|
Name |
Accession |
Description |
Interval |
E-value |
| Adk |
COG0563 |
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ... |
9-220 |
6.70e-78 |
|
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440329 [Multi-domain] Cd Length: 212 Bit Score: 233.10 E-value: 6.70e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 9 HVVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR-L 87
Cdd:COG0563 2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANgF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 88 LFDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRP 167
Cdd:COG0563 82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 505062433 168 DDTADVIEVRQRIYNEHGLPILAHYREHapDRFRTVNGEQSYEAVYAETCRAL 220
Cdd:COG0563 162 DDNEETVRKRLEVYHEQTAPLIDYYRKK--GKLVEIDGEGSIEEVTADILAIL 212
|
|
| adk |
PRK00279 |
adenylate kinase; Reviewed |
10-221 |
1.42e-62 |
|
adenylate kinase; Reviewed
Pssm-ID: 234711 [Multi-domain] Cd Length: 215 Bit Score: 194.21 E-value: 1.42e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR-LL 88
Cdd:PRK00279 3 LILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNgFL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRPD 168
Cdd:PRK00279 83 LDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRAD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYREHapDRFRTVNGEQSYEAVYAETCRALG 221
Cdd:PRK00279 163 DNEETVRKRLEVYHKQTAPLIDYYKKK--GKLKKIDGTGSIDEVFADILKALG 213
|
|
| adk |
TIGR01351 |
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ... |
10-215 |
7.45e-59 |
|
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273569 [Multi-domain] Cd Length: 210 Bit Score: 184.36 E-value: 7.45e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPG--TDRL 87
Cdd:TIGR01351 2 LVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDdnENGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 88 LFDGFPRTMGQVPILakfEQILNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRP 167
Cdd:TIGR01351 82 ILDGFPRTLSQAEAL---DALLEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQRE 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 505062433 168 DDTADVIEVRQRIYNEHGLPILAHYREHApdRFRTVNGEQSYEAVYAE 215
Cdd:TIGR01351 159 DDTEEVVKKRLEVYKEQTEPLIDYYKKRG--ILVQIDGNGPIDEVWKR 204
|
|
| ADK |
cd01428 |
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ... |
10-212 |
1.97e-54 |
|
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.
Pssm-ID: 238713 [Multi-domain] Cd Length: 194 Bit Score: 172.81 E-value: 1.97e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKT-PGTDRLL 88
Cdd:cd01428 2 ILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKpDCKKGFI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKFEQIlNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLvnqpprvpERCDRDGTALEQRPD 168
Cdd:cd01428 82 LDGFPRTVDQAEALDELLDE-GIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYREhaPDRFRTVNGEQSYEAV 212
Cdd:cd01428 153 DNEETIKKRLEVYKEQTAPLIDYYKK--KGKLVEIDGSGDIDEV 194
|
|
| ADK |
pfam00406 |
Adenylate kinase; |
12-195 |
5.44e-53 |
|
Adenylate kinase;
Pssm-ID: 395329 [Multi-domain] Cd Length: 184 Bit Score: 168.64 E-value: 5.44e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 12 IFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGT-DRLLFD 90
Cdd:pfam00406 1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCkNGFLLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 91 GFPRTMGQVpilAKFEQIL--NFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRPD 168
Cdd:pfam00406 81 GFPRTVPQA---EALEELLerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSD 157
|
170 180
....*....|....*....|....*..
