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Conserved domains on  [gi|505944493|ref|WP_015727729|]
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MULTISPECIES: LysR family transcriptional regulator [Vibrio]

Protein Classification

LysR family transcriptional regulator( domain architecture ID 11426483)

LysR family transcriptional regulator containing an N-terminal HTH (helix-turn-helix) DNA-binding domain and a C-terminal substrate binding domain, which is structurally homologous to the type 2 periplasmic-binding (PBP2) fold proteins

CATH:  3.40.190.10
Gene Ontology:  GO:0003700|GO:0003677|GO:0006355
PubMed:  19047729|8257110|15808743
SCOP:  4000316

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LysR COG0583
DNA-binding transcriptional regulator, LysR family [Transcription];
8-167 1.16e-26

DNA-binding transcriptional regulator, LysR family [Transcription];


:

Pssm-ID: 440348 [Multi-domain]  Cd Length: 256  Bit Score: 104.56  E-value: 1.16e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMSMYEKLFK 86
Cdd:COG0583    1 MDLRQLRAFVAVAEEGSFTAAAERLGVSQPAVSRQIRRLEEELGVPLFERtGRGLRLTEAGERLLERARRILAELEEAEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  87 DLEKVDTREQ--YNIAIADSFCPILVEKVVSEFRALN-NTDLAITSFSTTSTID-IAN--FDVIFSLNRLSSENGNSYQL 160
Cdd:COG0583   81 ELRALRGGPRgtLRIGAPPSLARYLLPPLLARFRARHpGVRLELREGNSDRLVDaLLEgeLDLAIRLGPPPDPGLVARPL 160


                 ....*..
gi 505944493 161 RSSSYVI 167
Cdd:COG0583  161 GEERLVL 167
 
Name Accession Description Interval E-value
LysR COG0583
DNA-binding transcriptional regulator, LysR family [Transcription];
8-167 1.16e-26

DNA-binding transcriptional regulator, LysR family [Transcription];


Pssm-ID: 440348 [Multi-domain]  Cd Length: 256  Bit Score: 104.56  E-value: 1.16e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMSMYEKLFK 86
Cdd:COG0583    1 MDLRQLRAFVAVAEEGSFTAAAERLGVSQPAVSRQIRRLEEELGVPLFERtGRGLRLTEAGERLLERARRILAELEEAEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  87 DLEKVDTREQ--YNIAIADSFCPILVEKVVSEFRALN-NTDLAITSFSTTSTID-IAN--FDVIFSLNRLSSENGNSYQL 160
Cdd:COG0583   81 ELRALRGGPRgtLRIGAPPSLARYLLPPLLARFRARHpGVRLELREGNSDRLVDaLLEgeLDLAIRLGPPPDPGLVARPL 160


                 ....*..
gi 505944493 161 RSSSYVI 167
Cdd:COG0583  161 GEERLVL 167
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
13-68 5.09e-18

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 75.88  E-value: 5.09e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 505944493   13 LRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRKE-GFGLTKHGK 68
Cdd:pfam00126   4 LRLFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFERTTrGVRLTEAGE 60
LysR_Sec_metab NF040786
selenium metabolism-associated LysR family transcriptional regulator; LysR family ...
 8-118 2.55e-16

selenium metabolism-associated LysR family transcriptional regulator; LysR family transcriptional regulators regularly appear encoded adjacent to selenecysteine incorporation proteins such as SelB. This model represents one especially well-conserved subgroup of such transcription factors from species such as Merdimonas faecis, Sellimonas intestinalis, Syntrophotalea acetylenica, and Hydrogenivirga caldilitoris. Seed alignment members were selected by proximity to selB, but not all family members are expected to have similar genomic locations.


