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Conserved domains on  [gi|512474571|ref|WP_016425447|]
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MULTISPECIES: peptidylprolyl isomerase [Staphylococcus]

Protein Classification

peptidylprolyl isomerase( domain architecture ID 1000880)

peptidylprolyl isomerase plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins, and it functions as a peptidyl-prolyl cis-trans isomerase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0006457
PubMed:  10228556

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
prsA super family cl35263
peptidylprolyl isomerase; Provisional
 1-298 6.52e-24

peptidylprolyl isomerase; Provisional


The actual alignment was detected with superfamily member PRK04405:

Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 99.09  E-value: 6.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571   1 MKKGIQK--LVIPVTASALLLGACGndaptSKGETLISSKAGDVKVQDVLKEIGNEQIASDSF-KVLLNKILEEKYGKKV 77
Cdd:PRK04405   1 MKKKMKKwaLAAASAGLALSLAGCS-----SNQATVATYSGGKITQSQYYKEMKQSSAGKTVLaNMIIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  78 DDKQIDKETDEEIEKYGgkDQFKNLLKQQGMSLDEYKKQRKMIAYQKELLNDKVKISDKEIKDNTKK------ASHILIk 151
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSyqpkvtVQHILV- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 152 vkqdkddkeglSDKDAKKKIEEIKkeidKNPKSFDDLAKKESMDSS-KDKNGSLGYVVKGQTV--KPFEKALFKLKDGEI 228
Cdd:PRK04405 153 -----------SKKSTAETVIKKL----KDGKDFAKLAKKYSTDTAtKNKGGKLSAFDSTDTTldSTFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512474571 229 -SDIVKTDYGYHIIRADKPTDFNK--EKSKLKEKLIQNKLQKDPEILTNAYKDLLKEYDVDYKDRDIKKAIED 298
Cdd:PRK04405 218 tTTPVKTTYGYEVIKMIKHPAKGTfsDHKKALTKQIYAKWASDSSVMQRVISKVLKKANVSIKDKDLKDALSS 290
 
Name Accession Description Interval E-value
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-298 6.52e-24

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 99.09  E-value: 6.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571   1 MKKGIQK--LVIPVTASALLLGACGndaptSKGETLISSKAGDVKVQDVLKEIGNEQIASDSF-KVLLNKILEEKYGKKV 77
Cdd:PRK04405   1 MKKKMKKwaLAAASAGLALSLAGCS-----SNQATVATYSGGKITQSQYYKEMKQSSAGKTVLaNMIIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  78 DDKQIDKETDEEIEKYGgkDQFKNLLKQQGMSLDEYKKQRKMIAYQKELLNDKVKISDKEIKDNTKK------ASHILIk 151
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSyqpkvtVQHILV- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 152 vkqdkddkeglSDKDAKKKIEEIKkeidKNPKSFDDLAKKESMDSS-KDKNGSLGYVVKGQTV--KPFEKALFKLKDGEI 228
Cdd:PRK04405 153 -----------SKKSTAETVIKKL----KDGKDFAKLAKKYSTDTAtKNKGGKLSAFDSTDTTldSTFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512474571 229 -SDIVKTDYGYHIIRADKPTDFNK--EKSKLKEKLIQNKLQKDPEILTNAYKDLLKEYDVDYKDRDIKKAIED 298
Cdd:PRK04405 218 tTTPVKTTYGYEVIKMIKHPAKGTfsDHKKALTKQIYAKWASDSSVMQRVISKVLKKANVSIKDKDLKDALSS 290
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 144-285 6.36e-23

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 92.33  E-value: 6.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 144 KASHILIKVKQDKDDKEglSDKDAKKKIEEIkkeidKNPKSFDDLAKKESMD-SSKDKNGSLGYVVKGQTVKPFEKALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK--AEAKAEELLAQL-----KAGADFAELAKEYSQDpGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512474571 223 LKDGEISDIVKTDYGYHIIRADKPTDFNKEKSKLKEKLIQNKLQKdpEILTNAYKDLLKEYDV 285
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQ--QALEAWLEELRKKAKI 143
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-245 7.68e-20