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYREH 195
Cdd:pfam00406 158 DNEETVKKRLETYHKQTKPLIDYYKKK 184
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
6-90 |
5.48e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 36.20 E-value: 5.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 6 PPTHVVIFGRPGSGKSSLAEQLGA-----DHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLK 80
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARelgppGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD 80
|
90
....*....|
gi 505062433 81 TpgtdrLLFD 90
Cdd:smart00382 81 V-----LILD 85
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adk |
COG0563 |
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ... |
9-220 |
6.70e-78 |
|
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440329 [Multi-domain] Cd Length: 212 Bit Score: 233.10 E-value: 6.70e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 9 HVVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR-L 87
Cdd:COG0563 2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANgF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 88 LFDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRP 167
Cdd:COG0563 82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 505062433 168 DDTADVIEVRQRIYNEHGLPILAHYREHapDRFRTVNGEQSYEAVYAETCRAL 220
Cdd:COG0563 162 DDNEETVRKRLEVYHEQTAPLIDYYRKK--GKLVEIDGEGSIEEVTADILAIL 212
|
|
| adk |
PRK00279 |
adenylate kinase; Reviewed |
10-221 |
1.42e-62 |
|
adenylate kinase; Reviewed
Pssm-ID: 234711 [Multi-domain] Cd Length: 215 Bit Score: 194.21 E-value: 1.42e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR-LL 88
Cdd:PRK00279 3 LILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNgFL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRPD 168
Cdd:PRK00279 83 LDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRAD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYREHapDRFRTVNGEQSYEAVYAETCRALG 221
Cdd:PRK00279 163 DNEETVRKRLEVYHKQTAPLIDYYKKK--GKLKKIDGTGSIDEVFADILKALG 213
|
|
| adk |
TIGR01351 |
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ... |
10-215 |
7.45e-59 |
|
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273569 [Multi-domain] Cd Length: 210 Bit Score: 184.36 E-value: 7.45e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPG--TDRL 87
Cdd:TIGR01351 2 LVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDdnENGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 88 LFDGFPRTMGQVPILakfEQILNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRP 167
Cdd:TIGR01351 82 ILDGFPRTLSQAEAL---DALLEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQRE 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 505062433 168 DDTADVIEVRQRIYNEHGLPILAHYREHApdRFRTVNGEQSYEAVYAE 215
Cdd:TIGR01351 159 DDTEEVVKKRLEVYKEQTEPLIDYYKKRG--ILVQIDGNGPIDEVWKR 204
|
|
| ADK |
cd01428 |
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ... |
10-212 |
1.97e-54 |
|
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.
Pssm-ID: 238713 [Multi-domain] Cd Length: 194 Bit Score: 172.81 E-value: 1.97e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKT-PGTDRLL 88
Cdd:cd01428 2 ILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKpDCKKGFI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKFEQIlNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLvnqpprvpERCDRDGTALEQRPD 168
Cdd:cd01428 82 LDGFPRTVDQAEALDELLDE-GIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYREhaPDRFRTVNGEQSYEAV 212
Cdd:cd01428 153 DNEETIKKRLEVYKEQTAPLIDYYKK--KGKLVEIDGSGDIDEV 194
|
|
| ADK |
pfam00406 |
Adenylate kinase; |
12-195 |
5.44e-53 |
|
Adenylate kinase;
Pssm-ID: 395329 [Multi-domain] Cd Length: 184 Bit Score: 168.64 E-value: 5.44e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 12 IFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGT-DRLLFD 90
Cdd:pfam00406 1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCkNGFLLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 91 GFPRTMGQVpilAKFEQIL--NFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRPD 168
Cdd:pfam00406 81 GFPRTVPQA---EALEELLerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSD 157
|
170 180
....*....|....*....|....*..
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYREH 195
Cdd:pfam00406 158 DNEETVKKRLETYHKQTKPLIDYYKKK 184
|
|
| PRK14530 |
PRK14530 |
adenylate kinase; Provisional |
9-215 |
1.79e-37 |
|
adenylate kinase; Provisional
