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Conserved domains on  [gi|515516534|ref|WP_016949788|]
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terminase large subunit domain-containing protein [Anabaena sp. PCC 7108]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG4373 super family cl24113
Mu-like prophage FluMu protein gp28 [Mobilome: prophages, transposons];
6-430 9.22e-54

Mu-like prophage FluMu protein gp28 [Mobilome: prophages, transposons];


The actual alignment was detected with superfamily member COG4373:

Pssm-ID: 443501 [Multi-domain]  Cd Length: 512  Bit Score: 187.03  E-value: 9.22e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   6 LYDYEKLWLKDKNRFKIGMFARQTGKTFTTTLE-VVDSCFASQAMGRKKrWVIlSRGERQAKE-----AMdegiklHSKA 79
Cdd:COG4373   27 LLPYQQRWIADESPLKIAEKSRRTGLTWAEAADdVLTAAAARSAGGMNV-FYI-GYNKDMAREfidacAM------WAKA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  80 YSL---TIESLDYEWEGTEGSHKALEVSFSNGSKITALPANPDTARGFSASVLLDEFAFHKDSRKIWTALFPVISAGHDL 156
Cdd:COG4373   99 FNLaasEIEEFVFEDQGEDKDILAFRIRFASGFRIQALSSNPSNLRGKQGNVVIDEAAFHEDLAELLKAALALLMWGGKV 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 157 RVVSTPNGKGNKFYDLVT---AEDPIWSKHIVDIYQAVEQGLPRdieelRRALNDEDAWAQEYELKWLDE---------- 223
Cdd:COG4373  179 RIISTHNGVDNPFNELIRdirAGKKDYSVHRITFDDAVADGLYE-----RICLVTGKPWSPEAEAAWRADiradygddad 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 224 ----------ASAWLSYDLINA------------VEDDYAGIPDLY---------------------TGGPCFIGNDIGL 260
Cdd:COG4373  254 eeldcipkdgGGAYLPRALIEAcmsadipvlrweGPDDFNLRPELEreaemadwceehleplldaldPGLRHALGEDFAR 333
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 261 RRDLWVAWVWE-KVGDVFWCREVQTLKRSTFAEHDDCLDELMKK-YKVVRLCMDQSGMGEKPVQDAQRRYGMLRTEGVLF 338
Cdd:COG4373  334 SGDLSVIWPLEiQQDLRRRVPFLVELRNVPFDQQEQILFYILDRlPRFAGGALDATGNGQYLAEAAAQRYGAERVEEVML 413
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 339 TNTNKLVLATIGKQKFEDRKVRIPMgDSNLRSDLHSLKKLptptGGV-RFDADATE-----NGHADRAWAAFLGLYAGAN 412
Cdd:COG4373  414 SEAWYRENMPPFKAAFEDGTLTIPK-DEDVLDDLRAVQLV----RGVpRVPDGRTKgadggKRHGDSAIALALAYYASRQ 488
                        490
                 ....*....|....*...
gi 515516534 413 PGSPIEFQALGQKRLGFG 430
Cdd:COG4373  489 DGGPIEYASVPRRRAAAR 506
 
Name Accession Description Interval E-value
COG4373 COG4373
Mu-like prophage FluMu protein gp28 [Mobilome: prophages, transposons];
6-430 9.22e-54

Mu-like prophage FluMu protein gp28 [Mobilome: prophages, transposons];


Pssm-ID: 443501 [Multi-domain]  Cd Length: 512  Bit Score: 187.03  E-value: 9.22e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   6 LYDYEKLWLKDKNRFKIGMFARQTGKTFTTTLE-VVDSCFASQAMGRKKrWVIlSRGERQAKE-----AMdegiklHSKA 79
Cdd:COG4373   27 LLPYQQRWIADESPLKIAEKSRRTGLTWAEAADdVLTAAAARSAGGMNV-FYI-GYNKDMAREfidacAM------WAKA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  80 YSL---TIESLDYEWEGTEGSHKALEVSFSNGSKITALPANPDTARGFSASVLLDEFAFHKDSRKIWTALFPVISAGHDL 156
Cdd:COG4373   99 FNLaasEIEEFVFEDQGEDKDILAFRIRFASGFRIQALSSNPSNLRGKQGNVVIDEAAFHEDLAELLKAALALLMWGGKV 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 157 RVVSTPNGKGNKFYDLVT---AEDPIWSKHIVDIYQAVEQGLPRdieelRRALNDEDAWAQEYELKWLDE---------- 223
Cdd:COG4373  179 RIISTHNGVDNPFNELIRdirAGKKDYSVHRITFDDAVADGLYE-----RICLVTGKPWSPEAEAAWRADiradygddad 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 224 ----------ASAWLSYDLINA------------VEDDYAGIPDLY---------------------TGGPCFIGNDIGL 260
Cdd:COG4373  254 eeldcipkdgGGAYLPRALIEAcmsadipvlrweGPDDFNLRPELEreaemadwceehleplldaldPGLRHALGEDFAR 333
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 261 RRDLWVAWVWE-KVGDVFWCREVQTLKRSTFAEHDDCLDELMKK-YKVVRLCMDQSGMGEKPVQDAQRRYGMLRTEGVLF 338
Cdd:COG4373  334 SGDLSVIWPLEiQQDLRRRVPFLVELRNVPFDQQEQILFYILDRlPRFAGGALDATGNGQYLAEAAAQRYGAERVEEVML 413
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 339 TNTNKLVLATIGKQKFEDRKVRIPMgDSNLRSDLHSLKKLptptGGV-RFDADATE-----NGHADRAWAAFLGLYAGAN 412
Cdd:COG4373  414 SEAWYRENMPPFKAAFEDGTLTIPK-DEDVLDDLRAVQLV----RGVpRVPDGRTKgadggKRHGDSAIALALAYYASRQ 488
                        490
                 ....*....|....*...
gi 515516534 413 PGSPIEFQALGQKRLGFG 430
Cdd:COG4373  489 DGGPIEYASVPRRRAAAR 506
Terminase_6N pfam03237
Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal ...
24-234 9.31e-26

Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal domain of terminase large subunits found in a variety of the Caudovirales and prophage regions of bacterial genomes. It includes the terminase large subunit of Bacteriophage T4 (terminase gene 17, Gp17). homologs are also found in Gene Transfer Agents (GTA), including ORFg2 (RCAP_rcc01683) of the GTA of Rhodobacter capsulatus (Rhodopseudomonas capsulata).


Pssm-ID: 427210 [Multi-domain]  Cd Length: 214  Bit Score: 104.04  E-value: 9.31e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   24 MFARQTGKTFTTTLEvvdscFASQAMGRK-KRWVILSRGERQAKEAMDEGiklHSKAYSLTIESLDYEWEGtegsHKALE 102
Cdd:pfam03237   2 LGGRQSGKTFAGARE-----LLRHALGRGpENQIILSASKGQAREEGGEF---PKGIIELARDLLDPDFEE----SNKGS 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  103 VSFSNGSKITALPANPDTARGF----SASVLLDEFAFHKDSRKIWTALFPVISAGHD-LRVVSTPNGKGNKFYDLVT--- 174
Cdd:pfam03237  70 IVLSNGASLHFLSLNASTAGGYrgaqIDAIYFDEFAWIPKFQESWKVTRLRATLGTDtKTFITTPPTPLHGVYDFWTgwl 149
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515516534  175 ------AEDPIWSKHIVDIYQAVEQGLPRdIEELrRALNDEDAWAQEYELKWLDEASAWLSYDLIN 234
Cdd:pfam03237 150 eekgppSYVKIPATVEATIEDAVKLGEDL-IEEL-EALYSPDEFAQLLLGEFIDTSGSIFPRSWLT 213
17 PHA02533
large terminase protein; Provisional
6-221 1.40e-22

large terminase protein; Provisional


Pssm-ID: 222858 [Multi-domain]  Cd Length: 534  Bit Score: 100.12  E-value: 1.40e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   6 LYDYEKLWLKD--KNRFKIGMFARQTGKTFTTT---LEVVdsCFASQamgrkKRWVILSRGERQAKEAMDEgiklhskaY 80
Cdd:PHA02533  60 MRDYQKDMLKImhKNRFNACNLSRQLGKTTVVAiflLHYV--CFNKD-----KNVGILAHKASMAAEVLDR--------T 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  81 SLTIESL-DYEWEGTEGSHKAlEVSFSNGSKITALPANPDTARGFSASVL-LDEFAFHKDSRKIWTALFPVISAGHDLRV 158
Cdd:PHA02533 125 KQAIELLpDFLQPGIVEWNKG-SIELENGSKIGAYASSPDAVRGNSFAMIyIDECAFIPNFIDFWLAIQPVISSGRSSKI 203
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515516534 159 V--STPNGKgNKFYDLVTAEDP----------IWSKHIVDIYQAVEQGLPRDIEELRRALNDEDAWAQEYELKWL 221
Cdd:PHA02533 204 IitSTPNGL-NHFYDIWTAAVEgksgfvpytvHWSSVPERLYNDGIFDDDEEWKSQTIANSSLAQFRQEHECEFL 277
 
Name Accession Description Interval E-value
COG4373 COG4373
Mu-like prophage FluMu protein gp28 [Mobilome: prophages, transposons];
6-430 9.22e-54

Mu-like prophage FluMu protein gp28 [Mobilome: prophages, transposons];


