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Conserved domains on  [gi|505178578|ref|WP_015365680|]
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microcin C ABC transporter permease [Klebsiella aerogenes]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15021 super family cl33063
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


The actual alignment was detected with superfamily member PRK15021:

Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 634.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578   1 MSFLSPVNQARWARFRHNRRGYWSLWIFLALFICSLCAELIANDKPLLVQYRGSLYVPALKTYSETTFGGDFATAADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  81 PWLQKRLTENGWVLWAPVRFGATSINFATDSPFPSPPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVL 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 161 AGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 241 LGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGMAAFLSVAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|.
gi 505178578 321 LTLLIFIGEAVRDAFDPGKAV 341
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKAV 341
 
Name Accession Description Interval E-value
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 634.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578   1 MSFLSPVNQARWARFRHNRRGYWSLWIFLALFICSLCAELIANDKPLLVQYRGSLYVPALKTYSETTFGGDFATAADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  81 PWLQKRLTENGWVLWAPVRFGATSINFATDSPFPSPPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVL 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 161 AGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 241 LGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGMAAFLSVAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|.
gi 505178578 321 LTLLIFIGEAVRDAFDPGKAV 341
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKAV 341
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 600.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578   1 MSFLSPVNQARWARFRHNRRGYWSLWIFLALFICSLCAELIANDKPLLVQYRGSLYVPALKTYSETTFGGDFATAADYQD 80
Cdd:COG4239    1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  81 PWLQKRLTENGWVLWAPVRFGATSINFATDSPFPSPPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVL 160
Cdd:COG4239   81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 161 AGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:COG4239  161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 241 LGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGMAAFLSVAVL 320
Cdd:COG4239  241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                        330       340
                 ....*....|....*....|
gi 505178578 321 LTLLIFIGEAVRDAFDPGKA 340
Cdd:COG4239  321 LSLLVFIGEAVRDAFDPRKT 340
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-338 4.49e-22

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 91.59  E-value: 4.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  158 GVLAGALQG-YYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPD----FWWLLAITVLFGWMTLVGVVRAEFLRTRNY 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  233 DYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGfglplGSPSLGELLLQGKNNLQAPWlGMA 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*.
gi 505178578  313 AFLSVAVLLTLLIFIGEAVRDAFDPG 338
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 154-324 1.33e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 79.63  E-value: 1.33e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 154 SSVLGVLAGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSV--------VQPDFWWLLAITVLFGWMTLVGVVRAE 225
Cdd:cd06261   15 ALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLfgvllgwgILPGLGLPALILALLLIAPFARLIRRA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 226 FLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGspsLGELLLQGKNNLQ 305
Cdd:cd06261   95 ALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG---PGTGLLLIFAILF 171

                        170
                 ....*....|....*....
gi 505178578 306 APWLGMAAFLSVAVLLTLL 324
Cdd:cd06261  172 PGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 634.71  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578   1 MSFLSPVNQARWARFRHNRRGYWSLWIFLALFICSLCAELIANDKPLLVQYRGSLYVPALKTYSETTFGGDFATAADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  81 PWLQKRLTENGWVLWAPVRFGATSINFATDSPFPSPPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVL 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 161 AGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 241 LGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGMAAFLSVAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|.
gi 505178578 321 LTLLIFIGEAVRDAFDPGKAV 341
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKAV 341
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 600.60  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578   1 MSFLSPVNQARWARFRHNRRGYWSLWIFLALFICSLCAELIANDKPLLVQYRGSLYVPALKTYSETTFGGDFATAADYQD 80
Cdd:COG4239    1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  81 PWLQKRLTENGWVLWAPVRFGATSINFATDSPFPSPPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVL 160
Cdd:COG4239   81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 161 AGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:COG4239  161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 241 LGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGMAAFLSVAVL 320
Cdd:COG4239  241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                        330       340
                 ....*....|....*....|
gi 505178578 321 LTLLIFIGEAVRDAFDPGKA 340
Cdd:COG4239  321 LSLLVFIGEAVRDAFDPRKT 340
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 116-336 9.78e-60