Pssm-ID: 468737 [Multi-domain]  Cd Length: 298  Bit Score: 77.27  E-value: 2.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYADQTMSMYEKLFK 86
Cdd:NF040786   1 MNLKQLEAFVNVAEYKSFSKAAKKLFLTQPTISAHISSLEKELGVRLFVRNtKEVSLTEDGKLLYEYAKEMLDLWEKLEE 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 505944493  87 DLEKvdTREQY--NIAIADSFCP--ILVEKVVSEFR 118
Cdd:NF040786  81 EFDR--YGKESkgVLRIGASTIPgqYLLPELLKKFK 114
rbcR CHL00180
LysR transcriptional regulator; Provisional
 13-104 4.62e-14

LysR transcriptional regulator; Provisional


Pssm-ID: 177082 [Multi-domain]  Cd Length: 305  Bit Score: 70.82  E-value: 4.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  13 LRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMSMYEKLFKDLEKV 91
Cdd:CHL00180  10 LRILKAIATEGSFKKAAESLYISQPAVSLQIKNLEKQLNIPLFDRsKNKASLTEAGELLLRYGNRILALCEETCRALEDL 89

                         90
                 ....*....|...
gi 505944493  92 DTREQYNIAIADS 104
Cdd:CHL00180  90 KNLQRGTLIIGAS 102
 
Name Accession Description Interval E-value
LysR COG0583
DNA-binding transcriptional regulator, LysR family [Transcription];
8-167 1.16e-26

DNA-binding transcriptional regulator, LysR family [Transcription];


Pssm-ID: 440348 [Multi-domain]  Cd Length: 256  Bit Score: 104.56  E-value: 1.16e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMSMYEKLFK 86
Cdd:COG0583    1 MDLRQLRAFVAVAEEGSFTAAAERLGVSQPAVSRQIRRLEEELGVPLFERtGRGLRLTEAGERLLERARRILAELEEAEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  87 DLEKVDTREQ--YNIAIADSFCPILVEKVVSEFRALN-NTDLAITSFSTTSTID-IAN--FDVIFSLNRLSSENGNSYQL 160
Cdd:COG0583   81 ELRALRGGPRgtLRIGAPPSLARYLLPPLLARFRARHpGVRLELREGNSDRLVDaLLEgeLDLAIRLGPPPDPGLVARPL 160


                 ....*..
gi 505944493 161 RSSSYVI 167
Cdd:COG0583  161 GEERLVL 167
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
13-68 5.09e-18

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 75.88  E-value: 5.09e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 505944493   13 LRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRKE-GFGLTKHGK 68
Cdd:pfam00126   4 LRLFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFERTTrGVRLTEAGE 60
LysR_Sec_metab NF040786
selenium metabolism-associated LysR family transcriptional regulator; LysR family ...
 8-118 2.55e-16

selenium metabolism-associated LysR family transcriptional regulator; LysR family transcriptional regulators regularly appear encoded adjacent to selenecysteine incorporation proteins such as SelB. This model represents one especially well-conserved subgroup of such transcription factors from species such as Merdimonas faecis, Sellimonas intestinalis, Syntrophotalea acetylenica, and Hydrogenivirga caldilitoris. Seed alignment members were selected by proximity to selB, but not all family members are expected to have similar genomic locations.


Pssm-ID: 468737 [Multi-domain]  Cd Length: 298  Bit Score: 77.27  E-value: 2.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYADQTMSMYEKLFK 86
Cdd:NF040786   1 MNLKQLEAFVNVAEYKSFSKAAKKLFLTQPTISAHISSLEKELGVRLFVRNtKEVSLTEDGKLLYEYAKEMLDLWEKLEE 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 505944493  87 DLEKvdTREQY--NIAIADSFCP--ILVEKVVSEFR 118
Cdd:NF040786  81 EFDR--YGKESkgVLRIGASTIPgqYLLPELLKKFK 114
rbcR CHL00180
LysR transcriptional regulator; Provisional
 13-104 4.62e-14

