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Conserved domains on  [gi|505178697|ref|WP_015365799|]
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MULTISPECIES: polysaccharide biosynthesis tyrosine autokinase [Enterobacteriaceae]

Protein Classification

P-loop NTPase family protein( domain architecture ID 1562424)

P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
P-loop_NTPase super family cl38936
P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain ...
 4-703 0e+00

P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a hydrophobic residue). The Walker A and B motifs bind the beta-gamma phosphate moiety of the bound nucleotide (typically ATP or GTP) and the Mg2+ cation, respectively. The P-loop NTPases are involved in diverse cellular functions, and they can be divided into two major structural classes: the KG (kinase-GTPase) class which includes Ras-like GTPases and its circularly permutated YlqF-like; and the ASCE (additional strand catalytic E) class which includes ATPase Binding Cassette (ABC), DExD/H-like helicases, 4Fe-4S iron sulfur cluster binding proteins of NifH family, RecA-like F1-ATPases, and ATPases Associated with a wide variety of Activities (AAA). Also included are a diverse set of nucleotide/nucleoside kinase families.


The actual alignment was detected with superfamily member PRK11519:

Pssm-ID: 476819 [Multi-domain]  Cd Length: 719  Bit Score: 990.42  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   4 VRNKTA-VTDSDEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVLPDSQ 82
Cdd:PRK11519   5 VKQHAApVTGSDEIDIGRLVGTVIEARWWVIGITAVFALCAVVYTFFATPIYSADALVQIEQNSGNSLVQDIGSALANKP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  83 PQSAPEIALLRSRMILGKTVDDLNLQAKIEENHFPIFGRGLARLLGNKANNIAISRLYLSIPGEDVPeVEVQVLDKNKFS 162
Cdd:PRK11519  85 PASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADQV-FTLNVLDDKNYQ 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 163 VT-GEGIELTGTVGQLLEAKGISLLVSEIDAEPGTTFTVSYISRLKAITNLQDNLTIADEGKDTGILTLSLTGDDQTQIK 241
Cdd:PRK11519 164 LSsDGGFSARGQVGQMLKKDGVTLMVEAIHARPGTEFTVTKYSTLGMINNLQNNLTVTENGKDTGVLSLTYTGEDREQIR 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 242 NIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLEAKAVLDQIVNVDNQLNEL 321
Cdd:PRK11519 244 DILNSITRNYLEQNIERKSEEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNEL 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 322 TIRESEVSQLFTKEHPTYKALMEKRKTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIAKSSA 401
Cdd:PRK11519 324 TFKEAEISKLYTKEHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEAST 403

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 402 IGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEELGINVYASVPVSeEFAKRVERS 481
Cdd:PRK11519 404 VGDVRIVDPAITQPGVLKPKKALIILGAIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLS-EWQKARDSV 482

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 482 SKWKNKNRDEAAVFLAIENPADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFID 561
Cdd:PRK11519 483 KTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLID 562

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 562 ADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMD 641
Cdd:PRK11519 563 CDMRKGYTHELLGTNNVNGLSDILIGQGDITTAAKPTSIANFDLIPRGQVPPNPSELLMSERFAELVNWASKNYDLVLID 642

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505178697 642 TPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSGVNIKGCILNGVVKKASN 703
Cdd:PRK11519 643 TPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASA 704
 
Name Accession Description Interval E-value
PRK11519 PRK11519
tyrosine-protein kinase Wzc;
4-703 0e+00

tyrosine-protein kinase Wzc;


Pssm-ID: 183173 [Multi-domain]  Cd Length: 719  Bit Score: 990.42  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   4 VRNKTA-VTDSDEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVLPDSQ 82
Cdd:PRK11519   5 VKQHAApVTGSDEIDIGRLVGTVIEARWWVIGITAVFALCAVVYTFFATPIYSADALVQIEQNSGNSLVQDIGSALANKP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  83 PQSAPEIALLRSRMILGKTVDDLNLQAKIEENHFPIFGRGLARLLGNKANNIAISRLYLSIPGEDVPeVEVQVLDKNKFS 162
Cdd:PRK11519  85 PASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADQV-FTLNVLDDKNYQ 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 163 VT-GEGIELTGTVGQLLEAKGISLLVSEIDAEPGTTFTVSYISRLKAITNLQDNLTIADEGKDTGILTLSLTGDDQTQIK 241
Cdd:PRK11519 164 LSsDGGFSARGQVGQMLKKDGVTLMVEAIHARPGTEFTVTKYSTLGMINNLQNNLTVTENGKDTGVLSLTYTGEDREQIR 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 242 NIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLEAKAVLDQIVNVDNQLNEL 321
Cdd:PRK11519 244 DILNSITRNYLEQNIERKSEEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNEL 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 322 TIRESEVSQLFTKEHPTYKALMEKRKTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIAKSSA 401
Cdd:PRK11519 324 TFKEAEISKLYTKEHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEAST 403

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 402 IGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEELGINVYASVPVSeEFAKRVERS 481
Cdd:PRK11519 404 VGDVRIVDPAITQPGVLKPKKALIILGAIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLS-EWQKARDSV 482

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 482 SKWKNKNRDEAAVFLAIENPADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFID 561
Cdd:PRK11519 483 KTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLID 562

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 562 ADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMD 641
Cdd:PRK11519 563 CDMRKGYTHELLGTNNVNGLSDILIGQGDITTAAKPTSIANFDLIPRGQVPPNPSELLMSERFAELVNWASKNYDLVLID 642

