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Conserved domains on  [gi|506258226|ref|WP_015778001|]
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nucleoside triphosphate pyrophosphatase [Anaerococcus prevotii]

Protein Classification

Maf family protein( domain architecture ID 10785471)

multicopy associated filamentation (Maf) family protein is involved in septum formation and also has a role as a house-cleaning NTP pyrophosphatase

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0009117|GO:0047429|GO:0009146|GO:0000166
PubMed:  24210219
SCOP:  4000520

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 17-210 7.36e-57

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440193  Cd Length: 189  Bit Score: 177.92  E-value: 7.36e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  17 KKYILMSKSPRRRDLLSFL--KPEIASIRIDERAIEEkymekykdcdfiERAGKTCAEIAKAKSD--VDLVKDCLYISSD 92
Cdd:COG0424    1 PKLILASASPRRRELLEQLglPFEVVPPDIDETPLPG------------ESPEELVLRLARAKAEavAARLPDALVLGAD 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  93 TMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNY-LDVFYSIAEVRFtdyyKEM-DEIIDGYLIEENVMD 170
Cdd:COG0424   69 TVVVLDGRILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGGrLWTRVVTTRVTF----RPLsDAEIEAYLATGEPLD 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 506258226 171 KAGAYGIQDLDPRLISYINGDINTIIGLPVSEVsRRILGE 210
Cdd:COG0424  145 KAGAYGIQGLGAALVERIEGSYSNVVGLPLIEL-LELLRE 183
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 17-210 7.36e-57

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 177.92  E-value: 7.36e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  17 KKYILMSKSPRRRDLLSFL--KPEIASIRIDERAIEEkymekykdcdfiERAGKTCAEIAKAKSD--VDLVKDCLYISSD 92
Cdd:COG0424    1 PKLILASASPRRRELLEQLglPFEVVPPDIDETPLPG------------ESPEELVLRLARAKAEavAARLPDALVLGAD 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  93 TMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNY-LDVFYSIAEVRFtdyyKEM-DEIIDGYLIEENVMD 170
Cdd:COG0424   69 TVVVLDGRILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGGrLWTRVVTTRVTF----RPLsDAEIEAYLATGEPLD 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 506258226 171 KAGAYGIQDLDPRLISYINGDINTIIGLPVSEVsRRILGE 210
Cdd:COG0424  145 KAGAYGIQGLGAALVERIEGSYSNVVGLPLIEL-LELLRE 183
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 20-205 1.45e-48

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 156.48  E-value: 1.45e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  20 ILMSKSPRRRDLLS--FLKPEIASIRIDERAIEEkymekykdcdfiERAGKTCAEIAKAKSDV---DLVKDCLYISSDTM 94
Cdd:cd00555    2 ILASASPRRRELLEqlGIPFEVVPSDIDETPIKG------------ESPEDYVLRLAEAKAEAvaaRLPPDALVIGADTV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  95 VILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCL-RSKNYLDVFYSIAEVRFtdyyKEM-DEIIDGYLIEENVMDKA 172
Cdd:cd00555   70 VVLDGRILGKPKDREEAREMLKRLSGRTHEVYTGVALiDPGGKLVTDVESTKVRF----RELsDEEIEAYVASGEPLDKA 145

                        170       180       190
                 ....*....|....*....|....*....|...
gi 506258226 173 GAYGIQDLDPRLISYINGDINTIIGLPVSEVSR 205
Cdd:cd00555  146 GAYGIQGLGGALIERIEGDYSNVVGLPLPELLK 178
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 20-205 6.11e-45

