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Conserved domains on  [gi|515616690|ref|WP_017049290|]
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type VI secretion system ImpA family N-terminal domain-containing protein [Vibrio anguillarum]

Protein Classification

type VI secretion system ImpA family N-terminal domain-containing protein( domain architecture ID 10536173)

type VI secretion system ImpA family N-terminal domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ImpA_N pfam06812
ImpA, N-terminal, type VI secretion system; This family represents a conserved region located ...
 26-117 1.71e-08

ImpA, N-terminal, type VI secretion system; This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. The ImpA gene in Vibrio cholera and many other bacteria is expressed from the virulence factor operon which produces the pathogenic injection, type VI secretion system; although the exact function of this gene-product is not known it appears to be an essential component of the pathogenic effect.


:

Pssm-ID: 429132 [Multi-domain]  Cd Length: 115  Bit Score: 52.24  E-value: 1.71e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515616690   26 AYQKVRDEINRRNNPLSGGPDWAVVKVACETLAKGPGIDLLLCGYYTVACLKMQGLAGYANGVELLCCCLSNL-----PK 100
Cdd:pfam06812  18 EFDALEEARNKADELAAKAVDWAKVERLALELLETRSKDLRVAAWLTEALIRLEGLAGLAEGLELLAGLLERYwdtlhPA 97

                          90
                  ....*....|....*..
gi 515616690  101 PDVKSAKMRKEVLDWVN 117
Cdd:pfam06812  98 LDDDDLEARVNALAWLN 114
 
Name Accession Description Interval E-value
ImpA_N pfam06812
ImpA, N-terminal, type VI secretion system; This family represents a conserved region located ...
 26-117 1.71e-08

ImpA, N-terminal, type VI secretion system; This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. The ImpA gene in Vibrio cholera and many other bacteria is expressed from the virulence factor operon which produces the pathogenic injection, type VI secretion system; although the exact function of this gene-product is not known it appears to be an essential component of the pathogenic effect.


Pssm-ID: 429132 [Multi-domain]  Cd Length: 115  Bit Score: 52.24  E-value: 1.71e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515616690   26 AYQKVRDEINRRNNPLSGGPDWAVVKVACETLAKGPGIDLLLCGYYTVACLKMQGLAGYANGVELLCCCLSNL-----PK 100
Cdd:pfam06812  18 EFDALEEARNKADELAAKAVDWAKVERLALELLETRSKDLRVAAWLTEALIRLEGLAGLAEGLELLAGLLERYwdtlhPA 97

                          90
                  ....*....|....*..
gi 515616690  101 PDVKSAKMRKEVLDWVN 117
Cdd:pfam06812  98 LDDDDLEARVNALAWLN 114
TssA1 COG3515
Type VI protein secretion system component TssA1/VasJ/EvfE, contains ImpA_N domain ...
 21-184 1.25e-05

Type VI protein secretion system component TssA1/VasJ/EvfE, contains ImpA_N domain [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442737 [Multi-domain]  Cd Length: 342  Bit Score: 46.93  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515616690  21 VRHIDAYQKVRDEINRRNNPLSG-------GPDWAVVKVACETLAKGPGIDLLLCGYYTVACLKMQGLAGYANGVELLCC 93
Cdd:COG3515   20 LRYDPDFDALKEARRGDDEQQQGdwvielkPADWREVERLAEELLTTRSKDLRVAVWLAEALLRLDGLAGLADGLELLAG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515616690  94 CLSN-----LPKPDVKSAKMRKEVLDWVN-----ARVVRELKDLRPNH--------EALRDLYRCERFC-------ERMH 148
Cdd:COG3515  100 LLERfwddlHPQLDEDDPEERVNALAWLNdprllLAPLRLAPLTEGRGgelslrdyEQARDLERLPARAaaipptlERLE 179

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 515616690 149 AILELQQPDYLVDFEGVGFAIFEHIDRLETQYHSLL 184
Cdd:COG3515  180 AALADTSAAFLQALLAALEAALAALEALEAALDERL 215
 
Name Accession Description Interval E-value
ImpA_N pfam06812
ImpA, N-terminal, type VI secretion system; This family represents a conserved region located ...
 26-117 1.71e-08

ImpA, N-terminal, type VI secretion system; This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. The ImpA gene in Vibrio cholera and many other bacteria is expressed from the virulence factor operon which produces the pathogenic injection, type VI secretion system; although the exact function of this gene-product is not known it appears to be an essential component of the pathogenic effect.


Pssm-ID: 429132 [Multi-domain]  Cd Length: 115  Bit Score: 52.24  E-value: 1.71e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515616690   26 AYQKVRDEINRRNNPLSGGPDWAVVKVACETLAKGPGIDLLLCGYYTVACLKMQGLAGYANGVELLCCCLSNL-----PK 100
Cdd:pfam06812  18 EFDALEEARNKADELAAKAVDWAKVERLALELLETRSKDLRVAAWLTEALIRLEGLAGLAEGLELLAGLLERYwdtlhPA 97

                          90
                  ....*....|....*..
gi 515616690  101 PDVKSAKMRKEVLDWVN 117
Cdd:pfam06812  98 LDDDDLEARVNALAWLN 114
TssA1 COG3515
Type VI protein secretion system component TssA1/VasJ/EvfE, contains ImpA_N domain ...
 21-184 1.25e-05

Type VI protein secretion system component TssA1/VasJ/EvfE, contains ImpA_N domain [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442737 [Multi-domain]  Cd Length: 342  Bit Score: 46.93  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515616690  21 VRHIDAYQKVRDEINRRNNPLSG-------GPDWAVVKVACETLAKGPGIDLLLCGYYTVACLKMQGLAGYANGVELLCC 93
Cdd:COG3515   20 LRYDPDFDALKEARRGDDEQQQGdwvielkPADWREVERLAEELLTTRSKDLRVAVWLAEALLRLDGLAGLADGLELLAG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515616690  94 CLSN-----LPKPDVKSAKMRKEVLDWVN-----ARVVRELKDLRPNH--------EALRDLYRCERFC-------ERMH 148
Cdd:COG3515  100 LLERfwddlHPQLDEDDPEERVNALAWLNdprllLAPLRLAPLTEGRGgelslrdyEQARDLERLPARAaaipptlERLE 179

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 515616690 149 AILELQQPDYLVDFEGVGFAIFEHIDRLETQYHSLL 184
Cdd:COG3515  180 AALADTSAAFLQALLAALEAALAALEALEAALDERL 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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