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 193.02  E-value: 9.78e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 116 PPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVLAGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILL 195
Cdd:COG1173   54 PPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIAL 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 196 SSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSITT 275
Cdd:COG1173  134 VAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILA 213

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505178578 276 LTSLDFLGFGLPLGSPSLGELLLQGKNNLQ-APWLGMAAFLSVAVLLTLLIFIGEAVRDAFD 336
Cdd:COG1173  214 EAGLSFLGLGVQPPTPSWGTMLSEGRNYLLtAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 92-337 7.50e-32

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 121.10  E-value: 7.50e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  92 WVLWAPV--RFGATSINFATDSPFPSPPSRHnWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVLAGALQGYYG 169
Cdd:PRK15406  52 FVILAPMlsQFAYDDTDWGMMSSAPDMESGH-YFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLG 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 170 GKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRHII 249
Cdd:PRK15406 131 GKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIV 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 250 LRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQ-APWLGMAAFLSVAVLLTLLIFIG 328
Cdd:PRK15406 211 LRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEvSPWLLLFPAGFLVVTLFCFNFIG 290


                 ....*....
gi 505178578 329 EAVRDAFDP 337
Cdd:PRK15406 291 DGLRDALDP 299
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 115-337 6.75e-27

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 107.51  E-value: 6.75e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 115 SPPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVLAGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIIL 194
Cdd:PRK15082  74 AGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIA 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 195 LSSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSIT 274
Cdd:PRK15082 154 VVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSII 233

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505178578 275 TLTSLDFLGFGLPLGSPSLGELLLQGKNNL-QAPwlGMAAFLSVAVLLTLLIF--IGEAVRDAFDP 337
Cdd:PRK15082 234 TAASLSFLGLGAQPPTPEWGAMLNEARADMvIAP--HVALFPSLAIFLTVLAFnlLGDGLRDALDP 297
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
116-337 2.96e-25

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 102.97  E-value: 2.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 116 PPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVLAGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILL 195
Cdd:PRK09881  69 PPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMAL 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 196 SSVVQPDFW-WLLAITVLfGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSIT 274
Cdd:PRK09881 149 AAALGPSLFnAMLAIAIV-RIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAIL 227

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505178578 275 TLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLgMAAFLSVAVLLTLLIF--IGEAVRDAFDP 337
Cdd:PRK09881 228 MAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWW-YCAFPGAAILLTAVGFnlFGDGIRDLLDP 291
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-338 4.49e-22

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 91.59  E-value: 4.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  158 GVLAGALQG-YYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPD----FWWLLAITVLFGWMTLVGVVRAEFLRTRNY 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578  233 DYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGfglplGSPSLGELLLQGKNNLQAPWlGMA 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*.
gi 505178578  313 AFLSVAVLLTLLIFIGEAVRDAFDPG 338
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDPR 180
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
123-337 4.37e-20

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 88.69  E-value: 4.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 123 LGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVLAGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPD 202
Cdd:PRK10913  81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 203 FW-WLLAITVLfGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDF 281
Cdd:PRK10913 161 IVnAALALTFV-ALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGF 239

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505178578 282 LGFGLPLGSPSLGELLLQGKNNLQAPWLgMAAFLSVAVLLTLLIF--IGEAVRDAFDP 337
Cdd:PRK10913 240 LGMGAQPPTPEWGTMLSDVLQFAQSAWW-VVTFPGLAILLTVLAFnlMGDGLRDALDP 296
nikC PRK10417
nickel transporter permease NikC; Provisional
 116-337 1.40e-19

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 87.03  E-value: 1.40e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 116 PPSRHNWLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVLAGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILL 195
Cdd:PRK10417  42 SPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFM 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 196 SSVVQPDFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSITT 275
Cdd:PRK10417 122 VGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLH 201

