protein phosphatase 2C domain-containing protein may be a PP2C family serine/threonine-protein phosphatase with a catalytic mechanism similar to that of the PP1, PP2A, PP2B families of protein Ser/Thr phosphatases, but no sequence similarity
Stp1/IreP family PP2C-type Ser/Thr phosphatase; Many Gram-positive bacteria have a protein ...
6-240
2.22e-131
Stp1/IreP family PP2C-type Ser/Thr phosphatase; Many Gram-positive bacteria have a protein kinase/protein phosphatase gene pair that responds to peptidoglycan metabolites and can be instrumental in resistance to beta-lactam antibiotics. Characterized examples of the phosphatase component are Stp1 of Staphylococcus aureus and IreP of Enterococcus faecalis.
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Pssm-ID: 468046 [Multi-domain] Cd Length: 232 Bit Score: 370.22 E-value: 2.22e-131
Stp1/IreP family PP2C-type Ser/Thr phosphatase; Many Gram-positive bacteria have a protein ...
6-240
2.22e-131
Stp1/IreP family PP2C-type Ser/Thr phosphatase; Many Gram-positive bacteria have a protein kinase/protein phosphatase gene pair that responds to peptidoglycan metabolites and can be instrumental in resistance to beta-lactam antibiotics. Characterized examples of the phosphatase component are Stp1 of Staphylococcus aureus and IreP of Enterococcus faecalis.
Pssm-ID: 468046 [Multi-domain] Cd Length: 232 Bit Score: 370.22 E-value: 2.22e-131
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
3-240
3.80e-64
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.
Pssm-ID: 238083 [Multi-domain] Cd Length: 254 Bit Score: 200.25 E-value: 3.80e-64
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
7-239
4.47e-35
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.
Pssm-ID: 214625 [Multi-domain] Cd Length: 252 Bit Score: 125.57 E-value: 4.47e-35
Stp1/IreP family PP2C-type Ser/Thr phosphatase; Many Gram-positive bacteria have a protein ...
6-240
2.22e-131
Stp1/IreP family PP2C-type Ser/Thr phosphatase; Many Gram-positive bacteria have a protein kinase/protein phosphatase gene pair that responds to peptidoglycan metabolites and can be instrumental in resistance to beta-lactam antibiotics. Characterized examples of the phosphatase component are Stp1 of Staphylococcus aureus and IreP of Enterococcus faecalis.
Pssm-ID: 468046 [Multi-domain] Cd Length: 232 Bit Score: 370.22 E-value: 2.22e-131
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
3-240
3.80e-64
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.
Pssm-ID: 238083 [Multi-domain] Cd Length: 254 Bit Score: 200.25 E-value: 3.80e-64
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
7-239
4.47e-35
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.
Pssm-ID: 214625 [Multi-domain] Cd Length: 252 Bit Score: 125.57 E-value: 4.47e-35
Stage II sporulation protein E (SpoIIE); This family contains a number of bacterial stage II ...
31-241
7.41e-08
Stage II sporulation protein E (SpoIIE); This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.
Pssm-ID: 462119 [Multi-domain] Cd Length: 192 Bit Score: 51.11 E-value: 7.41e-08
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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specific hits meet or exceed a domain-specific e-value threshold
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