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505178697 642 TPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSGVNIKGCILNGVVKKASN 703
Cdd:PRK11519 643 TPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASA 704
eps_transp_fam TIGR01005
exopolysaccharide transport protein family; The model describes the exopolysaccharide ...
 15-695 1.01e-115

exopolysaccharide transport protein family; The model describes the exopolysaccharide transport protein family in bacteria. The transport protein is part of a large genetic locus which is associated with exopolysaccharide (EPS) biosynthesis. Detailed molecular characterization and gene fusion analysis revealed atleast seven gene products are involved in the overall regulation, which among other things, include exopolysaccharide biosynthesis, property of conferring virulence and exopolysaccharide export. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273391 [Multi-domain]  Cd Length: 764  Bit Score: 365.97  E-value: 1.01e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   15 EIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKqgnalLNSLSQVLPDS------QPQSAPE 88
Cdd:TIGR01005   3 EIDLDRLLAALFANARLIAAFAAAFIALGAAYAFFARPVYEADIMILLDDN-----LNKAAEEEGDPsnlfdlDTDAAAA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   89 IALLRSRMILGKTVDDLNL--QAKI-EENHFPIF--------------GRGLARLLGNKANNIAISRLYLSIPGE-DVPE 150
Cdd:TIGR01005  78 IEILKSGELAGKAVDKLHLseNAKIlNPPRFPVDligawiksaaglfsEPGGFDLGEEAAGNERIDKAAADIPEAlAGEP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  151 VEVQVLDKNKFSVTGEGIELT--GTVGQLLEAK----GISLLVSEIDAEPGTTFTVSYISRLKAITNLQDNLTIADEGKD 224
Cdd:TIGR01005 158 FKLISLGAGAFRLEDKLLAAPiaGGVAEALEADqliaNFEAQENALTAKAEALFDLEQDSQAAALEMAHDKAEIAEKAAQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  225 TGILTL-SLTGDDQTQIKNIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLE 303
Cdd:TIGR01005 238 GEIIGEaQLADLNPALIAAIADQAAAEARADNIKRIADEAEENAVFLAGILPKEGDELEIADLKTNELRNGKGEFDLSDE 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  304 AKAVLDQIVNVDNQLNELTIRESEVSQLFTKEHPTYKALMEKR-KTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRA 382
Cdd:TIGR01005 318 FGADHPEAVCSAPSLQELKAKIAEELQQFTASHKGEQAIAQQIeESLRGKINGIAGKLKDAPEIEQDLRELEQDAAADKE 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  383 VYMQLLNRQQELSIAKSSAIGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEE-LG 461
Cdd:TIGR01005 398 LYESLLGDMEQAKLQKAFKIAKARLIDEAAVPEEPSKPKKLMTLALAAVLGMMLGGAAAAFLEALEGGFRDEGDIEEhLG 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  462 INVYASVPVSE-------EFAKRVERSSKWKNKNRDEAAVF-----LAIENPADLAIESIRGLRTSLHFAMMEARNNVLM 529
Cdd:TIGR01005 478 HRSLATVPLLDtqmdkkaQLTHAHFGSVKRHDEAVDDTMPFqllarIVPDAPRSTFAEAFRNAKLACDFALADAENNLIA 557

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  530 ITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRG 609
Cdd:TIGR01005 558 IAGALPDEGKSFIAANFAALIAAGGKRTLLIDADIRKGGLHQMFGKAPKPGLLDLLAGEASIEAGIHRDQRPGLAFIAAG 637

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  610 ---MVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSG 686
Cdd:TIGR01005 638 gasHFPHNPNELLANPAMAELIDNARNAFDLVLVDLAALAAVADAAAFAALADGILFVTEFERSPLGEIRDLIHQEPHAN 717


                  ....*....
gi 505178697  687 VNIKGCILN 695
Cdd:TIGR01005 718 SDVLGVIFN 726
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1-703 3.84e-83

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 277.67  E-value: 3.84e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   1 MSSvRNKTAVTDSDEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVlPD 80
Cdd:COG3206    1 MNE-SSSAPPEEEDEIDLRDLLRILRRRKWLILLVFLLVLALALLYALLLPPVYEASATLLVEPQSSDVLLSGLSSL-SA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  81 SQPQSAPEIALLRSRMILGKTVDDLNLQAKIEEnhfpifgrglarllgnkanniaisrlylsipgedvpevevqvldknk 160
Cdd:COG3206   79 SDSPLETQIEILKSRPVLERVVDKLNLDEDPLG----------------------------------------------- 111

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 161 fsvtgegieltgtvgqlleakgisllvseidaepgttftvSYISRLKAITNLQDNLTIADEgKDTGILTLSLTGDDQTQI 240
Cdd:COG3206  112 ----------------------------------------EEASREAAIERLRKNLTVEPV-KGSNVIEISYTSPDPELA 150

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 241 KNIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLEAKAVLDQIVNVDNQLNE 320
Cdd:COG3206  151 AAVANALAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAE 230

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 321 LTI--------------------------------------------RESEVSQLFTKEHPTYKALMEKR---------- 346
Cdd:COG3206  231 ARAelaeaearlaalraqlgsgpdalpellqspviqqlraqlaeleaELAELSARYTPNHPDVIALRAQIaalraqlqqe 310

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 347 -------------------KTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIAKSSAIGNVRI 407
Cdd:COG3206  311 aqrilasleaelealqareASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRV 390

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 408 IDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEELGINVYASVPVSEEFAKRVERsskwknk 487
Cdd:COG3206  391 IDPAVVPLKPVSPKKLLILALGLLLGLLLGLGLALLLELLDRTIEEELELLLLLGLPLLGPLPPLKSKRERRR------- 463

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 488 nRDEAAVFLAIENPADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKG 567
Cdd:COG3206  464 -ARLALLLLAAALAALLALLLALLLLLLLLLLLLLVSSSSGGGSSSTSSALAAASAAAAAAAALLLLLLLLLLLDLLLLL 542

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 568 YTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILA 647
Cdd:COG3206  543 LLLLLLLLLLLGGLLLLLLLLLLLLLLLLLLLLLLLLLLPPPLLLPLLLLLLLLLLLLLLLLLLLLSDDLILDLVPLLAA 622

                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505178697 648 VTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSGVNIKGCILNGVVKKASN 703
Cdd:COG3206  623 LLAAAVLAVLVVVLLLVVALVALARLALLAAALLLLLVLVVVGGVVLGGVVYGYYY 678
BY-kinase cd05387
bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on ...
 507-696 2.11e-70

bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.


