|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03818 |
PRK03818 |
putative transporter; Validated |
10-552 |
0e+00 |
|
putative transporter; Validated
Pssm-ID: 179654 [Multi-domain] Cd Length: 552 Bit Score: 801.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 10 EHTPLQAVVILSIIIAAGLGLGKIHLFGISLGVTFVFFAGILAGH----LGFSINPDMLNYAESFGLVLFVYELGLQVGP 85
Cdd:PRK03818 1 MSDIALTVSILALVAVVGLWIGNIKIRGVGLGIGGVLFGGIIVGHfvsqFGLTLDSDMLHFIQEFGLILFVYTIGIQVGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 86 GFFSSFRKGGVQLNMLGMGVILTGTVMTVLFSKLGGIPMSDMVGILCGATTNTPALGAAQQTLKQMGEPSS---GAALSC 162
Cdd:PRK03818 81 GFFSSLRKSGLRLNLFAVLIVILGGLVTAILHKLFGIPLPVMLGIFSGAVTNTPALGAGQQILRDLGTPGDlvdQMGMGY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 163 AVTYPLGVVGVILAMLLVRKLFVRPSDIDTHEHE-----DTNQTFIATFKVHNPAIFNKSIKEVALLSYPKFVISRLWRE 237
Cdd:PRK03818 161 AMAYPFGICGILLSMWLIRLIFRINVDKEAQEFEsssgnGHELLQTINIRVENPNLHGKAIKDVPILNGDKFVCSRLKRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 238 GAVSIPTSEKILKENDRLLVITTEKDAPSLTILFGEQEsqdwnkeDIDWNAIDSQLISKHIVISRPEINGKKLGSLRLRN 317
Cdd:PRK03818 241 DTLMVPSPDTIIQLGDLLHLVGQPEDLHKAQLVIGEEV-------DTSLSTRGTDLRSERVVVTNEKVLGKKLRDLHLKN 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 318 SYGINISRVMRSGVQLLATPGLVLQLGDRLTVVGEAKAIENVEKVLGNTAKTLKDPNLAAIFIGIVLGLILGSIPVAIPG 397
Cdd:PRK03818 314 KYGVVISRLNRAGVELVASPDLSLQFGDILNLVGRPEAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFFIPG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 398 ISTPVKLGLAGGPIVVGILIGCFGPRFHLVTYTTRSANLMLRGIGLSLYLACLGLDAGAHFFETVMRPEGAIWIAAGFAI 477
Cdd:PRK03818 394 FPAALKLGLAGGPLIVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLVNGEGLSWIGYGFLI 473
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 511021762 478 TFIPVVIMALVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLP-GDNPAVSYATVYPLSMFSRVIIAQLILMFF 552
Cdd:PRK03818 474 TAVPLLIVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHPtSGAAALSYATVYPLVMFLRIITPQLLAVLF 549
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
15-552 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 577.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 15 QAVVILSIIIAAGLGLGKIHLFGISLGVTFVFFAGILAGHLGFSinPDMLNYAESFGLVLFVYELGLQVGPGFFSSFRKG 94
Cdd:COG2985 10 NPELALFLVIALGYLLGKIKIGGFSLGVAGVLFVGLLIGHFGVT--LHIPHFVKSLGLALFVYAIGLQVGPGFFASLKRD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 95 GVQLNMLGMGVILTGTVMTVLFSKLGGIPMSDMVGILCGATTNTPALGAAQQTLKQMGEP---SSGAALSCAVTYPLGVV 171
Cdd:COG2985 88 GLKLNLLAVVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSkqlSANPAVGYAVAYPFGVI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 172 GVILAMLLVRKLFVR-----PSDIDTHEHEDTNQTFIATFKVHNPAIFNKSIKEVALLSYPKFVISRLWREGAVSIPTSE 246
Cdd:COG2985 168 GIILFVALLPKLFRIdldaeAKKLEAGEGSAYPPLVTRAYRVTNPNLVGKTVAELEALLGTRVVISRIRRGGEIIVPTPD 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 247 KILKENDRLLVITTEKDAPSLTILFGEQESQDwnkedidwNAIDSQLISKHIVISRPEINGKKLGSLRLRNSYGINISRV 326
Cdd:COG2985 248 TVLQEGDIVLVVGTREALEAAEALLGEEVDDS--------ELLDSDLDVRRIVVTNKEVAGKTLGELNLRNRFGVVITRV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 327 MRSGVQLLATPGLVLQLGDRLTVVGEAKAIENVEKVLGNTAKTLKDPNLAAIFIGIVLGLILGSIPVAIPGIStPVKLGL 406