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 147.16  E-value: 6.11e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   20 ILMSKSPRRRDLLS--FLKPEIASIRIDERAIEEKymekykdcdfiERAGKTCAEIAKAKSDvDLVkdclyISSDTMVIL 97
Cdd:pfam02545   2 ILASASPRRRELLEqlGIEFEVVPSDIDETPLKED-----------PAPEEYVLRLARAKAE-ALV-----IGADTVVVL 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   98 ddkIYGKPRNMAEARDMFMSYFGKSHFVITGVCL---RSKNYLDVFYSIAEVRFtdyyKEM-DEIIDGYLIEENVMDKAG 173
Cdd:pfam02545  65 ---ILGKPKDEEEARAMLKRLSGRTHEVYTGVALinpGGGTGGVSFVETTRVTF----RPLsDEEIEAYVATGEPLDKAG 137

                         170       180       190
                  ....*....|....*....|....*....|..
gi 506258226  174 AYGIQDLDPRLISYINGDINTIIGLPVSEVSR 205
Cdd:pfam02545 138 AYGIQGLGAALVERIEGDYSNVVGLPLIELLR 169
PRK00648 PRK00648
Maf-like protein; Reviewed
 15-203 1.60e-37

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 128.87  E-value: 1.60e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  15 KYKKYILMSKSPRRRDLLSFLkpEIASIRIDERAIEEKYMekyKDCDFIERAGktcaEIAKAKSDV---DLVKDCLYISS 91
Cdd:PRK00648   1 MKYKIILASSSPRRKEILEGF--RIPFEVVPSPFVEESYP---YSLDPEEITL----ELARLKAEAvrsDLFPDELIITA 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  92 DTMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYykeMDEIIDGYLIEENVMDK 171
Cdd:PRK00648  72 DTIVWYDGKVLGKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFREL---SDEEIEYYIDTYKPLDK 148

                        170       180       190
                 ....*....|....*....|....*....|..
gi 506258226 172 AGAYGIQDLDPRLISYINGDINTIIGLPVSEV 203
Cdd:PRK00648 149 AGAYGIQEWGGLIVKKIEGSYYNVMGLPIQTL 180
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 17-202 1.58e-36

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 125.97  E-value: 1.58e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   17 KKYILMSKSPRRRDLLSFL--KPEIASIRIDERAIEEKYMEKYkdcdfIERAGKtcaeiAKAKSDVDLVKDCLYISSDTM 94
Cdd:TIGR00172   3 KELILASQSPRRKELLEELgiSFEQIVSEFDEKSLKTTSPREL-----VYRLAK-----EKAQAVAELLADALIIGADTV 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   95 VILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYykeMDEIIDGYLIEENVMDKAGA 174
Cdd:TIGR00172  73 VILDGEIYGKPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRAL---DPEEIEKYVESGEPLEKAGA 149

                         170       180
                  ....*....|....*....|....*...
gi 506258226  175 YGIQDLDPRLISYINGDINTIIGLPVSE 202
Cdd:TIGR00172 150 FGIEGFGAPLIKKIDGDYSNVVGLPLEK 177
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 17-210 7.36e-57

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 177.92  E-value: 7.36e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  17 KKYILMSKSPRRRDLLSFL--KPEIASIRIDERAIEEkymekykdcdfiERAGKTCAEIAKAKSD--VDLVKDCLYISSD 92
Cdd:COG0424    1 PKLILASASPRRRELLEQLglPFEVVPPDIDETPLPG------------ESPEELVLRLARAKAEavAARLPDALVLGAD 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  93 TMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNY-LDVFYSIAEVRFtdyyKEM-DEIIDGYLIEENVMD 170
Cdd:COG0424   69 TVVVLDGRILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGGrLWTRVVTTRVTF----RPLsDAEIEAYLATGEPLD 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 506258226 171 KAGAYGIQDLDPRLISYINGDINTIIGLPVSEVsRRILGE 210
Cdd:COG0424  145 KAGAYGIQGLGAALVERIEGSYSNVVGLPLIEL-LELLRE 183
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 20-205 1.45e-48

