|
Name |
Accession |
Description |
Interval |
E-value |
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
8-614 |
0e+00 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 630.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 8 WKNLMVILVVAIGILYALPNLYGedpsvqvsgtrgqqasdetltqvqsalaslnitpkamnlengsilvrlnkdeeqlpa 87
Cdd:PRK05812 1 WKYLLILLVLLIGLLYALPNLRG--------------------------------------------------------- 23
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 88 kekiaevlgnnysvalNLAPATPEWLTSIGGEPMKRGLDLRGGVRFLMEVDMNTALAKQQDQLQDTLRNDFRKEKWQYKA 167
Cdd:PRK05812 24 ----------------ALAPATPEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDALKKRLESLADDLRSLLREKKIRYGG 87
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 168 VkkaenfatDVEFNDTDTADKAVRYIRRTNpnleatyisptvvrfAQSAQGLATSRDLAIEQNLSILRKRVEELGVSEPT 247
Cdd:PRK05812 88 V--------EITFRDAEDRDKAIALLRKLS---------------SLTEAELKEITEEALEQAIEIIRNRVNELGVAEPV 144
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 248 IQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVngnanlesaargivpadseikysrdgmptvlyrKTILGGEHII 327
Cdd:PRK05812 145 IQRQGADRIVVELPGVQDTARAKEILGKTATLEFRLV---------------------------------PVILTGDDIT 191
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 328 NATSGKDERGLPNVSINLDAQGGDLMSNATKSAVGKPMATLYsefkdsgrrdangkvilekHEEVINVATINSRL-GSSF 406
Cdd:PRK05812 192 DASASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVL-------------------DGEVISAPVIQSAItGGSA 252
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 407 QITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATAALLAN 486
Cdd:PRK05812 253 QITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVAN 332
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 487 LVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIIL 566
Cdd:PRK05812 333 LVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIIL 412
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 514061374 567 YSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYG-GKRVKKLWI 614
Cdd:PRK05812 413 YALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLLYGrRKRLKKLSI 461
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
85-614 |
0e+00 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 542.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 85 LPAKEKIAEVLGNNYSVALNLapatpeWLTSIGGEPMKRGLDLRGGVRFLMEVDMNTALAKQQDQLQDTlrndfrkekwq 164
Cdd:COG0342 1 MKAKFLLWRLLLLLLVVALSL------VAPNGPAKPIKLGLDLQGGVHLLLEVDTDAALDEDGDGIREV----------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 165 ykavkkaenfatdvefndtdtadkavryirrtnpnleatyisptvvrfaqsaqglatsRDLAIEQNLSILRKRVEELGVS 244
Cdd:COG0342 64 ----------------------------------------------------------TEEALDQAIEILRNRVNELGVS 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 245 EPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVNGNAnlesAARGIVPADSEIKYSRDGMPTVLYRKTILGGE 324
Cdd:COG0342 86 EPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVDDSA----DAQAAVPAGSELLPCRDGQPYLLLGPVVLTGD 161
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 325 HIINATSGKD-ERGLPNVSINLDAQGGDLMSNATKSAVGKPMATLYsefkdsgrrDangkvilekhEEVINVATINSRL- 402
Cdd:COG0342 162 DLTDASAGFDqQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVL---------D----------GEVISAPVIQEPIt 222
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 403 GSSFQITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATAA 482
Cdd:COG0342 223 GGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIA 302
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 483 LLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILV 562
Cdd:COG0342 303 LALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIA 382
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 514061374 563 AIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYGGKRVKKLWI 614
Cdd:COG0342 383 AVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKKLGI 434
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
124-600 |
3.56e-162 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 469.46 E-value: 3.56e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 124 GLDLRGGVRFLMEVDMNTALakqqdqlqdtlrndfrkekwqykavkkaENFATDVEFNDTdtadkavryirrtnpnleat 203
Cdd:TIGR01129 2 GLDLRGGARVLLEVDMSTAV----------------------------VLKLSEAEVNAI-------------------- 33
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 204 yisptvvrfaqsaqglatsRDLAIEQNLSILRKRVEELGVSEPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRL 283
Cdd:TIGR01129 34 -------------------RKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAKDILGGTATLEFRL 94
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 284 VNGNA-NLESAARGIVPADSEIKYSRDGMP--TVLYRKTILGGEHIINATSGKDER-GLPNVSINLDAQGGDLMSNATKS 359
Cdd:TIGR01129 95 VDDEStSPDDALAGNVPAGSELLDSRSGDPkyYLLKKSPVLTGDHITDATSSVDQRsGQPVVSFSLDSEGARIFGDFTQA 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 360 AVGKPMATLYSEfkdsgrrdangkvilekheEVINVATINSRL-GSSFQITGINSAAEAQNLAVLLRSGALIAPIVIVEE 438
Cdd:TIGR01129 175 NIGKRLAIVLDN-------------------KVVSAPTIQEAItGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEE 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 439 RTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSID 518
Cdd:TIGR01129 236 RTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVD 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 519 ANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRM 598
Cdd:TIGR01129 316 ANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRL 395
|
..
gi 514061374 599 LV 600
Cdd:TIGR01129 396 LL 397
|
|
| SecD-TM1 |
pfam13721 |
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane ... |
2-103 |
2.76e-43 |
|
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane region of the SecD export protein. SecD is directly involved in protein secretion and important for the release of proteins that have been translocated across the cytoplasmic membrane.
