|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
1-370 |
0e+00 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 623.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 1 MTLNGKRRKVWWLLALVVVIAAIWGWRILNAPLPQYQTLVARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIG 80
Cdd:PRK11578 1 MKKRKKVKKRYLIALVIVLAGGITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 81 DKVQKDQLLGVIDPEQAENQIKEVDATLMELRAQLKQAQAERKLAQVTLARQQQLAQRQLVSRQDLDTAATDVAVKEAQI 160
Cdd:PRK11578 81 DKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTAATELAVKQAQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 161 GTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTLQGQTVIAAQQAPNILTLADLSTMLVKAQVSEADVIHLKPG 240
Cdd:PRK11578 161 GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 241 QKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAIFYYARFEVPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDAIGD 320
Cdd:PRK11578 241 QKAWFTVLGDPLTRYEGVLKDILPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGD 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 505180395 321 NRYNVRLLRNGEVKEREIVIGARNDTDVAVAKGLEEGDEVIISESTPGAT 370
Cdd:PRK11578 321 NRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVIIGEAKPGAA 370
|
|
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
41-363 |
1.05e-71 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 226.75 E-value: 1.05e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 41 ARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEqaenqikEVDATLMELRAQLKQAQA 120
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPP-------DLQAALAQAQAQLAAAQA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 121 ERKLAQVTLARQQQLAQRQLVSRQDLDTAatdvavkEAQIGTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTL 200
Cdd:COG0845 76 QLELAKAELERYKALLKKGAVSQQELDQA-------KAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 201 QGQTVIAAQQapnILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAifYYARFE 280
Cdd:COG0845 149 PGQLVSAGTP---LFTIADLDPLEVEFDVPESDLARLKVGQPVTVTLDAGPGKTFEGKVTFIDPAVDPATRT--VRVRAE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 281 VPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDAiGDNRYNVRLLRNGEVKEREIVIGARNDTDVAVAKGLEEGDEV 360
Cdd:COG0845 224 LPNPDGLLRPGMFVRVRIVLGERENALLVPASAVVRD-GGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRV 302
|
...
gi 505180395 361 IIS 363
Cdd:COG0845 303 VVS 305
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
38-363 |
2.61e-46 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 160.56 E-value: 2.61e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 38 TLVARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEQAEnqikevdATLMELRAQLKQ 117
Cdd:TIGR01730 3 VATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQ-------LALQAALAQLAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 118 AQAERKLAQVTLARQQQLAQRQLVSRQDLDTAATDVAVKeaqigtiEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQI 197
Cdd:TIGR01730 76 AEAQLELAQRSFERAERLVKRNAVSQADLDDAKAAVEAA-------QADLEAAKASLASAQLNLRYTEIRAPFDGTIGRR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 198 TTLQGQTVIAAQqapNILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAIFYYA 277
Cdd:TIGR01730 149 LVEVGAYVTAGQ---TLATIVDLDPLEADFSVPERDLPQLRRGQTLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVRA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 278 RFevPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDaiGDNRYNVRLLRN-GEVKEREIVIGARNDTDVAVAKGLEE 356
Cdd:TIGR01730 226 TF--PNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIE--DLNGKYVYVVKNdGKVSKRPVEVGLRNGGYVEIESGLKA 301
|
....*..
gi 505180395 357 GDEVIIS 363
Cdd:TIGR01730 302 GDQIVTA 308
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
45-294 |
2.55e-16 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 76.78 E-value: 2.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 45 DLQQSVLATGKL--DALRKVDVGAQVSGQLKTLRVN-IGDKVQKDQLLGVID-PEqaenqikevdatlmelraqLKQAQA 120
Cdd:pfam16576 1 PLSRTIRAVGRVayDERRLAHVHARVEGWIEKLYVNaTGDPVKKGQPLAELYsPE-------------------LVAAQQ 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 121 ERKLAqvtlarqqqLAQRQLVSRQDLDTAATD----VAVKEAQIgtieAQIKRNQatldTAKTNLDYTrilAPMSGEVTQ 196
Cdd:pfam16576 62 EYLLA---------LRSGDALSKSELLRAARQrlrlLGMPEAQI----AELERTG----KVQPTVTVY---APISGVVTE 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 197 ITTLQGQTVIAAQqapNILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAIfyY 276
Cdd:pfam16576 122 LNVREGMYVQPGD---TLFTIADLSTVWVEADVPEQDLALVKVGQPAEVTLPALPGKTFEGKVDYIYPTLDPKTRTV--R 196
|
250
....*....|....*...
