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Conserved domains on  [gi|506261551|ref|WP_015781326|]
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type II secretion system minor pseudopilin GspH [Kangiella koreensis]

Protein Classification

Tfp pilus assembly protein FimT/FimU( domain architecture ID 11471961)

Tfp pilus assembly protein FimT/FimU

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FimT COG4970
Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];
15-82 3.83e-16

Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];


:

Pssm-ID: 443996 [Multi-domain]  Cd Length: 73  Bit Score: 70.26  E-value: 3.83e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506261551  15 RHPITQAGFTLLEILIALAIAGIMLSVAVIAFSD-NDAAKLKNKAHQLFGLIQIAQEESIIRGIEVGIR 82
Cdd:COG4970    3 RLRRRQRGFTLIELLVVLAILAILAAIAVPSFSSlIARQRLRAAANELAAALRLARSEAIRRGQPVTLS 71
 
Name Accession Description Interval E-value
FimT COG4970
Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];
15-82 3.83e-16

Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];


Pssm-ID: 443996 [Multi-domain]  Cd Length: 73  Bit Score: 70.26  E-value: 3.83e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506261551  15 RHPITQAGFTLLEILIALAIAGIMLSVAVIAFSD-NDAAKLKNKAHQLFGLIQIAQEESIIRGIEVGIR 82
Cdd:COG4970    3 RLRRRQRGFTLIELLVVLAILAILAAIAVPSFSSlIARQRLRAAANELAAALRLARSEAIRRGQPVTLS 71
typeII_sec_gspH TIGR01708
type II secretion system protein H; This model represents GspH, protein H of the main terminal ...
 20-98 1.83e-12

type II secretion system protein H; This model represents GspH, protein H of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 130769 [Multi-domain]  Cd Length: 143  Bit Score: 62.20  E-value: 1.83e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506261551   20 QAGFTLLEILIALAIAGIMLSVAVIAFSDNDAAK-LKNKAHQLFGLIQIAQEESIIRGIEVGIRVEQDGYSFMIYDGTRW 98
Cdd:TIGR01708   3 QSGFTLIELLVVLAIMGLVAAAAALSLVSHYGTKsLDQVAGRLAARLRLAQTSARATGRPVLLRLGSRGIRFGERASLAL 82
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 20-43 8.77e-06

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 41.20  E-value: 8.77e-06
                          10        20
                  ....*....|....*....|....
gi 506261551   20 QAGFTLLEILIALAIAGIMLSVAV 43
Cdd:pfam07963   4 QRGFTLIELLVALAILAILLAAAL 27
T4P_ComGE NF041013
competence type IV pilus minor pilin ComGE;
22-95 1.01e-04

competence type IV pilus minor pilin ComGE;


Pssm-ID: 468942 [Multi-domain]  Cd Length: 83  Bit Score: 39.49  E-value: 1.01e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506261551  22 GFTLLEILIALAIAGIMLSVAVIAFS----DNDAAKLKNKAHQ-LFGLIQIAQEESIIRGIEvgIRVEQDGYSFMIYDG 95
Cdd:NF041013   5 GFILLESLVALALLALIVSLLLPSLTqiqkEREEIKQKEEALQvLYEALQTYQLHLELNGVE--ITVERSNTQIKVYWE 81
ComGD NF040982
competence type IV pilus minor pilin ComGD;
20-124 5.29e-04

competence type IV pilus minor pilin ComGD;


Pssm-ID: 468912 [Multi-domain]  Cd Length: 140  Bit Score: 38.76  E-value: 5.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506261551  20 QAGFTLLEILIALAIAGIMLSVAVIAFSDNDAAKLKNKA--HQLFGLIQIAQEESIIRGIEVGIRVEQDGYSFMIYDGTR 97
Cdd:NF040982   1 IKGFTLLESLLVLLIVSSLLLLTLSLSIPQTYEQVEEKLffEQFENDLLYAQQYAIASQQSTTITFSPDEIQYQFQEGGN 80

                         90       100
                 ....*....|....*....|....*...
gi 506261551  98 W-NPLQDHPLLRKVELDEPIEMYVNVEG 124
Cdd:NF040982  81 TsNRPYPLKIPISITVTKPNTITFNKNG 108
PRK10557 PRK10557
prepilin peptidase-dependent protein;
17-42 5.30e-04

prepilin peptidase-dependent protein;