Pssm-ID: 349772 [Multi-domain]  Cd Length: 190  Bit Score: 227.84  E-value: 2.11e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 507 ESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILS 586
Cdd:cd05387    1 EAFRTLRTNLLFAGSDAGPKVIAVTSASPGEGKSTVAANLAVALAQSGKRVLLIDADLRRPSLHRLLGLPNEPGLSEVLS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 587 GKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNYAGTTLLVAR 666
Cdd:cd05387   81 GQASLEDVIQSTNIPNLDVLPAGTVPPNPSELLSSPRFAELLEELKEQYDYVIIDTPPVLAVADALILAPLVDGVLLVVR 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 505178697 667 FEQNTAKEIAVSIKRFEQSGVNIKGCILNG 696
Cdd:cd05387  161 AGKTRRREVKEALERLEQAGAKVLGVVLNK 190
GNVR pfam13807
G-rich domain on putative tyrosine kinase; This domain is found between two families, Wzz, ...
 365-445 7.60e-35

G-rich domain on putative tyrosine kinase; This domain is found between two families, Wzz, pfam02706 and CbiA pfam01656. There is a highly conserved GNVR sequence motif which characterizes this domain. The function is not known.


Pssm-ID: 433492 [Multi-domain]  Cd Length: 82  Bit Score: 126.94  E-value: 7.60e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  365 ETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIAKSSAIGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLAR 444
Cdd:pfam13807   1 DTQQEILRLTRDVEVNTEIYTQLLNSNQELEVVKAGTVGNVRIVDTAVVPPKPVKPKKALIVVLALLLGLMLGVGLVLLR 80


                  .
gi 505178697  445 V 445
Cdd:pfam13807  81 R 81
 
Name Accession Description Interval E-value
PRK11519 PRK11519
tyrosine-protein kinase Wzc;
4-703 0e+00

tyrosine-protein kinase Wzc;


Pssm-ID: 183173 [Multi-domain]  Cd Length: 719  Bit Score: 990.42  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   4 VRNKTA-VTDSDEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVLPDSQ 82
Cdd:PRK11519   5 VKQHAApVTGSDEIDIGRLVGTVIEARWWVIGITAVFALCAVVYTFFATPIYSADALVQIEQNSGNSLVQDIGSALANKP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  83 PQSAPEIALLRSRMILGKTVDDLNLQAKIEENHFPIFGRGLARLLGNKANNIAISRLYLSIPGEDVPeVEVQVLDKNKFS 162
Cdd:PRK11519  85 PASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADQV-FTLNVLDDKNYQ 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 163 VT-GEGIELTGTVGQLLEAKGISLLVSEIDAEPGTTFTVSYISRLKAITNLQDNLTIADEGKDTGILTLSLTGDDQTQIK 241
Cdd:PRK11519 164 LSsDGGFSARGQVGQMLKKDGVTLMVEAIHARPGTEFTVTKYSTLGMINNLQNNLTVTENGKDTGVLSLTYTGEDREQIR 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 242 NIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLEAKAVLDQIVNVDNQLNEL 321
Cdd:PRK11519 244 DILNSITRNYLEQNIERKSEEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNEL 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 322 TIRESEVSQLFTKEHPTYKALMEKRKTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIAKSSA 401
Cdd:PRK11519 324 TFKEAEISKLYTKEHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITEAST 403

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 402 IGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEELGINVYASVPVSeEFAKRVERS 481
Cdd:PRK11519 404 VGDVRIVDPAITQPGVLKPKKALIILGAIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLS-EWQKARDSV 482

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 482 SKWKNKNRDEAAVFLAIENPADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFID 561
Cdd:PRK11519 483 KTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLID 562

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 562 ADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMD 641
Cdd:PRK11519 563 CDMRKGYTHELLGTNNVNGLSDILIGQGDITTAAKPTSIANFDLIPRGQVPPNPSELLMSERFAELVNWASKNYDLVLID 642

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505178697 642 TPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSGVNIKGCILNGVVKKASN 703
Cdd:PRK11519 643 TPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASA 704
PRK09841 PRK09841
tyrosine-protein kinase;
1-702 0e+00

tyrosine-protein kinase;


Pssm-ID: 182106 [Multi-domain]  Cd Length: 726  Bit Score: 956.67  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   1 MSSVRNKT--AVTDSDEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVL 78
Cdd:PRK09841   1 MTTKNMNTppGSTQENEIDLLRLVGELWDHRKFIISVTALFTLIAVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  79 PDSQPQSAPEIALLRSRMILGKTVDDLNLQAKIEENHFPIFGRGLARLLGNKANNIAISRLYL-SIPGEDVPEVeVQVLD 157
Cdd:PRK09841  81 PNSSPESAPEIQLLQSRMILGKTIAELNLRDIVEQKYFPIVGRGWARLTKEKPGELAISWMHIpQLNGQDQQLT-LTVGE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 158 KNKFSVTGEGIELTGTVGQLLEAKGISLLVSEIDAEPGTTFTVSYISRLKAITNLQDNLTIADEGKDTGILTLSLTGDDQ 237
Cdd:PRK09841 160 NGHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETFTVSERSKESGMLELTMTGDDP 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 238 TQIKNIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLEAKAVLDQIVNVDNQ 317
Cdd:PRK09841 240 QLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQLPEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQ 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 318 LNELTIRESEVSQLFTKEHPTYKALMEKRKTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIA 397
Cdd:PRK09841 320 LNELTFREAEISQLYKKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNRQQELSIS 399