gi 505180395 277 ARFEVPNPQGILRLEMTA 294
Cdd:pfam16576 197 VRIELPNPDGRLKPGMFA 214
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
1-370 |
0e+00 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 623.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 1 MTLNGKRRKVWWLLALVVVIAAIWGWRILNAPLPQYQTLVARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIG 80
Cdd:PRK11578 1 MKKRKKVKKRYLIALVIVLAGGITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 81 DKVQKDQLLGVIDPEQAENQIKEVDATLMELRAQLKQAQAERKLAQVTLARQQQLAQRQLVSRQDLDTAATDVAVKEAQI 160
Cdd:PRK11578 81 DKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTAATELAVKQAQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 161 GTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTLQGQTVIAAQQAPNILTLADLSTMLVKAQVSEADVIHLKPG 240
Cdd:PRK11578 161 GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 241 QKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAIFYYARFEVPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDAIGD 320
Cdd:PRK11578 241 QKAWFTVLGDPLTRYEGVLKDILPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGD 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 505180395 321 NRYNVRLLRNGEVKEREIVIGARNDTDVAVAKGLEEGDEVIISESTPGAT 370
Cdd:PRK11578 321 NRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVIIGEAKPGAA 370
|
|
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
41-363 |
1.05e-71 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 226.75 E-value: 1.05e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 41 ARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEqaenqikEVDATLMELRAQLKQAQA 120
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPP-------DLQAALAQAQAQLAAAQA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 121 ERKLAQVTLARQQQLAQRQLVSRQDLDTAatdvavkEAQIGTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTL 200
Cdd:COG0845 76 QLELAKAELERYKALLKKGAVSQQELDQA-------KAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 201 QGQTVIAAQQapnILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAifYYARFE 280
Cdd:COG0845 149 PGQLVSAGTP---LFTIADLDPLEVEFDVPESDLARLKVGQPVTVTLDAGPGKTFEGKVTFIDPAVDPATRT--VRVRAE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 281 VPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDAiGDNRYNVRLLRNGEVKEREIVIGARNDTDVAVAKGLEEGDEV 360
Cdd:COG0845 224 LPNPDGLLRPGMFVRVRIVLGERENALLVPASAVVRD-GGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRV 302
|
...
gi 505180395 361 IIS 363
Cdd:COG0845 303 VVS 305
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
38-363 |
2.61e-46 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 160.56 E-value: 2.61e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 38 TLVARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEQAEnqikevdATLMELRAQLKQ 117
Cdd:TIGR01730 3 VATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQ-------LALQAALAQLAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 118 AQAERKLAQVTLARQQQLAQRQLVSRQDLDTAATDVAVKeaqigtiEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQI 197
Cdd:TIGR01730 76 AEAQLELAQRSFERAERLVKRNAVSQADLDDAKAAVEAA-------QADLEAAKASLASAQLNLRYTEIRAPFDGTIGRR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 198 TTLQGQTVIAAQqapNILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAIFYYA 277
Cdd:TIGR01730 149 LVEVGAYVTAGQ---TLATIVDLDPLEADFSVPERDLPQLRRGQTLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVRA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 278 RFevPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDaiGDNRYNVRLLRN-GEVKEREIVIGARNDTDVAVAKGLEE 356
Cdd:TIGR01730 226 TF--PNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIE--DLNGKYVYVVKNdGKVSKRPVEVGLRNGGYVEIESGLKA 301
|
....*..