Pssm-ID: 463968 [Multi-domain] Cd Length: 103 Bit Score: 150.36 E-value: 2.76e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 2 LNRFPLWKNLMVILVVAIGILYALPNLYGEDPSVQVSGTRG-QQASDETLTQVQSALASLNITPKAMNLENGSILVRLNK 80
Cdd:pfam13721 1 MNRYPLWKYLLILVVLLIGLLYALPNLYGEDPAVQISAARGgAKVDEATLDRVEQALKAAGIPVKSIELEGDSLLVRFDS 80
|
90 100
....*....|....*....|...
gi 514061374 81 DEEQLPAKEKIAEVLGNNYSVAL 103
Cdd:pfam13721 81 TDDQLKAKDVLQRALGDDYVVAL 103
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
456-611 |
4.12e-18 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 88.68 E-value: 4.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 456 ASMLGLGL----TILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEI 531
Cdd:NF037998 446 ASIIFLLIlaiaIMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHL 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 532 -RNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYGGKRVK 610
Cdd:NF037998 526 yKNKRSIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQWFK 605
|
.
gi 514061374 611 K 611
Cdd:NF037998 606 K 606
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
433-593 |
2.68e-13 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 68.79 E-value: 2.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 433 IVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYK-VFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVL 511
Cdd:pfam02355 13 AEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 512 AVGMSIDANVLIYERIKEEIR--NGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISM 589
Cdd:pfam02355 93 IIGYSVNDTVVVFDRVRENLRkkTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIVGT 172
|
....
gi 514061374 590 FTAI 593
Cdd:pfam02355 173 YSSI 176
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
439-599 |
6.44e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 39.61 E-value: 6.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 439 RTIGASLgaDNVAQGMdasMLGLGLTILfcVVYYKVFGLFAT----AALLANLVLTIGLMSLIGATLTMPGIAGIVLAVG 514
Cdd:NF033617 323 RFIRASI--DEVESTL---LEAVALVIL--VVFLFLRNLRATlipaVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIG 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 515 MSIDANVLIYERIKEEIRNGRSIQQAIHEGYNG-AFTSIfdsNLTTILVAI---ILYSVG-TGPV-KGFAVTLALGVMIS 588
Cdd:NF033617 396 LVVDDAIVVVENIHRHIEEGESPLEAALKGAREiGFTVI---AMTLTLVAVylpILFMGGlTGRLfREFAVTLAGAVIIS 472
|
170
....*....|.
gi 514061374 589 MFTAITGTRML 599
Cdd:NF033617 473 GIVALTLTPMM 483
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
8-614 |
0e+00 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 630.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 8 WKNLMVILVVAIGILYALPNLYGedpsvqvsgtrgqqasdetltqvqsalaslnitpkamnlengsilvrlnkdeeqlpa 87
Cdd:PRK05812 1 WKYLLILLVLLIGLLYALPNLRG--------------------------------------------------------- 23
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 88 kekiaevlgnnysvalNLAPATPEWLTSIGGEPMKRGLDLRGGVRFLMEVDMNTALAKQQDQLQDTLRNDFRKEKWQYKA 167
Cdd:PRK05812 24 ----------------ALAPATPEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDALKKRLESLADDLRSLLREKKIRYGG 87
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 168 VkkaenfatDVEFNDTDTADKAVRYIRRTNpnleatyisptvvrfAQSAQGLATSRDLAIEQNLSILRKRVEELGVSEPT 247
Cdd:PRK05812 88 V--------EITFRDAEDRDKAIALLRKLS---------------SLTEAELKEITEEALEQAIEIIRNRVNELGVAEPV 144
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 248 IQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVngnanlesaargivpadseikysrdgmptvlyrKTILGGEHII 327
Cdd:PRK05812 145 IQRQGADRIVVELPGVQDTARAKEILGKTATLEFRLV---------------------------------PVILTGDDIT 191
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 328 NATSGKDERGLPNVSINLDAQGGDLMSNATKSAVGKPMATLYsefkdsgrrdangkvilekHEEVINVATINSRL-GSSF 406
Cdd:PRK05812 192 DASASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVL-------------------DGEVISAPVIQSAItGGSA 252
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 407 QITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATAALLAN 486
Cdd:PRK05812 253 QITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVAN 332
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 487 LVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIIL 566
Cdd:PRK05812 333 LVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIIL 412
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 514061374 567 YSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYG-GKRVKKLWI 614
Cdd:PRK05812 413 YALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLLYGrRKRLKKLSI 461
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
2-605 |
0e+00 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 589.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 2 LNRFPLWKNLMVILVVAIGILYALPNLYGEDPSVQVSGTRGQQASDETLTQVqsaLASLNITPKAMNLENGSILVRLNKD 81
Cdd:PRK12933 10 LNHYSAWKYVVLIVTIIILLLSAIPTWYGEDAAVQVSAKAGLLLNVVELRQL---LQAQGINVKRIDQKEGKTLIVLDDD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 82 EEQLPAKEKIAEVLGNNYSVALNLAPATPEWLTSIGGEPMKRGLDLRGGVRFLMEVDMNTALAKQQDQLQDTLRNDFRKE 161
