|
Name |
Accession |
Description |
Interval |
E-value |
| gmk |
PRK00300 |
guanylate kinase; Provisional |
1-206 |
2.97e-135 |
|
guanylate kinase; Provisional
Pssm-ID: 234719 Cd Length: 205 Bit Score: 377.12 E-value: 2.97e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 1 MAQGTLYIVSAPSGAGKSSLIQAFLKTQPlyDSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGN 80
Cdd:PRK00300 2 MRRGLLIVLSGPSGAGKSTLVKALLERDP--NLQLSVSATTRAPRPGEVDGVDYFFVSKEEFEEMIENGEFLEWAEVFGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 81 YYGTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY 160
Cdd:PRK00300 80 YYGTPRSPVEEALAAGKDVLLEIDWQGARQVKKKMPDAVSIFILPPSLEELERRLRGRGTDSEEVIARRLAKAREEIAHA 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 506223188 161 AEYDYLIVNDDFDAALADLKIILRAERLRMSRQKQRHDALITKLLA 206
Cdd:PRK00300 160 SEYDYVIVNDDLDTALEELKAIIRAERLRRSRQQQRHAELIEELLA 205
|
|
| Gmk |
COG0194 |
Guanylate kinase [Nucleotide transport and metabolism]; |
3-194 |
8.55e-124 |
|
Guanylate kinase [Nucleotide transport and metabolism];
Pssm-ID: 439964 Cd Length: 190 Bit Score: 347.44 E-value: 8.55e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 3 QGTLYIVSAPSGAGKSSLIQAFLKTQPlyDSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYY 82
Cdd:COG0194 1 RGKLIVLSGPSGAGKTTLVKALLERDP--DLRFSVSATTRPPRPGEVDGVDYHFVSREEFERMIENGEFLEWAEVHGNYY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 83 GTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAE 162
Cdd:COG0194 79 GTPKAEVEEALAAGKDVLLEIDVQGARQVKKKFPDAVSIFILPPSLEELERRLRGRGTDSEEVIERRLAKAREELAHADE 158
|
170 180 190
....*....|....*....|....*....|..
gi 506223188 163 YDYLIVNDDFDAALADLKIILRAERLRMSRQK 194
Cdd:COG0194 159 FDYVVVNDDLDRAVEELKAIIRAERLRRERQA 190
|
|
| guanyl_kin |
TIGR03263 |
guanylate kinase; Members of this family are the enzyme guanylate kinase, also called GMP ... |
6-185 |
3.58e-115 |
|
guanylate kinase; Members of this family are the enzyme guanylate kinase, also called GMP kinase. This enzyme transfers a phosphate from ATP to GMP, yielding ADP and GDP. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 213788 Cd Length: 179 Bit Score: 325.22 E-value: 3.58e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 6 LYIVSAPSGAGKSSLIQAFLKTQPlyDSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTS 85
Cdd:TIGR03263 2 LIVISGPSGAGKSTLVKALLEEDP--NLKFSISATTRKPRPGEVDGVDYFFVSKEEFEEMIKAGEFLEWAEVHGNYYGTP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 86 RAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDY 165
Cdd:TIGR03263 80 KSPVEEALAAGKDVLLEIDVQGARQVKKKFPDAVSIFILPPSLEELERRLRKRGTDSEEVIERRLAKAKKEIAHADEFDY 159
|
170 180
....*....|....*....|
gi 506223188 166 LIVNDDFDAALADLKIILRA 185
Cdd:TIGR03263 160 VIVNDDLEKAVEELKSIILA 179
|
|
| Guanylate_kin |
pfam00625 |
Guanylate kinase; |
3-186 |
1.05e-84 |
|
Guanylate kinase;
Pssm-ID: 395500 Cd Length: 182 Bit Score: 248.45 E-value: 1.05e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 3 QGTLYIVSAPSGAGKSSLIQAFLKTQPLYDSqVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYY 82
Cdd:pfam00625 1 SRRPVVLSGPSGVGKSHIKKALLSEYPDKFG-YSVPHTTRPPRKGEVDGKDYYFVSKEEMERDISANEFLEYAQFSGNMY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 83 GTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYaE 162
Cdd:pfam00625 80 GTSVETIEQIHEQGKIVILDVDPQGVKQLRKAELSPISVFIKPPSLKVLQRRLKGRGKEQEEKINKRMAAAEQEFQHY-E 158
|
170 180
....*....|....*....|....
