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Conserved domains on  [gi|505462511|ref|WP_015649466|]
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MULTISPECIES: transporter [Pseudomonas]

Protein Classification

transporter( domain architecture ID 10611654)

transporter forming an outer membrane channel that adopts a 12-stranded beta-barrel structure, similar to Pseudomonas aeruginosa SphA (formerly PA5325), which may function as an uptake channel for sphingosine

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Phenol_MetA_deg pfam13557
Putative MetA-pathway of phenol degradation;
68-294 3.40e-24

Putative MetA-pathway of phenol degradation;


:

Pssm-ID: 463920  Cd Length: 237  Bit Score: 97.94  E-value: 3.40e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511   68 NGKAELKTNAVAYRQVFFSDICGTLCTPQFIIPFVDIDARLPGSAGHTG---ETGFGDPQVGGTLFFINDPERRRYSGLL 144
Cdd:pfam13557  15 GGDLQVEAGLPRFVYVTDTTLGGASLGRYGLLPFGWLDLKLDGGGPGAYsdsRSGLGDLTLGPKILGWEDKGGNPHVALY 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511  145 TLITLPLGEYHAKNPdVSPGTNRWGATFVYNYTQGIGRDWVLEANLEAQFYAKNDDYfgsDLEQKPLYRLQAFASYDFsq 224
Cdd:pfam13557  95 LGVNLPTGDYDKNAL-ANPGLNYWSFSPTLALTYQLGPGWELSANLGYDFNGENDDT---DYQSGQEFHLDFALGYAV-- 168
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505462511  225 sTYGALKLvhADGGELKLQGHTLDDTHQRYTQLGFELGHWLDRRNSLMF--GLSRNVATDNAFHGSQALLRL 294
Cdd:pfam13557 169 -TNGKWSV--GLVGYYYKSGGGADGDRGRVFALGPGLAYLFTPNLQLDAsaGKGLEFAARNRFEGAGLSLRF 237
 
Name Accession Description Interval E-value
Phenol_MetA_deg pfam13557
Putative MetA-pathway of phenol degradation;
68-294 3.40e-24

Putative MetA-pathway of phenol degradation;


Pssm-ID: 463920  Cd Length: 237  Bit Score: 97.94  E-value: 3.40e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511   68 NGKAELKTNAVAYRQVFFSDICGTLCTPQFIIPFVDIDARLPGSAGHTG---ETGFGDPQVGGTLFFINDPERRRYSGLL 144
Cdd:pfam13557  15 GGDLQVEAGLPRFVYVTDTTLGGASLGRYGLLPFGWLDLKLDGGGPGAYsdsRSGLGDLTLGPKILGWEDKGGNPHVALY 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511  145 TLITLPLGEYHAKNPdVSPGTNRWGATFVYNYTQGIGRDWVLEANLEAQFYAKNDDYfgsDLEQKPLYRLQAFASYDFsq 224
Cdd:pfam13557  95 LGVNLPTGDYDKNAL-ANPGLNYWSFSPTLALTYQLGPGWELSANLGYDFNGENDDT---DYQSGQEFHLDFALGYAV-- 168
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505462511  225 sTYGALKLvhADGGELKLQGHTLDDTHQRYTQLGFELGHWLDRRNSLMF--GLSRNVATDNAFHGSQALLRL 294
Cdd:pfam13557 169 -TNGKWSV--GLVGYYYKSGGGADGDRGRVFALGPGLAYLFTPNLQLDAsaGKGLEFAARNRFEGAGLSLRF 237
SphA COG4313
Sphingosine uptake channel SphA-related outer membrane channel [Cell wall/membrane/envelope ...
96-298 1.96e-10

