|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
8-473 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 724.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 8 HRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKGE 87
Cdd:COG0469 3 RRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKVILIPNSIKENiANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFPN 167
Cdd:COG0469 83 VELKKGDTFTLTTDDVEGD-AERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 168 LNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKECDGMMVA 247
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 248 RGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYPIA 327
Cdd:COG0469 242 RGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPVE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 328 AIKTMASIAEEIEPEVQFINY-----PPAEKTETHALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIVAFTP 402
Cdd:COG0469 322 AVETMARIAEEAEKSLDYRRIldrlrDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALTP 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505043146 403 SLVVYHRLNLIWGVKPLLLqPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKGTNFLKIHTV 473
Cdd:COG0469 402 NERTARRLALVWGVYPVLV-DDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
7-464 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 569.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 7 SHRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKG 86
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 87 EITLNAGEKVILIPNSIKENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFP 166
Cdd:PRK05826 83 KITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 167 NLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLkfREAN---IPVIAKIEKPQAIENFDELVKECDG 243
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLL--REAGcphAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 244 MMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGN 323
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 324 YPIAAIKTMASIAEEIEPEV------QFINYPPAEKTETHALSeSLNCIDKIINLRCIACFTTTGYTARIASDERPKAPI 397
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKEFsinlskHRLDRQFDRIDEAIAMS-AMYAANHLKGVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505043146 398 VAFTPSLVVYHRLNLIWGVKPLLLQPQEEGlEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKG 464
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADT-DDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAGG 465
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
8-470 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 568.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 8 HRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKGE 87
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKVILIPNSIK-ENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFP 166
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKgEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 167 NLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREA-NIPVIAKIEKPQAIENFDELVKECDGMM 245
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAkDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 246 VARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYP 325
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 326 IAAIKTMASIAEEIEPEVQFINYPPAEK-------TETHALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIV 398
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKnsdpkpsTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505043146 399 AFTPSLVVYHRLNLIWGVKPLLLQPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKGTNFLKI 470
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
9-473 |
2.09e-160 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 462.94 E-value: 2.09e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKG-E 87
Cdd:cd00288 3 RTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGkD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKVILIPN-SIKENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEV-GKIEGTQVYCRVITGGILKSRKGVNF 165
Cdd:cd00288 83 ISLKAGDKFLVTTDpAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVlSKDDDKTLVCEVLNGGVLGSRKGVNL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 166 PNLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKECDGMM 245
Cdd:cd00288 163 PGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 246 VARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYP 325
Cdd:cd00288 243 VARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 326 IAAIKTMASIAEEIE---PEVQFIN------YPPAEKTETHALS---ESLNCidkiiNLRCIACFTTTGYTARIASDERP 393
Cdd:cd00288 323 VEAVKAMARICLEAEkalSHRVLFNemrrltPRPTSTTEAVAMSavrAAFEL-----GAKAIVVLTTSGRTARLVSKYRP 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 394 KAPIVAFTPSLVVYHRLNLIWGVKPLL----LQPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKgTNFLK 469
Cdd:cd00288 398 NAPIIAVTRNEQTARQLHLYRGVYPVLfeepKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSGS-TNTMR 476
|
....
gi 505043146 470 IHTV 473
Cdd:cd00288 477 ILTV 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
9-347 |
2.98e-137 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 399.05 E-value: 2.98e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKG-- 86
Cdd:pfam00224 3 RTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGkk 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 87 EITLNAGEKVILipnSIKENIA-----NCIPIDYPHLAEDAQPGAQVLLDDGNLELEV-GKIEGTQVYCRVITGGILKSR 160
Cdd:pfam00224 83 DIELKAGDEMIV---STDAKYKgacddEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVlSKDDDKTLVVEVLNGGVIGSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 161 KGVNFPNLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKE 240
Cdd:pfam00224 160 KGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 241 CDGMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESA 320
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*..