Cdd:PRK12933 87 SQQSQAKTLLSSMVKEPKELTLSLASAAPKWLQNMGFSPIKLGLDLRGGVQFLLDVDVDPVYQEQRDALVDSVRQFLREQ 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 162 KWQYKAVKKAENFATDVEFNDTDTADKAVRYIRRTNPNLEATYISPTVVRFAQSAQGLATSRDLAIEQNLSILRKRVEEL 241
Cdd:PRK12933 167 RIRGVSVRLDDSDQLAVTTPDNDARSAVRQFIQQNYPGWQVTNSDDRGLQLKLSQQEKTKFRNLTVQQNLQIMRSRIEEL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 242 GVSEPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVNGnanlESAARGIVPADseikysRDGMPTVLYRKTIL 321
Cdd:PRK12933 247 GITEALVQRQGEHRIRIELPGVQDPAAAKNVIGATASLAFYEVKE----SGSVNAKVLKD------KNGRPVYVARRPVL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 322 GGEHIINATSGKDERGLPNVSINLDAQGGDLMSNATKSAVGKPMATLYSEFKdsgrRDANGKVilEKHEEVINVATINSR 401
Cdd:PRK12933 317 GGEHIVDARASLGEMGMAEVNISLDRAGGKKMSDFSRDNIGKPMATSYSEYS----RDEQGKT--KQSEEVISVATIQSQ 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 402 LGSSFQITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATA 481
Cdd:PRK12933 391 LGDRFRITGAGSYQEAQQLALLLRAGSLTAPVTIVEERTIGPSLGAENIENGFAALALGMGITLLFMALWYRRLGWVANV 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 482 ALLANLVLTIGLMSLI-GATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTI 560
Cdd:PRK12933 471 ALIANMVCLFGLLALIpGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQAIDTGFDSAFSTIFDANFTTM 550
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 514061374 561 LVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYG 605
Cdd:PRK12933 551 ITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALINLVYG 595
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
85-614 |
0e+00 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 542.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 85 LPAKEKIAEVLGNNYSVALNLapatpeWLTSIGGEPMKRGLDLRGGVRFLMEVDMNTALAKQQDQLQDTlrndfrkekwq 164
Cdd:COG0342 1 MKAKFLLWRLLLLLLVVALSL------VAPNGPAKPIKLGLDLQGGVHLLLEVDTDAALDEDGDGIREV----------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 165 ykavkkaenfatdvefndtdtadkavryirrtnpnleatyisptvvrfaqsaqglatsRDLAIEQNLSILRKRVEELGVS 244
Cdd:COG0342 64 ----------------------------------------------------------TEEALDQAIEILRNRVNELGVS 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 245 EPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVNGNAnlesAARGIVPADSEIKYSRDGMPTVLYRKTILGGE 324
Cdd:COG0342 86 EPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVDDSA----DAQAAVPAGSELLPCRDGQPYLLLGPVVLTGD 161
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 325 HIINATSGKD-ERGLPNVSINLDAQGGDLMSNATKSAVGKPMATLYsefkdsgrrDangkvilekhEEVINVATINSRL- 402
Cdd:COG0342 162 DLTDASAGFDqQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVL---------D----------GEVISAPVIQEPIt 222
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 403 GSSFQITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATAA 482
Cdd:COG0342 223 GGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIA 302
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 483 LLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILV 562
Cdd:COG0342 303 LALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIA 382
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 514061374 563 AIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYGGKRVKKLWI 614
Cdd:COG0342 383 AVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKKLGI 434
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
124-600 |
3.56e-162 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 469.46 E-value: 3.56e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 124 GLDLRGGVRFLMEVDMNTALakqqdqlqdtlrndfrkekwqykavkkaENFATDVEFNDTdtadkavryirrtnpnleat 203
Cdd:TIGR01129 2 GLDLRGGARVLLEVDMSTAV----------------------------VLKLSEAEVNAI-------------------- 33
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 204 yisptvvrfaqsaqglatsRDLAIEQNLSILRKRVEELGVSEPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRL 283
Cdd:TIGR01129 34 -------------------RKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAKDILGGTATLEFRL 94
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 284 VNGNA-NLESAARGIVPADSEIKYSRDGMP--TVLYRKTILGGEHIINATSGKDER-GLPNVSINLDAQGGDLMSNATKS 359
Cdd:TIGR01129 95 VDDEStSPDDALAGNVPAGSELLDSRSGDPkyYLLKKSPVLTGDHITDATSSVDQRsGQPVVSFSLDSEGARIFGDFTQA 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 360 AVGKPMATLYSEfkdsgrrdangkvilekheEVINVATINSRL-GSSFQITGINSAAEAQNLAVLLRSGALIAPIVIVEE 438
Cdd:TIGR01129 175 NIGKRLAIVLDN-------------------KVVSAPTIQEAItGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEE 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 439 RTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSID 518
Cdd:TIGR01129 236 RTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVD 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 519 ANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRM 598
Cdd:TIGR01129 316 ANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRL 395
|
..
