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Conserved domains on  [gi|506350869|ref|WP_015870588|]
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helix-turn-helix domain-containing protein [Edwardsiella ictaluri]

Protein Classification

winged helix-turn-helix domain-containing protein( domain architecture ID 10008602)

winged helix-turn-helix (wHTH) domain-containing protein binds DNA and may function as a transcriptional regulator

CATH:  1.10.10.10
Gene Ontology:  GO:0003677
PubMed:  10473770|8831795|15808743
SCOP:  3000034

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4519 COG4519
Uncharacterized conserved protein [Function unknown];
1-94 2.91e-56

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443593  Cd Length: 96  Bit Score: 168.99  E-value: 2.91e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506350869   1 MEINPVFARRLYLCWLLAHkDKPNVPRLMQLTGWPRRTLQDVLKALPGMGVTLCFVEQGVRHNDGYYTLTDWGPLDAEWI 80
Cdd:COG4519    4 SKTNPSFYRRLYLAWLIDS-GRPNVPALMEATGMPRRTAQDTLKALPGLGIECEFVQDGVRNNDGYYRISDWGPIDRAWV 82

                         90
                 ....*....|....
gi 506350869  81 AQHADGLLACLDQP 94
Cdd:COG4519   83 AEHLAEIAAALGYP 96
 
Name Accession Description Interval E-value
COG4519 COG4519
Uncharacterized conserved protein [Function unknown];
1-94 2.91e-56

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443593  Cd Length: 96  Bit Score: 168.99  E-value: 2.91e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506350869   1 MEINPVFARRLYLCWLLAHkDKPNVPRLMQLTGWPRRTLQDVLKALPGMGVTLCFVEQGVRHNDGYYTLTDWGPLDAEWI 80
Cdd:COG4519    4 SKTNPSFYRRLYLAWLIDS-GRPNVPALMEATGMPRRTAQDTLKALPGLGIECEFVQDGVRNNDGYYRISDWGPIDRAWV 82

                         90
                 ....*....|....
gi 506350869  81 AQHADGLLACLDQP 94
Cdd:COG4519   83 AEHLAEIAAALGYP 96
HTH_43 pfam09904
Winged helix-turn helix; This family, found in various hypothetical prokaryotic proteins, is a ...
 2-91 1.13e-45

Winged helix-turn helix; This family, found in various hypothetical prokaryotic proteins, is a probable winged helix DNA-binding domain.


Pssm-ID: 430915  Cd Length: 89  Bit Score: 142.06  E-value: 1.13e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506350869    2 EINPVFARRLYLCWLLaHKDKPNVPRLMQLTGWPRRTLQDVLKALPGMGVTLCFVEQGVRHNDGYYTLTDWGPLDAEWIA 81
Cdd:pfam09904   1 KTKTSFYRRLYLAWLI-DSGQANVPKLMAATGMPRRTAQDTIKALPELGIECEFVQDGERNNAGYYRISDWGPINSAWVE 79

                          90
                  ....*....|
gi 506350869   82 QHADGLLACL 91
Cdd:pfam09904  80 EHLDEIKAAL 89
 
Name Accession Description Interval E-value
COG4519 COG4519
Uncharacterized conserved protein [Function unknown];
1-94 2.91e-56

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443593  Cd Length: 96  Bit Score: 168.99  E-value: 2.91e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506350869   1 MEINPVFARRLYLCWLLAHkDKPNVPRLMQLTGWPRRTLQDVLKALPGMGVTLCFVEQGVRHNDGYYTLTDWGPLDAEWI 80
Cdd:COG4519    4 SKTNPSFYRRLYLAWLIDS-GRPNVPALMEATGMPRRTAQDTLKALPGLGIECEFVQDGVRNNDGYYRISDWGPIDRAWV 82

                         90
                 ....*....|....
gi 506350869  81 AQHADGLLACLDQP 94
Cdd:COG4519   83 AEHLAEIAAALGYP 96
HTH_43 pfam09904
Winged helix-turn helix; This family, found in various hypothetical prokaryotic proteins, is a ...
 2-91 1.13e-45

Winged helix-turn helix; This family, found in various hypothetical prokaryotic proteins, is a probable winged helix DNA-binding domain.


Pssm-ID: 430915  Cd Length: 89  Bit Score: 142.06  E-value: 1.13e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 506350869    2 EINPVFARRLYLCWLLaHKDKPNVPRLMQLTGWPRRTLQDVLKALPGMGVTLCFVEQGVRHNDGYYTLTDWGPLDAEWIA 81
Cdd:pfam09904   1 KTKTSFYRRLYLAWLI-DSGQANVPKLMAATGMPRRTAQDTIKALPELGIECEFVQDGERNNAGYYRISDWGPINSAWVE 79

                          90
                  ....*....|
gi 506350869   82 QHADGLLACL 91
Cdd:pfam09904  80 EHLDEIKAAL 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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