gi 505043146 321 MGNYPIAAIKTMASIAEEIEPEVQFIN 347
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRN 346
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
8-473 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 724.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 8 HRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKGE 87
Cdd:COG0469 3 RRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEGP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKVILIPNSIKENiANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFPN 167
Cdd:COG0469 83 VELKKGDTFTLTTDDVEGD-AERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 168 LNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKECDGMMVA 247
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 248 RGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYPIA 327
Cdd:COG0469 242 RGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPVE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 328 AIKTMASIAEEIEPEVQFINY-----PPAEKTETHALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIVAFTP 402
Cdd:COG0469 322 AVETMARIAEEAEKSLDYRRIldrlrDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALTP 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505043146 403 SLVVYHRLNLIWGVKPLLLqPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKGTNFLKIHTV 473
Cdd:COG0469 402 NERTARRLALVWGVYPVLV-DDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
7-464 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 569.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 7 SHRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKG 86
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 87 EITLNAGEKVILIPNSIKENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFP 166
Cdd:PRK05826 83 KITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 167 NLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLkfREAN---IPVIAKIEKPQAIENFDELVKECDG 243
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLL--REAGcphAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 244 MMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGN 323
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 324 YPIAAIKTMASIAEEIEPEV------QFINYPPAEKTETHALSeSLNCIDKIINLRCIACFTTTGYTARIASDERPKAPI 397
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKEFsinlskHRLDRQFDRIDEAIAMS-AMYAANHLKGVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505043146 398 VAFTPSLVVYHRLNLIWGVKPLLLQPQEEGlEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKG 464
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADT-DDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAGG 465
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
8-470 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 568.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 8 HRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKGE 87
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKVILIPNSIK-ENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFP 166
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKgEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 167 NLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREA-NIPVIAKIEKPQAIENFDELVKECDGMM 245
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAkDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 246 VARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYP 325
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 326 IAAIKTMASIAEEIEPEVQFINYPPAEK-------TETHALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIV 398
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKnsdpkpsTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505043146 399 AFTPSLVVYHRLNLIWGVKPLLLQPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKGTNFLKI 470
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-474 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 560.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 1 MSVNSFSHRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRV 80
Cdd:PRK06354 1 MSLRDLMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 81 GQLPKGEITLNAGEKVILIPNSIKENiANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQ--VYCRVITGGILK 158
Cdd:PRK06354 81 GRFEDGPIELKTGDEFILTSREVLGT-QEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADgeLHCKVLVGGVLS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 159 SRKGVNFPNLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREA-NIPVIAKIEKPQAIENFDEL 237
Cdd:PRK06354 160 NKKGVNFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNGkHIPIIAKIEKQEAIDNIDAI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 238 VKECDGMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSG 317
Cdd:PRK06354 240 LELCDGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 318 ESAMGNYPIAAIKTMASIAEEIEPEVQFINYPPAEKTE----THALSESLNCIDKIINLRCIACFTTTGYTARIASDERP 393
Cdd:PRK06354 320 ETAAGDYPVEAVQTMATIAVRIEKDLPYRDILSKRPEFtttiTNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 394 KAPIVAFTPSLVVYHRLNLIWGVKPLLLQPQEEGLEVLITEMESClLQRNLVASGDKILILGGSPIQQAKGTNFLKIHTV 473
Cdd:PRK06354 400 KTPILAVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVA-QESGLLKQGDLVVITAGTLVGESGSTDLMKVHVV 478
|
.
gi 505043146 474 S 474
Cdd:PRK06354 479 G 479
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
9-476 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 537.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKGEI 88
Cdd:PRK06247 6 RVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGKV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 89 TLNAGEKVILIPNSIkENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFPNL 168
Cdd:PRK06247 86 QLANGQTFRLDVDDA-PGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLPGT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 169 NLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFReanIPVIAKIEKPQAIENFDELVKECDGMMVAR 248
Cdd:PRK06247 165 VLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGR---VPVMAKIEKPQAIDRLEAIVEASDAIMVAR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 249 GDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYPIAA 328
Cdd:PRK06247 242 GDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVEA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 329 IKTMASIAEEIEPEVQF-----INYPPAEKTETHALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIVAFTPS 403
Cdd:PRK06247 322 VRTMARIIRQVERDPTYpplihAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTPN 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505043146 404 LVVYHRLNLIWGVKPLLLqPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKGTNFLKIHTVSRE 476
Cdd:PRK06247 402 PETARRLALTWGVHCVVV-DDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYIGED 473
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
9-473 |
2.09e-160 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 462.94 E-value: 2.09e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKG-E 87
Cdd:cd00288 3 RTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGkD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKVILIPN-SIKENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEV-GKIEGTQVYCRVITGGILKSRKGVNF 165
Cdd:cd00288 83 ISLKAGDKFLVTTDpAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVlSKDDDKTLVCEVLNGGVLGSRKGVNL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 166 PNLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKECDGMM 245
Cdd:cd00288 163 PGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 246 VARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYP 325
Cdd:cd00288 243 VARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 326 IAAIKTMASIAEEIE---PEVQFIN------YPPAEKTETHALS---ESLNCidkiiNLRCIACFTTTGYTARIASDERP 393
Cdd:cd00288 323 VEAVKAMARICLEAEkalSHRVLFNemrrltPRPTSTTEAVAMSavrAAFEL-----GAKAIVVLTTSGRTARLVSKYRP 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 394 KAPIVAFTPSLVVYHRLNLIWGVKPLL----LQPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKgTNFLK 469
Cdd:cd00288 398 NAPIIAVTRNEQTARQLHLYRGVYPVLfeepKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSGS-TNTMR 476
|
....