gi 514061374 599 LV 600
Cdd:TIGR01129 396 LL 397
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
224-613 |
1.36e-127 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 393.06 E-value: 1.36e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 224 DLAIEQNLSILRKRVEELGVSEPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVNGNANLESAARGIVPADse 303
Cdd:PRK13024 58 REALDSTVEVLRNRIDGLGVSEPNIQREGNNRIRVELPGVQDPERARELLGSTAKLTFRDVTDPPPPGVGGPVVGPDE-- 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 304 ikysrdGMPTVLYRKTILGGEHIINATSGKDER--GLPNVSINLDAQGGDLMSNATKSAVGKPmatlysefkDSGRRDAn 381
Cdd:PRK13024 136 ------GKDTAVLNPVLLSGDDLTDAGAKFDQDqtNRPSVSLKLKSEGAKKWAKVTEKNSKKG---------PPNNRIA- 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 382 gkVILEKheEVINVATINS-RLGSSFQITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLG 460
Cdd:PRK13024 200 --IVLDP--KVISAPTVNQpINGGSVQISGNFTVEEAKDLANLLNAGALPAPLKIIESRSVGPTLGQDAIDAGIIAGIIG 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 461 LGLTILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQA 540
Cdd:PRK13024 276 FALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKA 355
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 514061374 541 IHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLvYGGKRVKKLW 613
Cdd:PRK13024 356 FKKGFKNAFSTILDSNITTLIAAAILFFFGTGPVKGFATTLIIGILASLFTAVFLTRLLLEL-LVKRGDKKPF 427
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
1-612 |
1.07e-110 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 351.71 E-value: 1.07e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 1 MLnRFPLWKNLMVILVVAIGILYALPNLYGEdpsvqvsgtrgqqasdetltqvqSALASLnitpkamnlengsilvrlnk 80
Cdd:PRK14726 1 ML-HFSRWKTILIWLVVLAGVAIAAPNLLSE-----------------------AQLASL-------------------- 36
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 81 deeqlpakekiaevlgnnysvalnlapatPEWLTSiggEPMKRGLDLRGGVRFLMEVDMNTALAKQQDQLQDTLRNDFRK 160
Cdd:PRK14726 37 -----------------------------PSWLPH---RQVTLGLDLQGGSHIVLKVERSDIVKDRLEETVANIRNALRD 84
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 161 EKWQYKAVKKAENFATdVEFNDTDTADKAVRYIR-------------RTNPNLEATYISPTVVRFAQSAQGLATSRDLAI 227
Cdd:PRK14726 85 AGIRYTGLTGNGQTVQ-VRITDPAQTQAAVDALKpltapvsagglggSSIQELTLQEGGEGQLRLQLTDAGIDYRVSSAL 163
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 228 EQNLSILRKRVEELGVSEPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVNGNANLESAARGIVPADSEIKYS 307
Cdd:PRK14726 164 TQSIEVVRRRVAELGTTEPLIRRQGDDRIVVQVPGLVDPQRLKNLLNQPAKLSFRLVDSSMPAQEALNGRPPATSEVLYS 243
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 308 RDG--MPTVLYRKTILGGEHIINATSGKDER-GLPNVSINLDAQGGDLMSNATKSAVGKPMAtlysefkdsgrrdangkV 384
Cdd:PRK14726 244 LDDppVPYLVERRAFVSGENLVDAQPVFDPQtNEPVVTFRLDAEGTQRFAQATQQNVGKHFA-----------------I 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 385 ILEKHeeVINVATINSR-LGSSFQITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLGLGL 463
Cdd:PRK14726 307 VLDGQ--VISAPVIDEAiTGGEGRISGNFSEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLIAAIL 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 464 TILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHE 543
Cdd:PRK14726 385 VAALMIGFYGFLGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDR 464
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 514061374 544 GYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYGGKRVKKL 612
Cdd:PRK14726 465 GFSRALATIVDANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLVAVWLRRRRPKHL 533
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
227-600 |
4.08e-65 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 227.58 E-value: 4.08e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 227 IEQNLSILRKRVEELGVSEPTIQRQGADRIVVELPGVQDTARAKEILGATATLEFRLVNGNANLESAARGIVPADSEIKY 306
Cdd:PRK13023 69 LETTANIMRQRLEELGYGNPVVEGEGRNQIRVEVPGLYDAQLLKDILTIRGNLSFRAMDDTMSPDDAIRGTPPADSEIVY 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 307 SRDGMPT--VLYRKTILGGEHIINATSG-KDERGLPNVSINLDAQGGDLMSNATKSAVGKPMATLYSEfkdsgrrdangk 383
Cdd:PRK13023 149 SFDDPPVgyLLKKTPILTGHDITDAKASiSADDGQPVITLTLDDNGRRRLADLTAQGNENSFAIVVDN------------ 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 384 vilekheEVINVATINSRLGSS-FQITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLGLG 462
Cdd:PRK13023 217 -------QVVSAPTVSGPLDTSeLQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAAL 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 463 LTILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIH 542