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 156.48  E-value: 1.45e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  20 ILMSKSPRRRDLLS--FLKPEIASIRIDERAIEEkymekykdcdfiERAGKTCAEIAKAKSDV---DLVKDCLYISSDTM 94
Cdd:cd00555    2 ILASASPRRRELLEqlGIPFEVVPSDIDETPIKG------------ESPEDYVLRLAEAKAEAvaaRLPPDALVIGADTV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  95 VILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCL-RSKNYLDVFYSIAEVRFtdyyKEM-DEIIDGYLIEENVMDKA 172
Cdd:cd00555   70 VVLDGRILGKPKDREEAREMLKRLSGRTHEVYTGVALiDPGGKLVTDVESTKVRF----RELsDEEIEAYVASGEPLDKA 145

                        170       180       190
                 ....*....|....*....|....*....|...
gi 506258226 173 GAYGIQDLDPRLISYINGDINTIIGLPVSEVSR 205
Cdd:cd00555  146 GAYGIQGLGGALIERIEGDYSNVVGLPLPELLK 178
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 20-205 6.11e-45

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 147.16  E-value: 6.11e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   20 ILMSKSPRRRDLLS--FLKPEIASIRIDERAIEEKymekykdcdfiERAGKTCAEIAKAKSDvDLVkdclyISSDTMVIL 97
Cdd:pfam02545   2 ILASASPRRRELLEqlGIEFEVVPSDIDETPLKED-----------PAPEEYVLRLARAKAE-ALV-----IGADTVVVL 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   98 ddkIYGKPRNMAEARDMFMSYFGKSHFVITGVCL---RSKNYLDVFYSIAEVRFtdyyKEM-DEIIDGYLIEENVMDKAG 173
Cdd:pfam02545  65 ---ILGKPKDEEEARAMLKRLSGRTHEVYTGVALinpGGGTGGVSFVETTRVTF----RPLsDEEIEAYVATGEPLDKAG 137

                         170       180       190
                  ....*....|....*....|....*....|..
gi 506258226  174 AYGIQDLDPRLISYINGDINTIIGLPVSEVSR 205
Cdd:pfam02545 138 AYGIQGLGAALVERIEGDYSNVVGLPLIELLR 169
PRK00648 PRK00648
Maf-like protein; Reviewed
 15-203 1.60e-37

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 128.87  E-value: 1.60e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  15 KYKKYILMSKSPRRRDLLSFLkpEIASIRIDERAIEEKYMekyKDCDFIERAGktcaEIAKAKSDV---DLVKDCLYISS 91
Cdd:PRK00648   1 MKYKIILASSSPRRKEILEGF--RIPFEVVPSPFVEESYP---YSLDPEEITL----ELARLKAEAvrsDLFPDELIITA 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  92 DTMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYykeMDEIIDGYLIEENVMDK 171
Cdd:PRK00648  72 DTIVWYDGKVLGKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFREL---SDEEIEYYIDTYKPLDK 148

                        170       180       190
                 ....*....|....*....|....*....|..
gi 506258226 172 AGAYGIQDLDPRLISYINGDINTIIGLPVSEV 203
Cdd:PRK00648 149 AGAYGIQEWGGLIVKKIEGSYYNVMGLPIQTL 180
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 17-202 1.58e-36

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 125.97  E-value: 1.58e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   17 KKYILMSKSPRRRDLLSFL--KPEIASIRIDERAIEEKYMEKYkdcdfIERAGKtcaeiAKAKSDVDLVKDCLYISSDTM 94
Cdd:TIGR00172   3 KELILASQSPRRKELLEELgiSFEQIVSEFDEKSLKTTSPREL-----VYRLAK-----EKAQAVAELLADALIIGADTV 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226   95 VILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYykeMDEIIDGYLIEENVMDKAGA 174
Cdd:TIGR00172  73 VILDGEIYGKPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRAL---DPEEIEKYVESGEPLEKAGA 149