LysR transcriptional regulator; Provisional


Pssm-ID: 177082 [Multi-domain]  Cd Length: 305  Bit Score: 70.82  E-value: 4.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  13 LRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMSMYEKLFKDLEKV 91
Cdd:CHL00180  10 LRILKAIATEGSFKKAAESLYISQPAVSLQIKNLEKQLNIPLFDRsKNKASLTEAGELLLRYGNRILALCEETCRALEDL 89

                         90
                 ....*....|...
gi 505944493  92 DTREQYNIAIADS 104
Cdd:CHL00180  90 KNLQRGTLIIGAS 102
PRK09986 PRK09986
LysR family transcriptional regulator;
1-101 1.24e-12

LysR family transcriptional regulator;


Pssm-ID: 182183 [Multi-domain]  Cd Length: 294  Bit Score: 66.67  E-value: 1.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   1 MKTVHRmIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMS 79
Cdd:PRK09986   1 MERLYR-IDLKLLRYFLAVAEELHFGRAAARLNISQPPLSIHIKELEDQLGTPLFIRhSRSVVLTHAGKILMEESRRLLD 79

                         90       100
                 ....*....|....*....|..
gi 505944493  80 MYEKLFKDLEKVDTREQYNIAI 101
Cdd:PRK09986  80 NAEQSLARVEQIGRGEAGRIEI 101
PRK13348 PRK13348
HTH-type transcriptional regulator ArgP;
7-104 2.13e-12

HTH-type transcriptional regulator ArgP;


Pssm-ID: 237357 [Multi-domain]  Cd Length: 294  Bit Score: 65.76  E-value: 2.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   7 MIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRKEGFGLTKHGKVLLEYADQtMSMYE-KLF 85
Cdd:PRK13348   1 MLDYKQLEALAAVVETGSFERAARRLHVTPSAVSQRIKALEESLGQPLLVRGRPCRPTPAGQRLLRHLRQ-VALLEaDLL 79

                         90       100
                 ....*....|....*....|.
gi 505944493  86 KDL-EKVDTREQYNIAI-ADS 104
Cdd:PRK13348  80 STLpAERGSPPTLAIAVnADS 100
PRK10094 PRK10094
HTH-type transcriptional activator AllS;
7-101 3.26e-12

HTH-type transcriptional activator AllS;


Pssm-ID: 182237 [Multi-domain]  Cd Length: 308  Bit Score: 65.60  E-value: 3.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   7 MIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMSMYEKLF 85
Cdd:PRK10094   1 MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRtTRSVTLTAAGEHLLSQARDWLSWLESMP 80

                         90
                 ....*....|....*...
gi 505944493  86 KDLEKVD--TREQYNIAI 101
Cdd:PRK10094  81 SELQQVNdgVERQVNIVI 98
PRK15092 PRK15092
DNA-binding transcriptional repressor LrhA; Provisional
 1-134 5.15e-12

DNA-binding transcriptional repressor LrhA; Provisional


Pssm-ID: 237907 [Multi-domain]  Cd Length: 310  Bit Score: 65.05  E-value: 5.15e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   1 MKTVHRMI---DVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRkEGFG--LTKHGKVLLEYA- 74
Cdd:PRK15092   1 MINANRPIinlDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR-HGRNklLTEHGIQLLGYAr 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  75 -------DQTMS-MYEklfkDLEKV-------DTreqyniaiADSFCPILVEKVVSEF----------------RALNN- 122
Cdd:PRK15092  80 kilrfndEACSSlMYS----NLQGVltigasdDT--------ADTILPFLLNRVSSVYpklaldvrvkrnafmmEMLESq 147

                        170
                 ....*....|...
gi 505944493 123 -TDLAITSFSTTS 134
Cdd:PRK15092 148 eVDLAVTTHRPSS 160
PRK09906 PRK09906
DNA-binding transcriptional regulator HcaR; Provisional
 8-127 6.20e-12