Pssm-ID: 237747 [Multi-domain] Cd Length: 215 Bit Score: 129.91 E-value: 1.79e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 9 HVVIFGRPGSGK----SSLAEQLGADHgfllIRTGELLRnAIRKGDPLGVRAE-----QLIKGGNLVPDSLIGELLEQTL 79
Cdd:PRK14530 5 RILLLGAPGAGKgtqsSNLAEEFGVEH----VTTGDALR-ANKQMDISDMDTEydtpgEYMDAGELVPDAVVNEIVEEAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 80 KTpgTDRLLFDGFPRTMGQVPILAKFEQIlnfriDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRD 159
Cdd:PRK14530 80 SD--ADGFVLDGYPRNLEQAEYLESITDL-----DVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDEC 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 505062433 160 GTALEQRPDDTADVIEVRQRIYNEHGLPILAHYREHapDRFRTVNGEQSYEAVYAE 215
Cdd:PRK14530 153 GGELIQRDDDTEETVRERLDVFEENTEPVIEHYRDQ--GVLVEVDGEQTPDEVWAD 206
|
|
| PLN02674 |
PLN02674 |
adenylate kinase |
6-220 |
7.43e-33 |
|
adenylate kinase
Pssm-ID: 178279 [Multi-domain] Cd Length: 244 Bit Score: 118.83 E-value: 7.43e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 6 PPTHVVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTD 85
Cdd:PLN02674 30 PDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 86 R-LLFDGFPRTMGQVPIL--------AKFEQILNFRI-DCYLEiavsheaavKRMTGRRVCPVCGSTYHLVNQPPRVPER 155
Cdd:PLN02674 110 KgFILDGFPRTVVQAQKLdemlakqgAKIDKVLNFAIdDAILE---------ERITGRWIHPSSGRTYHTKFAPPKVPGV 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505062433 156 CDRDGTALEQRPDDTADVIEVRQRIYNEHGLPILAHYREHApdRFRTVNGEQSYEAVYAETCRAL 220
Cdd:PLN02674 181 DDVTGEPLIQRKDDTAAVLKSRLEAFHKQTEPVIDYYAKKG--VVANLHAEKPPKEVTAEVQKAL 243
|
|
| PRK14526 |
PRK14526 |
adenylate kinase; Provisional |
10-212 |
5.12e-32 |
|
adenylate kinase; Provisional
Pssm-ID: 172992 [Multi-domain] Cd Length: 211 Bit Score: 115.72 E-value: 5.12e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKT-PGTDRLL 88
Cdd:PRK14526 3 LVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTiKNNDNFI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKF---EQILNFRIDcyleiavsHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQ 165
Cdd:PRK14526 83 LDGFPRNINQAKALDKFlpnIKIINFLID--------EELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQ 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 505062433 166 RPDDTADVIEVRQRIYNEHGLPILAHYREHapDRFRTVNGEQSYEAV 212
Cdd:PRK14526 155 RKDDKEESLKTRLQEYKLQTKPLIEFYSKC--NRLNNIDASKDIDEV 199
|
|
| PRK14532 |
PRK14532 |
adenylate kinase; Provisional |
10-221 |
2.75e-31 |
|
adenylate kinase; Provisional
Pssm-ID: 184729 [Multi-domain] Cd Length: 188 Bit Score: 113.38 E-value: 2.75e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTL-KTPGTDRLL 88
Cdd:PRK14532 3 LILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLpEAEAAGGAI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRrvcpvcgstyhlvnqpprvpercdrdgTALEQRPD 168
Cdd:PRK14532 83 FDGFPRTVAQAEALDKMLASRGQKIDVVIRLKVDDEALIERIVKR---------------------------FEEQGRPD 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYREHApdRFRTVNGEQSYEAVYAETCRALG 221
Cdd:PRK14532 136 DNPEVFVTRLDAYNAQTAPLLPYYAGQG--KLTEVDGMGSIEAVAASIDAALE 186
|
|
| PTZ00088 |
PTZ00088 |
adenylate kinase 1; Provisional |
7-193 |
1.91e-30 |
|
adenylate kinase 1; Provisional
Pssm-ID: 240262 [Multi-domain] Cd Length: 229 Bit Score: 112.20 E-value: 1.91e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 7 PTHVVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR 86
Cdd:PTZ00088 6 PLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVTDDC 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 87 ---LLFDGFPRTMGQVPILAKFEqilnfRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVN-------QPPRVP--- 153
Cdd:PTZ00088 86 fkgFILDGFPRNLKQCKELGKIT-----NIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIAHirsdpydMPPILPpad 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 505062433 154 -ERCdRDGTALEQRPDDTADVIEVRQRIYNEHGLPILAHYR 193
Cdd:PTZ00088 161 cEGC-KGNPKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFK 200
|
|
| PLN02842 |
PLN02842 |
nucleotide kinase |
11-216 |
3.26e-30 |
|
nucleotide kinase
Pssm-ID: 178435 [Multi-domain] Cd Length: 505 Bit Score: 116.50 E-value: 3.26e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 11 VIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR--LL 88
Cdd:PLN02842 1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDAKEkgWL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKfeqiLNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHLVNQPPRVPERCDRdgtaLEQRPD 168
Cdd:PLN02842 81 LDGYPRSFAQAQSLEK----LKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPESEEIKAR----LITRPD 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYRehapDRFRTVNGEQSYEAVYAET 216