                         170       180
                  ....*....|....*....|....*...
gi 506258226  175 YGIQDLDPRLISYINGDINTIIGLPVSE 202
Cdd:TIGR00172 150 FGIEGFGAPLIKKIDGDYSNVVGLPLEK 177
PRK14363 PRK14363
Maf-like protein; Provisional
 18-203 4.43e-32

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 115.38  E-value: 4.43e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  18 KYILMSKSPRRRDLLSFLKPEIASIRIDeraIEEKymekykdcdFIERAGKTCAEIAKAKS----DVDLVKDCLYISSDT 93
Cdd:PRK14363   2 RIILASSSPRRRQLMELLGIEFEVEKPD---VEEE---------FLESPEETVRELSLRKAewvfKKRKEEEILVIGSDT 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  94 MVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYykeMDEIIDGYLIEENVMDKAG 173
Cdd:PRK14363  70 VVVLDGNILGKPESLEEAKGMLKKLSGRWHVVYTGVAFVSSETKDVIVSSTKVRFREL---PESVIDYYVEKYRPLDKAG 146

                        170       180       190
                 ....*....|....*....|....*....|
gi 506258226 174 AYGIQDLDPRLISYINGDINTIIGLPVSEV 203
Cdd:PRK14363 147 AYGIQDFAAVFVEKIEGDFFTVVGFPLGMV 176
PRK14368 PRK14368
Maf-like protein; Provisional
 20-203 1.63e-23

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 92.53  E-value: 1.63e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  20 ILMSKSPRRRDLLsflkpEIASIRIDERA--IEEKYMEKYKDCDFIERAGKTCAEIAKAKSDVDLvkdclYISSDTMVIL 97
Cdd:PRK14368   8 VLASASPRRSELL-----ASAGIEFDVVPadIPEEPLPGEEPVDHVLRLAREKARAAAALAEGRF-----FIGADTIVVC 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  98 DDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYlDVFYSIAeVRFTDYYKEM-DEIIDGYLIEENVMDKAGAYG 176
Cdd:PRK14368  78 DGEIMGKPKDEADAVRMLKKLSGVPHEVITGFAVYDRER-DGCVTKA-VRTKVFFKPLrDEEIRDYIATGCPMDKAGAYA 155

                        170       180
                 ....*....|....*....|....*..
gi 506258226 177 IQDLDPRLISYINGDINTIIGLPVSEV 203
Cdd:PRK14368 156 IQGGAAHMVRKIDGSYTNVVGLPLCEV 182
PRK14362 PRK14362
Maf-like protein; Provisional
 20-208 9.66e-23

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 91.08  E-value: 9.66e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  20 ILMSKSPRRRDllsFLKPEIASIRIDER-AIEEKYMEKYKDCDFIERAGktcaeIAKAKSDVDLVKDCLYISSDTMVILD 98
Cdd:PRK14362  15 VLASGSPRRRE---FLEQMGLPFEVILPgAAEPSPIEGEQPEAYARRAA-----EAKARAVAADHAGRLVIAADTVVALD 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  99 DKIYGKPRNMAEARDMFMSYFGKSHFVITGVCL-RSKNYLDVFYSIAEVRFTDYykeMDEIIDGYLIEENVMDKAGAYGI 177
Cdd:PRK14362  87 GMILGKPADRADALSMLRRLAGRTHEVVSACCVvLPDGGREVFHAITRVTMWDW---PEAALAAYVATGEPSDKAGAYGI 163

                        170       180       190
                 ....*....|....*....|....*....|.
gi 506258226 178 QDLDPRLISYINGDINTIIGLPVSEVSRRIL 208
Cdd:PRK14362 164 QGIGAFLVRSIEGSWSNVVGLPVAELTALLL 194
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 20-148 2.16e-21

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 85.25  E-value: 2.16e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  20 ILMSKSPRRRDLLS---FLKPEIASIRIDERAIEEKymekykdcdfierAGKTCAEIAKAKSD--VDLVKDCLYISSDTM 94
Cdd:cd00985    2 ILASGSPRRLEELKqigGIEFEVLPSDIDETGLKGE-------------PEDTVEELALLKARavAERLPDAPVIADDTG 68