gi 505043146 470 IHTV 473
Cdd:cd00288 477 ILTV 480
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
9-473 |
4.92e-138 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 405.59 E-value: 4.92e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKG-E 87
Cdd:PRK09206 3 KTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGGnD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKVILIPN-SIKENiANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFP 166
Cdd:PRK09206 83 VSLKAGQTFTFTTDkSVVGN-KERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 167 NLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREA-NIPVIAKIEKPQAIENFDELVKECDGMM 245
Cdd:PRK09206 162 GVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGeNIQIISKIENQEGLNNFDEILEASDGIM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 246 VARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYP 325
Cdd:PRK09206 242 VARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 326 IAAIKTMASIAEE----IEPEVQFINYPPaEKTETHALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIVAFT 401
Cdd:PRK09206 322 LEAVSIMATICERtdrvMNSRLESNNDNR-KLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505043146 402 PSLVVYHRLNLIWGVKPLLLQPQEEGLEVLITEMESClLQRNLVASGDKILILGGSPIQQAKgTNFLKIHTV 473
Cdd:PRK09206 401 TNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELA-LQSGLAQKGDVVVMVSGALVPSGT-TNTASVHVL 470
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
9-347 |
2.98e-137 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 399.05 E-value: 2.98e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKG-- 86
Cdd:pfam00224 3 RTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGkk 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 87 EITLNAGEKVILipnSIKENIA-----NCIPIDYPHLAEDAQPGAQVLLDDGNLELEV-GKIEGTQVYCRVITGGILKSR 160
Cdd:pfam00224 83 DIELKAGDEMIV---STDAKYKgacddEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVlSKDDDKTLVVEVLNGGVIGSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 161 KGVNFPNLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKE 240
Cdd:pfam00224 160 KGVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 241 CDGMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESA 320
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*..
gi 505043146 321 MGNYPIAAIKTMASIAEEIEPEVQFIN 347
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRN 346
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
9-454 |
2.18e-124 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 372.00 E-value: 2.18e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKGE- 87
Cdd:PLN02461 22 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGKp 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 88 ITLNAGEKV-ILIPNSIKENiANCIPIDYPHLAEDAQPGAQVLLDDGNLELEV---GKIEGTqVYCRVITGGILKSRKGV 163
Cdd:PLN02461 102 VQLKQGQEItITTDYSIKGD-ENMIAMSYKKLAVDVKPGSVILCADGTITLTVlscDVEAGT-VRCRCENSAMLGERKNV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 164 NFPNLNLSLPSLTAKDQED-LEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKECD 242
Cdd:PLN02461 180 NLPGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDILAESD 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 243 GMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMG 322
Cdd:PLN02461 260 AFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAG 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 323 NYPIAAIKTMASIAEEIEpevQFINYP------------PAEKTETHAlSESLNCIDKiINLRCIACFTTTGYTARIASD 390
Cdd:PLN02461 340 AYPELAVKTMARICREAE---ASLDYGalfkeimrsaplPMSPLESLA-SSAVRTANK-VKASLIVVLTRGGTTARLVAK 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 391 ERPKAPIVaftpSLVV-----------------YHRLNLIWGVKPLLLQPQEEGLEVLITE--MESCL---LQRNLVASG 448
Cdd:PLN02461 415 YRPAVPIL----SVVVpeittdsfdwscsdeapARHSLIYRGLIPVLAEGSAKATDSESTEeiLEAAIehaKKKGLCKPG 490
|
....*.