Pssm-ID: 443501 [Multi-domain]  Cd Length: 512  Bit Score: 187.03  E-value: 9.22e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   6 LYDYEKLWLKDKNRFKIGMFARQTGKTFTTTLE-VVDSCFASQAMGRKKrWVIlSRGERQAKE-----AMdegiklHSKA 79
Cdd:COG4373   27 LLPYQQRWIADESPLKIAEKSRRTGLTWAEAADdVLTAAAARSAGGMNV-FYI-GYNKDMAREfidacAM------WAKA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  80 YSL---TIESLDYEWEGTEGSHKALEVSFSNGSKITALPANPDTARGFSASVLLDEFAFHKDSRKIWTALFPVISAGHDL 156
Cdd:COG4373   99 FNLaasEIEEFVFEDQGEDKDILAFRIRFASGFRIQALSSNPSNLRGKQGNVVIDEAAFHEDLAELLKAALALLMWGGKV 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 157 RVVSTPNGKGNKFYDLVT---AEDPIWSKHIVDIYQAVEQGLPRdieelRRALNDEDAWAQEYELKWLDE---------- 223
Cdd:COG4373  179 RIISTHNGVDNPFNELIRdirAGKKDYSVHRITFDDAVADGLYE-----RICLVTGKPWSPEAEAAWRADiradygddad 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 224 ----------ASAWLSYDLINA------------VEDDYAGIPDLY---------------------TGGPCFIGNDIGL 260
Cdd:COG4373  254 eeldcipkdgGGAYLPRALIEAcmsadipvlrweGPDDFNLRPELEreaemadwceehleplldaldPGLRHALGEDFAR 333
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 261 RRDLWVAWVWE-KVGDVFWCREVQTLKRSTFAEHDDCLDELMKK-YKVVRLCMDQSGMGEKPVQDAQRRYGMLRTEGVLF 338
Cdd:COG4373  334 SGDLSVIWPLEiQQDLRRRVPFLVELRNVPFDQQEQILFYILDRlPRFAGGALDATGNGQYLAEAAAQRYGAERVEEVML 413
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 339 TNTNKLVLATIGKQKFEDRKVRIPMgDSNLRSDLHSLKKLptptGGV-RFDADATE-----NGHADRAWAAFLGLYAGAN 412
Cdd:COG4373  414 SEAWYRENMPPFKAAFEDGTLTIPK-DEDVLDDLRAVQLV----RGVpRVPDGRTKgadggKRHGDSAIALALAYYASRQ 488
                        490
                 ....*....|....*...
gi 515516534 413 PGSPIEFQALGQKRLGFG 430
Cdd:COG4373  489 DGGPIEYASVPRRRAAAR 506
Terminase_6N pfam03237
Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal ...
24-234 9.31e-26

Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal domain of terminase large subunits found in a variety of the Caudovirales and prophage regions of bacterial genomes. It includes the terminase large subunit of Bacteriophage T4 (terminase gene 17, Gp17). homologs are also found in Gene Transfer Agents (GTA), including ORFg2 (RCAP_rcc01683) of the GTA of Rhodobacter capsulatus (Rhodopseudomonas capsulata).


Pssm-ID: 427210 [Multi-domain]  Cd Length: 214  Bit Score: 104.04  E-value: 9.31e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   24 MFARQTGKTFTTTLEvvdscFASQAMGRK-KRWVILSRGERQAKEAMDEGiklHSKAYSLTIESLDYEWEGtegsHKALE 102
Cdd:pfam03237   2 LGGRQSGKTFAGARE-----LLRHALGRGpENQIILSASKGQAREEGGEF---PKGIIELARDLLDPDFEE----SNKGS 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  103 VSFSNGSKITALPANPDTARGF----SASVLLDEFAFHKDSRKIWTALFPVISAGHD-LRVVSTPNGKGNKFYDLVT--- 174
Cdd:pfam03237  70 IVLSNGASLHFLSLNASTAGGYrgaqIDAIYFDEFAWIPKFQESWKVTRLRATLGTDtKTFITTPPTPLHGVYDFWTgwl 149
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515516534  175 ------AEDPIWSKHIVDIYQAVEQGLPRdIEELrRALNDEDAWAQEYELKWLDEASAWLSYDLIN 234
Cdd:pfam03237 150 eekgppSYVKIPATVEATIEDAVKLGEDL-IEEL-EALYSPDEFAQLLLGEFIDTSGSIFPRSWLT 213
17 PHA02533
large terminase protein; Provisional
6-221 1.40e-22

