|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
1-470 |
0e+00 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 1039.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:PRK09206 81 NDVSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSRLDYNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALT 400
Cdd:PRK09206 321 PLEAVSIMATICERTDRVMNSRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 401 TNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGALVPSGTTNTASVHVL 470
Cdd:PRK09206 401 TNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGALVPSGTTNTASVHVL 470
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-470 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 725.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 nDVSLKAGQTFTFTTDKsVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:COG0469 82 -PVELKKGDTFTLTTDD-VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGeNIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:COG0469 160 PGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGG-RAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSR--LDYNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILA 398
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRriLDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILA 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505807381 399 LTTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGALV-PSGTTNTASVHVL 470
Cdd:COG0469 399 LTPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVgVPGTTNTLKVHRV 471
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-470 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 723.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NDVSLKAGQTFTFTTD-KSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGN-KVICKVLNNGDLGENKGV 158
Cdd:cd00288 81 KDISLKAGDKFLVTTDpAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 159 NLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGgENIQIISKIENQEGLNNFDEILEASD 238
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKG-KDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 239 GIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKG 318
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 319 KYPLEAVTIMATICERTDRVMTSRLDYNNDNRKLR----ITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDA 394
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPrptsTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 395 TILALTTNETTARQLVLSKGVVPQLVKEIA-----STDDFYHLGKELALQSGLARKGDVVVMVSGALVPSGTTNTASVHV 469
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFEEPKpgwqeDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSGSTNTMRILT 479
|
.
gi 505807381 470 L 470
Cdd:cd00288 480 V 480
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-467 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 678.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 2 KKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGGn 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 82 DVSLKAGQTFTFTTD-KSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:TIGR01064 80 EVKLKKGDKVIITTDdIKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:TIGR01064 160 PGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:TIGR01064 240 MVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSRLDYNN----DNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATI 396
Cdd:TIGR01064 320 PVEAVQMMAKIAKEAEKALAYLTNFNDrknsDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPI 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505807381 397 LALTTNETTARQLVLSKGVVPQLVKEIAS-TDDFYHLGKELALQSGLARKGDVVVMVSG-ALVPSGTTNTASV 467
Cdd:TIGR01064 400 IAVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGgPIGGEGGTNTIRV 472
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-342 |
5.81e-179 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 504.59 E-value: 5.81e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 -NDVSLKAGQTFTFTTDKSVVG--NNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNK-VICKVLNNGDLGENK 156
Cdd:pfam00224 81 kKDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 157 GVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGgENIQIISKIENQEGLNNFDEILEA 236
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAG-KNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 237 SDGIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESA 316
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*.
gi 505807381 317 KGKYPLEAVTIMATICERTDRVMTSR 342
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHR 345
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
1-470 |
0e+00 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 1039.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:PRK09206 81 NDVSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSRLDYNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALT 400
Cdd:PRK09206 321 PLEAVSIMATICERTDRVMNSRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 401 TNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGALVPSGTTNTASVHVL 470
Cdd:PRK09206 401 TNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGALVPSGTTNTASVHVL 470
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-470 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 725.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 nDVSLKAGQTFTFTTDKsVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:COG0469 82 -PVELKKGDTFTLTTDD-VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGeNIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:COG0469 160 PGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGG-RAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSR--LDYNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILA 398
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRriLDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILA 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505807381 399 LTTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGALV-PSGTTNTASVHVL 470
Cdd:COG0469 399 LTPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVgVPGTTNTLKVHRV 471
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-470 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 723.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NDVSLKAGQTFTFTTD-KSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGN-KVICKVLNNGDLGENKGV 158
Cdd:cd00288 81 KDISLKAGDKFLVTTDpAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 159 NLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGgENIQIISKIENQEGLNNFDEILEASD 238
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKG-KDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 239 GIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKG 318
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 319 KYPLEAVTIMATICERTDRVMTSRLDYNNDNRKLR----ITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDA 394
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPrptsTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 395 TILALTTNETTARQLVLSKGVVPQLVKEIA-----STDDFYHLGKELALQSGLARKGDVVVMVSGALVPSGTTNTASVHV 469
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFEEPKpgwqeDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGSGSTNTMRILT 479
|
.
