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Conserved domains on  [gi|505180171|ref|WP_015367273|]
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ABC transporter ATP-binding protein [Klebsiella aerogenes]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-340 4.39e-126

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 365.19  E-value: 4.39e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIG 80
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMrgvPKAEIRARVAELLELVGLEG-LADRYPHQLSGGQQQRVALARALAPEPRVLLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDA 237
Cdd:COG3842  160 DEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 238 LVLDAELME---GRARCAIGELPTDDPH---ANGRGRVMLRPEQLRVSSCAPQES-AFRIVDVDFAGHISTLTV-SAAGQ 309
Cdd:COG3842  240 NLLPGTVLGdegGGVRTGGRTLEVPADAglaAGGPVTVAIRPEDIRLSPEGPENGlPGTVEDVVFLGSHVRYRVrLGDGQ 319

                        330       340       350
                 ....*....|....*....|....*....|..
gi 505180171 310 SMPLVLKTVSQAAWQAGAAVRLDV-IGQARIF 340
Cdd:COG3842  320 ELVVRVPNRAALPLEPGDRVGLSWdPEDVVVL 351
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-340 4.39e-126

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 365.19  E-value: 4.39e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIG 80
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMrgvPKAEIRARVAELLELVGLEG-LADRYPHQLSGGQQQRVALARALAPEPRVLLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDA 237
Cdd:COG3842  160 DEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 238 LVLDAELME---GRARCAIGELPTDDPH---ANGRGRVMLRPEQLRVSSCAPQES-AFRIVDVDFAGHISTLTV-SAAGQ 309
Cdd:COG3842  240 NLLPGTVLGdegGGVRTGGRTLEVPADAglaAGGPVTVAIRPEDIRLSPEGPENGlPGTVEDVVFLGSHVRYRVrLGDGQ 319

                        330       340       350
                 ....*....|....*....|....*....|..
gi 505180171 310 SMPLVLKTVSQAAWQAGAAVRLDV-IGQARIF 340
Cdd:COG3842  320 ELVVRVPNRAALPLEPGDRVGLSWdPEDVVVL 351
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 2-216 4.93e-98

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 288.65  E-value: 4.93e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIGF 81
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG----VPPERRNIGM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03259   77 VFQDYALFPHLTVAENIAFGLKlrgVPKAEIRARVRELLELVGLEG-LLNRYPHELSGGQQQRVALARALAREPSLLLLD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03259  156 EPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-278 2.52e-88

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 269.89  E-value: 2.52e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIGF 81
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI----THVPAENRHVNT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK09452  91 VFQSYALFPHMTVFENVAFGLRMqktPAAEITPRVMEALRMVQLEE-FAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:PRK09452 170 ESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEIN 249

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 505180171 239 VLDAE----LMEGRARCAIGELP----TDDPHANGRG-RVMLRPEQLRV 278
Cdd:PRK09452 250 IFDATvierLDEQRVRANVEGREcniyVNFAVEPGQKlHVLLRPEDLRV 298
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 2-310 5.96e-82

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 253.04  E-value: 5.96e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIGF 81
Cdd:TIGR03265   5 LSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDI----TRLPPQKRDYGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   82 VPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR03265  81 VFQSYALFPNLTVADNIAYGLKnrgMGRAEVAERVAELLDLVGLP-GSERKYPGQLSGGQQQRVALARALATSPGLLLLD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:TIGR03265 160 EPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVN 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171  239 VLDAELMEG-RARCAIGELPTDD--PHANGRGRVMLRPEQLRVSSCAPQESAF--RIVDVDFAGHISTLTVSAAGQS 310
Cdd:TIGR03265 240 WLPGTRGGGsRARVGGLTLACAPglAQPGASVRLAVRPEDIRVSPAGNAANLLlaRVEDMEFLGAFYRLRLRLEGLP 316
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 17-162 1.50e-48

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 160.12  E-value: 1.50e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfVPAHQRGIGFVPQEGALFPHLNVAD 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE--RKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171   97 NIAWGLDC---SREEKRRRVAALMEMVALDATLASHW---PHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:pfam00005  79 NLRLGLLLkglSKREKDARAEEALEKLGLGDLADRPVgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
1-212 6.88e-40

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 139.85  E-value: 6.88e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA----DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL----FAEGVFV 72
Cdd:NF038007   1 MLNMQNAEKCYItktiKTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVtnlsYSQKIIL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  73 paHQRGIGFVPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALA 149
Cdd:NF038007  81 --RRELIGYIFQSFNLIPHLSIFDNVALPLkyrGVAKKERIERVNQVLNLFGIDNR-RNHKPMQLSGGQQQRVAIARAMV 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 150 QRPSLMLLDEPFSALDtglraaTRKATADL-----LAEAGVASILVTHDQtEALSFASQVAVMRQGRF 212
Cdd:NF038007 158 SNPALLLADEPTGNLD------SKNARAVLqqlkyINQKGTTIIMVTHSD-EASTYGNRIINMKDGKL 218
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
10-199 4.50e-31

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 115.79  E-value: 4.50e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  10 SFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaegvfvpahqRGIGFVPQEGAL- 88
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG-------------ARVAYVPQRSEVp 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  89 --FPhLNVADNIAWG-------LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:NF040873  68 dsLP-LTVRDLVAMGrwarrglWRRLTRDDRAAVDDALERVGL-ADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDE 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 505180171 160 PFSALDtglrAATRKATADLLAEA---GVASILVTHDQTEALS 199
Cdd:NF040873 146 PTTGLD----AESRERIIALLAEEharGATVVVVTHDLELVRR 184
GguA NF040905
sugar ABC transporter ATP-binding protein;
1-211 1.29e-27

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 112.58  E-value: 1.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAG------FEtpdnGRIVLQGNTL-F-----AE 68
Cdd:NF040905   1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGEVCrFkdirdSE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  69 gvfvpahQRGIGFVPQEGALFPHLNVADNIAWGLDCSR------EEKRRRVAALMEMVALD---ATLASHwpheISGGQQ 139
Cdd:NF040905  77 -------ALGIVIIHQELALIPYLSIAENIFLGNERAKrgvidwNETNRRARELLAKVGLDespDTLVTD----IGVGKQ 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 140 QRVALARALAQRPSLMLLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:NF040905 146 QLVEIAKALSKDVKLLILDEPTAALN----EEDSAALLDLLLElkaQGITSIIISHKLNEIRRVADSITVLRDGR 216
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-160 3.38e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 67.46  E-value: 3.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI-VLQGNtlFAEgvfvPAHQRG--- 78
Cdd:NF033858   3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVeVLGGD--MAD----ARHRRAvcp 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 -IGFVPQ--EGALFPHLNVADNIA-----WGLDcsREEKRRRVAALMEMVALDATL---ASHwpheISGGQQQRVALARA 147
Cdd:NF033858  77 rIAYMPQglGKNLYPTLSVFENLDffgrlFGQD--AAERRRRIDELLRATGLAPFAdrpAGK----LSGGMKQKLGLCCA 150

                        170
                 ....*....|...
gi 505180171 148 LAQRPSLMLLDEP 160
Cdd:NF033858 151 LIHDPDLLILDEP 163
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 26-199 6.87e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 62.39  E-value: 6.87e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    26 PGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqgntlfaegvfvpahqrgigfvpqegalfphlnvadniawgLDCS 105
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----------------------------------------IDGE 39

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   106 REEKRRRVAALMEMVALDatlashwPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA-----ATRKATADLL 180
Cdd:smart00382  40 DILEEVLDQLLLIIVGGK-------KASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEAlllllEELRLLLLLK 112

                          170
                   ....*....|....*....
gi 505180171   181 AEAGVASILVTHDQTEALS 199
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGP 131
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-224 4.78e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 63.22  E-value: 4.78e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLlRILAGFETPDNGRIVLQGNTLFAEGvfvPAHQRGIGF 81
Cdd:NF000106  14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TWCANR---RALRRTIG* 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 -VPQEGALFPHLNVADN---IAWGLDCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:NF000106  90 hRPVR*GRRESFSGRENlymIGR*LDLSRKDARARADELLERFSLTEA-AGRAAAKYSGGMRRRLDLAASMIGRPAVLYL 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:NF000106 169 DEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTK 234
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
8-165 5.51e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 41.65  E-value: 5.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   8 SKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVfvpAHQRGIGFVPQEGA 87
Cdd:NF033858 273 TMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDI---ATRRRVGYMSQAFS 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  88 LFPHLNVADNI---AWGLDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:NF033858 350 LYGELTVRQNLelhARLFHLPAAEIAARVAEMLERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGV 428


                 .
gi 505180171 165 D 165
Cdd:NF033858 429 D 429
GguA NF040905
sugar ABC transporter ATP-binding protein;
135-230 3.01e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 39.39  E-value: 3.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 135 SGGQQQRVALARALAQRPSLMLLDEPFSALDTGlraatrkatA--------DLLAEAGVASILVTHDQTEALSFASQVAV 206
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVG---------AkyeiytiiNELAAEGKGVIVISSELPELLGMCDRIYV 476

                         90       100
                 ....*....|....*....|....
gi 505180171 207 MRQGRFaqVGtpfEVysrPVDEAT 230
Cdd:NF040905 477 MNEGRI--TG---EL---PREEAS 492
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-340 4.39e-126

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 365.19  E-value: 4.39e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIG 80
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMrgvPKAEIRARVAELLELVGLEG-LADRYPHQLSGGQQQRVALARALAPEPRVLLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDA 237
Cdd:COG3842  160 DEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 238 LVLDAELME---GRARCAIGELPTDDPH---ANGRGRVMLRPEQLRVSSCAPQES-AFRIVDVDFAGHISTLTV-SAAGQ 309
Cdd:COG3842  240 NLLPGTVLGdegGGVRTGGRTLEVPADAglaAGGPVTVAIRPEDIRLSPEGPENGlPGTVEDVVFLGSHVRYRVrLGDGQ 319

                        330       340       350
                 ....*....|....*....|....*....|..
gi 505180171 310 SMPLVLKTVSQAAWQAGAAVRLDV-IGQARIF 340
Cdd:COG3842  320 ELVVRVPNRAALPLEPGDRVGLSWdPEDVVVL 351
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 2-342 2.10e-118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 345.59  E-value: 2.10e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFaegVFVPAHQRGIGF 81
Cdd:COG1118    3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF---TNLPPRERRVGF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:COG1118   80 VFQHYALFPHMTVAENIAFGLRVrppSKAEIRARVEELLELVQLEG-LADRYPSQLSGGQRQRVALARALAVEPEVLLLD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:COG1118  159 EPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVN 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 239 VLDAELMEGRARCAIGELPTDDPHANGRGRVMLRPEQLRVSSCAPQESAF--RIVDVDFAGHISTLTVSAAGQSMPLVLK 316
Cdd:COG1118  239 VLRGRVIGGQLEADGLTLPVAEPLPDGPAVAGVRPHDIEVSREPEGENTFpaTVARVSELGPEVRVELKLEDGEGQPLEA 318

                        330       340       350
                 ....*....|....*....|....*....|.
gi 505180171 317 TVSQAAW-----QAGAAVRLdVIGQARIFCA 342
Cdd:COG1118  319 EVTKEAWaelglAPGDPVYL-RPRPARVFLP 348
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-333 1.86e-104

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 310.08  E-value: 1.86e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG---NTLfaegvfvPAHQR 77
Cdd:COG3839    3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGrdvTDL-------PPKDR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALDATLASHwPHEISGGQQQRVALARALAQRPSL 154
Cdd:COG3839   76 NIAMVFQSYALYPHMTVYENIAFPLklrKVPKAEIDRRVREAAELLGLEDLLDRK-PKQLSGGQRQRVALGRALVREPKV 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 155 MLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFL 234
Cdd:COG3839  155 FLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFI 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 235 GD--ALVLDAELMEGRARCAIGELPTDD---PHANGRGRVMLRPEQLRVSSCAPQESAFRIVDVDFAGHISTLTVSAAGQ 309
Cdd:COG3839  235 GSppMNLLPGTVEGGGVRLGGVRLPLPAalaAAAGGEVTLGIRPEHLRLADEGDGGLEATVEVVEPLGSETLVHVRLGGQ 314

                        330       340
                 ....*....|....*....|....
gi 505180171 310 smPLVLKTVSQAAWQAGAAVRLDV 333
Cdd:COG3839  315 --ELVARVPGDTRLRPGDTVRLAF 336
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 2-216 4.93e-98

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 288.65  E-value: 4.93e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIGF 81
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG----VPPERRNIGM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03259   77 VFQDYALFPHLTVAENIAFGLKlrgVPKAEIRARVRELLELVGLEG-LLNRYPHELSGGQQQRVALARALAREPSLLLLD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03259  156 EPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-278 2.52e-88

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 269.89  E-value: 2.52e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIGF 81
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI----THVPAENRHVNT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK09452  91 VFQSYALFPHMTVFENVAFGLRMqktPAAEITPRVMEALRMVQLEE-FAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:PRK09452 170 ESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEIN 249

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 505180171 239 VLDAE----LMEGRARCAIGELP----TDDPHANGRG-RVMLRPEQLRV 278
Cdd:PRK09452 250 IFDATvierLDEQRVRANVEGREcniyVNFAVEPGQKlHVLLRPEDLRV 298
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 2-235 1.39e-87

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 262.94  E-value: 1.39e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIGF 81
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITN----LPPHKRPVNT 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03300   77 VFQNYALFPHLTVFENIAFGLrlkKLPKAEIKERVAEALDLVQLEG-YANRKPSQLSGGQQQRVAIARALVNEPKVLLLD 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLG 235
Cdd:cd03300  156 EPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 2-236 1.95e-82

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 249.95  E-value: 1.95e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaEGVFVPAHQRGIGF 81
Cdd:cd03296    3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGE----DATDVPVQERNVGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGL-------DCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:cd03296   79 VFQHYALFRHMTVFDNVAFGLrvkprseRPPEAEIRAKVHELLKLVQLDW-LADRYPAQLSGGQRQRVALARALAVEPKV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 155 MLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFL 234
Cdd:cd03296  158 LLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFL 237


                 ..
gi 505180171 235 GD 236
Cdd:cd03296  238 GE 239
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 2-310 5.96e-82

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 253.04  E-value: 5.96e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIGF 81
Cdd:TIGR03265   5 LSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDI----TRLPPQKRDYGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   82 VPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR03265  81 VFQSYALFPNLTVADNIAYGLKnrgMGRAEVAERVAELLDLVGLP-GSERKYPGQLSGGQQQRVALARALATSPGLLLLD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:TIGR03265 160 EPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVN 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171  239 VLDAELMEG-RARCAIGELPTDD--PHANGRGRVMLRPEQLRVSSCAPQESAF--RIVDVDFAGHISTLTVSAAGQS 310
Cdd:TIGR03265 240 WLPGTRGGGsRARVGGLTLACAPglAQPGASVRLAVRPEDIRVSPAGNAANLLlaRVEDMEFLGAFYRLRLRLEGLP 316
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-221 7.31e-78

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 239.22  E-value: 7.31e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfVPAHQ 76
Cdd:COG1116    7 ALELRGVSKRFPTGgggvTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKP-------VTGPG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG1116   80 PDRGVVFQEPALLPWLTVLDNVALGLElrgVPKAERRERARELLELVGLAG-FEDAYPHQLSGGMRQRVAIARALANDPE 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRqGRFAQVGTPFEV 221
Cdd:COG1116  159 VLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLS-ARPGRIVEEIDV 225
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 2-215 1.75e-77

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 236.60  E-value: 1.75e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqgntlfaEGVFVPAHQR 77
Cdd:cd03293    1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLV-------DGEPVTGPGP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:cd03293   74 DRGYVFQQDALLPWLTVLDNVALGLELqgvPKAEARERAEELLELVGLSGF-ENAYPHQLSGGMRQRVALARALAVDPDV 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 155 MLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVM--RQGRFAQV 215
Cdd:cd03293  153 LLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLsaRPGRIVAE 215
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
2-308 2.22e-76

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 238.44  E-value: 2.22e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIGF 81
Cdd:PRK10851   3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSR----LHARDRKVGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLDC-------SREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:PRK10851  79 VFQHYALFRHMTVFDNIAFGLTVlprrerpNAAAIKAKVTQLLEMVQL-AHLADRYPAQLSGGQKQRVALARALAVEPQI 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 155 MLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFL 234
Cdd:PRK10851 158 LLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFM 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 235 GDALVLDAELMEGRARCAIGELPTD-DPHANGRGRVMLRPEQLRVSscaPQESAF-----RIVDVDFAGHISTLTVSAAG 308
Cdd:PRK10851 238 GEVNRLQGTIRGGQFHVGAHRWPLGyTPAYQGPVDLFLRPWEVDIS---RRTSLDsplpvQVLEVSPKGHYWQLVVQPLG 314
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 2-240 2.28e-76

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 234.69  E-value: 2.28e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaEGVFVPAHQRGIGF 81
Cdd:TIGR00968   1 IEIANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQ----DATRVHARDRKIGF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   82 VPQEGALFPHLNVADNIAWGLDCSR---EEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR00968  77 VFQHYALFKHLTVRDNIAFGLEIRKhpkAKIKARVEELLELVQL-EGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLD 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:TIGR00968 156 EPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVN 235


                  ..
gi 505180171  239 VL 240
Cdd:TIGR00968 236 VL 237
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2-313 5.00e-76

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 237.70  E-value: 5.00e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVfvpaHQRGIGF 81
Cdd:PRK11432   7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSI----QQRDICM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK11432  83 VFQSYALFPHMSLGENVGYGLkmlGVPKEERKQRVKEALELVDL-AGFEDRYVDQISGGQQQRVALARALILKPKVLLFD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:PRK11432 162 EPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDAN 241

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 239 VLDAELMEGRARCAIGELPTDD----PHANGRGRVMLRPEQLRVSSCAPQESAFRIVDVDFAGHISTLTVSAAGQSMPL 313
Cdd:PRK11432 242 IFPATLSGDYVDIYGYRLPRPAafafNLPDGECTVGVRPEAITLSEQGEESQRCTIKHVAYMGPQYEVTVDWHGQELLL 320
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 32-287 1.51e-75

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 235.47  E-value: 1.51e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   32 IVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIGFVPQEGALFPHLNVADNIAWGL---DCSREE 108
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV----TNVPPHLRHINMVFQSYALFPHMTVEENVAFGLkmrKVPRAE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  109 KRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASI 188
Cdd:TIGR01187  77 IKPRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  189 LVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDALVLDAELME--GRARCAIGELP------TDD 260
Cdd:TIGR01187 156 FVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATVIErkSEQVVLAGVEGrrcdiyTDV 235

                         250       260
                  ....*....|....*....|....*...
gi 505180171  261 P-HANGRGRVMLRPEQLRVSSCAPQESA 287
Cdd:TIGR01187 236 PvEKDQPLHVVLRPEKIVIEEEDEANSS 263
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 1-235 1.47e-74

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 232.29  E-value: 1.47e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQ--R 77
Cdd:COG1125    1 MIEFENVTKRYPDGtVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRD----LDPVElrR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIA-------WgldcSREEKRRRVAALMEMVALD-ATLASHWPHEISGGQQQRVALARALA 149
Cdd:COG1125   77 RIGYVIQQIGLFPHMTVAENIAtvprllgW----DKERIRARVDELLELVGLDpEEYRDRYPHELSGGQQQRVGVARALA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 150 QRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEA 229
Cdd:COG1125  153 ADPPILLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDF 232


                 ....*.
gi 505180171 230 TALFLG 235
Cdd:COG1125  233 VADFVG 238
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 2-216 5.41e-73

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 225.21  E-value: 5.41e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIGF 81
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV----TDLPPKDRDIAM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALDATLaSHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03301   77 VFQNYALYPHMTVYDNIAFGLklrKVPKDEIDERVREVAELLQIEHLL-DRKPKQLSGGQRQRVALGRAIVREPKVFLMD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03301  156 EPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
1-246 2.67e-72

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 228.95  E-value: 2.67e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIG 80
Cdd:PRK11607  19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDL----SHVPPYQRPIN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK11607  95 MMFQSYALFPHMTVEQNIAFGLKqdkLPKAEIASRVNEMLGLVHMQ-EFAKRKPHQLSGGQRQRVALARSLAKRPKLLLL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDA 237
Cdd:PRK11607 174 DEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSV 253


                 ....*....
gi 505180171 238 LVLDAELME 246
Cdd:PRK11607 254 NVFEGVLKE 262
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 1-235 1.81e-71

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 221.79  E-value: 1.81e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIG 80
Cdd:COG1126    1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINKLRRKVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDC----SREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:COG1126   81 MVFQQFNLFPHLTVLENVTLAPIKvkkmSKAEAEERAMELLERVGL-ADKADAYPAQLSGGQQQRVAIARALAMEPKVML 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 157 LDEPFSALD---TG-----LRAatrkatadlLAEAGVASILVTHDqteaLSFASQVA----VMRQGRFAQVGTPFEVYSR 224
Cdd:COG1126  160 FDEPTSALDpelVGevldvMRD---------LAKEGMTMVVVTHE----MGFAREVAdrvvFMDGGRIVEEGPPEEFFEN 226

                        250
                 ....*....|.
gi 505180171 225 PVDEATALFLG 235
Cdd:COG1126  227 PQHERTRAFLS 237
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 2-235 3.42e-71

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 221.06  E-value: 3.42e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADaLVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQRGIGF 81
Cdd:cd03299    1 LKVENLSKDWKE-FKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI----TNLPPEKRDISY 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALDATLaSHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03299   76 VPQNYALFPHMTVYKNIAYGLkkrKVDKKEIERKVLEIAEMLGIDHLL-NRKPETLSGGEQQRVAIARALVVNPKILLLD 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLG 235
Cdd:cd03299  155 EPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLG 231
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 17-216 3.16e-70

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 217.93  E-value: 3.16e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVA---PGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLF--AEGVFVPAHQRGIGFVPQEGALFPH 91
Cdd:cd03297   10 LPDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFdsRKKINLPPQQRKIGLVFQQYALFPH 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 LNVADNIAWGLD-CSREEKRRRVAALMEMVALDATLASHwPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:cd03297   90 LNVRENLAFGLKrKRNREDRISVDELLDLLGLDHLLNRY-PAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRL 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 505180171 171 ATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03297  169 QLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 1-319 7.31e-68

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 216.89  E-value: 7.31e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSsISKSFADaLVLDnLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLF--AEGVFVPAHQRG 78
Cdd:COG4148    2 MLEVD-FRLRRGG-FTLD-VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQdsARGIFLPPHRRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGL-DCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG4148   79 IGYVFQEARLFPHLSVRGNLLYGRkRAPRAERRISFDEVVELLGI-GHLLDRRPATLSGGERQRVAIGRALLSSPRLLLM 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 158 DEPFSALDtglraATRKatADLL-------AEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEAT 230
Cdd:COG4148  158 DEPLAALD-----LARK--AEILpylerlrDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPL 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 231 ALFLGDALVLDAELME-----GRARCAIGE----LPTDDPHANGRGR-------VML---RPEQL--------RVSSCAP 283
Cdd:COG4148  231 AGGEEAGSVLEATVAAhdpdyGLTRLALGGgrlwVPRLDLPPGTRVRvrirardVSLalePPEGSsilnilpgRVVEIEP 310

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 505180171 284 QESAFRIVDVDFAGH--ISTLTVSAA-------GQSMPLVLKTVS 319
Cdd:COG4148  311 ADGGQVLVRLDLGGQtlLARITRRSAdelglapGQTVYAQIKSVA 355
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 2-235 9.75e-67

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 210.23  E-value: 9.75e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFAD-ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGVfvpAHQRGI 79
Cdd:cd03295    1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGeDIREQDPV---ELRRKI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGALFPHLNVADNIA-------WgldcSREEKRRRVAALMEMVALD-ATLASHWPHEISGGQQQRVALARALAQR 151
Cdd:cd03295   78 GYVIQQIGLFPHMTVEENIAlvpkllkW----PKEKIRERADELLALVGLDpAEFADRYPHELSGGQQQRVGVARALAAD 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 152 PSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATA 231
Cdd:cd03295  154 PPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVA 233


                 ....
gi 505180171 232 LFLG 235
Cdd:cd03295  234 EFVG 237
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 1-218 7.03e-65

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 205.21  E-value: 7.03e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG---NTLFAEGVFvpAHQR 77
Cdd:COG1127    5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGqdiTGLSEKELY--ELRR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG1127   83 RIGMLFQGGALFDSLTVFENVAFPLrehtDLSEAEIRELVLEKLELVGLPGA-ADKMPSELSGGMRKRVALARALALDPE 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 154 LMLLDEPFSALDtglrAATRKATADLLAE----AGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTP 218
Cdd:COG1127  162 ILLYDEPTAGLD----PITSAVIDELIRElrdeLGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTP 226
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-243 1.54e-64

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 212.46  E-value: 1.54e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA-----DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA-EGVFVPA 74
Cdd:COG1123  260 LLEVRNLSKRYPvrgkgGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKlSRRSLRE 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRGIGFVPQ--EGALFPHLNVADNIAWGLD----CSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARAL 148
Cdd:COG1123  340 LRRRVQMVFQdpYSSLNPRMTVGDIIAEPLRlhglLSRAERRERVAELLERVGLPPDLADRYPHELSGGQRQRVAIARAL 419

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 149 AQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDE 228
Cdd:COG1123  420 ALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQHP 499

                        250
                 ....*....|....*
gi 505180171 229 ATALFLGDALVLDAE 243
Cdd:COG1123  500 YTRALLAAVPSLDPA 514
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 2-211 2.78e-64

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 201.65  E-value: 2.78e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIGF 81
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRRRIGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLdcsreekrrrvaalmemvaldatlashwpheiSGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03229   81 VFQDFALFPHLTVLENIALGL--------------------------------SGGQQQRVALARALAMDPDVLLLDEPT 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505180171 162 SALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03229  129 SALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1-235 4.83e-62

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 197.67  E-value: 4.83e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVldNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIG 80
Cdd:COG3840    1 MLRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTA----LPPAERPVS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDCS---REEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3840   75 MLFQENNLFPHLTVAQNIGLGLRPGlklTAEQRAQVEQALERVGL-AGLLDRLPGQLSGGQRQRVALARCLVRKRPILLL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLG 235
Cdd:COG3840  154 DEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLG 231
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-211 9.94e-62

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 196.80  E-value: 9.94e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADAL----VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQ 76
Cdd:COG1136    4 LLELRNLTKSYGTGEgevtALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISS----LSERE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RG------IGFVPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARA 147
Cdd:COG1136   80 LArlrrrhIGFVFQFFNLLPELTALENVALPLLlagVSRKERRERARELLERVGLGD-RLDHRPSQLSGGQQQRVAIARA 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 148 LAQRPSLMLLDEPFSALDTglraATRKATADLL----AEAGVASILVTHDQtEALSFASQVAVMRQGR 211
Cdd:COG1136  159 LVNRPKLILADEPTGNLDS----KTGEEVLELLrelnRELGTTIVMVTHDP-ELAARADRVIRLRDGR 221
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 1-243 6.61e-61

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 195.41  E-value: 6.61e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADAL----VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQ 76
Cdd:COG1124    1 MLEVRNLSVSYGQGGrrvpVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPV--TRRRRKAFR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQ--EGALFPHLNVADNIAWGLDCSRE-EKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG1124   79 RRVQMVFQdpYASLHPRHTVDRILAEPLRIHGLpDREERIAELLEQVGLPPSFLDRYPHQLSGGQRQRVAIARALILEPE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALF 233
Cdd:COG1124  159 LLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKHPYTREL 238

                        250
                 ....*....|
gi 505180171 234 LGDALVLDAE 243
Cdd:COG1124  239 LAASLAFERA 248
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 2-221 2.19e-59

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 190.79  E-value: 2.19e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfvPAHQ----R 77
Cdd:cd03261    1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLS---EAELyrlrR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:cd03261   78 RMGMLFQSGALFDSLTVFENVAFPLrehtRLSEEEIREIVLEKLEAVGLRGA-EDLYPAELSGGMKKRVALARALALDPE 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:cd03261  157 LLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-283 8.06e-59

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 193.52  E-value: 8.06e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSF-ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG---NTLfaEgvfvPAhQ 76
Cdd:PRK11650   3 GLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGrvvNEL--E----PA-D 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDATLASHwPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK11650  76 RDIAMVFQNYALYPHMSVRENMAYGLKirgMPKAEIEERVAEAARILELEPLLDRK-PRELSGGQRQRVAMGRAIVREPA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALF 233
Cdd:PRK11650 155 VFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASF 234

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 234 LG-------DALVLDAELMEGRARCAIGELPTDDPHANGRGRVM-LRPEQLRVSSCAP 283
Cdd:PRK11650 235 IGspamnllDGRVSADGAAFELAGGIALPLGGGYRQYAGRKLTLgIRPEHIALSSAEG 292
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 2-211 1.79e-57

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 185.39  E-value: 1.79e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQR 77
Cdd:cd03255    1 IELKNLSKTYGGGgekvQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 G--IGFVPQEGALFPHLNVADNIAWGLDCS---REEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRP 152
Cdd:cd03255   81 RrhIGFVFQSFNLLPDLTALENVELPLLLAgvpKKERRERAEELLERVGLGD-RLNHYPSELSGGQQQRVAIARALANDP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 153 SLMLLDEPFSALDTglraATRKATADLL----AEAGVASILVTHDQtEALSFASQVAVMRQGR 211
Cdd:cd03255  160 KIILADEPTGNLDS----ETGKEVMELLrelnKEAGTTIVVVTHDP-ELAEYADRIIELRDGK 217
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1-234 3.08e-57