gi 505180395 357 GDEVIIS 363
Cdd:TIGR01730 302 GDQIVTA 308
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
6-300 |
5.96e-40 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 144.04 E-value: 5.96e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 6 KRRKVWWLLALVVVIAAIWGWRILNAPLPQyqtlvarksdlqQSVLATGKLDAlRKVDVGAQVSGQLKTLRVNIGDKVQK 85
Cdd:COG1566 3 ALKKRRLLALVLLLLALGLALWAAGRNGPD------------EPVTADGRVEA-RVVTVAAKVSGRVTEVLVKEGDRVKK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 86 DQLLGVIDP-------EQAENQIKEVDATL-------------MELRAQLKQAQAERKLAQVTLARQQQLAQRQLVSRQD 145
Cdd:COG1566 70 GQVLARLDPtdlqaalAQAEAQLAAAEAQLarleaelgaeaeiAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQQE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 146 LDTAATDVAVKEAQ--------------------IGTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTLQGQTV 205
Cdd:COG1566 150 LDEARAALDAAQAQleaaqaqlaqaqaglreeeeLAAAQAQVAQAEAALAQAELNLARTTIRAPVDGVVTNLNVEPGEVV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 206 IAAQQapnILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKV--------NDAIFYYA 277
Cdd:COG1566 230 SAGQP---LLTIVPLDDLWVEAYVPETDLGRVKPGQPVEVRVDAYPDRVFEGKVTSISPGAGFTsppknatgNVVQRYPV 306
|
330 340
....*....|....*....|....
gi 505180395 278 RFEVPNPQGI-LRLEMTAQVHIQL 300
Cdd:COG1566 307 RIRLDNPDPEpLRPGMSATVEIDT 330
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
4-369 |
1.43e-23 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 101.02 E-value: 1.43e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 4 NGKRRKVWWLLALVVV--IAAIWGWR--------------------------ILNAPLPQYQTLVARKSDLQQSVLATGK 55
Cdd:PRK11556 2 KGSRKSRWVIVIVVVIaaIAAFWFWQgrstsssaapgaakqaqqspaggrrgMRSGPLAPVQAATATEQAVPRYLTGLGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 56 LDALRKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPE-------QAENQIKEVDATLMELRAQLKQAQaerKLAQVT 128
Cdd:PRK11556 82 VTAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRpfkvalaQAQGQLAKDQATLANARRDLARYQ---QLAKTN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 129 larqqqlaqrqLVSRQDLDTaatdvavKEAQIGTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEV--------TQITTl 200
Cdd:PRK11556 159 -----------LVSRQELDA-------QQALVSETEGTIKADEASVASAQLQLDYSRITAPISGRVglkqvdvgNQISS- 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 201 qGQT---VIAAQQAP--NILTL--ADLSTMLvKAQVSEADVIhlkpgQKAWFTVLGDPLTryEGTLKDILPTPEKVNDAI 273
Cdd:PRK11556 220 -GDTtgiVVITQTHPidLVFTLpeSDIATVV-QAQKAGKPLV-----VEAWDRTNSKKLS--EGTLLSLDNQIDATTGTI 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 274 FYYARFevPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALgdAIGDNRYNVRLLRN-GEVKEREIVIGARNDTDVAVAK 352
Cdd:PRK11556 291 KLKARF--NNQDDALFPNQFVNARMLVDTLQNAVVIPTAAL--QMGNEGHFVWVLNDeNKVSKHLVTPGIQDSQKVVISA 366
|
410 420
....*....|....*....|
gi 505180395 353 GLEEGDEVI---ISESTPGA 369
Cdd:PRK11556 367 GLSAGDRVVtdgIDRLTEGA 386
|
|
| PRK10476 |
PRK10476 |
multidrug transporter subunit MdtN; |
6-262 |
8.57e-17 |
|
multidrug transporter subunit MdtN;
Pssm-ID: 182488 [Multi-domain] Cd Length: 346 Bit Score: 80.46 E-value: 8.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 6 KRRKVWWLLALVVVIAAIWGWRILNAPLpqyqtlvarkSDlqqsvlaTGKLDAlRKVDVGAQVSGQLKTLRVNIGDKVQK 85
Cdd:PRK10476 11 KKLPALAIVALAIVALVFVIWRTDSAPS----------TD-------DAYIDA-DVVHVASEVGGRIVELAVTENQAVKK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 86 DQLLGVIDP-------EQAENQIKEVDATLMELR--------------AQLKQAQAERKLAQVTLARQQQLAQRQLVSRQ 144
