAATQTFATITLQNYFRMYH 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 370 KLAGMTGTAKTEESEFEKIYNLQVTIIPTNRPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELL 449
Cdd:PRK12901 565 KLAGMTGTAETEAGEFWDIYKLDVVVIPTNRPIARKDKEDLVYKTKREKYNAVIEEITELSEAGRPVLVGTTSVEISELL 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 450 SGLLKQRAVPHELLNARPEnvERESEIVAQAGRKGAVTIATNMAGRGTDIILGgnsdymarlklreyfmpkivmpeqeda 529
Cdd:PRK12901 645 SRMLKMRKIPHNVLNAKLH--QKEAEIVAEAGQPGTVTIATNMAGRGTDIKLS--------------------------- 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 530 ltpvsvpgaserarpqgfapgkkvktwkaspqifptelsketeqllkdavnfavkrygerslpeleadekiavaaekapt 609
Cdd:PRK12901 --------------------------------------------------------------------------------
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 610 ddpvieklrevykairkeyehltsrehDEVVKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIF 689
Cdd:PRK12901 696 ---------------------------PEVKAAGGLAIIGTERHESRRVDRQLRGRAGRQGDPGSSQFYVSLEDNLMRLF 748
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 690 GGDRVAGLMNAFRVEEDMPIESKMLTRSLEGAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQ 769
Cdd:PRK12901 749 GSERIAKVMDRMGLKEGEVIQHSMISKSIERAQKKVEENNFGIRKRLLEYDDVMNSQREVIYKRRRHALMGERLGMDIAN 828
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 770 YAERTMDDIVEAY------------------VNPDLPQEEW---QLDQLVSKVKEFVY------LLQDLEPQHLEDMSVA 822
Cdd:PRK12901 829 MIYDVCEAIVENNkvandykgfkfelirtlaMESPITEEEFnklKKDELTDKLYDAALenyqrkMERIAEIAFPVIKQVY 908
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 823 EIKTFMHEEV-------RKAYDIK-------ESQVDQIqpglMRQAERFFILQQIDTLWREHLQSMDALRESVGLRGYGQ 888
Cdd:PRK12901 909 EEQGNMYERIvvpftdgKRTLNVVtnlkeayETEGKEI----VKDFEKNITLHIIDEAWKEHLREMDELKQSVQNASYEQ 984
|
1130 1140
....*....|....*....|....*..
gi 504995345 889 KDPLIEYKQEGYETFLEMMIDIRRNVV 915
Cdd:PRK12901 985 KDPLLIYKFESFELFKNMVDKVNREVI 1011
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
2-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 726.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 2 LKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRRV 81
Cdd:smart00957 1 LKKLFGSKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEG-------ESLDDLLPEAFAVVREAAKRV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 82 LGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQ 161
Cdd:smart00957 74 LGMRHFDVQLIGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 162 SGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERP-TEKYL 240
Cdd:smart00957 154 SGMSPEERRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDEsSDLYH 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 241 KAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPE-DPWAHYIFNAIKAKELFLADVNYIVRNGEVVI 319
Cdd:smart00957 234 RADKFVPRLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPEnIELLHHVNQALRAHYLFKRDVDYIVRDGEVVI 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504995345 320 VDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEF 385
Cdd:smart00957 314 VDEFTGRVMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEF 379
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
2-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 697.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 2 LKTVLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAkarsdreRAEVLDELLPEAFAVVREAGRRV 81
Cdd:pfam07517 1 LKKIFGSPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLR-------EGESLDDILPEAFALVREAAKRV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 82 LGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQ 161