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 185.68  E-value: 3.08e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIG 80
Cdd:PRK09493   1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWG----LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK09493  81 MVFQQFYLFPHLTALENVMFGplrvRGASKEEAEKQARELLAKVGL-AERAHHYPSELSGGQQQRVAIARALAVKPKLML 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 157 LDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFL 234
Cdd:PRK09493 160 FDEPTSALDPELRHEVLKVMQD-LAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFL 236
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
4-235 4.12e-57

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 189.47  E-value: 4.12e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   4 LSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqGNTLFAEgvfVPAHQRGIGFVP 83
Cdd:PRK11000   6 LRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFI-GEKRMND---VPPAERGVGMVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  84 QEGALFPHLNVADNIAWGLDCSREEK---RRRVAALMEMVALDATLASHwPHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:PRK11000  82 QSYALYPHLSVAENMSFGLKLAGAKKeeiNQRVNQVAEVLQLAHLLDRK-PKALSGGQRQRVAIGRTLVAEPSVFLLDEP 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 161 FSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLG 235
Cdd:PRK11000 161 LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIG 235
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
2-250 4.65e-57

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 184.88  E-value: 4.65e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHqrgIGF 81
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRR---IGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNI---AWGLDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:COG1131   78 VPQEPALYPDLTVRENLrffARLYGLPRKEARERIDELLELFGLTD-AADRKVGTLSGGMKQRLGLALALLHDPELLILD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 159 EPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPfevysrpvDEATALFLGDAL 238
Cdd:COG1131  157 EPTSGLDPEARRELWELLRE-LAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTP--------DELKARLLEDVF 227

                        250
                 ....*....|..
gi 505180171 239 VldaELMEGRAR 250
Cdd:COG1131  228 L---ELTGEEAR 236
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 2-225 1.82e-56

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 183.30  E-value: 1.82e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfVPAHQRGIG 80
Cdd:COG1122    1 IELENLSFSYPGGtPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKN--LRELRRKVG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQ--EGALFpHLNVADNIAWG---LDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG1122   79 LVFQnpDDQLF-APTVEEDVAFGpenLGLPREEIRERVEEALELVGLEH-LADRPPHELSGGQKQRVAIAGVLAMEPEVL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 156 LLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:COG1122  157 VLDEPTAGLD----PRGRRELLELLKRlnkEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 2-211 5.46e-56

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 181.57  E-value: 5.46e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIGF 81
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINELRQKVGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIA----WGLDCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:cd03262   81 VFQQFNLFPHLTVLENITlapiKVKGMSKAEAEERALELLEKVGLADK-ADAYPAQLSGGQQQRVAIARALAMNPKVMLF 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 505180171 158 DEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03262  160 DEPTSALDPELVGEVLDVMKD-LAEEGMTMVVVTHEMGFAREVADRVIFMDDGR 212
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-230 9.10e-55

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 179.51  E-value: 9.10e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfvPAHQRG-I 79
Cdd:COG1121    6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKP--------PRRARRrI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGAL---FPhLNVADNIAWGLDCSR-------EEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALA 149
Cdd:COG1121   78 GYVPQRAEVdwdFP-ITVRDVVLMGRYGRRglfrrpsRADREAVDEALERVGLED-LADRPIGELSGGQQQRVLLARALA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 150 QRPSLMLLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGRFAQvGTPFEVYSRPV 226
Cdd:COG1121  156 QDPDLLLLDEPFAGVD----AATEEALYELLRElrrEGKTILVVTHDLGAVREYFDRVLLLNRGLVAH-GPPEEVLTPEN 230


                 ....
gi 505180171 227 DEAT 230
Cdd:COG1121  231 LSRA 234
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 1-204 1.00e-54

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 178.06  E-value: 1.00e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPD---NGRIVLQGNTLFAegvfVPAHQR 77
Cdd:COG4136    1 MLSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTA----LPAEQR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIAWGL--DCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG4136   77 RIGILFQDDLLFPHLSVGENLAFALppTIGRAQRRARVEQALEEAGL-AGFADRDPATLSGGQRARVALLRALLAEPRAL 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 505180171 156 LLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSfASQV 204
Cdd:COG4136  156 LLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPA-AGRV 203
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 1-211 2.10e-54

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 177.70  E-value: 2.10e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADAL----VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGVFVPAH 75
Cdd:cd03257    1 LLEVKNLSVSFPTGGgsvkALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGkDLLKLSRRLRKIR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  76 QRGIGFVPQE--GALFPHLNVADNIA-----WGLDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARAL 148
Cdd:cd03257   81 RKEIQMVFQDpmSSLNPRMTIGEQIAeplriHGKLSKKEARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQRVAIARAL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 149 AQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03257  161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGK 223
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
2-212 2.81e-54

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 176.93  E-value: 2.81e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGF 81
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPL--SAMPPPEWRRQVAY 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHlNVADNIA-WGLDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:COG4619   79 VPQEPALWGG-TVRDNLPfPFQLRERKFDRERALELLERLGLPPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEP 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 505180171 161 FSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRF 212
Cdd:COG4619  158 TSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-242 6.71e-54

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 179.89  E-value: 6.71e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQ 76
Cdd:COG1135    1 MIELENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTA----LSERE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 -----RGIGFVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARAL 148
Cdd:COG1135   77 lraarRKIGMIFQHFNLLSSRTVAENVALPLEIagvPKAEIRKRVAELLELVGLSD-KADAYPSQLSGGQKQRVGIARAL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 149 AQRPSLMLLDEPFSALDtglrAATRKATADLLAEA----GVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:COG1135  156 ANNPKVLLCDEATSALD----PETTRSILDLLKDInrelGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFAN 231

                        250
                 ....*....|....*...
gi 505180171 225 PVDEATALFLGDALVLDA 242
Cdd:COG1135  232 PQSELTRRFLPTVLNDEL 249
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 20-226 2.40e-53

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 179.15  E-value: 2.40e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   20 LNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLF--AEGVFVPAHQRGIGFVPQEGALFPHLNVADN 97
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFdsRKGIFLPPEKRRIGYVFQEARLFPHLSVRGN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   98 IAWGL-DCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKAT 176
Cdd:TIGR02142  96 LRYGMkRARPSERRISFERVIELLGIGH-LLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPYL 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 505180171  177 ADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPV 226
Cdd:TIGR02142 175 ERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPD 224
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 3-211 6.88e-53

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 173.42  E-value: 6.88e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADA--LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFvpAHQRGIG 80
Cdd:cd03225    1 ELKNLSFSYPDGarPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLK--ELRRKVG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQ--EGALFpHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:cd03225   79 LVFQnpDDQFF-GPTVEEEVAFGLEnlgLPEEEIEERVEEALELVGLEG-LRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 156 LLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03225  157 LLDEPTAGLD----PAGRRELLELLKKlkaEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 1-221 1.35e-52

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 174.08  E-value: 1.35e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRG-- 78
Cdd:COG1120    1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLAS----LSRRELArr 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWG-------LDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQR 151
Cdd:COG1120   77 IAYVPQEPPAPFGLTVRELVALGryphlglFGRPSAEDREAVEEALERTGLEH-LADRPVDELSGGERQRVLIARALAQE 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 152 PSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:COG1120  156 PPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-215 2.41e-52

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 173.51  E-value: 2.41e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSF----ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGvfvPAHQ 76
Cdd:COG4525    3 MLTVRHVSVRYpgggQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPV--TG---PGAD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFvpQEGALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG4525   78 RGVVF--QKDALLPWLNVLDNVAFGLRlrgVPKAERRARAEELLALVGLAD-FARRRIWQLSGGMRQRVGIARALAADPR 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 154 LMLLDEPFSALDtglrAATRKATADLL----AEAGVASILVTHDQTEALSFASQVAVM--RQGRFAQV 215
Cdd:COG4525  155 FLLMDEPFGALD----ALTREQMQELLldvwQRTGKGVFLITHSVEEALFLATRLVVMspGPGRIVER 218
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 1-228 4.45e-51

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 169.65  E-value: 4.45e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgvfVPAHQRGIG 80
Cdd:COG4555    1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKE---PREARRQIG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNI-----AWGLdcSREEKRRRVAALMEMVALDATLASHWpHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG4555   78 VLPDERGLYDRLTVRENIryfaeLYGL--FDEELKKRIEELIELLGLEEFLDRRV-GELSTGMKKKVALARALVHDPKVL 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 156 LLDEPFSALDTGlraATRKATADL--LAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDE 228
Cdd:COG4555  155 LLDEPTNGLDVM---ARRLLREILraLKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEE 226
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 1-225 1.59e-50

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 168.14  E-value: 1.59e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFAD----ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG--NTLFAEGVFVPA 74
Cdd:cd03258    1 MIELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGtdLTLLSGKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRgIGFVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQR 151
Cdd:cd03258   81 RRR-IGMIFQHFNLLSSRTVFENVALPLEIagvPKAEIEERVLELLELVGL-EDKADAYPAQLSGGQKQRVGIARALANN 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 152 PSLMLLDEPFSALDtglrAATRKATADLL----AEAGVASILVTHdQTEAL-SFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:cd03258  159 PKVLLCDEATSALD----PETTQSILALLrdinRELGLTIVLITH-EMEVVkRICDRVAVMEKGEVVEEGTVEEVFANP 232
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1-211 1.82e-50

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 167.54  E-value: 1.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA-DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG---NTLFAEGVfvPAHQ 76
Cdd:COG2884    1 MIRFENVSKRYPgGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGqdlSRLKRREI--PYLR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG2884   79 RRIGVVFQDFRLLPDRTVYENVALPLRVtgkSRKEIRRRVREVLDLVGL-SDKAKALPHELSGGEQQRVAIARALVNRPE 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 154 LMLLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:COG2884  158 LLLADEPTGNLD----PETSWEIMELLEEinrRGTTVLIATHDLELVDRMPKRVLELEDGR 214
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 19-236 2.02e-50

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 168.98  E-value: 2.02e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  19 NLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL--FAEGVFVPAHQRGIGFVPQEGALFPHLNVAD 96
Cdd:cd03294   42 DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIaaMSRKELRELRRKKISMVFQSFALLPHRTVLE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  97 NIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATR 173
Cdd:cd03294  122 NVAFGLEVqgvPRAEREERAAEALELVGLEG-WEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQ 200

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 174 KATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGD 236
Cdd:cd03294  201 DELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRG 263
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 2-212 5.63e-50

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 164.49  E-value: 5.63e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHqrgIGF 81
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRR---IGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIawgldcsreekrrrvaalmemvaldatlashwphEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03230   78 LPEEPSLYENLTVRENL----------------------------------KLSGGMKQRLALAQALLHDPELLILDEPT 123

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 505180171 162 SALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRF 212
Cdd:cd03230  124 SGLDPESRREFWELLRE-LKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-249 5.64e-49

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 171.62  E-value: 5.64e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA--DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDNGRIvlQGNTLFA--EGVFVPAHQ 76
Cdd:COG1123    4 LLEVRDLSVRYPggDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGL-LPHGGRI--SGEVLLDgrDLLELSEAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RG--IGFVPQE--GALFPhLNVADNIAWGL---DCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALA 149
Cdd:COG1123   81 RGrrIGMVFQDpmTQLNP-VTVGDQIAEALenlGLSRAEARARVLELLEAVGLER-RLDRYPHQLSGGQRQRVAIAMALA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 150 QRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEA 229
Cdd:COG1123  159 LDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQALA 238

                        250       260
                 ....*....|....*....|
gi 505180171 230 TALFLGDALVLDAELMEGRA 249
Cdd:COG1123  239 AVPRLGAARGRAAPAAAAAE 258
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 1-211 7.94e-49

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 164.07  E-value: 7.94e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA-EGVFVPAHQRG 78
Cdd:COG3638    2 MLELRNLSKRYPGGtPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTAlRGRALRRLRRR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNI-------------AWGLdCSREEKRRRVAALmEMVALdATLASHWPHEISGGQQQRVALA 145
Cdd:COG3638   82 IGMIFQQFNLVPRLSVLTNVlagrlgrtstwrsLLGL-FPPEDRERALEAL-ERVGL-ADKAYQRADQLSGGQQQRVAIA 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 146 RALAQRPSLMLLDEPFSALDtglRAATRKATADLLAEA---GVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:COG3638  159 RALVQEPKLILADEPVASLD---PKTARQVMDLLRRIAredGITVVVNLHQVDLARRYADRIIGLRDGR 224
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 2-218 9.58e-49

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 163.12  E-value: 9.58e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDNGRIVLQGNTLFAEGVFVPAHQ 76
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDIYDLDVDVLELR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPhLNVADNIAWGL----DCSREEKRRRVAALMEMVALDATLASH-WPHEISGGQQQRVALARALAQR 151
Cdd:cd03260   81 RRVGMVFQKPNPFP-GSIYDNVAYGLrlhgIKLKEELDERVEEALRKAALWDEVKDRlHALGLSGGQQQRLCLARALANE 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 152 PSLMLLDEPFSALDtglRAATRKaTADLLAEAG--VASILVTHDQTEALSFASQVAVMRQGRFAQVGTP 218
Cdd:cd03260  160 PEVLLLDEPTSALD---PISTAK-IEELIAELKkeYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPT 224
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 17-162 1.50e-48

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 160.12  E-value: 1.50e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfVPAHQRGIGFVPQEGALFPHLNVAD 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE--RKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171   97 NIAWGLDC---SREEKRRRVAALMEMVALDATLASHW---PHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:pfam00005  79 NLRLGLLLkglSKREKDARAEEALEKLGLGDLADRPVgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 9-249 3.24e-48

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 165.80  E-value: 3.24e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    9 KSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLF--AEGVFVPAHQRGIGFVPQEG 86
Cdd:TIGR01186   1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMkqSPVELREVRRKKIGMVFQQF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   87 ALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:TIGR01186  81 ALFPHMTILQNTSLGPELlgwPEQERKEKALELLKLVGLEE-YEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  164 LDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGD---ALVL 240
Cdd:TIGR01186 160 LDPLIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGKvdlSQVF 239


                  ....*....
gi 505180171  241 DAELMEGRA 249
Cdd:TIGR01186 240 DAERIAQRM 248
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 17-225 6.74e-48

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 162.62  E-value: 6.74e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRG-IGFVPQ--EGALFpHLN 93
Cdd:TIGR04521  21 LDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKDLRKkVGLVFQfpEHQLF-EET 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   94 VADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrA 170
Cdd:TIGR04521 100 VYKDIAFGpknLGLSEEEAEERVKEALELVGLDEEYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPTAGLD----P 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171  171 ATRKATADLLA----EAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:TIGR04521 176 KGRKEILDLFKrlhkEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 20-216 8.97e-48

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 160.35  E-value: 8.97e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  20 LNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfAEGVFVPAHQRGIGFVPQEGALFPHLNVADNIA 99
Cdd:cd03298   17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLING----VDVTAAPPADRPVSMLFQENNLFAHLTVEQNVG 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 100 WGLDCS---REEKRRRVAALMEMVALDATLAsHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKAT 176
Cdd:cd03298   93 LGLSPGlklTAEDRQAIEVALARVGLAGLEK-RLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLV 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 505180171 177 ADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03298  172 LDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 1-197 2.14e-46

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 157.21  E-value: 2.14e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA---EGVfvp 73
Cdd:COG4181    8 IIELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFAldeDAR--- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  74 AHQRG--IGFVPQEGALFPHLNVADNIAWGLD-CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQ 150
Cdd:COG4181   85 ARLRArhVGFVFQSFQLLPTLTALENVMLPLElAGRRDARARARALLERVGLGH-RLDHYPAQLSGGEQQRVALARAFAT 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 505180171 151 RPSLMLLDEPfsaldTG-LRAATRKATADLL----AEAGVASILVTHDQTEA 197
Cdd:COG4181  164 EPAILFADEP-----TGnLDAATGEQIIDLLfelnRERGTTLVLVTHDPALA 210
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1-295 2.16e-46

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 164.04  E-value: 2.16e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEgvfvP--AHQR 77
Cdd:COG1129    4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVrFRS----PrdAQAA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNI--------AWGLDcsREEKRRRVAALMEMVALD---ATLAShwphEISGGQQQRVALAR 146
Cdd:COG1129   80 GIAIIHQELNLVPNLSVAENIflgreprrGGLID--WRAMRRRARELLARLGLDidpDTPVG----DLSVAQQQLVEIAR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 147 ALAQRPSLMLLDEPFSALdtglraaTRKATADL------LAEAGVASILVTHDQTEALSFASQVAVMRQGRFaqVGTpfe 220
Cdd:COG1129  154 ALSRDARVLILDEPTASL-------TEREVERLfriirrLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL--VGT--- 221

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 221 vysRPVDEATAlflgDALVldaELMEGRarcAIGELPTDDPHAngRGRVMLRPEQLRVsscapqESAFRivDVDF 295
Cdd:COG1129  222 ---GPVAELTE----DELV---RLMVGR---ELEDLFPKRAAA--PGEVVLEVEGLSV------GGVVR--DVSF 273
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 1-197 2.04e-45

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 153.79  E-value: 2.04e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfvPAHQRGIG 80
Cdd:COG4133    2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAR---EDYRRRLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAW-----GLDCSREekrrRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG4133   79 YLGHADGLKPELTVRENLRFwaalyGLRADRE----AIDEALEAVGLAG-LADLPVRQLSAGQKRRVALARLLLSPAPLW 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 505180171 156 LLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEA 197
Cdd:COG4133  154 LLDEPFTALD----AAGVALLAELIAAhlaRGGAVLLTTHQPLEL 194
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 2-225 7.24e-45

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 153.36  E-value: 7.24e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfAEGVFVPAHQR---G 78
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDG----EDITGLPPHEIarlG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNI-------------AWGLDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALA 145
Cdd:cd03219   77 IGRTFQIPRLFPELTVLENVmvaaqartgsgllLARARREEREARERAEELLERVGLAD-LADRPAGELSYGQQRRLEIA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 146 RALAQRPSLMLLDEPFSaldtGLRAATRKATADL---LAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVY 222
Cdd:cd03219  156 RALATDPKLLLLDEPAA----GLNPEETEELAELireLRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVR 231


                 ...
gi 505180171 223 SRP 225
Cdd:cd03219  232 NNP 234
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
1-210 9.68e-45

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 153.70  E-value: 9.68e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegVFVPAHQRGIG 80
Cdd:PRK11248   1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKP-----VEGPGAERGVV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FvpQEGALFPHLNVADNIAWGLDCSREEKRRRVAALMEMVALD--ATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK11248  76 F--QNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVglEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLD 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 159 EPFSALDtglrAATRKATADLL----AEAGVASILVTHDQTEALSFASQVAVMRQG 210
Cdd:PRK11248 154 EPFGALD----AFTREQMQTLLlklwQETGKQVLLITHDIEEAVFMATELVLLSPG 205
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 17-227 2.29e-44

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 151.85  E-value: 2.29e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfvPAHQRGIGFvpQEGALFPHLNVAD 96
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITE-----PGPDRMVVF--QNYSLLPWLTVRE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   97 NIAWGLDC-----SREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAA 171
Cdd:TIGR01184  74 NIALAVDRvlpdlSKSERRAIVEEHIALVGLTEA-ADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGN 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171  172 TRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV-YSRPVD 227
Cdd:TIGR01184 153 LQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPRD 209
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 2-224 2.33e-44

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 161.54  E-value: 2.33e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSF--ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfaegvfVPAHQ--- 76
Cdd:COG2274  474 IELENVSFRYpgDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDG---------IDLRQidp 544

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 ----RGIGFVPQEGALFpHLNVADNIA-WGLDCSREEkrrrVAALMEMVALDATLASHwPH-----------EISGGQQQ 140
Cdd:COG2274  545 aslrRQIGVVLQDVFLF-SGTIRENITlGDPDATDEE----IIEAARLAGLHDFIEAL-PMgydtvvgeggsNLSGGQRQ 618

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 141 RVALARALAQRPSLMLLDEPFSALDtglrAATRKATADLLAE--AGVASILVTHDqTEALSFASQVAVMRQGRFAQVGTP 218
Cdd:COG2274  619 RLAIARALLRNPRILILDEATSALD----AETEAIILENLRRllKGRTVIIIAHR-LSTIRLADRIIVLDKGRIVEDGTH 693


                 ....*.
gi 505180171 219 FEVYSR 224
Cdd:COG2274  694 EELLAR 699
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 3-211 2.65e-44

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 149.32  E-value: 2.65e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegVFVPAHQRGIGFV 82
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAK--LPLEELRRRIGYV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  83 PQegalfphlnvadniawgldcsreekrrrvaalmemvaldatlashwpheISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:cd00267   79 PQ-------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 505180171 163 ALDTGLRAATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd00267  110 GLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-221 3.33e-44

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 152.50  E-value: 3.33e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQR--- 77
Cdd:COG0411    4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITG----LPPHRIarl 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIG--FvpQEGALFPHLNVADNIA------------------WGLDCSREEKRRRVAALMEMVALDAtLASHWPHEISGG 137
Cdd:COG0411   80 GIArtF--QNPRLFPELTVLENVLvaaharlgrgllaallrlPRARREEREARERAEELLERVGLAD-RADEPAGNLSYG 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 138 QQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGT 217
Cdd:COG0411  157 QQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGT 236


                 ....
gi 505180171 218 PFEV 221
Cdd:COG0411  237 PAEV 240
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
21-232 4.87e-44

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 151.27  E-value: 4.87e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  21 NLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIGFVPQEGALFPHLNVADNIAW 100
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTT----TPPSRRPVSMLFQENNLFSHLTVAQNIGL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 101 GLDCS---REEKRRRVAALMEMVALDATLaSHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATA 177
Cdd:PRK10771  95 GLNPGlklNAAQREKLHAIARQMGIEDLL-ARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVS 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 178 DLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATAL 232
Cdd:PRK10771 174 QVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLSGKASASALL 228
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 2-228 9.90e-44

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 150.80  E-value: 9.90e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADAL-VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGVFVPAHQRGI 79
Cdd:cd03256    1 IEVENLSKTYPNGKkALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDInKLKGKALRQLRRQI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGALFPHLNVADNI-------------AWGLdCSREEKRRRVAALmEMVALdATLASHWPHEISGGQQQRVALAR 146
Cdd:cd03256   81 GMIFQQFNLIERLSVLENVlsgrlgrrstwrsLFGL-FPKEEKQRALAAL-ERVGL-LDKAYQRADQLSGGQQQRVAIAR 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 147 ALAQRPSLMLLDEPFSALDtglrAATRKATADLLAEA----GVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVY 222
Cdd:cd03256  158 ALMQQPKLILADEPVASLD----PASSRQVMDLLKRInreeGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELT 233


                 ....*.
gi 505180171 223 SRPVDE 228
Cdd:cd03256  234 DEVLDE 239
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
1-234 1.92e-43

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 150.34  E-value: 1.92e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL----FAEGVFVPAHQ 76
Cdd:COG4598    8 ALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrlkpDRDGELVPADR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 R-------GIGFVPQEGALFPHLNVADNIAWG----LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALA 145
Cdd:COG4598   88 RqlqrirtRLGMVFQSFNLWSHMTVLENVIEApvhvLGRPKAEAIERAEALLAKVGL-ADKRDAYPAHLSGGQQQRAAIA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 146 RALAQRPSLMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:COG4598  167 RALAMEPEVMLFDEPTSALDPELVGEVLKVMRD-LAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNP 245


                 ....*....
gi 505180171 226 VDEATALFL 234
Cdd:COG4598  246 KSERLRQFL 254
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 1-241 3.25e-43

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 152.26  E-value: 3.25e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA--EGVFVPA 74
Cdd:PRK11153   1 MIELKNISKVFPQGgrtiHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTAlsEKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 hQRGIGFVpqegalFPHLN------VADNIAWGLDC---SREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALA 145
Cdd:PRK11153  81 -RRQIGMI------FQHFNllssrtVFDNVALPLELagtPKAEIKARVTELLELVGLSD-KADRYPAQLSGGQKQRVAIA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 146 RALAQRPSLMLLDEPFSALDTglraATRKATADLLA----EAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:PRK11153 153 RALASNPKVLLCDEATSALDP----ATTRSILELLKdinrELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEV 228

                        250       260
                 ....*....|....*....|
gi 505180171 222 YSRPVDEATALFLGDALVLD 241
Cdd:PRK11153 229 FSHPKHPLTREFIQSTLHLD 248
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-238 4.36e-43

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 149.13  E-value: 4.36e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI------VLQGNTLFAEGVFVPA 74
Cdd:PRK11264   3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditIDTARSLSQQKGLIRQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRGIGFVPQEGALFPHLNVADNIAWG----LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQ 150
Cdd:PRK11264  83 LRQHVGFVFQNFNLFPHRTVLENIIEGpvivKGEPKEEATARARELLAKVGL-AGKETSYPRRLSGGQQQRVAIARALAM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 151 RPSLMLLDEPFSALDTGLRAATRkATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEAT 230
Cdd:PRK11264 162 RPEVILFDEPTSALDPELVGEVL-NTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRT 240


                 ....*...
gi 505180171 231 ALFLGDAL 238
Cdd:PRK11264 241 RQFLEKFL 248
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 3-207 5.28e-43

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 147.68  E-value: 5.28e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgvfvpahQRGIGFV 82
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE-------RKRIGYV 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  83 PQEGAL---FPhLNVADNIAWGLDCS-------REEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRP 152
Cdd:cd03235   74 PQRRSIdrdFP-ISVRDVVLMGLYGHkglfrrlSKADKAKVDEALERVGLSE-LADRQIGELSGGQQQRVLLARALVQDP 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 153 SLMLLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVM 207
Cdd:cd03235  152 DLLLLDEPFAGVD----PKTQEDIYELLRElrrEGMTILVVTHDLGLVLEYFDRVLLL 205
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 17-228 5.80e-43

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 152.56  E-value: 5.80e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQ------RGIGFVPQEGALFP 90
Cdd:COG4175   43 VNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGEDITK----LSKKElrelrrKKMSMVFQHFALLP 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  91 HLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:COG4175  119 HRTVLENVAFGLEiqgVPKAERRERAREALELVGLAG-WEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPL 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 168 LRaatRKATADLL---AEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDE 228
Cdd:COG4175  198 IR---REMQDELLelqAKLKKTIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTNPAND 258
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 21-216 6.38e-43

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 147.70  E-value: 6.38e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   21 NLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRGIGFVPQEGALFPHLNVADNIAW 100
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTG----LAPYQRPVSMLFQENNLFAHLTVRQNIGL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  101 GLDCSRE---EKRRRVAALMEMVALDATLAsHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATA 177
Cdd:TIGR01277  94 GLHPGLKlnaEQQEKVVDAAQQVGIADYLD-RLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVK 172

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 505180171  178 DLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:TIGR01277 173 QLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
2-234 1.62e-42

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 147.47  E-value: 1.62e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGVFVPAHQ---R 77
Cdd:COG4161    3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdFSQKPSEKAIRllrQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNI----AWGLDCSREEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG4161   83 KVGMVFQQYNLWPHLTVMENLieapCKVLGLSKEQAREKAMKLLARLRLT-DKADRFPLHLSGGQQQRVAIARALMMEPQ 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPfEVYSRPVDEATALF 233
Cdd:COG4161  162 VLLFDEPTAALDPEITAQVVEIIRE-LSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDA-SHFTQPQTEAFAHY 239


                 .
gi 505180171 234 L 234
Cdd:COG4161  240 L 240
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-211 1.71e-42

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 149.10  E-value: 1.71e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegvfVPAHQRGIG 80
Cdd:COG4152    1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL------DPEDRRRIG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAW-----GLdcSREEKRRRVAALMEmvALDatLASHWPHEI---SGGQQQRVALARALAQRP 152
Cdd:COG4152   75 YLPEERGLYPKMKVGEQLVYlarlkGL--SKAEAKRRADEWLE--RLG--LGDRANKKVeelSKGNQQKVQLIAALLHDP 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 153 SLMLLDEPFSALD--------TGLRAatrkatadlLAEAGVASILVTH--DQTEALsfASQVAVMRQGR 211
Cdd:COG4152  149 ELLILDEPFSGLDpvnvellkDVIRE---------LAAKGTTVIFSSHqmELVEEL--CDRIVIINKGR 206
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
1-221 3.79e-42

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 147.18  E-value: 3.79e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaeGVFVP---AHQR 77
Cdd:COG4559    1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPL---AAWSPwelARRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIgfVPQEGAL-FPhLNVADNIAWGLD---CSREEKRRRVAALMEMVALDATLASHWPhEISGGQQQRVALARALAQ--- 150
Cdd:COG4559   78 AV--LPQHSSLaFP-FTVEEVVALGRAphgSSAAQDRQIVREALALVGLAHLAGRSYQ-TLSGGEQQRVQLARVLAQlwe 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 151 ----RPSLMLLDEPFSALDTG-----LRAATRkatadlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:COG4559  154 pvdgGPRWLFLDEPTSALDLAhqhavLRLARQ------LARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEV 227
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 2-211 1.09e-41

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 142.91  E-value: 1.09e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFAD--ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvFVPAHQRG- 78
Cdd:cd03228    1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRD---LDLESLRKn 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFpHLNVADNIawgldcsreekrrrvaalmemvaldatlashwpheISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03228   78 IAYVPQDPFLF-SGTIRENI-----------------------------------LSGGQRQRIAIARALLRDPPILILD 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVasILVTHDqTEALSFASQVAVMRQGR 211
Cdd:cd03228  122 EATSALDPETEALILEALRALAKGKTV--IVIAHR-LSTIRDADRIIVLDDGR 171
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 4-194 3.43e-41