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505178578 276 LTSLDFLGFGLPLGSPSLGELLLQGKN-----NLQAPWLGMAAFLSVAVLLTLlifiGEAVRDAFDP 337
Cdd:PRK10417 202 VAGLSFLGLGVTAPTAEWGVMINDARQyiwtqPLLMFWPGLALFISVMAFNLL----GDALRDHLDP 264
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 154-324 1.33e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 79.63  E-value: 1.33e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 154 SSVLGVLAGALQGYYGGKLDLWGQRFIEVWSGMPTLFLIILLSSV--------VQPDFWWLLAITVLFGWMTLVGVVRAE 225
Cdd:cd06261   15 ALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLfgvllgwgILPGLGLPALILALLLIAPFARLIRRA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 226 FLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGspsLGELLLQGKNNLQ 305
Cdd:cd06261   95 ALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG---PGTGLLLIFAILF 171

                        170
                 ....*....|....*....
gi 505178578 306 APWLGMAAFLSVAVLLTLL 324
Cdd:cd06261  172 PGDLGVAAAVALILLLLSL 190
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 156-337 1.59e-09

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 58.16  E-value: 1.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 156 VLGVLAGALQGYYGGKldlWGQRFIEVWS----GMPTLFLIILLSSV---------------VQPDFW------WLLAIT 210
Cdd:COG0601  111 LIGIPLGILAALRRGS---WLDRLITVLAllgiSIPSFWLGLLLILLfavklgwlpvsgrvsPWEDFLdalrhlILPALT 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 211 VLFGWMTLVG-VVRAEFLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATLTF----LPFILCSSITTLTSldflgFG 285
Cdd:COG0601  188 LALGSLAGIArLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVlglqLGGLLGGAVVVETV-----FS 262

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 505178578 286 LPlGspsLGELLLQGKNNLQAPwLGMAAFLSVAVLLTLLIFIGEAVRDAFDP 337
Cdd:COG0601  263 WP-G---LGRLLVDAILNRDYP-VVQGIVLLIAVLVVLVNLLVDLLYALLDP 309
PRK15111 PRK15111
peptide ABC transporter permease SapC;
100-338 4.76e-07

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 50.47  E-value: 4.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 100 FGATSINFATDSPF------PSPPSRHN----WLGTDANGGDVFARILYGARISLLFGLLLTFFSSVLGVLAGALQGYYG 169
Cdd:PRK15111  45 FGGWLAPYGIDQQFlgyqllPPSWSRYGevsfFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATH 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 170 GKLDLWGQRFIEVWSGMPTLFLIILLSSVVQPDfwwlLAITVLFGWMTLVG-VVRAEFLRTR---NYDYIRAAQALGVSD 245
Cdd:PRK15111 125 GLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPS----LSHAMFAVWLALLPrMVRSIYSAVHdelEKEYVIAARLDGAST 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 246 RHIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLlqgKNNLQ----APWLGM--AAFLSVAV 319
Cdd:PRK15111 201 LNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPEWGAML---GDSLEliyvAPWTVMlpGAAIMLSV 277

                        250
                 ....*....|....*....
gi 505178578 320 LLTLLifIGEAVRDAFDPG 338
Cdd:PRK15111 278 LLVNL--LGDGIRRAIIAG 294
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 169-283 5.65e-03

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 38.19  E-value: 5.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178578 169 GGKLDLWGQRFIEVWSGMPT-LFLIIL--------------LSSVVQPDF----W--------WLLAI----TVLFGWMT 217
Cdd:PRK15133 163 GSRFDVWSSAFIIIGYAIPAfLFAILLivffaggsyfdlfpLRGLVSANFdslpWyqkitdylWHITLpvlaTVIGGFAA 242

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505178578 218 LVGVVRAEFLRTRNYDYIRAAQALGVSDRHIILRHMLPNAMVATL-----TFLPFILCSS--ITTLTSLDFLG 283
Cdd:PRK15133 243 LTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIagfpaTFISMFFTGSllIEVMFSLNGLG 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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