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 398 KSSAIGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEELGINVYASVPVSEEFAKR 477
Cdd:PRK09841 400 KSSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLRRGVEAPEQLEEHGISVYATIPMSEWLDKR 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 478 VER------SSKWKNKNRDeaAVFLAIENPADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIA 551
Cdd:PRK09841 480 TRLrkknlfSNQQRHRTKN--IPFLAVDNPADSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIA 557

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 552 QTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWA 631
Cdd:PRK09841 558 QSDQKVLFIDADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSELLMRDRMRQLLEWA 637

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505178697 632 NEHYDLVVMDTPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSGVNIKGCILNGVVKKAS 702
Cdd:PRK09841 638 NDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVSLSMQRLEQAGVNIKGAILNGVIKRAS 708
eps_transp_fam TIGR01005
exopolysaccharide transport protein family; The model describes the exopolysaccharide ...
 15-695 1.01e-115

exopolysaccharide transport protein family; The model describes the exopolysaccharide transport protein family in bacteria. The transport protein is part of a large genetic locus which is associated with exopolysaccharide (EPS) biosynthesis. Detailed molecular characterization and gene fusion analysis revealed atleast seven gene products are involved in the overall regulation, which among other things, include exopolysaccharide biosynthesis, property of conferring virulence and exopolysaccharide export. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273391 [Multi-domain]  Cd Length: 764  Bit Score: 365.97  E-value: 1.01e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   15 EIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKqgnalLNSLSQVLPDS------QPQSAPE 88
Cdd:TIGR01005   3 EIDLDRLLAALFANARLIAAFAAAFIALGAAYAFFARPVYEADIMILLDDN-----LNKAAEEEGDPsnlfdlDTDAAAA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   89 IALLRSRMILGKTVDDLNL--QAKI-EENHFPIF--------------GRGLARLLGNKANNIAISRLYLSIPGE-DVPE 150
Cdd:TIGR01005  78 IEILKSGELAGKAVDKLHLseNAKIlNPPRFPVDligawiksaaglfsEPGGFDLGEEAAGNERIDKAAADIPEAlAGEP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  151 VEVQVLDKNKFSVTGEGIELT--GTVGQLLEAK----GISLLVSEIDAEPGTTFTVSYISRLKAITNLQDNLTIADEGKD 224
Cdd:TIGR01005 158 FKLISLGAGAFRLEDKLLAAPiaGGVAEALEADqliaNFEAQENALTAKAEALFDLEQDSQAAALEMAHDKAEIAEKAAQ 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  225 TGILTL-SLTGDDQTQIKNIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLE 303
Cdd:TIGR01005 238 GEIIGEaQLADLNPALIAAIADQAAAEARADNIKRIADEAEENAVFLAGILPKEGDELEIADLKTNELRNGKGEFDLSDE 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  304 AKAVLDQIVNVDNQLNELTIRESEVSQLFTKEHPTYKALMEKR-KTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRA 382
Cdd:TIGR01005 318 FGADHPEAVCSAPSLQELKAKIAEELQQFTASHKGEQAIAQQIeESLRGKINGIAGKLKDAPEIEQDLRELEQDAAADKE 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  383 VYMQLLNRQQELSIAKSSAIGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEE-LG 461
Cdd:TIGR01005 398 LYESLLGDMEQAKLQKAFKIAKARLIDEAAVPEEPSKPKKLMTLALAAVLGMMLGGAAAAFLEALEGGFRDEGDIEEhLG 477

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  462 INVYASVPVSE-------EFAKRVERSSKWKNKNRDEAAVF-----LAIENPADLAIESIRGLRTSLHFAMMEARNNVLM 529
Cdd:TIGR01005 478 HRSLATVPLLDtqmdkkaQLTHAHFGSVKRHDEAVDDTMPFqllarIVPDAPRSTFAEAFRNAKLACDFALADAENNLIA 557

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  530 ITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRG 609
Cdd:TIGR01005 558 IAGALPDEGKSFIAANFAALIAAGGKRTLLIDADIRKGGLHQMFGKAPKPGLLDLLAGEASIEAGIHRDQRPGLAFIAAG 637

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  610 ---MVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSG 686
Cdd:TIGR01005 638 gasHFPHNPNELLANPAMAELIDNARNAFDLVLVDLAALAAVADAAAFAALADGILFVTEFERSPLGEIRDLIHQEPHAN 717


                  ....*....
gi 505178697  687 VNIKGCILN 695
Cdd:TIGR01005 718 SDVLGVIFN 726
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1-703 3.84e-83

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 277.67  E-value: 3.84e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   1 MSSvRNKTAVTDSDEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVlPD 80
Cdd:COG3206    1 MNE-SSSAPPEEEDEIDLRDLLRILRRRKWLILLVFLLVLALALLYALLLPPVYEASATLLVEPQSSDVLLSGLSSL-SA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  81 SQPQSAPEIALLRSRMILGKTVDDLNLQAKIEEnhfpifgrglarllgnkanniaisrlylsipgedvpevevqvldknk 160
Cdd:COG3206   79 SDSPLETQIEILKSRPVLERVVDKLNLDEDPLG----------------------------------------------- 111

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 161 fsvtgegieltgtvgqlleakgisllvseidaepgttftvSYISRLKAITNLQDNLTIADEgKDTGILTLSLTGDDQTQI 240
Cdd:COG3206  112 ----------------------------------------EEASREAAIERLRKNLTVEPV-KGSNVIEISYTSPDPELA 150