Cdd:pfam07517 74 LGMRHYDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIT 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 162 SGMGPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLK 241
Cdd:pfam07517 154 SDMDPEERRAAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYRE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 242 AAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVRNGEVVIV 320
Cdd:pfam07517 234 ADRLVKSLEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENvELLHHINQALKAHHLFKRDVDYIVRDGEVVIV 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 504995345 321 DEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEF 385
Cdd:pfam07517 314 DEFTGRVMPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
10-911 |
0e+00 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 695.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 10 NARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLAKARSdreraevLDELLPEAFAVVREAGRRVLGMRHFDV 89
Cdd:TIGR03714 2 NNLRLKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVEGES-------LDDILPEAYAVVREADKRVLGMFPYDV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 90 QLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGL-----IQSGM 164
Cdd:TIGR03714 75 QVLGAIVLHQGNIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLgvvddPDEEY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 165 GPAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKYLKAAQ 244
Cdd:TIGR03714 155 DANEKRKIYNSDIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 245 IARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPE--DPWAHYIFnAIKAKELFLADVNYIVRNGEVVIVDE 322
Cdd:TIGR03714 235 FVRTLKEDVDYIFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEyfELVRHINL-ALRAHYLFKRNKDYVVTNGEVVLLDR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 323 FTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTNRPS 402
Cdd:TIGR03714 314 ITGRLLEGTKLQSGIHQAIEAKEHVELSKETRAMASITYQNLFKMFNKLSGMTGTGKVAEKEFIETYSLSVVKIPTNKPI 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 403 GRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNArpENVERESEIVAQAGR 482
Cdd:TIGR03714 394 IRIDYPDKIYATLPEKLMATLEDVKEYHETGQPVLLITGSVEMSEIYSELLLREGIPHNLLNA--QNAAKEAQIIAEAGQ 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 483 KGAVTIATNMAGRGTDIILGgnsdymarlklreyfmpkivmpeqedaltpvsvPGASErarpqgfapgkkvktwkaspqi 562
Cdd:TIGR03714 472 KGAVTVATSMAGRGTDIKLG---------------------------------KGVAE---------------------- 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 563 fptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsrehdevvkL 642
Cdd:TIGR03714 497 -------------------------------------------------------------------------------L 497
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 643 GGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGLMNAFRVEE----DMPIESKMLTRSL 718
Cdd:TIGR03714 498 GGLAVIGTERMENSRVDLQLRGRSGRQGDPGSSQFFVSLEDDLIKRWSPSWLKKYYKKYSVKDsklkPSALFKRRFRKIV 577
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 719 EGAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQyaeRTMDDIVEAYVNpdlpqeewqlDQLV 798
Cdd:TIGR03714 578 EKAQRASEDKGESAREQTNEFEESLSIQRENIYAERNRLIEGSDFLDDDVD---QIIDDVFNMYAE----------EQDL 644
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 799 SKVKEFV-YLLQDLEPQHLED------MSVAEIKTFMHEEVRKAYDIKESQVdqIQPGLMRQAERFFILQQIDTLWREHL 871
Cdd:TIGR03714 645 SNKSLLKrFILENLSYQFKNDpdefdlKNKEAIKDFLKEIADKELSEKKKVL--NNDYLFNDFERLSILKAIDENWIEQV 722
|
890 900 910 920
....*....|....*....|....*....|....*....|
gi 504995345 872 QSMDALRESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIR 911
Cdd:TIGR03714 723 DYLQQLKTVVTNRQNGQRNPIFEYHKEALESYEYMKKEIK 762
|
|
| secA |
PRK12898 |
