|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
1-243 |
0e+00 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 536.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 1 MSEIIYGIHAVKALLERDPQRFLEVFVLKGRDDRRLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKEGRKY 80
Cdd:PRK11181 1 MSEIIYGIHAVQALLERAPERFIEVFVLKGREDKRLLPLINELEAQGIVIQLANRQTLDEKAEGAVHQGIIARVKPGRQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 81 QENDLPALLDNLETPFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLART 160
Cdd:PRK11181 81 QENDLPDLLASLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLART 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 161 MRLLQERNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVR 240
Cdd:PRK11181 161 MRMLQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVR 240
|
...
gi 506321810 241 QRA 243
Cdd:PRK11181 241 QRS 243
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
2-242 |
2.02e-117 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 334.70 E-value: 2.02e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 2 SEIIYGIHAVKALLERDPQrfleVFVLKGRDDRRLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKEGRKYQ 81
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQR----VFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPILYKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 82 ENDLPALLDNLETPFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTM 161
Cdd:TIGR00186 77 LNDLYKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 162 RLLQERNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQ 241
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
.
gi 506321810 242 R 242
Cdd:TIGR00186 237 R 237
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
4-243 |
5.09e-106 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 307.12 E-value: 5.09e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 4 IIYGIHAVKALLERdPQRFLEVFVLKGRDDRrLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVkegRKYQEN 83
Cdd:COG0566 28 LAEGRHAVEEALKA-GREIEELLVTEGALDR-LAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVV---RPPEYA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 84 DLPALLDNL-ETPFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMR 162
Cdd:COG0566 103 DLEDLLAEAgEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNLADALE 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 163 LLQERNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQR 242
Cdd:COG0566 183 ELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYEAARQR 262
|
.
gi 506321810 243 A 243
Cdd:COG0566 263 R 263
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
96-238 |
1.41e-84 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 248.07 E-value: 1.41e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVGTA 175
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506321810 176 GEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
95-236 |
6.07e-53 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 167.71 E-value: 6.07e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 95 PFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQL-NATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVG 173
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPyNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506321810 174 TAGEADHtLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLF 236
Cdd:pfam00588 81 TSLGGKS-LYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
5-76 |
5.73e-18 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 75.27 E-value: 5.73e-18
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 506321810 5 IYGIHAVKALLERdPQRFLEVFVLKGRDDRrLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKE 76
Cdd:smart00967 1 IEGRHAVEEALKS-GRRIKELYLTEGRAER-LKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
1-243 |
0e+00 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 536.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 1 MSEIIYGIHAVKALLERDPQRFLEVFVLKGRDDRRLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKEGRKY 80
Cdd:PRK11181 1 MSEIIYGIHAVQALLERAPERFIEVFVLKGREDKRLLPLINELEAQGIVIQLANRQTLDEKAEGAVHQGIIARVKPGRQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 81 QENDLPALLDNLETPFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLART 160
Cdd:PRK11181 81 QENDLPDLLASLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLART 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 161 MRLLQERNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVR 240
Cdd:PRK11181 161 MRMLQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVR 240
|
...
gi 506321810 241 QRA 243
Cdd:PRK11181 241 QRS 243
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
2-242 |
2.02e-117 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 334.70 E-value: 2.02e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 2 SEIIYGIHAVKALLERDPQrfleVFVLKGRDDRRLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKEGRKYQ 81
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQR----VFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPILYKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 82 ENDLPALLDNLETPFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTM 161
Cdd:TIGR00186 77 LNDLYKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 162 RLLQERNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQ 241
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
.
gi 506321810 242 R 242
Cdd:TIGR00186 237 R 237
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
4-243 |
5.09e-106 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 307.12 E-value: 5.09e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 4 IIYGIHAVKALLERdPQRFLEVFVLKGRDDRrLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVkegRKYQEN 83
Cdd:COG0566 28 LAEGRHAVEEALKA-GREIEELLVTEGALDR-LAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVV---RPPEYA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 84 DLPALLDNL-ETPFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMR 162
Cdd:COG0566 103 DLEDLLAEAgEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNLADALE 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 163 LLQERNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQR 242
Cdd:COG0566 183 ELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYEAARQR 262
|
.