gi 506223188 163 YDYLIVNDDFDAALADLKIILRAE 186
Cdd:pfam00625 159 FDVIIVNDDLEEAYKKLKEALEAE 182
|
|
| GMPK |
cd00071 |
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), ... |
6-180 |
5.34e-69 |
|
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine diphosphate (GDP). It plays an essential role in the biosynthesis of guanosine triphosphate (GTP). This enzyme is also important for the activation of some antiviral and anticancer agents, such as acyclovir, ganciclovir, carbovir, and thiopurines.
Pssm-ID: 238026 Cd Length: 137 Bit Score: 207.00 E-value: 5.34e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 6 LYIVSAPSGAGKSSLIQAFLKTQPLYdSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTS 85
Cdd:cd00071 1 LIVLSGPSGVGKSTLLKRLLEEFDPN-FGFSVSHTTRKPRPGEVDGVDYHFVSKEEFERLIENGEFLEWAEFHGNYYGTS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 86 RAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPskeeldrrlrgrgqdseeviakrmaqavaemshyaeyDY 165
Cdd:cd00071 80 KAAVEEALAEGKIVILEIDVQGARQVKKSYPDAVSIFILPP-------------------------------------DY 122
|
170
....*....|....*
gi 506223188 166 LIVNDDFDAALADLK 180
Cdd:cd00071 123 VIVNDDLEKAYEELK 137
|
|
| GuKc |
smart00072 |
Guanylate kinase homologues; Active enzymes catalyze ATP-dependent phosphorylation of GMP to ... |
13-187 |
7.72e-69 |
|
Guanylate kinase homologues; Active enzymes catalyze ATP-dependent phosphorylation of GMP to GDP. Structure resembles that of adenylate kinase. So-called membrane-associated guanylate kinase homologues (MAGUKs) do not possess guanylate kinase activities; instead at least some possess protein-binding functions.
Pssm-ID: 214504 [Multi-domain] Cd Length: 174 Bit Score: 207.92 E-value: 7.72e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 13 SGAGKSSLIQAFLKTQPLYdSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTSRAAIEQV 92
Cdd:smart00072 1 SGVGKGTLLAELIQEIPDA-FERVVSHTTRPPRPGEVNGVDYHFVSKEEFEDDIKSGLFLEWGEYEGNYYGTSKETIRQV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 93 LATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDF 172
Cdd:smart00072 80 AEKGKHCLLDIDPQGVKQLRKAQLYPIVIFIAPPSSEELERRLRQRGTETSERIQKRLAAAQKEAQEYHLFDYVIVNDDL 159
|
170
....*....|....*
gi 506223188 173 DAALADLKIILRAER 187
Cdd:smart00072 160 EDAYEELKEILEAEQ 174
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| gmk |
PRK00300 |
guanylate kinase; Provisional |
1-206 |
2.97e-135 |
|
guanylate kinase; Provisional
Pssm-ID: 234719 Cd Length: 205 Bit Score: 377.12 E-value: 2.97e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 1 MAQGTLYIVSAPSGAGKSSLIQAFLKTQPlyDSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGN 80
Cdd:PRK00300 2 MRRGLLIVLSGPSGAGKSTLVKALLERDP--NLQLSVSATTRAPRPGEVDGVDYFFVSKEEFEEMIENGEFLEWAEVFGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 81 YYGTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY 160
Cdd:PRK00300 80 YYGTPRSPVEEALAAGKDVLLEIDWQGARQVKKKMPDAVSIFILPPSLEELERRLRGRGTDSEEVIARRLAKAREEIAHA 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 506223188 161 AEYDYLIVNDDFDAALADLKIILRAERLRMSRQKQRHDALITKLLA 206
