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Conserved domains on  [gi|515627758|ref|WP_017060358|]
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MULTISPECIES: carbohydrate ABC transporter permease [unclassified Vibrio]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
3-353 1.09e-70

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 222.70  E-value: 1.09e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   3 SLRLRQQVYGWLLAGPFVLTLVVFFLYALVRTVYFSFTEYDLFS-DAVWVGLANFKALLSDDLFLLSLANTIWFSLIVTC 81
Cdd:COG1175   11 RRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGpPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVP 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  82 VQTVLALGLAILVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFYQKN-GYLNGFVTDVvnhyphiscfvliavasqfv 160
Cdd:COG1175   91 LQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGAL-------------------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 161 lvtkdrikGL-PVGWF-DPAWAILSVIVAGIatfiasamgWIevtkdvvevnwlntrdhvgpmpltlwaiviqniytTIP 238
Cdd:COG1175  151 --------GLePINWLgDPSLALPAVIIVTV---------WK-----------------------------------GTG 178

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 239 TFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALLGSAAPLESRITMAYY 318
Cdd:COG1175  179 FNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLY 258

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 515627758 319 VYHNAFppgGTPQIGMASAAALILAFITLAVVYLQ 353
Cdd:COG1175  259 IYQTAF---QQFDFGYASAIAVVLFLIILVLTLLQ 290
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
3-353 1.09e-70

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 222.70  E-value: 1.09e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   3 SLRLRQQVYGWLLAGPFVLTLVVFFLYALVRTVYFSFTEYDLFS-DAVWVGLANFKALLSDDLFLLSLANTIWFSLIVTC 81
Cdd:COG1175   11 RRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGpPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVP 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  82 VQTVLALGLAILVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFYQKN-GYLNGFVTDVvnhyphiscfvliavasqfv 160
Cdd:COG1175   91 LQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGAL-------------------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 161 lvtkdrikGL-PVGWF-DPAWAILSVIVAGIatfiasamgWIevtkdvvevnwlntrdhvgpmpltlwaiviqniytTIP 238
Cdd:COG1175  151 --------GLePINWLgDPSLALPAVIIVTV---------WK-----------------------------------GTG 178

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 239 TFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALLGSAAPLESRITMAYY 318
Cdd:COG1175  179 FNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLY 258

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 515627758 319 VYHNAFppgGTPQIGMASAAALILAFITLAVVYLQ 353
Cdd:COG1175  259 IYQTAF---QQFDFGYASAIAVVLFLIILVLTLLQ 290
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
14-350 6.89e-09

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 56.37  E-value: 6.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  14 LLAGPFVLTLVVFFLYALVRTVYFSFTEYDLFS-DAVWVGLANFKALLSDDLFLLSLANTIWFSLIVTCVQTVLALGLAI 92
Cdd:PRK10561   1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGfSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  93 LVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFyqkngylngfvtdvvnhyphiscfvliavasqfvlvtkdrikglpv 172
Cdd:PRK10561  81 LVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFL---------------------------------------------- 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 173 gwFDPAwailsvivAGIATFIASAMGWievtkdvvevNWlntrDHVGPMPLTLWAIVIQNIYTTIPTFMLLFLAGLQGIS 252
Cdd:PRK10561 115 --FNPG--------RGLITHFLAEFGY----------DW----NHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIP 170

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 253 GELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIgtLQMFDQVALLGSA---APLESRITMAYYVYHNAFpPGGT 329
Cdd:PRK10561 171 RSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLV--YAFFDTFPVIDAAtsgGPVQATTTLIYKIYREGF-TGLD 247

                        330       340
                 ....*....|....*....|.
gi 515627758 330 PQIGMASAAALILAFITLAVV 350
Cdd:PRK10561 248 LSSSAAQSVVLMFLVIVLTVV 268
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 224-356 2.51e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.07  E-value: 2.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  224 TLWAIVIQNIYTTIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALL 303
Cdd:pfam00528  51 GILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL 130

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 515627758  304 GSAAPLESRITMAYYVYHNAFppggtpQIGMASAAALILAFITLAVVYLQKIF 356
Cdd:pfam00528 131 GSWPGLGLLLIEAILGYDYPE------IQGPVLAAALILLLLNLLVDILQRLL 177
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 223-347 8.02e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 46.12  E-value: 8.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 223 LTLWAIVIQNIYTtIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVAL 302
Cdd:cd06261   72 LGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF 150