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 142.75  E-value: 3.43e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    4 LSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGVFVPAHQRG-IGF 81
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGqETPPLNSKKASKFRREkLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   82 VPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALDATLASHwPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLkykKLSKKEKREKKKEALEKVGLNLKLKQK-IYELSGGEQQRVALARAILKPPPLILAD 159

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 505180171  159 EPFSALDTglraATRKATADLL---AEAGVASILVTHDQ 194
Cdd:TIGR03608 160 EPTGSLDP----KNRDEVLDLLlelNDEGKTIIIVTHDP 194
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 1-221 6.80e-41

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 143.76  E-value: 6.80e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaeGVFVP---AHQR 77
Cdd:PRK13548   2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPL---ADWSPaelARRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIgfVPQEGAL-FPhLNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQ--- 150
Cdd:PRK13548  79 AV--LPQHSSLsFP-FTVEEVVAMGRAphgLSRAEDDALVAAALAQVDLAH-LAGRDYPQLSGGEQQRVQLARVLAQlwe 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 151 ---RPSLMLLDEPFSALD-----TGLRAATRKAtadllAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:PRK13548 155 pdgPPRWLLLDEPTSALDlahqhHVLRLARQLA-----HERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEV 228
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 2-218 9.26e-41

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 142.19  E-value: 9.26e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQR---G 78
Cdd:cd03224    1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITG----LPPHERaraG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGL-DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:cd03224   77 IGYVPEGRRIFPELTVEENLLLGAyARRRAKRKARLERVYELFPRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLL 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 158 DEPFSaldtGLRAATRKATADL---LAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTP 218
Cdd:cd03224  157 DEPSE----GLAPKIVEEIFEAireLRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTA 216
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 2-211 1.02e-40

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 143.28  E-value: 1.02e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIvLQGNTLFAEGvfvpahQRGIGF 81
Cdd:PRK11247  13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL-LAGTAPLAEA------REDTRL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWGLdcsREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:PRK11247  86 MFQDARLLPWKKVIDNVGLGL---KGQWRDAALQALAAVGL-ADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 505180171 162 SALDtglrAATRKATADLLA----EAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:PRK11247 162 GALD----ALTRIEMQDLIEslwqQHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 1-299 1.42e-40

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 148.64  E-value: 1.42e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfvP--AHQRG 78
Cdd:COG3845    5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRS---PrdAIALG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIA------WGLDCSREEKRRRVAALMEM----VALDATLashwpHEISGGQQQRVALARAL 148
Cdd:COG3845   82 IGMVHQHFMLVPNLTVAENIVlgleptKGGRLDRKAARARIRELSERygldVDPDAKV-----EDLSVGEQQRVEILKAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 149 AQRPSLMLLDEPFSALdtglraaTRKATADL------LAEAGVASILVTHDQTEALSFASQVAVMRQGRFaqVGTpfevy 222
Cdd:COG3845  157 YRGARILILDEPTAVL-------TPQEADELfeilrrLAAEGKSIIFITHKLREVMAIADRVTVLRRGKV--VGT----- 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 223 sRPVDEATAlflgDALvldAELMEGRARcaigELPTDDPHANgRGRVMLRPEQLRVSSCAPQEsafRIVDVDF---AGHI 299
Cdd:COG3845  223 -VDTAETSE----EEL---AELMVGREV----LLRVEKAPAE-PGEVVLEVENLSVRDDRGVP---ALKDVSLevrAGEI 286
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 3-216 1.45e-40

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 140.26  E-value: 1.45e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQRG--IG 80
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLAS----LSPKELArkIA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQegALfphlnvadnIAWGLDcsrEEKRRRVaalmemvaldatlashwpHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:cd03214   77 YVPQ--AL---------ELLGLA---HLADRPF------------------NELSGGERQRVLLARALAQEPPILLLDEP 124

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 161 FSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03214  125 TSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
1-226 6.42e-40

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 143.86  E-value: 6.42e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSsISKSFADaLVLDnLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLF--AEGVFVPAHQRG 78
Cdd:PRK11144   1 MLELN-FKQQLGD-LCLT-VNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFdaEKGICLPPEKRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGLDCSREEKRRRVAALMemvALDATLaSHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK11144  78 IGYVFQDARLFPHYKVRGNLRYGMAKSMVAQFDKIVALL---GIEPLL-DRYPGSLSGGEKQRVAIGRALLTAPELLLMD 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 159 EPFSALDtglraATRKatADLLA-------EAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPV 226
Cdd:PRK11144 154 EPLASLD-----LPRK--RELLPylerlarEINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSA 221
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
1-212 6.88e-40

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 139.85  E-value: 6.88e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA----DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL----FAEGVFV 72
Cdd:NF038007   1 MLNMQNAEKCYItktiKTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVtnlsYSQKIIL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  73 paHQRGIGFVPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALA 149
Cdd:NF038007  81 --RRELIGYIFQSFNLIPHLSIFDNVALPLkyrGVAKKERIERVNQVLNLFGIDNR-RNHKPMQLSGGQQQRVAIARAMV 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 150 QRPSLMLLDEPFSALDtglraaTRKATADL-----LAEAGVASILVTHDQtEALSFASQVAVMRQGRF 212
Cdd:NF038007 158 SNPALLLADEPTGNLD------SKNARAVLqqlkyINQKGTTIIMVTHSD-EASTYGNRIINMKDGKL 218
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 2-224 1.35e-39

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 146.83  E-value: 1.35e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvFVPAH-QRGI 79
Cdd:COG4988  337 IELEDVSFSYPGGrPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSD---LDPASwRRQI 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGALFpHLNVADNIAWGL-DCSREEKRR--RVAALMEMVA-----LDATLASHwPHEISGGQQQRVALARALAQR 151
Cdd:COG4988  414 AWVPQNPYLF-AGTIRENLRLGRpDASDEELEAalEAAGLDEFVAalpdgLDTPLGEG-GRGLSGGQAQRLALARALLRD 491

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 152 PSLMLLDEPFSALDTGLRAATRKATADLLAEAGVasILVTHDqTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:COG4988  492 APLLLLDEPTAHLDAETEAEILQALRRLAKGRTV--ILITHR-LALLAQADRILVLDDGRIVEQGTHEELLAK 561
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 2-224 1.49e-39

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 140.64  E-value: 1.49e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADA--LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAE---------G 69
Cdd:TIGR04520   1 IEVENVSFSYPESekPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGlDTLDEEnlweirkkvG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   70 -VFV-PAHQrgigFVpqeGALfphlnVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVAL 144
Cdd:TIGR04520  81 mVFQnPDNQ----FV---GAT-----VEDDVAFGLEnlgVPREEMRKRVDEALKLVGMED-FRDREPHLLSGGQKQRVAI 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  145 ARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALsFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:TIGR04520 148 AGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKGKIVAEGTPREIFSQ 226
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 17-225 1.87e-39

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 141.79  E-value: 1.87e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQ-----RGIGFVPQE--GALF 89
Cdd:COG4608   34 VDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITG----LSGRElrplrRRMQMVFQDpyASLN 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHLNVADNIAWGLD----CSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:COG4608  110 PRMTVGDIIAEPLRihglASKAERRERVAELLELVGLRPEHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALD 189

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 166 TGLRAATRKATADLLAEAGVASILVTHDqteaLS----FASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:COG4608  190 VSIQAQVLNLLEDLQDELGLTYLFISHD----LSvvrhISDRVAVMYLGKIVEIAPRDELYARP 249
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 1-225 2.12e-39

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 141.34  E-value: 2.12e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA----DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETP---DNGRIVLQGNTLFA--EGVF 71
Cdd:COG0444    1 LLEVRNLKVYFPtrrgVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKlsEKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  72 VPAHQRGIGFVPQE--GALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALD--ATLASHWPHEISGGQQQRVA 143
Cdd:COG0444   81 RKIRGREIQMIFQDpmTSLNPVMTVGDQIAEPLrihgGLSKAEARERAIELLERVGLPdpERRLDRYPHELSGGMRQRVM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 144 LARALAQRPSLMLLDEPFSALDtglraATRKAT-----ADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTP 218
Cdd:COG0444  161 IARALALEPKLLIADEPTTALD-----VTIQAQilnllKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPV 235


                 ....*..
gi 505180171 219 FEVYSRP 225
Cdd:COG0444  236 EELFENP 242
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 1-211 2.65e-39

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 138.15  E-value: 2.65e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    1 MLELSSISKSF-ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGVFVPAHQRG 78
Cdd:TIGR02673   1 MIEFHNVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGeDVNRLRGRQLPLLRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   79 IGFVPQEGALFPHLNVADNIAWGLDCSREEKR---RRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:TIGR02673  81 IGVVFQDFRLLPDRTVYENVALPLEVRGKKEReiqRRVGAALRQVGL-EHKADAFPEQLSGGEQQRVAIARAIVNSPPLL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171  156 LLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:TIGR02673 160 LADEPTGNLD----PDLSERILDLLKRlnkRGTTVIVATHDLSLVDRVAHRVIILDDGR 214
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
10-218 4.01e-39

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 145.69  E-value: 4.01e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  10 SFA---DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG--------NTLfaegvfvpahQRG 78
Cdd:COG1132  346 SFSypgDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGvdirdltlESL----------RRQ 415

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFpHLNVADNIAWG-LDCSREEKRR--RVAALMEMVA-----LDATLAshwphE----ISGGQQQRVALAR 146
Cdd:COG1132  416 IGVVPQDTFLF-SGTIRENIRYGrPDATDEEVEEaaKAAQAHEFIEalpdgYDTVVG-----ErgvnLSGGQRQRIAIAR 489

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 147 ALAQRPSLMLLDEPFSALDTGLRAATRKATADLLaeAGVASILVTHDqteaLS---FASQVAVMRQGRFAQVGTP 218
Cdd:COG1132  490 ALLKDPPILILDEATSALDTETEALIQEALERLM--KGRTTIVIAHR----LStirNADRILVLDDGRIVEQGTH 558
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 1-236 1.39e-38

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 137.08  E-value: 1.39e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSrtaIV---GPSGSGKTTLLRILAGFETPDNGRIVLQGN--TLFaegvfvPAH 75
Cdd:COG1137    3 TLEAENLVKSYGKRTVVKDVSLEVNQGE---IVgllGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEdiTHL------PMH 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  76 QR---GIGFVPQEGALFPHLNVADNIA-----WGLDcsREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARA 147
Cdd:COG1137   74 KRarlGIGYLPQEASIFRKLTVEDNILavlelRKLS--KKEREERLEELLEEFGI-THLRKSKAYSLSGGERRRVEIARA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 148 LAQRPSLMLLDEPFSALDTglraatrKATADL------LAEAGVaSILVT-HDQTEALSFASQVAVMRQGR-FAQvGTPF 219
Cdd:COG1137  151 LATNPKFILLDEPFAGVDP-------IAVADIqkiirhLKERGI-GVLITdHNVRETLGICDRAYIISEGKvLAE-GTPE 221

                        250
                 ....*....|....*..
gi 505180171 220 EVYSRPvdEATALFLGD 236
Cdd:COG1137  222 EILNNP--LVRKVYLGE 236
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 2-216 1.73e-38

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 136.17  E-value: 1.73e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSrTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHqrgIGF 81
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPGM-YGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRR---IGY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNV---ADNIAWGLDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03264   77 LPQEFGVYPNFTVrefLDYIAWLKGIPSKEVKARVDEVLELVNL-GDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVasILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03264  156 EPTAGLDPEERIRFRNLLSELGEDRIV--ILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 1-235 1.73e-38

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 136.65  E-value: 1.73e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQR--- 77
Cdd:COG0410    3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITG----LPPHRIarl 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIAWGLDCSReeKRRRVAALMEMV------------ALDATLashwpheiSGGQQQRVALA 145
Cdd:COG0410   79 GIGYVPEGRRIFPSLTVEENLLLGAYARR--DRAEVRADLERVyelfprlkerrrQRAGTL--------SGGEQQMLAIG 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 146 RALAQRPSLMLLDEP------------FSALDTglraatrkatadlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFA 213
Cdd:COG0410  149 RALMSRPKLLLLDEPslglapliveeiFEIIRR-------------LNREGVTILLVEQNARFALEIADRAYVLERGRIV 215

                        250       260
                 ....*....|....*....|..
gi 505180171 214 QVGTPFEVYSRPvdEATALFLG 235
Cdd:COG0410  216 LEGTAAELLADP--EVREAYLG 235
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 2-220 1.77e-38

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 136.10  E-value: 1.77e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA--LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVfvpAHQRGI 79
Cdd:cd03263    1 LQIRNLTKTYKKGtkPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRK---AARQSL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGALFPHLNVADNI-----AWGLdcSREEKRRRVAALMEMVAldatLASHW---PHEISGGQQQRVALARALAQR 151
Cdd:cd03263   78 GYCPQFDALFDELTVREHLrfyarLKGL--PKSEIKEEVELLLRVLG----LTDKAnkrARTLSGGMKRKLSLAIALIGG 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 152 PSLMLLDEPFSALDtglrAATRKATADLLAEAGVAS--ILVTHDQTEALSFASQVAVMRQGRFAQVGTPFE 220
Cdd:cd03263  152 PSVLLLDEPTSGLD----PASRRAIWDLILEVRKGRsiILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQE 218
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 2-211 2.00e-38

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 136.00  E-value: 2.00e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSF-ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGVFVPAHQRGI 79
Cdd:cd03292    1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGqDVSDLRGRAIPYLRRKI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGALFPHLNVADNIAWGLDCS---REEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:cd03292   81 GVVFQDFRLLPDRNVYENVAFALEVTgvpPREIRKRVPAALELVGL-SHKHRALPAELSGGEQQRVAIARAIVNSPTILI 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 157 LDEPFSALDTglraATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03292  160 ADEPTGNLDP----DTTWEIMNLLKKinkAGTTVVVATHAKELVDTTRHRVIALERGK 213
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 17-241 5.73e-38

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 141.75  E-value: 5.73e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFEtPDNGRIVLQGNTLFAegvfVPAHQ-----RGIGFVPQE--GALF 89
Cdd:COG4172  302 VDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDG----LSRRAlrplrRRMQVVFQDpfGSLS 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHLNVADNIAWGL-----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:COG4172  377 PRMTVGQIIAEGLrvhgpGLSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSAL 456

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 165 DTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDALVLD 241
Cdd:COG4172  457 DVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 2-226 1.35e-37

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 134.21  E-value: 1.35e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQR---G 78
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITK----LPMHKRarlG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGLDC---SREEKRRRVAALMEMVALDA---TLASHwpheISGGQQQRVALARALAQRP 152
Cdd:cd03218   77 IGYLPQEASIFRKLTVEENILAVLEIrglSKKEREEKLEELLEEFHITHlrkSKASS----LSGGERRRVEIARALATNP 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 153 SLMLLDEPFSALDTglraatrKATADL------LAEAGVaSILVT-HDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:cd03218  153 KFLLLDEPFAGVDP-------IAVQDIqkiikiLKDRGI-GVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANE 224


                 .
gi 505180171 226 V 226
Cdd:cd03218  225 L 225
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
12-224 2.23e-37

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 135.14  E-value: 2.23e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFvpAHQRGIGFVPQE------ 85
Cdd:PRK13635  18 AATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVW--DVRRQVGMVFQNpdnqfv 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  86 GAlfphlNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK13635  96 GA-----TVQDDVAFGLEnigVPREEMVERVDQALRQVGMED-FLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATS 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171 163 ALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSfASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:PRK13635 170 MLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFKS 230
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 2-234 3.97e-37

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 133.60  E-value: 3.97e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGV---FVPAHQR 77
Cdd:PRK11124   3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdFSKTPsdkAIRELRR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNI------AWGLdcSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQR 151
Cdd:PRK11124  83 NVGMVFQQYNLWPHLTVQQNLieapcrVLGL--SKDQALARAEKLLERLRL-KPYADRFPLHLSGGQQQRVAIARALMME 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 152 PSLMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPfEVYSRPVDEATA 231
Cdd:PRK11124 160 PQVLLFDEPTAALDPEITAQIVSIIRE-LAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDA-SCFTQPQTEAFK 237


                 ...
gi 505180171 232 LFL 234
Cdd:PRK11124 238 NYL 240
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 2-211 4.50e-37

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 132.40  E-value: 4.50e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegvfVPAHQRGIGF 81
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPL------DIAARNRIGY 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAW-----GLdcSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:cd03269   75 LPEERGLYPKMKVIDQLVYlaqlkGL--KKEEARRRIDEWLERLEL-SEYANKRVEELSKGNQQKVQFIAAVIHDPELLI 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 157 LDEPFSALDTgLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03269  152 LDEPFSGLDP-VNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGR 205
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 12-277 4.96e-37

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 135.48  E-value: 4.96e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALV--LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGVFVPAHQRGIGFVPQE--G 86
Cdd:PRK11308  24 PERLVkaLDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGqDLLKADPEAQKLLRQKIQIVFQNpyG 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  87 ALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK11308 104 SLNPRKKVGQILEEPLlintSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVS 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 163 ALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDALVLDA 242
Cdd:PRK11308 184 ALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPRHPYTQALLSATPRLNP 263

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 505180171 243 ELMEGRARCAiGELP------------TDDPHANGRGRVmLRPeQLR 277
Cdd:PRK11308 264 DDRRERIKLT-GELPsplnpppgcafnARCPRAFGRCRQ-EQP-QLR 307
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 1-222 1.03e-36

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 132.42  E-value: 1.03e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    1 MLELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGVFVPAHQRG 78
Cdd:TIGR02315   1 MLEVENLSKVYPNGkQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDItKLRGKKLRKLRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   79 IGFVPQEGALFPHLNVADNI-------------AWGLdCSREEKRRRVAALmEMVALDAtLASHWPHEISGGQQQRVALA 145
Cdd:TIGR02315  81 IGMIFQHYNLIERLTVLENVlhgrlgykptwrsLLGR-FSEEDKERALSAL-ERVGLAD-KAYQRADQLSGGQQQRVAIA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171  146 RALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVY 222
Cdd:TIGR02315 158 RALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELD 234
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
16-232 1.05e-36

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 133.27  E-value: 1.05e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA-EGVFVPAHQRGIGFVPQE--GALFPHL 92
Cdd:PRK10419  27 VLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKlNRAQRKAFRRDIQMVFQDsiSAVNPRK 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 NVADNIAWGL----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL 168
Cdd:PRK10419 107 TVREIIREPLrhllSLDKAERLARASEMLRAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVL 186

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 169 RAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFaqvgtpfeVYSRPVDEATAL 232
Cdd:PRK10419 187 QAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQI--------VETQPVGDKLTF 242
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-221 2.98e-36

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 131.36  E-value: 2.98e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETP-DNGRIVLQGNTLFAEGVFvpAHQRGI 79
Cdd:COG1119    3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPtYGNDVRLFGERRGGEDVW--ELRKRI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGALF--PHLNVADNIAWGLDCS-------REEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQ 150
Cdd:COG1119   81 GLVSPALQLRfpRDETVLDVVLSGFFDSiglyrepTDEQRERARELLELLGLAH-LADRPFGTLSQGEQRRVLIARALVK 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 151 RPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:COG1119  160 DPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEV 230
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 2-234 4.82e-36

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 130.88  E-value: 4.82e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRIL-------AGFETpdNGRIVLQGNTLFAEGVFVPA 74
Cdd:TIGR00972   2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLnrmndlvPGVRI--EGKVLFDGQDIYDKKIDVVE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   75 HQRGIGFVPQEGALFPhLNVADNIAWGLDC----SREEKRRRVAALMEMVAL-DA--TLASHWPHEISGGQQQRVALARA 147
Cdd:TIGR00972  80 LRRRVGMVFQKPNPFP-MSIYDNIAYGPRLhgikDKKELDEIVEESLKKAALwDEvkDRLHDSALGLSGGQQQRLCIARA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  148 LAQRPSLMLLDEPFSALDTglrAATRK--ATADLLAEAgVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:TIGR00972 159 LAVEPEVLLLDEPTSALDP---IATGKieELIQELKKK-YTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNP 234


                  ....*....
gi 505180171  226 VDEATALFL 234
Cdd:TIGR00972 235 KEKRTEDYI 243
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 15-235 5.91e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 131.68  E-value: 5.91e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  15 LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqGNTLFAEGV----FVPAHQR-GIGFVPQEGALF 89
Cdd:PRK13634  21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GERVITAGKknkkLKPLRKKvGIVFQFPEHQLF 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHlNVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:PRK13634 100 EE-TVEKDICFGpmnFGVSEEDAKQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDP 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 167 GLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPvDEATALFLG 235
Cdd:PRK13634 179 KGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP-DELEAIGLD 246
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 2-220 6.23e-36

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 129.80  E-value: 6.23e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVpahQRGIGF 81
Cdd:cd03265    1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREV---RRRIGI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAW-----GLdcSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:cd03265   78 VFQDLSVDDELTGWENLYIharlyGV--PGAERRERIDELLDFVGL-LEAADRLVKTYSGGMRRRLEIARSLVHRPEVLF 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 157 LDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFE 220
Cdd:cd03265  155 LDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEE 218
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 2-211 9.01e-36

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 127.72  E-value: 9.01e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA--LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfvPAHQRG- 78
Cdd:cd03246    1 LEVENVSFRYPGAepPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWD---PNELGDh 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHlNVADNIawgldcsreekrrrvaalmemvaldatlashwpheISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03246   78 VGYLPQDDELFSG-SIAENI-----------------------------------LSGGQRQRLGLARALYGNPRILVLD 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 505180171 159 EPFSALDTGLRAATRKATADLLAeAGVASILVTHdQTEALSFASQVAVMRQGR 211
Cdd:cd03246  122 EPNSHLDVEGERALNQAIAALKA-AGATRIVIAH-RPETLASADRILVLEDGR 172
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 12-225 1.42e-35

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 135.66  E-value: 1.42e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvFVPAHQRG-IGFVPQEGALFp 90
Cdd:COG4987  346 AGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRD---LDEDDLRRrIAVVPQRPHLF- 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  91 HLNVADNIAWGL-DCSREEkrrrVAALMEMVALDATLASH------WPHE----ISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:COG4987  422 DTTLRENLRLARpDATDEE----LWAALERVGLGDWLAALpdgldtWLGEggrrLSGGERRRLALARALLRDAPILLLDE 497

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 160 PFSALDtglrAATRKATADLLAEA--GVASILVTHDQTeALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:COG4987  498 PTEGLD----AATEQALLADLLEAlaGRTVLLITHRLA-GLERMDRILVLEDGRIVEQGTHEELLAQN 560
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 2-211 1.42e-35

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 128.86  E-value: 1.42e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA--LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfaegvfVPAHQ--- 76
Cdd:cd03245    3 IEFRNVSFSYPNQeiPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDG---------TDIRQldp 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 ----RGIGFVPQEGALFpHLNVADNIAWGLDCSREEkrrRVAALMEMVALDATLASHwPH-----------EISGGQQQR 141
Cdd:cd03245   74 adlrRNIGYVPQDVTLF-YGTLRDNITLGAPLADDE---RILRAAELAGVTDFVNKH-PNgldlqigergrGLSGGQRQA 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 142 VALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVasILVTHdQTEALSFASQVAVMRQGR 211
Cdd:cd03245  149 VALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTL--IIITH-RPSLLDLVDRIIVMDSGR 215
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 1-211 1.74e-35

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 129.93  E-value: 1.74e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    1 MLELSSISKSFADAL---------VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA-EGV 70
Cdd:TIGR02769   2 LLEVRDVTHTYRTGGlfgakqrapVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQlDRK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   71 FVPAHQRGIGFVPQE--GALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVAL 144
Cdd:TIGR02769  82 QRRAFRRDVQLVFQDspSAVNPRMTVRQIIGEPLrhltSLDESEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQRINI 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171  145 ARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:TIGR02769 162 ARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQ 228
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 2-217 1.83e-35

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 126.39  E-value: 1.83e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEgvfvP--AHQRG 78
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVsFAS----PrdARRAG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQegalfphlnvadniawgldcsreekrrrvaalmemvaldatlashwpheISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03216   77 IAMVYQ-------------------------------------------------LSVGERQMVEIARALARNARLLILD 107

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 159 EPFSALdtglraaTRKATADL------LAEAGVASILVTHDQTEALSFASQVAVMRQGRfaQVGT 217
Cdd:cd03216  108 EPTAAL-------TPAEVERLfkvirrLRAQGVAVIFISHRLDEVFEIADRVTVLRDGR--VVGT 163
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 16-224 2.05e-35

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 128.89  E-value: 2.05e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFpHLNVA 95
Cdd:cd03253   16 VLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDI--REVTLDSLRRAIGVVPQDTVLF-NDTIG 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWG-LDCSREEKRR--RVAAL----MEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL 168
Cdd:cd03253   93 YNIRYGrPDATDEEVIEaaKAAQIhdkiMRFPDGYDTIVGERGLKLSGGEKQRVAIARAILKNPPILLLDEATSALDTHT 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 169 RAATRKATADLLaeAGVASILVTHDQTEALSfASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:cd03253  173 EREIQAALRDVS--KGRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEELLAK 225
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 2-217 9.16e-35

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 126.87  E-value: 9.16e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQR---G 78
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITK----LPPHERaraG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   79 IGFVPQEGALFPHLNVADNIAWGLDCSREEKRRRVA-------ALMEMVALDATLashwpheISGGQQQRVALARALAQR 151
Cdd:TIGR03410  77 IAYVPQGREIFPRLTVEENLLTGLAALPRRSRKIPDeiyelfpVLKEMLGRRGGD-------LSGGQQQQLAIARALVTR 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171  152 PSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGT 217
Cdd:TIGR03410 150 PKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGA 215
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 11-231 1.23e-34

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 127.08  E-value: 1.23e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  11 FADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRIL-------AGFETpdNGRIVLQGNTLFAEGVFVPAHQRGIGFVP 83
Cdd:COG1117   21 YGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmndliPGARV--EGEILLDGEDIYDPDVDVVELRRRVGMVF 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  84 QEGALFPHlNVADNIAWGL----DCSREEKRRRV------AALMEMVA--LD--ATlashwphEISGGQQQRVALARALA 149
Cdd:COG1117   99 QKPNPFPK-SIYDNVAYGLrlhgIKSKSELDEIVeeslrkAALWDEVKdrLKksAL-------GLSGGQQQRLCIARALA 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 150 QRPSLMLLDEPFSALDTglraatrKATA---DLLAEAG--VASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:COG1117  171 VEPEVLLMDEPTSALDP-------ISTAkieELILELKkdYTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTN 243


                 ....*..
gi 505180171 225 PVDEATA 231
Cdd:COG1117  244 PKDKRTE 250
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-225 3.16e-34

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 126.42  E-value: 3.16e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfVPAHQRG-- 78
Cdd:PRK11831   7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGEN-------IPAMSRSrl 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 ------IGFVPQEGALFPHLNVADNIAWGLdcsREEKRR-----RVAALMEMVALDATLASH-WPHEISGGQQQRVALAR 146
Cdd:PRK11831  80 ytvrkrMSMLFQSGALFTDMNVFDNVAYPL---REHTQLpapllHSTVMMKLEAVGLRGAAKlMPSELSGGMARRAALAR 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 147 ALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK11831 157 AIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANP 235
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-279 1.08e-33

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 130.19  E-value: 1.08e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKT----TLLRILAGFETPDNGRIVLQGNTLFAegvfV 72
Cdd:COG4172    6 LLSVEDLSVAFGQGggtvEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLG----L 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  73 PAHQ----RG--IGFVPQE--GALFPHLNVADNIAWGLDC----SREEKRRRVAALMEMVALD--ATLASHWPHEISGGQ 138
Cdd:COG4172   82 SERElrriRGnrIAMIFQEpmTSLNPLHTIGKQIAEVLRLhrglSGAAARARALELLERVGIPdpERRLDAYPHQLSGGQ 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 139 QQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTP 218
Cdd:COG4172  162 RQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPT 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171 219 FEVYSRPVDEAT-ALflgdalvLDAElMEGRARcaigELPTDDPhangrgrVMLRPEQLRVS 279
Cdd:COG4172  242 AELFAAPQHPYTrKL-------LAAE-PRGDPR----PVPPDAP-------PLLEARDLKVW 284
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 4-193 1.09e-33

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 129.80  E-value: 1.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   4 LSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfvpahqRgIGFVP 83
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGL------------R-IGYLP 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  84 QEGALFPHLNVADNIAWGLDCSREEKRRRVAALMEMVALDATLA------------------------------SHWPH- 132
Cdd:COG0488   68 QEPPLDDDLTVLDTVLDGDAELRALEAELEELEAKLAEPDEDLErlaelqeefealggweaearaeeilsglgfPEEDLd 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 133 ----EISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrAATRKATADLLAEAGVASILVTHD 193
Cdd:COG0488  148 rpvsELSGGWRRRVALARALLSEPDLLLLDEPTNHLD----LESIEWLEEFLKNYPGTVLVVSHD 208
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
2-230 1.32e-33

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 124.95  E-value: 1.32e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADAL---------VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGVF 71
Cdd:COG4167    5 LEVRNLSKTFKYRTglfrrqqfeAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLeYGDYKY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  72 VPAHQRGIgFVPQEGALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARA 147
Cdd:COG4167   85 RCKHIRMI-FQDPNTSLNPRLNIGQILEEPLrlntDLTAEEREERIFATLRLVGLLPEHANFYPHMLSSGQKQRVALARA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 148 LAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVD 227
Cdd:COG4167  164 LILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFANPQH 243