Cdd:PRK00300 160 SEYDYVIVNDDLDTALEELKAIIRAERLRRSRQQQRHAELIEELLA 205
|
|
| Gmk |
COG0194 |
Guanylate kinase [Nucleotide transport and metabolism]; |
3-194 |
8.55e-124 |
|
Guanylate kinase [Nucleotide transport and metabolism];
Pssm-ID: 439964 Cd Length: 190 Bit Score: 347.44 E-value: 8.55e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 3 QGTLYIVSAPSGAGKSSLIQAFLKTQPlyDSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYY 82
Cdd:COG0194 1 RGKLIVLSGPSGAGKTTLVKALLERDP--DLRFSVSATTRPPRPGEVDGVDYHFVSREEFERMIENGEFLEWAEVHGNYY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 83 GTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAE 162
Cdd:COG0194 79 GTPKAEVEEALAAGKDVLLEIDVQGARQVKKKFPDAVSIFILPPSLEELERRLRGRGTDSEEVIERRLAKAREELAHADE 158
|
170 180 190
....*....|....*....|....*....|..
gi 506223188 163 YDYLIVNDDFDAALADLKIILRAERLRMSRQK 194
Cdd:COG0194 159 FDYVVVNDDLDRAVEELKAIIRAERLRRERQA 190
|
|
| guanyl_kin |
TIGR03263 |
guanylate kinase; Members of this family are the enzyme guanylate kinase, also called GMP ... |
6-185 |
3.58e-115 |
|
guanylate kinase; Members of this family are the enzyme guanylate kinase, also called GMP kinase. This enzyme transfers a phosphate from ATP to GMP, yielding ADP and GDP. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 213788 Cd Length: 179 Bit Score: 325.22 E-value: 3.58e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 6 LYIVSAPSGAGKSSLIQAFLKTQPlyDSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTS 85
Cdd:TIGR03263 2 LIVISGPSGAGKSTLVKALLEEDP--NLKFSISATTRKPRPGEVDGVDYFFVSKEEFEEMIKAGEFLEWAEVHGNYYGTP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 86 RAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDY 165
Cdd:TIGR03263 80 KSPVEEALAAGKDVLLEIDVQGARQVKKKFPDAVSIFILPPSLEELERRLRKRGTDSEEVIERRLAKAKKEIAHADEFDY 159
|
170 180
....*....|....*....|
gi 506223188 166 LIVNDDFDAALADLKIILRA 185
Cdd:TIGR03263 160 VIVNDDLEKAVEELKSIILA 179
|
|
| Guanylate_kin |
pfam00625 |
Guanylate kinase; |
3-186 |
1.05e-84 |
|
Guanylate kinase;
Pssm-ID: 395500 Cd Length: 182 Bit Score: 248.45 E-value: 1.05e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 3 QGTLYIVSAPSGAGKSSLIQAFLKTQPLYDSqVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYY 82
Cdd:pfam00625 1 SRRPVVLSGPSGVGKSHIKKALLSEYPDKFG-YSVPHTTRPPRKGEVDGKDYYFVSKEEMERDISANEFLEYAQFSGNMY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 83 GTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYaE 162
Cdd:pfam00625 80 GTSVETIEQIHEQGKIVILDVDPQGVKQLRKAELSPISVFIKPPSLKVLQRRLKGRGKEQEEKINKRMAAAEQEFQHY-E 158
|
170 180
....*....|....*....|....
gi 506223188 163 YDYLIVNDDFDAALADLKIILRAE 186
Cdd:pfam00625 159 FDVIIVNDDLEEAYKKLKEALEAE 182
|
|
| GMPK |
cd00071 |
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), ... |
6-180 |
5.34e-69 |
|
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine diphosphate (GDP). It plays an essential role in the biosynthesis of guanosine triphosphate (GTP). This enzyme is also important for the activation of some antiviral and anticancer agents, such as acyclovir, ganciclovir, carbovir, and thiopurines.