DNA-binding transcriptional regulator HcaR; Provisional


Pssm-ID: 182137 [Multi-domain]  Cd Length: 296  Bit Score: 64.41  E-value: 6.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMSMYEKLFK 86
Cdd:PRK09906   1 MELRHLRYFVAVAEELNFTKAAEKLHTAQPSLSQQIKDLENCVGVPLLVRdKRKVALTAAGEVFLQDARAILEQAEKAKL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 505944493  87 DLEKVdTREQYNIAIAdsFCPI----LVEKVVSEFRaLNNTDLAI 127
Cdd:PRK09906  81 RARKI-VQEDRQLTIG--FVPSaevnLLPKVLPMFR-LRHPDTLI 121
PRK03635 PRK03635
ArgP/LysG family DNA-binding transcriptional regulator;
7-104 1.27e-11

ArgP/LysG family DNA-binding transcriptional regulator;


Pssm-ID: 235144 [Multi-domain]  Cd Length: 294  Bit Score: 63.64  E-value: 1.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   7 MIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRKEGFGLTKHGKVLLEYADQTMSMYEKLFK 86
Cdd:PRK03635   1 MLDYKQLEALAAVVREGSFERAAQKLHITQSAVSQRIKALEERVGQVLLVRTQPCRPTEAGQRLLRHARQVRLLEAELLG 80

                         90       100
                 ....*....|....*....|
gi 505944493  87 DL-EKVDTREQYNIAI-ADS 104
Cdd:PRK03635  81 ELpALDGTPLTLSIAVnADS 100
PRK03601 PRK03601
HTH-type transcriptional regulator HdfR;
8-79 1.31e-11

HTH-type transcriptional regulator HdfR;


Pssm-ID: 235137 [Multi-domain]  Cd Length: 275  Bit Score: 63.50  E-value: 1.31e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYADQTMS 79
Cdd:PRK03601   1 MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRhRNNIRLTAAGERLLPYAETLMN 73
PRK11242 PRK11242
DNA-binding transcriptional regulator CynR; Provisional
 11-120 7.38e-11

DNA-binding transcriptional regulator CynR; Provisional


Pssm-ID: 183051 [Multi-domain]  Cd Length: 296  Bit Score: 61.51  E-value: 7.38e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  11 KYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIF------VRkegfgLTKHGKVLLEYADQTMSMYEKL 84
Cdd:PRK11242   4 RHIRYFLAVAEHGNFTRAAEALHVSQPTLSQQIRQLEESLGVQLFdrsgrtVR-----LTDAGEVYLRYARRALQDLEAG 78

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 505944493  85 FKDLEKVD--TREQYNIAIADSFCPILVEKVVSEFRAL 120
Cdd:PRK11242  79 RRAIHDVAdlSRGSLRLAMTPTFTAYLIGPLIDAFHAR 116
PRK09791 PRK09791
LysR family transcriptional regulator;
8-120 3.38e-10

LysR family transcriptional regulator;


Pssm-ID: 182077 [Multi-domain]  Cd Length: 302  Bit Score: 59.39  E-value: 3.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYADQTMsmyEKLFK 86
Cdd:PRK09791   5 VKIHQIRAFVEVARQGSIRGASRMLNMSQPALTKSIQELEEGLAAQLFFRRsKGVTLTDAGESFYQHASLIL---EELRA 81

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 505944493  87 DLEKVDTRE-----QYNIAIADSFCPILVEKVVSEFRAL 120
Cdd:PRK09791  82 AQEDIRQRQgqlagQINIGMGASIARSLMPAVISRFHQQ 120
PRK11139 PRK11139
DNA-binding transcriptional activator GcvA; Provisional
 13-58 1.32e-09