                 ...
gi 505180171 228 EAT 230
Cdd:COG4167  244 EVT 246
cbiO PRK13637
energy-coupling factor transporter ATPase;
17-222 2.75e-33

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 124.39  E-value: 2.75e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIGFVPQ--EGALFPHlNV 94
Cdd:PRK13637  23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLSDIRKKVGLVFQypEYQLFEE-TI 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  95 ADNIAWG---LDCSREEKRRRVAALMEMVALD-ATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:PRK13637 102 EKDIAFGpinLGLSEEEIENRVKRAMNIVGLDyEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRD 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 505180171 171 ATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVY 222
Cdd:PRK13637 182 EILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
14-234 3.40e-33

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 126.69  E-value: 3.40e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  14 ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL--FAEGVFVPAHQRGIGFVPQEGALFPH 91
Cdd:PRK10070  41 SLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIakISDAELREVRRKKIAMVFQSFALMPH 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 LNVADNIAWGLDCS---REEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL 168
Cdd:PRK10070 121 MTVLDNTAFGMELAginAEERREKALDALRQVGLE-NYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLI 199

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 169 RAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFL 234
Cdd:PRK10070 200 RTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFF 265
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 3-210 3.56e-33

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 121.98  E-value: 3.56e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgvfvpAHQRGIGF 81
Cdd:cd03226    1 RIENISFSYKKGtEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAK-----ERRKSIGY 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQE--GALFPHlNVADNIAWGLDCSrEEKRRRVAALMEMVALDATLASHwPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:cd03226   76 VMQDvdYQLFTD-SVREELLLGLKEL-DAGNEQAETVLKDLDLYALKERH-PLSLSGGQKQRLAIAAALLSGKDLLIFDE 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 505180171 160 PFSALDtglrAATRKATADL---LAEAGVASILVTHDQTEALSFASQVAVMRQG 210
Cdd:cd03226  153 PTSGLD----YKNMERVGELireLAAQGKAVIVITHDYEFLAKVCDRVLLLANG 202
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 1-193 1.28e-32

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 127.10  E-value: 1.28e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqGNTLFaegvfvpahqrgIG 80
Cdd:COG0488  315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETVK------------IG 381

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALF-PHLNVADNIAWGLDCSREEKRRRVAALM----EMV-----ALdatlashwpheiSGGQQQRVALARALAQ 150
Cdd:COG0488  382 YFDQHQEELdPDKTVLDELRDGAPGGTEQEVRGYLGRFlfsgDDAfkpvgVL------------SGGEKARLALAKLLLS 449

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 505180171 151 RPSLMLLDEPFSALDTglraATRKATADLLAE-AGVAsILVTHD 193
Cdd:COG0488  450 PPNVLLLDEPTNHLDI----ETLEALEEALDDfPGTV-LLVSHD 488
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 12-224 4.94e-32

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 125.63  E-value: 4.94e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA--EGVFvpahQRGIGFVPQEGALF 89
Cdd:COG4618  343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQwdREEL----GRHIGYLPQDVELF 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHlNVADNIAWGLDCSREE--KRRRVAALMEMVA---------LDATLAShwpheISGGQQQRVALARALAQRPSLMLLD 158
Cdd:COG4618  419 DG-TIAENIARFGDADPEKvvAAAKLAGVHEMILrlpdgydtrIGEGGAR-----LSGGQRQRIGLARALYGDPRLVVLD 492

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 159 EPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTeALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:COG4618  493 EPNSNLDDEGEAALAAAIRA-LKARGATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDEVLAR 556
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 2-193 7.51e-32

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 125.09  E-value: 7.51e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvFVPAH-QRGI 79
Cdd:TIGR02857 322 LEFSGVSVAYPGRrPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLAD---ADADSwRDQI 398

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   80 GFVPQEGALFPHlNVADNIAWGL-DCSREEKRR--RVAALMEMVA-----LDATLASHwPHEISGGQQQRVALARALAQR 151
Cdd:TIGR02857 399 AWVPQHPFLFAG-TIAENIRLARpDASDAEIREalERAGLDEFVAalpqgLDTPIGEG-GAGLSGGQAQRLALARAFLRD 476

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 505180171  152 PSLMLLDEPFSALDTGLRAATRKATADLLaeAGVASILVTHD 193
Cdd:TIGR02857 477 APLLLLDEPTAHLDAETEAEVLEALRALA--QGRTVLLVTHR 516
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
16-214 1.10e-31

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 118.76  E-value: 1.10e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL--FAEGVFVPAHQRGIGFVPQEGALFPHLN 93
Cdd:PRK11629  24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMskLSSAAKAELRNQKLGFIYQFHHLLPDFT 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIAWGL---DCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrA 170
Cdd:PRK11629 104 ALENVAMPLligKKKPAEINSRALEMLAAVGLEHR-ANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLD----A 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 505180171 171 ATRKATADLLAE----AGVASILVTHDQTEALSFASQVAvMRQGRFAQ 214
Cdd:PRK11629 179 RNADSIFQLLGElnrlQGTAFLVVTHDLQLAKRMSRQLE-MRDGRLTA 225
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 13-224 2.40e-31

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 118.03  E-value: 2.40e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  13 DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFPhL 92
Cdd:cd03249   15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDI--RDLNLRWLRSQIGLVSQEPVLFD-G 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 NVADNIAWGLDCSREEKRRRVAALmemVALDATLAShWPH-----------EISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03249   92 TIAENIRYGKPDATDEEVEEAAKK---ANIHDFIMS-LPDgydtlvgergsQLSGGQKQRIAIARALLRNPKILLLDEAT 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 162 SALDTglraATRKATADLLAEA--GVASILVTHDQTeALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:cd03249  168 SALDA----ESEKLVQEALDRAmkGRTTIVIAHRLS-TIRNADLIAVLQNGQVVEQGTHDELMAQ 227
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 12-211 2.76e-31

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 124.21  E-value: 2.76e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfaegvfVPAHQ-------RGIGFVPQ 84
Cdd:TIGR03375 476 QETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDG---------VDIRQidpadlrRNIGYVPQ 546

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   85 EGALFpHLNVADNIAWGLDCSREEKRRRVAalmEMVALDATLASHwPH-----------EISGGQQQRVALARALAQRPS 153
Cdd:TIGR03375 547 DPRLF-YGTLRDNIALGAPYADDEEILRAA---ELAGVTEFVRRH-PDgldmqigergrSLSGGQRQAVALARALLRDPP 621

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171  154 LMLLDEPFSALDTGLRAATRKATADLLAEAGVasILVTHdQTEALSFASQVAVMRQGR 211
Cdd:TIGR03375 622 ILLLDEPTSAMDNRSEERFKDRLKRWLAGKTL--VLVTH-RTSLLDLVDRIIVMDNGR 676
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 1-216 2.94e-31

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 117.08  E-value: 2.94e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA----LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVpahQ 76
Cdd:cd03266    1 MITADALTKRFRDVkktvQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEA---R 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPHLNVADNIAW-----GLDCSREEKR-RRVAALMEMVALDATLAShwphEISGGQQQRVALARALAQ 150
Cdd:cd03266   78 RRLGFVSDSTGLYDRLTARENLEYfaglyGLKGDELTARlEELADRLGMEELLDRRVG----GFSTGMRQKVAIARALVH 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 151 RPSLMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03266  154 DPPVLLLDEPTTGLDVMATRALREFIRQ-LRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 8-211 3.83e-31

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 116.41  E-value: 3.83e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   8 SKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGfETPdngriVLQGNtlfaegVFVPahqRGIGFVPQEGA 87
Cdd:cd03250   12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLG-ELE-----KLSGS------VSVP---GSIAYVSQEPW 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  88 LfphLN--VADNIAWG--LDcsrEEKRRRVaalMEMVALDATLAShWPH----EI-------SGGQQQRVALARALAQRP 152
Cdd:cd03250   77 I---QNgtIRENILFGkpFD---EERYEKV---IKACALEPDLEI-LPDgdltEIgekginlSGGQKQRISLARAVYSDA 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 153 SLMLLDEPFSALD--TGlRAATRKATADLLAEaGVASILVTHdQTEALSFASQVAVMRQGR 211
Cdd:cd03250  147 DIYLLDDPLSAVDahVG-RHIFENCILGLLLN-NKTRILVTH-QLQLLPHADQIVVLDNGR 204
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
2-238 4.42e-31

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 117.76  E-value: 4.42e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLF----AEGVFVPAHQR 77
Cdd:PRK10619   6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdKDGQLKVADKN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GI-------GFVPQEGALFPHLNVADNIAWG----LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALAR 146
Cdd:PRK10619  86 QLrllrtrlTMVFQHFNLWSHMTVLENVMEApiqvLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIAR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 147 ALAQRPSLMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPV 226
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDPELVGEVLRIMQQ-LAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQ 244

                        250
                 ....*....|..
gi 505180171 227 DEATALFLGDAL 238
Cdd:PRK10619 245 SPRLQQFLKGSL 256
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
10-199 4.50e-31

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 115.79  E-value: 4.50e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  10 SFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaegvfvpahqRGIGFVPQEGAL- 88
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG-------------ARVAYVPQRSEVp 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  89 --FPhLNVADNIAWG-------LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:NF040873  68 dsLP-LTVRDLVAMGrwarrglWRRLTRDDRAAVDDALERVGL-ADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDE 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 505180171 160 PFSALDtglrAATRKATADLLAEA---GVASILVTHDQTEALS 199
Cdd:NF040873 146 PTTGLD----AESRERIIALLAEEharGATVVVVTHDLELVRR 184
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 16-221 5.27e-31

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 116.94  E-value: 5.27e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFPHlNVA 95
Cdd:cd03254   18 VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDI--RDISRKSLRSMIGVVLQDTFLFSG-TIM 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWGLDCSREEkrrRVAALMEMVALD----------ATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:cd03254   95 ENIRLGRPNATDE---EVIEAAKEAGAHdfimklpngyDTVLGENGGNLSQGERQLLAIARAMLRDPKILILDEATSNID 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 166 TGLRAATRKATADLLaeAGVASILVTHdqteALS---FASQVAVMRQGRFAQVGTPFEV 221
Cdd:cd03254  172 TETEKLIQEALEKLM--KGRTSIIIAH----RLStikNADKILVLDDGKIIEEGTHDEL 224
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 2-240 7.99e-31

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 116.92  E-value: 7.99e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAHQR---G 78
Cdd:PRK10895   4 LTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDI----SLLPLHARarrG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:PRK10895  80 IGYLPQEASIFRRLSVYDNLMAVLqirdDLSAEQREDRANELMEEFHI-EHLRDSMGQSLSGGERRRVEIARALAANPKF 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 155 MLLDEPFSALDTgLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRpvDEATALFL 234
Cdd:PRK10895 159 ILLDEPFAGVDP-ISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQD--EHVKRVYL 235


                 ....*.
gi 505180171 235 GDALVL 240
Cdd:PRK10895 236 GEDFRL 241
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 14-224 2.35e-30

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 115.28  E-value: 2.35e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  14 ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaeGVFVPAH-QRGIGFVPQEGALFpHL 92
Cdd:cd03252   15 PVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDL---ALADPAWlRRQVGVVLQENVLF-NR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 NVADNIAW---GLDCSREEKRRRVAA----LMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:cd03252   91 SIRDNIALadpGMSMERVIEAAKLAGahdfISELPEGYDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATSALD 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 166 TGLRAATRKATADLLaeAGVASILVTHdQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:cd03252  171 YESEHAIMRNMHDIC--AGRTVIIIAH-RLSTVKNADRIIVMEKGRIVEQGSHDELLAE 226
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 13-234 3.95e-30

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 115.53  E-value: 3.95e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  13 DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGVF---VPAHQRGIGFVPQEGAL 88
Cdd:PRK14246  22 DKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyFGKDIFqidAIKLRKEVGMVFQQPNP 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  89 FPHLNVADNIAWGLDCSREEKRRRVAALMEMVALDATLashWPH----------EISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK14246 102 FPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGL---WKEvydrlnspasQLSGGQQQRLTIARALALKPKVLLMD 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEagVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFL 234
Cdd:PRK14246 179 EPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYV 252
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 1-216 5.14e-30

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 119.77  E-value: 5.14e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtLFAEGVFVPAHQRGIG 80
Cdd:PRK15439  11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGN-PCARLTPAKAHQLGIY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDCSREEKRRrvaalmeMVALDATLASHWPHEISGG-----QQQRVALARALAQRPSLM 155
Cdd:PRK15439  90 LVPQEPLLFPNLSVKENILFGLPKRQASMQK-------MKQLLAALGCQLDLDSSAGslevaDRQIVEILRGLMRDSRIL 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 156 LLDEPFSALDTGLRAATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:PRK15439 163 ILDEPTASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIALSG 222
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 1-221 6.20e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 115.09  E-value: 6.20e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADA--LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFvpaHQRG 78
Cdd:PRK13632   7 MIKVENVSFSYPNSenNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLK---EIRK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 -IGFVPQE-GALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDATLaSHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK13632  84 kIGIIFQNpDNQFIGATVEDDIAFGLEnkkVPPKKMKDIIDDLAKKVGMEDYL-DKEPQNLSGGQKQRVAIASVLALNPE 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSfASQVAVMRQGRFAQVGTPFEV 221
Cdd:PRK13632 163 IIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAIL-ADKVIVFSEGKLIAQGKPKEI 229
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
1-245 6.40e-30

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 114.73  E-value: 6.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAhqRGIG 80
Cdd:PRK11231   2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLA--RRLA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQ-----EGALF---------PHLNVadniaWGldcsR--EEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVAL 144
Cdd:PRK11231  80 LLPQhhltpEGITVrelvaygrsPWLSL-----WG----RlsAEDNARVNQAMEQTRIN-HLADRRLTDLSGGQRQRAFL 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 145 ARALAQRPSLMLLDEPFSALDTG----LRAATRKatadlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFE 220
Cdd:PRK11231 150 AMVLAQDTPVVLLDEPTTYLDINhqveLMRLMRE-----LNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEE 224

                        250       260
                 ....*....|....*....|....*
gi 505180171 221 VYsrpvdeaTALFLGDALVLDAELM 245
Cdd:PRK11231 225 VM-------TPGLLRTVFDVEAEIH 242
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 1-225 1.00e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 114.79  E-value: 1.00e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFAD-ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGVFVPAHQR- 77
Cdd:PRK13639   1 ILETRDLKYSYPDgTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIkYDKKSLLEVRKTv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALF-PhlNVADNIAWG---LDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK13639  81 GIVFQNPDDQLFaP--TVEEDVAFGplnLGLSKEEVEKRVKEALKAVGMEG-FENKPPHHLSGGQKKRVAIAGILAMKPE 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK13639 158 IIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228
cbiO PRK13650
energy-coupling factor transporter ATPase;
17-224 1.11e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 114.83  E-value: 1.11e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQrgIGFVPQE------GAlfp 90
Cdd:PRK13650  23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIRHK--IGMVFQNpdnqfvGA--- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  91 hlNVADNIAWGLD---CSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:PRK13650  98 --TVEDDVAFGLEnkgIPHEEMKERVNEALELVGMQD-FKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPE 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 168 LRAATRKATADLLAEAGVASILVTHDQTE-ALSfaSQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:PRK13650 175 GRLELIKTIKGIRDDYQMTVISITHDLDEvALS--DRVLVMKNGQVESTSTPRELFSR 230
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 1-193 1.29e-29

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 113.30  E-value: 1.29e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA----DAL---VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQgntlFAEGVF-- 71
Cdd:COG4778    4 LLEVENLSKTFTlhlqGGKrlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVR----HDGGWVdl 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  72 --VPAHQ------RGIGFVPQegalfpHLNV-----ADNI------AWGLDcsREEKRRRVAALMEMVALDATLASHWPH 132
Cdd:COG4778   80 aqASPREilalrrRTIGYVSQ------FLRViprvsALDVvaepllERGVD--REEARARARELLARLNLPERLWDLPPA 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 133 EISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrAATRKATADLLAEA---GVASILVTHD 193
Cdd:COG4778  152 TFSGGEQQRVNIARGFIADPPLLLLDEPTASLD----AANRAVVVELIEEAkarGTAIIGIFHD 211
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 2-230 1.34e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 113.85  E-value: 1.34e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDNGRIVLQGNTLFAEGVFvpAHQ 76
Cdd:PRK14247   4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKMDVI--ELR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPHLNVADNIAWGLDC-----SREEKRRRV------AALMEMVA--LDATLAShwpheISGGQQQRVA 143
Cdd:PRK14247  82 RRVQMVFQIPNPIPNLSIFENVALGLKLnrlvkSKKELQERVrwalekAQLWDEVKdrLDAPAGK-----LSGGQQQRLC 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 144 LARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVasILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:PRK14247 157 IARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTI--VLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFT 234


                 ....*..
gi 505180171 224 RPVDEAT 230
Cdd:PRK14247 235 NPRHELT 241
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 16-224 2.11e-29

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 112.71  E-value: 2.11e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFpHLNVA 95
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDV--RDYTLASLRRQIGLVSQDVFLF-NDTVA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWG-LDCSREEKRR--RVAALMEMV-----ALDATLASHWPhEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:cd03251   94 ENIAYGrPGATREEVEEaaRAANAHEFImelpeGYDTVIGERGV-KLSGGQRQRIAIARALLKDPPILILDEATSALDTE 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 168 LRAATRKATADLLaeAGVASILVTHdqteALSF---ASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:cd03251  173 SERLVQAALERLM--KNRTTFVIAH----RLSTienADRIVVLEDGKIVERGTHEELLAQ 226
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 14-223 2.66e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 113.31  E-value: 2.66e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  14 ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIGFVPQEGAlFPHLN 93
Cdd:PRK13648  22 SFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHIGIVFQNPDNQ-FVGSI 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIAWGLD---CSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:PRK13648 101 VKYDVAFGLEnhaVPYDEMHRRVSEALKQVDMLER-ADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQ 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 505180171 171 ATRKATADLLAEAGVASILVTHDQTEALSfASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:PRK13648 180 NLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFD 231
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 18-225 3.63e-29

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 114.42  E-value: 3.63e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  18 DNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEG-VFVPAHQRGIGFVPQE--GALFPHLNV 94
Cdd:PRK15079  38 DGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKdDEWRAVRSDIQMIFQDplASLNPRMTI 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  95 ADNIAWGL-----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLR 169
Cdd:PRK15079 118 GEIIAEPLrtyhpKLSRQEVKDRVKAMMLKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQ 197

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 170 AATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK15079 198 AQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNP 253
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 17-223 4.31e-29

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 117.21  E-value: 4.31e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI-VLQGNTlfaegvFVPAHQRG----------IGFVPQE 85
Cdd:TIGR03269 300 VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnVRVGDE------WVDMTKPGpdgrgrakryIGILHQE 373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   86 GALFPHLNVADNI--AWGLDCSREEKRRRVAALMEMVALDATLASH----WPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:TIGR03269 374 YDLYPHRTVLDNLteAIGLELPDELARMKAVITLKMVGFDEEKAEEildkYPDELSEGERHRVALAQVLIKEPRIVILDE 453

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171  160 PFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:TIGR03269 454 PTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIVE 517
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 16-230 5.00e-29

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 117.11  E-value: 5.00e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTT----LLRILAGfetpdNGRIVLQGNTL--FAEGVFVPAHQRgIGFVPQE--GA 87
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLhnLNRRQLLPVRHR-IQVVFQDpnSS 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  88 LFPHLNVADNIAWGL-----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK15134 375 LNPRLNVLQIIEEGLrvhqpTLSAAQREQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTS 454

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 163 ALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEAT 230
Cdd:PRK15134 455 SLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYT 522
cbiO PRK13640
energy-coupling factor transporter ATPase;
16-226 1.18e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 112.20  E-value: 1.18e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPD---NGRIVLQGNTLFAEGVFVPAHQRGIGFVPQEGAlFPHL 92
Cdd:PRK13640  22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDdnpNSKITVDGITLTAKTVWDIREKVGIVFQNPDNQ-FVGA 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 NVADNIAWGLD---CSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLR 169
Cdd:PRK13640 101 TVGDDVAFGLEnraVPRPEMIKIVRDVLADVGM-LDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGK 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 170 AATRKATADLLAEAGVASILVTHDQTEAlSFASQVAVMRQGRFAQVGTPFEVYSRPV 226
Cdd:PRK13640 180 EQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKVE 235
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 13-225 2.00e-28

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 115.97  E-value: 2.00e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   13 DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfaegvfVPAHQ-------RGIGFVPQE 85
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDG---------VPLVQydhhylhRQVALVGQE 563

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   86 GALFPHlNVADNIAWGLDCSREEKRRRVAAL-------MEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR00958 564 PVLFSG-SVRENIAYGLTDTPDEEIMAAAKAanahdfiMEFPNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILD 642

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171  159 EPFSALDtglrAATRKATADLLAEAGVASILVTHdQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:TIGR00958 643 EATSALD----AECEQLLQESRSRASRTVLLIAH-RLSTVERADQILVLKKGSVVEMGTHKQLMEDQ 704
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 2-211 3.11e-28

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 108.84  E-value: 3.11e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgvfVPAHQRgIGF 81
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKN---IEALRR-IGA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQEGALFPHLNVADNIAWgLDCSREEKRRRVAALMEMVALDATlashwPHE----ISGGQQQRVALARALAQRPSLMLL 157
Cdd:cd03268   77 LIEAPGFYPNLTARENLRL-LARLLGIRKKRIDEVLDVVGLKDS-----AKKkvkgFSLGMKQRLGIALALLGNPDLLIL 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 505180171 158 DEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03268  151 DEPTNGLDPDGIKELRELILS-LRDQGITVLISSHLLSEIQKVADRIGIINKGK 203
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 14-212 3.85e-28

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 107.90  E-value: 3.85e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  14 ALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfAEGVFVPAHQRGIGFVP---QEGALFP 90
Cdd:cd03215   13 KGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPV-TRRSPRDAIRAGIAYVPedrKREGLVL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  91 HLNVADNIAwgldcsreekrrrvaalmemvaldatLASHwpheISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:cd03215   92 DLSVAENIA--------------------------LSSL----LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKA 141

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 505180171 171 ATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRF 212
Cdd:cd03215  142 EIYRLIRE-LADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
cbiO PRK13649
energy-coupling factor transporter ATPase;
17-224 4.96e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 110.22  E-value: 4.96e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQ--RGIGFVPQ--EGALFPHl 92
Cdd:PRK13649  23 LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQirKKVGLVFQfpESQLFEE- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 NVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglr 169
Cdd:PRK13649 102 TVLKDVAFGpqnFGVSQEEAEALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLD---- 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 170 AATRKATADL---LAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:PRK13649 178 PKGRKELMTLfkkLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-221 5.64e-28

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 110.67  E-value: 5.64e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfVPAHQR---- 77
Cdd:PRK13537   8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEP-------VPSRARharq 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIA-----WGLdcSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRP 152
Cdd:PRK13537  81 RVGVVPQFDNLDPDFTVRENLLvfgryFGL--SAAAARALVPPLLEFAKLENK-ADAKVGELSGGMKRRLTLARALVNDP 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 153 SLMLLDEPFSALDTGLRAATRKATADLLAeAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:PRK13537 158 DVLVLDEPTTGLDPQARHLMWERLRSLLA-RGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHAL 225
GguA NF040905
sugar ABC transporter ATP-binding protein;
1-211 1.29e-27

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 112.58  E-value: 1.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAG------FEtpdnGRIVLQGNTL-F-----AE 68
Cdd:NF040905   1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGEVCrFkdirdSE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  69 gvfvpahQRGIGFVPQEGALFPHLNVADNIAWGLDCSR------EEKRRRVAALMEMVALD---ATLASHwpheISGGQQ 139
Cdd:NF040905  77 -------ALGIVIIHQELALIPYLSIAENIFLGNERAKrgvidwNETNRRARELLAKVGLDespDTLVTD----IGVGKQ 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 140 QRVALARALAQRPSLMLLDEPFSALDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:NF040905 146 QLVEIAKALSKDVKLLILDEPTAALN----EEDSAALLDLLLElkaQGITSIIISHKLNEIRRVADSITVLRDGR 216
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 1-296 1.83e-27

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 112.33  E-value: 1.83e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAG---FETPDnGRIVLQGNTLFAEGVfVPAHQR 77
Cdd:PRK13549   5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGvypHGTYE-GEIIFEGEELQASNI-RDTERA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNIAWGLDCSR------EEKRRRVAALMEMVALD---ATLASHwpheISGGQQQRVALARAL 148
Cdd:PRK13549  83 GIAIIHQELALVKELSVLENIFLGNEITPggimdyDAMYLRAQKLLAQLKLDinpATPVGN----LGLGQQQLVEIAKAL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 149 AQRPSLMLLDEPFSALdtglraaTRKATADLLA------EAGVASILVTHDQTEALSFASQVAVMRQGRFaqVGTpfevy 222
Cdd:PRK13549 159 NKQARLLILDEPTASL-------TESETAVLLDiirdlkAHGIACIYISHKLNEVKAISDTICVIRDGRH--IGT----- 224

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 223 sRPVDEATAlflgDALVldaELMEGRarcAIGELPTDDPHAngRGRVMLRPEqlRVSSCAPQESAFRIVD-VDFA 296
Cdd:PRK13549 225 -RPAAGMTE----DDII---TMMVGR---ELTALYPREPHT--IGEVILEVR--NLTAWDPVNPHIKRVDdVSFS 284
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 16-197 2.07e-27

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 107.17  E-value: 2.07e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA--EGVFVPAHQRGIGFVPQEGALFPHLN 93
Cdd:PRK10584  25 ILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQmdEEARAKLRAKHVGFVFQSFMLIPTLN 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNI---AWGLDCSREEKRRRVAALMEMVALDATLaSHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD--TGL 168
Cdd:PRK10584 105 ALENVelpALLRGESSRQSRNGAKALLEQLGLGKRL-DHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDrqTGD 183

                        170       180       190
                 ....*....|....*....|....*....|...
gi 505180171 169 RaatrkaTADLL----AEAGVASILVTHDQTEA 197
Cdd:PRK10584 184 K------IADLLfslnREHGTTLILVTHDLQLA 210
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 16-216 2.61e-27

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 106.10  E-value: 2.61e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAG--FETPDNGRIVLQGNTLFAEgvfvpAHQRGIGFVPQEGALFPHLN 93
Cdd:cd03213   24 LLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKR-----SFRKIIGYVPQDDILHPTLT 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIawgldcsreekrrRVAALMEmvaldatlashwphEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGlRAATR 173
Cdd:cd03213   99 VRETL-------------MFAAKLR--------------GLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSS-SALQV 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 505180171 174 KATADLLAEAGVASILVTHD-QTEALSFASQVAVMRQGRFAQVG 216
Cdd:cd03213  151 MSLLRRLADTGRTIICSIHQpSSEIFELFDKLLLLSQGRVIYFG 194
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2-221 2.69e-27

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 109.54  E-value: 2.69e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI-VLqgntlfaeGVFVPAHQR--- 77
Cdd:PRK13536  42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKItVL--------GVPVPARARlar 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 -GIGFVPQEGALFPHLNVADN-IAWGLDC--SREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK13536 114 aRIGVVPQFDNLDLEFTVRENlLVFGRYFgmSTREIEAVIPSLLEFARLESK-ADARVSDLSGGMKRRLTLARALINDPQ 192

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:PRK13536 193 LLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 17-218 3.51e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 107.90  E-value: 3.51e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIGFVPQEGALFPhLNVAD 96
Cdd:PRK13647  21 LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLVFQDPDDQVFS-STVWD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  97 NIAWG---LDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATR 173
Cdd:PRK13647 100 DVAFGpvnMGLDKDEVERRVEEALKAVRMWD-FRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLM 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 505180171 174 kATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTP 218
Cdd:PRK13647 179 -EILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK 222
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-230 3.77e-27

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 110.32  E-value: 3.77e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfAEGVFVPAHQRGIG 80
Cdd:PRK09536   3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDD--VEALSARAASRRVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWG-------LDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK09536  81 SVPQDTSLSFEFDVRQVVEMGrtphrsrFDTWTETDRAAVERAMERTGVAQ-FADRPVTSLSGGERQRVLLARALAQATP 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEAT 230
Cdd:PRK09536 160 VLLLDEPTASLDINHQVRTLELVRR-LVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLRAA 235
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-211 4.11e-27

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 107.48  E-value: 4.11e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALV-----LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegVFVPAH 75
Cdd:COG1101    1 MLELKNLSKTFNPGTVnekraLDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDV----TKLPEY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  76 QRG--IGFV---PQEGAlFPHLNVADNIA------------WGLDCSREEKRRRVAALMEM---------VALdatlash 129
Cdd:COG1101   77 KRAkyIGRVfqdPMMGT-APSMTIEENLAlayrrgkrrglrRGLTKKRRELFRELLATLGLglenrldtkVGL------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 130 wpheISGGQQQRVALARALAQRPSLMLLDEPFSALDTglRAATR--KATADLLAEAGVASILVTHDQTEALSFASQVAVM 207
Cdd:COG1101  149 ----LSGGQRQALSLLMATLTKPKLLLLDEHTAALDP--KTAALvlELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMM 222


                 ....
gi 505180171 208 RQGR 211
Cdd:COG1101  223 HEGR 226
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 1-217 4.16e-27