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 506258226  95 VILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCL-RSKNYLDVFYSIAEVRF 148
Cdd:cd00985   69 LVVDGRPGGKPARFAEALEMLRGLSGRTAEFVTAVALvDPDGKIITFEGETEGKI 123
PRK02478 PRK02478
Maf-like protein; Reviewed
 18-199 3.58e-21

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 86.71  E-value: 3.58e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  18 KYILMSKSPRRRDLL--SFLKPEIASIRIDERAIEEKymekykdcdfIERAGKTCAEIA------KAKSDVDLVKDCLYI 89
Cdd:PRK02478   4 KLILASKSPFRRALLenAGLEFSAAAADIDERAVEAP----------LEESGATPEDVAlvlaeaKAIDVSERFPGALVI 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  90 SSDTMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCL-RSKNYLDVFYSIAE--VRFTDyykemDEIIDGYLieE 166
Cdd:PRK02478  74 GCDQTMSLGDEVFHKPKDMEEARRHLQKLSGKTHQLNSAVVLvRDGKVLWRHVSIAHmtMRDLD-----AGFIGRHL--A 146

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 506258226 167 NVMDKA----GAYGIQDLDPRLISYINGDINTIIGLP 199
Cdd:PRK02478 147 RVGEKAlssvGAYQLEGEGIQLFEKIEGDYFTILGLP 183
PRK14364 PRK14364
Maf-like protein; Provisional
 21-205 9.43e-21

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 85.05  E-value: 9.43e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  21 LMSKSPRRRDLLSFL--KPEIASIRIDERAIEEKYMEKYkdcdfIERAGKTcaeiaKAKSDVDLVKDCLYISSDTMVILD 98
Cdd:PRK14364   1 LASSSPRRRELLQQLglNFEIYSPDIDESVHEGELVHQY-----VERLARE-----KAQAVLNIFPDSVIIAADTSLGLD 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  99 DKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYykEMDEIIDGYLIEENVmDKAGAYGIQ 178
Cdd:PRK14364  71 GQIIGKPDSKQHAFDIWKQLSGRWHDVFSGICIATQQQILSQVVQTQVEFASL--TTQDMEDYWATGEPV-GKAGAYAIQ 147

                        170       180
                 ....*....|....*....|....*..
gi 506258226 179 DLDPRLISYINGDINTIIGLPVSEVSR 205
Cdd:PRK14364 148 GIASQYIPKIQGSYSNVVGLPLYEFSQ 174
PRK00078 PRK00078
Maf-like protein; Reviewed
 17-200 1.49e-20

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 84.78  E-value: 1.49e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  17 KKYILMSKSPRRRDLLSFLKPEIASIRIDeraIEEKYMEKYKDCDfieragKTCAEIAKAKSDVDLVK----DCLYISSD 92
Cdd:PRK00078   1 MKIILASASERRQELLKRILEDFQVIVSD---FDESSVPFKGNIE------SYVMNLAEGKARSVSKKldqeSSIVIGCD 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  93 TMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCL--RSKNYLDVFYSIAEVRFTdyyKEMDEIIDGYLIEENVMD 170
Cdd:PRK00078  72 TIVAFNGKVLGKPKDEEDAFEMLKALSGNEHEVYSGIAIldTKSNKIIKDFVCTEVKFS---KLTDRQIRKYINTGEPMD 148

                        170       180       190
                 ....*....|....*....|....*....|
gi 506258226 171 KAGAYGIQDLDPRLISYINGDINTIIGLPV 200
Cdd:PRK00078 149 KAGAYGIQGKGGVFVEEINGCYYNVVGLPL 178
PRK14361 PRK14361
Maf-like protein; Provisional
 20-209 2.12e-18