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 82.73  E-value: 7.68e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  147 HILIKVKqdkdDKEGLSDKDAKKKIEEIKKEIDKNPKSFDDLAKKESMD-SSKDKNGSLGYVVKGQTVKPFEKALFKLKD 225
Cdd:pfam00639   1 HILIKTP----EASERDRAEAKAKAEEILEQLKSGEDSFAELARKYSDDcPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 512474571  226 GEISDIVKTDYGYHIIRADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
 
Name Accession Description Interval E-value
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-298 6.52e-24

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 99.09  E-value: 6.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571   1 MKKGIQK--LVIPVTASALLLGACGndaptSKGETLISSKAGDVKVQDVLKEIGNEQIASDSF-KVLLNKILEEKYGKKV 77
Cdd:PRK04405   1 MKKKMKKwaLAAASAGLALSLAGCS-----SNQATVATYSGGKITQSQYYKEMKQSSAGKTVLaNMIIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  78 DDKQIDKETDEEIEKYGgkDQFKNLLKQQGMSLDEYKKQRKMIAYQKELLNDKVKISDKEIKDNTKK------ASHILIk 151
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSyqpkvtVQHILV- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 152 vkqdkddkeglSDKDAKKKIEEIKkeidKNPKSFDDLAKKESMDSS-KDKNGSLGYVVKGQTV--KPFEKALFKLKDGEI 228
Cdd:PRK04405 153 -----------SKKSTAETVIKKL----KDGKDFAKLAKKYSTDTAtKNKGGKLSAFDSTDTTldSTFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512474571 229 -SDIVKTDYGYHIIRADKPTDFNK--EKSKLKEKLIQNKLQKDPEILTNAYKDLLKEYDVDYKDRDIKKAIED 298
Cdd:PRK04405 218 tTTPVKTTYGYEVIKMIKHPAKGTfsDHKKALTKQIYAKWASDSSVMQRVISKVLKKANVSIKDKDLKDALSS 290
prsA PRK03095
peptidylprolyl isomerase PrsA;
1-298 7.21e-24

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 98.91  E-value: 7.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571   1 MKKGIQKLVipvTASALLLGACGndapTSKGETLISSKAGDVKvqdvlKEIGNEQIASDSFKVLLNKILEEKY---GKKV 77
Cdd:PRK03095   1 MKKAMLALA---ATSVIALSACG----TSSSDKIVTSKAGDIT-----KDEFYEQMKTQAGKQVLNNMVMEKVlikNYKV 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  78 DDKQIDKETDEEIEKYGgkDQFKNLLKQQGMSLDEYKKQ-RKMIAYQKELlndKVKISDKEIKDNTK---KASHILIKVK 153
Cdd:PRK03095  69 EDKEVDKKYDEMKKQYG--DQFDTLLKQQGIKEETLKTGvRAQLAQEKAI---EKTITDKELKDNYKpeiKASHILVKDE 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 154 QD-KDDKEGLSDKdakkkieeikkeidknpKSFDDLAKKESMDS-SKDKNGSLGYVVKGQTVKPFEKALFKLKDGEISDI 231
Cdd:PRK03095 144 ATaKKVKEELGQG-----------------KSFEELAKQYSEDTgSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEP 206

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 512474571 232 VKTDYGYHIIRA----DKPTDFNKEKSKLKEKLIQNKLQkDPEILTNAYKDLLKEYDVDYKDRDIKKAIED 298
Cdd:PRK03095 207 VKSQFGYHIIKVtdikEPEKSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEE 276
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 144-285 6.36e-23

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 92.33  E-value: 6.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 144 KASHILIKVKQDKDDKEglSDKDAKKKIEEIkkeidKNPKSFDDLAKKESMD-SSKDKNGSLGYVVKGQTVKPFEKALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK--AEAKAEELLAQL-----KAGADFAELAKEYSQDpGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512474571 223 LKDGEISDIVKTDYGYHIIRADKPTDFNKEKSKLKEKLIQNKLQKdpEILTNAYKDLLKEYDV 285
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQ--QALEAWLEELRKKAKI 143
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 16-297 8.70e-21