preprotein translocase subunit SecA; Reviewed |
5-745 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237253 [Multi-domain] Cd Length: 656 Bit Score: 649.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 5 VLGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKGKTAEFQQKLakarsdRERAEVLDELLPEAFAVVREAGRRVLGM 84
Cdd:PRK12898 29 LAGRVRGRAARRQRLLADRVLAAAEALAGLSEEALRARSLALRARL------RARDGFRDALLAEAFALVREASGRVLGQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 85 RHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGM 164
Cdd:PRK12898 103 RHFDVQLMGGLALLSGRLAEMQTGEGKTLTATLPAGTAALAGLPVHVITVNDYLAERDAELMRPLYEALGLTVGCVVEDQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 165 GPAERQRNYACDITYATNSELGFDYLRDN--MATVMSD-----------------VVQRPFNYCVIDEVDSVLIDEARTP 225
Cdd:PRK12898 183 SPDERRAAYGADITYCTNKELVFDYLRDRlaLGQRASDarlaleslhgrssrstqLLLRGLHFAIVDEADSVLIDEARTP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 226 LIISGQVERP--TEKYLKAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLynpedPWA------HYIFNA 297
Cdd:PRK12898 263 LIISAPAKEAdeAEVYRQALELAAQLKEGEDYTIDAAEKRIELTEAGRARIAELAESLPP-----AWRgavrreELVRQA 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 298 IKAKELFLADVNYIVRNGEVVIVDEFTGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGT 377
Cdd:PRK12898 338 LSALHLFRRDEHYIVRDGKVVIVDEFTGRVMPDRSWEDGLHQMIEAKEGCELTDPRETLARITYQRFFRRYLRLAGMTGT 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 378 AKTEESEFEKIYNLQVTIIPTNRPSGRHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRA 457
Cdd:PRK12898 418 AREVAGELWSVYGLPVVRIPTNRPSQRRHLPDEVFLTAAAKWAAVAARVRELHAQGRPVLVGTRSVAASERLSALLREAG 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 458 VPHELLNARpeNVERESEIVAQAGRKGAVTIATNMAGRGTDIILGgnsdymarlklreyfmpkivmpeqedaltpvsvpg 537
Cdd:PRK12898 498 LPHQVLNAK--QDAEEAAIVARAGQRGRITVATNMAGRGTDIKLE----------------------------------- 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 538 aserarpqgfapgkkvktwkaspqifptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpviekl 617
Cdd:PRK12898 --------------------------------------------------------------------------------
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 618 revykairkeyehltsrehDEVVKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFGGDRVAGL 697
Cdd:PRK12898 541 -------------------PGVAARGGLHVILTERHDSARIDRQLAGRCGRQGDPGSYEAILSLEDDLLQSFLGSRGLAI 601
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|
gi 504995345 698 --MNAFRVEEDMPIESKMLTRslegAQKKVETFYYDTRKQVFEYDEVMNN 745
Cdd:PRK12898 602 rrMELLGPRGGRALGALLLRR----AQRRAERLHARARRALLHADEQLDK 647
|
|
| SecA2_Mycobac |
TIGR04221 |
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the ... |
6-915 |
4.40e-171 |
|
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the SecA2 subunit of the Mycobacterial type of accessory secretory system. This family is quite different SecA2 of the Staph/Strep type (TIGR03714).
Pssm-ID: 275062 [Multi-domain] Cd Length: 762 Bit Score: 516.69 E-value: 4.40e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 6 LGDPNARKLKKYQPYVVDVNVLEDEIQALSDDQLKgktaefqqklAKARSDRERAEVLDelLPEAFAVVREAGRRVLGMR 85
Cdd:TIGR04221 9 LGSSTERNQKRSLAIVPAAASRMKELSALDDEELT----------KAARDLVLSGEAAD--AAQFLAILREAAERTLGMR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 86 HFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGMG 165
Cdd:TIGR04221 77 PFDVQLLGALRLLAGDVIEMATGEGKTLAGAMAATGFALLGKRVHVVTVNDYLARRDAEWMGPLVDFFGLTVGWVTEDST 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 166 PAERQRNYACDITYATNSELGFDYLRDNMATVMSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGQVERPTEKyLKAAQI 245
Cdd:TIGR04221 157 PDERRAAYACDVTYASVNEIGFDVLRDQLVTDRADLVQPAADVALIDEADSVLVDEALVPLVLAGNEPGEAPR-GRITDL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 246 ARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPEDPWAHY--IFNAIKAKELFLADVNYIVRNGEVVIVDEF 323
Cdd:TIGR04221 236 VRRLREDKHYTVDEDGRNVHLTEDGARAVEAELGIDDLYSEEHVGTTLvqVNVALHAHALLIRDVHYIVRDGKVALIDAS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 324 TGRVLSGRRWSDGLHQAIEAKENVDIQNETQTLATITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPTNRPSG 403
Cdd:TIGR04221 316 RGRVAQLQRWPDGLQAAVEAKEGLEVTEGGEVLDTITVQALIGRYPTVCGMTGTAVAAGEQLRQFYDLGVSVIPPNTPNI 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 404 RHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQAGRK 483
Cdd:TIGR04221 396 RFDEADRVYATAAEKNDAIVEEIAEVHKTGQPVLVGTQDVAESEELAEALLEAGVPCNVLNAK--NDAEEAAIIAEAGDI 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 484 GAVTIATNMAGRGTDIILGGnsdymarlklreyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkaspqif 563
Cdd:TIGR04221 474 GAVTVSTQMAGRGTDIRLGG------------------------------------------------------------ 493
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 564 ptelsketeqllkdavnfavkrygerslpeleADEKiavaaekaptddpvieklrevykairkeyehltsrEHDEVVKLG 643
Cdd:TIGR04221 494 --------------------------------SDEA-----------------------------------DHDRVAELG 506
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 644 GLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLSLEDNLLRIFG-GDRVAGlmnafRVEEDMPIESKMLTRSLEGAQ 722
Cdd:TIGR04221 507 GLHVIGTGRHRTARLDNQLRGRAGRQGDPGSSVFFVSLEDDVVAVGGaGETVPA-----QPAEDGRIESPRVQDFVDHAQ 581
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 723 KKVETFYYDTRKQVFEYDEVMNNQrRAIYAERRRVLegLDLKEQVIQYAERTMDdiveayvnpdlpqeewqldqlvskvk 802
Cdd:TIGR04221 582 RVAEGQLLEIHANTWRYNQLIAQQ-RDIIDERRETL--LDTDTAWQELSERAAD-------------------------- 632
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 803 efvyllqdlepqhledmSVAEIKTFMHEEVRKaydikesqvdqiqpglmrQAERFFILQQIDTLWREHLQSMDALRESVG 882
Cdd:TIGR04221 633 -----------------RAAELKKEVSEDALE------------------RAAREIMLYHLDRGWAEHLAYLDDVRESIH 677
|
890 900 910
....*....|....*....|....*....|...
gi 504995345 883 LRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVV 915
Cdd:TIGR04221 678 LRALGRETPLDEFHRMAVRAFKELAQRAVDKAV 710
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
1.34e-137 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 410.00 E-value: 1.34e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 38 QLKGKTAEFQQKLAKArsdreraEVLDELLPEAFAVVREAGRRVLGMRHFDVQLLGGIVLHKGQIAEMKTGEGKTLVSTL 117
Cdd:cd17928 1 ELRAKTDELRERLAKG-------ETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 118 PAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGLSVGLIQSGMGPAERQRNYACDITYATNSELGFDYLRDNMATV 197
Cdd:cd17928 74 PAYLNALTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSDMSPDERREAYAADITYGTNNELGFDYLRDNMVTS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 198 MSDVVQRPFNYCVIDEVDSVLIDEARTPLIISGqverptekylkaaqiaralqkeehyevdekarnvlltdegfaeaekl 277
Cdd:cd17928 154 KEDLVQRGLNFAIVDEVDSILIDEARTPLIISG----------------------------------------------- 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 278 levedlynpedpwahyifnaikakelfladvnyivrngevvivdeftgrvlsgrrwsdglhqaieakenvdiqnetqTLA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 504995345 358 TITYQNFFLLYPKLAGMTGTAKTEESEFEKIYNLQVTIIPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| SecA_SW |
pfam07516 |
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts ... |
708-918 |
2.37e-88 |
|
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This family is composed of two C-terminal alpha helical subdomains: the wing and scaffold subdomains.