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 515627758 303 LGSAAPLesRITMAYYVYHNAFPPGgtpQIGMASAAALILAFITL 347
Cdd:cd06261  151 LGGGEAP--GPGTGLLLIFAILFPG---DLGVAAAVALILLLLSL 190
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 13-290 1.17e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 46.98  E-value: 1.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   13 WLLAGPFVLTLVVFFLYALVRTVYFSFteydLFSDAVWVGLANFKALLSDDLFLLSLANTIWFSLIVTCVQTVLALGLAI 92
Cdd:TIGR03262   4 RLLLAGMILALLLFLLLPLLALLTKSV----YDSDGDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   93 -LVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFYQKNGYLNGFVTDvvnhyphiscfvliavasqfvlvtkdrikglp 171
Cdd:TIGR03262  80 aLTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGG-------------------------------- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  172 vgwfdpawailsvivagiatfiASAMGwievtkdvvevnwlntrdhvgpmpltLWAIVIQNIYTTIPTFMLLFLAGLQGI 251
Cdd:TIGR03262 128 ----------------------FSIYG--------------------------FWGIVIGEVFYTFPHALMILVTALSLA 159

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 515627758  252 SGELYEAAHIDGANKWQQHWNITIPQ----LAPVTFVVVTFSI 290
Cdd:TIGR03262 160 DGRLYEAARAMGASPWRTFFTVTLPGakygLISAAFVVFTLVI 202
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
3-353 1.09e-70

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 222.70  E-value: 1.09e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   3 SLRLRQQVYGWLLAGPFVLTLVVFFLYALVRTVYFSFTEYDLFS-DAVWVGLANFKALLSDDLFLLSLANTIWFSLIVTC 81
Cdd:COG1175   11 RRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGpPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVP 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  82 VQTVLALGLAILVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFYQKN-GYLNGFVTDVvnhyphiscfvliavasqfv 160
Cdd:COG1175   91 LQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGAL-------------------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 161 lvtkdrikGL-PVGWF-DPAWAILSVIVAGIatfiasamgWIevtkdvvevnwlntrdhvgpmpltlwaiviqniytTIP 238
Cdd:COG1175  151 --------GLePINWLgDPSLALPAVIIVTV---------WK-----------------------------------GTG 178

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 239 TFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALLGSAAPLESRITMAYY 318
Cdd:COG1175  179 FNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGGGPGNSTTTLVLY 258

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 515627758 319 VYHNAFppgGTPQIGMASAAALILAFITLAVVYLQ 353
Cdd:COG1175  259 IYQTAF---QQFDFGYASAIAVVLFLIILVLTLLQ 290
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 5-352 1.83e-20

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 90.53  E-value: 1.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   5 RLRQQVYGWLLAGPFVLTLVVFF---LYALVrtvyFSFTEYDL---FSDAVWVGLANFKALLSDDLFLLSLANTIWFSLI 78
Cdd:COG4209   22 RLKRDWQLYLMLLPGLIYLLIFSylpMYGIV----IAFKDYNPfkgIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISLL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  79 VTCVQTVLALGLAILVNS--KIRAKSFFRTAFYLPSILSSAAV-TLIFIWFYQKNGYLNGFVTDVvnhyphiscfvliav 155
Cdd:COG4209   98 KLVFGFPLPIILALLLNElrSKRFKKTVQTISYLPHFLSWVVVaGIVYQFLSPDTGLVNQLLRAL--------------- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 156 asqfvlvtkdrikglpvgwfdpawailsvivaGIATfiasamgwievtkdvveVNWLNTRDHVGPMpltlwaIVIQNI-- 233
Cdd:COG4209  163 --------------------------------GGEP-----------------INFLTEPKYFRPI------YVFSGIwk 187

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 234 ---YTTIptfmlLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQM-FDQVALLGSAAPL 309
Cdd:COG4209  188 eagWGSI-----IYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVILLILNIGNILNVgFEQIYLLYNPLNY 262

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 515627758 310 ESRITMAYYVYHNAFppgGTPQIGMASAAALILAFITLAVVYL 352
Cdd:COG4209  263 STSDVIDTYVYRIGL---QNGDYSYATAVGLFKSVVGLILVLI 302
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 3-364 6.70e-20

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 88.28  E-value: 6.70e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   3 SLRLRQQVYGWLLAGPFVLTLVVFFLYALVRTVYFSFTEYDLFSDAVWV-GLANFKALLSDDLFLLSLANTIWFSLIVTC 81
Cdd:COG1176    2 SAALRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGfTLENYARLFTDPLYLKVLLRTLWIALLTTL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  82 VQTVLALGLA-ILVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFYQKNGYLNGFVtdvvnhyphiscfvliavasqfv 160
Cdd:COG1176   82 ICLLLGYPIAyFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLL----------------------- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 161 lvtkdrikglpvgwfdpawailsvivagiatfiaSAMGWIEvtkdvvevnwlntrdhvGPMPL--TLWAIVIQNIYTTIP 238
Cdd:COG1176  139 ----------------------------------LALGLID-----------------EPLRLlyTEFAVVIGLVYVYLP 167

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 239 TFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALLGSAAPLesriTMAYY 318
Cdd:COG1176  168 FMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVL----MIGNL 243

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 515627758 319 VYHNAFppgGTPQIGMASAAALILAFITLAVVYL-QKIFGIKEKADG 364
Cdd:COG1176  244 IYQQFL---SALNWPLAAALAVVLLLIVLLVLLLyLRLLRRRRLLGG 287
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
1-356 1.93e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 74.43  E-value: 1.93e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   1 MNSLRLRQQVYGWLLAgpfVLTLVVFFLYALVRtvyfsfteydLFSDAVWVGLANFKALLSDDLFLLSLANTIWFSLIVT 80
Cdd:COG1178    1 MSTRPRRRPRLLLLLL---ALLLALLVLLPLLA----------LLLRAFTDGLANFWALLSDPYLWRALGNTLLLALLVT 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  81 CVQTVLALGLAILVN-SKIRAKSFFRTAFYLPSILSSAAVTLIFIWFYQKNGYLNgfvtdvvnhyphiscfvliavasqf 159
Cdd:COG1178   68 LLSLLLGVPLAWLLArTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLN------------------------- 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 160 vlvtkdrikglpvgwfdpawailsvivagiaTFIASAMGWIEvtkdvvevnwlntrdhvgPMPLTLWAIVIQNIYTTIPT 239
Cdd:COG1178  123 -------------------------------TLLRALFGLEP------------------PDIYGLGGIILVLVLFNYPY 153

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 240 FMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALLGSAAPlesriTMAYYV 319
Cdd:COG1178  154 VYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLGGGYT-----TLTTAI 228

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 515627758 320 YHNAFppgGTPQIGMASAAALILAFITLAVVYLQKIF 356
Cdd:COG1178  229 YQAWL---GDFDLGAAAALALVLLLLVLLLLLLERRL 262
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
14-350 6.89e-09

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 56.37  E-value: 6.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  14 LLAGPFVLTLVVFFLYALVRTVYFSFTEYDLFS-DAVWVGLANFKALLSDDLFLLSLANTIWFSLIVTCVQTVLALGLAI 92
Cdd:PRK10561   1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGfSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  93 LVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFyqkngylngfvtdvvnhyphiscfvliavasqfvlvtkdrikglpv 172
Cdd:PRK10561  81 LVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFL---------------------------------------------- 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 173 gwFDPAwailsvivAGIATFIASAMGWievtkdvvevNWlntrDHVGPMPLTLWAIVIQNIYTTIPTFMLLFLAGLQGIS 252
Cdd:PRK10561 115 --FNPG--------RGLITHFLAEFGY----------DW----NHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIP 170

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 253 GELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIgtLQMFDQVALLGSA---APLESRITMAYYVYHNAFpPGGT 329
Cdd:PRK10561 171 RSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLV--YAFFDTFPVIDAAtsgGPVQATTTLIYKIYREGF-TGLD 247

                        330       340
                 ....*....|....*....|.
gi 515627758 330 PQIGMASAAALILAFITLAVV 350
Cdd:PRK10561 248 LSSSAAQSVVLMFLVIVLTVV 268
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 224-356 2.51e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.07  E-value: 2.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  224 TLWAIVIQNIYTTIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALL 303
Cdd:pfam00528  51 GILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL 130

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 515627758  304 GSAAPLESRITMAYYVYHNAFppggtpQIGMASAAALILAFITLAVVYLQKIF 356
Cdd:pfam00528 131 GSWPGLGLLLIEAILGYDYPE------IQGPVLAAALILLLLNLLVDILQRLL 177
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 224-293 2.02e-07

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 51.63  E-value: 2.02e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 224 TLWAIVIQNIYTTIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGT 293
Cdd:COG0395  143 TYWGLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGA 212
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
224-352 7.01e-07

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 50.93  E-value: 7.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 224 TLWAIVIQNIYTTIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVALL 303
Cdd:COG1178  410 TLAILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLL 489

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 515627758 304 GSAapleSRITMAYYVYHNAfppgGTPQIGMASAAALILAFITLAVVYL 352
Cdd:COG1178  490 RPP----GFETLAVLIYQLA----SSGRYGEAAALALLLVLVSLLPVLL 530
malF PRK10999
maltose ABC transporter permease MalF;
228-352 1.29e-06

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 49.96  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 228 IVIQNIYTTIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQL-APVT-------------FVVVTFSIIGT 293
Cdd:PRK10999 378 ILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLiKPLTplmiasfafnfnnFVLIQLLTNGG 457

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515627758 294 LQMfdqvalLGSAAPLESRITMAYYVYHNAFPPGGTPQIGMASAAALILAFI--TLAVVYL 352
Cdd:PRK10999 458 PDM------IGTTTPAGYTDLLVSYTYRIAFEGGGGQDFGLAAAIATLIFLLvgALAILNL 512
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 223-347 8.02e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 46.12  E-value: 8.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 223 LTLWAIVIQNIYTtIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQVAL 302
Cdd:cd06261   72 LGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSF 150

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 515627758 303 LGSAAPLesRITMAYYVYHNAFPPGgtpQIGMASAAALILAFITL 347
Cdd:cd06261  151 LGGGEAP--GPGTGLLLIFAILFPG---DLGVAAAVALILLLLSL 190
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 13-290 1.17e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 46.98  E-value: 1.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   13 WLLAGPFVLTLVVFFLYALVRTVYFSFteydLFSDAVWVGLANFKALLSDDLFLLSLANTIWFSLIVTCVQTVLALGLAI 92
Cdd:TIGR03262   4 RLLLAGMILALLLFLLLPLLALLTKSV----YDSDGDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758   93 -LVNSKIRAKSFFRTAFYLPSILSSAAVTLIFIWFYQKNGYLNGFVTDvvnhyphiscfvliavasqfvlvtkdrikglp 171
Cdd:TIGR03262  80 aLTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGG-------------------------------- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758  172 vgwfdpawailsvivagiatfiASAMGwievtkdvvevnwlntrdhvgpmpltLWAIVIQNIYTTIPTFMLLFLAGLQGI 251
Cdd:TIGR03262 128 ----------------------FSIYG--------------------------FWGIVIGEVFYTFPHALMILVTALSLA 159

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 515627758  252 SGELYEAAHIDGANKWQQHWNITIPQ----LAPVTFVVVTFSI 290
Cdd:TIGR03262 160 DGRLYEAARAMGASPWRTFFTVTLPGakygLISAAFVVFTLVI 202
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 220-352 3.92e-04

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 41.64  E-value: 3.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 220 PMPLTLWAIVIQNIYTTIPTFMLLFLAGLQGISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGTLQMFDQ 299
Cdd:COG1177  126 GLSGGLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVI 205

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 515627758 300 VALLGSAapleSRITMAYYVYhNAFPPGGTPQIgmaSAAALILAFITLAVVYL 352
Cdd:COG1177  206 TLFLAGP----GVTTLPVYIY-SMIRRGISPEI---NALSTLLILLSLLLLLL 250
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 185-352 1.20e-03

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 40.12  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 185 IVAGIA-TFIASAMGWIEVTKDVVEVNWLNTRdhvgpmpltlWAIVIQNIYTTIPTFMLLFLAGLQGISGELYEAAHIDG 263
Cdd:COG0555  105 AVAGIAlLLLFGPNGWLGQLLAPLGIKVAFTP----------LGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLG 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515627758 264 ANKWQQHWNITIPQLAP--VTFVVVTFS-----------IIGTLQMFDQVallgsaAPLESRITMAYYVYHNAfppggtp 330
Cdd:COG0555  175 ASRWQTFRRVILPLLLPalLTGFALAFAralgefgavifIAGNLPMKTEI------LPLLIYLKLEEGDYAGA------- 241

                        170       180
                 ....*....|....*....|...
gi 515627758 331 qigMASAAALIL-AFITLAVVYL 352
Cdd:COG0555  242 ---TAIALVLLLiSFLLLLLINL 261
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 251-293 4.22e-03

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 38.59  E-value: 4.22e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 515627758 251 ISGELYEAAHIDGANKWQQHWNITIPQLAPVTFVVVTFSIIGT 293
Cdd:COG3833  169 IPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGP 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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