gi 505043146 449 DKILIL 454
Cdd:PLN02461 491 DSVVAL 496
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
7-473 |
2.38e-116 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 351.37 E-value: 2.38e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 7 SHRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHP-ITLLQDLQGPKIRVGQLPK 85
Cdd:PTZ00066 37 QKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARPNAnLGILLDTKGPEIRTGFLKN 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 86 G-EITLNAGEKVILIPNSIKENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVN 164
Cdd:PTZ00066 117 HkPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMN 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 165 FPNLNLSLPSLTAKDQED-LEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKECDG 243
Cdd:PTZ00066 197 LPGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDG 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 244 MMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGN 323
Cdd:PTZ00066 277 IMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGK 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 324 YPIAAIKTMASIAEEIEPEVQF---------INYPPAEKTETHALSESLNCIDkiINLRCIACFTTTGYTARIASDERPK 394
Cdd:PTZ00066 357 FPVEAVNIMAKICFEAETCIDYrvlyhaihlAVPTPVSVQEAVARSAVETAED--INAKLIIALTETGNTARLISKYRPS 434
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505043146 395 APIVAFTPSLVVYHRLNLIWGVKPLLLqPQEEGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKGTNFLKIHTV 473
Cdd:PTZ00066 435 CTILALSASPSVVKSLSVARGVTTYVV-NSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNLMKVVKI 512
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
2-473 |
2.77e-114 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 348.46 E-value: 2.77e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 2 SVNSFSHRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTE-LDHPITLLQDLQGPKIRV 80
Cdd:PLN02623 104 SKPSVRRKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQsKDNVIAIMLDTKGPEVRS 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 81 GQLPKgEITLNAGEKVILipnSIKENI--ANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILK 158
Cdd:PLN02623 184 GDLPQ-PIMLEEGQEFTF---TIKRGVstEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELK 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 159 SRKGVNFPNLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELV 238
Cdd:PLN02623 260 SRRHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSII 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 239 KECDGMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGE 318
Cdd:PLN02623 340 TASDGAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGE 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 319 SAMGNYPIAAIKTMASIAEEIEPEVQFINYPP----------AEKTETHA--LSESLNCidkiinlrCIACFTTTGYTAR 386
Cdd:PLN02623 420 TAHGKFPLKAVKVMHTVALRTEATLPEGTTPPnlgqafknhmSEMFAFHAtmMANTLGT--------SIIVFTRTGFMAI 491
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 387 IASDERPKAPIVAFTPSLVVYHRLNLIWGVKPLLLQPQEEGLEVLITEMeSCLLQRNLVASGDKILIL--GGSPIQQAKG 464
Cdd:PLN02623 492 LLSHYRPSGTIFAFTNEKRIQQRLALYQGVCPIYMQFSDDAEETFARAL-SLLLNKGMVKEGEEVALVqsGRQPIWRSES 570
|
....*....
gi 505043146 465 TNFLKIHTV 473
Cdd:PLN02623 571 THHIQVRKV 579
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
13-340 |
2.75e-103 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 312.26 E-value: 2.75e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 13 VATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHgRTIERLRKistELDHPITLLQDLQGPKIRVGQLPKGEITLNA 92
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESH-KDIIRLVK---SLDDSIKILGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 93 GEKVILIPNSIKENIANCiPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNFPNLNLSL 172
Cdd:PRK06739 82 GDSFILHTQPVTGSSTEA-SVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 173 PSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFLKFREANIP-VIAKIEKPQAIENFDELVKECDGMMVARGDL 251
Cdd:PRK06739 161 PAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPnLIAKIETMEAIENFQDICKEADGIMIARGDL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 252 GVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYPIAAIKT 331
Cdd:PRK06739 241 GVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVST 320
|
....*....
gi 505043146 332 MASIAEEIE 340
Cdd:PRK06739 321 LRLVSEFAE 329
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
34-454 |
1.38e-101 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 311.60 E-value: 1.38e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 34 MNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLPKGEITLNAGEKVILI--PNSIKENIANCI 111
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTtdPAFADKGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 112 PIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQ-VYCRVITGGILKSRKGVNFPNLNLSLPSLTAKDQEDLEFGIAQE 190
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQtLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 191 IDWVCLSFVRGVEDIHCLKDFLKFREANIPVIAKIEKPQAIENFDELVKECDGMMVARGDLGVEMRPEKVPLLQKKIIQS 270
Cdd:PTZ00300 161 VDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 271 CNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYPIAAIKTMASIAEEIEPEVQ---FIN 347
Cdd:PTZ00300 241 CNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNeyvFFN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 348 -----YPPAEKTETHALSESLNCIDKiINLRCIACFTTTGYTARIASDERPKAPIVAFTPSLVVYHRLNLIWGVKPLLLQ 422
Cdd:PTZ00300 321 sikklQPIPMSAEEAVCSSAVNSVYE-TKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVFFD 399
|
410 420 430
....*....|....*....|....*....|....*.
