NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|515628464|ref|WP_017061064|]
View 

MULTISPECIES: TAXI family TRAP transporter solute-binding subunit [Vibrio]

Protein Classification

TAXI family TRAP transporter solute-binding subunit( domain architecture ID 11245793)

TAXI family TRAP transporter solute-binding subunit is a component of an ATP-independent periplasmic transporter and belongs to type 2 periplasmic-binding fold protein (PBP2) superfamily; the substrate spectrum of TAXI proteins remains to be defined

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
NMT1_3 pfam16868
NMT1-like family;
33-327 8.35e-129

NMT1-like family;


:

Pssm-ID: 435616 [Multi-domain]  Cd Length: 289  Bit Score: 369.66  E-value: 8.35e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464   33 LATASTGGTYYPVGVALATLSKVKLAPKQHFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKSGRQT 112
Cdd:pfam16868   1 IGTGSTGGTYYPVGVAIATLISNKLGKDQGVQCSVQSTGGSVENIQLLRNGEADLAILQSDFAYEAYEGTGPFAGKGPLK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  113 QLRSVSMLWQNVEHFIVRsdlaKTGTVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNPEQF-KLAFMGYGGSASAL 191
Cdd:pfam16868  81 NLRAITMLYPEPFQFVVS----KDSGIGSIADLKGKRVSVGPPGSGTEGSTRAILGALGISYKDLsLLEYLGYGESADAL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  192 QNGTIDGMNTPAGVPVGAVTQAFAalGEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGvDKPITTIAQPNFLAVRE 271
Cdd:pfam16868 157 KDGQLDGAFFPAGPPVSAVTQLAA--SVDINLIGLDDEQLDKLLAEYPYWTPYIIPAGTYPQ-DEDVPTIAVPNFLVTRA 233
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 515628464  272 DISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYYREMG 327
Cdd:pfam16868 234 DLDEELVYLLTKAIFENLDFLNQIHAAAKEISLEKALAGLPVPLHPGAERYYKEQG 289
 
Name Accession Description Interval E-value
NMT1_3 pfam16868
NMT1-like family;
33-327 8.35e-129

NMT1-like family;


Pssm-ID: 435616 [Multi-domain]  Cd Length: 289  Bit Score: 369.66  E-value: 8.35e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464   33 LATASTGGTYYPVGVALATLSKVKLAPKQHFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKSGRQT 112
Cdd:pfam16868   1 IGTGSTGGTYYPVGVAIATLISNKLGKDQGVQCSVQSTGGSVENIQLLRNGEADLAILQSDFAYEAYEGTGPFAGKGPLK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  113 QLRSVSMLWQNVEHFIVRsdlaKTGTVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNPEQF-KLAFMGYGGSASAL 191
Cdd:pfam16868  81 NLRAITMLYPEPFQFVVS----KDSGIGSIADLKGKRVSVGPPGSGTEGSTRAILGALGISYKDLsLLEYLGYGESADAL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  192 QNGTIDGMNTPAGVPVGAVTQAFAalGEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGvDKPITTIAQPNFLAVRE 271
Cdd:pfam16868 157 KDGQLDGAFFPAGPPVSAVTQLAA--SVDINLIGLDDEQLDKLLAEYPYWTPYIIPAGTYPQ-DEDVPTIAVPNFLVTRA 233
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 515628464  272 DISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYYREMG 327
Cdd:pfam16868 234 DLDEELVYLLTKAIFENLDFLNQIHAAAKEISLEKALAGLPVPLHPGAERYYKEQG 289
TRAP_TAXI TIGR02122
TRAP transporter solute receptor, TAXI family; This family is one of at least three major ...
4-327 1.37e-114

