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Conserved domains on  [gi|505065862|ref|WP_015252964|]
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MULTISPECIES: anti-sigma-W factor RsiW [Bacillus]

Protein Classification

anti-sigma factor family protein( domain architecture ID 11475862)

anti-sigma factor family protein may contain an N-terminal zinc-finger domain and belong to the zinc-associated anti-sigma factor (ZAS) family such as Bacillus subtilis anti-sigma-W factor RsiW and Mycobacterium tuberculosis anti-sigma-L factor RslA

Gene Ontology:  GO:0046872|GO:0016020
PubMed:  28319136

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RsiW COG5662
Transmembrane transcriptional regulator RsiW (anti-sigma-W factor) [Transcription];
1-201 4.41e-20

Transmembrane transcriptional regulator RsiW (anti-sigma-W factor) [Transcription];


:

Pssm-ID: 444381 [Multi-domain]  Cd Length: 155  Bit Score: 82.59  E-value: 4.41e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505065862   1 MSCpEQIVQLMHMHLDGDILPKDEHVLNEHLETCEKCRKHFYEMEKSIALVRST--SHVEAPADFTANVMAKLPKEKKRa 78
Cdd:COG5662    1 MTC-DDVEELLHAYLDGELSPEERAEVEAHLATCPACAARLAELRRLRAALRAAlaPDEPVPARLRARVMARLPRRRRR- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505065862  79 svkRWFRthpvIAAAAvfiiLMGGGFfnswhndhnfsvskqpnlvvhnhtvtvpegETVKGDVTVKNGKLIIKGKIDgdv 158
Cdd:COG5662   79 ---RWRA----VAAAD----LSAAGF------------------------------RLVGGRLLPIDGGPDAGHRIT--- 114

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 505065862 159 tvvngeKYMASAGQVTgqIEEINQLFDWTWYKMKSAGKSVLDA 201
Cdd:COG5662  115 ------LYVRPASAFR--QEGGVNVFYWRDGGLGYALVGDLDR 149
 
Name Accession Description Interval E-value
RsiW COG5662
Transmembrane transcriptional regulator RsiW (anti-sigma-W factor) [Transcription];
1-201 4.41e-20

Transmembrane transcriptional regulator RsiW (anti-sigma-W factor) [Transcription];


Pssm-ID: 444381 [Multi-domain]  Cd Length: 155  Bit Score: 82.59  E-value: 4.41e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505065862   1 MSCpEQIVQLMHMHLDGDILPKDEHVLNEHLETCEKCRKHFYEMEKSIALVRST--SHVEAPADFTANVMAKLPKEKKRa 78
Cdd:COG5662    1 MTC-DDVEELLHAYLDGELSPEERAEVEAHLATCPACAARLAELRRLRAALRAAlaPDEPVPARLRARVMARLPRRRRR- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505065862  79 svkRWFRthpvIAAAAvfiiLMGGGFfnswhndhnfsvskqpnlvvhnhtvtvpegETVKGDVTVKNGKLIIKGKIDgdv 158
Cdd:COG5662   79 ---RWRA----VAAAD----LSAAGF------------------------------RLVGGRLLPIDGGPDAGHRIT--- 114

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 505065862 159 tvvngeKYMASAGQVTgqIEEINQLFDWTWYKMKSAGKSVLDA 201
Cdd:COG5662  115 ------LYVRPASAFR--QEGGVNVFYWRDGGLGYALVGDLDR 149
zf-HC2 pfam13490
Putative zinc-finger; This is a putative zinc-finger found in some anti-sigma factor proteins.
 3-38 6.04e-06

Putative zinc-finger; This is a putative zinc-finger found in some anti-sigma factor proteins.