Cdd:COG2985 320 RRGGVELPATPDTVLQLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSIPIPLPGIP-PLSLGL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 407 AGGPIVVGILIGCFGPRFHLVTYTTRSANLMLRGIGLSLYLACLGLDAGAHFFETVMRpEGAIWIAAGFAITFIPVVIMA 486
Cdd:COG2985 399 AGGPLIVGLLLGRLGRTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQE-SGLLLFLLGALVTLVPLLVVL 477
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 511021762 487 LVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLPGDNPAVSYATVYPLSMFSRVIIAQLILMFF 552
Cdd:COG2985 478 LVGRYVLKLNYLILLGALAGAMTSPPALAAANEAAGSDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
382-536 |
3.25e-41 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 145.55 E-value: 3.25e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 382 IVLGLILGSIPVAIPGisTPVKLGLAGGPIVVGILIGCFGPRFHLVTYTTRSANLMLRGIGLSLYLACLGLDAGAHFFET 461
Cdd:TIGR01625 1 LALGLLLGKIPIGLPG--FSIKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSS 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 511021762 462 VMRPEGAIWIAAGFAITFIPVVIMALVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLP-GDNPAVSYATVYPL 536
Cdd:TIGR01625 79 LKDGGGLLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRtSDLPALGYATVYPL 154
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
377-550 |
1.19e-38 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 139.24 E-value: 1.19e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 377 AIFIGIVLGLILGSIPvaipgISTPVKLGLAGGPIVVGILIGCFGPRFHlvTYTTRSANLMLRGIGLSLYLACLGLDAGA 456
Cdd:pfam06826 1 ALFLGIALGLLLGRIK-----ISGGFSLGVAGGVLIVGLLLGHFGSTGP--TFMPISALSFLRELGLALFLAAVGLSAGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 457 HFFETVMRPeGAIWIAAGFAITFIPVVIMALVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLPG-DNPAVSYATVYP 535
Cdd:pfam06826 74 GFFSSLKKD-GLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDALAGsDIPALGYAVTYP 152
|
170
....*....|....*
gi 511021762 536 LSMFSRVIIAQLILM 550
Cdd:pfam06826 153 FGVVGLILAGQVLAK 167
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03818 |
PRK03818 |
putative transporter; Validated |
10-552 |
0e+00 |
|
putative transporter; Validated
Pssm-ID: 179654 [Multi-domain] Cd Length: 552 Bit Score: 801.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 10 EHTPLQAVVILSIIIAAGLGLGKIHLFGISLGVTFVFFAGILAGH----LGFSINPDMLNYAESFGLVLFVYELGLQVGP 85
Cdd:PRK03818 1 MSDIALTVSILALVAVVGLWIGNIKIRGVGLGIGGVLFGGIIVGHfvsqFGLTLDSDMLHFIQEFGLILFVYTIGIQVGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 86 GFFSSFRKGGVQLNMLGMGVILTGTVMTVLFSKLGGIPMSDMVGILCGATTNTPALGAAQQTLKQMGEPSS---GAALSC 162
Cdd:PRK03818 81 GFFSSLRKSGLRLNLFAVLIVILGGLVTAILHKLFGIPLPVMLGIFSGAVTNTPALGAGQQILRDLGTPGDlvdQMGMGY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 163 AVTYPLGVVGVILAMLLVRKLFVRPSDIDTHEHE-----DTNQTFIATFKVHNPAIFNKSIKEVALLSYPKFVISRLWRE 237
Cdd:PRK03818 161 AMAYPFGICGILLSMWLIRLIFRINVDKEAQEFEsssgnGHELLQTINIRVENPNLHGKAIKDVPILNGDKFVCSRLKRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 238 GAVSIPTSEKILKENDRLLVITTEKDAPSLTILFGEQEsqdwnkeDIDWNAIDSQLISKHIVISRPEINGKKLGSLRLRN 317