TRAP transporter solute receptor, TAXI family; This family is one of at least three major families of extracytoplasmic solute receptor (ESR) for TRAP (Tripartite ATP-independent Periplasmic Transporter) transporters. The others are the DctP (TIGR00787) and SmoM (pfam03480) families. These transporters are secondary (driven by an ion gradient) but composed of three polypeptides, although in some species the 4-TM and 12-TM integral membrane proteins are fused. Substrates for this transporter family are not fully characterized but, besides C4 dicarboxylates, may include mannitol and other compounds. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273982 [Multi-domain]  Cd Length: 320  Bit Score: 334.68  E-value: 1.37e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464    4 NKLVKTLALAMASLGLISNASAE---EDRSYILATASTGGTYYPVGVALATLSKVKLAPkqhFSLAAISSAGSGENVKLL 80
Cdd:TIGR02122   2 KKRLFLLGAALAIVGAALAACAGdggEPTFVTIGTGGTGGVYYPIGGAIAQLINKKSGK---LRVRVQSTGGSVENVNLL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464   81 NENEAQFAILQGLYGAWAWQGLGPYEKSGRQTQLRSVSMLWQNVEHFIVRSDlAKTGTVSDLEnlnGKKFSIGKKNSGTE 160
Cdd:TIGR02122  79 EAGEADLAIVQSDVAYYAYEGDGEFEFEGPVEKLRALASLYPEYIQIVVRKD-SGIKTVADLK---GKRVAVGAPGSGTE 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  161 NSGRQIMQGLSVNPEQFKLA-FMGYGGSASALQNGTIDGMNTPAGVPVGAVTQAFAALgeDIQILSFTDAQIKQANGDYN 239
Cdd:TIGR02122 155 LNARAVLKAAGLTYDDVKKVeYLGYAEAADALKDGKIDAAFYTAGTPTAAITELATSL--DIRIVPISGEKVEKLREKYP 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  240 IWTKYEIPANTYPGVDKPITTIAQPNFLAVREDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGA 319
Cdd:TIGR02122 233 FYRKGVIPAGTYPGQDEDVPTLAVPAALVTSSDVPEDLVYQITKAIFENLDELKDAHPAAQDIALETAIKGLPVPLHPGA 312

                  ....*...
gi 515628464  320 ARYYREMG 327
Cdd:TIGR02122 313 EKYYKEVG 320
Imp COG2358
TRAP-type uncharacterized transport system, periplasmic component [General function prediction ...
23-330 1.17e-109

TRAP-type uncharacterized transport system, periplasmic component [General function prediction only];


Pssm-ID: 441925 [Multi-domain]  Cd Length: 303  Bit Score: 321.41  E-value: 1.17e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  23 ASAEEDRSYILATASTGGTYYPVGVALATLSKVKLApkqHFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGL 102
Cdd:COG2358    6 AAAAAPQFLTIGTGGTGGTYYPIGGAIAKVVNKELP---GIRVTVQSTGGSVENLRLLRAGEADLAIVQSDVAYDAYNGT 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 103 GPYEKsGRQTQLRSVSMLWQNVEHFIVRSDlaktGTVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNPEQFKLAFM 182
Cdd:COG2358   83 GPFEG-GPLDNLRALASLYPEPVHLVVRAD----SGIKSLADLKGKRVSVGPPGSGTEVTAERLLEAAGLTYDDVKVEYL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 183 GYGGSASALQNGTIDGMNTPAGVPVGAVTQAFAAlgEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIA 262
Cdd:COG2358  158 GYGEAADALKDGQIDAAFFVAGLPTGAVTELAAT--TDIRLLPVDDEAIAKLLEKYPYYAPATIPAGTYPGQDEDVPTVA 235
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515628464 263 QPNFLAVREDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYYREMGIEI 330
Cdd:COG2358  236 VPAVLVTRADLPEDLVYELTKALFENLDELKAAHPAAKELTPETALDGLPVPLHPGAARYYKEKGLLK 303
PBP2_TAXI_TRAP cd13520
Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic ...
31-323 4.71e-104

Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold; This group includes Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family and closely related proteins. TRAP transporters are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an SBP (substrate-binding protein) of the DctP or TAXI families and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function. The substrate-binding domain of TAXI proteins belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and tworeceptor cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270238 [Multi-domain]  Cd Length: 285  Bit Score: 306.47  E-value: 4.71e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  31 YILATASTGGTYYPVGVALATLSKVKLAPkqhFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKsGR 110
Cdd:cd13520    2 LTIATGSTGGTYYPLGGALANLLNKKLPG---VRATAVSTGGSVENLRLLESGEADFGLAQSDVAYDAYNGTGPFEG-KP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 111 QTQLRSVSMLWQNVEHFIVRSDlAKTGTVSDLEnlnGKKFSIGKKNSGTENSGRQIMQGLSVNPEQFKLAFMGYGGSASA 190
Cdd:cd13520   78 IDNLRAVASLYPEYLHLVVRKD-SGIKSIADLK---GKRVAVGPPGSGTELTARRLLEAYGLTDDDVKAEYLGLSDAADA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 191 LQNGTIDGMNTPAGVPVGAVTQAFAAlgEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIAQPNFLAVR 270
Cdd:cd13520  154 LKDGQIDAFFWVGGLPASAITELAAT--RDIRLLPIDDEEIAKLLAEYPYYVPATIPAGTYPGQDEDVPTVAVPALLVTR 231
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 515628464 271 EDISEDDVYQLTKAIYENLPFLQGIHKATKA-MALEKGIAGLPVPLHPGAARYY 323
Cdd:cd13520  232 ADLPEDLVYQLTKALYENRDELAAAHPAAKQlISLETAIDGLPIPLHPGAERYY 285
 
Name Accession Description Interval E-value
NMT1_3 pfam16868
NMT1-like family;
33-327 8.35e-129

NMT1-like family;


Pssm-ID: 435616 [Multi-domain]  Cd Length: 289  Bit Score: 369.66  E-value: 8.35e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464   33 LATASTGGTYYPVGVALATLSKVKLAPKQHFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKSGRQT 112
Cdd:pfam16868   1 IGTGSTGGTYYPVGVAIATLISNKLGKDQGVQCSVQSTGGSVENIQLLRNGEADLAILQSDFAYEAYEGTGPFAGKGPLK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  113 QLRSVSMLWQNVEHFIVRsdlaKTGTVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNPEQF-KLAFMGYGGSASAL 191
Cdd:pfam16868  81 NLRAITMLYPEPFQFVVS----KDSGIGSIADLKGKRVSVGPPGSGTEGSTRAILGALGISYKDLsLLEYLGYGESADAL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  192 QNGTIDGMNTPAGVPVGAVTQAFAalGEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGvDKPITTIAQPNFLAVRE 271
Cdd:pfam16868 157 KDGQLDGAFFPAGPPVSAVTQLAA--SVDINLIGLDDEQLDKLLAEYPYWTPYIIPAGTYPQ-DEDVPTIAVPNFLVTRA 233
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 515628464  272 DISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYYREMG 327
Cdd:pfam16868 234 DLDEELVYLLTKAIFENLDFLNQIHAAAKEISLEKALAGLPVPLHPGAERYYKEQG 289
TRAP_TAXI TIGR02122
TRAP transporter solute receptor, TAXI family; This family is one of at least three major ...
4-327 1.37e-114