Pssm-ID: 463895 [Multi-domain]  Cd Length: 35  Bit Score: 41.76  E-value: 6.04e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 505065862    3 CpEQIVQLMHMHLDGDILPKDEHVLNEHLETCEKCR 38
Cdd:pfam13490   1 C-EEVRELLSAYLDGELSPEERARVEAHLAGCPACR 35
anti_SigH_actin TIGR02949
anti-sigma factor, TIGR02949 family; This group of anti-sigma factors are associated in an ...
 2-71 6.17e-05

anti-sigma factor, TIGR02949 family; This group of anti-sigma factors are associated in an apparent operon with a family of sigma-70 family sigma factors (TIGR02947). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family. This family is restricted to the Actinobacteria. [Transcription, Transcription factors]


Pssm-ID: 188261  Cd Length: 84  Bit Score: 40.13  E-value: 6.17e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505065862    2 SCPEQIVQLmHMHLDGDILPKDEHVLNEHLETCEKCRKHfYEMEKSI--ALVRSTSHVEAPADFTANVMAKL 71
Cdd:TIGR02949   8 DCAEVIDHL-YEFLDGECTEDDAERLRRHLAACPECLRE-YDLEQAVrkLLKRCCRTEAAPEELRARLLGRI 77
 
Name Accession Description Interval E-value
RsiW COG5662
Transmembrane transcriptional regulator RsiW (anti-sigma-W factor) [Transcription];
1-201 4.41e-20

Transmembrane transcriptional regulator RsiW (anti-sigma-W factor) [Transcription];


Pssm-ID: 444381 [Multi-domain]  Cd Length: 155  Bit Score: 82.59  E-value: 4.41e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505065862   1 MSCpEQIVQLMHMHLDGDILPKDEHVLNEHLETCEKCRKHFYEMEKSIALVRST--SHVEAPADFTANVMAKLPKEKKRa 78
Cdd:COG5662    1 MTC-DDVEELLHAYLDGELSPEERAEVEAHLATCPACAARLAELRRLRAALRAAlaPDEPVPARLRARVMARLPRRRRR- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505065862  79 svkRWFRthpvIAAAAvfiiLMGGGFfnswhndhnfsvskqpnlvvhnhtvtvpegETVKGDVTVKNGKLIIKGKIDgdv 158
Cdd:COG5662   79 ---RWRA----VAAAD----LSAAGF------------------------------RLVGGRLLPIDGGPDAGHRIT--- 114

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 505065862 159 tvvngeKYMASAGQVTgqIEEINQLFDWTWYKMKSAGKSVLDA 201
Cdd:COG5662  115 ------LYVRPASAFR--QEGGVNVFYWRDGGLGYALVGDLDR 149
YlaD COG5660
Anti-sigma-YlaC factor YlaD, contains Zn-finger domain [Signal transduction mechanisms];
1-104 5.14e-11

Anti-sigma-YlaC factor YlaD, contains Zn-finger domain [Signal transduction mechanisms];


Pssm-ID: 444379 [Multi-domain]  Cd Length: 219  Bit Score: 59.79  E-value: 5.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505065862   1 MSCpEQIVQLMHMHLDGDILPKDEHVLNEHLETCEKCRKHFYEMEKSIALVRSTSHVEAPaDFTANVMAKLPKEKKRAsv 80
Cdd:COG5660    1 MDC-ETCREALSARLDGELEPVPAAEVDAHLAGCPACRAWLERAAALTRRLRTRPAPEVP-DLTDAILAAAPPAFPRR-- 76

                         90       100
                 ....*....|....*....|....*...
gi 505065862  81 KRWFRTHPVIAAAAVFII----LMGGGF 104
Cdd:COG5660   77 RAYLRLALALVALAQLALglaqLLGSDV 104
zf-HC2 pfam13490
Putative zinc-finger; This is a putative zinc-finger found in some anti-sigma factor proteins.
 3-38 6.04e-06

Putative zinc-finger; This is a putative zinc-finger found in some anti-sigma factor proteins.