Pssm-ID: 236714  Cd Length: 192  Bit Score: 39.58  E-value: 5.30e-04
                         10        20
                 ....*....|....*....|....*..
gi 506261551  17 PITQAGFTLLEILIALAIAG-IMLSVA 42
Cdd:PRK10557   3 PVKQRGFSLLEVLLAMAIGSvLLLGAA 29
 
Name Accession Description Interval E-value
FimT COG4970
Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];
15-82 3.83e-16

Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];


Pssm-ID: 443996 [Multi-domain]  Cd Length: 73  Bit Score: 70.26  E-value: 3.83e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506261551  15 RHPITQAGFTLLEILIALAIAGIMLSVAVIAFSD-NDAAKLKNKAHQLFGLIQIAQEESIIRGIEVGIR 82
Cdd:COG4970    3 RLRRRQRGFTLIELLVVLAILAILAAIAVPSFSSlIARQRLRAAANELAAALRLARSEAIRRGQPVTLS 71
typeII_sec_gspH TIGR01708
type II secretion system protein H; This model represents GspH, protein H of the main terminal ...
 20-98 1.83e-12

type II secretion system protein H; This model represents GspH, protein H of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 130769 [Multi-domain]  Cd Length: 143  Bit Score: 62.20  E-value: 1.83e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506261551   20 QAGFTLLEILIALAIAGIMLSVAVIAFSDNDAAK-LKNKAHQLFGLIQIAQEESIIRGIEVGIRVEQDGYSFMIYDGTRW 98
Cdd:TIGR01708   3 QSGFTLIELLVVLAIMGLVAAAAALSLVSHYGTKsLDQVAGRLAARLRLAQTSARATGRPVLLRLGSRGIRFGERASLAL 82
PulG COG2165
Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, ...
 20-71 3.34e-08

Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 441768 [Multi-domain]  Cd Length: 99  Bit Score: 49.91  E-value: 3.34e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 506261551  20 QAGFTLLEILIALAIAGIMLSVAVIAFSDNDAAKLKNKAHQLFGLIQIAQEE 71
Cdd:COG2165   10 QRGFTLIELLVVIAIIGILAALALPALQGARERARRAELRSNLRQIQQALER 61
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 20-43 8.77e-06

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 41.20  E-value: 8.77e-06
                          10        20
                  ....*....|....*....|....
gi 506261551   20 QAGFTLLEILIALAIAGIMLSVAV 43
Cdd:pfam07963   4 QRGFTLIELLVALAILAILLAAAL 27
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 15-47 9.80e-06

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 43.47  E-value: 9.80e-06
                         10        20        30
                 ....*....|....*....|....*....|...
gi 506261551  15 RHPITQAGFTLLEILIALAIAGIMLSVAVIAFS 47
Cdd:COG4795    3 RARRRQRGFTLLELLVALAIFALLLLAAYRGLD 35
IV_pilin_GFxxxE TIGR02532
prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all ...
 20-43 1.18e-05

prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all examples of the N-terminal region of bacterial proteins that resemble type IV pilins at their N-terminus, with a cleavage site G^FxxxE followed by a hydrophobic stretch. The new N-terminal residue, usually Phe, is methylated. Separate domains of the prepilin peptidase appear responsible for cleavage and methylation. Proteins with this N-terminal region include type IV pilins and other components of pilus biogenesis, competence proteins, and type II secretion proteins. Typically several proteins in a single operon have this N-terminal domain. The N-terminal cleavage and methylation site is described by PROSITE motif PS00409 as [KRHEQSTAG]-G-[FYLIVM]-[ST]-[LT]-[LIVP]-E-[LIVMFWSTAG](14). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274182 [Multi-domain]  Cd Length: 24  Bit Score: 40.75  E-value: 1.18e-05
                          10        20
                  ....*....|....*....|....
gi 506261551   20 QAGFTLLEILIALAIAGIMLSVAV 43
Cdd:TIGR02532   1 QRGFTLIELLVVLAILGILALIAL 24
PilE COG4968
Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];
20-48 1.25e-05

Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];


Pssm-ID: 443994 [Multi-domain]  Cd Length: 124  Bit Score: 43.14  E-value: 1.25e-05
                         10        20
                 ....*....|....*....|....*....
gi 506261551  20 QAGFTLLEILIALAIAGIMLSVAVIAFSD 48
Cdd:COG4968    9 QRGFTLIELMIVVAIIGILAAIAIPSYQD 37
PilW COG4966
Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];
20-49 7.95e-05

Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];


Pssm-ID: 443992 [Multi-domain]  Cd Length: 158  Bit Score: 41.70  E-value: 7.95e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 506261551  20 QAGFTLLEILIALAIAGIMLSVAVIAFSDN 49
Cdd:COG4966    4 QRGFTLVELMVALAIGLIVLAAVLQLFLSS 33
T4P_ComGE NF041013
competence type IV pilus minor pilin ComGE;
22-95 1.01e-04

competence type IV pilus minor pilin ComGE;


Pssm-ID: 468942 [Multi-domain]  Cd Length: 83  Bit Score: 39.49  E-value: 1.01e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506261551  22 GFTLLEILIALAIAGIMLSVAVIAFS----DNDAAKLKNKAHQ-LFGLIQIAQEESIIRGIEvgIRVEQDGYSFMIYDG 95
Cdd:NF041013   5 GFILLESLVALALLALIVSLLLPSLTqiqkEREEIKQKEEALQvLYEALQTYQLHLELNGVE--ITVERSNTQIKVYWE 81
PilV COG4967
Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];
12-61 1.97e-04

Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];


Pssm-ID: 443993 [Multi-domain]  Cd Length: 86  Bit Score: 38.81  E-value: 1.97e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 506261551  12 QSFRHPITQAGFTLLEILIALAIAGI-MLSVA---VIAFSDNDAAKLKNKAHQL 61
Cdd:COG4967    2 SRRRRRRRQRGFTLIEVLVALVILSIgLLGLAglqAASLRSSQDARQRTQAALL 55
ComGC COG4537
Competence protein ComGC [Mobilome: prophages, transposons];
20-69 3.87e-04

Competence protein ComGC [Mobilome: prophages, transposons];


Pssm-ID: 443603 [Multi-domain]  Cd Length: 108  Bit Score: 38.75  E-value: 3.87e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 506261551  20 QAGFTLLEILIALAIAGIMLSVAVIAFSDNdAAKLKNKAHQlfGLIQIAQ 69
Cdd:COG4537   11 EKGFTLIEMLIVLLIISILLLIAVPNLTKQ-RETAQEKGCE--ANIKMVQ 57
ComGD NF040982
competence type IV pilus minor pilin ComGD;
20-124 5.29e-04

competence type IV pilus minor pilin ComGD;


Pssm-ID: 468912 [Multi-domain]  Cd Length: 140  Bit Score: 38.76  E-value: 5.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506261551  20 QAGFTLLEILIALAIAGIMLSVAVIAFSDNDAAKLKNKA--HQLFGLIQIAQEESIIRGIEVGIRVEQDGYSFMIYDGTR 97
Cdd:NF040982   1 IKGFTLLESLLVLLIVSSLLLLTLSLSIPQTYEQVEEKLffEQFENDLLYAQQYAIASQQSTTITFSPDEIQYQFQEGGN 80

                         90       100
                 ....*....|....*....|....*...
gi 506261551  98 W-NPLQDHPLLRKVELDEPIEMYVNVEG 124
Cdd:NF040982  81 TsNRPYPLKIPISITVTKPNTITFNKNG 108
PRK10557 PRK10557
prepilin peptidase-dependent protein;
17-42 5.30e-04

prepilin peptidase-dependent protein;


Pssm-ID: 236714  Cd Length: 192  Bit Score: 39.58  E-value: 5.30e-04
                         10        20
                 ....*....|....*....|....*..
gi 506261551  17 PITQAGFTLLEILIALAIAG-IMLSVA 42
Cdd:PRK10557   3 PVKQRGFSLLEVLLAMAIGSvLLLGAA 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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