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Conserved domains on  [gi|510898460|ref|WP_016230889|]
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MULTISPECIES: phage tail tape measure protein [Enterobacteriaceae]

Protein Classification

phage tail tape measure protein( domain architecture ID 11474537)

phage tail tape measure protein similar to Escherichia virus Lambda tape measure protein, also called minor tail protein H, which controls tail length by stopping tail tube protein polymerization

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tape_meas_lam_C super family cl36929
phage tail tape measure protein, lambda family; This model represents a relatively ...
 475-817 1.56e-80

phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]


The actual alignment was detected with superfamily member TIGR01541:

Pssm-ID: 273681 [Multi-domain]  Cd Length: 332  Bit Score: 262.85  E-value: 1.56e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  475 AHAAMLALETELRTLEKHSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIE 554
Cdd:TIGR01541   1 NQLLLLTQQIADRKLKKLNTADEKSLQSRSDEIIALIKLEKLLEEAEQKALEALKKLAEATASIRAQNKRQLDRFGLGDK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  555 HQKRLNELAQQAARFEQQQSAKQAAISAKargltdrqaqRESEEQRLREVYGDNPAALAKATSALKNTWSAEEQLRGSWM 634
Cdd:TIGR01541  81 QRERLDARLQIDRTFRKQQRDLNKAMTAK----------GLAGSDLYKEQLAAIKASLNEALAELHAYYAAEDALQGDWL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  635 AGMKSGWGEWAESATDSFSQVKNAATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSMLTEIFLKQAMVGIVGSIGSAIGG 714
Cdd:TIGR01541 151 AGARSGLADYGETATNVASATAQLATNAFGGMASNIAQMATTGKANFKSFAVSVLSDIADIIAKLAIAGLAQSIGSLIGG 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  715 AVGGGASASGGTAIQAAAANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATsRIGVGNLYRLMRGYAEGGYVGGAGSP 794
Cdd:TIGR01541 231 AASGGNSSSGAMASYGAAYVPNFAGGGYTAGGGKYEPSGVVHPGEFVFTKGAT-RIGEGNLYAIMRGYAGGGGVLGVVAA 309

                         330       340
                  ....*....|....*....|...
gi 510898460  795 AQMRRAEGINFNQNNHVVIQNDG 817
Cdd:TIGR01541 310 GSGGLGPNGMFGGETAISINNDG 332
TMP_2 pfam06791
Prophage tail length tape measure protein; This family represents a conserved region located ...
 55-257 4.79e-68

Prophage tail length tape measure protein; This family represents a conserved region located towards the N-terminal end of prophage tail length tape measure protein (TMP). TMP is important for assembly of phage tails and involved in tail length determination. Mutated forms TMP cause tail fibres to be shortened.


:

Pssm-ID: 429120  Cd Length: 205  Bit Score: 224.52  E-value: 4.79e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   55 AQKAGISVGQYKAAMRTLPAQFTDIATQLAGGQNPWLILLQQGGQVKDSFGGMIPMFRGLAGAITLPM--VGVTSLAVAT 132
Cdd:pfam06791   1 MEAAGKSAKQTAAAMRNLPAQFTDIATSLAGGQSPLTVLLQQGGQIKDMFGGIGPALKALGGYVLGLInpLTLAAAAAAV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  133 GALVYAWYQGDSTLSAFNKTLVLSGNQSGLTADRMLTLSRAGQAAGLTFNQARESLAALMNAGVRGGEQFDAINQSVARF 212
Cdd:pfam06791  81 GALALAYYKGAEEADAFNKALILTGNAAGTTASQLAAMAEAIAAAGGTQGAAAEALAALASTGKIGGEQLEGVIRAAARM 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 510898460  213 ASASGVEVDKVAEAFGKLTTDPTSGLMAMARQFRNVTAEQIAYVA 257
Cdd:pfam06791 161 EKATGQSVDETAKDFAKLADDPLKAALKLNEQYHFLTAATYEQIK 205
PTZ00121 super family cl31754
MAEBL; Provisional
 250-630 1.42e-06

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 1.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  250 AEQIAYVAQLQRSGDEAGALQAANDIATKGFDEQTRRLKENMGTLEtwADKTGKAFKSMWDAILDIGRPESSADML---A 326
Cdd:PTZ00121 1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE--AKKKAEEDKKKADELKKAAAAKKKADEAkkkA 1427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  327 SAQKAFDEADKKWQWYQSRSQRRGKTSSFRaNLQGAWDDRENARLGLAAATLQSDMEKAGELAAR-DRAEREASQLKYTG 405
Cdd:PTZ00121 1428 EEKKKADEAKKKAEEAKKADEAKKKAEEAK-KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaEEAKKKADEAKKAA 1506

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  406 EAQKAYERLQTPLDKYTARQ-KELNKALKDGKILQADYNTLMASAKKDYEstLKKPSGV-KVSAGERQEDRAHAAMLALE 483
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEaKKAEEAKKADEAKKAEEKKKADELKKAEE--LKKAEEKkKAEEAKKAEEDKNMALRKAE 1584

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  484 tELRTLEK---------HSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHE--------KETLEYKRQL 546
Cdd:PTZ00121 1585 -EAKKAEEarieevmklYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEkkkaeelkKAEEENKIKA 1663

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  547 AELGDKIEHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKntwSAE 626
Cdd:PTZ00121 1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKK---EAE 1740


