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Concise Results
Standard Results
Full Results
MULTISPECIES: lysine decarboxylase CadA [Klebsiella]
Protein Classification
lysine decarboxylase CadA ( domain architecture ID 11487771 )
lysine decarboxylase CadA catalyzes the conversion from L-lysine to cadaverine; plays a role in pH homeostasis by consuming protons and neutralizing the acidic by-products of carbohydrate fermentation
List of domain hits
Name
Accession
Description
Interval
E-value
PRK15400
PRK15400 lysine decarboxylase;
1-712
0e+00
lysine decarboxylase;
Pssm-ID: 185298 [Multi-domain]
Cd Length: 714
Bit Score: 1540.57
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 1 MNVIAI M NHMGVYFKEEPIRELHRALERL D F R IVYPNDRDDLLKLIENN S RLCGVIFDWDKYNLELCEEISKMNE YM PLY 80
Cdd:PRK15400 1 MNVIAI L NHMGVYFKEEPIRELHRALERL N F Q IVYPNDRDDLLKLIENN A RLCGVIFDWDKYNLELCEEISKMNE NL PLY 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 81 AFANTYSTLDVSLNDLR M QV R FFEYALGAA E DIANKIKQ N TDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK 160
Cdd:PRK15400 81 AFANTYSTLDVSLNDLR L QV S FFEYALGAA D DIANKIKQ T TDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 161 SPVGS I FYDFFG S NTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNA E RSYMVTNGTSTANKIVGMYSAPAGSTVLI 240
Cdd:PRK15400 161 SPVGS L FYDFFG P NTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNA D RSYMVTNGTSTANKIVGMYSAPAGSTVLI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 241 DRNCHKSLTHLMMMSD I TPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK 320
Cdd:PRK15400 241 DRNCHKSLTHLMMMSD V TPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 321 TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS 400
Cdd:PRK15400 321 TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 401 PHYGIVASTETAAAMM R GNAGKRLI D GSIER S IKFRKEIKRL KG ES E GWFFDVWQP E HID GA ECWPLRSDS A WHGFKNID 480
Cdd:PRK15400 401 PHYGIVASTETAAAMM K GNAGKRLI N GSIER A IKFRKEIKRL RT ES D GWFFDVWQP D HID TT ECWPLRSDS T WHGFKNID 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 481 NEHMYLDPIKVTLLTPGMKKDGTM D DFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF 560
Cdd:PRK15400 481 NEHMYLDPIKVTLLTPGMKKDGTM S DFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 561 DLNLRVKNMLPSLYREDPEFYENMRIQ D LAQNIHKL VE HHNLPDLM F RAFEVLP S MVMTPYAAFQKELHG Q TEEVYL E EM 640
Cdd:PRK15400 561 DLNLRVKNMLPSLYREDPEFYENMRIQ E LAQNIHKL IV HHNLPDLM Y RAFEVLP T MVMTPYAAFQKELHG M TEEVYL D EM 640
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180756 641 VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEE 712
Cdd:PRK15400 641 VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEE 712
Name
Accession
Description
Interval
E-value
PRK15400
PRK15400 lysine decarboxylase;
1-712
0e+00
lysine decarboxylase;
Pssm-ID: 185298 [Multi-domain]
Cd Length: 714
Bit Score: 1540.57
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 1 MNVIAI M NHMGVYFKEEPIRELHRALERL D F R IVYPNDRDDLLKLIENN S RLCGVIFDWDKYNLELCEEISKMNE YM PLY 80
Cdd:PRK15400 1 MNVIAI L NHMGVYFKEEPIRELHRALERL N F Q IVYPNDRDDLLKLIENN A RLCGVIFDWDKYNLELCEEISKMNE NL PLY 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 81 AFANTYSTLDVSLNDLR M QV R FFEYALGAA E DIANKIKQ N TDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK 160
Cdd:PRK15400 81 AFANTYSTLDVSLNDLR L QV S FFEYALGAA D DIANKIKQ T TDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 161 SPVGS I FYDFFG S NTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNA E RSYMVTNGTSTANKIVGMYSAPAGSTVLI 240
Cdd:PRK15400 161 SPVGS L FYDFFG P NTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNA D RSYMVTNGTSTANKIVGMYSAPAGSTVLI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 241 DRNCHKSLTHLMMMSD I TPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK 320
Cdd:PRK15400 241 DRNCHKSLTHLMMMSD V TPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 321 TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS 400
Cdd:PRK15400 321 TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 401 PHYGIVASTETAAAMM R GNAGKRLI D GSIER S IKFRKEIKRL KG ES E GWFFDVWQP E HID GA ECWPLRSDS A WHGFKNID 480
Cdd:PRK15400 401 PHYGIVASTETAAAMM K GNAGKRLI N GSIER A IKFRKEIKRL RT ES D GWFFDVWQP D HID TT ECWPLRSDS T WHGFKNID 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 481 NEHMYLDPIKVTLLTPGMKKDGTM D DFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF 560
Cdd:PRK15400 481 NEHMYLDPIKVTLLTPGMKKDGTM S DFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 561 DLNLRVKNMLPSLYREDPEFYENMRIQ D LAQNIHKL VE HHNLPDLM F RAFEVLP S MVMTPYAAFQKELHG Q TEEVYL E EM 640