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 79.20  E-value: 2.12e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  20 ILMSKSPRRRDLLsflkpeiASIRIDERAIEEKYMEKYKDCDfierAGKTCAEIA--KAKSDVDLVKDCLYISSDTMVIL 97
Cdd:PRK14361   2 ILASGSPRRRELL-------ENLGVPFQVVVSGEAEDSTETD----PARLAAELAllKARAVARLHPDAVVIAADTVVAL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  98 DDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVfysiaEVRFTD--YYKEMDEIIDGYLIEENVMDKAGAY 175
Cdd:PRK14361  71 GGVLLAKPADEAENEAFLRVLSGRTHQVYTGVAVLSRGTEQV-----GVERTDvtFRALTAAEISFYARSGEGLDKAGGY 145

                        170       180       190
                 ....*....|....*....|....*....|....
gi 506258226 176 GIQDLDPRLISYINGDINTIIGLPVSEVSRRILG 209
Cdd:PRK14361 146 GIQGVGMALVSRVEGDYSNVVGFPLSLVIRLLRG 179
PRK04694 PRK04694
Maf-like protein; Reviewed
 21-205 8.80e-18

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 77.69  E-value: 8.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  21 LMSKSPRRRDLLSFLKPEIASIRIDeraIEEKYMEKYKDCDFIERAGktcaeIAKAKSDVDLVK----DCLYISSDTMVI 96
Cdd:PRK04694   4 LASRSPRRRELLQRLDVPFQTLQLD---VPEVRAADESPDHYVQRVA-----LEKAHAGLALVQaadaDAIVLGSDTEVV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  97 LDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDV-FYSIAEVRFTdyyKEMDEIIDGYLIEENVMDKAGAY 175
Cdd:PRK04694  76 LGERVFGKPVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRAPAqALVVSEVTFD---LLDDAQIAAYAASGEPMGKAGAY 152

                        170       180       190
                 ....*....|....*....|....*....|
gi 506258226 176 GIQDLDPRLISYINGDINTIIGLPVSEVSR 205
Cdd:PRK04694 153 AIQGRAERFIRHLSGSYSGVMGLPLYQTSQ 182
PRK14365 PRK14365
Maf-like protein; Provisional
 17-200 1.04e-17

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 77.55  E-value: 1.04e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  17 KKYILMSKSPRRRDLLSFLKPEiaSIRIDERAIEEKYMEkykDCDFIERAGKTCAEIAKaksDVDL-VKDCLYISSDTMV 95
Cdd:PRK14365   2 RRIILASASPRRKELLKQLIGD--NFLVYPSSYEEPPQP---GLDPEELLLKHSLEKAR---DVAKhFDSGIIISADTSV 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  96 ILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSknyLDVFYSIAEVRFTD-YYKEMD-EIIDGYLIEENVMDKAG 173
Cdd:PRK14365  74 FCNGEVLGKPASPENAEEMLEKLSGRKFLVITGLTVLD---LDSGKEISEIESTDvWMTELSrEQILAYVRTGEPLDKAG 150

                        170       180
                 ....*....|....*....|....*..
gi 506258226 174 AYGIQDLDPRLISYINGDINTIIGLPV 200
Cdd:PRK14365 151 AFAIQGKGAVLVEKIEGDFFNVVGLPL 177
PRK14367 PRK14367
Maf-like protein; Provisional
 21-202 1.92e-16

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 74.33  E-value: 1.92e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  21 LMSKSPRRRDLLSFLKPEIASI--RIDE--RAIEEKYMEKYKDCDFIERAGKTC-AEIAKAKSDVDLvkdclyISSDTMV 95
Cdd:PRK14367   6 LGSNSPRRMEILTQLGYRVVKLpaGIDEtvKAGETPARYVQRMAEEKNRTALTLfCETNGTMPDFPL------ITADTCV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  96 ILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYYKEMdeiIDGYLIEENVMDKAGAY 175
Cdd:PRK14367  80 VSDGIILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEE---ISAYVQSGEPMDKAGAY 156