TRAP transporter solute receptor, TAXI family; This family is one of at least three major families of extracytoplasmic solute receptor (ESR) for TRAP (Tripartite ATP-independent Periplasmic Transporter) transporters. The others are the DctP (TIGR00787) and SmoM (pfam03480) families. These transporters are secondary (driven by an ion gradient) but composed of three polypeptides, although in some species the 4-TM and 12-TM integral membrane proteins are fused. Substrates for this transporter family are not fully characterized but, besides C4 dicarboxylates, may include mannitol and other compounds. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273982 [Multi-domain]  Cd Length: 320  Bit Score: 334.68  E-value: 1.37e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464    4 NKLVKTLALAMASLGLISNASAE---EDRSYILATASTGGTYYPVGVALATLSKVKLAPkqhFSLAAISSAGSGENVKLL 80
Cdd:TIGR02122   2 KKRLFLLGAALAIVGAALAACAGdggEPTFVTIGTGGTGGVYYPIGGAIAQLINKKSGK---LRVRVQSTGGSVENVNLL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464   81 NENEAQFAILQGLYGAWAWQGLGPYEKSGRQTQLRSVSMLWQNVEHFIVRSDlAKTGTVSDLEnlnGKKFSIGKKNSGTE 160
Cdd:TIGR02122  79 EAGEADLAIVQSDVAYYAYEGDGEFEFEGPVEKLRALASLYPEYIQIVVRKD-SGIKTVADLK---GKRVAVGAPGSGTE 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  161 NSGRQIMQGLSVNPEQFKLA-FMGYGGSASALQNGTIDGMNTPAGVPVGAVTQAFAALgeDIQILSFTDAQIKQANGDYN 239
Cdd:TIGR02122 155 LNARAVLKAAGLTYDDVKKVeYLGYAEAADALKDGKIDAAFYTAGTPTAAITELATSL--DIRIVPISGEKVEKLREKYP 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  240 IWTKYEIPANTYPGVDKPITTIAQPNFLAVREDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGA 319
Cdd:TIGR02122 233 FYRKGVIPAGTYPGQDEDVPTLAVPAALVTSSDVPEDLVYQITKAIFENLDELKDAHPAAQDIALETAIKGLPVPLHPGA 312

                  ....*...
gi 515628464  320 ARYYREMG 327
Cdd:TIGR02122 313 EKYYKEVG 320
Imp COG2358
TRAP-type uncharacterized transport system, periplasmic component [General function prediction ...
23-330 1.17e-109

TRAP-type uncharacterized transport system, periplasmic component [General function prediction only];


Pssm-ID: 441925 [Multi-domain]  Cd Length: 303  Bit Score: 321.41  E-value: 1.17e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  23 ASAEEDRSYILATASTGGTYYPVGVALATLSKVKLApkqHFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGL 102
Cdd:COG2358    6 AAAAAPQFLTIGTGGTGGTYYPIGGAIAKVVNKELP---GIRVTVQSTGGSVENLRLLRAGEADLAIVQSDVAYDAYNGT 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 103 GPYEKsGRQTQLRSVSMLWQNVEHFIVRSDlaktGTVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNPEQFKLAFM 182
Cdd:COG2358   83 GPFEG-GPLDNLRALASLYPEPVHLVVRAD----SGIKSLADLKGKRVSVGPPGSGTEVTAERLLEAAGLTYDDVKVEYL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 183 GYGGSASALQNGTIDGMNTPAGVPVGAVTQAFAAlgEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIA 262
Cdd:COG2358  158 GYGEAADALKDGQIDAAFFVAGLPTGAVTELAAT--TDIRLLPVDDEAIAKLLEKYPYYAPATIPAGTYPGQDEDVPTVA 235
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515628464 263 QPNFLAVREDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYYREMGIEI 330
Cdd:COG2358  236 VPAVLVTRADLPEDLVYELTKALFENLDELKAAHPAAKELTPETALDGLPVPLHPGAARYYKEKGLLK 303
PBP2_TAXI_TRAP cd13520
Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic ...
31-323 4.71e-104

Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold; This group includes Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family and closely related proteins. TRAP transporters are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an SBP (substrate-binding protein) of the DctP or TAXI families and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function. The substrate-binding domain of TAXI proteins belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and tworeceptor cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270238 [Multi-domain]  Cd Length: 285  Bit Score: 306.47  E-value: 4.71e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  31 YILATASTGGTYYPVGVALATLSKVKLAPkqhFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKsGR 110
Cdd:cd13520    2 LTIATGSTGGTYYPLGGALANLLNKKLPG---VRATAVSTGGSVENLRLLESGEADFGLAQSDVAYDAYNGTGPFEG-KP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 111 QTQLRSVSMLWQNVEHFIVRSDlAKTGTVSDLEnlnGKKFSIGKKNSGTENSGRQIMQGLSVNPEQFKLAFMGYGGSASA 190
Cdd:cd13520   78 IDNLRAVASLYPEYLHLVVRKD-SGIKSIADLK---GKRVAVGPPGSGTELTARRLLEAYGLTDDDVKAEYLGLSDAADA 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 191 LQNGTIDGMNTPAGVPVGAVTQAFAAlgEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIAQPNFLAVR 270
Cdd:cd13520  154 LKDGQIDAFFWVGGLPASAITELAAT--RDIRLLPIDDEEIAKLLAEYPYYVPATIPAGTYPGQDEDVPTVAVPALLVTR 231
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 515628464 271 EDISEDDVYQLTKAIYENLPFLQGIHKATKA-MALEKGIAGLPVPLHPGAARYY 323
Cdd:cd13520  232 ADLPEDLVYQLTKALYENRDELAAAHPAAKQlISLETAIDGLPIPLHPGAERYY 285
PBP2_TtGluBP cd13567
Substrate binding domain of Thermus thermophilus GluBP (TtGluBP) of TAXI family of the ...
30-323 1.47e-77