gi 506321810 243 A 243
Cdd:COG0566 263 R 263
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
96-238 |
1.41e-84 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 248.07 E-value: 1.41e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVGTA 175
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506321810 176 GEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
96-238 |
1.91e-53 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 169.14 E-value: 1.91e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVGTA 175
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506321810 176 GEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
95-236 |
6.07e-53 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 167.71 E-value: 6.07e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 95 PFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQL-NATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVG 173
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPyNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506321810 174 TAGEADHtLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLF 236
Cdd:pfam00588 81 TSLGGKS-LYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
96-242 |
7.54e-44 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 144.65 E-value: 7.54e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNlARTMRLLQERNIWIVGTA 175
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEASS-EETLAWLKENKIRILATT 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 506321810 176 GEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQR 242
Cdd:cd18104 80 PKAEKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYEALRQR 146
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
98-238 |
1.05e-43 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 144.29 E-value: 1.05e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 98 LILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVGT-AG 176
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGLeLT 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 506321810 177 EADHTLYQSKL--TGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:cd18082 82 DGSIPLSEFKFkkPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
96-233 |
2.02e-41 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 138.81 E-value: 2.02e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMRLLQErNIW-IVGT 174
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKE-NGWkVVGT 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 506321810 175 AGEAD----------HTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGS-----VSSLNVSVATGV 233
Cdd:cd18105 80 SAPPSassdkktipaNELSELLLEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaenpgVDSLNVSVAAGI 153
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
94-242 |
4.62e-36 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 125.27 E-value: 4.62e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 94 TPFL-LILDGVTDPHNLGACLRNADGAGVHAV-IVPRDRSAQLNatvKKVACGAAETVPVISVTNLARTMRLLQERNIWI 171
Cdd:cd18092 14 TRDLtVVLENVHDPHNASAVLRTCDAFGVQDVhVIEPKNKFKKN---RGVAMGADKWLDVHRHDSTEECLAALKEQGYRI 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 506321810 172 VGTA-GEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQR 242
Cdd:cd18092 91 VATSlSPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
98-238 |
1.82e-30 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 110.35 E-value: 1.82e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 98 LILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVG--TA 175
Cdd:cd18097 3 VVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIAleTT 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506321810 176 GEAdHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:cd18097 83 ENS-VPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
96-238 |
1.75e-27 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 102.85 E-value: 1.75e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAVIVPrDRSAQL-NATVKKVACGAAETVPVISVTNLARTMRLLQER-----NI 169
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVT-GHAADVyDPKTIRASTGSLFSLPIVRVPSNRELEDWVEARkargtPL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506321810 170 WIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:cd18107 80 QLVGTDEHGDHQIADHDFTRPTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLYEA 148
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
5-243 |
9.91e-24 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 97.54 E-value: 9.91e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 5 IYGIHAVKALLERDPQR-----FLEVFVLKGRDDRRLqpviaeLEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKegrK 79
Cdd:PRK10864 111 VYGENACQALFQSRPEAivrawFIQSVTPRFKEALRW------MAANRKAYHVVDEAELTKASGTEHHGGVCFLIK---K 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 80 YQENDLPALL-DNLETPFLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKkVACGAAETVPVISVTNLA 158
Cdd:PRK10864 182 RNGTDVQQWLaQAGAQDCVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQDAALLESGAAIR-TAEGGAEHVQPITGDSFV 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 159 RTMRLLQERNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:PRK10864 261 DVLDDFRQAGYTIVTTSSHKGTPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEW 340
|
....*
gi 506321810 239 VRQRA 243
Cdd:PRK10864 341 WRQNK 345
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
4-76 |
6.90e-21 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 83.06 E-value: 6.90e-21
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 506321810 4 IIYGIHAVKALLERDPqRFLEVFVLKGRDDRRLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKE 76
Cdd:pfam08032 1 LIYGRHAVLEALKSGP-EIKKLYLTEGRRDPRLKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKP 72
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
96-237 |
2.87e-19 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 81.05 E-value: 2.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISvTNLARTMRLLQERNIwIVGTA 175
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIICSPDTVDPYNPKVVQASMGSIFRVQIHY-TDLPALLAELKKAFP-VYGAD 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 506321810 176 --GEAdhtLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVS-SLNVSVATGVCLFE 237
Cdd:cd18109 79 ldGEN---LYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKGAeSLNVAVATAILLSE 140
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
88-242 |
1.30e-18 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 81.58 E-value: 1.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 88 LLDNLETPFLLILDGVTDPHNLGACLRNADGAGVHAV--IVPRDRSAQLNATvkkvACGAAETVPVISVTNLARTMRLLQ 165
Cdd:PRK11081 12 MLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVhaVWPGSRMRTMGST----AAGSNSWVQVKTHRTIGDAVAHLK 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 166 ERNIWIVGTA--------GEADHTlyqskltGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFE 237
Cdd:PRK11081 88 GQGMQILATHlsdtavdfREIDYT-------RPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYE 160
|
....*
gi 506321810 238 AVRQR 242
Cdd:PRK11081 161 AQRQR 165
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
5-76 |
5.73e-18 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 75.27 E-value: 5.73e-18
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 506321810 5 IYGIHAVKALLERdPQRFLEVFVLKGRDDRrLQPVIAELEAQGIVIQVANRQWLDKQADDAVHQGIVAKVKE 76
Cdd:smart00967 1 IEGRHAVEEALKS-GRRIKELYLTEGRAER-LKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
98-238 |
3.95e-15 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 69.97 E-value: 3.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 98 LILDGVTDPHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGAAETVPVISVTNLARTMRLLQERNIWIVGTAGE 177
Cdd:cd18106 3 VICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKVFLADNNL 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 506321810 178 ADHTLYQSKLT-GPLALVMGAEGEGMRRLTREHCDEL----ISIPMAGSVSSLNVSVATGVCLFEA 238
Cdd:cd18106 83 PVQPYDSIDYCsGPIVLVIGGETHGVSPEAYKLAHSTggsrVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
96-237 |
1.41e-14 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 68.40 E-value: 1.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 96 FLLILDGVTDPHNLGACLRNADGAGVHAV-IVPRDRsaqLNATVKKvacGAAETVPVISVTNLARTMRLLQERNIWIVGT 174
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVhLVGRRK---FNPFGAM---GTDRHVKFRHFDTLAEAKEYLKERGIRLVGV 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 506321810 175 -AGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVS-SLNVSVATGVCLFE 237
Cdd:cd18096 75 eIVPGAEPIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGSGTaSLNVSVAASIVLHH 139
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
97-237 |
1.37e-11 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 60.57 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 97 LLILDGVTDPHNLGACLRNADGAGVHAVI-VPRDRSAQLNATVKKVACGAAETVPVIsVTNLARTMRLLQERNIWIVGTA 175
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIVlVDSDLATVADRRLLRASRGYVFSLPVV-LADREEAVAFLRDNDIPLMTLD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 506321810 176 geADHTLYQSKLTG---PLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFE 237
Cdd:cd18108 81 --ADGDVPVKELGDrpdRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
164-241 |
5.91e-11 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 58.62 E-value: 5.91e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 506321810 164 LQERNIWIVGTAGEadHTLYQSKLTGPLALVMGAEGEGMRR-LTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQ 241
Cdd:cd18094 68 LPPGRLFLFTTKGT--KPYTDFDFKPGDYLVFGRESTGLPEeILDAFPDRRLRIPMRPKVRSLNLSNSVAIVLYEALRQ 144
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
192-241 |
9.84e-09 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 52.73 E-value: 9.84e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 506321810 192 ALVMGAEGEGM-RRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEAVRQ 241
Cdd:COG0219 96 VLLFGRETAGLpEEVLAAPADQRLRIPMRPGVRSLNLSNAVAIVLYEALRQ 146
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
106-237 |
2.71e-08 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 51.34 E-value: 2.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 106 PHNLGACLRNADGAGVHAVIVPRDRSAQLNATVKKVACGA------AETVP-----------VISVTNLARTMRllqern 168
Cdd:cd18093 11 PGNIGAVARAMKNFGLSDLRLVNPRCDDPEEAARALASGAedvlenAKVYDtleealadcdlVVATTARPRGLR------ 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 506321810 169 iWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGmrrLTRE---HCDELISIPMAGSVSSLNVSVATGVCLFE 237
Cdd:cd18093 85 -RPLLTPRELAELLKEHAAGGKVALVFGREDSG---LTNEelaLCDLLVTIPTNPEYPSLNLAQAVAIVLYE 152
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
106-237 |
1.82e-07 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 49.07 E-value: 1.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506321810 106 PHNLGACLRNADGAGVHAVIVPrDRSAQLNATVKKVACGAAETVPVISVT--NLARTMRLLQERNIWIVG---TAGEADH 180
Cdd:cd18091 11 PPNLGGLCRTCEIFGVSKLVLP-NLAVVEDKQFKALSVSAEKWLPIEEVKpeDLLPYLKEKKQEGYTIVGleqTANSVSL 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 506321810 181 TLYQ-SKLTgplALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFE 237
Cdd:cd18091 90 HDFQfPKKT---VLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYE 144
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
189-237 |
1.18e-04 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 42.03 E-value: 1.18e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 506321810 189 GPLALVMGAEGEGmrrLTRE---HCDELISIPMAGSVSSLNVSVATGVCLFE 237
Cdd:COG0565 106 GKVALVFGRERSG---LTNEelaLCDALVTIPTNPEYPSLNLAQAVQVVAYE 154
|
|
| |