Cdd:PRK13023 290 VVGLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAME 369
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 514061374 543 EGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLV 600
Cdd:PRK13023 370 SGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLI 427
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
439-593 |
9.50e-54 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 181.69 E-value: 9.50e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 439 RTIGASLGADNVAQGMDASMLGLGLTILFCVVYYKVFGLFATAALLAN-LVLTIGLMSLIGATLTMPGIAGIVLAVGMSI 517
Cdd:TIGR00916 35 GTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSV 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 514061374 518 DANVLIYERIKEEIR--NGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAI 593
Cdd:TIGR00916 115 DDTVVIFDRIREELRkyKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
375-597 |
3.25e-48 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 181.98 E-value: 3.25e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 375 SGRRDANGKVILEKHeeVINVATINSRLGSSFQITGINSAAEAQNLAVLLRSGAL-IAPIVIVEErTIGASLGADNVAQG 453
Cdd:PRK12911 835 SGGRGWRMAVVLDGY--VVSDPVLNVPLKDHASVSGKFSHREVHRLATDLKSGAMsFVPEVLSEE-VISPELGKSQRTQG 911
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 454 MDASMLGLGLTILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRN 533
Cdd:PRK12911 912 IISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERIREEYLL 991
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 514061374 534 GRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTR 597
Cdd:PRK12911 992 SRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTK 1055
|
|
| SecD-TM1 |
pfam13721 |
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane ... |
2-103 |
2.76e-43 |
|
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane region of the SecD export protein. SecD is directly involved in protein secretion and important for the release of proteins that have been translocated across the cytoplasmic membrane.
Pssm-ID: 463968 [Multi-domain] Cd Length: 103 Bit Score: 150.36 E-value: 2.76e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 2 LNRFPLWKNLMVILVVAIGILYALPNLYGEDPSVQVSGTRG-QQASDETLTQVQSALASLNITPKAMNLENGSILVRLNK 80
Cdd:pfam13721 1 MNRYPLWKYLLILVVLLIGLLYALPNLYGEDPAVQISAARGgAKVDEATLDRVEQALKAAGIPVKSIELEGDSLLVRFDS 80
|
90 100
....*....|....*....|...
gi 514061374 81 DEEQLPAKEKIAEVLGNNYSVAL 103
Cdd:pfam13721 81 TDDQLKAKDVLQRALGDDYVVAL 103
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
232-590 |
2.77e-26 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 111.51 E-value: 2.77e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 232 SILRKRVEELGVSEPTIQRQGADRIVVELPGVqDTARAKEILGAtatlefrlvngnanlesaaRGIVPAdsEIKYSRDGM 311
Cdd:PRK08343 70 EILESRLNALGLKDIKVYPVGDQYIVVEVPGV-DADTAKEIIEK-------------------QGVFEA--RIQTPGNNN 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 312 PTVLYRKTILGgehiINATSGKDERGLPNVSINLDAQGGDLMSNAtksAVGKPMAtlysefkdsgRRDANGKVILEKHEE 391
Cdd:PRK08343 128 ETVLTGDDIES----VGSPSQDPSGGAWGVPFTLSEDGAEKFAEV---AKGKGAT----------DDPSGHPLDMYLDGE 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 392 VINVATINSRLGSS-----------FQITGINSAAEAQNLAVLLRSGALIAPIVIVEERTIGASLGADNVAQGMDASMLG 460
Cdd:PRK08343 191 LIYAAPLSPDLASGlasgpvvitvgSTGTTEEAKEEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQFKKGSLIAGLLA 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 461 LgLTILFcVVYYK------VFGLFATAalLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIY-ERIKEEIRN 533
Cdd:PRK08343 271 L-LAVAL-VVFLRyrepriALPMVITS--LSEVIIILGFAALIGWQLDLASIAGIIAVIGTGVDDLIIITdEVLHEGKVP 346
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 514061374 534 GRSIQQAiheGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMF 590
Cdd:PRK08343 347 SRKVFLS---RIKRAFFIIFAAAATTIAAMSPLAVMGLGDLKGFAITTILGVLIGVL 400
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
456-611 |
4.12e-18 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 88.68 E-value: 4.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 456 ASMLGLGL----TILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEI 531
Cdd:NF037998 446 ASIIFLLIlaiaIMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHL 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 532 -RNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNLVYGGKRVK 610
Cdd:NF037998 526 yKNKRSIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQWFK 605
|
.