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 241 KNIIDSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSLEAKAVLDQIVNVDNQLNE 320
Cdd:COG3206  151 AAVANALAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAE 230

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 321 LTI--------------------------------------------RESEVSQLFTKEHPTYKALMEKR---------- 346
Cdd:COG3206  231 ARAelaeaearlaalraqlgsgpdalpellqspviqqlraqlaeleaELAELSARYTPNHPDVIALRAQIaalraqlqqe 310

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 347 -------------------KTLQEEKNKLNKRVSAMPETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIAKSSAIGNVRI 407
Cdd:COG3206  311 aqrilasleaelealqareASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRV 390

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 408 IDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEELGINVYASVPVSEEFAKRVERsskwknk 487
Cdd:COG3206  391 IDPAVVPLKPVSPKKLLILALGLLLGLLLGLGLALLLELLDRTIEEELELLLLLGLPLLGPLPPLKSKRERRR------- 463

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 488 nRDEAAVFLAIENPADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKG 567
Cdd:COG3206  464 -ARLALLLLAAALAALLALLLALLLLLLLLLLLLLVSSSSGGGSSSTSSALAAASAAAAAAAALLLLLLLLLLLDLLLLL 542

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 568 YTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILA 647
Cdd:COG3206  543 LLLLLLLLLLLGGLLLLLLLLLLLLLLLLLLLLLLLLLLPPPLLLPLLLLLLLLLLLLLLLLLLLLSDDLILDLVPLLAA 622

                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505178697 648 VTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSGVNIKGCILNGVVKKASN 703
Cdd:COG3206  623 LLAAAVLAVLVVVLLLVVALVALARLALLAAALLLLLVLVVVGGVVLGGVVYGYYY 678
BY-kinase cd05387
bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on ...
 507-696 2.11e-70

bacterial tyrosine-kinase; Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.


Pssm-ID: 349772 [Multi-domain]  Cd Length: 190  Bit Score: 227.84  E-value: 2.11e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 507 ESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILS 586
Cdd:cd05387    1 EAFRTLRTNLLFAGSDAGPKVIAVTSASPGEGKSTVAANLAVALAQSGKRVLLIDADLRRPSLHRLLGLPNEPGLSEVLS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 587 GKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNYAGTTLLVAR 666
Cdd:cd05387   81 GQASLEDVIQSTNIPNLDVLPAGTVPPNPSELLSSPRFAELLEELKEQYDYVIIDTPPVLAVADALILAPLVDGVLLVVR 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 505178697 667 FEQNTAKEIAVSIKRFEQSGVNIKGCILNG 696
Cdd:cd05387  161 AGKTRRREVKEALERLEQAGAKVLGVVLNK 190
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 527-702 1.73e-58

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 199.64  E-value: 1.73e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 527 VLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDYI 606
Cdd:COG0489   94 VIAVTSGKGGEGKSTVAANLALALAQSGKRVLLIDADLRGPSLHRMLGLENRPGLSDVLAGEASLEDVIQPTEVEGLDVL 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 607 SRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIAVSIKRFEQSG 686
Cdd:COG0489  174 PAGPLPPNPSELLASKRLKQLLEELRGRYDYVIIDTPPGLGVADATLLASLVDGVLLVVRPGKTALDDVRKALEMLEKAG 253

                        170
                 ....*....|....*.
gi 505178697 687 VNIKGCILNGVVKKAS 702
Cdd:COG0489  254 VPVLGVVLNMVCPKGE 269
eps_fam TIGR01007
capsular exopolysaccharide family; This model describes the capsular exopolysaccharide ...
 507-697 1.87e-45

capsular exopolysaccharide family; This model describes the capsular exopolysaccharide proteins in bacteria. The exopolysaccharide gene cluster consists of several genes which encode a number of proteins which regulate the exoploysaccharide biosynthesis(EPS). Atleast 13 genes espA to espM in streptococcus species seem to direct the EPS proteins and all of which share high homology. Functional roles were characterized by gene disruption experiments which resulted in exopolysaccharide-deficient phenotypes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273392 [Multi-domain]  Cd Length: 204  Bit Score: 161.07  E-value: 1.87e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  507 ESIRGLRTSLHFAMmeARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTEN-NNGLSDIL 585
Cdd:TIGR01007   1 EYYNAIRTNIQFSG--AEIKVLLITSVKPGEGKSTTSANIAIAFAQAGYKTLLIDGDMRNSVMSGTFKSQNkITGLTNFL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  586 SGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNYAGTTLLVA 665
Cdd:TIGR01007  79 SGTTDLSDAICDTNIENLDVITAGPVPPNPTELLQSSNFKTLIETLRKRFDYIIIDTPPIGTVTDAAIIARACDASILVT 158

                         170       180       190
                  ....*....|....*....|....*....|..
gi 505178697  666 RFEQNTAKEIAVSIKRFEQSGVNIKGCILNGV 697
Cdd:TIGR01007 159 DAGKIKKREVKKAKEQLEQAGSNFLGVVLNKV 190
GNVR pfam13807
G-rich domain on putative tyrosine kinase; This domain is found between two families, Wzz, ...
 365-445 7.60e-35

G-rich domain on putative tyrosine kinase; This domain is found between two families, Wzz, pfam02706 and CbiA pfam01656. There is a highly conserved GNVR sequence motif which characterizes this domain. The function is not known.


Pssm-ID: 433492 [Multi-domain]  Cd Length: 82  Bit Score: 126.94  E-value: 7.60e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  365 ETQQEVLRLSRDVDSGRAVYMQLLNRQQELSIAKSSAIGNVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLAR 444
Cdd:pfam13807   1 DTQQEILRLTRDVEVNTEIYTQLLNSNQELEVVKAGTVGNVRIVDTAVVPPKPVKPKKALIVVLALLLGLMLGVGLVLLR 80


                  .
gi 505178697  445 V 445
Cdd:pfam13807  81 R 81
EpsG TIGR03029
chain length determinant protein tyrosine kinase EpsG; The proteins in this family are ...
 501-695 1.91e-34

chain length determinant protein tyrosine kinase EpsG; The proteins in this family are homologs of the EpsG protein found in Methylobacillus strain 12S and are generally found in operons with other Eps homologs. The protein is believed to function as the protein tyrosine kinase component of the chain length regulator (along with the transmembrane component EpsF).