Pssm-ID: 462189 [Multi-domain] Cd Length: 213 Bit Score: 280.53 E-value: 2.37e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 708 PIESKMLTRSLEGAQKKVETFYYDTRKQVFEYDEVMNNQRRAIYAERRRVLEGLDLKEQVIQYAERTMDDIVEAYVNPDL 787
Cdd:pfam07516 1 PIEHKMVSKAIENAQKKVEGRNFDIRKNLLEYDDVMNQQREVIYAQRREILEGEDLKEDILEMIEDVVDDIVDEYIPPEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 788 PQEEWQLDQLVSKVKE-FVYLLQDLEPQHLEDMSVAEIKTFMHEEVRKAYDIKEsqvDQIQPGLMRQAERFFILQQIDTL 866
Cdd:pfam07516 81 SPEEWDLEGLKEALNEiFGLELPISEWEEEEDLDKEELKERLLEAAEEAYEEKE---EEIGPELMRELERVVLLQVIDSK 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 504995345 867 WREHLQSMDALRESVGLRGYGQKDPLIEYKQEGYETFLEMMIDIRRNVVYSL 918
Cdd:pfam07516 158 WKEHLDAMDQLRQGIGLRAYGQKDPLVEYKREGFELFEEMLDAIREEVVRYL 209
|
|
| SF2_C_secA |
cd18803 |
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the ... |
404-680 |
2.64e-67 |
|
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350190 [Multi-domain] Cd Length: 141 Bit Score: 220.88 E-value: 2.64e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 404 RHDLSDVVYKTEPAKWQAIAEECAQMHEEGRPVLVGTTSVEKSELLSGLLKQRAVPHELLNARpeNVERESEIVAQAGRK 483
Cdd:cd18803 1 RKDLPDLVYKTEEEKWKAIVEEVKELHAKGQPVLVGTRSVEKSELLSALLKEEGIPHNVLNAK--NHAREAEIIAEAGQK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 484 GAVTIATNMAGRGTDIILGGNsdymarlklreyfmpkivmpeqedaltpvsvpgaserarpqgfapgkkvktwkaspqif 563
Cdd:cd18803 79 GAVTIATNMAGRGTDIKLGGN----------------------------------------------------------- 99
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 564 ptelsketeqllkdavnfavkrygerslpeleadekiavaaekaptddpvieklrevykairkeyehltsrehdeVVKLG 643
Cdd:cd18803 100 ---------------------------------------------------------------------------VEELG 104
|
250 260 270
....*....|....*....|....*....|....*..
gi 504995345 644 GLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFLS 680
Cdd:cd18803 105 GLHVIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLS 141
|
|
| SecA_PP_bind |
pfam01043 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
235-342 |
6.59e-54 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 460039 [Multi-domain] Cd Length: 110 Bit Score: 182.61 E-value: 6.59e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 235 PTEKYLKAAQIARALQKEEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPED-PWAHYIFNAIKAKELFLADVNYIVR 313
Cdd:pfam01043 2 STELYRQADKFVKQLKEDEDYEVDEKAKTVELTEEGIEKAEKLLGIDNLYDPENiELVHHINQALKAHHLFKRDVDYIVK 81
|
90 100
....*....|....*....|....*....
gi 504995345 314 NGEVVIVDEFTGRVLSGRRWSDGLHQAIE 342
Cdd:pfam01043 82 DGEVVIVDEFTGRLMPGRRYSDGLHQAIE 110
|
|
| SecA_PP_bind |
smart00958 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
231-342 |
6.98e-53 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 214938 [Multi-domain] Cd Length: 114 Bit Score: 179.96 E-value: 6.98e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 231 QVERPTEKYLKAAQIARALQK-EEHYEVDEKARNVLLTDEGFAEAEKLLEVEDLYNPE-DPWAHYIFNAIKAKELFLADV 308
Cdd:smart00958 1 PAEDSSELYKRADELVPTLKKdEEDYEVDEKSRQVALTEEGIEKAEKLLGIDNLYDPEnIELVHHVNQALRAHKLFKRDV 80
|
90 100 110
....*....|....*....|....*....|....
