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Conserved domains on  [gi|514975355|ref|WP_016663560|]
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MULTISPECIES: hypothetical protein [Dermabacter]

Protein Classification

DUF3450 domain-containing protein( domain architecture ID 714851)

DUF3450 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3450 super family cl26418
Protein of unknown function (DUF3450); This family of proteins are functionally ...
 53-125 2.71e-04

Protein of unknown function (DUF3450); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 260 amino acids in length.


The actual alignment was detected with superfamily member pfam11932:

Pssm-ID: 432198 [Multi-domain]  Cd Length: 238  Bit Score: 39.91  E-value: 2.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 514975355   53 LFARVGATAETIDALIARNARIAQDQAEYQSRFDKLTSKHATLLEEYHRLLDQISDLDNQQAAYCHYQEELDK 125
Cdd:pfam11932   4 LLLASGALAATLDQALDLAEKAVAAAAQSQKKIDKWDDEKQELLAEYRALKAELESLEVYNRQLERLVASQEQ 76
 
Name Accession Description Interval E-value
DUF3450 pfam11932
Protein of unknown function (DUF3450); This family of proteins are functionally ...
 53-125 2.71e-04

Protein of unknown function (DUF3450); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 260 amino acids in length.


Pssm-ID: 432198 [Multi-domain]  Cd Length: 238  Bit Score: 39.91  E-value: 2.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 514975355   53 LFARVGATAETIDALIARNARIAQDQAEYQSRFDKLTSKHATLLEEYHRLLDQISDLDNQQAAYCHYQEELDK 125
Cdd:pfam11932   4 LLLASGALAATLDQALDLAEKAVAAAAQSQKKIDKWDDEKQELLAEYRALKAELESLEVYNRQLERLVASQEQ 76
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 27-112 4.08e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 36.97  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514975355    27 DQVDELvDKAVRAELDSTDLHIETDQLFARVGATAETIDALIARNARIAQDQAEYQSRFDKLTSKHATLLEEYHRLLDQI 106
Cdd:TIGR02169  931 EELSEI-EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERI 1009


                   ....*.
gi 514975355   107 SDLDNQ 112
Cdd:TIGR02169 1010 EEYEKK 1015
 
Name Accession Description Interval E-value
DUF3450 pfam11932
Protein of unknown function (DUF3450); This family of proteins are functionally ...
 53-125 2.71e-04

Protein of unknown function (DUF3450); This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 260 amino acids in length.


Pssm-ID: 432198 [Multi-domain]  Cd Length: 238  Bit Score: 39.91  E-value: 2.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 514975355   53 LFARVGATAETIDALIARNARIAQDQAEYQSRFDKLTSKHATLLEEYHRLLDQISDLDNQQAAYCHYQEELDK 125
Cdd:pfam11932   4 LLLASGALAATLDQALDLAEKAVAAAAQSQKKIDKWDDEKQELLAEYRALKAELESLEVYNRQLERLVASQEQ 76
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 27-112 4.08e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 36.97  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514975355    27 DQVDELvDKAVRAELDSTDLHIETDQLFARVGATAETIDALIARNARIAQDQAEYQSRFDKLTSKHATLLEEYHRLLDQI 106
Cdd:TIGR02169  931 EELSEI-EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERI 1009


                   ....*.
gi 514975355   107 SDLDNQ 112
Cdd:TIGR02169 1010 EEYEKK 1015
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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