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Conserved domains on  [gi|512630190|ref|WP_016460325|]
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MULTISPECIES: 50S ribosomal protein L24 [Actinomycetes]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-113 1.09e-34

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 116.32  E-value: 1.09e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190   1 MAAKIRKNDLVEVVRGRtsdekalakrnarraeegleplkpgDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSA 80
Cdd:COG0198    1 MKMKIKKGDTVIVIAGK-------------------------DKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQ 55

                         90       100       110
                 ....*....|....*....|....*....|...
gi 512630190  81 GGIETIEAPIALSKVALVDPETKKRVRVGFRED 113
Cdd:COG0198   56 GGIIEKEAPIHISNVMLVDPKTGKPTRVGFKVL 88
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-113 1.09e-34

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 116.32  E-value: 1.09e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190   1 MAAKIRKNDLVEVVRGRtsdekalakrnarraeegleplkpgDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSA 80
Cdd:COG0198    1 MKMKIKKGDTVIVIAGK-------------------------DKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQ 55

                         90       100       110
                 ....*....|....*....|....*....|...
gi 512630190  81 GGIETIEAPIALSKVALVDPETKKRVRVGFRED 113
Cdd:COG0198   56 GGIIEKEAPIHISNVMLVDPKTGKPTRVGFKVL 88
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 3-111 7.86e-22

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 83.47  E-value: 7.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190    3 AKIRKNDLVEVVRGrtsdekalakrnarraeegleplkpGDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSAGG 82
Cdd:TIGR01079   1 MKIKKGDTVKVISG-------------------------KDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRQGG 55

                          90       100
                  ....*....|....*....|....*....
gi 512630190   83 IETIEAPIALSKVALVDPETKKRVRVGFR 111
Cdd:TIGR01079  56 IIEKEAPIHISNVMLFDPKTGKATRVGYR 84
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 8-97 1.11e-18

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 74.47  E-value: 1.11e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190   8 NDLVEVVRGRtsdekalakrnarraeegleplkpgDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSAGGIETIE 87
Cdd:cd06089    1 GDEVQVIRGK-------------------------DKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPQGGIIEVE 55

                         90
                 ....*....|
gi 512630190  88 APIALSKVAL 97
Cdd:cd06089   56 APIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 65-113 3.93e-16

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 67.47  E-value: 3.93e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 512630190   65 INLKTRHVRQGQQGSAGGIETIEAPIALSKVALVDPETKKRVRVGFRED 113
Cdd:pfam17136   1 VNMVKKHVKPSQQNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVGFKED 49
rpl24 CHL00141
ribosomal protein L24; Validated
 43-104 8.79e-13

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 59.66  E-value: 8.79e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512630190  43 DKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSAGGIETIEAPIALSKVALVDPETKK 104
Cdd:CHL00141  22 DKGKIGEVLKIIKKSNKVIVKGINIKFKHIKPNKENEVGEIKQFEAPIHSSNVMLYNEESNI 83
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-113 1.09e-34

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 116.32  E-value: 1.09e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190   1 MAAKIRKNDLVEVVRGRtsdekalakrnarraeegleplkpgDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSA 80
Cdd:COG0198    1 MKMKIKKGDTVIVIAGK-------------------------DKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQ 55

                         90       100       110
                 ....*....|....*....|....*....|...
gi 512630190  81 GGIETIEAPIALSKVALVDPETKKRVRVGFRED 113
Cdd:COG0198   56 GGIIEKEAPIHISNVMLVDPKTGKPTRVGFKVL 88
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 3-111 7.86e-22

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 83.47  E-value: 7.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190    3 AKIRKNDLVEVVRGrtsdekalakrnarraeegleplkpGDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSAGG 82
Cdd:TIGR01079   1 MKIKKGDTVKVISG-------------------------KDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRQGG 55

                          90       100
                  ....*....|....*....|....*....
gi 512630190   83 IETIEAPIALSKVALVDPETKKRVRVGFR 111
Cdd:TIGR01079  56 IIEKEAPIHISNVMLFDPKTGKATRVGYR 84
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 8-97 1.11e-18

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 74.47  E-value: 1.11e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190   8 NDLVEVVRGRtsdekalakrnarraeegleplkpgDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSAGGIETIE 87
Cdd:cd06089    1 GDEVQVIRGK-------------------------DKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPQGGIIEVE 55

                         90
                 ....*....|
gi 512630190  88 APIALSKVAL 97
Cdd:cd06089   56 APIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 65-113 3.93e-16

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 67.47  E-value: 3.93e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 512630190   65 INLKTRHVRQGQQGSAGGIETIEAPIALSKVALVDPETKKRVRVGFRED 113
Cdd:pfam17136   1 VNMVKKHVKPSQQNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVGFKED 49
rpl24 CHL00141
ribosomal protein L24; Validated
 43-104 8.79e-13

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 59.66  E-value: 8.79e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 512630190  43 DKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSAGGIETIEAPIALSKVALVDPETKK 104
Cdd:CHL00141  22 DKGKIGEVLKIIKKSNKVIVKGINIKFKHIKPNKENEVGEIKQFEAPIHSSNVMLYNEESNI 83
rplX PRK12281
50S ribosomal protein L24; Reviewed
 4-98 2.15e-10

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 53.50  E-value: 2.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512630190   4 KIRKNDLVEVVRGRtsdekalakrnarraeegleplkpgDKGKQGRVIQVFPAEGKVLVEGINLKTRHVRQGQQGSAGGI 83
Cdd:PRK12281   6 KVKKGDMVKVIAGD-------------------------DKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNPNGGF 60

                         90
                 ....*....|....*
gi 512630190  84 ETIEAPIALSKVALV 98
Cdd:PRK12281  61 IEKEMPIHISNVKKV 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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