gi 514061374 611 K 611
Cdd:NF037998 606 K 606
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
448-594 |
2.65e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 76.44 E-value: 2.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 448 DNVAQGMDASM-LGLGLTILFCVVYYK--VFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIY 524
Cdd:COG1033 601 ESVIESQIRSLlLALLLIFLLLLLAFRslRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFL 680
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 525 ERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAIT 594
Cdd:COG1033 681 SRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGLLVALLAALL 750
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
450-594 |
3.15e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 76.05 E-value: 3.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 450 VAQGMDASM-----LGLGLTILFCVVYYK--VFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVL 522
Cdd:COG1033 212 IAEAIQSDLaiffpLALLLILLLLFLFFRslRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIH 291
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 514061374 523 IYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAIT 594
Cdd:COG1033 292 LLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLT 363
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
433-593 |
2.68e-13 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 68.79 E-value: 2.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 433 IVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYK-VFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVL 511
Cdd:pfam02355 13 AEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 512 AVGMSIDANVLIYERIKEEIR--NGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISM 589
Cdd:pfam02355 93 IIGYSVNDTVVVFDRVRENLRkkTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIVGT 172
|
....
gi 514061374 590 FTAI 593
Cdd:pfam02355 173 YSSI 176
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
432-592 |
5.80e-13 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 69.70 E-value: 5.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 432 PIVIVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYK-VFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIV 510
Cdd:COG0341 114 DVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEwRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALL 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 511 LAVGMSIDANVLIYERIKEEIRN--GRSIQQAIHEGYNGAFT-SIFDSnLTTILVAIILYSVGTGPVKGFAVTLALGVMI 587
Cdd:COG0341 194 TIIGYSLNDTVVVFDRIRENLRKyrKMTLAEIINLSINQTLSrTINTS-LTTLLVVLALLFFGGETLRDFALALLIGIIV 272
|
....*....
gi 514061374 588 ----SMFTA 592
Cdd:COG0341 273 gtysSIFIA 281
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
435-593 |
6.28e-13 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 68.84 E-value: 6.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 435 IVEERTIGASLGADNVAQGMDASMLGLGLTILFCVVYYK-VFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAV 513
Cdd:TIGR00966 82 IRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEwRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTII 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 514 GMSIDANVLIYERIKEEIR--NGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFT 591
Cdd:TIGR00966 162 GYSINDTVVVFDRIRENLRkyTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVGTYS 241
|
..
gi 514061374 592 AI 593
Cdd:TIGR00966 242 SI 243
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
440-611 |
1.02e-11 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 67.95 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 440 TIGASLGADNVAQGMDASMLGLGLTILFCVVYYKV-FGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSID 518
Cdd:PRK13024 566 TVGPTVGKELARNAIIAVLIALIGILLYILIRFEWtFSLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSIN 645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 519 ANVLIYERIKEEIRN--GRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAI-TG 595
Cdd:PRK13024 646 DTVVVFDRIRENLRLykKKDLREIVNKSINQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIfIA 725
|
170
....*....|....*.
gi 514061374 596 TRMLVNLvyGGKRVKK 611
Cdd:PRK13024 726 APLWLDL--EKRRLKK 739
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
438-614 |
1.11e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 58.31 E-value: 1.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 438 ERTIGASLGadnVAQGMDASMLGLGLTILFCVVYYKVFGLfatAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSI 517
Cdd:TIGR00921 188 EREFGKDMG---TTMAISGILVVLVLLLDFKRWWRPLLPL---VIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 518 DANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTR 597
Cdd:TIGR00921 262 DYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLP 341
|
170
....*....|....*..
gi 514061374 598 MLVNLVYGGKRVKKLWI 614
Cdd:TIGR00921 342 ALLQSIDIGREKVKKEI 358
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
442-594 |
1.26e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 57.85 E-value: 1.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 442 GASLGADNVAQGMD----ASMLGLGLTILFCVVyykVFGLFATAAL-----LANLVLTIGLMSLIGATLTMPGIA-GIVL 511
Cdd:COG2409 156 PAALAADLNEAFEEdlgrAELITLPVALVVLLL---VFRSLVAALLplltaGLAVGVALGLLALLAAFTDVSSFApNLLT 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 512 AVGM--SIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISM 589
Cdd:COG2409 233 MLGLgvGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAV 312
|
....*
gi 514061374 590 FTAIT 594
Cdd:COG2409 313 LAALT 317
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
475-593 |
3.55e-08 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 56.65 E-value: 3.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 475 FGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRS--IQQAIHEGYNGAFTSI 552
Cdd:PRK14726 697 FAVGAIIATLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKmpLPILIDASINQTLSRT 776
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 514061374 553 FDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAI 593
Cdd:PRK14726 777 VLTSATTLLALLALYLFGGEVIRSFTFAMLFGVAVGTFSSI 817
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
441-594 |
2.42e-07 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 52.94 E-value: 2.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 441 IGASLGADNVAQGmdasmlGLGLTI-LFCVVYYKVF------GLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAV 513
Cdd:PRK13021 116 VGPQVGQELAEQG------GLALLVaMLCILGYLSYrfewrlASGALFALVHDVIFVLAFFALTQMEFNLTVLAAVLAIL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 514 GMSIDANVLIYERIKEEIRNGR--SIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFT 591
Cdd:PRK13021 190 GYSLNDSIIIADRIRELLIAKPklAIQEINNQAIVATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFS 269
|
...
gi 514061374 592 AIT 594
Cdd:PRK13021 270 SIS 272
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
432-573 |
4.21e-07 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 51.86 E-value: 4.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 432 PIVIVEERTIGASLGADNVAQGMdasmLGLGLTILFCVVYykVFGLFAT--------AALLANLVLTIGLMSLIGATLTM 503
Cdd:PRK08578 115 SELNYSEKQIGPTFGSQFQEQAL----KAVGFAFIGMAVV--VFLIFRTpvpslaviLSAFSDIIIALALMNLFGIELSL 188
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 504 PGIAGIVLAVGMSIDANVLIYERIKEeiRNGRsiqqaIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGP 573
Cdd:PRK08578 189 ATVAALLMLIGYSVDSDILLTTRVLK--RRGT-----FDESIKRAMRTGITMTLTTIAAMAVLYIVSTIP 251
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
463-602 |
5.13e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 52.92 E-value: 5.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 463 LTILFCVVYYKVFGLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEiRNGRSIQQAIH 542
Cdd:TIGR00921 581 LMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAERYFEE-RKEHGPKEAIT 659
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 543 EGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAITGTRMLVNL 602
Cdd:TIGR00921 660 HTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLVL 719
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
420-610 |
7.88e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 51.52 E-value: 7.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 420 LAVLLRSgaLIAPIVIVeeRTIGASLGAdnvAQGmdasmlglgltilfcvvyykvfglfataallanLVLTIGLMSLIGA 499
Cdd:pfam03176 159 LLIVYRS--VVAALLPL--LTVGLSLGA---AQG---------------------------------LVAILAHILGIGL 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 500 TLTMPGIAGIVLaVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTtilVAIILYS---VGTGPVKG 576
Cdd:pfam03176 199 STFALNLLVVLL-IAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLT---VAIAMLAlsfARLPVFAQ 274
|
170 180 190
....*....|....*....|....*....|....
gi 514061374 577 FAVTLALGVMISMFTAITGTRMLvnLVYGGKRVK 610
Cdd:pfam03176 275 VGPTIAIGVLVDVLAALTLLPAL--LALLGRWGL 306
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
461-593 |
3.51e-06 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 50.00 E-value: 3.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 461 LGLTILFCVVYYKVFGLFATAALLANL---VLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRS- 536
Cdd:PRK13023 586 LSLIGIFIYVWFRFRWQLALGAVLSTLhdvVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSa 665
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 514061374 537 -IQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTAI 593
Cdd:PRK13023 666 pLPAIIDASINQTLSRTLLTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSI 723
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
458-599 |
8.97e-06 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 48.95 E-value: 8.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 458 MLGLGLTILfcVVYykVF------GLFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEI 531
Cdd:COG0841 338 LEAILLVVL--VVF--LFlrswraTLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVDDAIVVVENIERHM 413
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 514061374 532 RNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGtGPV----KGFAVTLALGVMISMFTAITGTRML 599
Cdd:COG0841 414 EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMG-GITgqlfRQFALTVAIALLISLFVALTLTPAL 484