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 111.46  E-value: 4.16e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPD--NGRIVLQGNTLFAEGVfVPAHQRG 78
Cdd:TIGR02633   1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGtwDGEIYWSGSPLKASNI-RDTERAG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   79 IGFVPQEGALFPHLNVADNIAWGLDCSREEKR-------RRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQR 151
Cdd:TIGR02633  80 IVIIHQELTLVPELSVAENIFLGNEITLPGGRmaynamyLRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQ 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171  152 PSLMLLDEPFSALdtglraaTRKATADL------LAEAGVASILVTHDQTEALSFASQVAVMRQGRfaQVGT 217
Cdd:TIGR02633 160 ARLLILDEPSSSL-------TEKETEILldiirdLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ--HVAT 222
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 2-205 4.76e-27

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 103.68  E-value: 4.76e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfvpahqrGIGF 81
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV-------------KIGY 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQegalfphlnvadniawgldcsreekrrrvaalmemvaldatlashwpheISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03221   68 FEQ-------------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPT 98

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 505180171 162 SALDTglraATRKATADLLAEAGVASILVTHDQtealSFASQVA 205
Cdd:cd03221   99 NHLDL----ESIEALEEALKEYPGTVILVSHDR----YFLDQVA 134
cbiO PRK13641
energy-coupling factor transporter ATPase;
17-233 6.35e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 107.61  E-value: 6.35e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAE--GVFVPAHQRGIGFVPQ--EGALFPHl 92
Cdd:PRK13641  23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPEtgNKNLKKLRKKVSLVFQfpEAQLFEN- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 NVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglr 169
Cdd:PRK13641 102 TVLKDVEFGpknFGFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLD---- 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 170 AATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP-------VDE-ATALF 233
Cdd:PRK13641 178 PEGRKEMMQLFKDyqkAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKewlkkhyLDEpATSRF 252
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 12-224 9.46e-27

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 110.58  E-value: 9.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFPH 91
Cdd:TIGR02203 343 RDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDL--ADYTLASLRRQVALVSQDVVLFND 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   92 lNVADNIAWG--LDCSREEKRRRVAA--LMEMV-----ALDATLASHwPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:TIGR02203 421 -TIANNIAYGrtEQADRAEIERALAAayAQDFVdklplGLDTPIGEN-GVLLSGGQRQRLAIARALLKDAPILILDEATS 498

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171  163 ALDTGLRAATRKATADLLaeAGVASILVTHDQTeALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:TIGR02203 499 ALDNESERLVQAALERLM--QGRTTLVIAHRLS-TIEKADRIVVMDDGRIVERGTHNELLAR 557
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 1-196 9.99e-27

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 105.57  E-value: 9.99e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGN---TLFAEgvfvpAHQR 77
Cdd:PRK10247   7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEdisTLKPE-----IYRQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHlNVADNIA--WGLDCSREEKRRRVAALMEMvALDATLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:PRK10247  82 QVSYCAQTPTLFGD-TVYDNLIfpWQIRNQQPDPAIFLDDLERF-ALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVL 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 505180171 156 LLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTE 196
Cdd:PRK10247 160 LLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE 200
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 16-192 1.22e-26

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 110.28  E-value: 1.22e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqgntlfaegvfvPAHQRgIGFVPQ-----EGAL-- 88
Cdd:COG4178  378 LLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR------------PAGAR-VLFLPQrpylpLGTLre 444

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  89 ---FPHLnvADNIawgldcSREEkrrrVAALMEMVALDAtLASH------WPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:COG4178  445 allYPAT--AEAF------SDAE----LREALEAVGLGH-LAERldeeadWDQVLSLGEQQRLAFARLLLHKPDWLFLDE 511

                        170       180       190
                 ....*....|....*....|....*....|...
gi 505180171 160 PFSALDTGLRAATRKATADLLAEAGVasILVTH 192
Cdd:COG4178  512 ATSALDEENEAALYQLLREELPGTTV--ISVGH 542
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 12-217 1.32e-26

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 110.29  E-value: 1.32e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAH--QRGIGFVPQEGALF 89
Cdd:COG5265  369 PERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRD----VTQAslRAAIGIVPQDTVLF 444

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 phlN--VADNIAWG-LDCSREEKRR--RVAALMEMVAldatlasHWPH-----------EISGGQQQRVALARALAQRPS 153
Cdd:COG5265  445 ---NdtIAYNIAYGrPDASEEEVEAaaRAAQIHDFIE-------SLPDgydtrvgerglKLSGGEKQRVAIARTLLKNPP 514

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 154 LMLLDEPFSALDTglraATRKATADLLAEA--GVASILVTHdqteALSF---ASQVAVMRQGRFAQVGT 217
Cdd:COG5265  515 ILIFDEATSALDS----RTERAIQAALREVarGRTTLVIAH----RLSTivdADEILVLEAGRIVERGT 575
cbiO PRK13645
energy-coupling factor transporter ATPase;
17-223 1.54e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 106.63  E-value: 1.54e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqGNTLFAEGVF----VPAHQRGIGFVPQ--EGALFP 90
Cdd:PRK13645  27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIV-GDYAIPANLKkikeVKRLRKEIGLVFQfpEYQLFQ 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  91 HlNVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:PRK13645 106 E-TIEKDIAFGpvnLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPK 184

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 168 LRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:PRK13645 185 GEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS 240
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 2-238 2.10e-26

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 105.31  E-value: 2.10e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDNGRIVLQGNTLFAEGVFVPAHQ 76
Cdd:PRK14267   5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYSPDVDPIEVR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPHLNVADNIAWGLDC-----SREEKRRRV------AALMEMVAldaTLASHWPHEISGGQQQRVALA 145
Cdd:PRK14267  85 REVGMVFQYPNPFPHLTIYDNVAIGVKLnglvkSKKELDERVewalkkAALWDEVK---DRLNDYPSNLSGGQRQRLVIA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 146 RALAQRPSLMLLDEPFSALDTglrAATRKaTADLLAE--AGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:PRK14267 162 RALAMKPKILLMDEPTANIDP---VGTAK-IEELLFElkKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFE 237

                        250
                 ....*....|....*
gi 505180171 224 RPVDEATALFLGDAL 238
Cdd:PRK14267 238 NPEHELTEKYVTGAL 252
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1-210 3.03e-26

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 105.09  E-value: 3.03e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDN---GRIVLQGNTLFAEGVF---VPA 74
Cdd:PRK09984   4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKsagSHIELLGRTVQREGRLardIRK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRGIGFVPQEGALFPHLNVADNIAWG-LDC-----------SREEKRRRVAALMEMVAldatlaSHWPHE----ISGGQ 138
Cdd:PRK09984  84 SRANTGYIFQQFNLVNRLSVLENVLIGaLGStpfwrtcfswfTREQKQRALQALTRVGM------VHFAHQrvstLSGGQ 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171 139 QQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQG 210
Cdd:PRK09984 158 QQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQG 229
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 13-211 3.30e-26

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 104.09  E-value: 3.30e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  13 DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegvfvPAHQ-----RGIGFVPQEGA 87
Cdd:cd03248   26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPI-------SQYEhkylhSKVSLVGQEPV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  88 LFPHlNVADNIAWGL-DCSREE-KRRRVAA-----LMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:cd03248   99 LFAR-SLQDNIAYGLqSCSFECvKEAAQKAhahsfISELASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEA 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 505180171 161 FSALDTGLRAATRKATADLLAEAGVasILVTHdQTEALSFASQVAVMRQGR 211
Cdd:cd03248  178 TSALDAESEQQVQQALYDWPERRTV--LVIAH-RLSTVERADQILVLDGGR 225
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 16-225 4.23e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 104.88  E-value: 4.23e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVPAHQRGIGFVPQEGALFPHlNVA 95
Cdd:PRK13652  19 ALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQNPDDQIFSP-TVE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWG---LDCSREEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAAT 172
Cdd:PRK13652  98 QDIAFGpinLGLDEETVAHRVSSALHMLGLE-ELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKEL 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 505180171 173 RKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK13652 177 IDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
1-242 5.72e-26

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 104.49  E-value: 5.72e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSF-----------ADALvlDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAE 68
Cdd:PRK15112   4 LLEVRNLSKTFryrtgwfrrqtVEAV--KPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLhFGD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  69 GVFVPAHQRGIgFVPQEGALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVAL 144
Cdd:PRK15112  82 YSYRSQRIRMI-FQDPSTSLNPRQRISQILDFPLrlntDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQKQRLGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 145 ARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:PRK15112 161 ARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLAS 240

                        250       260
                 ....*....|....*....|..
gi 505180171 225 PVDEAT----ALFLGDALVLDA 242
Cdd:PRK15112 241 PLHELTkrliAGHFGEALTADA 262
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 1-221 6.08e-26

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 104.01  E-value: 6.08e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegvfVPAHQ--RG 78
Cdd:COG4604    1 MIEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVAT----TPSRElaKR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGldcsR---------EEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALA 149
Cdd:COG4604   77 LAILRQENHINSRLTVRELVAFG----RfpyskgrltAEDREIIDEAIAYLDLED-LADRYLDELSGGQRQRAFIAMVLA 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 150 QRPSLMLLDEPFSALD----TGLRAATRKATADLlaeaGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:COG4604  152 QDTDYVLLDEPLNNLDmkhsVQMMKLLRRLADEL----GKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
cbiO PRK13643
energy-coupling factor transporter ATPase;
11-235 6.18e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 104.82  E-value: 6.18e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  11 FADALVLDnLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGR-----IVLQGNTLFAEgvFVPAHQR-GIGFVPQ 84
Cdd:PRK13643  17 FASRALFD-IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKvtvgdIVVSSTSKQKE--IKPVRKKvGVVFQFP 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  85 EGALFPHlNVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:PRK13643  94 ESQLFEE-TVLKDVAFGpqnFGIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPT 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 162 SALDTGLRAATRKaTADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYsRPVDEATALFLG 235
Cdd:PRK13643 173 AGLDPKARIEMMQ-LFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF-QEVDFLKAHELG 244
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 17-225 9.72e-26

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 108.02  E-value: 9.72e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG---NTLFAEGVfvPAHQRGIGFVPQE--GALFPH 91
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGqriDTLSPGKL--QALRRDIQFIFQDpyASLDPR 417

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 LNVADNIAWGLDCSR----EEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:PRK10261 418 QTVGDSIMEPLRVHGllpgKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVS 497

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 168 LRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK10261 498 IRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENP 555
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
1-211 3.20e-25

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 101.10  E-value: 3.20e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSF-ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA-EGVFVPAHQRG 78
Cdd:PRK10908   1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlKNREVPFLRRQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGL---DCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:PRK10908  81 IGMIFQDHHLLMDRTVYDNVAIPLiiaGASGDDIRRRVSAALDKVGL-LDKAKNFPIQLSGGEQQRVGIARAVVNKPAVL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 156 LLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:PRK10908 160 LADEPTGNLDDALSEGILRLFEE-FNRVGVTVLMATHDIGLISRRSYRMLTLSDGH 214
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 16-221 3.34e-25

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 105.89  E-value: 3.34e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegvfvpaHQ-------RGIGFVPQEGAL 88
Cdd:TIGR01842 333 TLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADL---------KQwdretfgKHIGYLPQDVEL 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   89 FPHlNVADNIAWGLDCSREEKRRRVAALMEMVALDATLASHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:TIGR01842 404 FPG-TVAENIARFGENADPEKIIEAAKLAGVHELILRLPDGYDTVIgpggatlSGGQRQRIALARALYGDPKLVVLDEPN 482

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  162 SALDTGLRAATRKATADLLAeAGVASILVTHdQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:TIGR01842 483 SNLDEEGEQALANAIKALKA-RGITVVVITH-RPSLLGCVDKILVLQDGRIARFGERDEV 540
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 1-238 3.65e-25

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 101.83  E-value: 3.65e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFV--PAHQRG 78
Cdd:TIGR02323   3 LLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAELELYQlsEAERRR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   79 I-----GFVPQEGA--LFPHLNVADNIAWGLDC--SREEKRRRVAAL--MEMVALDATLASHWPHEISGGQQQRVALARA 147
Cdd:TIGR02323  83 LmrtewGFVHQNPRdgLRMRVSAGANIGERLMAigARHYGNIRATAQdwLEEVEIDPTRIDDLPRAFSGGMQQRLQIARN 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  148 LAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVD 227
Cdd:TIGR02323 163 LVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTDQVLDDPQH 242

                         250
                  ....*....|.
gi 505180171  228 EATALFLGDAL 238
Cdd:TIGR02323 243 PYTQLLVSSIL 253
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 1-192 5.70e-25

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 99.95  E-value: 5.70e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfaEGVFVPAHQRGIG 80
Cdd:PRK13539   2 MLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDG-----GDIDDPDVAEACH 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDCsREEKRRRVAALMEMVALDAtlASHWP-HEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:PRK13539  77 YLGHRNAMKPALTVAENLEFWAAF-LGGEELDIAAALEAVGLAP--LAHLPfGYLSAGQKRRVALARLLVSNRPIWILDE 153

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 505180171 160 PFSALDtglrAATRKATADLLA---EAGVASILVTH 192
Cdd:PRK13539 154 PTAALD----AAAVALFAELIRahlAQGGIVIAATH 185
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 2-223 5.97e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 102.47  E-value: 5.97e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADAL-----VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIV-------LQGNTLFAEG 69
Cdd:PRK13651   3 IKVKNIVKIFNKKLptelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEwifkdekNKKKTKEKEK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  70 V---------------FVPAHQRGIGFVPQ--EGALFPHlNVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASH 129
Cdd:PRK13651  83 VleklviqktrfkkikKIKEIRRRVGVVFQfaEYQLFEQ-TIEKDIIFGpvsMGVSKEEAKKRAAKYIELVGLDESYLQR 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 130 WPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTglrAATRKATA--DLLAEAGVASILVTHDQTEALSFASQVAVM 207
Cdd:PRK13651 162 SPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDP---QGVKEILEifDNLNKQGKTIILVTHDLDNVLEWTKRTIFF 238

                        250
                 ....*....|....*.
gi 505180171 208 RQGRFAQVGTPFEVYS 223
Cdd:PRK13651 239 KDGKIIKDGDTYDILS 254
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
15-223 9.78e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 101.32  E-value: 9.78e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  15 LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGVFVPAHQRGIGFVPQEGALFPHLn 93
Cdd:PRK13633  24 LALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGlDTSDEENLWDIRNKAGMVFQNPDNQIVATI- 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIAWG---LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:PRK13633 103 VEEDVAFGpenLGIPPEEIRERVDESLKKVGM-YEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRR 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 505180171 171 ATRKATADLLAEAGVASILVTHDQTEALSfASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:PRK13633 182 EVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFK 233
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
1-192 1.12e-24

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 99.11  E-value: 1.12e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL------FAEGVFVPA 74
Cdd:PRK13538   1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIrrqrdeYHQDLLYLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRGIGfvpqegalfPHLNVADNIAWGLDCSREEKRRRVAALMEMVALDATLasHWP-HEISGGQQQRVALARALAQRPS 153
Cdd:PRK13538  81 HQPGIK---------TELTALENLRFYQRLHGPGDDEALWEALAQVGLAGFE--DVPvRQLSAGQQRRVALARLWLTRAP 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 505180171 154 LMLLDEPFSALDTglraatrKATADLL------AEAGVASILVTH 192
Cdd:PRK13538 150 LWILDEPFTAIDK-------QGVARLEallaqhAEQGGMVILTTH 187
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 17-217 2.27e-24

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 103.77  E-value: 2.27e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDNGRIVLQGNTLFAegvFVPAHQRG-IGFVPQEGALFpHLNVA 95
Cdd:PRK11174 366 AGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIELRE---LDPESWRKhLSWVGQNPQLP-HGTLR 440

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWGLDCSREEKRRRV---AALMEMVALdatLASHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK11174 441 DNVLLGNPDASDEQLQQAlenAWVSEFLPL---LPQGLDTPIgdqaaglSVGQAQRLALARALLQPCQLLLLDEPTASLD 517

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 166 --------TGLRAATRKATAdllaeagvasILVTHdQTEALSFASQVAVMRQGRFAQVGT 217
Cdd:PRK11174 518 ahseqlvmQALNAASRRQTT----------LMVTH-QLEDLAQWDQIWVMQDGQIVQQGD 566
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
6-223 2.38e-24

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 100.06  E-value: 2.38e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   6 SISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL--FAEGVFVpahqRGIGFVP 83
Cdd:PRK10253  12 QLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIqhYASKEVA----RRIGLLA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  84 QEGALFPHLNVADNIAWG-------LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK10253  88 QNATTPGDITVQELVARGryphqplFTRWRKEDEEAVTKAMQATGI-THLADQSVDTLSGGQRQRAWIAMVLAQETAIML 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 157 LDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:PRK10253 167 LDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVT 233
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 1-230 3.10e-24

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 99.46  E-value: 3.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDNGRIVLQGNTLFAEGVFVPAH 75
Cdd:PRK14239   5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHNIYSPRTDTVDL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  76 QRGIGFVPQEGALFPhLNVADNIAWGLdcsreekrrRVAALMEMVALDATL------ASHWP------HE----ISGGQQ 139
Cdd:PRK14239  85 RKEIGMVFQQPNPFP-MSIYENVVYGL---------RLKGIKDKQVLDEAVekslkgASIWDevkdrlHDsalgLSGGQQ 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 140 QRVALARALAQRPSLMLLDEPFSALDTgLRAATRKATADLLAEAgVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPF 219
Cdd:PRK14239 155 QRVCIARVLATSPKIILLDEPTSALDP-ISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTK 232

                        250
                 ....*....|.
gi 505180171 220 EVYSRPVDEAT 230
Cdd:PRK14239 233 QMFMNPKHKET 243
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 2-193 3.46e-24

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 103.21  E-value: 3.46e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADA-LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntLFAEGVFVPAHQRGIG 80
Cdd:TIGR02868 335 LELRDLSAGYPGApPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDG--VPVSSLDQDEVRRRVS 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   81 FVPQEGALFpHLNVADNIAWGL-DCSREEKRR--RVAALMEMVALDATLASHWPHE----ISGGQQQRVALARALAQRPS 153
Cdd:TIGR02868 413 VCAQDAHLF-DTTVRENLRLARpDATDEELWAalERVGLADWLRALPDGLDTVLGEggarLSGGERQRLALARALLADAP 491

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 505180171  154 LMLLDEPFSALDTGLRAATrkaTADLL-AEAGVASILVTHD 193
Cdd:TIGR02868 492 ILLLDEPTEHLDAETADEL---LEDLLaALSGRTVVLITHH 529
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 1-211 3.83e-24

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 99.23  E-value: 3.83e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaEGVFVPAHQRG-- 78
Cdd:PRK11701   6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMR----DGQLRDLYALSea 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 ---------IGFVPQEGA--LFPHLNVADNI-----AWGldcSREEKRRRVAAL--MEMVALDATLASHWPHEISGGQQQ 140
Cdd:PRK11701  82 errrllrteWGFVHQHPRdgLRMQVSAGGNIgerlmAVG---ARHYGDIRATAGdwLERVEIDAARIDDLPTTFSGGMQQ 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 141 RVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:PRK11701 159 RLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGR 229
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 1-248 4.73e-24

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 102.39  E-value: 4.73e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfvPAH--QRG 78
Cdd:PRK10762   4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNG---PKSsqEAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPHLNVADNIAWGldcsrEEKRRRVAALM--EMVA-LDATLA----SHWPH----EISGGQQQRVALARA 147
Cdd:PRK10762  81 IGIIHQELNLIPQLTIAENIFLG-----REFVNRFGRIDwkKMYAeADKLLArlnlRFSSDklvgELSIGEQQMVEIAKV 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 148 LAQRPSLMLLDEPFSALdtglraaTRKATADL------LAEAGVASILVTHDQTEALSFASQVAVMRQGRFaqvgtpfeV 221
Cdd:PRK10762 156 LSFESKVIIMDEPTDAL-------TDTETESLfrvireLKSQGRGIVYISHRLKEIFEICDDVTVFRDGQF--------I 220

                        250       260
                 ....*....|....*....|....*..
gi 505180171 222 YSRPVDEATAlflgDALVldaELMEGR 248
Cdd:PRK10762 221 AEREVADLTE----DSLI---EMMVGR 240
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 16-192 9.66e-24

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 96.66  E-value: 9.66e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfAEGVFVPahQRGIGFVPQEGALFPHLNVA 95
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPL-AEQRDEP--HENILYLGHLPGLKPELSAL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   96 DNIAWGLDCSREEKRRRVAALmEMVALDAtlASHWP-HEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglRAATRK 174
Cdd:TIGR01189  92 ENLHFWAAIHGGAQRTIEDAL-AAVGLTG--FEDLPaAQLSAGQQRRLALARLWLSRRPLWILDEPTTALD---KAGVAL 165

                         170       180
                  ....*....|....*....|
gi 505180171  175 ATADLLA--EAGVASILVTH 192
Cdd:TIGR01189 166 LAGLLRAhlARGGIVLLTTH 185
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 2-230 1.00e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 98.19  E-value: 1.00e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDNGRIVLQGNTLFAEGVFVPAHQ 76
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMnelesEVRVEGRVEFFNQNIYERRVNLNRLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPhLNVADNIAWGLDCSREEKRRRVAALMEMVALDATLASHWPH-------EISGGQQQRVALARALA 149
Cdd:PRK14258  88 RQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDEIKHkihksalDLSGGQQQRLCIARALA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 150 QRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVM-----RQGRFAQVGTPFEVYSR 224
Cdd:PRK14258 167 VKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFkgnenRIGQLVEFGLTKKIFNS 246


                 ....*.
gi 505180171 225 PVDEAT 230
Cdd:PRK14258 247 PHDSRT 252
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 17-221 1.13e-23

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 97.60  E-value: 1.13e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDNGRIVLQGNTLFAEGVFVPAHQRgiGFVPQEGALFPHLNVAD 96
Cdd:COG4138   12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPLSDWSAAELARHR--AYLSQQQSPPFAMPVFQ 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  97 NIAWGLD--CSREEKRRRVAALMEMVALDATLASHWpHEISGGQQQRVALARALAQ-------RPSLMLLDEPFSALDTG 167
Cdd:COG4138   89 YLALHQPagASSEAVEQLLAQLAEALGLEDKLSRPL-TQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLDVA 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 505180171 168 LRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:COG4138  168 QQAALDRLLRE-LCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEV 220
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1-197 1.87e-23

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 101.34  E-value: 1.87e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSF----ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNG--RIVLQGNTLFAEGVFVPA 74
Cdd:PRK10535   4 LLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGtyRVAGQDVATLDADALAQL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRGIGFVPQEGALFPHLNVADNI---AWGLDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQR 151
Cdd:PRK10535  84 RREHFGFIFQRYHLLSHLTAAQNVevpAVYAGLERKQRLLRAQELLQRLGL-EDRVEYQPSQLSGGQQQRVSIARALMNG 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 505180171 152 PSLMLLDEPFSALDTglrAATRKATADL--LAEAGVASILVTHDQTEA 197
Cdd:PRK10535 163 GQVILADEPTGALDS---HSGEEVMAILhqLRDRGHTVIIVTHDPQVA 207
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 1-224 2.28e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 97.61  E-value: 2.28e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADAL-VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL--FAEGVFVPAHQR 77
Cdd:PRK13636   5 ILKVEELNYNYSDGThALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdySRKGLMKLRESV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPhLNVADNIAWG---LDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:PRK13636  85 GMVFQDPDNQLFS-ASVYQDVSFGavnLKLPEDEVRKRVDNALKRTGI-EHLKDKPTHCLSFGQKKRVAIAGVLVMEPKV 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 155 MLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:PRK13636 163 LVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAE 232
cbiO PRK13642
energy-coupling factor transporter ATPase;
12-227 2.81e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 97.47  E-value: 2.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFvpAHQRGIGFVPQE-GALFP 90
Cdd:PRK13642  18 SDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVW--NLRRKIGMVFQNpDNQFV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  91 HLNVADNIAWGLD---CSREEKRRRV-AALMEMVALDatLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:PRK13642  96 GATVEDDVAFGMEnqgIPREEMIKRVdEALLAVNMLD--FKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDP 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 167 GLRAATRKATADLLAEAGVASILVTHDQTEALSfASQVAVMRQGRFAQVGTPFEVYSRPVD 227
Cdd:PRK13642 174 TGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSED 233
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 16-211 3.00e-23

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 96.25  E-value: 3.00e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfaegvFVPAHQRgIGFVPQEGALFPHLNva 95
Cdd:cd03267   36 ALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG--------LVPWKRR-KKFLRRIGVVFGQKT-- 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 dNIAWGL-------------DCSREEKRRRVAALMEMVALDATLasHWP-HEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03267  105 -QLWWDLpvidsfyllaaiyDLPPARFKKRLDELSELLDLEELL--DTPvRQLSLGQRMRAEIAAALLHEPEILFLDEPT 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505180171 162 SALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03267  182 IGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGR 231
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 13-168 4.66e-23

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 95.42  E-value: 4.66e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  13 DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPD---NGRIVLQGNTLFAEGVfvpahQRGIGFVPQEGALF 89
Cdd:cd03234   19 YARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGQPRKPDQF-----QKCVAYVRQDDILL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHLNVADNIAWGL-----DCSREEKRRRVAALMEMVAL-DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03234   94 PGLTVRETLTYTAilrlpRKSSDAIRKKRVEDVLLRDLaLTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSG 173


                 ....*
gi 505180171 164 LDTGL 168
Cdd:cd03234  174 LDSFT 178
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 1-221 4.91e-23

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 95.92  E-value: 4.91e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSF------ADAL----------------VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI 58
Cdd:COG1134    4 MIEVENVSKSYrlyhepSRSLkelllrrrrtrreefwALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  59 VLQGNT--LFAEGVfvpahqrgiGFVPQegalfphLNVADNI-----AWGLdcSREEKRRRVAalmEMVALdATLASHwp 131
Cdd:COG1134   84 EVNGRVsaLLELGA---------GFHPE-------LTGRENIylngrLLGL--SRKEIDEKFD---EIVEF-AELGDF-- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 132 heI-------SGGQQQRVALARALAQRPSLMLLDEpfsALDTGLRAATRKATADL--LAEAGVASILVTHDQTEALSFAS 202
Cdd:COG1134  140 --IdqpvktySSGMRARLAFAVATAVDPDILLVDE---VLAVGDAAFQKKCLARIreLRESGRTVIFVSHSMGAVRRLCD 214

                        250
                 ....*....|....*....
gi 505180171 203 QVAVMRQGRFAQVGTPFEV 221
Cdd:COG1134  215 RAIWLEKGRLVMDGDPEEV 233
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
16-213 6.28e-23

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 99.32  E-value: 6.28e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL----FAEgvfvpAHQRGIGFVP----QEGa 87
Cdd:COG1129  267 VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVrirsPRD-----AIRAGIAYVPedrkGEG- 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  88 LFPHLNVADNIA---------WGLdCSREEKRRRVAALMEMVA-----LDATLAShwpheISGGQQQRVALARALAQRPS 153
Cdd:COG1129  341 LVLDLSIRENITlasldrlsrGGL-LDRRRERALAEEYIKRLRiktpsPEQPVGN-----LSGGNQQKVVLAKWLATDPK 414

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFA 213
Cdd:COG1129  415 VLILDEPTRGIDVGAKAEIYRLIRE-LAAEGKAVIVISSELPELLGLSDRILVMREGRIV 473
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 12-204 6.69e-23

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 93.37  E-value: 6.69e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqgntlfaegvfvPAHqRGIGFVPQEgalfPH 91
Cdd:cd03223   12 DGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM------------PEG-EDLLFLPQR----PY 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 LNVAdniawgldcsreekrrrvaALMEMVALDatlashWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTglraA 171
Cdd:cd03223   75 LPLG-------------------TLREQLIYP------WDDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDE----E 125

                        170       180       190
                 ....*....|....*....|....*....|...
gi 505180171 172 TRKATADLLAEAGVASILVTHdQTEALSFASQV 204
Cdd:cd03223  126 SEDRLYQLLKELGITVISVGH-RPSLWKFHDRV 157
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 1-225 7.40e-23

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 95.44  E-value: 7.40e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVfvPAHQ---R 77
Cdd:PRK11300   5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHI--EGL--PGHQiarM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALF------------PHLNVADNIAWGL------DCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQ 139
Cdd:PRK11300  81 GVVRTFQHVRLFremtvienllvaQHQQLKTGLFSGLlktpafRRAESEALDRAATWLERVGLLE-HANRQAGNLAYGQQ 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 140 QRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPF 219
Cdd:PRK11300 160 RRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPE 239


                 ....*.
gi 505180171 220 EVYSRP 225
Cdd:PRK11300 240 EIRNNP 245
cbiO PRK13646
energy-coupling factor transporter ATPase;
17-223 7.78e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 96.39  E-value: 7.78e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA---EGVFVPAHQRgIGFVPQ--EGALFPH 91
Cdd:PRK13646  23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkDKYIRPVRKR-IGMVFQfpESQLFED 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 lNVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL 168
Cdd:PRK13646 102 -TVEREIIFGpknFKMNLDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQS 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 169 RAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYS 223
Cdd:PRK13646 181 KRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK 235
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 6-235 8.95e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 95.93  E-value: 8.95e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   6 SISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRIL-------AGFETpdNGRIVLQGNTLFAEGVfVPAHQRG 78
Cdd:PRK14271  26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLnrmndkvSGYRY--SGDVLLGGRSIFNYRD-VLEFRRR 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFPhLNVADNIAWGLDCSREEKRRRV-----AALMEMVALDAT--LASHWPHEISGGQQQRVALARALAQR 151
Cdd:PRK14271 103 VGMLFQRPNPFP-MSIMDNVLAGVRAHKLVPRKEFrgvaqARLTEVGLWDAVkdRLSDSPFRLSGGQQQLLCLARTLAVN 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 152 PSLMLLDEPFSALDTGLRAATRKATADLLAEAGVasILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATA 231
Cdd:PRK14271 182 PEVLLLDEPTSALDPTTTEKIEEFIRSLADRLTV--IIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETA 259