                        170       180
                 ....*....|....*....|....*..
gi 506258226 176 GIQDLDPRLISYINGDINTIIGLPVSE 202
Cdd:PRK14367 157 AVQGIGGIFIQSIEGSFSGIMGLPVYE 183
PRK01441 PRK01441
Maf-like protein; Reviewed
 17-210 3.70e-13

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 65.51  E-value: 3.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  17 KKYILMSKSPRRRDLLSFLKPEIASIR---IDEraiEEKYMEKYKDCDFIERAGKTCAEIAKAKSDVDLvKDCLYISSDT 93
Cdd:PRK01441   5 PKLVLASGSPRRVELLNQAGIEPDRLMpadIDE---TPKRAEHPRSLARRLSREKAEAALEALQGDDDW-RGAYILAADT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  94 MVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCL-------RSKnyldvfysIAE--VRFtdyyKEMDEI-IDGYL 163
Cdd:PRK01441  81 VVAVGRRILPKAELVDEASQCLRLLSGRNHRVYTGVCLvtpdgklRQK--------LVEtrVRF----KRLSREdIEAYL 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 506258226 164 IEENVMDKAGAYGIQDLDPRLISYINGDINTIIGLPVSEVSRRILGE 210
Cdd:PRK01441 149 ASGEWRGKAGGYAIQGIAGSFVVKLVGSYTNVVGLPLYETVSLLAGE 195
PRK14366 PRK14366
Maf-like protein; Provisional
 14-202 1.70e-12

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 63.28  E-value: 1.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  14 RKYKKYILMSKSPRRRDLLSFL--KP-EIASIRIDErAIEEKYMEKykdcDFIERAGKTCAEIAKAksdvdLVKDCLYIS 90
Cdd:PRK14366   2 LKFDNLILASSSKQRLALLEQIgvVPgEIVSPDIDE-SPLKKELPK----DYSIRMAKEKAEKVQS-----LRPDKFVLG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  91 SDTMVILDDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRS-KNYLDVFYSIAEVRFtdyyKEMDEI-IDGYLIEENV 168
Cdd:PRK14366  72 ADTVVCCGRRILLKAETEEQAEEYLELLSGRRHRVYTSVCLYTpGGKLHIRSVVTVVKF----KRLSKQeIKYYIASGEW 147

                        170       180       190
                 ....*....|....*....|....*....|....
gi 506258226 169 MDKAGAYGIQDLDPRLISYINGDINTIIGLPVSE 202
Cdd:PRK14366 148 KGKAGGCNIQGLAGKFVLSINGSYSSIIGLPLHE 181
PRK04056 PRK04056
septum formation inhibitor Maf;
20-200 1.86e-03

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 37.63  E-value: 1.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  20 ILMSKSPRRRDLLsflkpEIASIRIDERAIE--EKYMEKYKDCDFIERAGKTCAEIAKAKsdvdLVKDCLYISSDTMVIL 97
Cdd:PRK04056   3 ILASSSSTRANLL-----KEAGIEFEQKSLDfdEESIKKTSPKEFVYLAVKGKLEQFLKK----YGNECNLLVADSVVSC 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506258226  98 DDKIYGKPRNMAEARDMFMSYFGKSHFVITGVCLRSKNYLDVFYSIAEVRFTDYykEMDEiIDGYLIEENVMDKAGAYGI 177
Cdd:PRK04056  74 GNKILRKAKDKEEAREMLKLQSGNEISVLTCMILKSPEKEWLDLSVTTYRFKKF--DEDD-LEKYLESGLWQGKAGACMV 150

                        170       180
                 ....*....|....*....|...
gi 506258226 178 QDLDPRLISYINGDINTIIGLPV 200
Cdd:PRK04056 151 EGFHKKYIKSVSGNESTAMGLNV 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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