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 90.42  E-value: 8.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  16 ALLLGACGNDaptskgETLISSKAGDVKVQDVLKEIGNEQIASDSFKVLLNKILEEKYgkKVDDKQIDKETDEEIEKYGg 95
Cdd:PRK02998  16 VLALSACGSS------DNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKY--KVSDEEAKKQVEEAKDKMG- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  96 kDQFKNLLKQQGM-SLDEYKKQRKM-IAYQKELlndKVKISDKEIKDNTK---KASHILIK-VKQDKDDKEGLSdkdakk 169
Cdd:PRK02998  87 -DNFKSTLEQVGLkNEDELKEKMKPeIAFEKAI---KATVTEKDVKDNYKpemKVSHILVKdEKTAKEVKEKVN------ 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 170 kieeikkeidkNPKSFDDLAKKESMDS-SKDKNGSLGYVVKGQTVKPFEKALFKLKDGEISDIVKTDYGYHIIRADKPTD 248
Cdd:PRK02998 157 -----------NGEDFAALAKQYSEDTgSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKE 225

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 512474571 249 ---FNKEKSKLKEKLIQNKLQK-DPEILTNAYKDLLKEYDVDYKDRDIKKAIE 297
Cdd:PRK02998 226 lkpFDEVKDSIRKDLEQQRLQDtTGKWKQQVVNDLLKDADIKVNDKEFKDTFK 278
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-245 7.68e-20

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 82.73  E-value: 7.68e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  147 HILIKVKqdkdDKEGLSDKDAKKKIEEIKKEIDKNPKSFDDLAKKESMD-SSKDKNGSLGYVVKGQTVKPFEKALFKLKD 225
Cdd:pfam00639   1 HILIKTP----EASERDRAEAKAKAEEILEQLKSGEDSFAELARKYSDDcPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 512474571  226 GEISDIVKTDYGYHIIRADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 131-247 1.41e-19

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 82.80  E-value: 1.41e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  131 VKISDKEIKDNTKKASHILIKVKQDKDDKEGLSDKDAKKKIEEIkkeidKNPKSFDDLAKKESMD-SSKDKNGSLGYVVK 209
Cdd:pfam13616   4 SKLVDKKSAPDSVKASHILISYSQAVSRTEEEAKAKADSLLAAL-----KNGADFAALAKTYSDDpASKNNGGDLGWFTK 78

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 512474571  210 GQTVKPFEKALFKLKDGEISDIVKTDYGYHIIRADKPT 247
Cdd:pfam13616  79 GQMVKEFEDAVFSLKVGEISGVVKTQFGFHIIKVTDKK 116
prsA PRK03002
peptidylprolyl isomerase PrsA;
3-293 5.81e-19

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 85.37  E-value: 5.81e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571   3 KGIQKLVIPVTASALLLGACGNDAPTSkgeTLISSKAGDVKVQDVLKEIGNEQIASDSFKVLLNKILEEKYgkKVDDKQI 82
Cdd:PRK03002   2 RGKHIFIITALISILMLSACGQKNSSA---TVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKY--KVSDDDV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  83 DKETDEEIEKYGgkDQFKNLLKQQGMS-LDEYKKQRKMIAYQKELLndKVKISDKEIKDNTK---KASHILIKVKQDKDD 158
Cdd:PRK03002  77 DKEVQKAKSQYG--DQFKNVLKNNGLKdEADFKNQIKFKLAMNEAI--KKSVTEKDVKDHYKpeiKASHILVSDENEAKE 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 159 KEGLSDKDAkkkieeikkeidknpkSFDDLAKKESMD-SSKDKNGSLGYVVKGQTVKPFEKALFKLKDGEISDIVKTDYG 237
Cdd:PRK03002 153 IKKKLDAGA----------------SFEELAKQESQDlLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNG 216