                 ....
gi 505180171 232 LFLG 235
Cdd:PRK14271 260 RYVA 263
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 2-218 1.71e-22

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 94.36  E-value: 1.71e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDNGRIVLQGNTLFAEgvfvPAHQR-- 77
Cdd:COG0396    1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILEL----SPDERar 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 -GIGFV---PQEgalFPHLNVAD------NIAWGLDCSREEKRRRVAALMEMVALDATLASHWPHE-ISGGQQQRVALAR 146
Cdd:COG0396   77 aGIFLAfqyPVE---IPGVSVSNflrtalNARRGEELSAREFLKLLKEKMKELGLDEDFLDRYVNEgFSGGEKKRNEILQ 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 147 ALAQRPSLMLLDEPFSALDT-GLRAATRKATAdlLAEAGVASILVTHdQTEALSF--ASQVAVMRQGRFAQVGTP 218
Cdd:COG0396  154 MLLLEPKLAILDETDSGLDIdALRIVAEGVNK--LRSPDRGILIITH-YQRILDYikPDFVHVLVDGRIVKSGGK 225
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 18-238 1.76e-22

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 93.97  E-value: 1.76e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   18 DNLNLTVAPGSRTAIVGPSGSGKTT----LLRILAGFETPDNGRIVLQGNTLFAEGVfvpaHQRGIGFVPQE--GALFPH 91
Cdd:TIGR02770   3 QDLNLSLKRGEVLALVGESGSGKSLtclaILGLLPPGLTQTSGEILLDGRPLLPLSI----RGRHIATIMQNprTAFNPL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   92 LNVADNIAWGLDCS---REEKRRRVAALMEMVALD--ATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:TIGR02770  79 FTMGNHAIETLRSLgklSKQARALILEALEAVGLPdpEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDV 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171  167 GLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFLGDAL 238
Cdd:TIGR02770 159 VNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLSAHL 230
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 2-231 2.05e-22

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 94.46  E-value: 2.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLR-------ILAGFETpdNGRIVLQGNTLFAEGVFVPA 74
Cdd:PRK14243  11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGFRV--EGKVTFHGKNLYAPDVDPVE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRGIGFVPQEGALFPHlNVADNIAWG---------LDcSREEKRRRVAALMEMVA---LDATLAshwpheISGGQQQRV 142
Cdd:PRK14243  89 VRRRIGMVFQKPNPFPK-SIYDNIAYGaringykgdMD-ELVERSLRQAALWDEVKdklKQSGLS------LSGGQQQRL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 143 ALARALAQRPSLMLLDEPFSALDTglrAATRKaTADLLAEAG--VASILVTHDQTEALSFASQVAVM---------RQGR 211
Cdd:PRK14243 161 CIARAIAVQPEVILMDEPCSALDP---ISTLR-IEELMHELKeqYTIIIVTHNMQQAARVSDMTAFFnveltegggRYGY 236

                        250       260
                 ....*....|....*....|
gi 505180171 212 FAQVGTPFEVYSRPVDEATA 231
Cdd:PRK14243 237 LVEFDRTEKIFNSPQQQATR 256
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
1-224 4.91e-22

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 93.92  E-value: 4.91e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL--FAEGVFVPAHQRG 78
Cdd:PRK13638   1 MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdySKRGLLALRQQVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGALFpHLNVADNIAWG---LDCSREEKRRRVAALMEMValDATLASHWPHE-ISGGQQQRVALARALAQRPSL 154
Cdd:PRK13638  81 TVFQDPEQQIF-YTDIDSDIAFSlrnLGVPEAEITRRVDEALTLV--DAQHFRHQPIQcLSHGQKKRVAIAGALVLQARY 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 155 MLLDEPFSALDTGLRAATrKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:PRK13638 158 LLLDEPTAGLDPAGRTQM-IAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFAC 226
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 2-212 5.22e-22

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 91.22  E-value: 5.22e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSF--ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG-NTLFAEGvfvpAHQRG 78
Cdd:cd03247    1 LSINNVSFSYpeQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGvPVSDLEK----ALSSL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEgalfPHLnvadniawgldcsreekrrrvaalmemvaLDATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03247   77 ISVLNQR----PYL-----------------------------FDTTLRNNLGRRFSGGERQRLALARILLQDAPIVLLD 123

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 159 EPFSALDtglrAATRKATADLLAEA--GVASILVTHDQTeALSFASQVAVMRQGRF 212
Cdd:cd03247  124 EPTVGLD----PITERQLLSLIFEVlkDKTLIWITHHLT-GIEHMDKILFLENGKI 174
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 2-224 6.47e-22

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 96.41  E-value: 6.47e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFET--PDNGRIVLQ------------------ 61
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIIYHvalcekcgyverpskvge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   62 -----GNTLFAEGV--------FVPAHQRGIGFVPQEG-ALFPHLNVADNIAWGLD---CSREEKRRRVAALMEMVALDA 124
Cdd:TIGR03269  81 pcpvcGGTLEPEEVdfwnlsdkLRRRIRKRIAIMLQRTfALYGDDTVLDNVLEALEeigYEGKEAVGRAVDLIEMVQLSH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  125 TLaSHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHdQTEALSFASQV 204
Cdd:TIGR03269 161 RI-THIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSH-WPEVIEDLSDK 238

                         250       260
                  ....*....|....*....|.
gi 505180171  205 AV-MRQGRFAQVGTPFEVYSR 224
Cdd:TIGR03269 239 AIwLENGEIKEEGTPDEVVAV 259
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 2-193 8.29e-22

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 96.16  E-value: 8.29e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqGNTLfaegvfvpahqrGIGF 81
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV------------KLAY 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   82 VPQE-GALFPHLNVADNIAWGLD--------------CSR-----EEKRRRVAALmemvaldatlashwpheiSGGQQQR 141
Cdd:TIGR03719 390 VDQSrDALDPNKTVWEEISGGLDiiklgkreipsrayVGRfnfkgSDQQKKVGQL------------------SGGERNR 451

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 505180171  142 VALARALAQRPSLMLLDEPFSALDTglraATRKATAD-LLAEAGVAsILVTHD 193
Cdd:TIGR03719 452 VHLAKTLKSGGNVLLLDEPTNDLDV----ETLRALEEaLLNFAGCA-VVISHD 499
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 16-225 8.55e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 94.15  E-value: 8.55e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQ----GNTLFAEGVFVPAHQRGI----------GF 81
Cdd:PRK13631  41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGdiyiGDKKNNHELITNPYSKKIknfkelrrrvSM 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQ--EGALFPHlNVADNIAWG---LDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK13631 121 VFQfpEYQLFKD-TIEKDIMFGpvaLGVKKSEAKKLAKFYLNKMGLDDSYLERSPFGLSGGQKRRVAIAGILAIQPEILI 199

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171 157 LDEPFSALDtglrAATRKATADLLAEA---GVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK13631 200 FDEPTAGLD----PKGEHEMMQLILDAkanNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQ 267
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 2-217 1.33e-21

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 95.96  E-value: 1.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    2 LELSSISKSFA-DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIG 80
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSL--KDIDRHTLRQFIN 551

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   81 FVPQEGALFPHlNVADNIAWGL-DCSREEKRRRVAALMEM--------VALDATLASHwPHEISGGQQQRVALARALAQR 151
Cdd:TIGR01193 552 YLPQEPYIFSG-SILENLLLGAkENVSQDEIWAACEIAEIkddienmpLGYQTELSEE-GSSISGGQKQRIALARALLTD 629

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171  152 PSLMLLDEPFSALDTGLRaatRKATADLLAEAGVASILVTHdqteALSFASQ---VAVMRQGRFAQVGT 217
Cdd:TIGR01193 630 SKVLILDESTSNLDTITE---KKIVNNLLNLQDKTIIFVAH----RLSVAKQsdkIIVLDHGKIIEQGS 691
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 17-219 1.65e-21

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 95.85  E-value: 1.65e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgvfVPAHQRGIGFVPQEGALFPHLNVAD 96
Cdd:TIGR01257  946 VDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETN---LDAVRQSLGMCPQHNILFHHLTVAE 1022

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    97 NIAWGLDC---SREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrAATR 173
Cdd:TIGR01257 1023 HILFYAQLkgrSWEEAQLEMEAMLEDTGLHHK-RNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVD----PYSR 1097

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 505180171   174 KATADLLAE--AGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPF 219
Cdd:TIGR01257 1098 RSIWDLLLKyrSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPL 1145
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 16-192 1.82e-21

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 90.63  E-value: 1.82e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaeGVFVPAHQRGIGFVPQEGALFPHLNVA 95
Cdd:cd03231   15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPL---DFQRDSIARGLLYLGHAPGIKTTLSVL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIA-WGLDCSREEKRRrvaALMEMvalDATLASHWP-HEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATR 173
Cdd:cd03231   92 ENLRfWHADHSDEQVEE---ALARV---GLNGFEDRPvAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFA 165

                        170
                 ....*....|....*....
gi 505180171 174 KATADLLAEAGVAsILVTH 192
Cdd:cd03231  166 EAMAGHCARGGMV-VLTTH 183
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 16-211 2.26e-21

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 90.67  E-value: 2.26e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGN--TLFAEGVfvpahqrgiGFVPQegalfphLN 93
Cdd:cd03220   37 ALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRvsSLLGLGG---------GFNPE-------LT 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIAWG---LDCSREEKRRRVAALMEMVALDA-------TLAShwpheisgGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03220  101 GRENIYLNgrlLGLSRKEIDEKIDEIIEFSELGDfidlpvkTYSS--------GMKARLAFAIATALEPDILLIDEVLAV 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 505180171 164 LDtglrAATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:cd03220  173 GD----AAFQEKCQRRLREllkQGKTVILVSHDPSSIKRLCDRALVLEKGK 219
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 2-230 2.99e-21

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 94.32  E-value: 2.99e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSIS-KSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVpAHQRGIG 80
Cdd:COG3845  258 LEVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRE-RRRLGVA 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQE---GALFPHLNVADNIA-----------WG-LDcsREEKRRRVAALME-----MVALDATLAShwpheISGGQQQ 140
Cdd:COG3845  337 YIPEDrlgRGLVPDMSVAENLIlgryrrppfsrGGfLD--RKAIRAFAEELIEefdvrTPGPDTPARS-----LSGGNQQ 409

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 141 RVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFaqvgtpfe 220
Cdd:COG3845  410 KVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLE-LRDAGAAVLLISEDLDEILALSDRIAVMYEGRI-------- 480

                        250
                 ....*....|
gi 505180171 221 VYSRPVDEAT 230
Cdd:COG3845  481 VGEVPAAEAT 490
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 2-218 3.48e-21

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 89.51  E-value: 3.48e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDNGRIVLQGNTLFAegvfVPAHQR-- 77
Cdd:cd03217    1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITD----LPPEERar 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 -GIGFVPQEGALFPHLNVADNIawgldcsREekrrrvaalmemvaLDATLashwpheiSGGQQQRVALARALAQRPSLML 156
Cdd:cd03217   77 lGIFLAFQYPPEIPGVKNADFL-------RY--------------VNEGF--------SGGEKKRNEILQLLLLEPDLAI 127

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 157 LDEPFSALD-TGLRAATRkaTADLLAEAGVASILVTHDQtEALSF--ASQVAVMRQGRFAQVGTP 218
Cdd:cd03217  128 LDEPDSGLDiDALRLVAE--VINKLREEGKSVLIITHYQ-RLLDYikPDRVHVLYDGRIVKSGDK 189
cbiO PRK13644
energy-coupling factor transporter ATPase;
1-225 6.41e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 90.82  E-value: 6.41e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADAL-VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlFAEGVF--VPAHQR 77
Cdd:PRK13644   1 MIRLENVSYSYPDGTpALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG---IDTGDFskLQGIRK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGAL-FPHLNVADNIAWG---LDCSREEKRRRVAALMEMVALDaTLASHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK13644  78 LVGIVFQNPETqFVGRTVEEDLAFGpenLCLPPIEIRKRVDRALAEIGLE-KYRHRSPKTLSGGQGQCVALAGILTMEPE 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 154 LMLLDEPFSALD--TGLRAATRkatADLLAEAGVASILVTHDqTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK13644 157 CLIFDEVTSMLDpdSGIAVLER---IKKLHEKGKTIVYITHN-LEELHDADRIIVMDRGKIVLEGEPENVLSDV 226
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
4-229 1.75e-20

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 89.46  E-value: 1.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   4 LSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVP 83
Cdd:PRK10575  14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPL--ESWSSKAFARKVAYLP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  84 QEGALFPHLNVADNIAWG-------LDCSREEKRRRVAALMEMVALDAtLASHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK10575  92 QQLPAAEGMTVRELVAIGrypwhgaLGRFGAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 157 LDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEA 229
Cdd:PRK10575 171 LDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLEQ 243
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 2-217 1.90e-20

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 92.20  E-value: 1.90e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADA--LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL--FAEGvfvpAHQR 77
Cdd:PRK11160 339 LTLNNVSFTYPDQpqPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIadYSEA----ALRQ 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHlNVADNIAWGLDCSREEKrrrVAALMEMVALDATLASH-----WPHE----ISGGQQQRVALARAL 148
Cdd:PRK11160 415 AISVVSQRVHLFSA-TLRDNLLLAAPNASDEA---LIEVLQQVGLEKLLEDDkglnaWLGEggrqLSGGEQRRLGIARAL 490

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 149 AQRPSLMLLDEPFSALDtglrAATRKATADLLAE--AGVASILVTHDQTeALSFASQVAVMRQGRFAQVGT 217
Cdd:PRK11160 491 LHDAPLLLLDEPTEGLD----AETERQILELLAEhaQNKTVLMITHRLT-GLEQFDRICVMDNGQIIEQGT 556
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 16-194 1.94e-20

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 88.09  E-value: 1.94e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDNGRIVLQGNTLfaegvfvpahqrgigfvPQEGALFPHLN 93
Cdd:COG2401   45 VLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQF-----------------GREASLIDAIG 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIAwgldcsreekrrRVAALMEMVAL-DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAAT 172
Cdd:COG2401  108 RKGDFK------------DAVELLNAVGLsDAVLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRV 175

                        170       180
                 ....*....|....*....|..
gi 505180171 173 RKATADLLAEAGVASILVTHDQ 194
Cdd:COG2401  176 ARNLQKLARRAGITLVVATHHY 197
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
2-214 3.29e-20

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 91.13  E-value: 3.29e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGvfVPAHQRGIG 80
Cdd:PRK11288   5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMrFAST--TAALAAGVA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWG--------LDcsREEKRRRVAALMEMVALD----ATLAshwphEISGGQQQRVALARAL 148
Cdd:PRK11288  83 IIYQELHLVPEMTVAENLYLGqlphkggiVN--RRLLNYEAREQLEHLGVDidpdTPLK-----YLSIGQRQMVEIAKAL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 149 AQRPSLMLLDEPFSALDTglRAATR--KATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFAQ 214
Cdd:PRK11288 156 ARNARVIAFDEPTSSLSA--REIEQlfRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 16-279 3.79e-20

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 91.31  E-value: 3.79e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKT-TLLRILAGFETPD----NGRIVLQGNTLFAEGVFVPAHQRG--IGFVPQEG-- 86
Cdd:PRK15134  24 VVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLHASEQTLRGVRGnkIAMIFQEPmv 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  87 ALFPHLNVADNIAWGLDCSReeKRRRVAALMEMVA-LD-------ATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK15134 104 SLNPLHTLEKQLYEVLSLHR--GMRREAARGEILNcLDrvgirqaAKRLTDYPHQLSGGERQRVMIAMALLTRPELLIAD 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATalflgdAL 238
Cdd:PRK15134 182 EPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHPYT------QK 255

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 505180171 239 VLDAElMEGRARcaigELPTDDPhangrgrVMLRPEQLRVS 279
Cdd:PRK15134 256 LLNSE-PSGDPV----PLPEPAS-------PLLDVEQLQVA 284
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 16-193 8.37e-20

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 89.99  E-value: 8.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQgntlfaEGVfvpahqrGIGFVPQEGALFPHLNVA 95
Cdd:TIGR03719  20 ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQ------PGI-------KVGYLPQEPQLDPTKTVR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   96 DNIAWGLDCSREEKRR--RVAALM------------EMVALDATLASHWPHEI-----------------------SGGQ 138
Cdd:TIGR03719  87 ENVEEGVAEIKDALDRfnEISAKYaepdadfdklaaEQAELQEIIDAADAWDLdsqleiamdalrcppwdadvtklSGGE 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 505180171  139 QQRVALARALAQRPSLMLLDEPFSALDtglrAATRKATADLLAEAGVASILVTHD 193
Cdd:TIGR03719 167 RRRVALCRLLLSKPDMLLLDEPTNHLD----AESVAWLERHLQEYPGTVVAVTHD 217
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 1-243 2.25e-19

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 87.47  E-value: 2.25e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFA--DALV--LDNLNLTVAPGSRTAIVGPSGSGKT----TLLRILAGfetpdNGRIvlQGNTLF--AEGV 70
Cdd:PRK09473  12 LLDVKDLRVTFStpDGDVtaVNDLNFSLRAGETLGIVGESGSGKSqtafALMGLLAA-----NGRI--GGSATFngREIL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  71 FVPAHQ------RGIGFVPQE--GALFPHLNVADNIAW------GLDCSR--EEKRRRVAAL--------MEMvaldatl 126
Cdd:PRK09473  85 NLPEKElnklraEQISMIFQDpmTSLNPYMRVGEQLMEvlmlhkGMSKAEafEESVRMLDAVkmpearkrMKM------- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 127 ashWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAV 206
Cdd:PRK09473 158 ---YPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLV 234

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 505180171 207 MRQGRFAQVGTPFEVYSRPVDEATALFLGDALVLDAE 243
Cdd:PRK09473 235 MYAGRTMEYGNARDVFYQPSHPYSIGLLNAVPRLDAE 271
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-193 5.95e-19

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 84.78  E-value: 5.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQgntlfaegvfvpaHQRGIG 80
Cdd:PRK09544   4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRN-------------GKLRIG 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNvadniawgLDCSREEKRR---RVAALMEmvALDATLASH---WP-HEISGGQQQRVALARALAQRPS 153
Cdd:PRK09544  71 YVPQKLYLDTTLP--------LTVNRFLRLRpgtKKEDILP--ALKRVQAGHlidAPmQKLSGGETQRVLLARALLNRPQ 140

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHD 193
Cdd:PRK09544 141 LLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHD 180
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 16-165 7.55e-19

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 87.48  E-value: 7.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqgntlfAEGVfvpahqrGIGFVPQEGALFPHLNVA 95
Cdd:PRK11819  22 ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARP------APGI-------KVGYLPQEPQLDPEKTVR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWGLDCSREEKRR--RVAALM------------EMVALDATLASHWPHEI-----------------------SGGQ 138
Cdd:PRK11819  89 ENVEEGVAEVKAALDRfnEIYAAYaepdadfdalaaEQGELQEIIDAADAWDLdsqleiamdalrcppwdakvtklSGGE 168

                        170       180
                 ....*....|....*....|....*..
gi 505180171 139 QQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK11819 169 RRRVALCRLLLEKPDMLLLDEPTNHLD 195
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 2-193 1.69e-18

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 86.33  E-value: 1.69e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqGNTLfaegvfvpahqrGIGF 81
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV------------KLAY 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQE-GALFPHLNVADNIAWGLD--------------CSR-----EEKRRRVAALmemvaldatlashwpheiSGGQQQR 141
Cdd:PRK11819 392 VDQSrDALDPNKTVWEEISGGLDiikvgnreipsrayVGRfnfkgGDQQKKVGVL------------------SGGERNR 453

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 142 VALARALAQRPSLMLLDEPFSALDT-GLRA---AtrkatadLLAEAGVAsILVTHD 193
Cdd:PRK11819 454 LHLAKTLKQGGNVLLLDEPTNDLDVeTLRAleeA-------LLEFPGCA-VVISHD 501
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 19-225 4.85e-18

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 84.91  E-value: 4.85e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  19 NLNLTVAPGSRTAIVGPSGSGKT----TLLRIL--AGFETPDNGRIVLQGNTLFAE-GVFVPAHQRG-----IGFVPQE- 85
Cdd:PRK10261  34 NLSFSLQRGETLAIVGESGSGKSvtalALMRLLeqAGGLVQCDKMLLRRRSRQVIElSEQSAAQMRHvrgadMAMIFQEp 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  86 -GALFPHLNVADNIAWGL----DCSREEKRRRVAALMEMVAL--DATLASHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK10261 114 mTSLNPVFTVGEQIAESIrlhqGASREEAMVEAKRMLDQVRIpeAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLIAD 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 159 EPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK10261 194 EPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAP 260
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 26-220 4.89e-18

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 85.10  E-value: 4.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   26 PGSRTAIVGPSGSGKTTLLRILAGFETPD---NGRIVLQGNTLFAEgvfvpaHQRGI-GFVPQEGALFPHLNVADNIAW- 100
Cdd:TIGR00955  50 PGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPIDAK------EMRAIsAYVQQDDLFIPTLTVREHLMFq 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  101 -----GLDCSREEKRRRVAALMEMVAL----DATLASHWPHE-ISGGQQQRVALARALAQRPSLMLLDEPFSALDTgLRA 170
Cdd:TIGR00955 124 ahlrmPRRVTKKEKRERVDEVLQALGLrkcaNTRIGVPGRVKgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDS-FMA 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 505180171  171 ATRKATADLLAEAGVASILVTHDQT-EALSFASQVAVMRQGRFAQVGTPFE 220
Cdd:TIGR00955 203 YSVVQVLKGLAQKGKTIICTIHQPSsELFELFDKIILMAEGRVAYLGSPDQ 253
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 1-165 5.18e-18

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 85.00  E-value: 5.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGN----------------T 64
Cdd:PRK11147   3 LISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDlivarlqqdpprnvegT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  65 LF---AEGVfvpAHQ-----------RGIGFVPQEGAL---------FPHLNvadniAWGLDcsreekrRRVAALMEMVA 121
Cdd:PRK11147  83 VYdfvAEGI---EEQaeylkryhdisHLVETDPSEKNLnelaklqeqLDHHN-----LWQLE-------NRINEVLAQLG 147

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 505180171 122 LDA-TLAShwphEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK11147 148 LDPdAALS----SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLD 188
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
12-179 8.97e-18

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 84.30  E-value: 8.97e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFpH 91
Cdd:PRK11176 354 KEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDL--RDYTLASLRNQVALVSQNVHLF-N 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 LNVADNIAWGLD--CSRE--EKRRRVAALMEMV-----ALDaTLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK11176 431 DTIANNIAYARTeqYSREqiEEAARMAYAMDFInkmdnGLD-TVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATS 509

                        170
                 ....*....|....*..
gi 505180171 163 ALDTGLRAATRKATADL 179
Cdd:PRK11176 510 ALDTESERAIQAALDEL 526
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1-248 1.10e-17

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 83.68  E-value: 1.10e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlFAEGVFVPAHQRGIG 80
Cdd:PRK09700   5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNIN-YNKLDHKLAAQLGIG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNI---------AWGLDCSREEKRRRVAALMEM-----VALDATLAshwphEISGGQQQRVALAR 146
Cdd:PRK09700  84 IIYQELSVIDELTVLENLyigrhltkkVCGVNIIDWREMRVRAAMMLLrvglkVDLDEKVA-----NLSISHKQMLEIAK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 147 ALAQRPSLMLLDEPFSALdtglraaTRKATADL------LAEAGVASILVTHDQTEALSFASQVAVMRQGRFaqvgtpfe 220
Cdd:PRK09700 159 TLMLDAKVIIMDEPTSSL-------TNKEVDYLflimnqLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSS-------- 223

                        250       260
                 ....*....|....*....|....*...
gi 505180171 221 VYSRPVDEATalflGDALVldaELMEGR 248
Cdd:PRK09700 224 VCSGMVSDVS----NDDIV---RLMVGR 244
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-211 2.26e-17

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 79.92  E-value: 2.26e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfAEGVFVPAHQRGIG 80
Cdd:PRK11614   5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDI-TDWQTAKIMREAVA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAW-GLDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:PRK11614  84 IVPEGRRVFSRMTVEENLAMgGFFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDE 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 160 PfsalDTGLRAATRKATADL---LAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:PRK11614 164 P----SLGLAPIIIQQIFDTieqLREQGMTIFLVEQNANQALKLADRGYVLENGH 214
PLN03130 PLN03130
ABC transporter C family member; Provisional
 10-220 3.50e-17

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 82.86  E-value: 3.50e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   10 SFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGfETP--DNGRIVLQGNtlfaegvfvpahqrgIGFVPQEGA 87
Cdd:PLN03130  626 SKAERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLG-ELPprSDASVVIRGT---------------VAYVPQVSW 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   88 LFpHLNVADNIAWGL--DCSREEKRRRVAALMEMVAL----DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:PLN03130  690 IF-NATVRDNILFGSpfDPERYERAIDVTALQHDLDLlpggDLTEIGERGVNISGGQKQRVSMARAVYSNSDVYIFDDPL 768

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  162 SALDTGL-RAATRKATADLLaeAGVASILVThDQTEALSFASQVAVMRQGRFAQVGTpFE 220
Cdd:PLN03130  769 SALDAHVgRQVFDKCIKDEL--RGKTRVLVT-NQLHFLSQVDRIILVHEGMIKEEGT-YE 824
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
17-165 3.74e-17

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 82.32  E-value: 3.74e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFpHLNVAD 96
Cdd:PRK13657 351 VEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDI--RTVTRASLRRNIAVVFQDAGLF-NRSIED 427

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171  97 NIAWGLDCSREEKRRRVAALMEmvALD---------ATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK13657 428 NIRVGRPDATDEEMRAAAERAQ--AHDfierkpdgyDTVVGERGRQLSGGERQRLAIARALLKDPPILILDEATSALD 503
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 17-210 5.27e-17

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 78.05  E-value: 5.27e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPD--NGRIVLQGNTLfaegvfVPAHQRGIGFVPQEGALFPHLNV 94
Cdd:cd03232   23 LNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGviTGEILINGRPL------DKNFQRSTGYVEQQDVHSPNLTV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  95 adniawgldcsREekrrrvaalmemvaldATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTglRAA--- 171
Cdd:cd03232   97 -----------RE----------------ALRFSALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDS--QAAyni 147

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 505180171 172 ---TRKatadlLAEAGVAsILVTHDQTEALSFAS--QVAVMRQG 210
Cdd:cd03232  148 vrfLKK-----LADSGQA-ILCTIHQPSASIFEKfdRLLLLKRG 185
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
19-215 6.12e-17

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 81.37  E-value: 6.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  19 NLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFVpAHQRGIGFVPQ---EGALFPHLNVA 95
Cdd:PRK09700 281 DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLD-AVKKGMAYITEsrrDNGFFPNFSIA 359

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIA-------------WGLDCSREEKRRRVAAlMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK09700 360 QNMAisrslkdggykgaMGLFHEVDEQRTAENQ-RELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTR 438

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 505180171 163 ALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQV 215
Cdd:PRK09700 439 GIDVGAKAEIYKVMRQ-LADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
10-175 6.14e-17

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 81.69  E-value: 6.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  10 SFA---DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEG 86
Cdd:PRK10790 347 SFAyrdDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPL--SSLSHSVLRQGVAMVQQDP 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  87 ALFPHlNVADNIAWGLDCSREekrrRVAALMEMVALdATLASHWPHEI-----------SGGQQQRVALARALAQRPSLM 155
Cdd:PRK10790 425 VVLAD-TFLANVTLGRDISEE----QVWQALETVQL-AELARSLPDGLytplgeqgnnlSVGQKQLLALARVLVQTPQIL 498

                        170       180
                 ....*....|....*....|
gi 505180171 156 LLDEPFSALDTGLRAATRKA 175
Cdd:PRK10790 499 ILDEATANIDSGTEQAIQQA 518
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 2-240 9.40e-17

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 78.59  E-value: 9.40e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVlDNLNLTVAPGSRTAIVGPSGSGKT----TLLRILAGFETPDNGRIVLQGNTLfaegvfVPAHQR 77
Cdd:PRK10418   5 IELRNIALQAAQPLV-HGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKPV------APCALR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 G--IGFVPQ--EGALFPHLNVADN-IAWGLDCSREEKRRRVAALMEMVALD--ATLASHWPHEISGGQQQRVALARALAQ 150
Cdd:PRK10418  78 GrkIATIMQnpRSAFNPLHTMHTHaRETCLALGKPADDATLTAALEAVGLEnaARVLKLYPFEMSGGMLQRMMIALALLC 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 151 RPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEAT 230
Cdd:PRK10418 158 EAPFIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVT 237

                        250
                 ....*....|
gi 505180171 231 ALFLGDALVL 240
Cdd:PRK10418 238 RSLVSAHLAL 247
PLN03211 PLN03211
ABC transporter G-25; Provisional
 5-166 2.14e-16