Substrate binding domain of Thermus thermophilus GluBP (TtGluBP) of TAXI family of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold; This subgroup includes TtGluBP of TAXI-TRAP family and closely related proteins. TRAP transporters are comprised of an SBP (substrate-binding protein) and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function.


Pssm-ID: 270285 [Multi-domain]  Cd Length: 284  Bit Score: 239.04  E-value: 1.47e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  30 SYILATASTGGTYYPVGVALATLSKvKLAPKQHFSlaAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKsG 109
Cdd:cd13567    1 FITIGTGGTSGTYYPLGGAIANIVN-KAIPGINAS--AQSTGASVANINLLGAGEAELALAQNDVAYYAYNGTGEFEG-K 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 110 RQTQLRSVSMLWQNVEHFIVRSDlakTG--TVSDLEnlnGKKFSIGKKNSGTENSGRQIMQGLSVNPEQFKLAFMGYGGS 187
Cdd:cd13567   77 PVKNLRALAALYPETVQIVVRAD---SGikTVADLK---GKRVSVGAPGSGTEVNARQILEAAGLTYDDIKVVYLSFAEA 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 188 ASALQNGTIDGMNTPAGVPVGAVTQAfaALGEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIAQPNFL 267
Cdd:cd13567  151 AEALKDGQIDAAFVTSGLPTAAIEEL--ATTVDIRIVPIDDEAIDKLKEKYPFYSKTTIPAGTYKGQDEDVETVAVQAML 228
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 515628464 268 AVREDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYY 323
Cdd:cd13567  229 VVSEDLSEDTVYDLTKALFEHLDELQASHAAAKQIDLETALEGMSIPLHPGAAKYY 284
PBP2_TAXI_TRAP_like_1 cd13569
Substrate binding domain of putative TAXI proteins of the tripartite ATP-independent ...
30-323 9.10e-61

Substrate binding domain of putative TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold; This subgroup includes uncharacterized periplasmic binding proteins that are related to Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family. TRAP transporters are comprised of an SBP (substrate-binding protein) and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function.


Pssm-ID: 270287 [Multi-domain]  Cd Length: 283  Bit Score: 195.95  E-value: 9.10e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  30 SYILATASTGGTYYPVGVALAT-LSKVklAPKQHFSlaAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKS 108
Cdd:cd13569    1 RLTIATGGTGGVYYPFGGGLAEiLSKA--VPDVRAT--AEVTGASVENLRLVASGEADLGFALADAALDAYNGEGPFSGP 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 109 GRqtqLRSVSMLWQNVEHFIVRSDlakTGtVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNPEQF-KLAFMGYGGS 187
Cdd:cd13569   77 VP---LRALARLYPNYLHLVVRAD---SG-ITSLEDLKGKRVSVGAPGSGTEVTAERLLEAAGLDPDKDvKRERLGLAES 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 188 ASALQNGTIDGMNTPAGVPVGAVTQAfaALGEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIAQPNFL 267
Cdd:cd13569  150 VAALKDGQIDAFFWSGGLPTSAITDL--ARTRDIRLVDLSDELVALREKYGPFYEAVTIPAGTYPGQVEDVPTLGVPNLL 227
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 515628464 268 AVREDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYY 323
Cdd:cd13569  228 VVRADLPDDLAYEITKTIFENLDDLVAAHPAAEQLDPRTAISTAPIPLHPGAARYY 283
PBP2_TAXI_TRAP_like_3 cd13568
Substrate binding domain of putative TAXI proteins of the tripartite ATP-independent ...
33-323 1.73e-53

Substrate binding domain of putative TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold; This subgroup includes uncharacterized periplasmic binding proteins that are related to Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family. TRAP transporters are comprised of an SBP (substrate-binding protein) and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function.