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 512474571 238 YHIIRADKPTDFN--KEKSKLKEKLIQNKLQKDPEILTNAYKDLLKEYDVDYKDRDIK 293
Cdd:PRK03002 217 YHIIKLTDKKDLKpyDEVKDSIRKNLEEERTADPIFGKKLLQSELKKANIKINDSELE 274
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 144-241 4.15e-18

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 78.53  E-value: 4.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 144 KASHILIK-------VKQDKDDKEGLSDKDAKKKIEEIKKEIDKNPKSFDDLAKKESMDSSKDKNGSLGYVVKGQTVKPF 216
Cdd:PTZ00356   7 RAAHLLIKhtgsrnpVSRRTGKPVTRSKEEAIKELAKWREQIVSGEKTFEEIARQRSDCGSAAKGGDLGFFGRGQMQKPF 86

                         90       100
                 ....*....|....*....|....*
gi 512474571 217 EKALFKLKDGEISDIVKTDYGYHII 241
Cdd:PTZ00356  87 EDAAFALKVGEISDIVHTDSGVHII 111
prsA PRK00059
peptidylprolyl isomerase; Provisional
 62-292 9.30e-15

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 73.98  E-value: 9.30e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  62 KVLLNKILEEKYgkKVDDKQIDKETDEEI-----EKYGGKDQFKNLLKQQGMSLDEYKKQRKMIAYQKELLND---KVKI 133
Cdd:PRK00059  97 KVLLQKAKELKL--IPSEEELNKEVDKKIneikkQFNNDEEQFEEALKATGFTEETFKEYLKNQIIIEKVINEvvkDVKV 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 134 SDKEIKD-------------NTKKASHILIKVKQD-KDDKEGLSDKdakkkieeikkeidknpKSFDDLAKKESMD-SSK 198
Cdd:PRK00059 175 TDKDAQKyynenkskftekpNTMHLAHILVKTEDEaKKVKKRLDKG-----------------EDFAKVAKEVSQDpGSK 237

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 199 DKNGSLGYV--VKGQTVKPFEKALFKLKDGEISDIVKTDYGYHIIRADKPTDFNKEKSKLKEKLIQNKL--QKDPEILTN 274
Cdd:PRK00059 238 DKGGDLGDVpySDSGYDKEFMDGAKALKEGEISAPVKTQFGYHIIKAIKKKEYPVKPFDSVKEDIKKQLlqEKQSEVFKK 317

                        250
                 ....*....|....*...
gi 512474571 275 AYKDLLKEYDVDYKDRDI 292
Cdd:PRK00059 318 KIEEWKKALKVKKYEKNL 335
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 1-290 1.02e-10

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 61.64  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571   1 MKKGIQKLVIPVT-ASALLLGACGNdapTSKGETLISSKAGDVKVQDVLKEIGNEQIASDS-FKVLLNKILEEKYGKKVD 78
Cdd:PRK12450   1 MKQMNKLITGVVTlATVVTLSACQS---SHNNTKLVSMKGDTITVSDFYNETKNTELAQKAmLSLVISRVFETQYANKVS 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  79 DKQIDKETDEEIEKYGGkdQFKNLLKQQGMSLDEYKKQ---RKMIAYQKELLNDKVKISDKEIKDN----TKKASHILIK 151
Cdd:PRK12450  78 DKEVEKAYKQTADQYGT--SFKTVLAQSGLTPETYKKQirlTKLVEYAVKEQAKNETISKKDYRQAydayTPTMTAEIMQ 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 152 VKQDKDDKEGLSDKDAKKKieeikkeidknpkSFDDLAKKESMDSSKDKNGSLGyvvKGQTVKPFE--KALFKLKDGEIS 229
Cdd:PRK12450 156 FEKEEDAKAALEAVKAEGA-------------DFAAIAKEKTIAADKKTTYTFD---SGETTLPAEvvRAASGLKEGNRS 219