Sphingosine uptake channel SphA-related outer membrane channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443454  Cd Length: 303  Bit Score: 60.33  E-value: 1.96e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511  96 QFIIPFVDIDARLPGSAGHTGETGFGDPQVGGtlFFINDPERRRYSGLLTL-ITLPLGEYHAKNPdVSPGTNRWGATFVY 174
Cdd:COG4313  104 SAIVPLVSLDVDANVGGVSDSRTGLGDIYLGP--LILGWHPSPNLHVVAGLdIYAPTGSYDPNRL-ANPGLNYWTFDPTL 180
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511 175 NYTQGIGRDWVLEANLEAQFYAKNDDyfgSDLEQKPLYRLQAFASYDFSQS-----TYGALKLVHADggelKLQGHTLDD 249
Cdd:COG4313  181 AFTYLFDDGWELSAKLGYDFNTKNPD---TDYQSGQEFHLDYALGKHFGKGwrlglVGYYYKQLTDD----SGPGARLDG 253
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505462511 250 THQRYTQLGFELGHWLDRRN-SLMFGLSRNVATDNAFHGSQALLRLVHVF 298
Cdd:COG4313  254 FRGRVFALGPGVGYDFPPGGfSLSLKWYHEFGARNRPEGDALWLRLSIPF 303
 
Name Accession Description Interval E-value
Phenol_MetA_deg pfam13557
Putative MetA-pathway of phenol degradation;
68-294 3.40e-24

Putative MetA-pathway of phenol degradation;


Pssm-ID: 463920  Cd Length: 237  Bit Score: 97.94  E-value: 3.40e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511   68 NGKAELKTNAVAYRQVFFSDICGTLCTPQFIIPFVDIDARLPGSAGHTG---ETGFGDPQVGGTLFFINDPERRRYSGLL 144
Cdd:pfam13557  15 GGDLQVEAGLPRFVYVTDTTLGGASLGRYGLLPFGWLDLKLDGGGPGAYsdsRSGLGDLTLGPKILGWEDKGGNPHVALY 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511  145 TLITLPLGEYHAKNPdVSPGTNRWGATFVYNYTQGIGRDWVLEANLEAQFYAKNDDYfgsDLEQKPLYRLQAFASYDFsq 224
Cdd:pfam13557  95 LGVNLPTGDYDKNAL-ANPGLNYWSFSPTLALTYQLGPGWELSANLGYDFNGENDDT---DYQSGQEFHLDFALGYAV-- 168
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 505462511  225 sTYGALKLvhADGGELKLQGHTLDDTHQRYTQLGFELGHWLDRRNSLMF--GLSRNVATDNAFHGSQALLRL 294
Cdd:pfam13557 169 -TNGKWSV--GLVGYYYKSGGGADGDRGRVFALGPGLAYLFTPNLQLDAsaGKGLEFAARNRFEGAGLSLRF 237
SphA COG4313
Sphingosine uptake channel SphA-related outer membrane channel [Cell wall/membrane/envelope ...
96-298 1.96e-10

Sphingosine uptake channel SphA-related outer membrane channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443454  Cd Length: 303  Bit Score: 60.33  E-value: 1.96e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511  96 QFIIPFVDIDARLPGSAGHTGETGFGDPQVGGtlFFINDPERRRYSGLLTL-ITLPLGEYHAKNPdVSPGTNRWGATFVY 174
Cdd:COG4313  104 SAIVPLVSLDVDANVGGVSDSRTGLGDIYLGP--LILGWHPSPNLHVVAGLdIYAPTGSYDPNRL-ANPGLNYWTFDPTL 180
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505462511 175 NYTQGIGRDWVLEANLEAQFYAKNDDyfgSDLEQKPLYRLQAFASYDFSQS-----TYGALKLVHADggelKLQGHTLDD 249
Cdd:COG4313  181 AFTYLFDDGWELSAKLGYDFNTKNPD---TDYQSGQEFHLDYALGKHFGKGwrlglVGYYYKQLTDD----SGPGARLDG 253
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 505462511 250 THQRYTQLGFELGHWLDRRN-SLMFGLSRNVATDNAFHGSQALLRLVHVF 298
Cdd:COG4313  254 FRGRVFALGPGVGYDFPPGGfSLSLKWYHEFGARNRPEGDALWLRLSIPF 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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