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
456-592 |
1.26e-05 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 48.31 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 456 ASMLGLGLTILFCVVYYKVFG----LFATAALLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYErikeei 531
Cdd:COG4258 642 LWLLLLALLLILLLLLLRLRSlrraLRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTE------ 715
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 514061374 532 rngrsiQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTA 592
Cdd:COG4258 716 ------GLLDKGELARTLLSILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLLA 770
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
450-594 |
1.12e-04 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 45.37 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 450 VAQGMDasMLGLGLTILFCVVYY-------KVFGLFATaaLLANLVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVL 522
Cdd:TIGR03480 267 VSEGAT--VAGLLSFVLVLVLLWlalrsprLVFAVLVT--LIVGLILTAAFATLAVGHLNLISVAFAVLFIGLGVDFAIQ 342
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 514061374 523 IYERIKEEIRNGRSIQQAIHEGYNGAFTSIFdsnLTTILVAIILYSVGTGPVKGFA---VTLALGVMISMFTAIT 594
Cdd:TIGR03480 343 FSLRYREERFRGGNHREALSVAARRMGAALL---LAALATAAGFFAFLPTDYKGVSelgIIAGTGMFIALFVTLT 414
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
487-608 |
2.09e-04 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 44.59 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 487 LVLTIGLMSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIR-NGRSIQQAIHEGYNG-AFTSIFdsnLTTILVAI 564
Cdd:pfam00873 369 LLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVVENIERVLEeNGLKPLEAAYKSMGEiGGALVA---IALVLSAV 445
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 514061374 565 ILYSVGTGPVKG-----FAVTLALGVMISMFTAITGTRMLVNLVYGGKR 608
Cdd:pfam00873 446 FLPILFLGGLTGrifrqFAITIVLAILLSVLVALTLTPALCATLLKPRR 494
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
462-592 |
4.69e-04 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 43.42 E-value: 4.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 462 GLTILFCVVYYKVFGLFATAALLANLVL----TIGLMSLI-------GATLTMPGIAGIVLaVGMSIDANVLIYERIKEE 530
Cdd:TIGR00833 753 TLAIVFMILALLLRAPVAPIVLIGSVALsylwALGLSVLAfqhilgaELHWSVLAGVFVLL-VALGVDYNMLLVSRIKEE 831
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 514061374 531 IRNGrsIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGPVKGFAVTLALGVMISMFTA 592
Cdd:TIGR00833 832 SPAG--NRTGIIRALGSTGGVITAAGLVFAGTMAALASAQLTAIAQFGFTVGVGILLDTFIV 891
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
494-603 |
2.03e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 41.36 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 494 MSLIGATLTMPGIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDsnlTTILVAIILYSVG--- 570
Cdd:PRK09579 376 MQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVS---MTITLAAVYAPIGflt 452
|
90 100 110
....*....|....*....|....*....|....*.
gi 514061374 571 --TGPV-KGFAVTLALGVMISMFTAITGTRMLVNLV 603
Cdd:PRK09579 453 glTGALfKEFALTLAGAVIISGIVALTLSPMMCALL 488
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
435-599 |
3.56e-03 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 40.48 E-value: 3.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 435 IVEER--TIGASLgaDNVAQGMdasMLGLGLTILfcVVYYKVFGLFATA----ALLANLVLTIGLMSLIGATLTMPGIAG 508
Cdd:PRK10614 319 IAQDRspTIRASL--EEVEQTL---AISVALVIL--VVFLFLRSGRATLipavAVPVSLIGTFAAMYLCGFSLNNLSLMA 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 509 IVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYNGAFTSIFDSNLTTILVAIILYSVGTGP---VKGFAVTLALGV 585
Cdd:PRK10614 392 LTIATGFVVDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPgrlFREFAVTLSVAI 471
|
170
....*....|....
gi 514061374 586 MISMFTAITGTRML 599
Cdd:PRK10614 472 GISLLVSLTLTPMM 485
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
420-587 |
6.35e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 39.75 E-value: 6.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 420 LAVLLRSgaLIAPIVIVeeRTIGASLGAdnvaqgmdasmlGLGLTILFCVVYYKVFGlFATAALLAnlvltiglmsliga 499
Cdd:COG2409 534 LLLLFRS--VVAPLKAV--LTNLLSLGA------------ALGVLVLVFQHGWLLLG-FTPGPLDS-------------- 582
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 500 tlTMPgIAGIVLAVGMSIDANVLIYERIKEEIRNGRSIQQAIHEGYN---GAFTSifdsnlttilVAIILYSV----GTG 572
Cdd:COG2409 583 --FVP-LLLFVILFGLGMDYEVFLVSRIREEYDRGGGTREAVIRGLArtgRVITS----------AALIMAAVfaafATS 649
|
170
....*....|....*...
gi 514061374 573 PV---KGFAVTLALGVMI 587
Cdd:COG2409 650 PLvflKQIGFGLAVGVLL 667
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
439-599 |
6.44e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 39.61 E-value: 6.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 439 RTIGASLgaDNVAQGMdasMLGLGLTILfcVVYYKVFGLFAT----AALLANLVLTIGLMSLIGATLTMPGIAGIVLAVG 514
Cdd:NF033617 323 RFIRASI--DEVESTL---LEAVALVIL--VVFLFLRNLRATlipaVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIG 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514061374 515 MSIDANVLIYERIKEEIRNGRSIQQAIHEGYNG-AFTSIfdsNLTTILVAI---ILYSVG-TGPV-KGFAVTLALGVMIS 588
Cdd:NF033617 396 LVVDDAIVVVENIHRHIEEGESPLEAALKGAREiGFTVI---AMTLTLVAVylpILFMGGlTGRLfREFAVTLAGAVIIS 472
|
170
....*....|.
gi 514061374 589 MFTAITGTRML 599
Cdd:NF033617 473 GIVALTLTPMM 483
|
|
| |