large terminase protein; Provisional


Pssm-ID: 222858 [Multi-domain]  Cd Length: 534  Bit Score: 100.12  E-value: 1.40e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   6 LYDYEKLWLKD--KNRFKIGMFARQTGKTFTTT---LEVVdsCFASQamgrkKRWVILSRGERQAKEAMDEgiklhskaY 80
Cdd:PHA02533  60 MRDYQKDMLKImhKNRFNACNLSRQLGKTTVVAiflLHYV--CFNKD-----KNVGILAHKASMAAEVLDR--------T 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  81 SLTIESL-DYEWEGTEGSHKAlEVSFSNGSKITALPANPDTARGFSASVL-LDEFAFHKDSRKIWTALFPVISAGHDLRV 158
Cdd:PHA02533 125 KQAIELLpDFLQPGIVEWNKG-SIELENGSKIGAYASSPDAVRGNSFAMIyIDECAFIPNFIDFWLAIQPVISSGRSSKI 203
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515516534 159 V--STPNGKgNKFYDLVTAEDP----------IWSKHIVDIYQAVEQGLPRDIEELRRALNDEDAWAQEYELKWL 221
Cdd:PHA02533 204 IitSTPNGL-NHFYDIWTAAVEgksgfvpytvHWSSVPERLYNDGIFDDDEEWKSQTIANSSLAQFRQEHECEFL 277
Terminase_6C pfam17289
Terminase RNaseH-like domain;
263-407 1.57e-13

Terminase RNaseH-like domain;


Pssm-ID: 435843 [Multi-domain]  Cd Length: 154  Bit Score: 67.80  E-value: 1.57e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  263 DLWVAWVWEKVGDVFWCREVQTLKRSTFAEHDDCLDELMKKYKVVRLCMDQSGMGEKPVQDAQRRYGmlRTEGVLFTNTN 342
Cdd:pfam17289  12 DYAAIVVIDVDGDKFYLLAREQERGNSPALQAAAIKKLAERYNVIYIYIDGTGGGESVAELLKRAFP--SAFAVRPEPAT 89
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515516534  343 --KLVLATIGKQKFEDRKVRIPMGDSNlRSDLHSLKKLPTPTGGVRfdadATENGHADRAWAAFLGL 407
Cdd:pfam17289  90 kgKTARVLKVNDLIESGRLKVDKGPDC-ANSFNALEKYHTDSGMER----SISTTHDDLADALRYAL 151
P PHA02535
terminase ATPase subunit; Provisional
6-402 9.79e-09

terminase ATPase subunit; Provisional


Pssm-ID: 222859 [Multi-domain]  Cd Length: 581  Bit Score: 57.39  E-value: 9.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534   6 LYDYEKLWLKDKN--RFKIGMFARQTGKTFTttlevvdscFASQAM------GRKKrwVILSRGERQAkEAMDEGIKLHS 77
Cdd:PHA02535 139 LFDYQKHWYRAGLhhRTRNILKSRQIGATYY---------FAREALedalltGRNQ--IFLSASKAQA-HVFKQYIIAFA 206
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534  78 KAYsltiesLDYEWEGTEgshkaleVSFSNGSKITALPANPDTARGFSASVLLDEFAfhkdsrkiWTALFPVIS------ 151
Cdd:PHA02535 207 REA------ADVELTGDP-------IILPNGAELHFLGTNANTAQSYHGNVYFDEYF--------WIPKFQELNkvasgm 265
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 152 AGHD-LRVV--STPNGKGNKFYDLVTAE----------------------------DPIWsKHIVDIYQAVEQGLPR-DI 199
Cdd:PHA02535 266 ATHKhWRKTyfSTPSSKTHEAYPFWSGElfnrgrpkrerieidtshealdggrlcpDGQW-RQIVTIEDALKGGCDLfDI 344
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 200 EELRRAlNDEDAWAQEYELKWLDEASAWLSYDL-------INAVEDDYA-GIPDLYTGGPCFIGNDIGLRRD---LWVAW 268
Cdd:PHA02535 345 EELRRE-YSAEDFANLFMCVFIDDAASVFPFSDlqrcmvdSWEEWEDYKpFAARPFGSREVWVGYDPAHTGDsagLVVVA 423
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515516534 269 VWEKVGDVFWCREVQTLKRSTFAEHDDCLDELMKKYKVVRLCMDQSGMGEKPVQDAQRRYGmlRTEGVLFTNTNKLVLAT 348
Cdd:PHA02535 424 PPAVPGGKFRVLERHQWRGLDFAEQAAEIRKLTEKYNVTYIGIDATGIGAGVYQLVKKFFP--AAVAINYSPEVKTRLVL 501
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 515516534 349 IGKQKFEDRKVRIPMGDSNLRSDLHSLKKLPTPTGG-VRFDADATEN-GHADRAWA 402
Cdd:PHA02535 502 KAHDVIEHGRLEFDAGWTDIAASFMAIKKTSTASGRqMTYTAERSEEtGHADLAWA 557
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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