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Conserved domains on  [gi|505182980|ref|WP_015370082|]
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MULTISPECIES: L-alanine exporter AlaE [Klebsiella]

Protein Classification

L-alanine exporter AlaE( domain architecture ID 10535124)

L-alanine exporter AlaE is a multi-pass membrane protein that exports L-alanine

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AlaE pfam06610
L-alanine exporter; AlaE is a family of Gram-negative amino-acid transporters. It is not ...
 3-141 1.04e-66

L-alanine exporter; AlaE is a family of Gram-negative amino-acid transporters. It is not entirely clear why bacteria export metabolites but recent studies have shown that many excrete alanine. AlaE is likely to be the exporter protein for L-alanine. UniProtKB:A8ANM6, UniProt:G4R961 and UniProt:H5SVY7 are classified as putative alanine exporters.


:

Pssm-ID: 399538  Cd Length: 141  Bit Score: 198.80  E-value: 1.04e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182980    3 SAQSRLRHAVADTFAMVVYCTVVNMMIEIFLSGMTFEQSLSSRLVAIPVNIIIAVPYGFYRDFAMRQARRISTSG-WMKN 81
Cdd:pfam06610   1 SANSRLRSAAADTFAMVVFCFIVGMAIEILISGMTFEQSLASRLLSIPVNILIAWPYGLYRDWFLRLGKRTSPASrWMKN 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182980   82 IADVVAYVTFQSPVYVLILLSVGADWHQIAAAVSSNILVSMMMGAVYGYFLDFCRRLFRV 141
Cdd:pfam06610  81 LADLLAYVSFQSPVYAAILLAVGASFAQIITAVASNAVLSMVLGVPYGYFLEYCRRLFRV 140
 
Name Accession Description Interval E-value
AlaE pfam06610
L-alanine exporter; AlaE is a family of Gram-negative amino-acid transporters. It is not ...
 3-141 1.04e-66

L-alanine exporter; AlaE is a family of Gram-negative amino-acid transporters. It is not entirely clear why bacteria export metabolites but recent studies have shown that many excrete alanine. AlaE is likely to be the exporter protein for L-alanine. UniProtKB:A8ANM6, UniProt:G4R961 and UniProt:H5SVY7 are classified as putative alanine exporters.


Pssm-ID: 399538  Cd Length: 141  Bit Score: 198.80  E-value: 1.04e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182980    3 SAQSRLRHAVADTFAMVVYCTVVNMMIEIFLSGMTFEQSLSSRLVAIPVNIIIAVPYGFYRDFAMRQARRISTSG-WMKN 81
Cdd:pfam06610   1 SANSRLRSAAADTFAMVVFCFIVGMAIEILISGMTFEQSLASRLLSIPVNILIAWPYGLYRDWFLRLGKRTSPASrWMKN 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182980   82 IADVVAYVTFQSPVYVLILLSVGADWHQIAAAVSSNILVSMMMGAVYGYFLDFCRRLFRV 141
Cdd:pfam06610  81 LADLLAYVSFQSPVYAAILLAVGASFAQIITAVASNAVLSMVLGVPYGYFLEYCRRLFRV 140
 
Name Accession Description Interval E-value
AlaE pfam06610
L-alanine exporter; AlaE is a family of Gram-negative amino-acid transporters. It is not ...
 3-141 1.04e-66

L-alanine exporter; AlaE is a family of Gram-negative amino-acid transporters. It is not entirely clear why bacteria export metabolites but recent studies have shown that many excrete alanine. AlaE is likely to be the exporter protein for L-alanine. UniProtKB:A8ANM6, UniProt:G4R961 and UniProt:H5SVY7 are classified as putative alanine exporters.


Pssm-ID: 399538  Cd Length: 141  Bit Score: 198.80  E-value: 1.04e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182980    3 SAQSRLRHAVADTFAMVVYCTVVNMMIEIFLSGMTFEQSLSSRLVAIPVNIIIAVPYGFYRDFAMRQARRISTSG-WMKN 81
Cdd:pfam06610   1 SANSRLRSAAADTFAMVVFCFIVGMAIEILISGMTFEQSLASRLLSIPVNILIAWPYGLYRDWFLRLGKRTSPASrWMKN 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 505182980   82 IADVVAYVTFQSPVYVLILLSVGADWHQIAAAVSSNILVSMMMGAVYGYFLDFCRRLFRV 141
Cdd:pfam06610  81 LADLLAYVSFQSPVYAAILLAVGASFAQIITAVASNAVLSMVLGVPYGYFLEYCRRLFRV 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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