Cdd:PRK03818 241 DTLMVPSPDTIIQLGDLLHLVGQPEDLHKAQLVIGEEV-------DTSLSTRGTDLRSERVVVTNEKVLGKKLRDLHLKN 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 318 SYGINISRVMRSGVQLLATPGLVLQLGDRLTVVGEAKAIENVEKVLGNTAKTLKDPNLAAIFIGIVLGLILGSIPVAIPG 397
Cdd:PRK03818 314 KYGVVISRLNRAGVELVASPDLSLQFGDILNLVGRPEAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFFIPG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 398 ISTPVKLGLAGGPIVVGILIGCFGPRFHLVTYTTRSANLMLRGIGLSLYLACLGLDAGAHFFETVMRPEGAIWIAAGFAI 477
Cdd:PRK03818 394 FPAALKLGLAGGPLIVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLVNGEGLSWIGYGFLI 473
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 511021762 478 TFIPVVIMALVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLP-GDNPAVSYATVYPLSMFSRVIIAQLILMFF 552
Cdd:PRK03818 474 TAVPLLIVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHPtSGAAALSYATVYPLVMFLRIITPQLLAVLF 549
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
15-552 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 577.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 15 QAVVILSIIIAAGLGLGKIHLFGISLGVTFVFFAGILAGHLGFSinPDMLNYAESFGLVLFVYELGLQVGPGFFSSFRKG 94
Cdd:COG2985 10 NPELALFLVIALGYLLGKIKIGGFSLGVAGVLFVGLLIGHFGVT--LHIPHFVKSLGLALFVYAIGLQVGPGFFASLKRD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 95 GVQLNMLGMGVILTGTVMTVLFSKLGGIPMSDMVGILCGATTNTPALGAAQQTLKQMGEP---SSGAALSCAVTYPLGVV 171
Cdd:COG2985 88 GLKLNLLAVVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSkqlSANPAVGYAVAYPFGVI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 172 GVILAMLLVRKLFVR-----PSDIDTHEHEDTNQTFIATFKVHNPAIFNKSIKEVALLSYPKFVISRLWREGAVSIPTSE 246
Cdd:COG2985 168 GIILFVALLPKLFRIdldaeAKKLEAGEGSAYPPLVTRAYRVTNPNLVGKTVAELEALLGTRVVISRIRRGGEIIVPTPD 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 247 KILKENDRLLVITTEKDAPSLTILFGEQESQDwnkedidwNAIDSQLISKHIVISRPEINGKKLGSLRLRNSYGINISRV 326
Cdd:COG2985 248 TVLQEGDIVLVVGTREALEAAEALLGEEVDDS--------ELLDSDLDVRRIVVTNKEVAGKTLGELNLRNRFGVVITRV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 327 MRSGVQLLATPGLVLQLGDRLTVVGEAKAIENVEKVLGNTAKTLKDPNLAAIFIGIVLGLILGSIPVAIPGIStPVKLGL 406
Cdd:COG2985 320 RRGGVELPATPDTVLQLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSIPIPLPGIP-PLSLGL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 407 AGGPIVVGILIGCFGPRFHLVTYTTRSANLMLRGIGLSLYLACLGLDAGAHFFETVMRpEGAIWIAAGFAITFIPVVIMA 486
Cdd:COG2985 399 AGGPLIVGLLLGRLGRTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQE-SGLLLFLLGALVTLVPLLVVL 477
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 511021762 487 LVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLPGDNPAVSYATVYPLSMFSRVIIAQLILMFF 552
Cdd:COG2985 478 LVGRYVLKLNYLILLGALAGAMTSPPALAAANEAAGSDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| PRK04972 |
PRK04972 |
putative transporter; Provisional |
17-552 |
1.13e-43 |
|
putative transporter; Provisional
Pssm-ID: 179905 [Multi-domain] Cd Length: 558 Bit Score: 163.36 E-value: 1.13e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 17 VVILSIIIAAGLGLGKIHLFGISLGVTF-VFFAGILAGHLGFSINPDMLNyaesFGLVLFVYELGLQVGPGFFSSFRKGG 95