DNA-binding transcriptional activator GcvA; Provisional


Pssm-ID: 182990 [Multi-domain]  Cd Length: 297  Bit Score: 57.55  E-value: 1.32e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 505944493  13 LRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK 58
Cdd:PRK11139  11 LRAFEAAARHLSFTRAAEELFVTQAAVSHQIKALEDFLGLKLFRRR 56
PRK12682 PRK12682
transcriptional regulator CysB-like protein; Reviewed
 8-78 1.77e-09

transcriptional regulator CysB-like protein; Reviewed


Pssm-ID: 183679 [Multi-domain]  Cd Length: 309  Bit Score: 57.31  E-value: 1.77e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505944493   8 IDVKYLRTFSQVAKHK-SFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR--KEGFGLTKHGKVLLEYADQTM 78
Cdd:PRK12682   1 MNLQQLRFVREAVRRNlNLTEAAKALHTSQPGVSKAIIELEEELGIEIFIRhgKRLKGLTEPGKAVLDVIERIL 74
PRK15421 PRK15421
HTH-type transcriptional regulator MetR;
7-119 2.74e-09

HTH-type transcriptional regulator MetR;


Pssm-ID: 185319 [Multi-domain]  Cd Length: 317  Bit Score: 56.95  E-value: 2.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   7 MIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYADQTMSMYEKLF 85
Cdd:PRK15421   1 MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRLGFRLFVRKsQPLRFTPQGEILLQLANQVLPQISQAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 505944493  86 KDL-EKVDTReqYNIAIADSFCPILVEKVVSEFRA 119
Cdd:PRK15421  81 QACnEPQQTR--LRIAIECHSCIQWLTPALENFHK 113
PRK10341 PRK10341
transcriptional regulator TdcA;
11-136 1.91e-08

transcriptional regulator TdcA;


Pssm-ID: 182391 [Multi-domain]  Cd Length: 312  Bit Score: 54.48  E-value: 1.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  11 KYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYADQTmsmyeklfkdle 89
Cdd:PRK10341  10 QHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELIVRKnTGVTLTPAGQVLLSRSESI------------ 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 505944493  90 kvdTREqyniaiadsfcpilVEKVVSEFRALNNTDLAITSFSTTSTI 136
Cdd:PRK10341  78 ---TRE--------------MKNMVNEINGMSSEAVVDVSFGFPSLI 107
PRK12683 PRK12683
transcriptional regulator CysB-like protein; Reviewed
 26-75 1.97e-08

transcriptional regulator CysB-like protein; Reviewed


Pssm-ID: 237172 [Multi-domain]  Cd Length: 309  Bit Score: 54.28  E-value: 1.97e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 505944493  26 TAAAESLFMTQPAVSQHIKKIENTIGASIFVR--KEGFGLTKHGKVLLEYAD 75
Cdd:PRK12683  20 TEVANALYTSQSGVSKQIKDLEDELGVEIFIRrgKRLTGLTEPGKELLQIVE 71
PRK12684 PRK12684
CysB family HTH-type transcriptional regulator;
13-102 2.19e-08

CysB family HTH-type transcriptional regulator;


Pssm-ID: 237173 [Multi-domain]  Cd Length: 313  Bit Score: 54.21  E-value: 2.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  13 LRTFSQVAKHK-SFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR--KEGFGLTKHGKVLLEYADQTMSMYEKLFKDLE 89
Cdd:PRK12684   6 LRFVREAVRQNfNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRhgKRLRGLTEPGRIILASVERILQEVENLKRVGK 85

                         90
                 ....*....|...
gi 505944493  90 KVDTREQYNIAIA 102
Cdd:PRK12684  86 EFAAQDQGNLTIA 98
PRK09801 PRK09801
LysR family transcriptional regulator;
11-105 3.65e-08

LysR family transcriptional regulator;


Pssm-ID: 182085 [Multi-domain]  Cd Length: 310  Bit Score: 53.50  E-value: 3.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  11 KYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYADQTMSMYEKLFKDLE 89
Cdd:PRK09801   9 KDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSaRGVALTESGQRCYEHALEILTQYQRLVDDVT 88