Pssm-ID: 238026 Cd Length: 137 Bit Score: 207.00 E-value: 5.34e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 6 LYIVSAPSGAGKSSLIQAFLKTQPLYdSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTS 85
Cdd:cd00071 1 LIVLSGPSGVGKSTLLKRLLEEFDPN-FGFSVSHTTRKPRPGEVDGVDYHFVSKEEFERLIENGEFLEWAEFHGNYYGTS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 86 RAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPskeeldrrlrgrgqdseeviakrmaqavaemshyaeyDY 165
Cdd:cd00071 80 KAAVEEALAEGKIVILEIDVQGARQVKKSYPDAVSIFILPP-------------------------------------DY 122
|
170
....*....|....*
gi 506223188 166 LIVNDDFDAALADLK 180
Cdd:cd00071 123 VIVNDDLEKAYEELK 137
|
|
| GuKc |
smart00072 |
Guanylate kinase homologues; Active enzymes catalyze ATP-dependent phosphorylation of GMP to ... |
13-187 |
7.72e-69 |
|
Guanylate kinase homologues; Active enzymes catalyze ATP-dependent phosphorylation of GMP to GDP. Structure resembles that of adenylate kinase. So-called membrane-associated guanylate kinase homologues (MAGUKs) do not possess guanylate kinase activities; instead at least some possess protein-binding functions.
Pssm-ID: 214504 [Multi-domain] Cd Length: 174 Bit Score: 207.92 E-value: 7.72e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 13 SGAGKSSLIQAFLKTQPLYdSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTSRAAIEQV 92
Cdd:smart00072 1 SGVGKGTLLAELIQEIPDA-FERVVSHTTRPPRPGEVNGVDYHFVSKEEFEDDIKSGLFLEWGEYEGNYYGTSKETIRQV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 93 LATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDF 172
Cdd:smart00072 80 AEKGKHCLLDIDPQGVKQLRKAQLYPIVIFIAPPSSEELERRLRQRGTETSERIQKRLAAAQKEAQEYHLFDYVIVNDDL 159
|
170
....*....|....*
gi 506223188 173 DAALADLKIILRAER 187
Cdd:smart00072 160 EDAYEELKEILEAEQ 174
|
|
| gmk |
PRK14737 |
guanylate kinase; Provisional |
1-183 |
2.95e-59 |
|
guanylate kinase; Provisional
Pssm-ID: 173199 Cd Length: 186 Bit Score: 184.04 E-value: 2.95e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 1 MAQGTLYIVSAPSGAGKSSLIQAFLKTQPlyDSQVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGN 80
Cdd:PRK14737 1 KASPKLFIISSVAGGGKSTIIQALLEEHP--DFLFSISCTTRAPRPGDEEGKTYFFLTIEEFKKGIADGEFLEWAEVHDN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 81 YYGTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQAR-SIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSH 159
Cdd:PRK14737 79 YYGTPKAFIEDAFKEGRSAIMDIDVQGAKIIKEKFPERIvTIFIEPPSEEEWEERLIHRGTDSEESIEKRIENGIIELDE 158
|
170 180
....*....|....*....|....