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 80.31  E-value: 2.14e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   5 SSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNgrivLQGNTLFAEGVFVPAHQRGIGFVPQ 84
Cdd:PLN03211  72 SDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNN----FTGTILANNRKPTKQILKRTGFVTQ 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  85 EGALFPHLNVADNIAWgldCS---------REEKRRRVAALMEMVAL----DATLASHWPHEISGGQQQRVALARALAQR 151
Cdd:PLN03211 148 DDILYPHLTVRETLVF---CSllrlpksltKQEKILVAESVISELGLtkceNTIIGNSFIRGISGGERKRVSIAHEMLIN 224

                        170
                 ....*....|....*
gi 505180171 152 PSLMLLDEPFSALDT 166
Cdd:PLN03211 225 PSLLILDEPTSGLDA 239
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 4-212 2.26e-16

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 79.77  E-value: 2.26e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   4 LSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTL-FAEGvfVPAHQRGIGFV 82
Cdd:PRK10982   1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIdFKSS--KEALENGISMV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  83 PQEGALFPHLNVADNIaW-------GLDCSREEKRRRVAALMEMVALD-------ATLashwpheiSGGQQQRVALARAL 148
Cdd:PRK10982  79 HQELNLVLQRSVMDNM-WlgryptkGMFVDQDKMYRDTKAIFDELDIDidprakvATL--------SVSQMQMIEIAKAF 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 149 AQRPSLMLLDEPFSALdtglraaTRKATADL------LAEAGVASILVTHDQTEALSFASQVAVMRQGRF 212
Cdd:PRK10982 150 SYNAKIVIMDEPTSSL-------TEKEVNHLftiirkLKERGCGIVYISHKMEEIFQLCDEITILRDGQW 212
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 15-218 2.67e-16

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 76.76  E-value: 2.67e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  15 LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQG---NTlfaegvfVPAHQ--RGIGFVPQEGALF 89
Cdd:cd03244   18 PVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGvdiSK-------IGLHDlrSRISIIPQDPVLF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHlNVADNiawgLD----CSREEkrrRVAALmEMVALDATLASHWPHE----------ISGGQQQRVALARALAQRPSLM 155
Cdd:cd03244   91 SG-TIRSN----LDpfgeYSDEE---LWQAL-ERVGLKEFVESLPGGLdtvveeggenLSVGQRQLLCLARALLRKSKIL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171 156 LLDEPFSALDTGLRAATRKATADLLAEAGVasILVTHDQTEALSFAsQVAVMRQGRFAQVGTP 218
Cdd:cd03244  162 VLDEATASVDPETDALIQKTIREAFKDCTV--LTIAHRLDTIIDSD-RILVLDKGRVVEFDSP 221
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 7-211 3.80e-16

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 75.76  E-value: 3.80e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   7 ISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGfETPDNGRI---VLQGNTLFAEgvFVPAHQRGIGFVP 83
Cdd:cd03233   13 TGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN-RTEGNVSVegdIHYNGIPYKE--FAEKYPGEIIYVS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  84 QEGALFPHLNVADNIAWGLDCSREEKRRRvaalmemvaldatlashwpheISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03233   90 EEDVHFPTLTVRETLDFALRCKGNEFVRG---------------------ISGGERKRVSIAEALVSRASVLCWDNSTRG 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 505180171 164 LD--TGLRAATR-KATADLLAEAGVASILVTHDqtEALSFASQVAVMRQGR 211
Cdd:cd03233  149 LDssTALEILKCiRTMADVLKTTTFVSLYQASD--EIYDLFDKVLVLYEGR 197
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 2-218 9.53e-16

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 74.76  E-value: 9.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADAL--VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaEGVFVPAHQRGI 79
Cdd:cd03369    7 IEVENLSVRYAPDLppVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDI--STIPLEDLRSSL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  80 GFVPQEGALFphlnvADNIAWGLDCSREEKRRRVAALMEMvaldatlaSHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:cd03369   85 TIIPQDPTLF-----SGTIRSNLDPFDEYSDEEIYGALRV--------SEGGLNLSQGQRQLLCLARALLKRPRVLVLDE 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 505180171 160 PFSALDTGLRAATRKATADLLAEAGVASIlvTHDQTEALSFAsQVAVMRQGRFAQVGTP 218
Cdd:cd03369  152 ATASIDYATDALIQKTIREEFTNSTILTI--AHRLRTIIDYD-KILVMDAGEVKEYDHP 207
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 17-234 1.05e-15

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 78.45  E-value: 1.05e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaegvfvpahqrgIGFVPQEgALFPHLNVAD 96
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS---------------VAYVPQQ-AWIQNDSLRE 717

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    97 NIAWGldCSREEKRRRvaALMEMVAL----------DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:TIGR00957  718 NILFG--KALNEKYYQ--QVLEACALlpdleilpsgDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDA 793

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180171   167 GL-RAATRKATADLLAEAGVASILVTHdqteALSFASQV---AVMRQGRFAQVGTPFEVYSRpvDEATALFL 234
Cdd:TIGR00957  794 HVgKHIFEHVIGPEGVLKNKTRILVTH----GISYLPQVdviIVMSGGKISEMGSYQELLQR--DGAFAEFL 859
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 1-252 1.65e-15

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 76.32  E-value: 1.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALV----LDNLNLTVAPGSRTAIVGPSGSGKT-TLLRILAGFETPdnGRIVLQ-----GNTLFAegv 70
Cdd:PRK11022   3 LLNVDKLSVHFGDESApfraVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYP--GRVMAEklefnGQDLQR--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  71 fVPAHQR------GIGFVPQEG--ALFPHLNVADNIAWGLDC----SREEKRRRVAALMEMVALD--ATLASHWPHEISG 136
Cdd:PRK11022  78 -ISEKERrnlvgaEVAMIFQDPmtSLNPCYTVGFQIMEAIKVhqggNKKTRRQRAIDLLNQVGIPdpASRLDVYPHQLSG 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 137 GQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:PRK11022 157 GMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETG 236

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 505180171 217 TPFEVYSRPVDEATALFLgDALvldAELMEGRARCA 252
Cdd:PRK11022 237 KAHDIFRAPRHPYTQALL-RAL---PEFAQDKARLA 268
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 2-165 7.64e-15

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 75.31  E-value: 7.64e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfvpahqrGIGF 81
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENA-------------NIGY 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 VPQE-GALFPH-LNVADNIA-WGLDCSREEKRRRVAALMEMVALDATLAshwPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK15064 387 YAQDhAYDFENdLTLFDWMSqWRQEGDDEQAVRGTLGRLLFSQDDIKKS---VKVLSGGEKGRMLFGKLMMQKPNVLVMD 463


                 ....*..
gi 505180171 159 EPFSALD 165
Cdd:PRK15064 464 EPTNHMD 470
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 16-225 9.70e-15

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 73.35  E-value: 9.70e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIvlqgntlfaegvfvpAHQRGIGFVPQEGALFPHlNVA 95
Cdd:cd03291   52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI---------------KHSGRISFSSQFSWIMPG-TIK 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWGLdcSREEKRRR--VAA------LMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTg 167
Cdd:cd03291  116 ENIIFGV--SYDEYRYKsvVKAcqleedITKFPEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDV- 192

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 168 lraATRKATAD-----LLAEAgvASILVThDQTEALSFASQVAVMRQGRFAQVGTPFEVYS-RP 225
Cdd:cd03291  193 ---FTEKEIFEscvckLMANK--TRILVT-SKMEHLKKADKILILHEGSSYFYGTFSELQSlRP 250
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 16-165 2.02e-14

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 74.56  E-value: 2.02e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIvlqgntlfaegvfvpAHQRGIGFVPQEGALFPHlNVA 95
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI---------------KHSGRISFSPQTSWIMPG-TIK 504

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171    96 DNIAWGLdcSREEKRRR----VAALMEMVAL----DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:TIGR01271  505 DNIIFGL--SYDEYRYTsvikACQLEEDIALfpekDKTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
16-225 2.03e-14

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 73.02  E-value: 2.03e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDNGRI-----VLQGNTLFAegvfVPAHQR------GIGFVPQ 84
Cdd:COG4170   22 AVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGI-TKDNWHVtadrfRWNGIDLLK----LSPRERrkiigrEIAMIFQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  85 E--GALFPHLNVADNI-----AWGLDCS----REEKRRRVAALMEMVAL---DATLAShWPHEISGGQQQRVALARALAQ 150
Cdd:COG4170   97 EpsSCLDPSAKIGDQLieaipSWTFKGKwwqrFKWRKKRAIELLHRVGIkdhKDIMNS-YPHELTEGECQKVMIAMAIAN 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 151 RPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:COG4170  176 QPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSP 250
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
1-193 2.78e-14

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 73.69  E-value: 2.78e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSfadalvLDNLNLTVAPGS-RT----AIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaegvfvpah 75
Cdd:PRK13409 340 LVEYPDLTKK------LGDFSLEVEGGEiYEgeviGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK------------ 401

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  76 qrgIGFVPQEgaLFPHLNVadniawgldcsreekrrRVAALMEMVAlDATLASHWPHEI-----------------SGGQ 138
Cdd:PRK13409 402 ---ISYKPQY--IKPDYDG-----------------TVEDLLRSIT-DDLGSSYYKSEIikplqlerlldknvkdlSGGE 458

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 139 QQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHD 193
Cdd:PRK13409 459 LQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHD 513
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 17-211 2.94e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 72.43  E-value: 2.94e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGntlfaegvFVP-----AHQRGIGFV-PQEGALFP 90
Cdd:COG4586   38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLG--------YVPfkrrkEFARRIGVVfGQRSQLWW 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  91 HLNVADNIA-----WGLDcsREEKRRRVAALMEMVALDATLasHWP-HEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:COG4586  110 DLPAIDSFRllkaiYRIP--DAEYKKRLDELVELLDLGELL--DTPvRQLSLGQRMRCELAAALLHRPKILFLDEPTIGL 185

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 505180171 165 DTGLRAATRKATADLLAEAGVASILVTHDQT--EALsfASQVAVMRQGR 211
Cdd:COG4586  186 DVVSKEAIREFLKEYNRERGTTILLTSHDMDdiEAL--CDRVIVIDHGR 232
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 1-165 3.17e-14

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 70.36  E-value: 3.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgvfVPAHQRGIG 80
Cdd:PRK13540   1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKD---LCTYQKQLC 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDCSreEKRRRVAALMEMVALDATLasHWP-HEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:PRK13540  78 FVGHRSGINPYLTLRENCLYDIHFS--PGAVGITELCRLFSLEHLI--DYPcGLLSSGQKRQVALLRLWMSKAKLWLLDE 153


                 ....*.
gi 505180171 160 PFSALD 165
Cdd:PRK13540 154 PLVALD 159
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 10-197 4.05e-14

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 73.13  E-value: 4.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  10 SFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGfETPdngrivlQG--N--TLFAEgvfvpahQRG------- 78
Cdd:PRK10938 269 SYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHP-------QGysNdlTLFGR-------RRGsgetiwd 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 ----IGFVpqEGALfpHL---------NVA-----DNIawGLDCSREEKRRRVAA-LMEMVALDATLASHWPHEISGGQQ 139
Cdd:PRK10938 334 ikkhIGYV--SSSL--HLdyrvstsvrNVIlsgffDSI--GIYQAVSDRQQKLAQqWLDILGIDKRTADAPFHSLSWGQQ 407

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171 140 QRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEA 197
Cdd:PRK10938 408 RLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSHHAEDA 465
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 17-210 4.94e-14

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 70.44  E-value: 4.94e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRiVLQGNTLFAEGVFVPAHQRG---IGFVPQEGALFpHLN 93
Cdd:cd03290   17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGK-VHWSNKNESEPSFEATRSRNrysVAYAAQKPWLL-NAT 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIAWGLDCSREekrrRVAALMEMVAL----------DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03290   95 VEENITFGSPFNKQ----RYKAVTDACSLqpdidllpfgDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSA 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 164 LDTGLraatrkatADLLAEAGVAS---------ILVTHdQTEALSFASQVAVMRQG 210
Cdd:cd03290  171 LDIHL--------SDHLMQEGILKflqddkrtlVLVTH-KLQYLPHADWIIAMKDG 217
PLN03232 PLN03232
ABC transporter C family member; Provisional
 17-229 7.27e-14

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 72.70  E-value: 7.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETP-DNGRIVLQGNtlfaegvfvpahqrgIGFVPQEGALFpHLNVA 95
Cdd:PLN03232  633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHaETSSVVIRGS---------------VAYVPQVSWIF-NATVR 696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   96 DNIAWGLD--CSREEKRRRVAALMEMVAL----DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL- 168
Cdd:PLN03232  697 ENILFGSDfeSERYWRAIDVTALQHDLDLlpgrDLTEIGERGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVa 776

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171  169 RAATRKATADLLaeAGVASILVTHD-----QTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEA 229
Cdd:PLN03232  777 HQVFDSCMKDEL--KGKTRVLVTNQlhflpLMDRIILVSEGMIKEEGTFAELSKSGSLFKKLMENA 840
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
17-193 8.67e-14

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 70.30  E-value: 8.67e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIvlqgnTLFAEGVFVPAHQRGIGFVPQEGAL---FPHLn 93
Cdd:PRK15056  23 LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKI-----SILGQPTRQALQKNLVAYVPQSEEVdwsFPVL- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 VADNIAWG-------LDCSREEKRRRVAALMEMVALdatlaSHWPH----EISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK15056  97 VEDVVMMGryghmgwLRRAKKRDRQIVTAALARVDM-----VEFRHrqigELSGGQKKRVFLARAIAQQGQVILLDEPFT 171

                        170       180       190
                 ....*....|....*....|....*....|.
gi 505180171 163 ALDTGLRAATRKATADLLAEaGVASILVTHD 193
Cdd:PRK15056 172 GVDVKTEARIISLLRELRDE-GKTMLVSTHN 201
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
1-192 9.17e-14

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 69.49  E-value: 9.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegVFVPAHQRGIG 80
Cdd:PRK13543  11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKT-----ATRGDRSRFMA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEGALFPHLNVADNIAWGLDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:PRK13543  86 YLGHLPGLKADLSTLENLHFLCGLHGRRAKQMPGSALAIVGL-AGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEP 164

                        170       180       190
                 ....*....|....*....|....*....|...
gi 505180171 161 FSALD-TGLRAATRKATADLlaEAGVASILVTH 192
Cdd:PRK13543 165 YANLDlEGITLVNRMISAHL--RGGGAALVTTH 195
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 19-214 1.35e-13

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 71.24  E-value: 1.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  19 NLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVfVPAHQRGIGFVP---QEGALF---P-H 91
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALST-AQRLARGLVYLPedrQSSGLYldaPlA 359

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 LNVA----DNIAWGLDCSREEK---RRRVAALMEMVALDATLAShwpheISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:PRK15439 360 WNVCalthNRRGFWIKPARENAvleRYRRALNIKFNHAEQAART-----LSGGNQQKVLIAKCLEASPQLLIVDEPTRGV 434

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505180171 165 DTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQ 214
Cdd:PRK15439 435 DVSARNDIYQLIRS-IAAQNVAVLFISSDLEEIEQMADRVLVMHQGEISG 483
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 20-226 1.40e-13

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 69.58  E-value: 1.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  20 LNLTVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDNGRIVLQGNTLFAEGVFVPAHQRGIgFVPQEGALFP-------HL 92
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELARHRAY-LSQQQTPPFAmpvfqylTL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 NVADNiawgldCSREEKRRRVAALMEMVALDATLASHwPHEISGGQQQRVALARALAQ-RPS------LMLLDEPFSALD 165
Cdd:PRK03695  93 HQPDK------TRTEAVASALNEVAEALGLDDKLGRS-VNQLSGGEWQRVRLAAVVLQvWPDinpagqLLLLDEPMNSLD 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 166 TGLRAATRKATaDLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPV 226
Cdd:PRK03695 166 VAQQAALDRLL-SELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPEN 225
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 1-194 1.80e-13

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 71.35  E-value: 1.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqgntlfAEGV---FVPAHQr 77
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL------AKGIklgYFAQHQ- 384

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 gIGFVPQEGALFPHLNvadNIAwgldcsREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK10636 385 -LEFLRADESPLQHLA---RLA------PQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLL 454

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAeagvASILVTHDQ 194
Cdd:PRK10636 455 DEPTNHLDLDMRQALTEALIDFEG----ALVVVSHDR 487
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 17-193 3.00e-13

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 68.59  E-value: 3.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRT-----AIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfvpahqrgIGFVPQ------E 85
Cdd:cd03237   10 LGEFTLEVEGGSISeseviGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDT--------------VSYKPQyikadyE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  86 GALFPHLNVADNIAWGLDCSREEkrrrvaaLMEMVALDATLASHWPhEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:cd03237   76 GTVRDLLSSITKDFYTHPYFKTE-------IAKPLQIEQILDREVP-ELSGGELQRVAIAACLSKDADIYLLDEPSAYLD 147

                        170       180
                 ....*....|....*....|....*...
gi 505180171 166 TGLRAATRKATADLLAEAGVASILVTHD 193
Cdd:cd03237  148 VEQRLMASKVIRRFAENNEKTAFVVEHD 175
PLN03073 PLN03073
ABC transporter F family; Provisional
 10-224 3.78e-13

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 70.27  E-value: 3.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  10 SFADA--------LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegVFVPAHQRGigf 81
Cdd:PLN03073 510 SFSDAsfgypggpLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVRMA--VFSQHHVDG--- 584

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 vpqegalfphLNVADN-IAWGLDCSREEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:PLN03073 585 ----------LDLSSNpLLYMMRCFPGVPEQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEP 654

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 161 FSALDtgLRAATRKATADLLAEAGVasILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:PLN03073 655 SNHLD--LDAVEALIQGLVLFQGGV--LMVSHDEHLISGSVDELWVVSEGKVTPFHGTFHDYKK 714
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
12-217 3.80e-13

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 70.13  E-value: 3.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  12 ADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAegVFVPAHQRGIGFVPQEGALFPH 91
Cdd:PRK10789 326 TDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTK--LQLDSWRSRLAVVSQTPFLFSD 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 lNVADNIAWGLDCSREEKRRRVAALMEMVALDATLASHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:PRK10789 404 -TVANNIALGRPDATQQEIEHVARLASVHDDILRLPQGYDTEVgergvmlSGGQKQRISIARALLLNAEILILDDALSAV 482

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171 165 D--------TGLRAATRKATadllaeagvasILVTHDQTEALSFASQVAVMRQGRFAQVGT 217
Cdd:PRK10789 483 DgrtehqilHNLRQWGEGRT-----------VIISAHRLSALTEASEILVMQHGHIAQRGN 532
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
21-213 4.33e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 69.94  E-value: 4.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  21 NLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfvPAH--QRGIGFVP----QEGaLFPHLNV 94
Cdd:PRK11288 273 SFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRS---PRDaiRAGIMLCPedrkAEG-IIPVHSV 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  95 ADNIA---------WG--LDCSREEK--RRRVAAL--------MEMVALdatlashwpheiSGGQQQRVALARALAQRPS 153
Cdd:PRK11288 349 ADNINisarrhhlrAGclINNRWEAEnaDRFIRSLniktpsreQLIMNL------------SGGNQQKAILGRWLSEDMK 416

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 154 LMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFA 213
Cdd:PRK11288 417 VILLDEPTRGIDVGAKHEIYNVIYE-LAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 16-223 6.18e-13

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 70.06  E-value: 6.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVL---------------QGNTLFAEGV-----FVPAH 75
Cdd:PTZ00265 1183 IYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKNDHHIVfknehtndmtneqdyQGDEEQNVGMknvneFSLTK 1262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   76 QRGIG--------------------------------FVPQEGALFpHLNVADNIAWGL-DCSREEKRR--RVAALMEMV 120
Cdd:PTZ00265 1263 EGGSGedstvfknsgkilldgvdicdynlkdlrnlfsIVSQEPMLF-NMSIYENIKFGKeDATREDVKRacKFAAIDEFI 1341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  121 -----ALDATLAShWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHdQT 195
Cdd:PTZ00265 1342 eslpnKYDTNVGP-YGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH-RI 1419

                         250       260       270
                  ....*....|....*....|....*....|...
gi 505180171  196 EALSFASQVAVM----RQGRFAQV-GTPFEVYS 223
Cdd:PTZ00265 1420 ASIKRSDKIVVFnnpdRTGSFVQAhGTHEELLS 1452
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 2-193 6.53e-13

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 69.43  E-value: 6.53e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFadalvlDNLNLTVAPGS-----RTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaegvfvpahq 76
Cdd:COG1245  342 VEYPDLTKSY------GGFSLEVEGGEiregeVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLK------------- 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 rgIGFVPQEgalfphlnvadniawgLDCSREEkrrRVAALMEMVALDATLASHWPHEI-----------------SGGQQ 139
Cdd:COG1245  403 --ISYKPQY----------------ISPDYDG---TVEEFLRSANTDDFGSSYYKTEIikplgleklldknvkdlSGGEL 461

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 505180171 140 QRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHD 193
Cdd:COG1245  462 QRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHD 515
hmuV PRK13547
heme ABC transporter ATP-binding protein;
16-221 7.10e-13

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 67.93  E-value: 7.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPD--------NGRIVLQGNTLFA---------EGVFVPAHQRG 78
Cdd:PRK13547  16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAidaprlarlRAVLPQAAQPA 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 IGFVPQEGAL---FPHLNVADNIAwgldcsreEKRRRVAALMEMVALDATLASHWPHEISGGQQQRVALARALAQ----- 150
Cdd:PRK13547  96 FAFSAREIVLlgrYPHARRAGALT--------HRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAQlwpph 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 151 ----RPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:PRK13547 168 daaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADV 242
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 17-211 8.88e-13

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 69.08  E-value: 8.88e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAG-FETPDNGRIVLQGNTLFAEGVfVPAHQRGIGFVPQE---GALFPHL 92
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGaYPGKFEGNVFINGKPVDIRNP-AQAIRAGIAMVPEDrkrHGIVPIL 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   93 NVADNIAWGLdCSREEKRRRVAALMEMVALDATL------ASHwPH----EISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:TIGR02633 355 GVGKNITLSV-LKSFCFKMRIDAAAELQIIGSAIqrlkvkTAS-PFlpigRLSGGNQQKAVLAKMLLTNPRVLILDEPTR 432

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 505180171  163 ALDTGLRAATRKATaDLLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:TIGR02633 433 GVDVGAKYEIYKLI-NQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGK 480
PTZ00243 PTZ00243
ABC transporter; Provisional
 16-268 1.93e-12

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 68.27  E-value: 1.93e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAG-FEtpdngrivLQGNTLFAEgvfvpahqRGIGFVPQEgALFPHLNV 94
Cdd:PTZ00243  675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSqFE--------ISEGRVWAE--------RSIAYVPQQ-AWIMNATV 737

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   95 ADNIAWgLDCSREEKRRRVAALMEMVALDATLASHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:PTZ00243  738 RGNILF-FDEEDAARLADAVRVSQLEADLAQLGGGLETEIgekgvnlSGGQKARVSLARAVYANRDVYLLDDPLSALDAH 816

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  168 LraaTRKATADLL--AEAGVASILVTHdQTEALSFASQVAVMRQGRFAQVGTPFEVYSRPVDEATALFL--------GDA 237
Cdd:PTZ00243  817 V---GERVVEECFlgALAGKTRVLATH-QVHVVPRADYVVALGDGRVEFSGSSADFMRTSLYATLAAELkenkdskeGDA 892

                         250       260       270
                  ....*....|....*....|....*....|.
gi 505180171  238 lvlDAELMEGRARCAIGELPtDDPHANGRGR 268
Cdd:PTZ00243  893 ---DAEVAEVDAAPGGAVDH-EPPVAKQEGN 919
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 16-201 2.38e-12

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 68.21  E-value: 2.38e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETpdnGRIVLQGNTLFAEGVFVPAHQRGIGFVPQEGALFPHLNVA 95
Cdd:TIGR00956  778 ILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVT---TGVITGGDRLVNGRPLDSSFQRSIGYVQQQDLHLPTSTVR 854

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    96 DNIAWGL------DCSREEKRRRVAALMEMVAL----DATLAShwPHE-ISGGQQQRVALARALAQRPSLML-LDEPFSA 163
Cdd:TIGR00956  855 ESLRFSAylrqpkSVSKSEKMEYVEEVIKLLEMesyaDAVVGV--PGEgLNVEQRKRLTIGVELVAKPKLLLfLDEPTSG 932

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 505180171   164 LDTGLRAAT----RKatadlLAEAGVAsILVTHDQTEALSFA 201
Cdd:TIGR00956  933 LDSQTAWSIcklmRK-----LADHGQA-ILCTIHQPSAILFE 968
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 1-217 3.10e-12

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 67.73  E-value: 3.10e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171     1 MLELSSISKSFA--DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgvFVPAHQrG 78
Cdd:TIGR01257 1937 ILRLNELTKVYSgtSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTN--ISDVHQ-N 2013

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    79 IGFVPQEGALfphlnvaDNIAWGLDCSREEKRRR--VAALMEMVA------LDATL-ASHWPHEISGGQQQRVALARALA 149
Cdd:TIGR01257 2014 MGYCPQFDAI-------DDLLTGREHLYLYARLRgvPAEEIEKVAnwsiqsLGLSLyADRLAGTYSGGNKRKLSTAIALI 2086

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 505180171   150 QRPSLMLLDEPFSALDTGLRAATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFAQVGT 217
Cdd:TIGR01257 2087 GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGT 2153
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-160 3.38e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 67.46  E-value: 3.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI-VLQGNtlFAEgvfvPAHQRG--- 78
Cdd:NF033858   3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVeVLGGD--MAD----ARHRRAvcp 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  79 -IGFVPQ--EGALFPHLNVADNIA-----WGLDcsREEKRRRVAALMEMVALDATL---ASHwpheISGGQQQRVALARA 147
Cdd:NF033858  77 rIAYMPQglGKNLYPTLSVFENLDffgrlFGQD--AAERRRRIDELLRATGLAPFAdrpAGK----LSGGMKQKLGLCCA 150

                        170
                 ....*....|...
gi 505180171 148 LAQRPSLMLLDEP 160
Cdd:NF033858 151 LIHDPDLLILDEP 163
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 23-193 3.57e-12

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 65.47  E-value: 3.57e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  23 TVAPGSRTAIVGPSGSGKTTLLRILAG--------FETPDNGRIVL---QGNTL---FA---EGVFVPAHQrgigfvPQE 85
Cdd:cd03236   22 VPREGQVLGLVGPNGIGKSTALKILAGklkpnlgkFDDPPDWDEILdefRGSELqnyFTkllEGDVKVIVK------PQY 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  86 GALFPHL---NVADNIawgldcSREEKRRRVAALMEMVALDATLASHWPHeISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:cd03236   96 VDLIPKAvkgKVGELL------KKKDERGKLDELVDQLELRHVLDRNIDQ-LSGGELQRVAIAAALARDADFYFFDEPSS 168

                        170       180       190
                 ....*....|....*....|....*....|.
gi 505180171 163 ALDTGLRAATRKATADlLAEAGVASILVTHD 193
Cdd:cd03236  169 YLDIKQRLNAARLIRE-LAEDDNYVLVVEHD 198
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 26-199 6.87e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 62.39  E-value: 6.87e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    26 PGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqgntlfaegvfvpahqrgigfvpqegalfphlnvadniawgLDCS 105
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----------------------------------------IDGE 39

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   106 REEKRRRVAALMEMVALDatlashwPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA-----ATRKATADLL 180
Cdd:smart00382  40 DILEEVLDQLLLIIVGGK-------KASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEAlllllEELRLLLLLK 112

                          170
                   ....*....|....*....
gi 505180171   181 AEAGVASILVTHDQTEALS 199
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGP 131
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 16-192 3.39e-11

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 64.38  E-value: 3.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIvlqgntlfaegvFVPAHQRgIGFVPQEgalfPHLNVA 95
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRL------------TKPAKGK-LFYVPQR----PYMTLG 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   96 ---DNIAWGlDCSREEKRRRVA-----ALMEMVALDATL--------ASHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:TIGR00954 530 tlrDQIIYP-DSSEDMKRRGLSdkdleQILDNVQLTHILereggwsaVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDE 608

                         170       180       190
                  ....*....|....*....|....*....|...
gi 505180171  160 PFSALDTGLRAATRKatadLLAEAGVASILVTH 192
Cdd:TIGR00954 609 CTSAVSVDVEGYMYR----LCREFGITLFSVSH 637
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 16-211 3.75e-11

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 63.79  E-value: 3.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAG-FETPDNGRIVLQGNTLFAEGvfvPAH--QRGIGFVPQE---GALF 89
Cdd:PRK13549 277 RVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGaYPGRWEGEIFIDGKPVKIRN---PQQaiAQGIAMVPEDrkrDGIV 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHLNVADNIA---------WG-LDCSREEKrrrvAALMEMVALDATLAShwPH----EISGGQQQRVALARALAQRPSLM 155
Cdd:PRK13549 354 PVMGVGKNITlaaldrftgGSrIDDAAELK----TILESIQRLKVKTAS--PElaiaRLSGGNQQKAVLAKCLLLNPKIL 427