Cdd:PRK15400 561 DLNLRVKNMLPSLYREDPEFYENMRIQ E LAQNIHKL IV HHNLPDLM Y RAFEVLP T MVMTPYAAFQKELHG M TEEVYL D EM 640
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180756 641 VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEE 712
Cdd:PRK15400 641 VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEE 712
OKR_DC_1
pfam01276 Orn/Lys/Arg decarboxylase, major domain;
130-545
0e+00
Orn/Lys/Arg decarboxylase, major domain;
Pssm-ID: 396025 [Multi-domain]
Cd Length: 417
Bit Score: 698.49
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 130 PPL T KALFKYVR E G K YTF CT PGH M GG TA FQK S P V G SI FYDFFG S N TMKS D IS I SVS ELG S LLDH S G PH KEA EE Y I ARVF N 209
Cdd:pfam01276 1 PPL Y KALFKYVR R G N YTF HC PGH Q GG AG FQK H P A G RF FYDFFG E N LLRI D VC I EDV ELG D LLDH E G AI KEA QK Y A ARVF G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 210 A ER SY M V T NGTS TA NK I VGM YSAPA G S T V LIDRNCHKS LT H LM M M S DI TP I Y FR P T RNAYGI L GGIP QS EFQ HA T IAKRV 289
Cdd:pfam01276 81 A DK SY F V V NGTS GS NK T VGM AVCTP G D T I LIDRNCHKS IH H AL M L S GA TP V Y LE P S RNAYGI I GGIP LH EFQ EE T LKEAI 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 290 K E T P N A TW P VH AVITN S TYDG L LYN TDF I KK TL DVK S -- I H FDSAWV P Y TN F S PIY EGKCG M S G GRVE G KV I YE TQS T HK 367
Cdd:pfam01276 161 A E V P D A KG P RL AVITN P TYDG V LYN AKE I VD TL HHL S dp I L FDSAWV G Y EQ F I PIY ADASP M G G ENEN G PG I FV TQS V HK 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 368 LLAA F SQAS M IH V K GD -- VN EET FNEA Y MMH T TTSP H Y G I V AS TET AA A M MR GN A G K RL IDGSI ER S I K FRK E I KR L kge 445
Cdd:pfam01276 241 LLAA L SQAS Y IH K K EG hi VN HDR FNEA F MMH A TTSP S Y P I F AS LDV AA K M LE GN S G R RL WNECV ER A I E FRK A I DT L --- 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 446 SEGW FF DV W Q PE HI DG A ECWP LRSDSA WHGF KNIDNEHMY LDP I K V T L LTPGM KK DG TMDD FG I PA S IVAK Y L D E H GIV V 525
Cdd:pfam01276 318 NNCE FF RP W N PE IV DG K ECWP FHPGET WHGF EGYADNQYF LDP C K L T I LTPGM DE DG EYSE FG V PA T IVAK W L R E N GIV P 397
410 420
....*....|....*....|
gi 505180756 526 EKT GPY N L LFLF SI G I D K TK 545
Cdd:pfam01276 398 EKT DLN N I LFLF TP G E D R TK 417
LdcC
COG1982 Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
124-711
0e+00
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
Pssm-ID: 441585 [Multi-domain]
Cd Length: 486
Bit Score: 581.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 124 Y I D TI L P PL TK AL F KY VRE G KYT F CT PGH M GG TA F qkspv G SI FYDFFG S N TMKS D ISI s VSE L GS L L D HS G PH KEA E E Y 203
Cdd:COG1982 1 Y M D QL L T PL FD AL K KY AER G PVS F HV PGH K GG RG F ----- G RE FYDFFG E N VFRL D LTE - LPG L DD L H D PE G VI KEA Q E L 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 204 I A RV F N A E R SYMVT NGTS TA NK IVGMYSAPA G ST VL ID RNCHKS LT H LMMM S DIT P I Y FR P T - R N AY GI L GGI PQSEFQH 282
Cdd:COG1982 75 A A EA F G A D R TFFLV NGTS SG NK AMILAVCGP G DK VL VP RNCHKS VI H GLIL S GAI P V Y LN P E i D N EL GI I GGI TPEAVEE 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 283 A tiakr VK E T P N A twp VHAV ITN S TY D G LL Y NTDF I KKTLD -- VKSIHF D S A WVPYTN F S P IYE g KCG M SG G rvegk VIY 360
Cdd:COG1982 155 A ----- LI E H P D A --- KAVL ITN P TY Y G VC Y DLKA I AELAH eh GIPVLV D E A HGAHFG F H P DLP - RSA M EA G ----- ADL 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 361 ET QSTHK L L A A FS Q A SM I HVKG D - V NE E TF NEA Y M MHTT TSP H Y GIV AS TET A AAM M R G N a G KR L I D GSI E RS I KF RKEI 439
Cdd:COG1982 221 VV QSTHK T L G A LT Q S SM L HVKG G r V DH E RV NEA L M LLQS TSP S Y LLM AS LDV A RRQ M A G E - G EE L L D EAL E LA I EA RKEI 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 440 KRL kgeseg WFFD V WQ PE HIDGAEC wplrsdsawhgfknidneh MY LDP I K V T LLT PG M kkdgtmddf GI PASI VA K YL D 519
Cdd:COG1982 300 NKI ------ PGLY V FG PE DLGAPGV ------------------- YD LDP T K L T IDV PG L --------- GI SGYE VA E YL R 345
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 520 E H - GI V VE KTGP YN L LFL F S I G ID K TKALS L LR AL TDF KR AF D L N LRVKNM LP slyredpefyenmriqdlaqnihklve 598
Cdd:COG1982 346 E E y GI Q VE LADL YN I LFL L S L G DT K EDIER L VA AL KEL KR LY D K N APLEEV LP --------------------------- 398
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 599 hhnlpdlmf R AF EV LP SM VM T P YA AF Q kelh GQ TE E V Y LEE M VGR VN A N M IL PYPPG V PL V MPGE M ITEE srp V LEF L QM 678
Cdd:COG1982 399 --------- L AF PP LP EL VM S P RE AF F ---- AE TE L V P LEE A VGR IA A E M VI PYPPG I PL L MPGE R ITEE --- V IDY L RA 462
570 580 590
....*....|....*....|....*....|...
gi 505180756 679 L C E I G AHY PGFE T dihgayrqa DGRY T VK V L KE 711
Cdd:COG1982 463 L E E A G GRF PGFE D --------- PELR T IR V V KE 486
Orn_deC_like
cd00615 Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
131-441
3.93e-122
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain]
Cd Length: 294
Bit Score: 366.19
E-value: 3.93e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 131 PL TK AL FK Y VRE G KYT F CT PGH M GG TA F Q KS pvgsi FY D F F G S N TM K S D ISI s VSE L GS LLD HS GP H KEA E E YI AR V F N A 210
Cdd:cd00615 1 PL FE AL KE Y AKR G IIS F HV PGH K GG RG F R KS ----- FY E F Y G E N LF K A D VTE - LTG L DD LLD PT GP I KEA Q E LA AR A F G A 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 211 ERSYMVT NGTS TA NK I V GMYSAPA G STV LIDRNCHKS LTHLMMM S DIT P I Y FR P T RN A Y - GI L GGIP QSE F QH A T I AKR v 289
Cdd:cd00615 75 KHTFFLV NGTS SS NK A V ILAVCGP G DKI LIDRNCHKS VINGLVL S GAV P V Y LK P E RN P Y y GI A GGIP PET F KK A L I EHP - 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 290 ketpnat WPVH AVITN S TY D G LL YN TDF I KKTLD -- VKSIHF D S A WVPYTN F S PI YEGKCG M S G G rvegkv IYET QSTHK 367
Cdd:cd00615 154 ------- DAKA AVITN P TY Y G IC YN LRK I VEEAH hr GLPVLV D E A HGAHFR F H PI LPSSAA M A G A ------ DIVV QSTHK 220
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180756 368 L L A A FS Q A SMIHVKGD - VN EETF NEA YMM H TT TSP H Y G I V AS TET A A AMM r GNA GK R L IDGS IE RSIKF R K EI KR 441
Cdd:cd00615 221 T L P A LT Q G SMIHVKGD l VN PDRV NEA LNL H QS TSP S Y L I L AS LDV A R AMM - ALE GK E L VEEL IE LALYA R Q EI NK 294
Name
Accession
Description
Interval
E-value
PRK15400
PRK15400 lysine decarboxylase;
1-712
0e+00
lysine decarboxylase;
Pssm-ID: 185298 [Multi-domain]
Cd Length: 714
Bit Score: 1540.57
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 1 MNVIAI M NHMGVYFKEEPIRELHRALERL D F R IVYPNDRDDLLKLIENN S RLCGVIFDWDKYNLELCEEISKMNE YM PLY 80
Cdd:PRK15400 1 MNVIAI L NHMGVYFKEEPIRELHRALERL N F Q IVYPNDRDDLLKLIENN A RLCGVIFDWDKYNLELCEEISKMNE NL PLY 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 81 AFANTYSTLDVSLNDLR M QV R FFEYALGAA E DIANKIKQ N TDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK 160
Cdd:PRK15400 81 AFANTYSTLDVSLNDLR L QV S FFEYALGAA D DIANKIKQ T TDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 161 SPVGS I FYDFFG S NTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNA E RSYMVTNGTSTANKIVGMYSAPAGSTVLI 240
Cdd:PRK15400 161 SPVGS L FYDFFG P NTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNA D RSYMVTNGTSTANKIVGMYSAPAGSTVLI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 241 DRNCHKSLTHLMMMSD I TPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK 320
Cdd:PRK15400 241 DRNCHKSLTHLMMMSD V TPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 321 TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS 400
Cdd:PRK15400 321 TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 401 PHYGIVASTETAAAMM R GNAGKRLI D GSIER S IKFRKEIKRL KG ES E GWFFDVWQP E HID GA ECWPLRSDS A WHGFKNID 480
Cdd:PRK15400 401 PHYGIVASTETAAAMM K GNAGKRLI N GSIER A IKFRKEIKRL RT ES D GWFFDVWQP D HID TT ECWPLRSDS T WHGFKNID 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 481 NEHMYLDPIKVTLLTPGMKKDGTM D DFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF 560
Cdd:PRK15400 481 NEHMYLDPIKVTLLTPGMKKDGTM S DFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 561 DLNLRVKNMLPSLYREDPEFYENMRIQ D LAQNIHKL VE HHNLPDLM F RAFEVLP S MVMTPYAAFQKELHG Q TEEVYL E EM 640
Cdd:PRK15400 561 DLNLRVKNMLPSLYREDPEFYENMRIQ E LAQNIHKL IV HHNLPDLM Y RAFEVLP T MVMTPYAAFQKELHG M TEEVYL D EM 640
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505180756 641 VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEE 712
Cdd:PRK15400 641 VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEE 712
PRK15399
PRK15399 lysine decarboxylase;
1-710
0e+00
lysine decarboxylase;
Pssm-ID: 185297 [Multi-domain]
Cd Length: 713
Bit Score: 1422.59
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 1 MN V IAIM NHM GV YF K E EPI R EL HR AL ERLD F RIVY P NDRD DLLK L IE N N S R L CGVIFDWD K Y N L E LC EE I SKM NEY M PLY 80
Cdd:PRK15399 1 MN I IAIM GPH GV FY K D EPI K EL ES AL QAQG F QTIW P QNSV DLLK F IE H N P R I CGVIFDWD E Y S L D LC SD I NQL NEY L PLY 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 81 AF A NT Y ST L DVS LN D L RM QVR FFEYALGAAEDIA NK I K Q N T D EY I D T I L PP L TKALF K YV R EGKYTFCTPGHMGGTA F QK 160
Cdd:PRK15399 81 AF I NT H ST M DVS VQ D M RM ALW FFEYALGAAEDIA IR I R Q Y T N EY L D N I T PP F TKALF T YV K EGKYTFCTPGHMGGTA Y QK 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 161 SPVG SI FYDFFG S NT M K S D I SISV S ELGSLLDH S GPH K EAEEYIAR V F N AE R SY M VTNGTST A NKIVGMY S APAGST V LI 240
Cdd:PRK15399 161 SPVG CL FYDFFG G NT L K A D V SISV T ELGSLLDH T GPH L EAEEYIAR T F G AE Q SY I VTNGTST S NKIVGMY A APAGST L LI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 241 DRNCHKSL T HL M MMSD IT PI YFR PTRNA Y GILGGIP QS EF QHAT I AKR V KE T PN A T WPVHAVITNSTYDGLLYNTD F IK K 320
Cdd:PRK15399 241 DRNCHKSL A HL L MMSD VV PI WLK PTRNA L GILGGIP RR EF TRDS I EEK V AA T TQ A Q WPVHAVITNSTYDGLLYNTD W IK Q 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 321 TLDV K SIHFDSAWVPYT N F S PIY E GK C GMSG G RV E GKVI Y ETQSTHK L LAAFSQAS M IH V KG DVN EETFNEA Y MMHT T TS 400
Cdd:PRK15399 321 TLDV P SIHFDSAWVPYT H F H PIY Q GK S GMSG E RV P GKVI F ETQSTHK M LAAFSQAS L IH I KG EYD EETFNEA F MMHT S TS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 401 P H Y G IVAS T ETAAAM M RGN A GKRLI DG S I ER SIK FRKE IK RL KG ES E GWFFD V WQPE HI D G AECWP LRSDSA WHGFK NI D 480
Cdd:PRK15399 401 P S Y P IVAS V ETAAAM L RGN P GKRLI NR S V ER ALH FRKE VQ RL RE ES D GWFFD I WQPE NV D E AECWP VAPGEQ WHGFK DA D 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 481 NE HM Y LDP I KVT L LTPGM KKD G T M DDF GIPA SI VAK Y LDE H GIVVEKTGPYNLLFLFSIGIDKTKA LS LLR A LT D FKRA F 560
Cdd:PRK15399 481 AD HM F LDP V KVT I LTPGM DEQ G N M SEE GIPA AL VAK F LDE R GIVVEKTGPYNLLFLFSIGIDKTKA MG LLR G LT E FKRA Y 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 561 DLNLRVKNMLP S LY R EDP E FY E NMRIQDLAQ N IHKL VEH H N LP D LM F RAF E VLP S M V MTP YA A F Q KELH G QT E E V Y LE EM 640
Cdd:PRK15399 561 DLNLRVKNMLP D LY A EDP D FY R NMRIQDLAQ G IHKL IRK H D LP G LM L RAF D VLP E M I MTP HQ A W Q RQIK G EV E T V A LE QL 640
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 641 VGRV N ANMILPYPPGVPL V MPGEMITEESR P VL E FL Q MLC E IG A HYPGFETDIHGA Y R QA DG R Y T V K VLK 710
Cdd:PRK15399 641 VGRV S ANMILPYPPGVPL L MPGEMITEESR A VL D FL L MLC S IG Q HYPGFETDIHGA K R DE DG V Y R V R VLK 710
OKR_DC_1
pfam01276 Orn/Lys/Arg decarboxylase, major domain;
130-545
0e+00
Orn/Lys/Arg decarboxylase, major domain;
Pssm-ID: 396025 [Multi-domain]
Cd Length: 417
Bit Score: 698.49
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 130 PPL T KALFKYVR E G K YTF CT PGH M GG TA FQK S P V G SI FYDFFG S N TMKS D IS I SVS ELG S LLDH S G PH KEA EE Y I ARVF N 209
Cdd:pfam01276 1 PPL Y KALFKYVR R G N YTF HC PGH Q GG AG FQK H P A G RF FYDFFG E N LLRI D VC I EDV ELG D LLDH E G AI KEA QK Y A ARVF G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 210 A ER SY M V T NGTS TA NK I VGM YSAPA G S T V LIDRNCHKS LT H LM M M S DI TP I Y FR P T RNAYGI L GGIP QS EFQ HA T IAKRV 289
Cdd:pfam01276 81 A DK SY F V V NGTS GS NK T VGM AVCTP G D T I LIDRNCHKS IH H AL M L S GA TP V Y LE P S RNAYGI I GGIP LH EFQ EE T LKEAI 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 290 K E T P N A TW P VH AVITN S TYDG L LYN TDF I KK TL DVK S -- I H FDSAWV P Y TN F S PIY EGKCG M S G GRVE G KV I YE TQS T HK 367
Cdd:pfam01276 161 A E V P D A KG P RL AVITN P TYDG V LYN AKE I VD TL HHL S dp I L FDSAWV G Y EQ F I PIY ADASP M G G ENEN G PG I FV TQS V HK 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 368 LLAA F SQAS M IH V K GD -- VN EET FNEA Y MMH T TTSP H Y G I V AS TET AA A M MR GN A G K RL IDGSI ER S I K FRK E I KR L kge 445
Cdd:pfam01276 241 LLAA L SQAS Y IH K K EG hi VN HDR FNEA F MMH A TTSP S Y P I F AS LDV AA K M LE GN S G R RL WNECV ER A I E FRK A I DT L --- 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 446 SEGW FF DV W Q PE HI DG A ECWP LRSDSA WHGF KNIDNEHMY LDP I K V T L LTPGM KK DG TMDD FG I PA S IVAK Y L D E H GIV V 525
Cdd:pfam01276 318 NNCE FF RP W N PE IV DG K ECWP FHPGET WHGF EGYADNQYF LDP C K L T I LTPGM DE DG EYSE FG V PA T IVAK W L R E N GIV P 397
410 420
....*....|....*....|
gi 505180756 526 EKT GPY N L LFLF SI G I D K TK 545
Cdd:pfam01276 398 EKT DLN N I LFLF TP G E D R TK 417
LdcC
COG1982 Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
124-711
0e+00
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
Pssm-ID: 441585 [Multi-domain]
Cd Length: 486
Bit Score: 581.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 124 Y I D TI L P PL TK AL F KY VRE G KYT F CT PGH M GG TA F qkspv G SI FYDFFG S N TMKS D ISI s VSE L GS L L D HS G PH KEA E E Y 203
Cdd:COG1982 1 Y M D QL L T PL FD AL K KY AER G PVS F HV PGH K GG RG F ----- G RE FYDFFG E N VFRL D LTE - LPG L DD L H D PE G VI KEA Q E L 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 204 I A RV F N A E R SYMVT NGTS TA NK IVGMYSAPA G ST VL ID RNCHKS LT H LMMM S DIT P I Y FR P T - R N AY GI L GGI PQSEFQH 282
Cdd:COG1982 75 A A EA F G A D R TFFLV NGTS SG NK AMILAVCGP G DK VL VP RNCHKS VI H GLIL S GAI P V Y LN P E i D N EL GI I GGI TPEAVEE 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 283 A tiakr VK E T P N A twp VHAV ITN S TY D G LL Y NTDF I KKTLD -- VKSIHF D S A WVPYTN F S P IYE g KCG M SG G rvegk VIY 360
Cdd:COG1982 155 A ----- LI E H P D A --- KAVL ITN P TY Y G VC Y DLKA I AELAH eh GIPVLV D E A HGAHFG F H P DLP - RSA M EA G ----- ADL 220
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 361 ET QSTHK L L A A FS Q A SM I HVKG D - V NE E TF NEA Y M MHTT TSP H Y GIV AS TET A AAM M R G N a G KR L I D GSI E RS I KF RKEI 439
Cdd:COG1982 221 VV QSTHK T L G A LT Q S SM L HVKG G r V DH E RV NEA L M LLQS TSP S Y LLM AS LDV A RRQ M A G E - G EE L L D EAL E LA I EA RKEI 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 440 KRL kgeseg WFFD V WQ PE HIDGAEC wplrsdsawhgfknidneh MY LDP I K V T LLT PG M kkdgtmddf GI PASI VA K YL D 519
Cdd:COG1982 300 NKI ------ PGLY V FG PE DLGAPGV ------------------- YD LDP T K L T IDV PG L --------- GI SGYE VA E YL R 345
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 520 E H - GI V VE KTGP YN L LFL F S I G ID K TKALS L LR AL TDF KR AF D L N LRVKNM LP slyredpefyenmriqdlaqnihklve 598
Cdd:COG1982 346 E E y GI Q VE LADL YN I LFL L S L G DT K EDIER L VA AL KEL KR LY D K N APLEEV LP --------------------------- 398
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 599 hhnlpdlmf R AF EV LP SM VM T P YA AF Q kelh GQ TE E V Y LEE M VGR VN A N M IL PYPPG V PL V MPGE M ITEE srp V LEF L QM 678
Cdd:COG1982 399 --------- L AF PP LP EL VM S P RE AF F ---- AE TE L V P LEE A VGR IA A E M VI PYPPG I PL L MPGE R ITEE --- V IDY L RA 462
570 580 590
....*....|....*....|....*....|...
gi 505180756 679 L C E I G AHY PGFE T dihgayrqa DGRY T VK V L KE 711
Cdd:COG1982 463 L E E A G GRF PGFE D --------- PELR T IR V V KE 486
PRK15029
PRK15029 arginine decarboxylase; Provisional
16-710
0e+00
arginine decarboxylase; Provisional
Pssm-ID: 184989 [Multi-domain]
Cd Length: 755
Bit Score: 565.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 16 EEPIRE L HR AL ERLDFRIVYPNDR DD LLKLIEN N SRLCGVI F DWDKYNLELCEEISKM ------- NEYM P LYAFANTYST 88
Cdd:PRK15029 18 GNAVER L AD AL SQQNVTVIKSTSF DD GFAILSS N EAIDCLM F SYQMEHPDEHQNVRQL igklher QQNV P VFLLGDREKA 97
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 89 L DVSLN DL RMQ V RF F EYA L GAAE D - IA NKIKQNTDE Y IDTI LPPL TK AL F KY VREGK Y TFCT PGH M GG TA F Q K S P V G SIF 167
Cdd:PRK15029 98 L AAMDR DL LEL V DE F AWI L EDTA D f IA GRAVAAMTR Y RQQL LPPL FS AL M KY SDIHE Y SWAA PGH Q GG VG F T K T P A G RFY 177
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 168 Y D FF G S N TMKS D IS I SVSE LGSLLDH S G PHK E A E E Y I ARVF N A E RS YM V TN GTS TA N KIVGMYSAPAGST V LI DRNCHKS 247
Cdd:PRK15029 178 H D YY G E N LFRT D MG I ERTS LGSLLDH T G AFG E S E K Y A ARVF G A D RS WS V VV GTS GS N RTIMQACMTDNDV V VV DRNCHKS 257
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 248 LTHLMMMSDIT P I Y FR P T RN A YGI L G G I PQS E F Q HA T IA K RVK E T P NA ----- TW P VHA V I TN S TYDG LL YN TDFIKKT L 322
Cdd:PRK15029 258 IEQGLILTGAK P V Y MV P S RN R YGI I G P I YPQ E M Q PE T LQ K KIS E S P LT kdkag QK P SYC V V TN C TYDG VC YN AKEAQDL L 337
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 323 DVK S -- I HFD S AW VP Y TN F S PIY EGKCG M S G -- G RVE G KVIYE T Q STHKLL A A F SQAS M IHV --- K G DV N EET FN E AYMM 395
Cdd:PRK15029 338 EKT S dr L HFD E AW YG Y AR F N PIY ADHYA M R G ep G DHN G PTVFA T H STHKLL N A L SQAS Y IHV reg R G AI N FSR FN Q AYMM 417
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 396 H T TTSP H Y G I V AS TET A AA MM R GN A G KR L IDGS I ERSIK FR KEIK RL K --- GESEG WFF DV W QP E --------- HI D G A E 463
Cdd:PRK15029 418 H A TTSP L Y A I C AS NDV A VS MM D GN S G LS L TQEV I DEAVD FR QAMA RL Y kef TADGS WFF KP W NK E vvtdpqtgk TY D F A D 497
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 464 ----------- CW PLRSDSA WHGFK NIDNEHMY LDPIKV TL L T PGM KK DG TMDDF G I PA SI V AKY L DE HGIV VEK T GPYN 532
Cdd:PRK15029 498 aptkllttvqd CW VMHPGES WHGFK DLPDNWSM LDPIKV SI L A PGM GE DG ELEET G V PA AL V TAW L GR HGIV PTR T TDFQ 577
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 533 LL FLFS I G IDKT K ALS L LRA L TD FKR AF D L N LRVKNML P S L YRED P EF Y E NM R I Q DL AQNIHKLVEHH N LPDLMFR A FEV 612
Cdd:PRK15029 578 IM FLFS M G VTRG K WGT L VNT L CS FKR HY D A N TPLAQVM P E L VEQY P DT Y A NM G I H DL GDTMFAWLKEN N PGARLNE A YSG 657
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 613 LP SMVM TP YA A FQKELHGQT E E V YL E EMV GR VN AN MIL PYPPG V P LVMP GE MITEESR P VLEF L QM L CEIGA H Y PGFE TD 692
Cdd:PRK15029 658 LP VAEI TP RE A YNAIVDNNV E L V SI E NLP GR IA AN SVI PYPPG I P MLLS GE NFGDKNS P QVSY L RS L QSWDH H F PGFE HE 737
730
....*....|....*...
gi 505180756 693 IH G A y RQA DG R Y T V KVL K 710
Cdd:PRK15029 738 TE G T - EII DG I Y H V MCV K 754
PRK13578
PRK13578 ornithine decarboxylase; Provisional
103-711
4.33e-128
ornithine decarboxylase; Provisional
Pssm-ID: 237434 [Multi-domain]
Cd Length: 720
Bit Score: 396.64
E-value: 4.33e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 103 FE YALGAA E DIANKIKQNTDE Y IDTI LPP LTKA L FK YV RE G KY TF CT PGH M GG TA F Q K S P V G SI FYDFFG S N TMKS D ISI 182
Cdd:PRK13578 82 FE LCESNN E FYGRQLETAASK Y EENL LPP FFDT L TD YV EM G NS TF DC PGH Q GG QF F R K H P A G RQ FYDFFG E N LFRA D MCN 161
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 183 SVSE LG S LL D H S G PH K E A EEYI A R VFNA ERS Y M V T NGTS TA NK I V GMYSAPA G ST VL I DRN C HKS LT H - LMMMSDI TP I Y 261
Cdd:PRK13578 162 ADVK LG D LL I H E G AA K D A QKHA A K VFNA DKT Y F V L NGTS AS NK V V TNALLTP G DL VL F DRN N HKS NH H g ALIQAGA TP V Y 241
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 262 FRPT RN AY G IL GGI PQSE F QHATIAKRVK E T ---- PNATW P VH - AVI TNS TYDG LL YN T ---- D F I KKTL D V ks I H FDSA 332
Cdd:PRK13578 242 LETA RN PF G FI GGI DAHC F DEEYLREQIR E V aper ADEAR P FR l AVI QLG TYDG TI YN A rqvv D K I GHLC D Y -- I L FDSA 319
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 333 WV P Y TN F S P IYE g K C gm S GGRV E ------ G kv I YE TQS T HK LL A A FSQ A S M IH ----- V KG D --- VNEETF N E A Y M M H TT 398
Cdd:PRK13578 320 WV G Y EQ F I P MMA - D C -- S PLLL E lnendp G -- I FV TQS V HK QQ A G FSQ T S Q IH kkdnh I KG Q ary CPHKRL N N A F M L H AS 394
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 399 TSP H Y GIV A STETA A A M MR G NA G K RL IDGSIERS I KF RK E I - K R L K gesegw FFDVWQ P EHI DG A -- ECW P ------- LR 468
Cdd:PRK13578 395 TSP F Y PLF A ALDVN A K M HE G ES G R RL WMECVKLG I EA RK L I l A R C K ------ LIRPFI P PVV DG K pw QDY P teqiasd LR 468
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 469 ----- SDSA WHGF KNIDNEHMYL DP I K VT L L TPG MK - KD G TMD DFGIPA S I V A K YL D E H GIV V EK TGPYNL LFL FSIGI D 542
Cdd:PRK13578 469 ffsfe PGEK WHGF EGYAEDQYFV DP C K LL L T TPG ID a ET G EYE DFGIPA T I L A N YL R E N GIV P EK CDLNSI LFL LTPAE D 548
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 543 KT K ALS L LRA L TD F KRAFDLNLRVKNM LPS L Y RED PE F Y ENMRIQD L A Q NI H K L VEH H NLPD L --- MFR A f EVL P SM VM T 619
Cdd:PRK13578 549 MA K LQQ L VAM L AR F EKHIEDDAPLAEV LPS V Y KKN PE R Y RGYTLRQ L C Q EM H D L YVS H DVKQ L qke MFR K - ASF P RV VM N 627
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 620 P YA A FQKELH G QT E E V Y L E E MV GR VN A NMI LPYPPGV PL V M PGE MITE esr P V LEFLQM L C E IGAHY PGF ETDIH G A Y -- 697
Cdd:PRK13578 628 P QD A NIAYIR G EV E L V R L S E AE GR IA A EGA LPYPPGV LC V V PGE IWGG --- A V QRYFLA L E E GINLL PGF APELQ G V Y le 704
650
....*....|....*.
gi 505180756 698 RQ ADGR YTVK -- VLK E 711
Cdd:PRK13578 705 TD ADGR KRAY gy VLK P 720
Orn_deC_like
cd00615 Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
131-441
3.93e-122
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain]
Cd Length: 294
Bit Score: 366.19
E-value: 3.93e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 131 PL TK AL FK Y VRE G KYT F CT PGH M GG TA F Q KS pvgsi FY D F F G S N TM K S D ISI s VSE L GS LLD HS GP H KEA E E YI AR V F N A 210
Cdd:cd00615 1 PL FE AL KE Y AKR G IIS F HV PGH K GG RG F R KS ----- FY E F Y G E N LF K A D VTE - LTG L DD LLD PT GP I KEA Q E LA AR A F G A 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 211 ERSYMVT NGTS TA NK I V GMYSAPA G STV LIDRNCHKS LTHLMMM S DIT P I Y FR P T RN A Y - GI L GGIP QSE F QH A T I AKR v 289
Cdd:cd00615 75 KHTFFLV NGTS SS NK A V ILAVCGP G DKI LIDRNCHKS VINGLVL S GAV P V Y LK P E RN P Y y GI A GGIP PET F KK A L I EHP - 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 290 ketpnat WPVH AVITN S TY D G LL YN TDF I KKTLD -- VKSIHF D S A WVPYTN F S PI YEGKCG M S G G rvegkv IYET QSTHK 367
Cdd:cd00615 154 ------- DAKA AVITN P TY Y G IC YN LRK I VEEAH hr GLPVLV D E A HGAHFR F H PI LPSSAA M A G A ------ DIVV QSTHK 220
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 505180756 368 L L A A FS Q A SMIHVKGD - VN EETF NEA YMM H TT TSP H Y G I V AS TET A A AMM r GNA GK R L IDGS IE RSIKF R K EI KR 441
Cdd:cd00615 221 T L P A LT Q G SMIHVKGD l VN PDRV NEA LNL H QS TSP S Y L I L AS LDV A R AMM - ALE GK E L VEEL IE LALYA R Q EI NK 294
OKR_DC_1_C
pfam03711 Orn/Lys/Arg decarboxylase, C-terminal domain;
570-701
5.91e-67
Orn/Lys/Arg decarboxylase, C-terminal domain;
Pssm-ID: 461020 [Multi-domain]
Cd Length: 132
Bit Score: 216.62
E-value: 5.91e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 570 LP S L YRED PE F YE N M RIQ DL A Q NI H KLVEHH N LPD L MFR AF EV LP SMV MTP YA A F Q KELH G QT E E V Y L E E MV GR VN A NMI 649
Cdd:pfam03711 1 LP E L VAAY PE R YE G M GLR DL C Q EM H DFYREN N VAR L QKE AF RS LP EPA MTP AE A Y Q ELVR G EV E L V P L D E LE GR IA A VGV 80
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 505180756 650 LPYPPG V PL V MPGE MIT EE S RP V L EF L QM L C E IGAHY PGFET D IHG A YR QA D 701
Cdd:pfam03711 81 LPYPPG I PL L MPGE RFG EE N RP I L DY L LA L E E FDNRF PGFET E IHG V YR EE D 132
OKR_DC_1_N
pfam03709 Orn/Lys/Arg decarboxylase, N-terminal domain; This domain has a flavodoxin-like fold, and is ...
14-124
1.51e-35
Orn/Lys/Arg decarboxylase, N-terminal domain; This domain has a flavodoxin-like fold, and is termed the "wing" domain because of its position in the overall 3D structure.
Pssm-ID: 427454 [Multi-domain]
Cd Length: 111
Bit Score: 130.05
E-value: 1.51e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 14 F K EEPI REL HR ALER LDFRI V YPNDR DDLL KL IE NNSRLCG V IFD WD K Y NLE L CE EI SKM N EYM P LYAFAN T YSTL DV SL 93
Cdd:pfam03709 1 L K IAAS REL AE ALER TGREV V DATST DDLL AA IE TFTDIAA V VLS WD D Y AAG L LD EI RRR N FDL P VFLLGE T HTSE DV PA 80
90 100 110
....*....|....*....|....*....|.
gi 505180756 94 ND LR MQVR F F E Y A LGAA E D IA NK I KQNTDE Y 124
Cdd:pfam03709 81 DV LR LIDG F I E L A EDTP E F IA RQ I EAAAKK Y 111
AAT_I
cd01494 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
196-381
6.08e-06
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain]
Cd Length: 170
Bit Score: 46.99
E-value: 6.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 196 PHK E A EE YI AR VFNAERSYM V - TNGTST AN KIVGMYSAPA G ST V LI D R N C H K S lt HLMMMSDI --- T P IYFRPTRNA YG I 271
Cdd:cd01494 1 KLE E L EE KL AR LLQPGNDKA V f VPSGTG AN EAALLALLGP G DE V IV D A N G H G S -- RYWVAAEL aga K P VPVPVDDAG YG G 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505180756 272 L ggipqsefq HAT I AKRV K ET PN atw PVHA VIT NS T YD G LLY ---- NTDF I K K TLDVK s IHF D S A WVPY tnfspiyegkc 347
Cdd:cd01494 79 L --------- DVA I LEEL K AK PN --- VALI VIT PN T TS G GVL vplk EIRK I A K EYGIL - LLV D A A SAGG ----------- 134
170 180 190
....*....|....*....|....*....|....*..
gi 505180756 348 GMSGGR V EGKVIYE --- T Q S T HK L L AA f SQASMIH VK 381
Cdd:cd01494 135 ASPAPG V LIPEGGA dvv T F S L HK N L GG - EGGGVVI VK 170
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