gi 505043146 423 PQ----EEGLEVLITEMESCLLQRNLVASGDKILIL 454
Cdd:PTZ00300 400 AErlghDEGKEQRVAMGVGFAKSKGYVQSGDLMVVV 435
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
9-454 |
3.39e-101 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 312.45 E-value: 3.39e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQLpKGEI 88
Cdd:PLN02762 26 RTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDL-GGAS 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 89 TLNA--GEKVILIPNSIKENIANC-IPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVITGGILKSRKGVNF 165
Cdd:PLN02762 105 SAKAedGEEWTFTVRKFDGSRPEFtIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPGLLLPRANLTF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 166 -------PNLNLSLPSLTAKDQEDLEFGIAQEIDWVCLSFVRGVEDIHCLKDFL--KFREANIPVIAKIEKPQAIENFDE 236
Cdd:PLN02762 185 wrdgslvRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIaaRSRDSDIGVIAKIESLDSLKNLEE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 237 LVKECDGMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLS 316
Cdd:PLN02762 265 IIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRADALMLS 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 317 GESAMGNYPIAAIKTMASIAEEIEPEVQFINYppAEKTETHALSESL---------NCIDKIIN---LRCIACFTTTGYT 384
Cdd:PLN02762 345 GESAMGLYPEKALSVLRSVSLRMELWSREEKR--HEALELPQLSSSLsdriseeicNSAAKMANnlgVDAIFVYTKHGHM 422
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 385 ARIASDERPKAPIVAFTPSLVVYHRLNLIWGVKPLLLqPQEEGLEVLITEMESCLLQRNLVASGDKILIL 454
Cdd:PLN02762 423 ASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRL-DFSDDMESNLNKTFSLLKARGMIKSGDLVIAV 491
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
5-453 |
6.36e-91 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 286.18 E-value: 6.36e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 5 SFSHRTKIVATIGPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKI--STELDHPITLlqDLQGPKIRVGQ 82
Cdd:PLN02765 25 FFPALTKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAvkNTKKLCAVML--DTVGPELQVIN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 83 LPKGEITLNAGEKVILIPNSIKENIANCIPIDYPHLAEDAQPGAQVLL--------DDGNLELEVGKIEGTQVYCRVITG 154
Cdd:PLN02765 103 KTEKPISLKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKNS 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 155 GILKsrkGVNFP----NLNLSLPSLTAKDQEDLE-FGIAQEIDWVCLSFVRGVEDIHCLKDFLKfrEANIP---VIAKIE 226
Cdd:PLN02765 183 ATLA---GSLFTlhvsQVRIDLPTLSEKDKEVIStWGVPNKIDFLSLSYTRHAEDVREAREFLS--SLGLSqtqIFAKIE 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 227 KPQAIENFDELVKECDGMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITaTQMLESMINSPRPTRAEASDVANAI 306
Cdd:PLN02765 258 NVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAV 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 307 IDGTDAIMLSGESAMGNYPIAAIKTMASIAEEIEPEVQFINY---------PPAEKTETHALSESLNCIDkiINLRCIAC 377
Cdd:PLN02765 337 LDGADAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYfkktvkyvgEPMSHLESIASSAVRAAIK--VKASVIIV 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 378 FTTTGYTARIASDERPKAPIVAftpslVVYHRL---NLIW---------------GVKPLLLQPQEEGLEVLITEmESCL 439
Cdd:PLN02765 415 FTSSGRAARLIAKYRPTMPVLS-----VVIPRLktnQLKWsftgafqarqclivrGLFPMLADPRHSAESTSATN-ESVL 488
|
490 500
....*....|....*....|.
gi 505043146 440 -------LQRNLVASGDKILI 453
Cdd:PLN02765 489 kvaldhgKAAGVIKSHDRVVV 509
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
9-305 |
7.79e-60 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 204.09 E-value: 7.79e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 9 RTKIVATI-GPASQSEMVIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQL--PK 85
Cdd:PRK08187 134 RTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVagPL 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 86 GEITLNAGEKVIL---IPNSIKENIANCIPIDYPHLAEDAQPGAQVLLDDGNLELEVGKIEGTQVYCRVI----TGGILK 158
Cdd:PRK08187 214 GKTRLYTGDRLALvaqGPPRRIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTharpKGLKLK 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 159 SRKGVNFPNLNLSLPSLTAKDQEDLEFgIAQEIDWVCLSFVRGVEDIHCLKDFLKFREAN----IPVIAKIEKPQAIENF 234
Cdd:PRK08187 294 PEKGLNFPDTALDLPALTEKDRADLDF-VARHADLVGYSFVQSPGDVEALQAALAARRPDdwrkLGLVLKIETPRAVANL 372
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505043146 235 DELVKECDG-----MMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPTRAEASDVANA 305
Cdd:PRK08187 373 PELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA 448
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
271-474 |
2.04e-52 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 179.71 E-value: 2.04e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 271 CNKKGIPVITATQMLESMINSPRPTRAEASDVANAIIDGTDAIMLSGESAMGNYPIAAIKTMASIAEEIE--PEVQFINY 348
Cdd:COG3848 2 CNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEedLEYREQRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 349 PPA---EKTETHALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIVAFTPSLVVYHRLNLIWGVKPlLLQPQE 425
Cdd:COG3848 82 PRAkesSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYP-LLVEES 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 505043146 426 EGLEVLITEMESCLLQRNLVASGDKILILGGSPIQQAKGTNFLKIHTVS 474
Cdd:COG3848 161 ASTDEMFAVAVALALEAGLVKDGDLVVITAGVPVGVSGTTNLLKVHVVG 209
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
25-340 |
6.61e-46 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 168.59 E-value: 6.61e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 25 VIRELVKAGMNVARLNFSHGSYDDHGRTIERLRKISTELDHPITLLQDLQGPKIRVGQL--------------------- 83
Cdd:PRK14725 157 LVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGPIapgprviklrptrdalgrvlt 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 84 --------------------------PKGEITLNAGEKVIL--------------------------------------- 98
Cdd:PRK14725 237 parlwltasespppspppgpvglpvdPEWLARLEPGDELRFtdargkkrkltvtevddegvlaegsqtaylangtllrlg 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 99 ------------IPNSIKENI-------ANCIPID--------------YPHLAEDAQPGAQVLLDDGNLELEVGKIEGT 145
Cdd:PRK14725 317 rhdstrvgglppVEQKLRLKVgdrlvltRDDAPGDpaqgdapparisctLPEAFRAARVGERVWFDDGKIGAVVVKVEAD 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 146 QVYCRVI----TGGILKSRKGVNFPNLNLSLPSLTAKDQEDLEFgIAQEIDWVCLSFVRGVEDIHCLKDFL-KFREANIP 220
Cdd:PRK14725 397 EVELRITharpGGSKLKAGKGINLPDSHLPLPALTDKDLEDLAF-VAKHADIVALSFVRSPEDVRLLLDALeKLGADDLG 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 221 VIAKIEKPQAIENFDELVKE-----CDGMMVARGDLGVEMRPEKVPLLQKKIIQSCNKKGIPVITATQMLESMINSPRPT 295
Cdd:PRK14725 476 VVLKIETRRAFENLPRILLEamrhpRFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKGLPS 555
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 505043146 296 RAEASDVANAIidGTDAIMLSgesaMGNYPIAAIKTMASIAEEIE 340
Cdd:PRK14725 556 RAEITDAAMAL--RAECVMLN----KGPHIVEAVRVLDDILRRME 594
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
357-471 |
1.92e-31 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 116.81 E-value: 1.92e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505043146 357 HALSESLNCIDKIINLRCIACFTTTGYTARIASDERPKAPIVAFTPSLVVYHRLNLIWGVKPLLLqPQEEGLEVLITEME 436
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLF-DEAETTDEMLRRAV 79
|
90 100 110
....*....|....*....|....*....|....*
gi 505043146 437 SCLLQRNLVASGDKILILGGSPIQQAKGTNFLKIH 471
Cdd:pfam02887 80 KVAKEAGLVKKGDLVVITAGVPFGVSGTTNTLKVI 114
|
|
| |