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171 156 LLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:PRK13549 428 ILDEPTRGIDVGAKYEIYKLINQ-LVQQGVAIIVISSELPEVLGLSDRVLVMHEGK 482
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-224 4.78e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 63.22  E-value: 4.78e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   2 LELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLlRILAGFETPDNGRIVLQGNTLFAEGvfvPAHQRGIGF 81
Cdd:NF000106  14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TWCANR---RALRRTIG* 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  82 -VPQEGALFPHLNVADN---IAWGLDCSREEKRRRVAALMEMVALDATlASHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:NF000106  90 hRPVR*GRRESFSGRENlymIGR*LDLSRKDARARADELLERFSLTEA-AGRAAAKYSGGMRRRLDLAASMIGRPAVLYL 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 158 DEPFSALDTGLRAATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:NF000106 169 DEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTK 234
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 1-217 5.18e-11

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 61.97  E-value: 5.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFetPD----NGRIVLQGNTLFAEGVFVPAHq 76
Cdd:CHL00131   7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGH--PAykilEGDILFKGESILDLEPEERAH- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  77 RGIGFVPQEGALFPHLNVADNIAwgLDCSREEKRRRVAAL------------MEMVALDATLASHWPHE-ISGGQQQRVA 143
Cdd:CHL00131  84 LGIFLAFQYPIEIPGVSNADFLR--LAYNSKRKFQGLPELdplefleiinekLKLVGMDPSFLSRNVNEgFSGGEKKRNE 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 144 LARALAQRPSLMLLDEPFSALDT-GLRaaTRKATADLLAEAGVASILVTHDQtEALSF--ASQVAVMRQGRFAQVGT 217
Cdd:CHL00131 162 ILQMALLDSELAILDETDSGLDIdALK--IIAEGINKLMTSENSIILITHYQ-RLLDYikPDYVHVMQNGKIIKTGD 235
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 1-216 5.46e-11

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 62.12  E-value: 5.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDNGRIVLQGNTLFA--------EGV 70
Cdd:PRK09580   1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLElspedragEGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  71 FVpAHQRGIGFVPQEGALFphLNVADNIAWGLDCSREEKRRRVAALME----MVALDATLASHWPHE-ISGGQQQRVALA 145
Cdd:PRK09580  81 FM-AFQYPVEIPGVSNQFF--LQTALNAVRSYRGQEPLDRFDFQDLMEekiaLLKMPEDLLTRSVNVgFSGGEKKRNDIL 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 146 RALAQRPSLMLLDEPFSALDT-GLRAATRKATAdlLAEAGVASILVTHDQtEALSFASQ--VAVMRQGRFAQVG 216
Cdd:PRK09580 158 QMAVLEPELCILDESDSGLDIdALKIVADGVNS--LRDGKRSFIIVTHYQ-RILDYIKPdyVHVLYQGRIVKSG 228
PLN03140 PLN03140
ABC transporter G family member; Provisional
 26-171 1.67e-10

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 62.56  E-value: 1.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   26 PGSRTAIVGPSGSGKTTLLRILAGFETPD--NGRIVLQGntlfaegvfVPAHQ----RGIGFVPQEGALFPHLNVADNIA 99
Cdd:PLN03140  905 PGVLTALMGVSGAGKTTLMDVLAGRKTGGyiEGDIRISG---------FPKKQetfaRISGYCEQNDIHSPQVTVRESLI 975

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  100 WGL------DCSREEKRRRVAALMEMVAL----DATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTglR 169
Cdd:PLN03140  976 YSAflrlpkEVSKEEKMMFVDEVMELVELdnlkDAIVGLPGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDA--R 1053


                  ..
gi 505180171  170 AA 171
Cdd:PLN03140 1054 AA 1055
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 16-234 1.82e-10

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 62.43  E-value: 1.82e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILA----GFETPDNGRIVLQGNTLfAEgvFVPaHQRG-IGFVPQEGALFP 90
Cdd:TIGR00956   76 ILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDGITP-EE--IKK-HYRGdVVYNAETDVHFP 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    91 HLNVADNIAWGLDC----------SREEKRRRVAAL-MEMVALDATLASHWPHE----ISGGQQQRVALARALAQRPSLM 155
Cdd:TIGR00956  152 HLTVGETLDFAARCktpqnrpdgvSREEYAKHIADVyMATYGLSHTRNTKVGNDfvrgVSGGERKRVSIAEASLGGAKIQ 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   156 LLDEpfsaLDTGLRAATR-------KATADLLAeagvASILVTHDQT--EALSFASQVAVMRQGRfaqvgtpfEVYSRPV 226
Cdd:TIGR00956  232 CWDN----ATRGLDSATAlefiralKTSANILD----TTPLVAIYQCsqDAYELFDKVIVLYEGY--------QIYFGPA 295


                   ....*...
gi 505180171   227 DEATALFL 234
Cdd:TIGR00956  296 DKAKQYFE 303
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 7-193 3.69e-10

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 58.35  E-value: 3.69e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   7 ISKSFADALVLDNLNlTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTlfaegvfvpahqrgIGFVPQEG 86
Cdd:cd03222    6 CVKRYGVFFLLVELG-VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGIT--------------PVYKPQYI 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  87 ALfphlnvadniawgldcsreekrrrvaalmemvaldatlashwpheiSGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:cd03222   71 DL----------------------------------------------SGGELQRVAIAAALLRNATFYLFDEPSAYLDI 104

                        170       180
                 ....*....|....*....|....*..
gi 505180171 167 GLRAATRKATADLLAEAGVASILVTHD 193
Cdd:cd03222  105 EQRLNAARAIRRLSEEGKKTALVVEHD 131
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 17-211 8.33e-10

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 59.63  E-value: 8.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLfaegvfVPAHqrgigfvPQEGalfphlnVAD 96
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEV------VTRS-------PQDG-------LAN 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  97 NIAWgldcsREEKRRR--------VAALMEMVALD--ATLASHWPHE--------------------------ISGGQQQ 140
Cdd:PRK10762 328 GIVY-----ISEDRKRdglvlgmsVKENMSLTALRyfSRAGGSLKHAdeqqavsdfirlfniktpsmeqaiglLSGGNQQ 402

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 141 RVALARALAQRPSLMLLDEPFSALDTGlraaTRKATADLL---AEAGVASILVTHDQTEALSFASQVAVMRQGR 211
Cdd:PRK10762 403 KVAIARGLMTRPKVLILDEPTRGVDVG----AKKEIYQLInqfKAEGLSIILVSSEMPEVLGMSDRILVMHEGR 472
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 23-193 1.22e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 59.41  E-value: 1.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  23 TVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI--------VLQ---GNTLF------AEGVFVPAHQrgigfvPQE 85
Cdd:COG1245   95 VPKKGKVTGILGPNGIGKSTALKILSGELKPNLGDYdeepswdeVLKrfrGTELQdyfkklANGEIKVAHK------PQY 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  86 GALFPHL---NVADNIawgldcSREEKRRRVAALMEMVALDATlashWPHEI---SGGQQQRVALARALAQRPSLMLLDE 159
Cdd:COG1245  169 VDLIPKVfkgTVRELL------EKVDERGKLDELAEKLGLENI----LDRDIselSGGELQRVAIAAALLRDADFYFFDE 238

                        170       180       190
                 ....*....|....*....|....*....|....
gi 505180171 160 PFSALDTGLRAATRKATADlLAEAGVASILVTHD 193
Cdd:COG1245  239 PSSYLDIYQRLNVARLIRE-LAEEGKYVLVVEHD 271
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 3-193 1.53e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 59.19  E-value: 1.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   3 ELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLqGNTLfaEGVFVPAHQrgigfv 82
Cdd:PRK11147 321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHC-GTKL--EVAYFDQHR------ 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  83 pqeGALFPHLNVADNIAWGldcsREE---------------------KRRR--VAALmemvaldatlashwpheiSGGQQ 139
Cdd:PRK11147 392 ---AELDPEKTVMDNLAEG----KQEvmvngrprhvlgylqdflfhpKRAMtpVKAL------------------SGGER 446

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 505180171 140 QRVALARaLAQRPS-LMLLDEPFSALDTglraATRKATADLLAEAGVASILVTHD 193
Cdd:PRK11147 447 NRLLLAR-LFLKPSnLLILDEPTNDLDV----ETLELLEELLDSYQGTVLLVSHD 496
PLN03232 PLN03232
ABC transporter C family member; Provisional
 16-233 2.58e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 58.83  E-value: 2.58e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVfvPAHQRGIGFVPQEGALFP---HL 92
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGL--TDLRRVLSIIPQSPVLFSgtvRF 1328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   93 NVaDNIAWGLDCSREEKRRRvAALMEMV-----ALDATLaSHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:PLN03232 1329 NI-DPFSEHNDADLWEALER-AHIKDVIdrnpfGLDAEV-SEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVR 1405

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 505180171  168 LRAATRKATADllaEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRpvdEATALF 233
Cdd:PLN03232 1406 TDSLIQRTIRE---EFKSCTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSR---DTSAFF 1465
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
23-193 6.39e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 57.13  E-value: 6.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  23 TVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRI--------VLQ---GNTLF------AEGVFVPAHQrgigfvPQE 85
Cdd:PRK13409  95 IPKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDYeeepswdeVLKrfrGTELQnyfkklYNGEIKVVHK------PQY 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  86 GALFPHL---NVADNIawgldcSREEKRRRVAALMEMVALDATlashWPHEI---SGGQQQRVALARALAQRPSLMLLDE 159
Cdd:PRK13409 169 VDLIPKVfkgKVRELL------KKVDERGKLDEVVERLGLENI----LDRDIselSGGELQRVAIAAALLRDADFYFFDE 238

                        170       180       190
                 ....*....|....*....|....*....|....
gi 505180171 160 PFSALDTGLRAATRKATADLLAEAGVasILVTHD 193
Cdd:PRK13409 239 PTSYLDIRQRLNVARLIRELAEGKYV--LVVEHD 270
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 1-165 8.80e-09

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 56.72  E-value: 8.80e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFA------EGVFVPA 74
Cdd:PRK10636   1 MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNWQLAwvnqetPALPQPA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  75 HQRGIGFVPQEGALFPHLNVA----------------DNI-AWGLdcsreekRRRVAALMEMVALDATLASHWPHEISGG 137
Cdd:PRK10636  81 LEYVIDGDREYRQLEAQLHDAnerndghaiatihgklDAIdAWTI-------RSRAASLLHGLGFSNEQLERPVSDFSGG 153

                        170       180
                 ....*....|....*....|....*...
gi 505180171 138 QQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK10636 154 WRMRLNLAQALICRSDLLLLDEPTNHLD 181
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 13-207 1.08e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 56.96  E-value: 1.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   13 DALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEgVFVPAHQRGIGFVPQEGALFPHl 92
Cdd:PTZ00265  397 DVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSHNLKD-INLKWWRSKIGVVSQDPLLFSN- 474

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   93 NVADNIAWGL-----------------DCSREEKRRRVAA-------------------LMEM-----VALDA------- 124
Cdd:PTZ00265  475 SIKNNIKYSLyslkdlealsnyynedgNDSQENKNKRNSCrakcagdlndmsnttdsneLIEMrknyqTIKDSevvdvsk 554

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  125 ----------------TLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADLLAEAGVASI 188
Cdd:PTZ00265  555 kvlihdfvsalpdkyeTLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITI 634

                         250
                  ....*....|....*....
gi 505180171  189 LVTHdQTEALSFASQVAVM 207
Cdd:PTZ00265  635 IIAH-RLSTIRYANTIFVL 652
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 20-159 1.29e-08

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 55.96  E-value: 1.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  20 LNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEG----------VFVPAHqrgigfvpqegaLF 89
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNreayrqlfsaVFSDFH------------LF 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  90 PHLnvadniaWGLDcsREEKRRRVAALMEMVALD----------ATLAshwpheISGGQQQRVALARALA-QRPsLMLLD 158
Cdd:COG4615  419 DRL-------LGLD--GEADPARARELLERLELDhkvsvedgrfSTTD------LSQGQRKRLALLVALLeDRP-ILVFD 482


                 .
gi 505180171 159 E 159
Cdd:COG4615  483 E 483
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 15-221 1.36e-08

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 56.49  E-value: 1.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    15 LVLDNLNLTVAPGSRTAIVGPSGSGKTT----LLRILAGFEtpdnGRIVLQGNTLFAEGVFVPAHQrgIGFVPQEGALFp 90
Cdd:TIGR00957 1300 LVLRHINVTIHGGEKVGIVGRTGAGKSSltlgLFRINESAE----GEIIIDGLNIAKIGLHDLRFK--ITIIPQDPVLF- 1372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    91 hlnvADNIAWGLDCSREEKRRRVAALMEMVALDaTLASHWP----HE-------ISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:TIGR00957 1373 ----SGSLRMNLDPFSQYSDEEVWWALELAHLK-TFVSALPdkldHEcaeggenLSVGQRQLVCLARALLRKTKILVLDE 1447

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171   160 PFSALDTglraatrkATADLLAeagvASILVTHDQTEALSFA---------SQVAVMRQGRFAQVGTPFEV 221
Cdd:TIGR00957 1448 ATAAVDL--------ETDNLIQ----STIRTQFEDCTVLTIAhrlntimdyTRVIVLDKGEVAEFGAPSNL 1506
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 16-224 1.40e-08

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 54.91  E-value: 1.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLlrILAGFETPD--NGRIVLQGNTLFAegvfVPAH--QRGIGFVPQEGALFph 91
Cdd:cd03288   36 VLKHVKAYIKPGQKVGICGRTGSGKSSL--SLAFFRMVDifDGKIVIDGIDISK----LPLHtlRSRLSIILQDPILF-- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  92 lnvADNIAWGLD----CSREE--KRRRVAALMEMV-----ALDAtLASHWPHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:cd03288  108 ---SGSIRFNLDpeckCTDDRlwEALEIAQLKNMVkslpgGLDA-VVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEA 183

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505180171 161 FSALDTGLRAATRKATADLLAEAGVASIlvTHDQTEALSfASQVAVMRQGRFAQVGTPFEVYSR 224
Cdd:cd03288  184 TASIDMATENILQKVVMTAFADRTVVTI--AHRVSTILD-ADLVLVLSRGILVECDTPENLLAQ 244
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 16-198 2.95e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 55.30  E-value: 2.95e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDnGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALF------ 89
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGVSW--NSVTLQTWRKAFGVIPQKVFIFsgtfrk 1310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171    90 ---PHLNVADNIAWgldcsreekrrRVAalmEMVALDATLaSHWPHE-----------ISGGQQQRVALARALAQRPSLM 155
Cdd:TIGR01271 1311 nldPYEQWSDEEIW-----------KVA---EEVGLKSVI-EQFPDKldfvlvdggyvLSNGHKQLMCLARSILSKAKIL 1375

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 505180171   156 LLDEPFSALDTGLRAATRKATADLLAEAGVasILVTHdQTEAL 198
Cdd:TIGR01271 1376 LLDEPSAHLDPVTLQIIRKTLKQSFSNCTV--ILSEH-RVEAL 1415
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 1-181 4.25e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 52.57  E-value: 4.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDnLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIV---LQGNTLFAEGVFVPAHQR 77
Cdd:PRK13541   1 MLSLHQLQFNIEQKNLFD-LSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYyknCNINNIAKPYCTYIGHNL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFvpqegalfpHLNVADNIA-WGLDCSREEKrrrVAALMEMVALDATLaSHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK13541  80 GLKL---------EMTVFENLKfWSEIYNSAET---LYAAIHYFKLHDLL-DEKCYSLSSGMQKIVAIARLIACQSDLWL 146

                        170       180
                 ....*....|....*....|....*
gi 505180171 157 LDEpfsaLDTGLRAATRKATADLLA 181
Cdd:PRK13541 147 LDE----VETNLSKENRDLLNNLIV 167
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
16-225 5.30e-08

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 53.65  E-value: 5.30e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDNGRIV---LQGNTLFAEGVFVPAHQRGIG------FVPQEG 86
Cdd:PRK15093  22 AVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWRVTadrMRFDDIDLLRLSPRERRKLVGhnvsmiFQEPQS 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  87 ALFPHLNVADNIAWGLDCSREEKR---------RRVAALMEMVALDA--TLASHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:PRK15093 101 CLDPSERVGRQLMQNIPGWTYKGRwwqrfgwrkRRAIELLHRVGIKDhkDAMRSFPYELTEGECQKVMIAIALANQPRLL 180

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 156 LLDEPFSALDTGLRAATRKATADLLAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PRK15093 181 IADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTP 250
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 1-262 6.37e-08

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 53.87  E-value: 6.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   1 MLELSSISKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQgntlFAEGVFVPAHQRGiG 80
Cdd:PRK10938   3 SLQISQGTFRLSDTKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQ----FSHITRLSFEQLQ-K 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  81 FVPQEgalFPHLNvADNIAWGLD----CSRE------EKRRRVAALMEMVALDATLASHWPHeISGGQQQRVALARALAQ 150
Cdd:PRK10938  78 LVSDE---WQRNN-TDMLSPGEDdtgrTTAEiiqdevKDPARCEQLAQQFGITALLDRRFKY-LSTGETRKTLLCQALMS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 151 RPSLMLLDEPFSALDTglraATRKATADLLAE---AGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEVysrpvd 227
Cdd:PRK10938 153 EPDLLILDEPFDGLDV----ASRQQLAELLASlhqSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEI------ 222

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 505180171 228 eatalfLGDALV---------LDAELMEGRARCAIGELPTDDPH 262
Cdd:PRK10938 223 ------LQQALVaqlahseqlEGVQLPEPDEPSARHALPANEPR 260
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 17-165 1.00e-07

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 51.17  E-value: 1.00e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLriLAGFETpdngrivlQGNTLFAEGVFVPAHQRGIgFVPQEGALfphlnvad 96
Cdd:cd03238   11 LQNLDVSIPLNVLVVVTGVSGSGKSTLV--NEGLYA--------SGKARLISFLPKFSRNKLI-FIDQLQFL-------- 71

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180171  97 nIAWGLdcsreekrrrvaalmEMVALDATLAShwpheISGGQQQRVALARALAQRP--SLMLLDEPFSALD 165
Cdd:cd03238   72 -IDVGL---------------GYLTLGQKLST-----LSGGELQRVKLASELFSEPpgTLFILDEPSTGLH 121
PTZ00243 PTZ00243
ABC transporter; Provisional
 15-225 2.25e-07

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 52.86  E-value: 2.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   15 LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGvfVPAHQRGIGFVPQEGALFPHlNV 94
Cdd:PTZ00243 1324 LVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYG--LRELRRQFSMIPQDPVLFDG-TV 1400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   95 ADNIAWGLDCSREEkrrrVAALMEMVALDATLASHWP----------HEISGGQQQRVALARALAQRPS-LMLLDEPFSA 163
Cdd:PTZ00243 1401 RQNVDPFLEASSAE----VWAALELVGLRERVASESEgidsrvleggSNYSVGQRQLMCMARALLKKGSgFILMDEATAN 1476

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171  164 LDTGLraaTRKATADLL-AEAGVASILVTHdQTEALSFASQVAVMRQGRFAQVGTPFEVYSRP 225
Cdd:PTZ00243 1477 IDPAL---DRQIQATVMsAFSAYTVITIAH-RLHTVAQYDKIIVMDHGAVAEMGSPRELVMNR 1535
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 16-214 3.55e-07

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 51.01  E-value: 3.55e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  16 VLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDnGRIVLQGNTLfaEGVFVPAHQRGIGFVPQEGALFphlnvA 95
Cdd:cd03289   19 VLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGVSW--NSVPLQKWRKAFGVIPQKVFIF-----S 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 DNIAWGLD---CSREEKRRRVAalmEMVALdATLASHWPHE-----------ISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03289   91 GTFRKNLDpygKWSDEEIWKVA---EEVGL-KSVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSVLSKAKILLLDEPS 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171 162 SALD----TGLRAATRKATADllaeagvASILVTHDQTEALSFASQVAVMRQGRFAQ 214
Cdd:cd03289  167 AHLDpityQVIRKTLKQAFAD-------CTVILSEHRIEAMLECQRFLVIEENKVRQ 216
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 30-193 6.46e-07

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 49.14  E-value: 6.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  30 TAIVGPSGSGKTTLLR-ILAGF--ETPDNGRIVLQGNTLFAEGvfvpaHQRG---IGFVPQEGALFP---HLNVADNIAW 100
Cdd:cd03240   25 TLIVGQNGAGKTTIIEaLKYALtgELPPNSKGGAHDPKLIREG-----EVRAqvkLAFENANGKKYTitrSLAILENVIF 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 101 gldCSREEKRrrvAALMEMVALdatlashwpheISGGQQQ------RVALARALAQRPSLMLLDEPFSALDTGLRaatRK 174
Cdd:cd03240  100 ---CHQGESN---WPLLDMRGR-----------CSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENI---EE 159

                        170       180
                 ....*....|....*....|...
gi 505180171 175 ATADLLAEAGVAS----ILVTHD 193
Cdd:cd03240  160 SLAEIIEERKSQKnfqlIVITHD 182
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 134-213 9.49e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 47.03  E-value: 9.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 134 ISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAATRKATADlLAEAGVASILVTHDQTEALSFASQVAVMRQGRFA 213
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAE-LAKKDKGIIIISSEMPELLGITDRILVMSNGLVA 470
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
17-216 1.52e-05

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 45.96  E-value: 1.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNtlfaegVFVPAHQRGigfvpqegaLFPHLNVAD 96
Cdd:PRK13546  40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE------VSVIAISAG---------LSGQLTGIE 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  97 NIAWGLDCsREEKRRRVAALMEMVALDATLAS--HWP-HEISGGQQQRVALARALAQRPSLMLLDEpfsALDTGLRAATR 173
Cdd:PRK13546 105 NIEFKMLC-MGFKRKEIKAMTPKIIEFSELGEfiYQPvKKYSSGMRAKLGFSINITVNPDILVIDE---ALSVGDQTFAQ 180

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 505180171 174 KATADL--LAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVG 216
Cdd:PRK13546 181 KCLDKIyeFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYG 225
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 20-211 1.71e-05

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 46.50  E-value: 1.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  20 LNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVFvpAHQRGIGFVPQEGALFPHL------- 92
Cdd:PRK10522 342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPE--DYRKLFSAVFTDFHLFDQLlgpegkp 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  93 -NVADNIAW----GLDCSREEKRRRVAALmemvaldatlashwphEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:PRK10522 420 aNPALVEKWlerlKMAHKLELEDGRISNL----------------KLSKGQKKRLALLLALAEERDILLLDEWAADQDPH 483

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 505180171 168 LRAATRKATADLLAEAGVASILVTHDQtEALSFASQVAVMRQGR 211
Cdd:PRK10522 484 FRREFYQVLLPLLQEMGKTIFAISHDD-HYFIHADRLLEMRNGQ 526
PLN03073 PLN03073
ABC transporter F family; Provisional
 22-165 4.16e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 45.24  E-value: 4.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  22 LTVAPGSRTAIVGPSGSGKTTLLRILAGFET---PDNGRI-------------VLQG--NT------LFAEGVFVPAHQR 77
Cdd:PLN03073 198 VTLAFGRHYGLVGRNGTGKTTFLRYMAMHAIdgiPKNCQIlhveqevvgddttALQCvlNTdiertqLLEEEAQLVAQQR 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  78 GIGFVPQEGALFPHLNVADNI-AWGLDCSREEKR----------RRVAALMEMVALDATLASHWPHEISGGQQQRVALAR 146
Cdd:PLN03073 278 ELEFETETGKGKGANKDGVDKdAVSQRLEEIYKRlelidaytaeARAASILAGLSFTPEMQVKATKTFSGGWRMRIALAR 357

                        170
                 ....*....|....*....
gi 505180171 147 ALAQRPSLMLLDEPFSALD 165
Cdd:PLN03073 358 ALFIEPDLLLLDEPTNHLD 376
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 17-213 5.30e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 43.12  E-value: 5.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLR---ILAGFETPDNGRivlqgNTLFAEGVFVPAhqrgigfvpqegalfphln 93
Cdd:cd03227   11 FVPNDVTFGEGSLTIITGPNGSGKSTILDaigLALGGAQSATRR-----RSGVKAGCIVAA------------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  94 vadniawgldcsreekrrRVAALMEMValdatlashwpHEISGGQQQRVALARALA----QRPSLMLLDEPFSALDTGLR 169
Cdd:cd03227   67 ------------------VSAELIFTR-----------LQLSGGEKELSALALILAlaslKPRPLYILDEIDRGLDPRDG 117

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 505180171 170 AATRKATADLLAEaGVASILVTHDQTEALSFASQVAVMRQGRFA 213
Cdd:cd03227  118 QALAEAILEHLVK-GAQVIVITHLPELAELADKLIHIKKVITGV 160
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 17-221 1.02e-04

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 44.11  E-value: 1.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  17 LDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGN-TLFAEGVFVPAHQRGIGFVPQEGALFphlnva 95
Cdd:PRK13545  40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSaALIAISSGLNGQLTGIENIELKGLMM------ 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  96 dniawGLdcSREEKRRRVAALMEMVALDATLasHWP-HEISGGQQQRVALARALAQRPSLMLLDEpfsALDTGLRAATRK 174
Cdd:PRK13545 114 -----GL--TKEKIKEIIPEIIEFADIGKFI--YQPvKTYSSGMKSRLGFAISVHINPDILVIDE---ALSVGDQTFTKK 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 505180171 175 ATADL--LAEAGVASILVTHDQTEALSFASQVAVMRQGRFAQVGTPFEV 221
Cdd:PRK13545 182 CLDKMneFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV 230
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
8-165 5.51e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 41.65  E-value: 5.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171   8 SKSFADALVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIVLQGNTLFAEGVfvpAHQRGIGFVPQEGA 87
Cdd:NF033858 273 TMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDI---ATRRRVGYMSQAFS 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171  88 LFPHLNVADNI---AWGLDCSREEKRRRVAALMEMVALdATLASHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:NF033858 350 LYGELTVRQNLelhARLFHLPAAEIAARVAEMLERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGV 428


                 .
gi 505180171 165 D 165
Cdd:NF033858 429 D 429
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
 32-60 1.15e-03

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 39.45  E-value: 1.15e-03
                         10        20
                 ....*....|....*....|....*....
gi 505180171  32 IVGPSGSGKTTLLRILAGFeTPDNGRIVL 60
Cdd:cd01130   17 ISGGTGSGKTTLLNALLSF-IPPDERIVT 44
PRK15177 PRK15177
Vi polysaccharide ABC transporter ATP-binding protein VexC;
15-65 1.57e-03

Vi polysaccharide ABC transporter ATP-binding protein VexC;


Pssm-ID: 185099 [Multi-domain]  Cd Length: 213  Bit Score: 39.27  E-value: 1.57e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 505180171  15 LVLDNLNLTVAPGSRTAIVGPSGSGKTTLLRILAGFETPDNGRIV-LQGNTL 65
Cdd:PRK15177   1 VVLDKTDFVMGYHEHIGILAAPGSGKTTLTRLLCGLDAPDEGDFIgLRGDAL 52
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
17-58 2.14e-03

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 39.21  E-value: 2.14e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 505180171  17 LDNLNLTVAPGSR-TAIVGPSGSGKTTLLRILAGFETPDNGRI 58
Cdd:COG3950   14 FEDLEIDFDNPPRlTVLVGENGSGKTTLLEAIALALSGLLSRL 56
GguA NF040905
sugar ABC transporter ATP-binding protein;
135-230 3.01e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 39.39  E-value: 3.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180171 135 SGGQQQRVALARALAQRPSLMLLDEPFSALDTGlraatrkatA--------DLLAEAGVASILVTHDQTEALSFASQVAV 206
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVG---------AkyeiytiiNELAAEGKGVIVISSELPELLGMCDRIYV 476

                         90       100
                 ....*....|....*....|....
gi 505180171 207 MRQGRFaqVGtpfEVysrPVDEAT 230
Cdd:NF040905 477 MNEGRI--TG---EL---PREEAS 492
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 19-75 6.08e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 38.66  E-value: 6.08e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 505180171   19 NLNLTVAPGSRTAIVGPSGSGKTTLLriLAGFETPDNgRIVLQGNTLFAEGVFVPAH 75
Cdd:PRK00635 1508 NLNVSAPLHSLVAISGVSGSGKTSLL--LEGFYKQAC-ALIEKGPSVFSEIIFLDSH 1561
VirB4_CagE TIGR00929
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
 30-83 7.10e-03

type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).


Pssm-ID: 273346 [Multi-domain]  Cd Length: 785  Bit Score: 38.45  E-value: 7.10e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505180171   30 TAIVGPSGSGKTTLLR-ILAGFETPDNGRIV-------LQGNTLFAEGVFVPAHQ-RGIGFVP 83
Cdd:TIGR00929 437 TLIFGPTGSGKTTLLNfLLAQMQKYGGMTIFafdkdrgMEIFIRAFGGAYLEIKDgEPFGFNP 499
AAA_29 pfam13555
P-loop containing region of AAA domain;
18-44 8.93e-03

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 34.11  E-value: 8.93e-03
                          10        20
                  ....*....|....*....|....*..
gi 505180171   18 DNLNLTVAPGSRTAIVGPSGSGKTTLL 44
Cdd:pfam13555  13 DGHTIPIDPRGNTLLTGPSGSGKSTLL 39
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
 32-59 9.72e-03

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 37.45  E-value: 9.72e-03
                         10        20
                 ....*....|....*....|....*...
gi 505180171  32 IVGPSGSGKTTLLRILAGFeTPDNGRIV 59
Cdd:COG4962  187 VSGGTGSGKTTLLNALSGF-IPPDERIV 213
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
135-168 9.91e-03

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 37.70  E-value: 9.91e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 505180171 135 SGGQQQRVALARALAQR---PSLMLLDEPfsalDTGL 168
Cdd:COG0178  828 SGGEAQRVKLASELSKRstgKTLYILDEP----TTGL 860
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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