Pssm-ID: 463895 [Multi-domain]  Cd Length: 35  Bit Score: 41.76  E-value: 6.04e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 505065862    3 CpEQIVQLMHMHLDGDILPKDEHVLNEHLETCEKCR 38
Cdd:pfam13490   1 C-EEVRELLSAYLDGELSPEERARVEAHLAGCPACR 35
anti_SigH_actin TIGR02949
anti-sigma factor, TIGR02949 family; This group of anti-sigma factors are associated in an ...
 2-71 6.17e-05

anti-sigma factor, TIGR02949 family; This group of anti-sigma factors are associated in an apparent operon with a family of sigma-70 family sigma factors (TIGR02947). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family. This family is restricted to the Actinobacteria. [Transcription, Transcription factors]


Pssm-ID: 188261  Cd Length: 84  Bit Score: 40.13  E-value: 6.17e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505065862    2 SCPEQIVQLmHMHLDGDILPKDEHVLNEHLETCEKCRKHfYEMEKSI--ALVRSTSHVEAPADFTANVMAKL 71
Cdd:TIGR02949   8 DCAEVIDHL-YEFLDGECTEDDAERLRRHLAACPECLRE-YDLEQAVrkLLKRCCRTEAAPEELRARLLGRI 77
Bactofilin pfam04519
Polymer-forming cytoskeletal; This is a family of bactofilins, a functionally diverse class of ...
 123-177 1.27e-04

Polymer-forming cytoskeletal; This is a family of bactofilins, a functionally diverse class of cytoskeletal, polymer-forming, proteins that is widely conserved among bacteria. In the example species C. crescentus, two bactofilins assemble into a membrane-associated laminar structure that shows cell-cycle-dependent polar localization and acts as a platform for the recruitment of a cell wall biosynthetic enzyme involved in polar morphogenesis. Bactofilins display distinct subcellular distributions and dynamics in different bacterial species, suggesting that they are versatile structural elements that have adopted a range of different cellular functions.


Pssm-ID: 461340 [Multi-domain]  Cd Length: 89  Bit Score: 39.32  E-value: 1.27e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 505065862  123 VVHNHTVTVPEGETVKGDVTVKNgkLIIKGKIDGDVTvVNGEKYMASAGQVTGQI 177
Cdd:pfam04519  21 ITSKGTLVIGEGGRVEGDIKAES--VVIAGTVEGNIT-ASEKLELLSTARVEGDI 72
antisig_RsrA TIGR03988
mycothiol system anti-sigma-R factor; Members of this family are the anti-sigma-R factor RsrA, ...
 2-71 9.52e-04

mycothiol system anti-sigma-R factor; Members of this family are the anti-sigma-R factor RsrA, which contains a CXXC motif as a thiol-disulphide redox switch. It interacts with sigma-R. It regulates and is regulated by the mycothiol system, which occurs in many actinomycetes. [Transcription, Transcription factors]


Pssm-ID: 274904  Cd Length: 77  Bit Score: 36.90  E-value: 9.52e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505065862    2 SCPEqIVQLMHMHLDGDILPKDEHVLNEHLETCEKCRKHfYEMEKSI-ALV-RSTSHVEAPADFTANVMAKL 71
Cdd:TIGR03988   1 DCSE-VLAEVYEYLDGELDDEDCARLRAHLDECPPCLEQ-YGLEEEVkSLVaRCCGGESAPEELRARILARI 70
CcmA COG1664
Cytoskeletal protein CcmA, bactofilin family [Cytoskeleton];
118-178 1.18e-03

Cytoskeletal protein CcmA, bactofilin family [Cytoskeleton];


Pssm-ID: 441270 [Multi-domain]  Cd Length: 129  Bit Score: 37.57  E-value: 1.18e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505065862 118 KQPNLVVHNHTVTVPEGETVKGDVTVKnGKLIIKGKIDGDVTvVNGEKYMASAGQVTGQIE 178
Cdd:COG1664    4 KKSAAESEGITTVIGEGTTIKGDITSE-GDLRIDGTVEGDIT-AEGTLVIGEGGVVEGDIE 62
CcmA COG1664
Cytoskeletal protein CcmA, bactofilin family [Cytoskeleton];
126-178 4.28e-03

Cytoskeletal protein CcmA, bactofilin family [Cytoskeleton];


Pssm-ID: 441270 [Multi-domain]  Cd Length: 129  Bit Score: 36.03  E-value: 4.28e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 505065862 126 NHTVTVPEGETVKGDVTVKNgkLIIKGKIDGDVTVvnGEK-YMASAGQVTGQIE 178
Cdd:COG1664   46 EGTLVIGEGGVVEGDIEADN--VVINGTVEGNITA--SEKlELLSTARVEGDIT 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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