gi 505807381 470 L 470
Cdd:cd00288 480 V 480
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-467 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 678.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 2 KKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGGn 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 82 DVSLKAGQTFTFTTD-KSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:TIGR01064 80 EVKLKKGDKVIITTDdIKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:TIGR01064 160 PGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:TIGR01064 240 MVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSRLDYNN----DNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATI 396
Cdd:TIGR01064 320 PVEAVQMMAKIAKEAEKALAYLTNFNDrknsDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPI 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505807381 397 LALTTNETTARQLVLSKGVVPQLVKEIAS-TDDFYHLGKELALQSGLARKGDVVVMVSG-ALVPSGTTNTASV 467
Cdd:TIGR01064 400 IAVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGgPIGGEGGTNTIRV 472
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-462 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 624.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 nDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:PRK05826 83 -KITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:PRK05826 162 PGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPHAKIIAKIERAEAVDNIDEIIEASDGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:PRK05826 242 MVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSRLDYNNDNRKL-RITEAVCRGAVETAEKL-EAPLIVVATQGGKSARAVRKYFPDATILA 398
Cdd:PRK05826 322 PVEAVEAMARICKGAEKEFSINLSKHRLDRQFdRIDEAIAMSAMYAANHLkGVKAIVALTESGRTARLISRFRPGAPIFA 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505807381 399 LTTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGalVPSGTT 462
Cdd:PRK05826 402 VTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSG--DPMGTA 463
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-469 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 593.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:PRK06354 7 MRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NdVSLKAGQTFTFTTdKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEG--NKVICKVLNNGDLGENKGV 158
Cdd:PRK06354 87 P-IELKTGDEFILTS-REVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKadGELHCKVLVGGVLSNKKGV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 159 NLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASD 238
Cdd:PRK06354 165 NFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNGKHIPIIAKIEKQEAIDNIDAILELCD 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 239 GIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKG 318
Cdd:PRK06354 245 GLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAG 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 319 KYPLEAVTIMATICERTDRVMTSR-LDYNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATIL 397
Cdd:PRK06354 325 DYPVEAVQTMATIAVRIEKDLPYRdILSKRPEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPIL 404
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505807381 398 ALTTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGALV-PSGTTNTASVHV 469
Cdd:PRK06354 405 AVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLVgESGSTDLMKVHV 477
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-342 |
5.81e-179 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 504.59 E-value: 5.81e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 -NDVSLKAGQTFTFTTDKSVVG--NNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNK-VICKVLNNGDLGENK 156
Cdd:pfam00224 81 kKDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 157 GVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGgENIQIISKIENQEGLNNFDEILEA 236
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAG-KNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 237 SDGIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESA 316
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*.
gi 505807381 317 KGKYPLEAVTIMATICERTDRVMTSR 342
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHR 345
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
2-450 |
8.21e-178 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 507.98 E-value: 8.21e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 2 KKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGGN 81
Cdd:PLN02461 21 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 82 DVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEV--TAIEGNKVICKVLNNGDLGENKGVN 159
Cdd:PLN02461 101 PVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVlsCDVEAGTVRCRCENSAMLGERKNVN 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 160 LPGVSIALPALAEKDKQDLI-FGCEQGVDFVAASFIRKRSDVVEIREHLKAHGgENIQIISKIENQEGLNNFDEILEASD 238
Cdd:PLN02461 181 LPGVVVDLPTLTEKDKEDILqWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHA-KSILLISKVENQEGLDNFDDILAESD 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 239 GIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKG 318
Cdd:PLN02461 260 AFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAG 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 319 KYPLEAVTIMATICERTDrvmtSRLDYNNDNRK--------LRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKY 390
Cdd:PLN02461 340 AYPELAVKTMARICREAE----ASLDYGALFKEimrsaplpMSPLESLASSAVRTANKVKASLIVVLTRGGTTARLVAKY 415
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 505807381 391 FPDATILA-----LTTN--------ETTARQLVLSKGVVPQLVKEIA------STDDFYHLGKELALQSGLARKGDVVV 450
Cdd:PLN02461 416 RPAVPILSvvvpeITTDsfdwscsdEAPARHSLIYRGLIPVLAEGSAkatdseSTEEILEAAIEHAKKKGLCKPGDSVV 494
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-467 |
2.96e-161 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 465.78 E-value: 2.96e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 2 KKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKT-GKKAAILLDTKGPEIRTIKLEGG 80
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARpNANLGILLDTKGPEIRTGFLKNH 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:PTZ00066 118 KPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMNL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLI-FGCEQGVDFVAASFIRKRSDVVEIREHLKAHGgENIQIISKIENQEGLNNFDEILEASDG 239
Cdd:PTZ00066 198 PGVKVELPVIGEKDKNDILnFAIPMGCDFIALSFVQSADDVRLCRQLLGERG-RHIKIIPKIENIEGLINFDEILAESDG 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 240 IMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGK 319
Cdd:PTZ00066 277 IMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGK 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 320 YPLEAVTIMATICERTDRVMTSRLDY----NNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDAT 395
Cdd:PTZ00066 357 FPVEAVNIMAKICFEAETCIDYRVLYhaihLAVPTPVSVQEAVARSAVETAEDINAKLIIALTETGNTARLISKYRPSCT 436
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505807381 396 ILALTTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGALVP-SGTTNTASV 467
Cdd:PTZ00066 437 ILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEvAGSSNLMKV 509
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
2-470 |
4.42e-156 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 451.30 E-value: 4.42e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 2 KKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGGN 81
Cdd:PRK06247 5 RRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 82 dVSLKAGQTFTFTTDKsVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLP 161
Cdd:PRK06247 85 -VQLANGQTFRLDVDD-APGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 162 GVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLkahgGENIQIISKIENQEGLNNFDEILEASDGIM 241
Cdd:PRK06247 163 GTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKII----GGRVPVMAKIEKPQAIDRLEAIVEASDAIM 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 242 VARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYP 321
Cdd:PRK06247 239 VARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 322 LEAVTIMATICERTDRVMTSR--LDYNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILAL 399
Cdd:PRK06247 319 VEAVRTMARIIRQVERDPTYPplIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILAL 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505807381 400 TTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMVSGalVP---SGTTNTASVHVL 470
Cdd:PRK06247 399 TPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAG--VPpgtPGSTNMLRIAYI 470
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
28-452 |
4.68e-124 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 368.99 E-value: 4.68e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 28 MNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGGNDVsLKAGQTFTFTTDKSV--VGNNEI 105
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAV-MERGATCYVTTDPAFadKGTKDK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 106 VAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVI-CKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQ 184
Cdd:PTZ00300 80 FYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQTLkCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 185 GVDFVAASFIRKRSDVVEIREHLKAHGGEnIQIISKIENQEGLNNFDEILEASDGIMVARGDMGVEIPVEEVIFAQKMII 264
Cdd:PTZ00300 160 GVDMIFASFIRSAEQVGEVRKALGAKGGD-IMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 265 EKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVTIMATICERTDRVMTSRLD 344
Cdd:PTZ00300 239 SKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYVF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 345 YNNDNR----KLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALTTNETTARQLVLSKGVV---- 416
Cdd:PTZ00300 319 FNSIKKlqpiPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVEsvff 398
|
410 420 430
....*....|....*....|....*....|....*..
gi 505807381 417 -PQLVKEIASTDDFYHLGKELALQSGLARKGDVVVMV 452
Cdd:PTZ00300 399 dAERLGHDEGKEQRVAMGVGFAKSKGYVQSGDLMVVV 435
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
2-462 |
1.50e-116 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 353.85 E-value: 1.50e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 2 KKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKA-AILLDTKGPEIRTIKLEgg 80
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQSKDNViAIMLDTKGPEVRSGDLP-- 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NDVSLKAGQTFTFTTdKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL 160
Cdd:PLN02623 188 QPIMLEEGQEFTFTI-KRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNV 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGEnIQIISKIENQEGLNNFDEILEASDGI 240
Cdd:PLN02623 267 RGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNAD-IHVIVKIESADSIPNLHSIITASDGA 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
Cdd:PLN02623 346 MVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKF 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 321 PLEAVTIMATICERTDRVMTSRLDYNNDNR--KLRITEAVCRGAVETAEKLEAPlIVVATQGGKSARAVRKYFPDATILA 398
Cdd:PLN02623 426 PLKAVKVMHTVALRTEATLPEGTTPPNLGQafKNHMSEMFAFHATMMANTLGTS-IIVFTRTGFMAILLSHYRPSGTIFA 504
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505807381 399 LTTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKELALQSGLARKGDVVvmvsgALVPSGTT 462
Cdd:PLN02623 505 FTNEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEEV-----ALVQSGRQ 563
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
4-450 |
3.99e-114 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 345.89 E-value: 3.99e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 4 TKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKlEGGNDV 83
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVIN-KTEKPI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 84 SLKAGQTFTFTTDKSVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGL--------IGMEVTAIEGNKVICKVLNNGDL-GE 154
Cdd:PLN02765 109 SLKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVGQYLftgsettsVWLEVDEVKGDDVVCTVKNSATLaGS 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 155 NKGVNLPGVSIALPALAEKDKQDL-IFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEI 233
Cdd:PLN02765 189 LFTLHVSQVRIDLPTLSEKDKEVIsTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGLSQTQIFAKIENVEGLTHFDEI 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 234 LEASDGIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITaTQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSG 313
Cdd:PLN02765 269 LQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILLGA 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 314 ESAKGKYPLEAVTIMATICERTDRVmtsrldYNNDNRKLRIT----------EAVCRGAVETAEKLEAPLIVVATQGGKS 383
Cdd:PLN02765 348 ETLRGLYPVETISTVGRICAEAEKV------FNQDLYFKKTVkyvgepmshlESIASSAVRAAIKVKASVIIVFTSSGRA 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 384 ARAVRKYFPDATILA-----LTTN--------ETTARQLVLSKGVVPQLVKEIASTDDFYHLGK---ELAL----QSGLA 443
Cdd:PLN02765 422 ARLIAKYRPTMPVLSvviprLKTNqlkwsftgAFQARQCLIVRGLFPMLADPRHSAESTSATNEsvlKVALdhgkAAGVI 501
|
....*..
gi 505807381 444 RKGDVVV 450
Cdd:PLN02765 502 KSHDRVV 508
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
1-470 |
1.44e-102 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 315.53 E-value: 1.44e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 1 MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG 80
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDLGGA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 81 NDVSLKAGQTFTFTTDKSVVGNNE-IVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLgenkgvn 159
Cdd:PLN02762 104 SSAKAEDGEEWTFTVRKFDGSRPEfTIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPGLL------- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 160 LPGVSIA--------------LPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHG-GENIQIISKIENQ 224
Cdd:PLN02762 177 LPRANLTfwrdgslvrernamLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSrDSDIGVIAKIESL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 225 EGLNNFDEILEASDGIMVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILD 304
Cdd:PLN02762 257 DSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQ 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 305 GTDAVMLSGESAKGKYPLEAVTIMATICERTDRvmTSRLDYNNDNRKL---------RITEAVCRGAVETAEKLEAPLIV 375
Cdd:PLN02762 337 RADALMLSGESAMGLYPEKALSVLRSVSLRMEL--WSREEKRHEALELpqlssslsdRISEEICNSAAKMANNLGVDAIF 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 376 VATQGGKSARAVRKYFPDATILALTTNETTARQLVLSKGVVPQLVKEiaSTDDFYHLGKELAL--QSGLARKGDVVVMVS 453
Cdd:PLN02762 415 VYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDF--SDDMESNLNKTFSLlkARGMIKSGDLVIAVS 492
|
490
....*....|....*..
gi 505807381 454 GaLVPSGTTNTASVHVL 470
Cdd:PLN02762 493 D-LTPSSMLQSIQVRNV 508
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
7-338 |
3.81e-98 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 299.17 E-value: 3.81e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 7 VCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTgkkaAILLDTKGPEIRTIKLEGgNDVSLK 86
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSI----KILGDVQGPKIRLGEIKG-EQITLQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 87 AGQTFTFTTDKsVVGNNEIVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIA 166
Cdd:PRK06739 81 AGDSFILHTQP-VTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 167 LPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGIMVARGD 246
Cdd:PRK06739 160 LPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPNLIAKIETMEAIENFQDICKEADGIMIARGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 247 MGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVT 326
Cdd:PRK06739 240 LGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVS 319
|
330
....*....|..
gi 505807381 327 IMATICERTDRV 338
Cdd:PRK06739 320 TLRLVSEFAEHV 331
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
266-469 |
8.64e-55 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 185.49 E-value: 8.64e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 266 KCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVTIMATICERTDRVMTSR--L 343
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYReqR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 344 DYNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALTTNETTARQLVLSKGVVPQLVKEI 423
Cdd:COG3848 81 VPRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEES 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 505807381 424 ASTDDFYHLGKELALQSGLARKGDVVVMVSGALVP-SGTTNTASVHV 469
Cdd:COG3848 161 ASTDEMFAVAVALALEAGLVKDGDLVVITAGVPVGvSGTTNLLKVHV 207
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
17-337 |
2.61e-51 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 180.98 E-value: 2.61e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 17 EEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMNKTGKKAAILLDTKGPEIRTIKLEGG-NDVSLKAGQTFTFTT 95
Cdd:PRK08187 149 PDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVAGPlGKTRLYTGDRLALVA 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 96 DKSVVGNNEI---VAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGE----NKGVNLPGVSIALP 168
Cdd:PRK08187 229 QGPPRRIDEEhfqVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTHARPKGLklkpEKGLNFPDTALDLP 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 169 ALAEKDKQDLIFGCEQGvDFVAASFIRKRSDVVEIREHLKAHGGENIQ---IISKIENQEGLNNFDEILEASDG-----I 240
Cdd:PRK08187 309 ALTEKDRADLDFVARHA-DLVGYSFVQSPGDVEALQAALAARRPDDWRklgLVLKIETPRAVANLPELIVQAAGrqpfgV 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 241 MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAilDGTDAVMLSgesaKGKY 320
Cdd:PRK08187 388 MIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA--ARAECVMLN----KGPY 461
|
330
....*....|....*..
gi 505807381 321 PLEAVTIMATICERTDR 337
Cdd:PRK08187 462 LVEAVTFLDDLLARMDG 478
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
116-337 |
2.43e-41 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 155.88 E-value: 2.43e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 116 DLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGEN----KGVNLPGVSIALPALAEKDKQDLIFGCEQGvDFVAA 191
Cdd:PRK14725 372 AARVGERVWFDDGKIGAVVVKVEADEVELRITHARPGGSKlkagKGINLPDSHLPLPALTDKDLEDLAFVAKHA-DIVAL 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 192 SFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEI-LEA----SDGIMVARGDMGVEIPVEEVIFAQKMIIEK 266
Cdd:PRK14725 451 SFVRSPEDVRLLLDALEKLGADDLGVVLKIETRRAFENLPRIlLEAmrhpRFGVMIARGDLAVEVGFERLAEVQEEILWL 530
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 505807381 267 CIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILdgTDAVMLSgesaKGKYPLEAVTIMATICERTDR 337
Cdd:PRK14725 531 CEAAHVPVIWATQVLESLAKKGLPSRAEITDAAMALR--AECVMLN----KGPHIVEAVRVLDDILRRMEE 595
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
356-468 |
1.95e-34 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 124.90 E-value: 1.95e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505807381 356 EAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALTTNETTARQLVLSKGVVPQLVKEIASTDDFYHLGKE 435
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVK 80
|
90 100 110
....*....|....*....|....*....|....
gi 505807381 436 LALQSGLARKGDVVVMVSG-ALVPSGTTNTASVH 468
Cdd:pfam02887 81 VAKEAGLVKKGDLVVITAGvPFGVSGTTNTLKVI 114
|
|
| |