Cdd:PRK04972 14 ILLLFVVLALGLCLGKLRLGSIQLGNSIgVLVVSLLLGQQHFSINTDALN----LGFMLFIFCVGVEAGPNFFSIFFRDG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 96 VQLNMLGMGVILTGTVMTVLFSKLGGIPMSDMVGILCGATTNTPALGAAQQTLK-------QMGEPSSGAALSCAVTYPL 168
Cdd:PRK04972 90 KNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRhsgaesrQLSLALDNLSLGYALTYLI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 169 GVVGVILAMLLVRKL-----------FVRPSDIDTHEHEDTNQTFIATFKVhNPAIFN----KSIKEVALLSYPKFVISR 233
Cdd:PRK04972 170 GLVSLIVGARYLPKLqhqdlqtsaqqIARERGLDTDAQRKVYLPVIRAYRV-GPELVAwtdgKNLRELGIYRQTGCYIER 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 234 LWREGAVSIPTSEKILKENDRLLVITTEKDAPSLTILFGEqesqdwNKEDIDWNAIDSQLISKHIVISRPEINGKKLGSL 313
Cdd:PRK04972 249 IRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRN------GKEVFDRDLLDMRIVTEEIVVKNHNAVGKRLSQL 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 314 RLrNSYGINISRVMRSGVQLLATPGLVLQLGDRLTVVGEAKAIENVEKVLGNTAKTLKDPNLAAIFIGIVLGLILGSIPV 393
Cdd:PRK04972 323 KL-TDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITF 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 394 AIPGIStpVKLGLAGGPIVVGILIGCFGPRFHLVTYTTRSANLMLRGIGLSLYLACLGLDAGAHFFETvMRPEGAIWIAA 473
Cdd:PRK04972 402 QFSNFS--FGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGINNG-LGAVGGQMLIA 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 474 GFAITFIPVVIMALV---ALRMSR-LDFGTTCGMLCGSMANPMALNYANDTLpgdnPAVSYATVYPLSMFSRVIIAQLIL 549
Cdd:PRK04972 479 GLIVSLVPVVICFLFgayVLRMNRaLLFGAIMGARTCAPAMEIISDTARSNI----PALGYAGTYAIANVLLTLAGTLIV 554
|
...
gi 511021762 550 MFF 552
Cdd:PRK04972 555 IVW 557
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
382-536 |
3.25e-41 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 145.55 E-value: 3.25e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 382 IVLGLILGSIPVAIPGisTPVKLGLAGGPIVVGILIGCFGPRFHLVTYTTRSANLMLRGIGLSLYLACLGLDAGAHFFET 461
Cdd:TIGR01625 1 LALGLLLGKIPIGLPG--FSIKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSS 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 511021762 462 VMRPEGAIWIAAGFAITFIPVVIMALVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLP-GDNPAVSYATVYPL 536
Cdd:TIGR01625 79 LKDGGGLLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRtSDLPALGYATVYPL 154
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
377-550 |
1.19e-38 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 139.24 E-value: 1.19e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 377 AIFIGIVLGLILGSIPvaipgISTPVKLGLAGGPIVVGILIGCFGPRFHlvTYTTRSANLMLRGIGLSLYLACLGLDAGA 456
Cdd:pfam06826 1 ALFLGIALGLLLGRIK-----ISGGFSLGVAGGVLIVGLLLGHFGSTGP--TFMPISALSFLRELGLALFLAAVGLSAGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 457 HFFETVMRPeGAIWIAAGFAITFIPVVIMALVALRMSRLDFGTTCGMLCGSMANPMALNYANDTLPG-DNPAVSYATVYP 535
Cdd:pfam06826 74 GFFSSLKKD-GLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDALAGsDIPALGYAVTYP 152
|
170
....*....|....*
gi 511021762 536 LSMFSRVIIAQLILM 550
Cdd:pfam06826 153 FGVVGLILAGQVLAK 167
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
20-182 |
8.42e-36 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 131.54 E-value: 8.42e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 20 LSIIIAAGLGLGKIHL-FGISLGVT-FVFFAGILAGHLGFS----INPDMLNYAESFGLVLFVYELGLQVGPGFFSSFRK 93
Cdd:pfam06826 2 LFLGIALGLLLGRIKIsGGFSLGVAgGVLIVGLLLGHFGSTgptfMPISALSFLRELGLALFLAAVGLSAGPGFFSSLKK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 94 GGVQLNMLGMGVILTGTVMTVLFSK-LGGIPMSDMVGILCGATTNTPALGAAQQTLKQMGEPssgaALSCAVTYPLGVVG 172
Cdd:pfam06826 82 DGLLLIGLALLVTVVPLLLALVLGKyVLKLDPGLLAGLLAGALTSTPALGAANDALAGSDIP----ALGYAVTYPFGVVG 157
|
170
....*....|
gi 511021762 173 VILAMLLVRK 182
Cdd:pfam06826 158 LILAGQVLAK 167
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
24-168 |
1.46e-28 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 110.88 E-value: 1.46e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 24 IAAGLGLGKIHLFG----ISLG-VTFVFFAGILAGHLGFS------INPDMLNYAESFGLVLFVYELGLQVGPGFFSSFR 92
Cdd:TIGR01625 1 LALGLLLGKIPIGLpgfsIKLGnAGGVLFVGLLLGHFGATgpltwyIPFSANLFIREFGLMLFLYGVGLSAGPGFFSSLK 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 511021762 93 KGGVQLNMLGMGVILTGTVMTVLF--SKLGGIPMSDMVGILCGATTNTPALGAAQQTLKQMGEPssgaALSCAVTYPL 168
Cdd:TIGR01625 81 DGGGLLRINGGALITVVPTLLVAValIKLLRINYALTAGMLAGATTNTPALDAANDTLRTSDLP----ALGYATVYPL 154
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
307-363 |
1.28e-09 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 54.54 E-value: 1.28e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 511021762 307 GKKLGSLRLRNSYGINISRVMRSGVQLLATPGLVLQLGDRLTVVGEAKAIENVEKVL 363
Cdd:pfam02080 14 GKTLKELNLPERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| KhtT |
COG0490 |
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ... |
307-363 |
9.79e-06 |
|
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440256 [Multi-domain] Cd Length: 140 Bit Score: 45.30 E-value: 9.79e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 511021762 307 GKKLGSLRLRNSYGINISRVMRSGvQLLATPG--LVLQLGDRLTVVGEAKAIENVEKVL 363
Cdd:COG0490 83 GKTLGELNLRQRTGVTVVAIRRGG-EVILSPGpdTVLEAGDTLVVVGTREQLERLEELL 140
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
210-271 |
1.13e-04 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 40.67 E-value: 1.13e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 511021762 210 NPAIFNKSIKEVALLSYPKFVISRLWREGAVSIPTSEKILKENDRLLVITTEKDAPSLTILF 271
Cdd:pfam02080 9 NSPLVGKTLKELNLPERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
170-256 |
2.19e-03 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 40.44 E-value: 2.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 511021762 170 VVGVILAMLLVRKLFVRPSDIDTHEHEdtnqtfIATFKVH-NPAIFNKSIKEVALLSYPKFVISRLWREGAVSIPTSEKI 248
Cdd:COG0569 215 LAARRIARLLLRPGVLDVLELADGDAE------IVEVTVPeGSPLVGKTLKELDLRERYGVTVVAIKRGGEVIIPSGDTV 288
|
....*...
gi 511021762 249 LKENDRLL 256
Cdd:COG0569 289 LEAGDELI 296
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
298-347 |
4.49e-03 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 39.28 E-value: 4.49e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 511021762 298 IVISRPEINGKKLGSLRLRNSYGINISRVMRSGVQLLATPGLVLQLGDRL 347
Cdd:COG0569 246 TVPEGSPLVGKTLKELDLRERYGVTVVAIKRGGEVIIPSGDTVLEAGDEL 295
|
|
| |