                  ....
gi 510898460  627 EQLR 630
Cdd:PTZ00121 1741 EDKK 1744
 
Name Accession Description Interval E-value
tape_meas_lam_C TIGR01541
phage tail tape measure protein, lambda family; This model represents a relatively ...
 475-817 1.56e-80

phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273681 [Multi-domain]  Cd Length: 332  Bit Score: 262.85  E-value: 1.56e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  475 AHAAMLALETELRTLEKHSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIE 554
Cdd:TIGR01541   1 NQLLLLTQQIADRKLKKLNTADEKSLQSRSDEIIALIKLEKLLEEAEQKALEALKKLAEATASIRAQNKRQLDRFGLGDK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  555 HQKRLNELAQQAARFEQQQSAKQAAISAKargltdrqaqRESEEQRLREVYGDNPAALAKATSALKNTWSAEEQLRGSWM 634
Cdd:TIGR01541  81 QRERLDARLQIDRTFRKQQRDLNKAMTAK----------GLAGSDLYKEQLAAIKASLNEALAELHAYYAAEDALQGDWL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  635 AGMKSGWGEWAESATDSFSQVKNAATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSMLTEIFLKQAMVGIVGSIGSAIGG 714
Cdd:TIGR01541 151 AGARSGLADYGETATNVASATAQLATNAFGGMASNIAQMATTGKANFKSFAVSVLSDIADIIAKLAIAGLAQSIGSLIGG 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  715 AVGGGASASGGTAIQAAAANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATsRIGVGNLYRLMRGYAEGGYVGGAGSP 794
Cdd:TIGR01541 231 AASGGNSSSGAMASYGAAYVPNFAGGGYTAGGGKYEPSGVVHPGEFVFTKGAT-RIGEGNLYAIMRGYAGGGGVLGVVAA 309

                         330       340
                  ....*....|....*....|...
gi 510898460  795 AQMRRAEGINFNQNNHVVIQNDG 817
Cdd:TIGR01541 310 GSGGLGPNGMFGGETAISINNDG 332
TMP_2 pfam06791
Prophage tail length tape measure protein; This family represents a conserved region located ...
 55-257 4.79e-68

Prophage tail length tape measure protein; This family represents a conserved region located towards the N-terminal end of prophage tail length tape measure protein (TMP). TMP is important for assembly of phage tails and involved in tail length determination. Mutated forms TMP cause tail fibres to be shortened.


Pssm-ID: 429120  Cd Length: 205  Bit Score: 224.52  E-value: 4.79e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   55 AQKAGISVGQYKAAMRTLPAQFTDIATQLAGGQNPWLILLQQGGQVKDSFGGMIPMFRGLAGAITLPM--VGVTSLAVAT 132
Cdd:pfam06791   1 MEAAGKSAKQTAAAMRNLPAQFTDIATSLAGGQSPLTVLLQQGGQIKDMFGGIGPALKALGGYVLGLInpLTLAAAAAAV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  133 GALVYAWYQGDSTLSAFNKTLVLSGNQSGLTADRMLTLSRAGQAAGLTFNQARESLAALMNAGVRGGEQFDAINQSVARF 212
Cdd:pfam06791  81 GALALAYYKGAEEADAFNKALILTGNAAGTTASQLAAMAEAIAAAGGTQGAAAEALAALASTGKIGGEQLEGVIRAAARM 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 510898460  213 ASASGVEVDKVAEAFGKLTTDPTSGLMAMARQFRNVTAEQIAYVA 257
Cdd:pfam06791 161 EKATGQSVDETAKDFAKLADDPLKAALKLNEQYHFLTAATYEQIK 205
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
257-856 2.74e-22

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 102.38  E-value: 2.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 257 AQLQRSGDEAGALQAANDIATKGFDEQTRRLKENMGTLETWADKTGKAFKSMWDAILDIGRPESSADMLASAQKAFDEAD 336
Cdd:COG5281    3 ALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALAA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 337 KKWQWYQSRSQRRGKTSSFRANLQGAWDDRENARLGLAAATLQSDMEKAGELAARDRAEREASQLKYTGEAQKAYERLQT 416
Cdd:COG5281   83 ALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 417 PLDKYTARQKELNKALKDGKILQADYNTLMASAKKDYESTLKKPS--GVKVSAGERQEDRAHAAMLALETELRTLEKHSG 494
Cdd:COG5281  163 AAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAaaAAAAAAAEAAAAEAQALAAAALAEQAALAAASA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 495 VNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEHQKRLNELAQQAARFEQQQS 574
Cdd:COG5281  243 AAQALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAAAQ 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 575 AKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKNTWSAEEQLRGSWMAGMKSGWGEWAESATDSFSQ 654
Cdd:COG5281  323 ALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSATNVAAQ 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 655 VKNAATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSM---LTEIFLKQAMVGIVGSIgsaiggavgggasASGGTAIQAA 731
Cdd:COG5281  403 VAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIadaLANAALASAADALGGAL-------------AGALGGLFGG 469

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 732 AANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEAT---SRIGVGNLYRLMRGYAEGGYVGGAGSPAQMrraeGINFNQN 808
Cdd:COG5281  470 GGGAAAGAAVYAGALGPFASGGVVSGPTFFAMAGGAglmGEAGPEAIMPLARGADGRLGVAAAGGGGGA----AVVVNIT 545

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*...
gi 510898460 809 NHVVIQNDGPNGRAGPQLMKAVYEMARKGAQDELRLQLRDGGMLSGSG 856
Cdd:COG5281  546 TPDAAGFRRSQAQIAAQVARAVARGGRGLAAAAAAAGAADGGAGGGAA 593
Tape_meas_lam_C pfam09718
Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively ...
 631-706 2.19e-19

Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively well-conserved region near the C terminus of the tape measure protein of a lambda and related phage. The protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behaviour is attributed to proteins from distantly related or unrelated families in other phage.


Pssm-ID: 430770 [Multi-domain]  Cd Length: 76  Bit Score: 83.10  E-value: 2.19e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 510898460  631 GSWMAGMKSGWGEWAESATDSFSQVKNAATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSMLTEIFLKQAMVGIVG 706
Cdd:pfam09718   1 GDWTDGAKRALAEYAEEASNAAGQVEEAFTSAFSGMEDALVEFVTTGKLNFSDFADSIIADLARIAARQAITGPLA 76
PRK11281 PRK11281
mechanosensitive channel MscK;
376-609 2.25e-08

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 58.00  E-value: 2.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  376 ATLQSDMEKAGE-LAARDRAEREASQLKYT--------GEAQKAYERLQ--------TPLDKYTARQKE--LNKALKDGK 436
Cdd:PRK11281   59 KLVQQDLEQTLAlLDKIDRQKEETEQLKQQlaqapaklRQAQAELEALKddndeetrETLSTLSLRQLEsrLAQTLDQLQ 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  437 ILQAD---YNTLMASAKKdyestlkkpsgvkvsagerQEDRAHAAMLALET---ELRTLEKHSGVNEK-ISQQRRDLWEA 509
Cdd:PRK11281  139 NAQNDlaeYNSQLVSLQT-------------------QPERAQAALYANSQrlqQIRNLLKGGKVGGKaLRPSQRVLLQA 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  510 ENQYVVLkeaatkrQLSEQEKSLLAHEketleykrQLAELGdkiehQKRLNELAQQAARFEQQQSAKQAAISAKARGLTD 589
Cdd:PRK11281  200 EQALLNA-------QNDLQRKSLEGNT--------QLQDLL-----QKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSE 259

                         250       260
                  ....*....|....*....|
gi 510898460  590 RQAQrESEEQRLREVYGDNP 609
Cdd:PRK11281  260 KTVQ-EAQSQDEAARIQANP 278
PTZ00121 PTZ00121
MAEBL; Provisional
 250-630 1.42e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 1.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  250 AEQIAYVAQLQRSGDEAGALQAANDIATKGFDEQTRRLKENMGTLEtwADKTGKAFKSMWDAILDIGRPESSADML---A 326
Cdd:PTZ00121 1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE--AKKKAEEDKKKADELKKAAAAKKKADEAkkkA 1427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  327 SAQKAFDEADKKWQWYQSRSQRRGKTSSFRaNLQGAWDDRENARLGLAAATLQSDMEKAGELAAR-DRAEREASQLKYTG 405
Cdd:PTZ00121 1428 EEKKKADEAKKKAEEAKKADEAKKKAEEAK-KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaEEAKKKADEAKKAA 1506

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  406 EAQKAYERLQTPLDKYTARQ-KELNKALKDGKILQADYNTLMASAKKDYEstLKKPSGV-KVSAGERQEDRAHAAMLALE 483
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEaKKAEEAKKADEAKKAEEKKKADELKKAEE--LKKAEEKkKAEEAKKAEEDKNMALRKAE 1584

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  484 tELRTLEK---------HSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHE--------KETLEYKRQL 546
Cdd:PTZ00121 1585 -EAKKAEEarieevmklYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEkkkaeelkKAEEENKIKA 1663

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  547 AELGDKIEHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKntwSAE 626
Cdd:PTZ00121 1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKK---EAE 1740


                  ....
gi 510898460  627 EQLR 630
Cdd:PTZ00121 1741 EDKK 1744
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 325-614 1.35e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   325 LASAQKAFDEADKKwqwyqsRSQRRGKTSSFRANLQGAWDDRENARLGLAAATLQSD-MEKAGELAARDRAEREASQLKY 403
Cdd:TIGR02168  693 IAELEKALAELRKE------LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqLEERIAQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   404 TGEAQKAYERLQTPLDKYTARQKELNKALKdgkilQADYNTLMASAKKDYESTLKKPSGVKVSAGERQEDRAHAAMLALE 483
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKE-----ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   484 TELRTLEKHSGVNEKISQQRRDLWEAENQyvvlkeaatkrqLSEQEKSLLAhEKETLEYKRQLAELgDKIEHQKRLNELA 563
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEE------------LESELEALLN-ERASLEEALALLRS-ELEELSEELRELE 907

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 510898460   564 QQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAK 614
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA 958
 
Name Accession Description Interval E-value
tape_meas_lam_C TIGR01541
phage tail tape measure protein, lambda family; This model represents a relatively ...
 475-817 1.56e-80

phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273681 [Multi-domain]  Cd Length: 332  Bit Score: 262.85  E-value: 1.56e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  475 AHAAMLALETELRTLEKHSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIE 554
Cdd:TIGR01541   1 NQLLLLTQQIADRKLKKLNTADEKSLQSRSDEIIALIKLEKLLEEAEQKALEALKKLAEATASIRAQNKRQLDRFGLGDK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  555 HQKRLNELAQQAARFEQQQSAKQAAISAKargltdrqaqRESEEQRLREVYGDNPAALAKATSALKNTWSAEEQLRGSWM 634
Cdd:TIGR01541  81 QRERLDARLQIDRTFRKQQRDLNKAMTAK----------GLAGSDLYKEQLAAIKASLNEALAELHAYYAAEDALQGDWL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  635 AGMKSGWGEWAESATDSFSQVKNAATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSMLTEIFLKQAMVGIVGSIGSAIGG 714
Cdd:TIGR01541 151 AGARSGLADYGETATNVASATAQLATNAFGGMASNIAQMATTGKANFKSFAVSVLSDIADIIAKLAIAGLAQSIGSLIGG 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  715 AVGGGASASGGTAIQAAAANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATsRIGVGNLYRLMRGYAEGGYVGGAGSP 794
Cdd:TIGR01541 231 AASGGNSSSGAMASYGAAYVPNFAGGGYTAGGGKYEPSGVVHPGEFVFTKGAT-RIGEGNLYAIMRGYAGGGGVLGVVAA 309

                         330       340
                  ....*....|....*....|...
gi 510898460  795 AQMRRAEGINFNQNNHVVIQNDG 817
Cdd:TIGR01541 310 GSGGLGPNGMFGGETAISINNDG 332
TMP_2 pfam06791
Prophage tail length tape measure protein; This family represents a conserved region located ...
 55-257 4.79e-68

Prophage tail length tape measure protein; This family represents a conserved region located towards the N-terminal end of prophage tail length tape measure protein (TMP). TMP is important for assembly of phage tails and involved in tail length determination. Mutated forms TMP cause tail fibres to be shortened.


Pssm-ID: 429120  Cd Length: 205  Bit Score: 224.52  E-value: 4.79e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   55 AQKAGISVGQYKAAMRTLPAQFTDIATQLAGGQNPWLILLQQGGQVKDSFGGMIPMFRGLAGAITLPM--VGVTSLAVAT 132
Cdd:pfam06791   1 MEAAGKSAKQTAAAMRNLPAQFTDIATSLAGGQSPLTVLLQQGGQIKDMFGGIGPALKALGGYVLGLInpLTLAAAAAAV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  133 GALVYAWYQGDSTLSAFNKTLVLSGNQSGLTADRMLTLSRAGQAAGLTFNQARESLAALMNAGVRGGEQFDAINQSVARF 212
Cdd:pfam06791  81 GALALAYYKGAEEADAFNKALILTGNAAGTTASQLAAMAEAIAAAGGTQGAAAEALAALASTGKIGGEQLEGVIRAAARM 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 510898460  213 ASASGVEVDKVAEAFGKLTTDPTSGLMAMARQFRNVTAEQIAYVA 257
Cdd:pfam06791 161 EKATGQSVDETAKDFAKLADDPLKAALKLNEQYHFLTAATYEQIK 205
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
257-856 2.74e-22

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 102.38  E-value: 2.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 257 AQLQRSGDEAGALQAANDIATKGFDEQTRRLKENMGTLETWADKTGKAFKSMWDAILDIGRPESSADMLASAQKAFDEAD 336
Cdd:COG5281    3 ALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALAA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 337 KKWQWYQSRSQRRGKTSSFRANLQGAWDDRENARLGLAAATLQSDMEKAGELAARDRAEREASQLKYTGEAQKAYERLQT 416
Cdd:COG5281   83 ALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALAAA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 417 PLDKYTARQKELNKALKDGKILQADYNTLMASAKKDYESTLKKPS--GVKVSAGERQEDRAHAAMLALETELRTLEKHSG 494
Cdd:COG5281  163 AAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAaaAAAAAAAEAAAAEAQALAAAALAEQAALAAASA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 495 VNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEHQKRLNELAQQAARFEQQQS 574
Cdd:COG5281  243 AAQALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAAAQ 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 575 AKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKNTWSAEEQLRGSWMAGMKSGWGEWAESATDSFSQ 654
Cdd:COG5281  323 ALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSATNVAAQ 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 655 VKNAATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSM---LTEIFLKQAMVGIVGSIgsaiggavgggasASGGTAIQAA 731
Cdd:COG5281  403 VAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIadaLANAALASAADALGGAL-------------AGALGGLFGG 469

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 732 AANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEAT---SRIGVGNLYRLMRGYAEGGYVGGAGSPAQMrraeGINFNQN 808
Cdd:COG5281  470 GGGAAAGAAVYAGALGPFASGGVVSGPTFFAMAGGAglmGEAGPEAIMPLARGADGRLGVAAAGGGGGA----AVVVNIT 545

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*...
gi 510898460 809 NHVVIQNDGPNGRAGPQLMKAVYEMARKGAQDELRLQLRDGGMLSGSG 856
Cdd:COG5281  546 TPDAAGFRRSQAQIAAQVARAVARGGRGLAAAAAAAGAADGGAGGGAA 593
Tape_meas_lam_C pfam09718
Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively ...
 631-706 2.19e-19

Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively well-conserved region near the C terminus of the tape measure protein of a lambda and related phage. The protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behaviour is attributed to proteins from distantly related or unrelated families in other phage.


Pssm-ID: 430770 [Multi-domain]  Cd Length: 76  Bit Score: 83.10  E-value: 2.19e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 510898460  631 GSWMAGMKSGWGEWAESATDSFSQVKNAATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSMLTEIFLKQAMVGIVG 706
Cdd:pfam09718   1 GDWTDGAKRALAEYAEEASNAAGQVEEAFTSAFSGMEDALVEFVTTGKLNFSDFADSIIADLARIAARQAITGPLA 76
PRK11281 PRK11281
mechanosensitive channel MscK;
376-609 2.25e-08

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 58.00  E-value: 2.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  376 ATLQSDMEKAGE-LAARDRAEREASQLKYT--------GEAQKAYERLQ--------TPLDKYTARQKE--LNKALKDGK 436
Cdd:PRK11281   59 KLVQQDLEQTLAlLDKIDRQKEETEQLKQQlaqapaklRQAQAELEALKddndeetrETLSTLSLRQLEsrLAQTLDQLQ 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  437 ILQAD---YNTLMASAKKdyestlkkpsgvkvsagerQEDRAHAAMLALET---ELRTLEKHSGVNEK-ISQQRRDLWEA 509
Cdd:PRK11281  139 NAQNDlaeYNSQLVSLQT-------------------QPERAQAALYANSQrlqQIRNLLKGGKVGGKaLRPSQRVLLQA 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  510 ENQYVVLkeaatkrQLSEQEKSLLAHEketleykrQLAELGdkiehQKRLNELAQQAARFEQQQSAKQAAISAKARGLTD 589
Cdd:PRK11281  200 EQALLNA-------QNDLQRKSLEGNT--------QLQDLL-----QKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSE 259

                         250       260
                  ....*....|....*....|
gi 510898460  590 RQAQrESEEQRLREVYGDNP 609
Cdd:PRK11281  260 KTVQ-EAQSQDEAARIQANP 278
PTZ00121 PTZ00121
MAEBL; Provisional
 250-630 1.42e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 1.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  250 AEQIAYVAQLQRSGDEAGALQAANDIATKGFDEQTRRLKENMGTLEtwADKTGKAFKSMWDAILDIGRPESSADML---A 326
Cdd:PTZ00121 1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE--AKKKAEEDKKKADELKKAAAAKKKADEAkkkA 1427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  327 SAQKAFDEADKKWQWYQSRSQRRGKTSSFRaNLQGAWDDRENARLGLAAATLQSDMEKAGELAAR-DRAEREASQLKYTG 405
Cdd:PTZ00121 1428 EEKKKADEAKKKAEEAKKADEAKKKAEEAK-KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaEEAKKKADEAKKAA 1506

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  406 EAQKAYERLQTPLDKYTARQ-KELNKALKDGKILQADYNTLMASAKKDYEstLKKPSGV-KVSAGERQEDRAHAAMLALE 483
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEaKKAEEAKKADEAKKAEEKKKADELKKAEE--LKKAEEKkKAEEAKKAEEDKNMALRKAE 1584

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  484 tELRTLEK---------HSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHE--------KETLEYKRQL 546
Cdd:PTZ00121 1585 -EAKKAEEarieevmklYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEkkkaeelkKAEEENKIKA 1663

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  547 AELGDKIEHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKntwSAE 626
Cdd:PTZ00121 1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKK---EAE 1740


                  ....
gi 510898460  627 EQLR 630
Cdd:PTZ00121 1741 EDKK 1744
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 358-630 1.65e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   358 NLQGAWDDRENARLGLAAATLQSDMEKAGELAARDRAEREASQLKYTGEAQKAYERLQTPLDKYTARQKELNKALKDgki 437
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE--- 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   438 lQADYNTLMASAKKDYESTLKKPSGVKVSAG-ERQEDRAHAAMLALETELRTlekhsGVNEKISQQRRDLWEAENQyvvL 516
Cdd:TIGR02168  707 -LEELEEELEQLRKELEELSRQISALRKDLArLEAEVEQLEERIAQLSKELT-----ELEAEIEELEERLEEAEEE---L 777

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   517 KEAATKRQlsEQEKSLLAHEKETLEYKRQLAELgdkiehQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRES 596
Cdd:TIGR02168  778 AEAEAEIE--ELEAQIEQLKEELKALREALDEL------RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          250       260       270
                   ....*....|....*....|....*....|....
gi 510898460   597 EEQRlrevygdnpaaLAKATSALKNTWSAEEQLR 630
Cdd:TIGR02168  850 LSED-----------IESLAAEIEELEELIEELE 872
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 325-614 1.35e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   325 LASAQKAFDEADKKwqwyqsRSQRRGKTSSFRANLQGAWDDRENARLGLAAATLQSD-MEKAGELAARDRAEREASQLKY 403
Cdd:TIGR02168  693 IAELEKALAELRKE------LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqLEERIAQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   404 TGEAQKAYERLQTPLDKYTARQKELNKALKdgkilQADYNTLMASAKKDYESTLKKPSGVKVSAGERQEDRAHAAMLALE 483
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKE-----ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   484 TELRTLEKHSGVNEKISQQRRDLWEAENQyvvlkeaatkrqLSEQEKSLLAhEKETLEYKRQLAELgDKIEHQKRLNELA 563
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEE------------LESELEALLN-ERASLEEALALLRS-ELEELSEELRELE 907

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 510898460   564 QQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAK 614
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA 958
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
390-604 1.60e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 1.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 390 ARDRAEREASQL-KYtgeaQKAYERLQTPLDKYTARQKELNKALKDgkilQADYNTLMASAKKDYESTLKKPSGVKVSAG 468
Cdd:PRK03918 146 SREKVVRQILGLdDY----ENAYKNLGEVIKEIKRRIERLEKFIKR----TENIEELIKEKEKELEEVLREINEISSELP 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 469 ERQEDRAhaamlALETELRTLEKHSgvnEKISQQRRDLWEAENQYVVLKEaaTKRQLSEQEKSLLAHEKETLEYKRQLAE 548
Cdd:PRK03918 218 ELREELE-----KLEKEVKELEELK---EEIEELEKELESLEGSKRKLEE--KIRELEERIEELKKEIEELEEKVKELKE 287

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 510898460 549 LGDKIEHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREV 604
Cdd:PRK03918 288 LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEEL 343
PTZ00121 PTZ00121
MAEBL; Provisional
 326-600 2.07e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 2.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  326 ASAQKAFDEADKKWQWYQSRSQRRGKTSSFRANLQGAWDDRENARLglAAATLQSDMEKAGELAARDRAEREASQLKyTG 405
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKK--AAEAAKAEAEAAADEAEAAEEKAEAAEKK-KE 1374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  406 EAQKAYERLQTPLDKYTARQKELNKALKDGKilQADYNTLMASAKKDYESTLKKPSGVKvsAGERQEDRAHAAMLALETE 485
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKK--KADELKKAAAAKKKADEAKKKAEEKK--KADEAKKKAEEAKKADEAK 1450

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  486 LRTLEKHsgvnekisqqrrdlwEAENqyvvLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEHQKRLNELAQQ 565
Cdd:PTZ00121 1451 KKAEEAK---------------KAEE----AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 510898460  566 AARFEQQQSAKQAAISAKARGLTDRQAQRESEEQR 600
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 359-603 2.71e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.01  E-value: 2.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 359 LQGAWDDRENARLGLAAATLQSDMEKAGELAARDRAEREasqlkytgEAQKAYERLQTPLDKYTARQKELNKALKDgkiL 438
Cdd:COG1196  218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELE--------ELEAELAELEAELEELRLELEELELELEE---A 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 439 QADYNTLMASAKKDYEstlkkpsgvKVSAGERQEDRAHAAMLALETELRTLEKH-SGVNEKISQQRRDLWEAENQYVVLK 517
Cdd:COG1196  287 QAEEYELLAELARLEQ---------DIARLEERRRELEERLEELEEELAELEEElEELEEELEELEEELEEAEEELEEAE 357

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 518 EAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESE 597
Cdd:COG1196  358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437


                 ....*.
gi 510898460 598 EQRLRE 603
Cdd:COG1196  438 EEEEEA 443
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
473-630 1.40e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 1.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  473 DRAHAAMLALETELRTLEKHSGVNEKISQQRRDL------------WEAENQYVVLKE---------AATKRQLSEQEKS 531
Cdd:COG4913   238 ERAHEALEDAREQIELLEPIRELAERYAAARERLaeleylraalrlWFAQRRLELLEAeleelraelARLEAELERLEAR 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  532 LLAHEKETLEYKRQLAEL-GDKIEH--------QKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLR 602
Cdd:COG4913   318 LDALREELDELEAQIRGNgGDRLEQlereierlERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALE 397

                         170       180
                  ....*....|....*....|....*...
gi 510898460  603 EVYGDNPAALAKATSALKNTWSAEEQLR 630
Cdd:COG4913   398 EELEALEEALAEAEAALRDLRRELRELE 425
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
457-603 1.72e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.89  E-value: 1.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 457 LKKPSGVKVSAGERQEDRAHAAMLALETELRTL-EKHSGVNEKISQQRRDLWEAENQYvvlkeAATKRQLSEQEKSLLAH 535
Cdd:COG4372   18 LRPKTGILIAALSEQLRKALFELDKLQEELEQLrEELEQAREELEQLEEELEQARSEL-----EQLEEELEELNEQLQAA 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 510898460 536 EKETLEYKRQLAEL-GDKIEHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLRE 603
Cdd:COG4372   93 QAELAQAQEELESLqEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLES 161
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 377-603 2.22e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   377 TLQSDMEKAGELAARDRAEREASQLKYTG---EAQKAYERLQTPLDKYTARQKELNKALKDgkiLQADYNTLMAsakkdy 453
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELALLVLrleELREELEELQEELKEAEEELEELTAELQE---LEEKLEELRL------ 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   454 estlkkpsgvKVSAGERQEDRAHAAMLALETELRTLEKhsgvNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLL 533
Cdd:TIGR02168  275 ----------EVSELEEEIEELQKELYALANEISRLEQ----QKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   534 AHEKETLEYKRQLAELgdkiehQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLRE 603
Cdd:TIGR02168  341 ELEEKLEELKEELESL------EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 339-622 2.89e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 2.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   339 WQWYQSRSQRRGKTSSFRANLQgawddrENARLGLAAATLQSDMEKAGELAARDRAEREASQLKYTGEA-----QKAYER 413
Cdd:TIGR00618   92 RTLRCTRSHRKTEQPEQLYLEQ------KKGRGRILAAKKSETEEVIHDLLKLDYKTFTRVVLLPQGEFaqflkAKSKEK 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   414 LQT-----PLDKYT---ARQKELNKALKdGKI----LQADYNTLMASAKKDYESTLKKPSGVKVSAGERQEDRAHAAMLA 481
Cdd:TIGR00618  166 KELlmnlfPLDQYTqlaLMEFAKKKSLH-GKAelltLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAY 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   482 LETELRTLEKHSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEHQKRLNE 561
Cdd:TIGR00618  245 LTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRA 324

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 510898460   562 --------LAQQAARFEQQQSAKQAAISA---------KARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKNT 622
Cdd:TIGR00618  325 kllmkraaHVKQQSSIEEQRRLLQTLHSQeihirdaheVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKEL 402
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
257-634 3.77e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 3.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 257 AQLQRSGDEA-GALQAANDIatkgfDEQTRRLKENMGTLETWADKTGKAFKSMWDAILDI-GRPESSADMLASAQKAFDE 334
Cdd:PRK02224 335 VAAQAHNEEAeSLREDADDL-----EERAEELREEAAELESELEEAREAVEDRREEIEELeEEIEELRERFGDAPVDLGN 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 335 ADKKWQWYQS-RSQRRGKTSSFRANLQGAWDDRENARLGLAA----------------ATLQSDMEKAGELAARdRAERE 397
Cdd:PRK02224 410 AEDFLEELREeRDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvETIEEDRERVEELEAE-LEDLE 488

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 398 ASQlkytGEAQKAYERLQTpLDKYTARQKELNKALKDGKILQADYNTLMAsAKKDYESTLKKPSGVKVSAGERQEDRAHA 477
Cdd:PRK02224 489 EEV----EEVEERLERAED-LVEAEDRIERLEERREDLEELIAERRETIE-EKRERAEELRERAAELEAEAEEKREAAAE 562

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 478 AMLALETELRTL----EKHSGVNEKISQQRR---DLWEAENQYVVLKEAATKR-QLSEQEKsllaHEKETLEYKRQ-LAE 548
Cdd:PRK02224 563 AEEEAEEAREEVaelnSKLAELKERIESLERirtLLAAIADAEDEIERLREKReALAELND----ERRERLAEKRErKRE 638

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 549 LGDKIEhQKRLNELAQQAARFEQ---QQSAKQAAISAKARGLTDRQAQRESEEQRLREVYgDNPAALAKATSALKNTWSA 625
Cdd:PRK02224 639 LEAEFD-EARIEEAREDKERAEEyleQVEEKLDELREERDDLQAEIGAVENELEELEELR-ERREALENRVEALEALYDE 716


                 ....*....
gi 510898460 626 EEQLRGSWM 634
Cdd:PRK02224 717 AEELESMYG 725
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 464-603 6.35e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 6.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 464 KVSAGERQEDRAHAAMLALETELRTLEK-HSGVNEKISQQRRDLWEAENQyvvLKEAATKRQLSEqekslLAHEKETLey 542
Cdd:COG1579   32 ELAELEDELAALEARLEAAKTELEDLEKeIKRLELEIEEVEARIKKYEEQ---LGNVRNNKEYEA-----LQKEIESL-- 101

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 510898460 543 KRQLAELGDKI-EHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLRE 603
Cdd:COG1579  102 KRRISDLEDEIlELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 482-646 1.02e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   482 LETELRTLEKHSGVNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEH------ 555
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEElrlevs 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   556 ---------QKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRlREVYGDNPAAL-AKATSALKNTWSA 625
Cdd:TIGR02168  278 eleeeieelQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK-LDELAEELAELeEKLEELKEELESL 356

                          170       180
                   ....*....|....*....|...
gi 510898460   626 EEQL--RGSWMAGMKSGWGEWAE 646
Cdd:TIGR02168  357 EAELeeLEAELEELESRLEELEE 379
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 347-604 1.49e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  347 QRRGKTSSFRANLQGAWDDRENARLGLAAATLQSDMEKAGELAARDRAEREASQLkytGEAQKAYERLQTPLDKYTARQK 426
Cdd:COG3096   344 RQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQL---ADYQQALDVQQTRAIQYQQAVQ 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  427 ELNKAlkdGKILQADynTLMASAKKDYESTLKkpsgvkvsageRQEDRAHAAMLALETELRTLEKHSGVNEKISQ----- 501
Cdd:COG3096   421 ALEKA---RALCGLP--DLTPENAEDYLAAFR-----------AKEQQATEEVLELEQKLSVADAARRQFEKAYElvcki 484

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  502 ----QRRDLWEAENQyvVLKEAATKRQLSEQEKSLlaheketleyKRQLAELGDKIEHQKRLNELAQQaarFEQQQSAKQ 577
Cdd:COG3096   485 agevERSQAWQTARE--LLRRYRSQQALAQRLQQL----------RAQLAELEQRLRQQQNAERLLEE---FCQRIGQQL 549

                         250       260
                  ....*....|....*....|....*..
gi 510898460  578 AAISAKARGLTDRQAQRESEEQRLREV 604
Cdd:COG3096   550 DAAEELEELLAELEAQLEELEEQAAEA 576
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
461-619 1.62e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  461 SGVKVSAGERQEDRAHAAMLALETELRTLEkhsgvnEKISQQRRDLWEAENQYVVLKEA----------ATKRQLSEQEK 530
Cdd:COG4913   279 AALRLWFAQRRLELLEAELEELRAELARLE------AELERLEARLDALREELDELEAQirgnggdrleQLEREIERLER 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  531 SLLAHEKETLEYKRQLAELGDKI--------EHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLR 602
Cdd:COG4913   353 ELEERERRRARLEALLAALGLPLpasaeefaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432

                         170
                  ....*....|....*..
gi 510898460  603 EVYGDNPAALAKATSAL 619
Cdd:COG4913   433 RRKSNIPARLLALRDAL 449
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 419-603 3.28e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 3.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 419 DKYTARQKELNKALKDGKILQADYNTLmASAKKDYESTLKKpSGVKVSAGERQEDRAHAAMLALETELRTLEKhsgvneK 498
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAAL-KKEEKALLKQLAA-LERRIAALARRIRALEQELAALEAELAELEK------E 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 499 ISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLL--------------------AHEKETLEYKRQLAELGDKI-EHQK 557
Cdd:COG4942   92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLspedfldavrrlqylkylapARREQAEELRADLAELAALRaELEA 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 510898460 558 RLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLRE 603
Cdd:COG4942  172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 390-603 3.43e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 40.88  E-value: 3.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  390 ARDRAEREASQLK--YTGEAQKAYErLQTPLDKYTARQKELNKALKDgkilqadyNTLMASAKKDYESTLKKpsgvKVSA 467
Cdd:pfam05557  28 ARIELEKKASALKrqLDRESDRNQE-LQKRIRLLEKREAEAEEALRE--------QAELNRLKKKYLEALNK----KLNE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  468 GERQEDRAHAAMLALETELRTLEkhsgvnekisqqrrdlWEAENQyvvlkEAATKRQLSEQEKSLLAHEketlEYKRQLA 547
Cdd:pfam05557  95 KESQLADAREVISCLKNELSELR----------------RQIQRA-----ELELQSTNSELEELQERLD----LLKAKAS 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 510898460  548 ELGDKIE-HQKRLNELAQQAAR-----FEQQQSAKQAAISAKARGLTDRQAQRESEEQRLRE 603
Cdd:pfam05557 150 EAEQLRQnLEKQQSSLAEAEQRikeleFEIQSQEQDSEIVKNSKSELARIPELEKELERLRE 211
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
478-630 4.66e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 4.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 478 AML--ALETELRTLEKHSGVN-----EKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAE-- 548
Cdd:COG4717   45 AMLleRLEKEADELFKPQGRKpelnlKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEkl 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 549 ------LGDKIEHQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKNT 622
Cdd:COG4717  125 lqllplYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204


                 ....*...
gi 510898460 623 WSAEEQLR 630
Cdd:COG4717  205 QQRLAELE 212
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 418-599 5.17e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 40.73  E-value: 5.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   418 LDKYTARQKELNKALKDGKILQADYNTLMaSAKKDYESTLKKPSGVKVS---AGERQEDRAhaamlaLETELRTLEKhsg 494
Cdd:pfam02463  111 INGKNVTKKEVAELLESQGISPEAYNFLV-QGGKIEIIAMMKPERRLEIeeeAAGSRLKRK------KKEALKKLIE--- 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460   495 VNEKISQQRRDLWEAENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAelgdkiEHQKRLNELAQQAARFEQQQS 574
Cdd:pfam02463  181 ETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLK------LNEERIDLLQELLRDEQEEIE 254

                          170       180
                   ....*....|....*....|....*
gi 510898460   575 AKQAAISAKARGLTDRQAQRESEEQ 599
Cdd:pfam02463  255 SSKQEIEKEEEKLAQVLKENKEEEK 279
COG5283 COG5283
Phage-related tail protein [Mobilome: prophages, transposons];
18-469 6.17e-03

Phage-related tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444094 [Multi-domain]  Cd Length: 747  Bit Score: 40.22  E-value: 6.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  18 RFDEQMSRVRRHFSGLdtdaRKTASAVEQGLSRQALAAQKAGISVGQYKAAMRTLPAQFTDIATQLAGGQNPWLILLQQG 97
Cdd:COG5283   39 ALARALERAKQAAARL----QTKYNKLRQSLQRLRQALDQAGIDTRQLSAAQRRLRSSLEQTNRQLERQQQRLARLGARQ 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460  98 GQVK------DSFGGMIPMFRGLAGAITLPMVGVTSLAVAtGALVYAWYQGDSTLSAFN---KTLVLSGNQSGLTADRML 168
Cdd:COG5283  115 DRLKaararlQRLAGAGAAAAAIGAALAASVKPAIDFEDA-MADVAATVDLDKSSEQFKalgKQARELSAQTPQSADDIA 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 169 TLSRAGQAAGLTFNQARESLAALMNAGVRGGEQFDAINQSVARFASASGVEVDKVAEAFGKLTTDPTSGlMAMARQFRNV 248
Cdd:COG5283  194 AGQAALAQAGVSAEDILAFTPTAAKLATAFDTDAEEAAEIAAKILNAFKLPADDVERLGDALNYAGNNG-ATSLADLADA 272

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 249 TAEQIAYVAQLQRSGDEAGALQAAndIATKGFDeqtrrlkenmgtletwADKTGKAFKSMwdaILDIGRPESsadmlaSA 328
Cdd:COG5283  273 LPYVGPVAKALGVSGKEAAALGAA--LADAGIE----------------GEEAGTALRNM---LTRLTSPTK------AA 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 510898460 329 QKAFDEADKKWQwyQSRSQRRGKTSSFRANLQgawDDRENARLGLAAATlqSDMEKAGELAArdraereASQLkYTGEAQ 408
Cdd:COG5283  326 AKALKKLGIDTQ--DSKGNLRGLAKILAKQMQ---KDAQGALAELLKAL--KKLDAAKRAAA-------LKQL-FGEEAV 390

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 510898460 409 KAYERLQTPLDKYTaRQKELNKALKDGKILQADYNTLMASAKKDYESTLKKPSGVKVSAGE 469
Cdd:COG5283  391 SALAPLLQNGDELR-KQLAVAEAAAAQGSMDKEAAKRTDTLAGQLKLLKNALENLGISIGE 450
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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