Pssm-ID: 270286 [Multi-domain]  Cd Length: 289  Bit Score: 177.50  E-value: 1.73e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  33 LATASTGGTYYPVGVALATLSKvKLAPKQHFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKSGRQT 112
Cdd:cd13568    4 IGTGSVTGVYYPIGGAICRLIN-KDRKSHGIRCSVESTGGSVANLNALREGEVDFALVQSDWAYHAYNGTGSFEAGGPMS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 113 QLRSVSMLwqNVEHF--IVRSDlaktGTVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNPEQFKLAF-MGYGGSAS 189
Cdd:cd13568   83 ELRAVFSL--HPEAFtvVARAD----SGIKSFDDLKGKRVNIGNPGSGQRATMLALLGAKGWTKKDFALAIeLKASEQAE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 190 ALQNGTIDGMNTPAGVPVGAVTQAfaALGEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIAQPNFLAV 269
Cdd:cd13568  157 ALCDGKIDAMVYVVGHPNGAIQEA--TTTCDAKLVPIDGETIDALVKDNPYYQKATIPGGLYPGNPEDVPTVGVKATLVT 234
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 515628464 270 REDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIA-GLPVPLHPGAARYY 323
Cdd:cd13568  235 TAEVSEDTVYKLVKAVFENFDEFKKLHPALANLLTVEMIKdGLSAPLHPGAIKYY 289
PBP2_TAXI_TRAP_like_2 cd13570
Substrate binding domain of putative TAXI proteins of the tripartite ATP-independent ...
30-323 4.31e-37

Substrate binding domain of putative TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold; This subgroup includes uncharacterized periplasmic binding proteins that are related to Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family. TRAP transporters are comprised of an SBP (substrate-binding protein) and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function.


Pssm-ID: 270288 [Multi-domain]  Cd Length: 281  Bit Score: 134.49  E-value: 4.31e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464  30 SYILATASTGGTYYPVGVALATLskvkLAPKQHFSLAAISSAGSGENVKLLNENEAQFAILQGLYGAWAWQGLGPYEKSG 109
Cdd:cd13570    1 SLTIGTASQGGTYYVYGGGWANL----LEEELGVPASAEVTGGPVQNLALVHNGELDLGMVTMGPAFEAYNGEGDLTPGV 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 110 RQTQLRSVSMLWQNVEHFIVrsdLAKTGtVSDLENLNGKKFSIGKKNSGTENSGRQIMQGLSVNpeqFKLAFMGYGGSAS 189
Cdd:cd13570   77 KMDDVRALFPMYPTPFQIWA---LADSG-ISSIDDLAGKRVGSGPAGGTSGTYFPAILETLGLK---AEVRNGGWSDLAS 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628464 190 ALQNGTIDGMNTPAGVPVGAVTQAFAAlgEDIQILSFTDAQIKQANGDYNIWTKYEIPANTYPGVDKPITTIAQPNFLAV 269
Cdd:cd13570  150 QLQDGQLDAVAFAAGVPIPAVMELEAQ--TEINILGVTGEEISKLIEEYPYWSEFTIPAGTYKALKEDIQTISMWNFAIA 227
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 515628464 270 REDISEDDVYQLTKAIYENLPFLQGIHKATKAMALEKGIAGLPVPLHPGAARYY 323
Cdd:cd13570  228 HKDLPEDLVYEITKAVFENNDQMINTHKSAAETVPENVTKNTFLPFHPGAIRYY 281
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH