NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|505180177|ref|WP_015367279|]
View 

hypothetical protein [Klebsiella aerogenes]

Protein Classification

WD40 and YncE domain-containing protein( domain architecture ID 11455443)

WD40 and YncE domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
201-358 1.06e-21

DNA-binding beta-propeller fold protein YncE [General function prediction only];


:

Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 92.83  E-value: 1.06e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 201 VKGAYRGTAYGLTLDEKTQKIYV--GGRDYINEIDARTQQVVRTIPLNApqlaSAQNLIVDSDSGRIFVVAFDHDDrsgp 278
Cdd:COG3391   62 LGAAAVADADGADAGADGRRLYVanSGSGRVSVIDLATGKVVATIPVGG----GPRGLAVDPDGGRLYVADSGNGR---- 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 279 hdgLYIFDLKDGKSLGYVRTGVGANAVRFNPKYNELYVSNFTSGTISVV----DGKTWRVTHEFRAPVYPNQMVLSPDMD 354
Cdd:COG3391  134 ---VSVIDTATGKVVATIPVGAGPHGIAVDPDGKRLYVANSGSNTVSVIvsviDTATGKVVATIPVGGGPVGVAVSPDGR 210


                 ....
gi 505180177 355 TLYV 358
Cdd:COG3391  211 RLYV 214
Vgb super family cl26743
Streptogramin lyase [Defense mechanisms];
33-331 1.57e-08

Streptogramin lyase [Defense mechanisms];


The actual alignment was detected with superfamily member COG4257:

Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 55.03  E-value: 1.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177  33 ASRFAMKTNYLQEANEGVYELAFDNGDNLLFAAAtdrvnraaNKGYLYAFNPATLQVIQrydmpwraFSLAMNQPAHVLY 112
Cdd:COG4257    2 ASAVDITEYPVPAPGSGPRDVAVDPDGAVWFTDQ--------GGGRIGRLDPATGEFTE--------YPLGGGSGPHGIA 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 113 VGH------TQSASLRISQFDAASGKITR--TSPRLSFPTDGAADARfehlrhmvysrsANLLFVSyshmlktQDGmrpl 184
Cdd:COG4257   66 VDPdgnlwfTDNGNNRIGRIDPKTGEITTfaLPGGGSNPHGIAFDPD------------GNLWFTD-------QGG---- 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 185 HKLLMLDGTTLQLKGEVKGAYRGTAYGLTLDEKtQKIYVG--GRDYINEIDARTQQVvRTIPLNAPqLASAQNLIVDSDs 262
Cdd:COG4257  123 NRIGRLDPATGEVTEFPLPTGGAGPYGIAVDPD-GNLWVTdfGANAIGRIDPDTGTL-TEYALPTP-GAGPRGLAVDPD- 198

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180177 263 GRIFVVafDHDDrsgphDGLYIFDLKDGKSLGYVRTGVGAN--AVRFNPkYNELYVSNFTSGTISVVDGKT 331
Cdd:COG4257  199 GNLWVA--DTGS-----GRIGRFDPKTGTVTEYPLPGGGARpyGVAVDG-DGRVWFAESGANRIVRFDPDT 261
 
Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
201-358 1.06e-21

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 92.83  E-value: 1.06e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 201 VKGAYRGTAYGLTLDEKTQKIYV--GGRDYINEIDARTQQVVRTIPLNApqlaSAQNLIVDSDSGRIFVVAFDHDDrsgp 278
Cdd:COG3391   62 LGAAAVADADGADAGADGRRLYVanSGSGRVSVIDLATGKVVATIPVGG----GPRGLAVDPDGGRLYVADSGNGR---- 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 279 hdgLYIFDLKDGKSLGYVRTGVGANAVRFNPKYNELYVSNFTSGTISVV----DGKTWRVTHEFRAPVYPNQMVLSPDMD 354
Cdd:COG3391  134 ---VSVIDTATGKVVATIPVGAGPHGIAVDPDGKRLYVANSGSNTVSVIvsviDTATGKVVATIPVGGGPVGVAVSPDGR 210


                 ....
gi 505180177 355 TLYV 358
Cdd:COG3391  211 RLYV 214
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
33-331 1.57e-08

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 55.03  E-value: 1.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177  33 ASRFAMKTNYLQEANEGVYELAFDNGDNLLFAAAtdrvnraaNKGYLYAFNPATLQVIQrydmpwraFSLAMNQPAHVLY 112
Cdd:COG4257    2 ASAVDITEYPVPAPGSGPRDVAVDPDGAVWFTDQ--------GGGRIGRLDPATGEFTE--------YPLGGGSGPHGIA 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 113 VGH------TQSASLRISQFDAASGKITR--TSPRLSFPTDGAADARfehlrhmvysrsANLLFVSyshmlktQDGmrpl 184
Cdd:COG4257   66 VDPdgnlwfTDNGNNRIGRIDPKTGEITTfaLPGGGSNPHGIAFDPD------------GNLWFTD-------QGG---- 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 185 HKLLMLDGTTLQLKGEVKGAYRGTAYGLTLDEKtQKIYVG--GRDYINEIDARTQQVvRTIPLNAPqLASAQNLIVDSDs 262
Cdd:COG4257  123 NRIGRLDPATGEVTEFPLPTGGAGPYGIAVDPD-GNLWVTdfGANAIGRIDPDTGTL-TEYALPTP-GAGPRGLAVDPD- 198

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180177 263 GRIFVVafDHDDrsgphDGLYIFDLKDGKSLGYVRTGVGAN--AVRFNPkYNELYVSNFTSGTISVVDGKT 331
Cdd:COG4257  199 GNLWVA--DTGS-----GRIGRFDPKTGTVTEYPLPGGGARpyGVAVDG-DGRVWFAESGANRIVRFDPDT 261
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 220-352 6.89e-06

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 47.34  E-value: 6.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177  220 KIYVGGR--DYINEIDARTQQVVRTIPL-NAPQlasaqNLIVDSDSGRIFVVAFDhDDRsgphdgLYIFDLKDGKSLGYV 296
Cdd:TIGR03866  12 TAYVSNEkdNTISVIDTATLKVTRTFPVgQRPR-----GITFSKDGKLLYVCASD-SDT------IQVIDPATGEVLHTL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180177  297 RTGVGANAVRFNPKYNELYVSNFTSGTISVVDGKTWRVTHEFRAPVYPNQMVLSPD 352
Cdd:TIGR03866  80 PSGPDPEQFALHPNGKILYIANEDDALVTVIDIETRKVLAQIDVGVEPEGMAVSPD 135
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 158-343 3.33e-05

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 45.41  E-value: 3.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 158 MVYSRSANLLFVsyshmlKTQDGmrplhKLLMLDGTTLQLKGEVKGAY--RGTAYglTLDEKtqkiYVGGRDYINE---- 231
Cdd:cd20718   64 VVFSPDGRFAYV------ISRDG-----WLTKIDLYTLRPVASIRIGVnsRGIAL--SDDGK----YVIAGNYEPGhvvi 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 232 IDARTQQVVRTIPLNAPQ----LASAQNLIVDSDSGRIFVVAFDhDDRSgphdgLYIFDLKDGKSLGYVR-TGVGAN--- 303
Cdd:cd20718  127 LDADTLEPLKVIPTTGVNddgiIESRVGAILETPPGPYFLVALK-DAGS-----VWVIDYSDPDGNKVTDiGNIGRPlhd 200

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 505180177 304 AVrFNPKYNELYVSNFTSGTISVVDGKTWRVthEFRAPVY 343
Cdd:cd20718  201 AF-LDPDGRYFIVASQGSNTMWVLDLKTGKV--VARIPTG 237
 
Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
201-358 1.06e-21

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 92.83  E-value: 1.06e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 201 VKGAYRGTAYGLTLDEKTQKIYV--GGRDYINEIDARTQQVVRTIPLNApqlaSAQNLIVDSDSGRIFVVAFDHDDrsgp 278
Cdd:COG3391   62 LGAAAVADADGADAGADGRRLYVanSGSGRVSVIDLATGKVVATIPVGG----GPRGLAVDPDGGRLYVADSGNGR---- 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 279 hdgLYIFDLKDGKSLGYVRTGVGANAVRFNPKYNELYVSNFTSGTISVV----DGKTWRVTHEFRAPVYPNQMVLSPDMD 354
Cdd:COG3391  134 ---VSVIDTATGKVVATIPVGAGPHGIAVDPDGKRLYVANSGSNTVSVIvsviDTATGKVVATIPVGGGPVGVAVSPDGR 210


                 ....
gi 505180177 355 TLYV 358
Cdd:COG3391  211 RLYV 214
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
239-358 1.80e-14

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 72.42  E-value: 1.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 239 VVRTIPLNAPQLASAQNLIVDSDSGRIFVVAFDHDDrsgphdgLYIFDLKDGKSLGYVRTGVGANAVRFNPKYNELYVSN 318
Cdd:COG3391   56 LLAGLGLGAAAVADADGADAGADGRRLYVANSGSGR-------VSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVAD 128

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 505180177 319 FTSGTISVVDGKTWRVTHEFRAPVYPNQMVLSPDMDTLYV 358
Cdd:COG3391  129 SGNGRVSVIDTATGKVVATIPVGAGPHGIAVDPDGKRLYV 168
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
185-332 3.40e-13

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 68.57  E-value: 3.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 185 HKLLMLDGTTLQLKGEVKGAYRgtAYGLTLDEKTQKIYV--GGRDYINEIDARTQQVVRTIPLNApqlaSAQNLIVDSDS 262
Cdd:COG3391   90 GRVSVIDLATGKVVATIPVGGG--PRGLAVDPDGGRLYVadSGNGRVSVIDTATGKVVATIPVGA----GPHGIAVDPDG 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 263 GRIFVVAFDhddrsgphDG-----LYIFDLKDGKSLGYVRTGVGANAVRFNPKYNELYVSNFTSG-------TISVVDGK 330
Cdd:COG3391  164 KRLYVANSG--------SNtvsviVSVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYVANRGSNtsnggsnTVSVIDLA 235


                 ..
gi 505180177 331 TW 332
Cdd:COG3391  236 TL 237
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
109-290 1.89e-10

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 60.48  E-value: 1.89e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 109 HVLYVGHTQSAslRISQFDAASGKITRTSPRLSFPtdgaadarfehlRHMVYSRSANLLFVSYSHmlktqdgmrpLHKLL 188
Cdd:COG3391   80 RRLYVANSGSG--RVSVIDLATGKVVATIPVGGGP------------RGLAVDPDGGRLYVADSG----------NGRVS 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 189 MLDGTTLQLKGEVK-GAYrgtAYGLTLDEKTQKIYVGGRD------YINEIDARTQQVVRTIPLnapqLASAQNLIVDSD 261
Cdd:COG3391  136 VIDTATGKVVATIPvGAG---PHGIAVDPDGKRLYVANSGsntvsvIVSVIDTATGKVVATIPV----GGGPVGVAVSPD 208

                        170       180
                 ....*....|....*....|....*....
gi 505180177 262 SGRIFVVAFDHDDRSGPHDGLYIFDLKDG 290
Cdd:COG3391  209 GRRLYVANRGSNTSNGGSNTVSVIDLATL 237
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
33-331 1.57e-08

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 55.03  E-value: 1.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177  33 ASRFAMKTNYLQEANEGVYELAFDNGDNLLFAAAtdrvnraaNKGYLYAFNPATLQVIQrydmpwraFSLAMNQPAHVLY 112
Cdd:COG4257    2 ASAVDITEYPVPAPGSGPRDVAVDPDGAVWFTDQ--------GGGRIGRLDPATGEFTE--------YPLGGGSGPHGIA 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 113 VGH------TQSASLRISQFDAASGKITR--TSPRLSFPTDGAADARfehlrhmvysrsANLLFVSyshmlktQDGmrpl 184
Cdd:COG4257   66 VDPdgnlwfTDNGNNRIGRIDPKTGEITTfaLPGGGSNPHGIAFDPD------------GNLWFTD-------QGG---- 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 185 HKLLMLDGTTLQLKGEVKGAYRGTAYGLTLDEKtQKIYVG--GRDYINEIDARTQQVvRTIPLNAPqLASAQNLIVDSDs 262
Cdd:COG4257  123 NRIGRLDPATGEVTEFPLPTGGAGPYGIAVDPD-GNLWVTdfGANAIGRIDPDTGTL-TEYALPTP-GAGPRGLAVDPD- 198

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505180177 263 GRIFVVafDHDDrsgphDGLYIFDLKDGKSLGYVRTGVGAN--AVRFNPkYNELYVSNFTSGTISVVDGKT 331
Cdd:COG4257  199 GNLWVA--DTGS-----GRIGRFDPKTGTVTEYPLPGGGARpyGVAVDG-DGRVWFAESGANRIVRFDPDT 261
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
233-358 1.20e-06

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 49.31  E-value: 1.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 233 DARTQQVVRTIPLNAPQLASAQNLIVDSDSGRIFVVAFDHDDRSGPHDGLYIFDLKDGKSLGYVRTGVGANAVRFNPKYN 312
Cdd:COG3391    1 ALVASSLLVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGR 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 505180177 313 ELYVSNFTSGTISVVDGKTWRVTHEFRAPVYPNQMVLSPDMDTLYV 358
Cdd:COG3391   81 RLYVANSGSGRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYV 126
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 220-352 6.89e-06

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 47.34  E-value: 6.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177  220 KIYVGGR--DYINEIDARTQQVVRTIPL-NAPQlasaqNLIVDSDSGRIFVVAFDhDDRsgphdgLYIFDLKDGKSLGYV 296
Cdd:TIGR03866  12 TAYVSNEkdNTISVIDTATLKVTRTFPVgQRPR-----GITFSKDGKLLYVCASD-SDT------IQVIDPATGEVLHTL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 505180177  297 RTGVGANAVRFNPKYNELYVSNFTSGTISVVDGKTWRVTHEFRAPVYPNQMVLSPD 352
Cdd:TIGR03866  80 PSGPDPEQFALHPNGKILYIANEDDALVTVIDIETRKVLAQIDVGVEPEGMAVSPD 135
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 312-358 1.21e-05

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 46.57  E-value: 1.21e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 505180177  312 NELYVSNFTSGTISVVDGKTWRVTHEFRAPVYPNQMVLSPDMDTLYV 358
Cdd:TIGR03866  11 ETAYVSNEKDNTISVIDTATLKVTRTFPVGQRPRGITFSKDGKLLYV 57
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 158-343 3.33e-05

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 45.41  E-value: 3.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 158 MVYSRSANLLFVsyshmlKTQDGmrplhKLLMLDGTTLQLKGEVKGAY--RGTAYglTLDEKtqkiYVGGRDYINE---- 231
Cdd:cd20718   64 VVFSPDGRFAYV------ISRDG-----WLTKIDLYTLRPVASIRIGVnsRGIAL--SDDGK----YVIAGNYEPGhvvi 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 232 IDARTQQVVRTIPLNAPQ----LASAQNLIVDSDSGRIFVVAFDhDDRSgphdgLYIFDLKDGKSLGYVR-TGVGAN--- 303
Cdd:cd20718  127 LDADTLEPLKVIPTTGVNddgiIESRVGAILETPPGPYFLVALK-DAGS-----VWVIDYSDPDGNKVTDiGNIGRPlhd 200

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 505180177 304 AVrFNPKYNELYVSNFTSGTISVVDGKTWRVthEFRAPVY 343
Cdd:cd20718  201 AF-LDPDGRYFIVASQGSNTMWVLDLKTGKV--VARIPTG 237
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 185-374 6.36e-05

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 44.64  E-value: 6.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 185 HKLLMLDGTTLQLKGEVKGAYRGT-----------AYGLTLDEKTQKI---------------------------YVGGR 226
Cdd:cd20718   38 GSVLVIDGSTHEVLGRIDDGGAQVhvvvfspdgrfAYVISRDGWLTKIdlytlrpvasirigvnsrgialsddgkYVIAG 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 227 DYINE----IDARTQQVVRTIPLNAPQ----LASAQNLIVDSDSGRIFVVAF---------DHDDRSGP----------- 278
Cdd:cd20718  118 NYEPGhvviLDADTLEPLKVIPTTGVNddgiIESRVGAILETPPGPYFLVALkdagsvwviDYSDPDGNkvtdignigrp 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 279 -HDG------------------LYIFDLKDGKSLGYVRTGV------GANAVRfnpKYNeLYVSNFTSGTISVVDGKTWR 333
Cdd:cd20718  198 lHDAfldpdgryfivasqgsntMWVLDLKTGKVVARIPTGKtphpgpGATWGR---KGV-TATPHLGEGIVTVWDLDTWK 273

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 505180177 334 VTHEFraPVYPNQMVLSPDMDTLYVGIKEGFNREWDPEVFV 374
Cdd:cd20718  274 PVKYI--PTPGPGRFVRTHPSSPYVWADTVFGPENADEIYV 312
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
90-341 4.09e-04

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 41.54  E-value: 4.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177  90 IQRYDMPW---RAFSLAMNQPAHVLYvghTQSASLRISQFDAASGKITRTS-PRLSFPTDgaadarfehlrhMVYSRSAN 165
Cdd:COG4257    7 ITEYPVPApgsGPRDVAVDPDGAVWF---TDQGGGRIGRLDPATGEFTEYPlGGGSGPHG------------IAVDPDGN 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 166 LLFVSYSHmlktqdgmrplHKLLMLDGTTLQLKGEVKGAYRGTAYGLTLDEKtQKIYV--GGRDYINEIDARTQQVvRTI 243
Cdd:COG4257   72 LWFTDNGN-----------NRIGRIDPKTGEITTFALPGGGSNPHGIAFDPD-GNLWFtdQGGNRIGRLDPATGEV-TEF 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 244 PLNAPQlASAQNLIVDSDsGRIFVVAFDHDdrsgphdGLYIFDLKDGKSLGYV--RTGVGANAVRFNPKyNELYVSNFTS 321
Cdd:COG4257  139 PLPTGG-AGPYGIAVDPD-GNLWVTDFGAN-------AIGRIDPDTGTLTEYAlpTPGAGPRGLAVDPD-GNLWVADTGS 208

                        250       260
                 ....*....|....*....|
gi 505180177 322 GTISVVDGKTWRVThEFRAP 341
Cdd:COG4257  209 GRIGRFDPKTGTVT-EYPLP 227
COG3292 COG3292
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
210-336 1.36e-03

Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];


Pssm-ID: 442521 [Multi-domain]  Cd Length: 924  Bit Score: 40.74  E-value: 1.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 210 YGLTLDeKTQKIYVGGRDYINEIDARTQQVVRTIPLNAPQLASAQNLIVDSDsGRIFVvafdhddrsGPHDGLYIFDLKD 289
Cdd:COG3292   84 RALLED-SDGRLWIGTDGGLSRYDPKTDKFTRYPLDPGLPNNSIRSIAEDSD-GNIWV---------GTSNGLYRYDPKT 152

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 505180177 290 GKSLGYVRTGVGANAVR----------FNPKYNELYVSNFTSGtISVVDGKTWRVTH 336
Cdd:COG3292  153 GKFKRFTLDGLPSNTITslaedadgnlWVDSDGNLWIGTDGNG-LYRLDPNTGKFEH 208
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 232-351 1.43e-03

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 40.41  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177  232 IDARTQQVVRTIPLNAPQLASAQ----NLIVDSDSGRIFVVAfdhddrsGPHDGLYIFDLKDGKSLGYVRTGVGANAVRF 307
Cdd:TIGR03866 194 IDVATRKVIKKITFAIPGVHPEKvqpvGIKLTKDGKTAFVAL-------GPANRVAVVDAKTYEVLDYLLVGQRVWQLAF 266

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 505180177  308 NPKYNELYVSNFTSGTISVVDGKTWRVTHEFRAPVYPNQMVLSP 351
Cdd:TIGR03866 267 TPDESRLLTTNGVSNDVSVIDVAALKVIKSIKVGRLPWGVVVRP 310
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 257-358 2.95e-03

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 39.10  E-value: 2.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180177 257 IVDSDSGRIFVVAFDHDDR-----SGPhdGLYIFDLKDGK----SLGYVRTGVGANAVRFNPKyNELYVSNFT----SGT 323
Cdd:COG3386   43 VFAEPSGRPNGLAFDPDGRllvadHGR--GLVRFDPADGEvtvlADEYGKPLNRPNDGVVDPD-GRLYFTDMGeylpTGA 119

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 505180177 324 ISVV--DGKTWRVTHEFrapVYPNQMVLSPDMDTLYV 358
Cdd:COG3386  120 LYRVdpDGSLRVLADGL---TFPNGIAFSPDGRTLYV 153
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 280-358 4.09e-03

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 38.87  E-value: 4.09e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505180177  280 DGLYIFDLKDGKSLGYVRTGVGANAVRFNPKYNELYVSNFTSGTISVVDGKTWRVTHEFRAPVYPNQMVLSPDMDTLYV 358
Cdd:TIGR03866  21 NTISVIDTATLKVTRTFPVGQRPRGITFSKDGKLLYVCASDSDTIQVIDPATGEVLHTLPSGPDPEQFALHPNGKILYI 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH