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Conserved domains on  [gi|505181275|ref|WP_015368377|]
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MULTISPECIES: YtjB family periplasmic protein [Klebsiella]

Protein Classification

YtjB family periplasmic protein( domain architecture ID 10013769)

YtjB/Smp family periplasmic protein similar to Salmonella enterica protein YtjB/Smp and Pasteurella multocida protein AhpA that affects hemolysin expression

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK11246 PRK11246
YtjB family periplasmic protein;
1-210 9.18e-145

YtjB family periplasmic protein;


:

Pssm-ID: 236885  Cd Length: 218  Bit Score: 401.76  E-value: 9.18e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETPDEKRITRLLEQ 80
Cdd:PRK11246   1 MARAKLKFRLHRTAIVLICLALLVALMQGASWFSQSHQRARNPQLEELARTLARQVALSLAPLMRSDSPDEKRIQAILDQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275  81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:PRK11246  81 LTDESRILDASVYDEQGDLIARSGESVNVRDRLALDGKKAGSYFNQQIVEPIAGKNGPLGFLRLTLDTHTLATEAKQVDN 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505181275 161 TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTANKPVQDEDKD 210
Cdd:PRK11246 161 TTNILRLMLLLALAIGIVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEES 210
 
Name Accession Description Interval E-value
PRK11246 PRK11246
YtjB family periplasmic protein;
1-210 9.18e-145

YtjB family periplasmic protein;


Pssm-ID: 236885  Cd Length: 218  Bit Score: 401.76  E-value: 9.18e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETPDEKRITRLLEQ 80
Cdd:PRK11246   1 MARAKLKFRLHRTAIVLICLALLVALMQGASWFSQSHQRARNPQLEELARTLARQVALSLAPLMRSDSPDEKRIQAILDQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275  81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:PRK11246  81 LTDESRILDASVYDEQGDLIARSGESVNVRDRLALDGKKAGSYFNQQIVEPIAGKNGPLGFLRLTLDTHTLATEAKQVDN 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505181275 161 TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTANKPVQDEDKD 210
Cdd:PRK11246 161 TTNILRLMLLLALAIGIVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEES 210
AhpA COG3726
Uncharacterized membrane protein Smp affecting hemolysin expression [Function unknown];
1-210 2.43e-94

Uncharacterized membrane protein Smp affecting hemolysin expression [Function unknown];


Pssm-ID: 442940  Cd Length: 208  Bit Score: 273.72  E-value: 2.43e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETPDEkRITRLLEQ 80
Cdd:COG3726    2 MIKAKLKKRLHRTLIVLICLALLVILLQGASYFSLGSQLALSNQVENLARLLVRQAAFSASPLLVNNDKNE-RLTALLNQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275  81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:COG3726   81 LTKESRILDASVYDADGELLAQSGEALSVRDRLGLDGPLAGSYFRQQIVEPIFGKDGPLGFLRVTLDTHVLATEQHQVDN 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505181275 161 TTNILRLMLLLSLAIGVVLTRTLLQGKRTRwqQSPFLLTANKPVQDEDKD 210
Cdd:COG3726  161 TTNLLRLMLLLALLIGILLARTLLRFRRTR--QSPFLLTASKPVKEEDEK 208
SMP_2 pfam10144
Bacterial virulence factor haemolysin; Members of this family of bacterial proteins are ...
1-160 1.49e-80

Bacterial virulence factor haemolysin; Members of this family of bacterial proteins are membrane proteins that effect the expression of haemolysin under anaerobic conditions.


Pssm-ID: 431085  Cd Length: 159  Bit Score: 237.21  E-value: 1.49e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275    1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETpDEKRITRLLEQ 80
Cdd:pfam10144   1 MARAKLKFRLHRTVIILICLALLVVLLQGASYFSLGHQLARSNQVEELAHLLVRQVAFSLSPLLVDNA-DNERITAILDQ 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:pfam10144  80 LTKESRILDASVYDNDGTLVAHSGEALSVRDRLGLDGPRAGSYFNQQIVEPIFGKDGPIGFLRVTLDTHYLATEAKQVDN 159
 
Name Accession Description Interval E-value
PRK11246 PRK11246
YtjB family periplasmic protein;
1-210 9.18e-145

YtjB family periplasmic protein;