Cdd:PLN02842 153 DTEEKVKARLQIYKKNAEAILSTYS----DIMVKIDGNRPKEVVFEEI 196
|
|
| adk |
PRK02496 |
adenylate kinase; Provisional |
8-221 |
1.87e-29 |
|
adenylate kinase; Provisional
Pssm-ID: 179433 [Multi-domain] Cd Length: 184 Bit Score: 108.30 E-value: 1.87e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 8 THVVIFGRPGSGKS----SLAEQLGADHgfllIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPG 83
Cdd:PRK02496 2 TRLIFLGPPGAGKGtqavVLAEHLHIPH----ISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 84 TDR-LLFDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRrvcpvcgstyhlvnqpprvpercdrdgta 162
Cdd:PRK02496 78 AANgWILDGFPRKVTQAAFLDELLQEIGQSGERVVNLDVPDDVVVERLLAR----------------------------- 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 505062433 163 leQRPDDTADVIEVRQRIYNEHGLPILAHYREHapDRFRTVNGEQSYEAVYAETCRALG 221
Cdd:PRK02496 129 --GRKDDTEEVIRRRLEVYREQTAPLIDYYRDR--QKLLTIDGNQSVEAVTTELKAALA 183
|
|
| PRK14527 |
PRK14527 |
adenylate kinase; Provisional |
10-221 |
2.48e-27 |
|
adenylate kinase; Provisional
Pssm-ID: 237745 [Multi-domain] Cd Length: 191 Bit Score: 102.95 E-value: 2.48e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIF-GRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDRLL 88
Cdd:PRK14527 8 VVIFlGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVRVI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRrvcpvcgstyhlvnqpprvpercdrdgTALEQRPD 168
Cdd:PRK14527 88 FDGFPRTLAQAEALDRLLEELGARLLAVVLLEVPDEELIRRIVER---------------------------ARQEGRSD 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYRehAPDRFRTVNGEQSYEAVYAETCRALG 221
Cdd:PRK14527 141 DNEETVRRRQQVYREQTQPLVDYYE--ARGHLKRVDGLGTPDEVYARILKALG 191
|
|
| PLN02459 |
PLN02459 |
probable adenylate kinase |
9-193 |
1.24e-26 |
|
probable adenylate kinase
Pssm-ID: 215253 [Multi-domain] Cd Length: 261 Bit Score: 103.00 E-value: 1.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 9 HVVIFGRPGSGK----SSLAEQLGADHgfllIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLK---T 81
Cdd:PLN02459 31 NWVFLGCPGVGKgtyaSRLSKLLGVPH----IATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEageE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 82 PGTDRLLFDGFPRTMGQVPILAKFEQilnfrIDCYLEIAVSHEAAVKRMTGRRVCPVCGSTYHL--------------VN 147
Cdd:PLN02459 107 EGESGFILDGFPRTVRQAEILEGVTD-----IDLVVNLKLREEVLVEKCLGRRICSECGKNFNVadidlkgedgrpgiVM 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 505062433 148 QPPRVPERCDrdgTALEQRPDDTADVIEVRQRIYNEHGLPILAHYR 193
Cdd:PLN02459 182 PPLLPPPECA---SKLITRADDTEEVVKARLRVYKEESQPVEDFYR 224
|
|
| PRK14528 |
PRK14528 |
adenylate kinase; Provisional |
10-220 |
1.54e-24 |
|
adenylate kinase; Provisional
Pssm-ID: 172994 [Multi-domain] Cd Length: 186 Bit Score: 95.46 E-value: 1.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDS-LIGELLEQTLKTPGTDRLL 88
Cdd:PRK14528 4 IIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSvVIGIIKDRIREADCKNGFL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 89 FDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRRVcpvcgstyhlvnqpprvpercdrdgtaLEQRPD 168
Cdd:PRK14528 84 LDGFPRTVEQADALDALLKNEGKSIDKAINLEVPDGELLKRLLGRAE---------------------------IEGRAD 136
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 505062433 169 DTADVIEVRQRIYNEHGLPILAHYRehAPDRFRTVNGEQSYEAVYAETCRAL 220
Cdd:PRK14528 137 DNEATIKNRLDNYNKKTLPLLDFYA--AQKKLSQVNGVGSLEEVTSLIQKEL 186
|
|
| PRK14531 |
PRK14531 |
adenylate kinase; Provisional |
14-221 |
5.33e-22 |
|
adenylate kinase; Provisional
Pssm-ID: 172997 [Multi-domain] Cd Length: 183 Bit Score: 88.71 E-value: 5.33e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 14 GRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDRLLFDGFP 93
Cdd:PRK14531 9 GPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKALNSGGWLLDGFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 94 RTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRrvcpvcgstyhlvnqpprvpercdrdgtaleQRPDDTADV 173
Cdd:PRK14531 89 RTVAQAEALEPLLEELKQPIEAVVLLELDDAVLIERLLAR-------------------------------GRADDNEAV 137
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 505062433 174 IEVRQRIYNEHGLPILAHYREHApdRFRTVNGEQSYEAVYAETCRALG 221
Cdd:PRK14531 138 IRNRLEVYREKTAPLIDHYRQRG--LLQSVEAQGSIEAITERIEKVLA 183
|
|
| UMP_CMP_kin_fam |
TIGR01359 |
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ... |
10-215 |
4.12e-21 |
|
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.
