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Conserved domains on  [gi|505182112|ref|WP_015369214|]
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MULTISPECIES: HTH-type transcriptional regulator [Klebsiella]

Protein Classification

transcriptional regulator( domain architecture ID 10793339)

helix-turn-helix-type transcriptional regulator

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10072 PRK10072
HTH-type transcriptional regulator;
1-96 7.10e-55

HTH-type transcriptional regulator;


:

Pssm-ID: 182222  Cd Length: 96  Bit Score: 164.96  E-value: 7.10e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182112  1 MEYKDPVFDLLSNLEQIVFKDQPQTATHARTPSVFNEFERLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKL 80
Cdd:PRK10072  1 MEYKDPMFELLSSLEQIVFKDETQKITLTQKTTSFTEFEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKL 80

                        90
                ....*....|....*.
gi 505182112 81 MRLMMANPQLSRQLID 96
Cdd:PRK10072 81 MRLIQANPALSKQLME 96
 
Name Accession Description Interval E-value
PRK10072 PRK10072
HTH-type transcriptional regulator;
1-96 7.10e-55

HTH-type transcriptional regulator;


Pssm-ID: 182222  Cd Length: 96  Bit Score: 164.96  E-value: 7.10e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182112  1 MEYKDPVFDLLSNLEQIVFKDQPQTATHARTPSVFNEFERLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKL 80
Cdd:PRK10072  1 MEYKDPMFELLSSLEQIVFKDETQKITLTQKTTSFTEFEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKL 80

                        90
                ....*....|....*.
gi 505182112 81 MRLMMANPQLSRQLID 96
Cdd:PRK10072 81 MRLIQANPALSKQLME 96
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
37-90 3.39e-14

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 61.10  E-value: 3.39e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 505182112 37 EFERLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLMRLMMANPQL 90
Cdd:COG2944  10 EIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAALKLLRLLEKHPEL 63
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 40-81 1.22e-04

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 36.76  E-value: 1.22e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 505182112 40 RLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLM 81
Cdd:cd00093   6 ELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKL 47
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
40-81 1.97e-04

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 35.96  E-value: 1.97e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 505182112   40 RLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLM 81
Cdd:smart00530  4 ELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKL 45
NadS NF041265
NadS family protein;
51-94 1.01e-03

NadS family protein;


Pssm-ID: 469165  Cd Length: 94  Bit Score: 35.15  E-value: 1.01e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 505182112 51 DFANAMGVSVAMVEEWESRRVKPSSTELKLMRLMMANPQLSRQL 94
Cdd:NF041265 48 EMAKALGTSVDTIKSWESKRRNPTGLAAKVLATIQDNPAFFKEL 91
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 37-94 1.62e-03

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 34.91  E-value: 1.62e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 505182112   37 EFERLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLMRLMMANPQLSRQL 94
Cdd:TIGR03830  69 EIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSKALDKLLRLLDKHPELLEEL 126
 
Name Accession Description Interval E-value
PRK10072 PRK10072
HTH-type transcriptional regulator;
1-96 7.10e-55

HTH-type transcriptional regulator;


Pssm-ID: 182222  Cd Length: 96  Bit Score: 164.96  E-value: 7.10e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182112  1 MEYKDPVFDLLSNLEQIVFKDQPQTATHARTPSVFNEFERLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKL 80
Cdd:PRK10072  1 MEYKDPMFELLSSLEQIVFKDETQKITLTQKTTSFTEFEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKL 80

                        90
                ....*....|....*.
gi 505182112 81 MRLMMANPQLSRQLID 96
Cdd:PRK10072 81 MRLIQANPALSKQLME 96
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
37-90 3.39e-14

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 61.10  E-value: 3.39e-14
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 505182112 37 EFERLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLMRLMMANPQL 90
Cdd:COG2944  10 EIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAALKLLRLLEKHPEL 63
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 40-81 1.22e-04

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 36.76  E-value: 1.22e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 505182112 40 RLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLM 81
Cdd:cd00093   6 ELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKL 47
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
40-81 1.97e-04

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 35.96  E-value: 1.97e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 505182112   40 RLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLM 81
Cdd:smart00530  4 ELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKL 45
NadS NF041265
NadS family protein;
51-94 1.01e-03

NadS family protein;


Pssm-ID: 469165  Cd Length: 94  Bit Score: 35.15  E-value: 1.01e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 505182112 51 DFANAMGVSVAMVEEWESRRVKPSSTELKLMRLMMANPQLSRQL 94
Cdd:NF041265 48 EMAKALGTSVDTIKSWESKRRNPTGLAAKVLATIQDNPAFFKEL 91
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
40-79 1.57e-03

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 34.20  E-value: 1.57e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|
gi 505182112 40 RLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELK 79
Cdd:COG1396  14 ELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLL 53
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 37-94 1.62e-03

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 34.91  E-value: 1.62e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 505182112   37 EFERLRKGTGLKTDDFANAMGVSVAMVEEWESRRVKPSSTELKLMRLMMANPQLSRQL 94
Cdd:TIGR03830  69 EIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSKALDKLLRLLDKHPELLEEL 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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