Pssm-ID: 132074 [Multi-domain]  Cd Length: 274  Bit Score: 132.68  E-value: 1.91e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  501 PADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNG 580
Cdd:TIGR03029  79 PFSPQVEALRALRSQLMLRWFSEGRKALAVVSAKSGEGCSYIAANLAIVFSQLGEKTLLIDANLRDPVQHRNFKLSEQRG 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  581 LSDILSGKSSIEKAVQKISKIGFDYISRGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNYAGT 660
Cdd:TIGR03029 159 LSDILAGRSDLEVITHIPALENLSVLPAGAIPPNPQELLARPAFTDLLNKVMGDYDVVIVDTPSAEHSSDAQIVATRARG 238

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 505178697  661 TLLVARFEQNTAKEIAVSIKRFEQSGVNIKGCILN 695
Cdd:TIGR03029 239 TLIVSRVNETRLHELTSLKEHLSGVGVRVVGAVLN 273
Wzz pfam02706
Chain length determinant protein; This family includes proteins involved in lipopolysaccharide ...
 14-104 1.38e-26

Chain length determinant protein; This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases.


Pssm-ID: 460658 [Multi-domain]  Cd Length: 90  Bit Score: 103.91  E-value: 1.38e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697   14 DEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVLPDSQPQSApEIALLR 93
Cdd:pfam02706   1 DEIDLIELLGVLWKRKKLIILVTLLFTLLAAAYAFLATPKYTATAQILVPQKKGEAGSLLGSDLQAGLQLAST-EIEILK 79

                          90
                  ....*....|.
gi 505178697   94 SRMILGKTVDD 104
Cdd:pfam02706  80 SRDVLEKVIDE 90
WzzB COG3765
LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope ...
 12-449 3.08e-14

LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442979 [Multi-domain]  Cd Length: 364  Bit Score: 75.01  E-value: 3.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  12 DSDEIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVLpdsqpqsapeIAL 91
Cdd:COG3765   18 QDDEIDLFELLRTLWQGKLWIIGITLLFALLALVYAFLLPQKWTSTAIVDPPTVNELGGYYSQRQFL----------RNL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  92 LRSRMILGKTVDDLnlqakieenhFPIFGRglarllgnKANNIAISRLYLSipGEDVPEVEVQVLDKNKfsvtgegielt 171
Cdd:COG3765   88 DVKSVDPPVISSEL----------FNEFIK--------QLSSYDLRREFLL--QSDYYKQLQEGDEKED----------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 172 gtvgqlleAKGISLLVSEIDAEPgttftvsyisrlkaitnlqdnltiADEGKDT---GILTLSLTGDDQTQIKNI----I 244
Cdd:COG3765  137 --------AALLDELINNISITP------------------------PDDKKKSspyTNYSVSFTAETPEDAQQLlrgyI 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 245 DSISTNYLAQNIARQAAQDAKSLEFLSEQLPKVRSDLDLA-EDKLNGYRQqkdsvDLSLEAKAVLDQIVNVDNQLNeltI 323
Cdd:COG3765  185 DFANQRVLKELNEELQGAIAARLQSLKAQIKRLEEVAKAQrQRRIERLKY-----ALKIAQAAGIKKPVYSNGQTP---A 256

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 324 RESEVSQLFTKehpTYKALMEKRKTLQEeknklnkrvsampetQQEVLRLSRDVDSGRAVYMQLlnrqQELSIAKSSAIG 403
Cdd:COG3765  257 VKLDPSYLFLL---GTDALQAELEILKA---------------RGDDYPLNADLYQLQAQLAQL----NALPIDDVGFQP 314

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*.
gi 505178697 404 nVRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRK 449
Cdd:COG3765  315 -FRYLRTPEEPVKKDKPKRALILVLGALLGGMLGVGVVLIRHALRS 359
YveK COG3944
Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];
338-566 2.29e-13

Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443144 [Multi-domain]  Cd Length: 309  Bit Score: 71.64  E-value: 2.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 338 TYKALMEKRKTLQEEKNKLN---------KRVSAMPETQQEVLRLS-RDVDSGRAVymQLLNRQQELSIAKSSAI---GN 404
Cdd:COG3944   72 TYAELLKSPAVLEEVIDELGldlspeelaKKISVTSPPDTQVITITvTDTDPERAA--DIANAVAEVFAEEVKELmkvDN 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 405 VRIIDNAITQPKPVKPNKVLVILLGIVIGLLISVGLVLARVVLRKGIESPEQLEELgINVYASVPVSEefakrversskw 484
Cdd:COG3944  150 VTVLDPATVPASPVSPNPKLNLAIGLVLGLLLGVGLAFLRELLDTTIRSEEDIERL-LGLLLGGAVPA------------ 216

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 485 knkNRDEAAVFLAIENPADLAIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDADL 564
Cdd:COG3944  217 ---ARSARPLLLLLADASPRAAAARRRRRNLLFALAAVDARTVVVVSSSLSEGKSTTTAALALALAAAAAGVVLVLADLD 293


                 ..
gi 505178697 565 RK 566
Cdd:COG3944  294 RR 295
CpaE COG4963
Flp pilus assembly ATPase CpaE/TadZ, contains N-terminal REC/TadZ_N domain [Intracellular ...
 427-665 3.18e-12

Flp pilus assembly ATPase CpaE/TadZ, contains N-terminal REC/TadZ_N domain [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443989 [Multi-domain]  Cd Length: 358  Bit Score: 68.60  E-value: 3.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 427 LLGIVIGLLISVGLVLARVVLRKGIESPEQLEELGINVYASVPVSEEFAKRVERSSKWKNKNRDEAAVFLA--IENPADL 504
Cdd:COG4963    2 LVALRPLPRISIQAFCESAALAALIEAAAEDRRLALAAVAVASGGAAAAAAAYLSAPTPNLILLEALSESAalLADVLPL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 505 AIESIRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVIAQ-TGKKVLFIDADLRKGYTHKLFNTENNNGLSD 583
Cdd:COG4963   82 SPDELRAALARLLDPGAARRGRVIAVVGAKGGVGATTLAVNLAWALAReSGRRVLLVDLDLQFGDVALYLDLEPRRGLAD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 584 ILSGKSS-----IEKAVQKISKiGFDYISrGMVPPNPAELLMHKRFGELIAWANEHYDLVVMDTPPILAVTDAAVIGNyA 658
Cdd:COG4963  162 ALRNPDRldetlLDRALTRHSS-GLSVLA-APADLERAEEVSPEAVERLLDLLRRHFDYVVVDLPRGLNPWTLAALEA-A 238


                 ....*..
gi 505178697 659 GTTLLVA 665
Cdd:COG4963  239 DEVVLVT 245
FlhG-like cd02038
MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) ...
 538-644 3.77e-12

MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) is a major determinant for a variety of flagellation patterns. It effects location and number of bacterial flagella during C-ring assembly.


Pssm-ID: 349758 [Multi-domain]  Cd Length: 230  Bit Score: 66.44  E-value: 3.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 538 GKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKiGFDYIS-----RGMVP 612
Cdd:cd02038   13 GKTNVSANLALALSKLGKRVLLLDADLGLANLDILLGLAPKKTLGDVLKGRVSLEDIIVEGPE-GLDIIPggsgmEELAN 91

                         90       100       110
                 ....*....|....*....|....*....|..
gi 505178697 613 PNPAellMHKRFGELIAWANEHYDLVVMDTPP 644
Cdd:cd02038   92 LDPE---QKAKLIEELSSLESNYDYLLIDTGA 120
FlhG COG0455
MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell ...
 541-644 4.72e-10

MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440223 [Multi-domain]  Cd Length: 230  Bit Score: 60.29  E-value: 4.72e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 541 FISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNNGLSDILSGKSSIEKAVQKISKiGFDYISRGMVPPNPAELLM 620
Cdd:COG0455    1 TVAVNLAAALARLGKRVLLVDADLGLANLDVLLGLEPKATLADVLAGEADLEDAIVQGPG-GLDVLPGGSGPAELAELDP 79

                         90       100
                 ....*....|....*....|....
gi 505178697 621 HKRFGELIAWANEHYDLVVMDTPP 644
Cdd:COG0455   80 EERLIRVLEELERFYDVVLVDTGA 103
ParA COG1192
ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein ...
 538-654 1.91e-09

ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440805 [Multi-domain]  Cd Length: 253  Bit Score: 58.72  E-value: 1.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 538 GKTFISSNLAEVIAQTGKKVLFIDAD----LRKGYthKLFNTENNNGLSDILSGKSSIEKAVQKISKIGFDyisrgMVPP 613
Cdd:COG1192   14 GKTTTAVNLAAALARRGKRVLLIDLDpqgnLTSGL--GLDPDDLDPTLYDLLLDDAPLEDAIVPTEIPGLD-----LIPA 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 505178697 614 NP----AELLM------HKRFGELIAWANEHYDLVVMDTPPILAV-TDAAVI 654
Cdd:COG1192   87 NIdlagAEIELvsrpgrELRLKRALAPLADDYDYILIDCPPSLGLlTLNALA 138
YveK COG3944
Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];
15-113 2.64e-08

Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443144 [Multi-domain]  Cd Length: 309  Bit Score: 56.23  E-value: 2.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  15 EIDLGRLVGELIDHRKLIISVTSLFTLLALVYALFATPIYQADALVQVEQKQGNALLNSLSQVLPDSQP-QSAPEIAllR 93
Cdd:COG3944    1 EMDLREYLRILRRRWWLILLLTLLGALAALASSFLITPVYQASTTLLVSTSSGSDASDLYQGIQTAQQLvNTYAELL--K 78

                         90       100
                 ....*....|....*....|
gi 505178697  94 SRMILGKTVDDLNLQAKIEE 113
Cdd:COG3944   79 SPAVLEEVIDELGLDLSPEE 98
CbiA pfam01656
CobQ/CobB/MinD/ParA nucleotide binding domain; This family consists of various cobyrinic acid ...
 528-649 3.25e-08

CobQ/CobB/MinD/ParA nucleotide binding domain; This family consists of various cobyrinic acid a,c-diamide synthases. These include CbiA and CbiP from S.typhimurium, and CobQ from R. capsulatus. These amidases catalyze amidations to various side chains of hydrogenobyrinic acid or cobyrinic acid a,c-diamide in the biosynthesis of cobalamin (vitamin B12) from uroporphyrinogen III. Vitamin B12 is an important cofactor and an essential nutrient for many plants and animals and is primarily produced by bacteria. The family also contains dethiobiotin synthetases as well as the plasmid partitioning proteins of the MinD/ParA family.


Pssm-ID: 426369 [Multi-domain]  Cd Length: 228  Bit Score: 54.66  E-value: 3.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  528 LMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDAD---------LRKGYTHKLFNTennngLSDILSGKSSIEKAVQKI 598
Cdd:pfam01656   1 IAIAGTKGGVGKTTLAANLARALARRGLRVLLIDLDpqsnnssveGLEGDIAPALQA-----LAEGLKGRVNLDPILLKE 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 505178697  599 --SKIGFDYISRGMVPPNPAELLMHKRFGELIAWA----NEHYDLVVMDTPPILAVT 649
Cdd:pfam01656  76 ksDEGGLDLIPGNIDLEKFEKELLGPRKEERLREAlealKEDYDYVIIDGAPGLGEL 132
AAA_31 pfam13614
AAA domain; This family includes a wide variety of AAA domains including some that have lost ...
 538-646 1.13e-07

AAA domain; This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.


Pssm-ID: 433350 [Multi-domain]  Cd Length: 177  Bit Score: 52.20  E-value: 1.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  538 GKTFISSNLAEVIAQTGKKVLFIDAD----LRKGYTHKLFNTENNngLSDILSGKSSIEKAVQKISKIGFDYIsrgmvPP 613
Cdd:pfam13614  14 GKTTTSVNLAAALAKKGKKVLLIDLDpqgnATSGLGIDKNNVEKT--IYELLIGECNIEEAIIKTVIENLDLI-----PS 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 505178697  614 N----PAELLM------HKRFGELIAWANEHYDLVVMDTPPIL 646
Cdd:pfam13614  87 NidlaGAEIELigienrENILKEALEPVKDNYDYIIIDCPPSL 129
minD_arch TIGR01969
cell division ATPase MinD, archaeal; This model represents the archaeal branch of the MinD ...
 538-697 1.54e-06

cell division ATPase MinD, archaeal; This model represents the archaeal branch of the MinD family. MinD, a weak ATPase, works in bacteria with MinC as a generalized cell division inhibitor and, through interaction with MinE, prevents septum placement inappropriate sites. Often several members of this family are found in archaeal genomes, and the function is uncharacterized. More distantly related proteins ParA chromosome partitioning proteins. The exact roles of the various archaeal MinD homologs are unknown.


Pssm-ID: 131024 [Multi-domain]  Cd Length: 251  Bit Score: 50.11  E-value: 1.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  538 GKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENNN-GLSDILSGKSSIEKAVqkiskigfdYISRGMVPPNPA 616
Cdd:TIGR01969  13 GKTTITANLGVALAKLGKKVLALDADITMANLELILGMEDKPvTLHDVLAGEADIKDAI---------YEGPFGVKVIPA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  617 ELLMHK-------RFGELIAWANEHYDLVVMDTPPILAVTdaAVIGNYAGTTLLVARFEQNTAKEIAVSIKRF-EQSGVN 688
Cdd:TIGR01969  84 GVSLEGlrkadpdKLEDVLKEIIDDTDFLLIDAPAGLERD--AVTALAAADELLLVVNPEISSITDALKTKIVaEKLGTA 161


                  ....*....
gi 505178697  689 IKGCILNGV 697
Cdd:TIGR01969 162 ILGVVLNRV 170
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
257-373 2.67e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 2.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697  257 ARQAAQDAKSLEFLSEQLPKVRSDLDLAEDKLNGYRQQKDSVDLSL--EAKAVLDQIVNVDNQLNELTIRESEVSQLFTK 334
Cdd:COG4913   330 AQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLpaSAEEFAALRAEAAALLEALEEELEALEEALAE 409

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 505178697  335 EHPTYKALMEKRKTLQEEKNKLNKRVSAMPETQQEVLRL 373
Cdd:COG4913   410 AEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448
Mrp_NBP35 cd02037
Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically ...
 538-644 1.25e-03

Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically iron-sulfur (FeS) cluster scaffolds that function to assemble nascent FeS clusters for transfer to FeS-requiring enzymes. Members include the eukaryotic nucleotide-binding protein 1 (NUBP1) which is a component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery and the archael [NiFe] hydrogenase maturation protein HypB which is required for nickel insertion into [NiFe] hydrogenase.


Pssm-ID: 349757 [Multi-domain]  Cd Length: 213  Bit Score: 40.95  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505178697 538 GKTFISSNLAEVIAQTGKKVLFIDADLRKGYTHKLFNTENnnglSDILSGKSSIE----KAVQKISkIGFdyisrgMVPP 613
Cdd:cd02037   13 GKSTVAVNLALALAKKGYKVGLLDADIYGPSIPRLLGVEG----KPLHQSEEGIVpvevGGIKVMS-IGF------LLPE 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 505178697 614 NPA-------------ELLMHKRFGELiawanehyDLVVMDTPP 644
Cdd:cd02037   82 DDAviwrgpmksgaikQFLKDVDWGEL--------DYLIIDLPP 117
ParAB_family cd02042
partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved ...
 537-563 1.28e-03

partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.


Pssm-ID: 349760 [Multi-domain]  Cd Length: 130  Bit Score: 39.45  E-value: 1.28e-03
                         10        20
                 ....*....|....*....|....*..
gi 505178697 537 AGKTFISSNLAEVIAQTGKKVLFIDAD 563
Cdd:cd02042   12 VGKTTLAVNLAAALALRGKRVLLIDLD 38
SIMIBI cd01983
SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal ...
 526-563 4.23e-03

SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal recognition particle, MinD, and BioD), consists of signal recognition particle (SRP) GTPases, the assemblage of MinD-like ATPases, which are involved in protein localization, chromosome partitioning, and membrane transport, and a group of metabolic enzymes with kinase or related phosphate transferase activity. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.


Pssm-ID: 349751 [Multi-domain]  Cd Length: 107  Bit Score: 37.41  E-value: 4.23e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 505178697 526 NVLMITGASPNAGKTFISSNLAEVIAQTGKKVLFIDAD 563
Cdd:cd01983    1 RVIAVTGGKGGVGKTTLAAALAVALAAKGYKVLLIDLD 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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