Pssm-ID: 273576 [Multi-domain] Cd Length: 185 Bit Score: 86.66 E-value: 4.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAI-RKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR-L 87
Cdd:TIGR01359 2 VFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIkREGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSSKkF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 88 LFDGFPRTMGQvpiLAKFEQILNFRIDC--YLEIAVSHEAAVKRMTGRrvcpvcgstyhlvNQPprvpercdrdgtalEQ 165
Cdd:TIGR01359 82 LIDGFPRNEEN---LEAWEKLMDNKVNFkfVLFFDCPEETMIKRLLKR-------------GQT--------------SG 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 505062433 166 RPDDTADVIEVRQRIYNEHGLPILAHYRehAPDRFRTVNGEQSYEAVYAE 215
Cdd:TIGR01359 132 RVDDNIETLKKRFRTYNEETLPIIEHFE--NKGKVKEINAEGSVEEVFED 179
|
|
| PRK14529 |
PRK14529 |
adenylate kinase; Provisional |
10-221 |
4.37e-21 |
|
adenylate kinase; Provisional
Pssm-ID: 237746 [Multi-domain] Cd Length: 223 Bit Score: 87.47 E-value: 4.37e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDRLLF 89
Cdd:PRK14529 3 ILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDGKNGWLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 90 DGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRRVCPVCGstyhlvNQPPRV------PE--RCDRDGT 161
Cdd:PRK14529 83 DGFPRNKVQAEKLWEALQKEGMKLDYVIEILLPREVAKNRIMGRRLCKNDN------NHPNNIfidaikPDgdVCRVCGG 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505062433 162 ALEQRPDDT-ADVIEVRQRIY--NEHGLPILAHYREHAPDRFRT----VNGEQSYEAVYAETCRALG 221
Cdd:PRK14529 157 ELSTRADDQdEEAINKRHDIYydTETGTLAAAYFFKDLAAKGSTkyieLDGEGSIDEIKETLLKQLS 223
|
|
| PRK13808 |
PRK13808 |
adenylate kinase; Provisional |
10-221 |
9.87e-21 |
|
adenylate kinase; Provisional
Pssm-ID: 172341 [Multi-domain] Cd Length: 333 Bit Score: 88.41 E-value: 9.87e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDS----LIGELLEQTLKTPGtd 85
Cdd:PRK13808 3 LILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEvvvgIISDRIEQPDAANG-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 86 rLLFDGFPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRrvcpvcgstyhlvnqpprVPERCDRdgtALEQ 165
Cdd:PRK13808 81 -FILDGFPRTVPQAEALDALLKDKQLKLDAVVELRVNEGALLARVETR------------------VAEMRAR---GEEV 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 505062433 166 RPDDTADVIEVRQRIYNEHGLPILAHYREHApdRFRTVNGEQSYEAVYAETCRALG 221
Cdd:PRK13808 139 RADDTPEVLAKRLASYRAQTEPLVHYYSEKR--KLLTVDGMMTIDEVTREIGRVLA 192
|
|
| aden_kin_iso1 |
TIGR01360 |
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ... |
12-220 |
1.42e-18 |
|
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.
Pssm-ID: 130427 [Multi-domain] Cd Length: 188 Bit Score: 79.86 E-value: 1.42e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 12 IFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELL-EQTLKTPGTDR-LLF 89
Cdd:TIGR01360 8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLkDAMVAALGTSKgFLI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 90 DGFPRTMGQVpilAKFEQilnfRI---DCYLEIAVSHEAAVKRMTGRrvcpvcgstyhlvnqpprvpercdrdgTALEQR 166
Cdd:TIGR01360 88 DGYPREVKQG---EEFER----RIgppTLVLYFDCSEDTMVKRLLKR---------------------------AETSGR 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 505062433 167 PDDTADVIEVRQRIYNEHGLPILAHYREHApdRFRTVNGEQSYEAVYAETCRAL 220
Cdd:TIGR01360 134 VDDNEKTIKKRLETYYKATEPVIAYYETKG--KLRKINAEGTVDDVFLQVCTAI 185
|
|
| PLN02200 |
PLN02200 |
adenylate kinase family protein |
7-194 |
7.25e-14 |
|
adenylate kinase family protein
Pssm-ID: 215125 [Multi-domain] Cd Length: 234 Bit Score: 68.38 E-value: 7.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 7 PTHVVIFGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDR 86
Cdd:PLN02200 43 PFITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNK 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 87 LLFDGFPRTMGQvpiLAKFEQILNFRIDCYLEIAVSHEAAVKRMTGRRvcpvcgstyhlvnqpprvpercdrdgtalEQR 166
Cdd:PLN02200 123 FLIDGFPRTEEN---RIAFERIIGAEPNVVLFFDCPEEEMVKRVLNRN-----------------------------QGR 170
|
170 180
....*....|....*....|....*...
gi 505062433 167 PDDTADVIEVRQRIYNEHGLPILAHYRE 194
Cdd:PLN02200 171 VDDNIDTIKKRLKVFNALNLPVIDYYSK 198
|
|
| ADK_lid |
pfam05191 |
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ... |
133-168 |
2.72e-13 |
|
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.
Pssm-ID: 461578 [Multi-domain] Cd Length: 36 Bit Score: 61.71 E-value: 2.72e-13
10 20 30
....*....|....*....|....*....|....*.
gi 505062433 133 RRVCPVCGSTYHLVNQPPRVPERCDRDGTALEQRPD 168
Cdd:pfam05191 1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
|
|
| AAA_17 |
pfam13207 |
AAA domain; |
13-134 |
7.95e-12 |
|
AAA domain;
Pssm-ID: 463810 [Multi-domain] Cd Length: 136 Bit Score: 60.72 E-value: 7.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 13 FGRPGSGKSSLAEQLGADHGFLLIRTGELLRNAIRKGDpLGVRAEQLIKGGNLVPDSLIGELLEQTLKTPGTDRLLFDGF 92
Cdd:pfam13207 1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG-LVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGGVIVDGH 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 505062433 93 PRTMGQVPILAKFE----QILNFRIDCYLEiaVSHEAAVKRMTGRR 134
Cdd:pfam13207 80 PRIKTPAGYLPGLPvevlRELKPDAIILLE--ADPEEILERRLKDR 123
|
|
| COG0645 |
COG0645 |
Predicted kinase, contains AAA domain [General function prediction only]; |
10-38 |
3.63e-04 |
|
Predicted kinase, contains AAA domain [General function prediction only];
Pssm-ID: 440410 [Multi-domain] Cd Length: 164 Bit Score: 39.90 E-value: 3.63e-04
10 20
....*....|....*....|....*....
gi 505062433 10 VVIFGRPGSGKSSLAEQLGADHGFLLIRT 38
Cdd:COG0645 2 ILVCGLPGSGKSTLARALAERLGAVRLRS 30
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
10-92 |
7.42e-04 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 39.51 E-value: 7.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 10 VVIFGRPGSGKSSLAEQL---GADHGF--LLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLV------------PDSLIG 72
Cdd:COG0467 23 TLLSGPPGTGKTTLALQFlaeGLRRGEkgLYVSFEESPEQLLRRAESLGLDLEEYIESGLLRiidlspeelgldLEELLA 102
|
90 100
....*....|....*....|
gi 505062433 73 ELLEQtLKTPGTDRLLFDGF 92
Cdd:COG0467 103 RLREA-VEEFGAKRVVIDSL 121
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
12-127 |
3.23e-03 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 37.33 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 12 IFGRPGSGKSSLAEQLGAD--------------HGFLLIRTGELLRNAIRKGDPLGVRAEQLIkggnLV--PDSL----- 70
Cdd:cd01393 6 IYGPPGSGKTQLALQLAANalllgggvvwidteGAFPPSRLVQILEASPSSELELAEALSRLL----YFrpPDTLahlla 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505062433 71 IGELLEQTLKTPGTDRLLFDG--------FPRTMGQVPILAKFEQILNFRIDCYLEIAVSHEAAV 127
Cdd:cd01393 82 LDSLPESLFPPPNTSLVVVDSvsalfrkaFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAV 146
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
6-90 |
5.48e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 36.20 E-value: 5.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505062433 6 PPTHVVIFGRPGSGKSSLAEQLGA-----DHGFLLIRTGELLRNAIRKGDPLGVRAEQLIKGGNLVPDSLIGELLEQTLK 80
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARelgppGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD 80
|
90
....*....|
gi 505062433 81 TpgtdrLLFD 90
Cdd:smart00382 81 V-----LILD 85
|
|
| |