                         90
                 ....*....|....*.
gi 505944493  90 KVDTREQYNIAIADSF 105
Cdd:PRK09801  89 QIKTRPEGMIRIGCSF 104
PRK10086 PRK10086
DNA-binding transcriptional regulator DsdC;
13-68 1.87e-07

DNA-binding transcriptional regulator DsdC;


Pssm-ID: 182231 [Multi-domain]  Cd Length: 311  Bit Score: 51.54  E-value: 1.87e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 505944493  13 LRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGK 68
Cdd:PRK10086  19 LHTFEVAARHQSFALAADELSLTPSAVSHRINQLEEELGIKLFVRsHRKVELTEEGK 75
cbl PRK12679
HTH-type transcriptional regulator Cbl;
22-120 3.02e-07

HTH-type transcriptional regulator Cbl;


Pssm-ID: 183676 [Multi-domain]  Cd Length: 316  Bit Score: 50.96  E-value: 3.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  22 HKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR--KEGFGLTKHGKVLLEYADQTMSMYEKL--FKDLEKVDTREQY 97
Cdd:PRK12679  16 DYNLTEVANMLFTSQSGVSRHIRELEDELGIEIFIRrgKRLLGMTEPGKALLVIAERILNEASNVrrLADLFTNDTSGVL 95

                         90       100
                 ....*....|....*....|...
gi 505944493  98 NIAIADSFCPILVEKVVSEFRAL 120
Cdd:PRK12679  96 TIATTHTQARYSLPEVIKAFREL 118
nhaR PRK11062
transcriptional activator NhaR; Provisional
 8-113 3.84e-07

transcriptional activator NhaR; Provisional


Pssm-ID: 182938 [Multi-domain]  Cd Length: 296  Bit Score: 50.39  E-value: 3.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRKeGFGL--TKHGKVLLEYADQTMSM-YEKL 84
Cdd:PRK11062   4 INYNHLYYFWMVCKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRK-GRGLepTELGELVFRYADKMFTLsQEML 82

                         90       100       110
                 ....*....|....*....|....*....|...
gi 505944493  85 fkDLekVDTREQYNI----AIADSFCPILVEKV 113
Cdd:PRK11062  83 --DI--VNYRKESNLlfdvGVADALSKRLVSRV 111
PRK10082 PRK10082
hypochlorite stress DNA-binding transcriptional regulator HypT;
8-148 5.64e-06

hypochlorite stress DNA-binding transcriptional regulator HypT;


Pssm-ID: 182228 [Multi-domain]  Cd Length: 303  Bit Score: 46.97  E-value: 5.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVlleYADQTMSMYEKLFK 86
Cdd:PRK10082  11 IETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSRRIRALEQAIGVELFNRQvTPLQLSEQGKI---FHSQIRHLLQQLES 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  87 DLEKVDTREQY-----NIAIADSFCPILVEKVVSEFRALNNtdLAITSFSTTSTIDI---ANFDVIFSLN 148
Cdd:PRK10082  88 NLAELRGGSDYaqrkiKIAAAHSLSLGLLPSIISQMPPLFT--WAIEAIDVDEAVDKlreGQSDCIFSFH 155
cysB PRK12681
HTH-type transcriptional regulator CysB;
13-79 4.79e-05

HTH-type transcriptional regulator CysB;


Pssm-ID: 183678 [Multi-domain]  Cd Length: 324  Bit Score: 44.12  E-value: 4.79e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493  13 LRTFSQVAKHK-SFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR--KEGFGLTKHGKVLLEYADQTMS 79
Cdd:PRK12681   6 LRYIVEVVNHNlNVSATAEGLYTSQPGISKQVRMLEDELGIQIFARsgKHLTQVTPAGEEIIRIAREILS 75
PRK11151 PRK11151
DNA-binding transcriptional regulator OxyR; Provisional
 9-88 8.91e-05