Cdd:PRK10476 73 GDLLFRIDPrpyeltvAQAQADLALADAQIMTTQrsvdaersnaasanEQVERARANAKLATRTLERLEPLLAKGYVSAQ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 145 DLDTAAT-----DVAVKEAQ---------IGTI---EAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTLQGQTVIA 207
Cdd:PRK10476 153 QVDQARTaqrdaEVSLNQALlqaqaaaaaVGGVdalVAQRAAREAALAIAELHLEDTTVRAPFDGRVVGLKVSVGEFAAP 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 505180395 208 AQqapNILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDI 262
Cdd:PRK10476 233 MQ---PIFTLIDTDHWYAIANFRETDLKNIRVGDCATVYSMIDRGRPFEGKVDSI 284
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
45-294 |
2.55e-16 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 76.78 E-value: 2.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 45 DLQQSVLATGKL--DALRKVDVGAQVSGQLKTLRVN-IGDKVQKDQLLGVID-PEqaenqikevdatlmelraqLKQAQA 120
Cdd:pfam16576 1 PLSRTIRAVGRVayDERRLAHVHARVEGWIEKLYVNaTGDPVKKGQPLAELYsPE-------------------LVAAQQ 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 121 ERKLAqvtlarqqqLAQRQLVSRQDLDTAATD----VAVKEAQIgtieAQIKRNQatldTAKTNLDYTrilAPMSGEVTQ 196
Cdd:pfam16576 62 EYLLA---------LRSGDALSKSELLRAARQrlrlLGMPEAQI----AELERTG----KVQPTVTVY---APISGVVTE 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 197 ITTLQGQTVIAAQqapNILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAIfyY 276
Cdd:pfam16576 122 LNVREGMYVQPGD---TLFTIADLSTVWVEADVPEQDLALVKVGQPAEVTLPALPGKTFEGKVDYIYPTLDPKTRTV--R 196
|
250
....*....|....*...
gi 505180395 277 ARFEVPNPQGILRLEMTA 294
Cdd:pfam16576 197 VRIELPNPDGRLKPGMFA 214
|
|
| PRK03598 |
PRK03598 |
putative efflux pump membrane fusion protein; Provisional |
6-267 |
6.27e-15 |
|
putative efflux pump membrane fusion protein; Provisional
Pssm-ID: 235136 [Multi-domain] Cd Length: 331 Bit Score: 75.00 E-value: 6.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 6 KRRKVWWLLALVVVIAAIWGWRilnaplpQYQtlvarkSDLQQSVLATGKLDaLRKVDVGAQVSGQLKTLRVNIGDKVQK 85
Cdd:PRK03598 2 KKKVVIGLAVVVLAAAVAGGWW-------WYQ------SRQDNGLTLYGNVD-IRTVNLGFRVGGRLASLAVDEGDAVKA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 86 DQLLGVIDPE-------QAENQIKEVDATLMEL------------RAQLKQAQAERKLAQVTLARQQQLAQRQLVSRQDL 146
Cdd:PRK03598 68 GQVLGELDAApyenalmQAKANVSVAQAQLDLMlagyrdeeiaqaRAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 147 DTA--------ATDVAVKEA-----------QIGTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTLQGqTVIA 207
Cdd:PRK03598 148 ENArssrdqaqATLKSAQDKlsqyregnrpqDIAQAKASLAQAQAALAQAELNLQDTELIAPSDGTILTRAVEPG-TMLN 226
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 208 AQQApnILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPE 267
Cdd:PRK03598 227 AGST--VFTLSLTRPVWVRAYVDERNLGQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAE 284
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
46-235 |
2.77e-14 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 72.84 E-value: 2.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 46 LQQSVLATGKLDALRKVD-VGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEQAENQIKEVDATLMELRAQLKQAQAERKL 124
Cdd:pfam00529 4 LTKGVEAPGRVVVSGNAKaVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 125 AQVTlarqqqlaqrqlvsRQDLDTAATDVAVKEAQIGTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTLQGQT 204
Cdd:pfam00529 84 LQAL--------------ESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGAL 149
|
170 180 190
....*....|....*....|....*....|.
gi 505180395 205 VIAAQQAPNIlTLADLSTMLVKAQVSEADVI 235
Cdd:pfam00529 150 VAQAQANLLA-TVAQLDQIYVQITQSAAENQ 179
|
|
| PRK15030 |
PRK15030 |
multidrug efflux RND transporter periplasmic adaptor subunit AcrA; |
33-363 |
2.16e-13 |
|
multidrug efflux RND transporter periplasmic adaptor subunit AcrA;
Pssm-ID: 184990 [Multi-domain] Cd Length: 397 Bit Score: 70.90 E-value: 2.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 33 LPQYQTLVARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEQAEnqikevdATLMELR 112
Cdd:PRK15030 37 MPAVGVVTVKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ-------ATYDSAK 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 113 AQLKQAQAERKLAQVTLARQQQLAQRQLVSRQDLDTAATDvavkeAQIGTieAQIKRNQATLDTAKTNLDYTRILAPMSG 192
Cdd:PRK15030 110 GDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALAD-----AQQAN--AAVTAAKAAVETARINLAYTKVTSPISG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 193 EVTQITTLQGqTVIAAQQAPNILTLADLSTMLVKAQVSEADVIHLKP-----------GQKAWFTVLGDPLT-RYEGTLK 260
Cdd:PRK15030 183 RIGKSNVTEG-ALVQNGQATALATVQQLDPIYVDVTQSSNDFLRLKQelangtlkqenGKAKVSLITSDGIKfPQDGTLE 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 261 DILPTPEKVNDAIFYYARFevPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDAIGDNRYNVRLLRNGEVKEREIVI 340
Cdd:PRK15030 262 FSDVTVDQTTGSITLRAIF--PNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVETRPIVA 339
|
330 340
....*....|....*....|...
gi 505180395 341 GARNDTDVAVAKGLEEGDEVIIS 363
Cdd:PRK15030 340 SQAIGDKWLVTEGLKAGDRVVIS 362
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
63-363 |
2.33e-13 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 70.51 E-value: 2.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 63 DVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPeqaenqiKEVDATLMELRAQLKQAQAERKLAQVTLARQQQLAQRQLVS 142
Cdd:PRK09859 63 EIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDP-------APLQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVS 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 143 RQDLDTAATdvavkeaQIGTIEAQIKRNQATLDTAKTNLDYTRILAPMSGeVTQITTLQGQTVIAAQQAPNILTLADLST 222
Cdd:PRK09859 136 RQDYDTART-------QLNEAEANVTVAKAAVEQATINLQYANVTSPITG-VSGKSSVTVGALVTANQADSLVTVQRLDP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 223 MLVKAQVSEADVIHLK----PGQKAwfTVLGD-PLT-------RYE--GTLKDILPTPEKVNDAIFYYARFevPNPQGIL 288
Cdd:PRK09859 208 IYVDLTQSVQDFLRMKeevaSGQIK--QVQGStPVQlnlengkRYSqtGTLKFSDPTVDETTGSVTLRAIF--PNPNGDL 283
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180395 289 RLEMTAQVHIQLAEVKNVITIPLSALGDAIGDNRYNVRLLRNGEVKEREIVIGARNDTDVAVAKGLEEGDEVIIS 363
Cdd:PRK09859 284 LPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVS 358
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
185-291 |
4.03e-12 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 61.99 E-value: 4.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 185 RILAPMSGEVTQITTLQGQtVIAAQQapNILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILP 264
Cdd:pfam13437 1 TIRAPVDGVVAELNVEEGQ-VVQAGD--PLATIVPPDRLLVEAFVPAADLGSLKKGQKVTLKLDPGSDYTLEGKVVRISP 77
|
90 100
....*....|....*....|....*..
gi 505180395 265 TPEKVNDAIFYYARFEVPNPQGILRLE 291
Cdd:pfam13437 78 TVDPDTGVIPVRVSIENPKTPIPLLPG 104
|
|
| PRK09578 |
PRK09578 |
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit; |
30-363 |
5.88e-08 |
|
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 169982 [Multi-domain] Cd Length: 385 Bit Score: 54.03 E-value: 5.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 30 NAPLPQYQTLVARKSDLQQSVLATGKLDALRKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEQaenqikeVDATLM 109
Cdd:PRK09578 32 AAAPREATVVTVRPTSVPMTVELPGRLDAYRQAEVRARVAGIVTARTYEEGQEVKQGAVLFRIDPAP-------LKAARD 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 110 ELRAQLKQAQAERKLAQVTLARQQQLAQRQLVSRQDLDTAATDVAVKEAQIGTIEAQikrnqatLDTAKTNLDYTRILAP 189
Cdd:PRK09578 105 AAAGALAKAEAAHLAALDKRRRYDDLVRDRAVSERDYTEAVADERQAKAAVASAKAE-------LARAQLQLDYATVTAP 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 190 MSGEVTQITTLQGQTViaAQQAPNILTLAD-LSTMLVKAQVSEADVIHLKPGQKAW---------FTVlgdPLTRYEGT- 258
Cdd:PRK09578 178 IDGRARRALVTEGALV--GQDQATPLTTVEqLDPIYVNFSQPAADVEALRRAVKSGratgiaqqdVAV---TLVRADGSe 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 259 --------LKDILPTPEkvNDAIFYYARFevPNPQGILRLEMTAQVHIQLAEVKNVITIPLSALGDAIGdnRYNVRLL-R 329
Cdd:PRK09578 253 yplkgkllFSDLAVDPT--TDTVAMRALF--PNPERELLPGAYVRIALDRAVNPRAILVPRDALLRTAD--SASVKVVgQ 326
|
330 340 350
....*....|....*....|....*....|....
gi 505180395 330 NGEVKEREIVIGARNDTDVAVAKGLEEGDEVIIS 363
Cdd:PRK09578 327 NGKVRDVEVEADQMSGRDWIVTRGLAGGERVIVD 360
|
|
| PRK10559 |
PRK10559 |
p-hydroxybenzoic acid efflux pump subunit AaeA; |
62-249 |
9.73e-08 |
|
p-hydroxybenzoic acid efflux pump subunit AaeA;
Pssm-ID: 182548 [Multi-domain] Cd Length: 310 Bit Score: 52.82 E-value: 9.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 62 VDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDP---EQAENQiKEVDATLMELRAQLKQAQAERKLaqvtlarqqqLAQR 138
Cdd:PRK10559 48 VAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQpryQKALAE-AEADVAYYQVLAQEKRREAGRRN----------RLGV 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 139 QLVSRQDLDTAATDVAvkeaqigTIEAQIKRNQATLDTAKTNLDYTRILAPMSGEVTQITTLQGQTVIAAQQApniLTLA 218
Cdd:PRK10559 117 QAMSREEIDQANNVLQ-------TVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTA---VALV 186
|
170 180 190
....*....|....*....|....*....|.
gi 505180395 219 DLSTMLVKAQVSEADVIHLKPGQKAWFTVLG 249
Cdd:PRK10559 187 KQNSFYVLAYMEETKLEGVRPGYRAEITPLG 217
|
|
| Biotin_lipoyl_2 |
pfam13533 |
Biotin-lipoyl like; |
60-108 |
1.43e-03 |
|
Biotin-lipoyl like;
Pssm-ID: 433286 Cd Length: 50 Bit Score: 36.27 E-value: 1.43e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 505180395 60 RKVDVGAQVSGQLKTLRVNIGDKVQKDQLLGVIDPEQAENQIKEVDATL 108
Cdd:pfam13533 1 PVVKIASPVSGKVVAVNVKEGQQVKKGDVLATLDSPELQLQLQQAEAQL 49
|
|
| type_I_hlyD |
TIGR01843 |
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport ... |
95-298 |
3.37e-03 |
|
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 130902 [Multi-domain] Cd Length: 423 Bit Score: 39.22 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 95 EQAENQIKEVDATLMELRAQLKQAQAERKLAQVTLARQQQLAQRQLVSRQDL-------DTAATDVAVKEAQIGTIEAQI 167
Cdd:TIGR01843 147 ELILAQIKQLEAELAGLQAQLQALRQQLEVISEELEARRKLKEKGLVSRLELlelererAEAQGELGRLEAELEVLKRQI 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 168 --------------------KRNQATLDTAKTNLDYTR---------ILAPMSGEVTQIT-TLQGQTVIAAQQAPNILTL 217
Cdd:TIGR01843 227 delqlerqqieqtfreevleELTEAQARLAELRERLNKardrlqrliIRSPVDGTVQSLKvHTVGGVVQPGETLMEIVPE 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 218 ADlsTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRY---EGTLKDILP--TPEKVNDAIFYYARFEVPN---PQGILR 289
Cdd:TIGR01843 307 DD--PLEIEAKLSPKDIGFVHVGQPAEIKFSAFPYRRYgilNGKVKSISPdtFTDERGGGPYYRVRISIDQntlGIGPKG 384
|
250
....*....|...
gi 505180395 290 LE----MTAQVHI 298
Cdd:TIGR01843 385 LElspgMPVTADI 397
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
90-188 |
3.67e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 39.06 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 90 GVIDPE-QAENQIKevdaTLMELRAQLKQAQAERKLAqvtlarqqqlaqrqlvsRQDLDTAATDVAVKEAQIGTIEAQIK 168
Cdd:COG3524 208 GILDPEaTAEALLQ----LIATLEGQLAELEAELAAL-----------------RSYLSPNSPQVRQLRRRIAALEKQIA 266
|
90 100
....*....|....*....|
gi 505180395 169 RNQATLDTAKTNLDYTRILA 188
Cdd:COG3524 267 AERARLTGASGGDSLASLLA 286
|
|
| PRK15136 |
PRK15136 |
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA; |
4-250 |
7.98e-03 |
|
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA;
Pssm-ID: 185090 [Multi-domain] Cd Length: 390 Bit Score: 38.14 E-value: 7.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 4 NGKRRKVWWLLALVVVIAAIwGWRIlnaplpqYQTLVARKSDLQQSVLATGKldalrKVDVGAQVSGQLKTLRVNIGDKV 83
Cdd:PRK15136 17 KGKRKRALLLLTLLFIIIGV-AYGI-------YWFLVLRHHQETDDAYVAGN-----QVQIMSQVSGSVTKVWADNTDFV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 84 QKDQLLGVIDP---EQAENQIKEVDATLMELRAQL----KQAQAERKLAQVTLARQQQLA-------QRQLVSRQDLDTA 149
Cdd:PRK15136 84 KEGDVLVTLDPtdaEQAFEKAKTALANSVRQTHQLminsKQYQANIELQKTALAQAQSDLnrrvplgNANLIGREELQHA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180395 150 ATDVAVKEAQIGTIEAQIKRNQAT-LDT-----------------AKTNLDYTRILAPMSGEVTQiTTLQgqtvIAAQQA 211
Cdd:PRK15136 164 RDAVASAQAQLDVAIQQYNANQAMiLNTpledqpavqqaatevrnAWLALQRTKIVSPMTGYVSR-RSVQ----VGAQIS 238
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 505180395 212 PN--ILTLADLSTMLVKAQVSEADVIHLKPGQKAwfTVLGD 250
Cdd:PRK15136 239 PTtpLMAVVPATNLWVDANFKETQLANMRIGQPA--TITSD 277
|
|
| |