gi 506223188 160 YAEYDYLIVNDDFDAALADLKIIL 183
Cdd:PRK14737 159 ANEFDYKIINDDLEDAIADLEAII 182
|
|
| gmk |
PRK14738 |
guanylate kinase; Provisional |
2-193 |
8.33e-54 |
|
guanylate kinase; Provisional
Pssm-ID: 237809 Cd Length: 206 Bit Score: 170.68 E-value: 8.33e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 2 AQGTLYIVSAPSGAGKSSLIQAFLKTQPLYDsqVSVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNY 81
Cdd:PRK14738 11 AKPLLVVISGPSGVGKDAVLARMRERKLPFH--FVVTATTRPKRPGEIDGVDYHFVTPEEFREMISQNELLEWAEVYGNY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 82 YGTSRAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYA 161
Cdd:PRK14738 89 YGVPKAPVRQALASGRDVIVKVDVQGAASIKRLVPEAVFIFLAPPSMDELTRRLELRRTESPEELERRLATAPLELEQLP 168
|
170 180 190
....*....|....*....|....*....|....
gi 506223188 162 EYDYLIVN--DDFDAALADLKIILRAERLRMSRQ 193
Cdd:PRK14738 169 EFDYVVVNpeDRLDEAVAQIMAIISAEKSRVHPR 202
|
|
| PLN02772 |
PLN02772 |
guanylate kinase |
8-183 |
5.45e-49 |
|
guanylate kinase
Pssm-ID: 215414 [Multi-domain] Cd Length: 398 Bit Score: 164.24 E-value: 5.45e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 8 IVSAPSGAGKSSLIQAFLKTQPlydSQV--SVSHTTRNPRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTS 85
Cdd:PLN02772 139 VISGPSGVGKGTLISMLMKEFP---SMFgfSVSHTTRAPREMEKDGVHYHFTERSVMEKEIKDGKFLEFASVHGNLYGTS 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 86 RAAIEQVLATGVDVFLDIDWQGARQIREKMPQARSIFILPPSKEELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAE--- 162
Cdd:PLN02772 216 IEAVEVVTDSGKRCILDIDVQGARSVRASSLEAIFIFICPPSMEELEKRLRARGTETEEQIQKRLRNAEAELEQGKSsgi 295
|
170 180
....*....|....*....|.
gi 506223188 163 YDYLIVNDDFDAALADLKIIL 183
Cdd:PLN02772 296 FDHILYNDNLEECYKNLKKLL 316
|
|
| PhnN |
COG3709 |
Ribose 1,5-bisphosphate kinase PhnN [Carbohydrate transport and metabolism]; |
1-189 |
1.60e-17 |
|
Ribose 1,5-bisphosphate kinase PhnN [Carbohydrate transport and metabolism];
Pssm-ID: 442923 Cd Length: 188 Bit Score: 76.77 E-value: 1.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 1 MAQGTLYIVSAPSGAGKSSLIQAfLKTQPLYDSQVSVSH---TtrnpRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEV 77
Cdd:COG3709 2 SGPGRLIYVVGPSGAGKDSLLAA-ARARLAADPRLVFARryiT----RPADAGGEDHDALSEAEFARRAAAGAFALHWQA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 78 FGNYYGTsRAAIEQVLATGVDVFLDidwqGAR----QIREKMPQARSIFI-LPPskEELDRRLRGRGQDSEEVIAKRMAQ 152
Cdd:COG3709 77 HGLRYGI-PAEIDAWLAAGRDVVVN----GSRavlpQARARYPRLLVVLItASP--EVLAQRLAARGRESAEEIEARLAR 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 506223188 153 AVAEMSHyAEYDYLIVND-DFDAALADLKIILRAERLR 189
Cdd:COG3709 150 AAEFLPD-GPDVLVIDNDgPLEDAGARLLALLRAARAR 186
|
|
| phosphon_PhnN |
TIGR02322 |
phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Members of this ... |
4-154 |
1.79e-12 |
|
phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Members of this family resemble PhnN of phosphonate utilization operons, where different such operons confer the ability to use somewhat different profiles of C-P bond-containing compounds (see ), including phosphites as well as phosphonates. PhnN in E. coli shows considerable homology to guanylate kinases (EC 2.7.4.8), and has actually been shown to act as a ribose 1,5-bisphosphokinase (PRPP forming). This suggests an analogous kinase reaction for phosphonate metabolism, converting 5-phosphoalpha-1-(methylphosphono)ribose to methylphosphono-PRPP. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 274078 Cd Length: 179 Bit Score: 63.15 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 4 GTLYIVSAPSGAGKSSLIQaFLKTQPLYDSQVSVSHTTRNpRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYG 83
Cdd:TIGR02322 1 GRLIYVVGPSGAGKDTLLD-YARARLAGDPRVHFVRRVIT-RPASAGGENHIALSTEEFDHREDGGAFALSWQAHGLSYG 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 506223188 84 TSrAAIEQVLATGVDVFLDidwqGAR----QIREKMPQARSIFILPPSkEELDRRLRGRGQDSEEVIAKRMAQAV 154
Cdd:TIGR02322 79 IP-IEIDQWLEAGDVVVVN----GSRavlpEARQRYPNLLVVNITASP-DVLAQRLAARGRESREEIEERLARSA 147
|
|
| PRK10078 |
PRK10078 |
ribose 1,5-bisphosphokinase; Provisional |
12-199 |
1.55e-09 |
|
ribose 1,5-bisphosphokinase; Provisional
Pssm-ID: 236648 Cd Length: 186 Bit Score: 55.14 E-value: 1.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 12 PSGAGKSSLIQAfLKTQPlyDSQVSVSHTTRNpRPGEVHGEHYYFVSHDQFRSMIAEDAFLEHAEVFGNYYGTSrAAIEQ 91
Cdd:PRK10078 10 PSGSGKDSLLAA-LRQRE--QTQLLVAHRYIT-RPASAGSENHIALSEQEFFTRAGQNLFALSWHANGLYYGVG-IEIDL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 92 VLATGVDVFLDidwqGARQireKMPQARSIF---ILP----PSKEELDRRLRGRGQDSEEVIAKRMAQAvaemSHYAEYD 164
Cdd:PRK10078 85 WLHAGFDVLVN----GSRA---HLPQARARYqsaLLPvclqVSPEILRQRLENRGRENASEINARLARA----ARYQPQD 153
|
170 180 190
....*....|....*....|....*....|....*..
gi 506223188 165 YLIVNDD--FDAALADLKIILRAErlrmsrQKQRHDA 199
Cdd:PRK10078 154 CHTLNNDgsLRQSVDTLLTLLHLS------QKEKHHA 184
|
|
| PRK12289 |
PRK12289 |
small ribosomal subunit biogenesis GTPase RsgA; |
8-42 |
3.71e-03 |
|
small ribosomal subunit biogenesis GTPase RsgA;
Pssm-ID: 237040 [Multi-domain] Cd Length: 352 Bit Score: 37.30 E-value: 3.71e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 506223188 8 IVSAPSGAGKSSLIQAFLktqPLYDSQVS-VS-------HTTR 42
Cdd:PRK12289 176 VVAGPSGVGKSSLINRLI---PDVELRVGkVSgklgrgrHTTR 215
|
|
| AAA_18 |
pfam13238 |
AAA domain; |
8-155 |
7.52e-03 |
|
AAA domain;
Pssm-ID: 433052 [Multi-domain] Cd Length: 128 Bit Score: 35.10 E-value: 7.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506223188 8 IVSAPSGAGKSSLIQAFLKTQPLYDSQVSVsHTTRNPRPGEvhgEHYYFVSH--DQFRSMIAEDAFLEHAEVFGNyygts 85
Cdd:pfam13238 2 LITGTPGVGKTTLAKELSKRLGFGDNVRDL-ALENGLVLGD---DPETRESKrlDEDKLDRLLDLLEENAALEEG----- 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 506223188 86 raaieqvlatGVDVfldIDWQGARQIREKMPQARSIFI-LPPskEELDRRLRGRGQDSEEVIAKRMAQAVA 155
Cdd:pfam13238 73 ----------GNLI---IDGHLAELEPERAKDLVGIVLrASP--EELLERLEKRGYEEAKIKENEEAEILG 128
|
|
| |
