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Conserved domains on  [gi|505200084|ref|WP_015387186|]
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MULTISPECIES: DUF305 domain-containing protein [Enterobacteriaceae]

Protein Classification

DUF305 domain-containing protein( domain architecture ID 10007543)

DUF305 domain-containing protein similar to Synechocystis sp. CopM, a protein that binds copper and contributes to copper resistance in Synechocystis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3544 COG3544
Uncharacterized conserved protein, DUF305 family [Function unknown];
43-115 6.91e-24

Uncharacterized conserved protein, DUF305 family [Function unknown];


:

Pssm-ID: 442765  Cd Length: 75  Bit Score: 86.88  E-value: 6.91e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505200084  43 MKDMHDKMMAAVNEPDPDKAFAKGMVAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSH 115
Cdd:COG3544    1 MIPHHQQAVEMASGADFDRLFLQLMIAHHQGAIDMAQAELEHGKDPEVRELAQDIIAAQTAEIAQMRALLAAL 73
 
Name Accession Description Interval E-value
COG3544 COG3544
Uncharacterized conserved protein, DUF305 family [Function unknown];
43-115 6.91e-24

Uncharacterized conserved protein, DUF305 family [Function unknown];


Pssm-ID: 442765  Cd Length: 75  Bit Score: 86.88  E-value: 6.91e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505200084  43 MKDMHDKMMAAVNEPDPDKAFAKGMVAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSH 115
Cdd:COG3544    1 MIPHHQQAVEMASGADFDRLFLQLMIAHHQGAIDMAQAELEHGKDPEVRELAQDIIAAQTAEIAQMRALLAAL 73
DUF305 pfam03713
Domain of unknown function (DUF305); Domain found in small family of bacterial secreted ...
 14-112 2.58e-21

Domain of unknown function (DUF305); Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.


Pssm-ID: 427457 [Multi-domain]  Cd Length: 151  Bit Score: 82.75  E-value: 2.58e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505200084   14 SLPAISAEHSEMNMSDMTSSAssqeyMAGM-KDMHDKMMAAVNEPDPDKAFAKGMVAHHEGAIAMAETELKYGKDPEMRK 92
Cdd:pfam03713  57 GGPPSSAGGHAHGGGGAEGAG-----MPGMaSPADLAALRAATGADFDRLFLELMIPHHQGAVEMAQDELDRGTDPEVRA 131

                          90       100
                  ....*....|....*....|
gi 505200084   93 LAQDIIKAQKGEIEQMNKWL 112
Cdd:pfam03713 132 LAQDIIESQQAEIAQMRQLL 151
prfA PRK00591
peptide chain release factor 1; Validated
 75-108 1.00e-02

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 34.28  E-value: 1.00e-02
                         10        20        30
                 ....*....|....*....|....*....|....
gi 505200084  75 IAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQM 108
Cdd:PRK00591  61 LEEAKEMLEEESDPEMREMAKEELKELEERLEEL 94
 
Name Accession Description Interval E-value
COG3544 COG3544
Uncharacterized conserved protein, DUF305 family [Function unknown];
43-115 6.91e-24

Uncharacterized conserved protein, DUF305 family [Function unknown];


Pssm-ID: 442765  Cd Length: 75  Bit Score: 86.88  E-value: 6.91e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505200084  43 MKDMHDKMMAAVNEPDPDKAFAKGMVAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSH 115
Cdd:COG3544    1 MIPHHQQAVEMASGADFDRLFLQLMIAHHQGAIDMAQAELEHGKDPEVRELAQDIIAAQTAEIAQMRALLAAL 73
DUF305 pfam03713
Domain of unknown function (DUF305); Domain found in small family of bacterial secreted ...
 14-112 2.58e-21

Domain of unknown function (DUF305); Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.


Pssm-ID: 427457 [Multi-domain]  Cd Length: 151  Bit Score: 82.75  E-value: 2.58e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505200084   14 SLPAISAEHSEMNMSDMTSSAssqeyMAGM-KDMHDKMMAAVNEPDPDKAFAKGMVAHHEGAIAMAETELKYGKDPEMRK 92
Cdd:pfam03713  57 GGPPSSAGGHAHGGGGAEGAG-----MPGMaSPADLAALRAATGADFDRLFLELMIPHHQGAVEMAQDELDRGTDPEVRA 131

                          90       100
                  ....*....|....*....|
gi 505200084   93 LAQDIIKAQKGEIEQMNKWL 112
Cdd:pfam03713 132 LAQDIIESQQAEIAQMRQLL 151
DUF305 pfam03713
Domain of unknown function (DUF305); Domain found in small family of bacterial secreted ...
 60-115 5.12e-17

Domain of unknown function (DUF305); Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.


Pssm-ID: 427457 [Multi-domain]  Cd Length: 151  Bit Score: 71.58  E-value: 5.12e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 505200084   60 DKAFAKGMVAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSH 115
Cdd:pfam03713   1 DVGFAQDMIPHHQQAVEMAELALERAQDPEVRALAQDIIAAQQPEIGQMRGWLEAW 56
COG3652 COG3652
Predicted outer membrane protein, contains DUF4142 domain [Function unknown];
36-114 5.44e-05

Predicted outer membrane protein, contains DUF4142 domain [Function unknown];


Pssm-ID: 442869  Cd Length: 176  Bit Score: 40.31  E-value: 5.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505200084  36 SQEYMAGMKDMHDKMmAAVNEPDPDKAFAKGMVAHHEGAIAMAETELKYGKDPEMRKLAQD---IIKAQKGEIEQMNKWL 112
Cdd:COG3652   96 PTELSADQQAKLDKL-SKLSGAAFDKAYVDQQVAAHEKAVALFEKYAAPGKDAELKAFAQKtlpTLQAHLEMAEALAKKL 174


                 ..
gi 505200084 113 DS 114
Cdd:COG3652  175 GK 176
DUF4142 pfam13628
Domain of unknown function (DUF4142); This is a bacterial family of unknown function.
 34-96 4.69e-04

Domain of unknown function (DUF4142); This is a bacterial family of unknown function.


Pssm-ID: 433361  Cd Length: 138  Bit Score: 37.21  E-value: 4.69e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505200084   34 ASSQEYMAGMKDMHDKMmAAVNEPDPDKAFAKGMVAHHEGAIAMAETELKYGKDPEMRKLAQD 96
Cdd:pfam13628  62 LPDTTLDADQQAKLDKL-SALSGAAFDKAYLDQQVAAHQKAVELFEKYAASGDDPELKAFAAK 123
prfA PRK00591
peptide chain release factor 1; Validated
 75-108 1.00e-02

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 34.28  E-value: 1.00e-02
                         10        20        30
                 ....*....|....*....|....*....|....
gi 505200084  75 IAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQM 108
Cdd:PRK00591  61 LEEAKEMLEEESDPEMREMAKEELKELEERLEEL 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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