gi 504995345 309 NYIVRNGEVVIVDEFTGRVLSGRRWSDGLHQAIE 342
Cdd:smart00958 81 DYIVRDGEVVIVDEFTGRVMPGRRWSDGLHQAIE 114
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
98-227 |
6.78e-19 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 83.99 E-value: 6.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 98 HKGQIAEMKTGEGKTLVSTLPAYLNALS-GKGVHVVTVNDYLARRDAEWMGQVHRyLGLSVGLIQSGMGPAERQRNYA-- 174
Cdd:cd00046 1 GENVLITAPTGSGKTLAALLAALLLLLKkGKKVLVLVPTKALALQTAERLRELFG-PGIRVAVLVGGSSAEEREKNKLgd 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 504995345 175 CDITYATNSELGFDYLRdnmatvMSDVVQRPFNYCVIDEVDSVLIDEARTPLI 227
Cdd:cd00046 80 ADIIIATPDMLLNLLLR------EDRLFLKDLKLIIVDEAHALLIDSRGALIL 126
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
100-175 |
1.03e-09 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 55.99 E-value: 1.03e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 504995345 100 GQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVVTVNDYLARRDAEWMGQVHRYLGlsvglIQSGMGPAERQRNYAC 175
Cdd:cd17912 1 NILHLGPTGSGKTLVAIQKIASAMSSGKSVLVVTPTKLLAHEILIVIDEIQ*ILD-----PAAGWAWATRALLGLK 71
|
|
| DEAD-like_helicase_C |
cd09300 |
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases ... |
642-678 |
5.91e-07 |
|
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases is composed of two superfamilies, SF1 and SF2, that share almost identical folds and extensive structural similarity in their catalytic core. Helicases are involved in ATP-dependent RNA or DNA unwinding. Two distinct types of helicases exist, those forming toroidal, predominantly hexameric structures, and those that do not. SF1 and SF2 helicases do not form toroidal structures, while SF3-6 helicases do. Their conserved helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350171 [Multi-domain] Cd Length: 59 Bit Score: 47.16 E-value: 5.91e-07
10 20 30
....*....|....*....|....*....|....*..
gi 504995345 642 LGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFF 678
Cdd:cd09300 22 PELNTIIVDKNLRSYRGLNQAFGRANRIYTFGGIVTY 58
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
98-228 |
6.22e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 42.09 E-value: 6.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 504995345 98 HKGQIAEMKTGEGKTLVSTLPAYLNALSGKGVHVV-------TVNDyLARRDAEWMGqvhrYLGLSVGLIQSGMGPAERQ 170
Cdd:smart00487 24 LRDVILAAPTGSGKTLAALLPALEALKRGKGGRVLvlvptreLAEQ-WAEELKKLGP----SLGLKVVGLYGGDSKREQL 98
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 504995345 171 R---NYACDITYATnselgFDYLRDNMAtvMSDVVQRPFNYCVIDEVDsVLIDEARTPLII 228
Cdd:smart00487 99 RkleSGKTDILVTT-----PGRLLDLLE--NDKLSLSNVDLVILDEAH-RLLDGGFGDQLE 151
|
|
| SF2_C |
cd18785 |
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases ... |
618-679 |
4.02e-03 |
|
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases include DEAD-box helicases, UvrB, RecG, Ski2, Sucrose Non-Fermenting (SNF) family helicases, and dicer proteins, among others. Similar to SF1 helicases, they do not form toroidal structures like SF3-6 helicases. SF2 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350172 [Multi-domain] Cd Length: 77 Bit Score: 36.91 E-value: 4.02e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 504995345 618 REVYKAIRKEYEHLTSREHDE--VVKLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTKFFL 679
Cdd:cd18785 13 IEHAEEIASSLEILVATNVLGegIDVPSLDTVIFFDPPSSAASYIQRVGRAGRGGKDEGEVILF 76
|
|
| |