Pssm-ID: 236885  Cd Length: 218  Bit Score: 401.76  E-value: 9.18e-145
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETPDEKRITRLLEQ 80
Cdd:PRK11246   1 MARAKLKFRLHRTAIVLICLALLVALMQGASWFSQSHQRARNPQLEELARTLARQVALSLAPLMRSDSPDEKRIQAILDQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275  81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:PRK11246  81 LTDESRILDASVYDEQGDLIARSGESVNVRDRLALDGKKAGSYFNQQIVEPIAGKNGPLGFLRLTLDTHTLATEAKQVDN 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505181275 161 TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTANKPVQDEDKD 210
Cdd:PRK11246 161 TTNILRLMLLLALAIGIVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEES 210
PRK14061 PRK14061
unknown domain/lipoate-protein ligase A fusion protein; Provisional
1-209 7.01e-127

unknown domain/lipoate-protein ligase A fusion protein; Provisional


Pssm-ID: 172552 [Multi-domain]  Cd Length: 562  Bit Score: 369.05  E-value: 7.01e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETPDEKRITRLLEQ 80
Cdd:PRK14061   1 MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQLEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275  81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:PRK14061  81 LTDESRILDAGVYDEQGDLIARSGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 505181275 161 TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTANKPVQDEDK 209
Cdd:PRK14061 161 TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEE 209
AhpA COG3726
Uncharacterized membrane protein Smp affecting hemolysin expression [Function unknown];
1-210 2.43e-94

Uncharacterized membrane protein Smp affecting hemolysin expression [Function unknown];


Pssm-ID: 442940  Cd Length: 208  Bit Score: 273.72  E-value: 2.43e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETPDEkRITRLLEQ 80
Cdd:COG3726    2 MIKAKLKKRLHRTLIVLICLALLVILLQGASYFSLGSQLALSNQVENLARLLVRQAAFSASPLLVNNDKNE-RLTALLNQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275  81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:COG3726   81 LTKESRILDASVYDADGELLAQSGEALSVRDRLGLDGPLAGSYFRQQIVEPIFGKDGPLGFLRVTLDTHVLATEQHQVDN 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505181275 161 TTNILRLMLLLSLAIGVVLTRTLLQGKRTRwqQSPFLLTANKPVQDEDKD 210
Cdd:COG3726  161 TTNLLRLMLLLALLIGILLARTLLRFRRTR--QSPFLLTASKPVKEEDEK 208
SMP_2 pfam10144
Bacterial virulence factor haemolysin; Members of this family of bacterial proteins are ...
1-160 1.49e-80

Bacterial virulence factor haemolysin; Members of this family of bacterial proteins are membrane proteins that effect the expression of haemolysin under anaerobic conditions.


Pssm-ID: 431085  Cd Length: 159  Bit Score: 237.21  E-value: 1.49e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275    1 MVRAKLKFRLHRAVIVLICLALLVALMQGASWFSQNSQKQRNPQLEELARTLAQQVTLNLAPLMRSETpDEKRITRLLEQ 80
Cdd:pfam10144   1 MARAKLKFRLHRTVIILICLALLVVLLQGASYFSLGHQLARSNQVEELAHLLVRQVAFSLSPLLVDNA-DNERITAILDQ 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   81 LTDKSRVLDAGVYDEQGDLVARSGESVDVRDRLALDGKKAGGYFNQQIVEPILGKNGPVGYLRLTLDTHTLATEAKQVDN 160
Cdd:pfam10144  80 LTKESRILDASVYDNDGTLVAHSGEALSVRDRLGLDGPRAGSYFNQQIVEPIFGKDGPIGFLRVTLDTHYLATEAKQVDN 159
CHASE8 pfam17152
Periplasmic sensor domain; CHASE8 is a conserved periplasmic sensor domain found in histidine ...
40-145 1.38e-03

Periplasmic sensor domain; CHASE8 is a conserved periplasmic sensor domain found in histidine kinases, diguanylate cyclases/phosphodiesterases and methyl-accepting chemotaxis proteins, including the diguanylate cyclase DgcN (YfiN) that regulates biofilm formation and motility in Escherichia coli. In Pseudomonas aeruginosa, CHASE8 is the sensor domain in the diguanylate cyclase TpbB that regulates biofilm formation by controlling the levels of extracellular DNA.


Pssm-ID: 435752  Cd Length: 102  Bit Score: 36.85  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505181275   40 QRNpqLEELARTLAQQVTlnlAPLMRSetpDEKRITRLLEQLTDKSRVLDAGVYDEQGDLVAR-SGESVDVRDRLALdgK 118
Cdd:pfam17152   6 QQN--LELLARSIAYNVE---AALVFG---DPAAARETLAALGAQPQIASAAVYDAQGRLFASyARPGTDPPEPLEA--L 75
                          90       100
                  ....*....|....*....|....*..
gi 505181275  119 KAGGYFNQQIVEPILGKNGPVGYLRLT 145
Cdd:pfam17152  76 LARWLLPAPVLQPIVHDGERIGSVVLA 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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