DNA-binding transcriptional regulator OxyR; Provisional


Pssm-ID: 182999 [Multi-domain]  Cd Length: 305  Bit Score: 43.09  E-value: 8.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   9 DVKYLrtfSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIF---VRKEGFglTKHGKVLLEYADQTMSmyE-KL 84
Cdd:PRK11151   5 DLEYL---VALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLertSRKVLF--TQAGLLLVDQARTVLR--EvKV 77


                 ....
gi 505944493  85 FKDL 88
Cdd:PRK11151  78 LKEM 81
PRK10632 PRK10632
HTH-type transcriptional activator AaeR;
7-69 1.96e-04

HTH-type transcriptional activator AaeR;


Pssm-ID: 182601 [Multi-domain]  Cd Length: 309  Bit Score: 42.05  E-value: 1.96e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505944493   7 MIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKV 69
Cdd:PRK10632   1 MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRStRSIGLTEAGRI 64
PRK10837 PRK10837
putative DNA-binding transcriptional regulator; Provisional
 8-86 3.08e-04

putative DNA-binding transcriptional regulator; Provisional


Pssm-ID: 182768 [Multi-domain]  Cd Length: 290  Bit Score: 41.60  E-value: 3.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   8 IDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRKeGFGL--TKHGKVLLEYA----DQTMSMy 81
Cdd:PRK10837   3 ITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRV-GKRLvvNEHGRLLYPRAlallEQAVEI- 80


                 ....*
gi 505944493  82 EKLFK 86
Cdd:PRK10837  81 EQLFR 85
PRK11233 PRK11233
nitrogen assimilation transcriptional regulator; Provisional
 13-74 3.62e-04

nitrogen assimilation transcriptional regulator; Provisional


Pssm-ID: 183045 [Multi-domain]  Cd Length: 305  Bit Score: 41.21  E-value: 3.62e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 505944493  13 LRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR-KEGFGLTKHGKVLLEYA 74
Cdd:PRK11233   6 LKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELNQQLLIRtKRGVTPTEAGKILYTHA 68
PRK11482 PRK11482
DNA-binding transcriptional regulator;
6-78 1.14e-03

DNA-binding transcriptional regulator;


Pssm-ID: 183159 [Multi-domain]  Cd Length: 317  Bit Score: 39.71  E-value: 1.14e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 505944493   6 RMIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYADQTM 78
Cdd:PRK11482  27 RNIDLNLLTIFEAVYVHKGIVNAAKILNLTPSAISQSIQKLRVIFPDPLFIRKgQGVTPTAYATHLHEYISQGL 100
leuO PRK09508
leucine transcriptional activator; Reviewed
 1-57 1.51e-03

leucine transcriptional activator; Reviewed


Pssm-ID: 181918 [Multi-domain]  Cd Length: 314  Bit Score: 39.62  E-value: 1.51e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 505944493   1 MKTVHRMIDVKYLRTFSQVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVR 57
Cdd:PRK09508  15 SEPQLRMVDLNLLTVFDAVMQEQNITRAAHNLGMSQPAVSNAVARLKVMFNDELFVR 71
PRK11074 PRK11074
putative DNA-binding transcriptional regulator; Provisional
 7-96 2.24e-03

putative DNA-binding transcriptional regulator; Provisional


Pssm-ID: 182948 [Multi-domain]  Cd Length: 300  Bit Score: 38.77  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 505944493   7 MIDVkylrtfsqVAKHKSFTAAAESLFMTQPAVSQHIKKIENTIGASIFVRK-EGFGLTKHGKVLLEYAdqtmsmyEKLF 85
Cdd:PRK11074   9 VVDA--------VARTGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRhRDVELTPAGEWFVKEA-------RSVI 73

                         90
                 ....*....|.
gi 505944493  86 KDLEkvDTREQ 96
Cdd:PRK11074  74 KKMQ--ETRRQ 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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