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 512474571 230 DIVK------TDYGYHII----RADKPTDFNKEKSKLKEKLIQNKLQkDPEILTNAYKDLLKEYDVDYKDR 290
Cdd:PRK12450 220 EIITaldpatSKRTYHIIkvtkKATKKADWKAYQKRLKDIIVTGKLK-DPDFQNKVIAKALDKANVKIKDK 289
prsA PRK01326
foldase protein PrsA; Reviewed
 14-234 6.56e-10

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 59.44  E-value: 6.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  14 ASALLLGACGNdapTSKGETLISSKAGDVKVQDVLKEIGNEQIASDS-FKVLLNKILEEKYGKKVDDKQIDKETDEEIEK 92
Cdd:PRK01326  13 LSVATLAACSK---TNENTKVISMKGDTITVSDFYNQVKNNPSAQQAmLNLTISRVFEKQYGDKVSDKEVEKAYAKTAKQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  93 YGgkDQFKNLLKQQGMSLDEYKKQ---RKMIAY------QKELLNDKVKisdKEIKDNTKKASHILIKVKQDKDDKEGLS 163
Cdd:PRK01326  90 YG--ASFSRALAQAGLTPETYKAQirtSKLVEYavkeaaKKELTDEAYK---KAYEEYTPEVTAQIIRLDNEDKAKSVLE 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512474571 164 DKDAKKKieeikkeidknpkSFDDLAKKESmdSSKDKNGSLGYVVKGQTV-KPFEKALFKLKDGEISDIVKT 234
Cdd:PRK01326 165 EAKAEGA-------------DFAQIAKENT--TTKEKKGEYKFDSGSTNVpEQVKKAAFALDEDGVSDVISV 221
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 180-242 1.15e-06

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 46.17  E-value: 1.15e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 512474571 180 KNPKSFDDLAKKESMDSSKDKNGSLGYVVKGQTVKPFEKALFKLKDGEISDIVKTDYGYHIIR 242
Cdd:PRK15441  26 KNGADFGKLAKKHSICPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIK 88
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 86-244 4.50e-04

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 41.92  E-value: 4.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  86 TDEEIEKYggKDQFKNLLkqqgMSLDEYKkqrkmIAYQK---ELLNDKVKISDKEIKD------------NTKKAShiLI 150
Cdd:PRK10788 210 TDEEIKSY--YDQNKNNF----MAPEQFK-----VSYIKldaATMQQKITVSDADIQAyydqhqdqftqpERKRYS--II 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571 151 KVKQDKDDKEGLsdkDAKkkieeikkeidKNPKSFDDLAKKESMDS-SKDKNGSLGYVVKGQTVKPFEKALFKLKdGEIS 229
Cdd:PRK10788 277 QTKTEAEAKAVL---DEL-----------KKGADFATLAKEKSTDIiSARNGGDLGWLEPATTPDELKNAGLKEK-GQLS 341

                        170
                 ....*....|....*
gi 512474571 230 DIVKTDYGYHIIRAD 244
Cdd:PRK10788 342 GVIKSSVGFLIVRLD 356
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 184-241 8.05e-04

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 40.88  E-value: 8.05e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 512474571 184 SFDDLAKKESMD-SSKDKNGSLGYVVKGQTVKPFEKALFKLKDGEISDIVKTDYGYHII 241
Cdd:PRK10770 302 TFAAAAKEFSQDpGSANQGGDLGWATPDIFDPAFRDALMRLNKGQISAPVHSSFGWHLI 360
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
165-245 1.11e-03

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 38.19  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512474571  165 KDAKKKIEEIKKEIDKNPKSFDDLAKKESmdsskDKNGSLGYVVKGQTV-KPFEKALFKLKDGEISDIVKTDYGYHIIRA 243
Cdd:pfam13145  31 KDQVAADAALALLKAGALEDFAALAKGEG-----IKAATLDIVESAELLpEELAKAAFALKPGEVSGPIKTGNGYYVVRV 105


                  ..
gi 512474571  244 DK 245
Cdd:pfam13145 106 TE 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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